Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Anidulafungin for the treatment of candidaemia caused by Candida parapsilosis: Analysis of pooled data from six prospective clinical studies. | Concerns with echinocandin use for infections caused by Candida parapsilosis complex species have driven the need for data to support echinocandin clinical efficacy in such patients. Data from six prospective studies were pooled to assess efficacy and safety of anidulafungin in patients with candidaemia caused by C. pa... | ['Administration, Intravenous', 'Adult', 'Anidulafungin', 'Antifungal Agents', 'Azoles', 'Candida parapsilosis', 'Candidemia', 'Candidiasis, Invasive', 'Clinical Trials as Topic', 'Echinocandins', 'Female', 'Fluconazole', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Prospective Studies', 'Treatment ... | 28,597,967 | [['E02.319.267.082'], ['M01.060.116'], ['D12.644.641.311.250'], ['D27.505.954.122.136'], ['D03.383.129'], ['B01.300.107.795.095.600', 'B01.300.381.147.600', 'B01.300.930.176.600'], ['C01.150.703.160.175.500', 'C01.150.703.492.500.500', 'C01.757.360.150', 'C23.550.470.790.500.360.150'], ['C01.150.703.160.175', 'C01.150.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quality of life and healthcare resource use associated with angiographic vasospasm after aneurysmal subarachnoid hemorrhage. | BACKGROUND AND PURPOSE: In this analysis of data from a large clinical trial in aneurysmal subarachnoid hemorrhage, the impact of angiographic vasospasm (aVSP) on specific patient outcomes and inpatient healthcare resource use was assessed.METHODS: This was a post hoc analysis of exploratory end points collected for 40... | ['Adolescent', 'Adult', 'Aged', 'Cerebral Angiography', 'Cognition', 'Cognition Disorders', 'Double-Blind Method', 'Female', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Quality of Health Care', 'Quality of Life', 'Subarachnoid Hemorrhage', 'Time Factors', 'Vasospasm, Intracranial'] | 22,328,549 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['F02.463.188'], ['F03.615.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Nuclear magnetic resonance: a review of principles and applications in medicine and chiropractic. | Nuclear Magnetic Resonance (NMR) has in principle been known since 1946 and has found many applications in the fields of physics and chemistry. However, although it has only been in recent years that it has found potential use in various fields of medicine, it is rapidly proceeding from research and development to the ... | ['Chiropractic', 'Costs and Cost Analysis', 'Forecasting', 'Magnetic Resonance Spectroscopy', 'Physical Phenomena', 'Physics'] | 6,655,375 | [['H02.110'], ['N03.219.151'], ['I01.320'], ['E05.196.867.519'], ['G01'], ['H01.671']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Visible light-cured composite resins: polymerization contraction, contraction pattern and hygroscopic expansion. | The wall-to-wall polymerization contraction and hygroscopic expansion of Durafill, Heliosit, Silux and Visio-Dispers were examined in dentin cavities in extracted human teeth. The linear shrinkage varied from 0.24% to 0.63% and only two of the tested materials were able to close the marginal gap owing to water absorpti... | ['Absorption', 'Chemical Phenomena', 'Chemistry, Physical', 'Composite Resins', 'Dental Bonding', 'Dental Cavity Preparation', 'Dental Restoration, Permanent', 'Humans', 'Light', 'Surface Properties'] | 6,753,102 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['G02'], ['H01.181.529'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.095'], ['E06.931.325'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['B01.050.150.... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Rapid diagnosis of group B streptococcal infection utilizing a commercially available latex agglutination assay. | The Wellcogen Strep B latex assay rapidly identifies all cases of culture-positive sepsis and meningitis and may be more sensitive than standard culture techniques for identifying group B Streptococcus disease and assessing the degree of severity. The quantitation of antigen concentration combined with the peripheral W... | ['Antigens, Bacterial', 'Humans', 'Infant, Newborn', 'Latex Fixation Tests', 'Leukocyte Count', 'Neutrophils', 'Streptococcal Infections', 'Streptococcus agalactiae'] | 6,361,678 | [['D23.050.161'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.812.735.050.450', 'E05.200.812.735.050.450', 'E05.478.594.760.050.450'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autotrophy as a predominant mode of carbon fixation in anaerobic methane-oxidizing microbial communities. | The methane-rich, hydrothermally heated sediments of the Guaymas Basin are inhabited by thermophilic microorganisms, including anaerobic methane-oxidizing archaea (mainly ANME-1) and sulfate-reducing bacteria (e.g., HotSeep-1 cluster). We studied the microbial carbon flow in ANME-1/ HotSeep-1 enrichments in stable-isot... | ['Anaerobiosis', 'Autotrophic Processes', 'Bacteria', 'Biota', 'Carbon', 'Carbon Cycle', 'Carbon Isotopes', 'Isotope Labeling', 'Lipid Metabolism', 'Methane', 'Mexico', 'Molecular Sequence Data', 'Oxidation-Reduction'] | 23,129,626 | [['G02.111.062', 'G03.078'], ['G02.111.071', 'G03.087'], ['B03'], ['G16.500.275.157.049.100', 'N06.230.124.049.100'], ['D01.268.150'], ['G02.607.125', 'G16.500.150'], ['D01.268.150.075', 'D01.496.123'], ['E05.522'], ['G03.458'], ['D02.455.326.146.571'], ['Z01.107.567.589'], ['L01.453.245.667'], ['G02.700', 'G03.295.531... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Liposoluble vitamins E and A in human renal cortex and renal cell carcinomas. | Vitamin E was quantified in renal cell carcinomas (RCC) and in 'intact' renal cortex, obtained from 31 patients subjected either to unilateral nephrectomy or to partial resection of the only kidney. Histologically, 14 tumors consisted predominantly of clear cells (group 1) and 17 of other cell types (group 2). In both ... | ['Adult', 'Aged', 'Carcinoma, Renal Cell', 'Female', 'Humans', 'Kidney Cortex', 'Kidney Neoplasms', 'Lipid Metabolism', 'Male', 'Middle Aged', 'Solubility', 'Vitamin A', 'Vitamin E'] | 7,777,111 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.324'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modelling the sulfoxygenation activity of vanadate-dependent peroxidases. | Vanadate-dependent peroxidases contain, in their active center, vanadate covalently attached to histidine in an overall trigonal-bipyramidal array. We describe here the synthesis and characterization of optically active amino alcohols and their vanadium(V) complexes, and we show that the structural models of the active... | ['Catalysis', 'Crystallography, X-Ray', 'Ethanolamines', 'Ligands', 'Models, Chemical', 'Molecular Structure', 'Organometallic Compounds', 'Peroxidases', 'Silicon Dioxide', 'Sulfones', 'Sulfoxides', 'Sulfur Compounds', 'Vanadium'] | 18,972,532 | [['G02.130'], ['E05.196.309.742.225'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D27.720.470.480'], ['E05.599.495'], ['G02.111.570', 'G02.466'], ['D02.691'], ['D08.811.682.732'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['D02.886.590'], ['D02.886.640'], ['D01.875', 'D02.886'], ['D01.268.556... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of the vitamin D receptor genotype with bone metastases in breast cancer patients. | This study was designed in order to evaluate specific vitamin D receptor (VDR) genotypes as indicators of the likelihood of developing osseous metastases in breast cancer patients. Therefore, we determined polymorphisms of the VDR gene in a study group comprising 183 breast cancer patients. Specific fragments spanning ... | ['Bone Neoplasms', 'Breast Neoplasms', 'Female', 'Genotype', 'Humans', 'Middle Aged', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Receptors, Calcitriol'] | 12,566,913 | [['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.393.620.500'], ['G05.365.795'], ['D12.776.826.535']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
First report of the efficacy of vestibular rehabilitation in improving function in patients with Neurofibromatosis type 2: an observational cohort study in a clinical setting. | PURPOSE: Patients with Neurofibromatosis type 2 often experience debilitating neuro-otological problems which affect their mobility and balance. This study examined the efficacy of a personalised program of vestibular rehabilitation for patients with Neurofibromatosis type 2.MATERIALS AND METHODS: An observational coho... | ['Accidental Falls', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurofibromatosis 2', 'Physical Therapy Modalities', 'Postural Balance', 'Vestibular Diseases'] | 29,558,230 | [['N06.850.135.122'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.465.625.650.595.610.500', 'C04.557.580.600.580.590.655', 'C04.557.580.600.610.595.610.500', 'C04.700.631.655', 'C09.218.807.800.675.500', '... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Maternal zinc restriction affects postnatal growth and glucose homeostasis in rat offspring differently depending upon adequacy of their nutrient intake. | INTRODUCTION: We have previously investigated effects of moderate maternal zinc (Zn) restriction on growth and glucose homeostasis in offspring, but interaction between maternal Zn restriction and postnatal nutrition have not been studied.RESULTS: Weight and serum Zn were lower in ZnD-IN than in ZnC-IN rats at wk 3, bu... | ['Animals', 'Animals, Newborn', 'C-Peptide', 'Female', 'Glucose', 'Homeostasis', 'Insulin', 'Insulin Resistance', 'Insulin-Like Growth Factor I', 'Leptin', 'Male', 'Models, Animal', 'Nutritional Status', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Sprague-Dawley', 'Sex Characteristics', 'Zinc'] | 22,278,188 | [['B01.050'], ['B01.050.050.282'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['D09.947.875.359.448'], ['G07.410'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Changes in salivary nitrophorin profile during the life cycle of the blood-sucking bug Rhodnius prolixus. | The insect Rhodnius prolixus is a hematophagous hemipteran that has five nymphal instars. Fifth instar nymphs contain, in their salivary glands, four nitrophorins which have already been described in the literature (NP1, NP2, NP3 and NP4). Two new hemeproteins were isolated and partially characterized from first instar... | ['Amino Acid Sequence', 'Animals', 'Chromatography, High Pressure Liquid', 'Chromatography, Ion Exchange', 'Hemeproteins', 'Life Cycle Stages', 'Molecular Sequence Data', 'Rhodnius', 'Saliva', 'Salivary Proteins and Peptides', 'Sequence Homology, Amino Acid'] | 12,459,197 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.181.400.300'], ['E05.196.181.400.383'], ['D12.776.422'], ['B05.500', 'G07.345.500.550.500'], ['L01.453.245.667'], ['B01.050.500.131.617.412.420.700.850.700'], ['A12.200.666'], ['D12.644.848', 'D12.776.850'], ['G02.111.810.200', 'G05.810.200']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Age-related decline in ovarian follicle stocks differ between chimpanzees (Pan troglodytes) and humans. | Similarity in oldest parturitions in humans and great apes suggests that we maintain ancestral rates of ovarian aging. Consistent with that hypothesis, previous counts of primordial follicles in postmortem ovarian sections from chimpanzees (Pan troglodytes) showed follicle stock decline at the same rate that human stoc... | ['Adolescent', 'Adult', 'Aging', 'Animals', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Middle Aged', 'Ovarian Follicle', 'Ovarian Reserve', 'Pan troglodytes', 'Young Adult'] | 25,651,885 | [['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.630'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['G08.686.210.249', 'G08.686.628'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
SURVIVAL UNTIL DISCHARGE OF VERY-LOW-BIRTH-WEIGHT INFANTS IN TWO CROATIAN PERINATAL CARE REGIONS: A RETROSPECTIVE COHORT STUDY OF TIME AND CAUSE OF DEATH. | We investigated mortality, causes, timing and risk factors for death until hospital discharge in very-low-birth-weight (VLBW) infants born in two Croatian perinatal care regions. This retrospective study included 252 live born VLBW infants. The mortality rate until hospital discharge was 30.5% (77/252). VLBW infants wh... | ['Cause of Death', 'Croatia', 'Female', 'Gestational Age', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Infant, Very Low Birth Weight', 'Male', 'Patient Discharge', 'Perinatal Care', 'Retrospective Studies', 'Risk Factors', 'Survival Analysis'] | 31,969,756 | [['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['Z01.542.248.295'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Narcissism and the personal myth. | Kris (1956) described the concept of the personal myth as an autobiographical story built around a family romance fantasy seen specifically in obsessive characters and serving a defensive function. In this paper the concept of the personal myth was expanded to include similar defensive constellations originating from w... | ['Creativity', 'Defense Mechanisms', 'Fantasy', 'Humans', 'Literature, Modern', 'Male', 'Narcissism', 'Neurotic Disorders', 'Personality Disorders', 'Poetry as Topic', 'Psychoanalytic Interpretation', 'Psychoanalytic Theory'] | 3,749,397 | [['F01.752.264', 'F02.463.785.302'], ['F01.393'], ['F01.393.351', 'F02.463.188.634.507'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.517.533'], ['F02.739.794.582'], ['F03.080.550', 'F03.650'], ['F03.675'], ['K01.517.781'], ['F04.628'], ['F02.739.794']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The clinical effect of a new infant formula in term infants with constipation: a double-blind, randomized cross-over trial. | BACKGROUND: Nutrilon Omneo (new formula; NF) contains high concentration of sn-2 palmitic acid, a mixture of prebiotic oligosaccharides and partially hydrolyzed whey protein. It is hypothesized that NF positively affects stool characteristics in constipated infants.METHODS: Thirty-eight constipated infants, aged 3-20 w... | ['Constipation', 'Cross-Over Studies', 'Defecation', 'Double-Blind Method', 'Female', 'Humans', 'Infant', 'Infant Formula', 'Infant, Newborn', 'Lactose', 'Linoleic Acid', 'Male', 'Milk Proteins', 'Multivariate Analysis', 'Oligosaccharides', 'Palmitic Acid', 'Treatment Outcome', 'Whey Proteins'] | 17,428,343 | [['C23.888.821.150'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G10.261.165'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.100.712.249', 'G07.203.300.525.350.500', 'G07.203.30... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Identification of a ToxR-activated gene, tagE, that lies within the accessory colonization factor gene cluster of Vibrio cholerae O395. | The nucleotide (nt) sequence has been determined for a Vibrio cholerae ToxR-activated gene designated tagE that is located within a cluster of genes required for efficient intestinal colonization. The tagE gene encompasses 909 nt and is predicted to encode a 303-amino-acid (aa) protein with an estimated molecular mass ... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'DNA-Binding Proteins', 'Fimbriae Proteins', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Molecular Sequence Data', 'Multigene Family', 'RNA, Bacterial', 'RNA, Messenger', 'Regulon', 'Sequence Analysis, DNA', 'Sequence Homology, Amino Acid'... | 7,523,253 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260'], ['D12.776.097.120.425', 'D12.776.543.100.300'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['L01.453.245.667'], ['G05.360... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Factors affecting bony impingement in hip arthroplasty. | Computer modeling of 10 patients' computed tomographic scans was used to study the variables affecting hip arthroplasty range of motion before bony impingement (ROMBI) including acetabular offset and height, femoral offset, height and anteversion, and osteophyte removal. The ROMBI was compared with the ROM before compo... | ['Acetabulum', 'Algorithms', 'Arthroplasty, Replacement, Hip', 'Computer Simulation', 'Female', 'Femur Head', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis, Hip', 'Osteophyte', 'Range of Motion, Articular', 'Tomography, X-Ray Computed'] | 19,559,561 | [['A02.835.232.043.825.108'], ['G17.035', 'L01.224.050'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['L01.224.160'], ['A02.835.232.043.150.343'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606.400', 'C05.799.613.400'], ['C05.116.540.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Comparison of four extraction/methylation analytical methods to measure fatty acid composition by gas chromatography in meat. | Four different extraction-derivatization methods commonly used for fatty acid analysis in meat (in situ or one-step method, saponification method, classic method and a combination of classic extraction and saponification derivatization) were tested. The in situ method had low recovery and variation. The saponification ... | ['Chromatography, Gas', 'Fatty Acids', 'Meat', 'Methylation', 'Reference Standards', 'Reproducibility of Results'] | 18,367,195 | [['E05.196.181.349'], ['D10.251'], ['G07.203.300.600', 'J02.500.600'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['E05.978.808'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Treatment outcomes of heparin-induced thrombocytopenia in subarachnoid hemorrhage patients: a 4-year, retrospective single-center review. | INTRODUCTION: The treatment and outcomes of heparin-induced thrombocytopenia (HIT) are not well described in neurosurgery patients. This study reviewed the treatment for HIT in subarachnoid hemorrhage (SAH) patients, and compared outcomes in patients with isolated HIT (iHIT) and HIT with thrombotic syndrome (HITTS).MET... | ['Adult', 'Aged', 'Antibodies, Anti-Idiotypic', 'Anticoagulants', 'Arginine', 'Female', 'Fondaparinux', 'Heparin', 'Humans', 'Immunoglobulin G', 'Male', 'Middle Aged', 'Pipecolic Acids', 'Platelet Aggregation Inhibitors', 'Platelet Factor 4', 'Polysaccharides', 'Purpura, Thrombotic Thrombocytopenic', 'Retrospective Stu... | 22,692,920 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D27.505.954.502.119'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D09.698.629.429'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Silencing of MEOX1 Gene Inhibits Proliferation and Promotes Apoptosis of LNCaP Cells in Prostate Cancer. | BACKGROUND: Prostate cancer (PC), the most commonly diagnosed malignancy, is also the second leading cause of cancer-related deaths. Although tremendous efforts have been achieved to improve the early detection of PC, it is still urgent to find out novel markers and therapeutic targets for PC patients. Homeobox protein... | ['Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Gene Silencing', 'Heterografts', 'Homeodomain Proteins', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Prostatic Neoplasms', 'RNA, Small Interfering', 'Transcription Factors', 'Transcriptome', 'Transfection'] | 30,543,460 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.203.374'], ['A01.941.875'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.52... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spontaneous mutation at codon 61 of the Ha-ras gene in the nascent liver of B6C3F1, C3H/He and C57BL/6 mice. | DNA was isolated from the liver of young B6C3F1, C3H/He and C57BL/6 mice, 6-9 weeks old. A portion of exon 2 of Ha-ras was amplified by PCR allele-specific amplification. The PCR product was identified by (a) size, (b) presence of a diagnostic restriction site, and (c) direct sequencing. Our results indicate that nasce... | ['Animals', 'Base Sequence', 'Codon', 'DNA', 'Female', 'Genes, ras', 'Liver', 'Male', 'Mice', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'Mutation'] | 7,526,162 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308'], ['G05.360.340.024.340.375.500.791.550'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Observational: prospective study of indirect pulp treatment in primary molars using resin-modified glass ionomer and 2% chlorhexidine gluconate: a 12-month Follow-up. | PURPOSE: This study's purpose was to determine the efficacy of indirect pulp treatment (IPT) in primary molars when using 2% chlorhexidine gluconate disinfecting solution and resin-modified glass ionomer (RMGI) liner after 12 months.METHODS: Three- to 10-year-old subjects with deep carious lesions who met selection cri... | ['Anti-Infective Agents, Local', 'Child', 'Child, Preschool', 'Chlorhexidine', 'Composite Resins', 'Crowns', 'Dental Caries', 'Dental Cavity Lining', 'Dental Cavity Preparation', 'Dental Materials', 'Dental Pulp Capping', 'Dental Restoration, Permanent', 'Dentin', 'Female', 'Follow-Up Studies', 'Glass Ionomer Cements',... | 23,635,886 | [['D27.505.954.122.187'], ['M01.060.406'], ['M01.060.406.448'], ['D02.078.370.141.100'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.780.346.250', 'E07.695.190.088'], ['C07.793.720.210'], ['E06.323.225'], ['E06.931.325'], ['D25.339',... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Has the yearly increase in the renal replacement therapy population ended? | The recent decline in the number of new patients undergoing dialysis and transplantation in the United States may be linked to a reduction in the incidence of early-start dialysis, defined as the initiation of renal replacement therapy (RRT) at an estimated GFR ?10 ml/min per 1.73 m(2). We examined the most recent data... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Canada', 'Child', 'Child, Preschool', 'Glomerular Filtration Rate', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Kidney Failure, Chronic', 'Middle Aged', 'Registries', 'Renal Replacement Therapy', 'Retrospective Studies', 'United States', 'You... | 23,868,925 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.176'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', ... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo. | The sensory hair cells of the inner ear undergo apoptosis after acoustic trauma or aminoglycoside antibiotic treatment, causing permanent auditory and vestibular deficits in humans. Previous studies have demonstrated a role for caspase activation in hair cell death and ototoxic injury that can be reduced by concurrent ... | ['Amino Acid Chloromethyl Ketones', 'Aminoglycosides', 'Animals', 'Apoptosis', 'Calbindin 2', 'Caspase Inhibitors', 'Cell Survival', 'Chickens', 'Cysteine Proteinase Inhibitors', 'Drug Administration Routes', 'Eye Movements', 'Hair Cells, Vestibular', 'Infusion Pumps, Implantable', 'Photic Stimulation', 'Reflex, Vestib... | 12,853,430 | [['D12.125.065'], ['D09.408.051'], ['B01.050'], ['G04.146.954.035'], ['D12.776.157.125.090.249'], ['D27.505.519.389.745.325.500'], ['G04.346'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D27.505.519.389.745.325'], ['E02.319.267'], ['G11.427.410.140', 'G14.350'], ['A08.675.650.395', 'A08.675.650.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Study of the functional structure of the EEG by means of the ambispectrum and ambicoherence (author's transl)]. | An extension of spectral analysis by calculation of the ambispectrum and ambicoherence is defined, tested on pulsed and random signals, and then applied to the study of the functional structure of the electro-encephalogram. Preliminary results are similar to those obtained by the use of the biospectrum and bicoherence,... | ['Alpha Rhythm', 'Electroencephalography', 'Humans', 'Mathematics'] | 7,465,945 | [['E01.370.376.300.150.374', 'E01.370.405.245.287.374', 'G07.265.087.500', 'G11.561.127.500'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Monosymptomatic hypochondriacal psychoses: a diagnostic entity which may respond to pimozide. | Monosymptomatic hypochondriacal psychoses are akin to paranoia. Although presenting with a variety of delusional complaints in individual cases, the condition appears to represent a relatively dis crete diagnostic entity. It is less rare than usually thought, but those afflicted frequently to to the physical specialtie... | ['Adult', 'Delusions', 'Dose-Response Relationship, Drug', 'Humans', 'Hypochondriasis', 'Male', 'Pimozide', 'Psychotic Disorders'] | 709,499 | [['M01.060.116'], ['F01.145.126.200'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.875.450'], ['D03.633.100.103.732'], ['F03.700.675']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An Innovative Simulation-based Community-engaged Intervention for Training Research Assistants in Culturally Appropriate Informed Consent. | BACKGROUND: Enrolling under-represented groups in biomedical research remains challenging owing to limited health literacy, historic medical abuses, and mistrust. Addressing such barriers requires scrutiny of informed consent processes and training of research assistants (RAs). Applying simulation methods that are well... | ['Community-Based Participatory Research', 'Culturally Competent Care', 'Diffusion of Innovation', 'Health Services Research', 'Humans', 'Informed Consent', 'Pilot Projects', 'Research Design', 'Research Personnel', 'Simulation Training', 'United States'] | 30,581,168 | [['H01.770.644.193', 'N05.425.104'], ['N04.590.374.052', 'N05.300.206'], ['L01.143.320'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['E05.318.372.750', 'E05.337.737', '... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
[Immunological profile of coeliac disease in a subgroup of patients with symptoms of irritable bowel syndrome]. | AIM: The purpose of this study was to determine if authentic cases of irritable bowel syndrome could be secondary in a latent or potential coeliac disease.METHODS: All new patients who consulted for irritable bowel syndrome fulfilling Rome II criteria between 01/04/2003 and 30/03/2004 were included. All patients had up... | ['Adult', 'Aged', 'Celiac Disease', 'Female', 'Humans', 'Irritable Bowel Syndrome', 'Male', 'Middle Aged', 'Prospective Studies', 'Young Adult'] | 19,472,779 | [['M01.060.116'], ['M01.060.116.100'], ['C06.405.469.637.250', 'C18.452.603.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.158.272.608'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['M01.060.116.815']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Peripherally evoked single unit responses in ventroposterolateral nucleus in the absence of the dorsal column nuclei in rat. | The present experiments were designed to determine the effects of removing the dorsal column nuclei on the evoked responses of the ventroposterolateral nucleus (VPL) neurons in the rat. Previously, we have observed inhibitory interactions between forelimb and hindlimb inputs to VPL (Roberts and Wells 1990), and have al... | ['Animals', 'Brachial Plexus', 'Electric Stimulation', 'Evoked Potentials', 'Forelimb', 'Functional Laterality', 'Hindlimb', 'Neurons', 'Rats', 'Rats, Inbred Strains', 'Sciatic Nerve', 'Spinal Cord', 'Time Factors'] | 1,855,555 | [['B01.050'], ['A08.800.800.720.050'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'], ['A13.395'], ['F02.830.297.425', 'G11.561.225.425'], ['A13.473'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A08.800.800... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induced mRNA stability in Bacillus subtilis. | We have investigated the induced stability of mRNA encoded by the ermC gene in Bacillus subtilis. Induction of ermC gene expression by erythromycin is known to occur at the translational level. We show that this induction is accompanied by an increase in ermC mRNA half-life from about 2 min to about 40 min. Induced sta... | ['Bacillus subtilis', 'Base Sequence', 'Drug Stability', 'Genes, Bacterial', 'Nucleic Acid Conformation', 'Plasmids', 'Protein Biosynthesis', 'RNA, Messenger'] | 3,099,297 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.916.330'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G02.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Temporal properties of inputs to direction-selective neurons in monkey V1. | Motion in the visual scene is processed by direction-selective neurons in primary visual cortex. These cells receive inputs that differ in space and time. What are these inputs? A previous single-unit recording study in anesthetized monkey V1 proposed that the two major streams arising in the primate retina, the M and ... | ['Action Potentials', 'Animals', 'Macaca nemestrina', 'Motion Perception', 'Neurons', 'Orientation', 'Photic Stimulation', 'Reaction Time', 'Space Perception', 'Time Factors', 'Visual Cortex', 'Visual Fields', 'Visual Pathways'] | 15,744,011 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.510.560'], ['F02.463.593.932.567'], ['A08.675', 'A11.671'], ['F01.058.577', 'F02.830.606'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.778'], ['G01.910.857... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization and mutual ligand-induced modulation of epidermal growth factor and interferon-alpha receptors on renal carcinoma cells in vitro. | We have determined the binding of epidermal growth factor (EGF) and interferon (IFN)-alpha to their specific receptors on four renal carcinoma cell lines. CaKi-2, a-498 and ACHN cell lines express high numbers, and CaKi-1 expresses low number of EGF receptors (EGFRs). On all four renal carcinoma cell lines, we have als... | ['Adenocarcinoma', 'Binding, Competitive', 'Carcinoma', 'ErbB Receptors', 'Humans', 'Kidney Neoplasms', 'Receptor, Interferon alpha-beta', 'Receptors, Interferon', 'Tumor Cells, Cultured'] | 8,845,479 | [['C04.557.470.200.025'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['C04.557.470.200'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
How Entrustment Is Informed by Holistic Judgments Across Time in a Family Medicine Residency Program: An Ethnographic Nonparticipant Observational Study. | PURPOSE: Entrustment has mainly been conceptualized as delegating discrete professional tasks. Because residents provide most of their patient care independently, not all resident performance is visible to supervisors; the entrustment process involves more than granting discrete tasks. This study explored how superviso... | ['Adult', 'Attitude of Health Personnel', 'Clinical Competence', 'Decision Making', 'Family Practice', 'Female', 'Humans', 'Internship and Residency', 'Interprofessional Relations', 'Judgment', 'Male', 'Netherlands', 'Physicians', 'Students, Medical', 'Young Adult'] | 28,557,945 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F02.463.785.373'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F01.829.401.205'], ['F02.463.785.626'], ['Z01.542.651'], ['M01.526.485.810', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Maximal fitness testing in sedentary elderly at substantial risk of disability: LIFE-P study experience. | BACKGROUND: The authors sought to evaluate the acceptability and feasibility of maximal fitness testing in sedentary older individuals at risk for mobility disability.METHODS: Maximal cycle-ergometer testing was performed at baseline and 6 and 12 months later in a subset of LIFE-P study participants at the Cooper Insti... | ['Activities of Daily Living', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Bicycling', 'Disabled Persons', 'Ergometry', 'Exercise Test', 'Feasibility Studies', 'Female', 'Health Status Indicators', 'Humans', 'Male', 'Muscle, Skeletal', 'Oxygen Consumption', 'Physical Fitness', 'Pilot Projects', 'Risk', 'Time Factors'] | 19,033,602 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['I03.450.642.845.140'], ['M01.150'], ['E05.333'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E05.318.372.550', 'E05.337.675', 'N05.715.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Geraniol-derived 1,2,4-trioxanes with potent in-vivo antimalarial activity. | Geraniol, an abundantly available naturally occurring allylic alcohol, has been used as a starting material to prepare a series of 6-[alpha-(3'-aryl-3'-hydroxypropyl)vinyl]-1,2,4-trioxanes. Some of these novel trioxanes have shown very promising antimalarial activity against multi-drug resistant Plasmodium yoelii in mi... | ['Acyclic Monoterpenes', 'Animals', 'Antimalarials', 'Malaria', 'Mice', 'Plasmodium yoelii', 'Terpenes'] | 14,505,646 | [['D02.455.849.575.125'], ['B01.050'], ['D27.505.954.122.250.100.085'], ['C01.610.752.530', 'C01.920.875'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.043.075.380.611.780'], ['D02.455.849']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrical stimulation of the urethra evokes bladder contractions and emptying in spinal cord injury men: case studies. | OBJECTIVE: Electrical stimulation of the urethra can evoke bladder contractions in persons with spinal cord injury (SCI). The objective of this study was to determine whether electrical stimulation of the urethra could evoke bladder contractions that empty the bladder.METHODS: The first patient was a 45-year-old man wi... | ['Biophysics', 'Electric Stimulation', 'Electromyography', 'Humans', 'Male', 'Middle Aged', 'Muscle, Smooth', 'Spinal Cord Injuries', 'Urethra', 'Urination', 'Urodynamics'] | 21,756,572 | [['H01.158.344', 'H01.671.100'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.570', 'A10.690.467'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['A05.360.444.492.726', 'A05.810.876'], ['G08.852.880'], ['G08.852.898']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The relation between supraventricular tachyarrhythmias and left ventricular dysfunction after acute myocardial infarction. | The clinical characteristics of supraventricular tachyarrhythmias (SVTA) and their relation to left ventricular dysfunction were assessed in 208 consecutive patients with recent myocardial infarction. Arrhythmias were quantified on hospital discharge by 24 hour electrocardiographic recording. All the variables were eva... | ['Adult', 'Aged', 'Aged, 80 and over', 'Atrial Fibrillation', 'Atrial Flutter', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Myocardial Infarction', 'Risk Factors', 'Tachycardia, Ectopic Atrial', 'Tachycardia, Ect... | 3,266,415 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.198', 'C23.550.073.198'], ['C14.280.067.248', 'C23.550.073.248'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['A07.541.560'], ['B01.0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Critical role of C-terminal residues of the Alzheimer's associated â-amyloid protein in mediating antiviral activity and modulating viral and bacterial interactions with neutrophils. | Recent studies have shown that the Alzheimer's associated â-amyloid protein (âA) can inhibit growth of bacteria, fungi and viruses. We reported that the 42 amino acid âA protein inhibits replication of seasonal and pandemic strains of H3N2 and H1N1 influenza A virus (IAV) in vitro and modulates activation of neutrophil... | ['Alzheimer Disease', 'Amino Acids', 'Amyloid beta-Peptides', 'Antiviral Agents', 'Bacteria', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza A Virus, H3N2 Subtype', 'Monocytes', 'Neutrophils', 'Respiratory Burst', 'Virus Replication'] | 29,547,627 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.125'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D27.505.954.122.388'], ['B03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['B04.820.480.968.405.400.300'], ['A11.118.637.555.652', 'A1... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Shifting role of operative and nonoperative interventions in managing complications after pancreatoduodenectomy: what is the preferred intervention? | INTRODUCTION: Operative complications after pancreatoduodenectomy can be managed by nonoperative or operative interventions. The aim of this study was to analyze the shift in management of five major complications and their success rates. An algorithm was developed according to predictors for type of intervention and f... | ['Abscess', 'Aged', 'Algorithms', 'Anastomotic Leak', 'Cohort Studies', 'Female', 'Hemorrhage', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Diseases', 'Pancreatic Fistula', 'Pancreatic Neoplasms', 'Pancreaticoduodenectomy', 'Postoperative Complications', 'Prospective Studies', 'Sepsis', 'Time Factors', 'Treatment Outc... | 25,017,138 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['C23.550.767.071'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689'], ['C06.267.775', 'C06.689.583',... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Baseline respiratory sinus arrhythmia and heart rate responses during sustained visual attention in preterm infants from 3 to 6 months of age. | Three groups of preterm infants were studied longitudinally at 14, 20, and 26 weeks of age (corrected for gestational age). The groups included infants with no perinatal medical complications, those with mild respiratory problems requiring ventilatory assistance, and those with respiratory distress syndrome. Baseline h... | ['Age Factors', 'Arousal', 'Arrhythmia, Sinus', 'Asphyxia Neonatorum', 'Attention', 'Female', 'Heart Rate', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Longitudinal Studies', 'Male', 'Psychophysiology', 'Respiration', 'Respiratory Distress Syndrome, Newborn', 'Visual Perception'] | 8,008,787 | [['N05.715.350.075', 'N06.850.490.250'], ['F02.830.104', 'G11.561.035'], ['C14.280.067.093', 'C23.550.073.093'], ['C16.614.092'], ['F02.830.104.214'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C16.614.521'], ['E05.318.372.500.750... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A childhood malignant rhabdoid tumour of the kidney. | A case report is presented of a malignant rhabdoid tumour occurring in the kidney of a 23-month-old boy. Important differences between this and the conventional Wilms' tumour include the histological demonstration of sheets or cords of large cells resembling myoblasts, a tendency to frequent clinical relapse, and a hig... | ['Humans', 'Infant', 'Kidney Neoplasms', 'Male', 'Rhabdoid Tumor'] | 12,501,552 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.557.435.710']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Triterpenes from Mucuna birdwoodiana. | Methanolic extracts of the stalks of Mucuna birdwoodiana on acid hydrolysis and subsequent methylation with diazomethane provided four triterpene sapogenols. On the other hand, investigation of glycosides after methylation of the same extract led to the isolation of four triterpene glycosides. On the basis of chemical ... | ['Carbohydrate Sequence', 'Fabaceae', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Molecular Structure', 'Plants, Medicinal', 'Triterpenes'] | 1,367,838 | [['G02.111.570.160', 'L01.453.245.667.160'], ['B01.650.940.800.575.912.250.401'], ['E05.196.867.519'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['B01.650.560'], ['D02.455.849.919']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mapping economic trait loci for somatic cell score in Holstein cattle using microsatellite markers and selective genotyping. | Marker-assisted selection (MAS) uses genetic marker genotypes to predict an animal's production potential and will provide additional selection information for progeny testing. With the discovery of highly polymorphic microsatellite markers, the tools now exist to begin the search for economic trait loci (ETL), which i... | ['Alleles', 'Animals', 'Cattle', 'DNA, Satellite', 'Female', 'Genotype', 'Lactation', 'Male', 'Microsatellite Repeats', 'Milk', 'Models, Genetic', 'Models, Theoretical', 'Polymerase Chain Reaction', 'Semen'] | 8,856,920 | [['G05.360.340.024.340.030'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['G05.380'], ['G08.686.523', 'G08.686.702.500'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.5... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Concept of a force-measuring horseshoe. | To further develop objective methods in the field of gait analysis a force-measuring horseshoe (FM shoe) has been developed. The ground reaction forces were determined by measuring the degree of displacement between the two solid parts of the shoe. This was done by three removable measuring units (MUs) that were equipp... | ['Animal Husbandry', 'Animals', 'Calibration', 'Equipment Design', 'Gait', 'Horses', 'Physiology'] | 8,470,452 | [['J01.040.090'], ['B01.050'], ['E05.978.155'], ['E05.320'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.984.235.472'], ['H01.158.782']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A measure of school racial socialization and quality of intergroup interactions. | OBJECTIVES: The current study presents a comprehensive framework of campus racial climate and tests the validity and reliability of a new measure, the School Climate for Diversity Scale-College, in three independent samples. The scale measures 10 dimensions of campus racial climate in the two domains of intergroup inte... | ['Continental Population Groups', 'Cultural Competency', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Psychometrics', 'Reproducibility of Results', 'Social Identification', 'Social Perception', 'Socialization', 'Students', 'Surveys and Questionnaires', 'Universities', 'Young Adult'] | 29,952,579 | [['M01.686.508'], ['I01.880.853.100.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['F01.145.813.708'], ['F02.463.593.752'], ['I01.880.853.934'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Hugh Morriston Davies: first dissection lobectomy in 1912. | Hugh Morriston Davies (1879-1965), long before anybody else, performed the first anatomic dissection lobectomy for a tumor of the lung in 1912. By replacing the hilar mass-ligation-suture technique, he was decades ahead of his time, and had his patient not died 8 days after the operation, he would have preceded Evarts ... | ['History, 20th Century', 'Humans', 'Lung Neoplasms', 'Thoracic Surgery', 'United Kingdom'] | 8,215,687 | [['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['H02.403.810.803'], ['Z01.542.363']] | ['Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Diagnostic utility of cell block in fine needle aspiration cytology of thyroid gland. | BACKGROUND: This study was conducted to evaluate the diagnostic utility of cell block material in fine needle aspiration (FNA) of thyroid nodules.DESIGN: A total of 242 thyroid fine need aspirations (FNAs) were performed between January 2015 and December 2015. Of those, all consecutive thyroid FNA cases with cell block... | ['Aged', 'Biopsy, Fine-Needle', 'Female', 'Histocytological Preparation Techniques', 'Humans', 'Male', 'Middle Aged', 'Papanicolaou Test', 'Thyroid Nodule'] | 31,411,821 | [['M01.060.116.100'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.225.500.620', 'E01.370.225.750.600', 'E05.200.500.620', 'E05.200.750.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Concurrent conditions in patients with chronic constipation: a population-based study. | BACKGROUND: Chronic constipation (CC) is a common condition but its concurrent conditions are not well characterized. We measured the prevalence and risk of developing 15 pre-specified concurrent conditions in patients with CC.METHODS: Retrospective cohort study using the Medicaid database of California, utilizing ICD-... | ['California', 'Cohort Studies', 'Constipation', 'Fecal Impaction', 'Female', 'Gastrointestinal Hemorrhage', 'Hemorrhoids', 'Hirschsprung Disease', 'Humans', 'Irritable Bowel Syndrome', 'Male', 'Middle Aged', 'Prevalence', 'Rectum', 'Retrospective Studies'] | 23,071,488 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.888.821.150'], ['C06.405.469.531.424'], ['C06.405.227', 'C23.550.414.788'], ['C06.405.469.860.401', 'C14.907.449'], ['C06.198.439', 'C06.405.469.158.701.439', 'C16.131.314.439'],... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Further comparisons of the [125I]somatomedin A and the [125I]somatomedin C radioreceptor assays of somatomedin peptide. | The GH dependency of somatomedin (SM) peptide content in plasma was assessed using the placental membrane radioreceptor assay (RRA) to measure whole and acid-chromatographed plasma using both [125I]SM A and [125I]SM C. Plasmas from 10 normal children and adults, 11 GH-deficient children before and after therapy with 0.... | ['Acromegaly', 'Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Growth Hormone', 'Humans', 'Hypopituitarism', 'Middle Aged', 'Radioligand Assay', 'Somatomedins'] | 447,802 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Probable walnut-induced anaphylactic reaction in a dog. | BACKGROUND: Anaphylaxis due to nuts is frequent in humans; to the best of the authors' knowledge, it has not been reported previously in dogs.CASE REPORT: A 5-year-old female, intact, Vizsla dog was presented with acute diarrhoea, vomiting, respiratory distress and erythematous wheals. The dog had eaten walnuts, which ... | ['Anaphylaxis', 'Animals', 'Dog Diseases', 'Dogs', 'Female', 'Glucocorticoids', 'Juglans', 'Prednisolone'] | 28,261,916 | [['C20.543.480.099'], ['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.650.940.800.575.912.250.859.750.500.500'], ['D04.210.500.745.432.769.795']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Numerical simulation of canine retraction by sliding mechanics. | BACKGROUND: Bone remodeling laws have been used to simulate the movement of a single tooth, but the calculations for simulating the movement of several teeth simultaneously are time-consuming. The purpose of this article is to discuss a method that allows the simulation of more complex tooth movements.METHODS: A 3-dime... | ['Alveolar Process', 'Bicuspid', 'Bone Remodeling', 'Computer Simulation', 'Cuspid', 'Dental Stress Analysis', 'Elasticity', 'Finite Element Analysis', 'Friction', 'Humans', 'Maxilla', 'Models, Biological', 'Molar', 'Orthodontic Brackets', 'Orthodontic Wires', 'Periodontal Ligament', 'Tooth Movement Techniques'] | 15,877,034 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['A14.549.167.860.150'], ['G11.427.213', 'G16.762.150'], ['L01.224.160'], ['A14.549.167.860.200'], ['E06.308'], ['G01.374.590'], ['E05.355'], ['G01.374.618'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.645', 'A14.521... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence and risk factors of maladaptive behaviour in young children with Autistic Disorder. | BACKGROUND: Children with Autistic Disorder (AD) evidence more co-occurring maladaptive behaviours than their typically developing peers and peers with intellectual disability because of other aetiologies. The present study investigated the prevalence of Clinically Significant maladaptive behaviours during early childh... | ['Autistic Disorder', 'Child Behavior Disorders', 'Child, Preschool', 'Comorbidity', 'Ethnic Groups', 'Female', 'Humans', 'Infant', 'Internal-External Control', 'Interview, Psychological', 'Male', 'Parents', 'Prevalence', 'Risk Factors', 'Severity of Illness Index', 'Sex Distribution', 'United States'] | 18,444,989 | [['F03.625.164.113.500'], ['F03.625.141'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.379'], ['F04.669.599'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.308.985.525... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Identification of novel biomarkers in pediatric primitive neuroectodermal tumors and ependymomas by proteome-wide analysis. | The aim of this study was to identify aberrantly expressed proteins in pediatric primitive neuroectodermal tumors (PNETs) and ependymomas. Tumor tissue of 29 PNET and 12 ependymoma patients was subjected to 2-dimensional difference gel electrophoresis. Gel analysis resulted in 79 protein spots being differentially expr... | ['Adolescent', 'Adult', 'Annexin A1', 'Biomarkers, Tumor', 'Brain Neoplasms', 'Calcium-Binding Proteins', 'Child', 'Child, Preschool', 'Electrophoresis, Gel, Two-Dimensional', 'Ependymoma', 'Humans', 'Immunohistochemistry', 'Infant', 'Neoplasm Proteins', 'Neuroectodermal Tumors, Primitive', 'Proteomics', 'RNA, Messenge... | 17,549,010 | [['M01.060.057'], ['M01.060.116'], ['D12.776.157.125.050.050'], ['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D12.776.157.125'], ['M01.060.406'], ['M01.060.406.448'], ['E05.196.401.250', 'E05.301.300.230'], ['C04.557.465.625.600.380.290', 'C04.557.470.670.380.290', 'C04.557.580.625.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Donor exclusions, discarded blood and transfusion unsuited blood conserves of 2,13 million potential blood donors 1991 to 1994]. | UNLABELLED: German authorities plan to legislate transfusion safety. We report on the efficacy of donor selection, unit pre-release testing, quality assurance and look-back efforts (LBE): Among 2,127,102 visits by 503,971 donors are 8.7% first-time donors. 96% of repeaters present our donor ID-card. We defer 5.6% repea... | ['AIDS Serodiagnosis', 'Blood Banks', 'Blood Donors', 'Blood Transfusion', 'Blood-Borne Pathogens', 'Germany', 'Humans', 'Mass Screening', 'Risk Factors'] | 8,974,711 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['N02.278.065.200'], ['M01.898.313'], ['E02.095.135'], ['B05.155'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of direct increases in renal interstitial hydrostatic pressure on sodium excretion. | This study examined the effect of increases in renal interstitial hydrostatic pressure (PI) on sodium excretion (UNaV) utilizing a direct technique for increasing renal interstitial volume. PI was increased by renal interstitial volume expansion (RIVE) via injection of 50 microliters of a 2% albumin in saline solution ... | ['Animals', 'Extracellular Space', 'Glomerular Filtration Rate', 'Hydrostatic Pressure', 'Kidney', 'Kinetics', 'Rats', 'Rats, Inbred Strains', 'Renal Circulation', 'Sodium'] | 3,354,685 | [['B01.050'], ['A10.082.500', 'A11.284.295'], ['E01.370.390.400.300', 'G08.852.357'], ['G01.374.715.352'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G08.852.725', 'G09.330.100.812'], ['D01.2... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphological Changes of Trichomonas vaginalis Treated by Ornidazole: An In-Vitro Study. | BACKGROUND: Nitroimidazoles, which are drugs that are used to effectively treat Trichomonas vaginalis, alter the structure of the T. vaginalis cell membrane, penetrate into its cytoplasm and nucleus and block cellular metabolism. In this study, we observed the morphological changes that occurred in T. vaginalis during ... | ['Antitrichomonal Agents', 'Ornidazole', 'Time Factors', 'Trichomonas vaginalis'] | 27,349,003 | [['D27.505.954.122.250.100.115'], ['D02.640.672.700', 'D03.383.129.308.658.700'], ['G01.910.857'], ['B01.630.800.808.717']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma prekallikrein: isolation, characterization, and mechanism of activation. | The precursor of the kinin-forming enzyme, prekallikrein, was isolated from rabbit plasma protected from activation during preparatory procedures. Prekallikrein was shown to be a 4.5S gamma(1)-glycoprotein with an isoelectric point of 5.9 and a mol wt of 99,900. The proenzyme was activated at neutral pH by an enzyme fr... | ['Amino Acids', 'Animals', 'Aprotinin', 'Blood Proteins', 'Chromatography, Gel', 'Chromatography, Ion Exchange', 'Electrophoresis, Disc', 'Enzyme Activation', 'Enzyme Precursors', 'Glycoproteins', 'Humans', 'Hydrolysis', 'Iodine Isotopes', 'Isoelectric Focusing', 'Kallikreins', 'Methods', 'Molecular Weight', 'Rabbits',... | 4,536,682 | [['D12.125'], ['B01.050'], ['D12.776.083'], ['D12.776.124'], ['E05.196.181.400.250'], ['E05.196.181.400.383'], ['E05.196.401.402.236', 'E05.301.300.319.403'], ['G02.111.263', 'G03.328'], ['D08.622', 'D12.776.811.243'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['D01.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Free vascularised fibular graft in the treatment of congenital pseudarthrosis of the tibia. | Five cases of congenital pseudarthrosis of the tibia successfully treated by a free vascularised fibular graft are described. Follow-up ranged from 5 to 34 months with a mean of 17.5 months. The technique, which includes radical excision of abnormal bone and soft tissue around the pseudarthrosis, also permits primary b... | ['Child', 'Child, Preschool', 'Female', 'Fibula', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Methods', 'Pseudarthrosis', 'Radiography', 'Tibia'] | 3,968,148 | [['M01.060.406'], ['M01.060.406.448'], ['A02.835.232.043.650.321'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.581'], ['C26.404.468.627'], ['E01.370.350.700'], ['A02.835.232.043.650.883']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Blastocysts derivation from somatic cell fusion with premature oocytes (prematuration somatic cell fusion). | This study was undertaken to investigate the development of immature oocytes after their fusion with male somatic cells expressing red fluorescence protein (RFP). RFP-expressing cells were fused with immature oocytes, matured in vitro and then parthenogenetically activated. Somatic nuclei showed spindle formation, 1st ... | ['Animals', 'Blastocyst', 'Cell Fusion', 'Female', 'Male', 'Oocytes', 'Parthenogenesis', 'RNA, Messenger', 'Sex-Determining Region Y Protein', 'Sheep', 'Swine'] | 26,857,553 | [['B01.050'], ['A16.254.500'], ['E05.242.307', 'G04.155'], ['A05.360.490.690.680', 'A11.497.497.600'], ['G08.686.784.830.500', 'G15.547'], ['D13.444.735.544'], ['D12.776.260.719.049', 'D12.776.660.235.400.750.049', 'D12.776.664.235.400.750.049', 'D12.776.930.823.049'], ['B01.050.150.900.649.313.500.380.791'], ['B01.050... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatic genes altered in expression by food restriction are not influenced by the low plasma glucose level in young male GLUT4 transgenic mice. | Because food restriction (FR) has a profound effect on most tissues, it is plausible that the modulation of aging by FR occurs through cellular processes such as gene expression. The effect of FR in lowering plasma glucose levels has been demonstrated in mice, rats, and nonhuman primates. The consistency of this findin... | ['Animals', 'Blood Glucose', 'Female', 'Food Deprivation', 'Gene Expression', 'Gene Expression Profiling', 'Glucose Transporter Type 4', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Monosaccharide Transport Proteins', 'Muscle Proteins', 'Oligonucleotide Array Sequence Analysis', 'Polymerase Chain... | 15,514,260 | [['B01.050'], ['D09.947.875.359.448.500'], ['F01.658.433'], ['G05.297'], ['E05.393.332'], ['D12.776.157.530.500.500.937', 'D12.776.157.530.937.563.937', 'D12.776.543.585.500.500.937', 'D12.776.543.585.937.625.937'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Experience in thyroglossal duct pathology: clinical case series]. | The thyroglossal duct cyst pathology represents the second cause of bening cervical anomalies in childhood. Diagnosis is mainly clinical. Sistrunk (1920) proposed a surgical technique that is still considered the gold standard for definitive treatment of this condition. A retrospective study was made including patients... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Retrospective Studies', 'Thyroglossal Cyst'] | 27,606,652 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['C04.182.902']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of HIV-1 proteinase by non-peptide carboxylates. | Some simple dicarboxylates are among the first reported non-peptide inhibitors of HIV-1 proteinase. Only weak inhibition (IC50 greater than or equal to 10 microM) was observed but this may be significant since only two potential enzyme-binding groups are present. Dixon plots and preliminary kinetic data are reported an... | ['Arginine', 'Binding Sites', 'Dicarboxylic Acids', 'HIV Protease', 'HIV Protease Inhibitors', 'Kinetics', 'Molecular Structure', 'Spectrometry, Fluorescence', 'Structure-Activity Relationship'] | 2,018,518 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G02.111.570.120'], ['D02.241.081.337'], ['D08.811.277.656.074.500.340', 'D08.811.277.656.300.048.340', 'D08.811.277.656.979.500', 'D12.776.964.775.375.545.750', 'D12.776.964.900.500.625'], ['D27.505.519.389.745.900.500', 'D27.505.954.122.388.077.088.420'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomic Differences in the Sacral Hiatus During Caudal Epidural Injection Using Ultrasound Guidance. | OBJECTIVES: The aim of this study was to clarify differences in the anatomic structure of the sacral hiatus and angle of needle insertion during caudal epidural steroid injection using ultrasound guidance in patients according to sex and age.METHODS: A total of 237 patients with low back pain with or without sciatica w... | ['Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Anesthesia, Caudal', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Reproducibility of Results', 'Retrospective Studies', 'Sacrum', 'Sciatica', 'Sensitivity and Specificity', 'Sex Characteristics', 'Sex Distribution', 'Steroids', 'Treatment Outcome'... | 26,491,092 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E03.155.086.131.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Botulinum toxin restores presynaptic inhibition of group Ia afferents in patients with essential tremor. | We studied the effect of botulinum toxin A injection on the abnormal presynaptic phase of reciprocal inhibition between forearm antagonist muscles in patients with essential tremor. Ten patients with essential tremor were investigated before and 1 month after botulinum injection. Reciprocal inhibition was studied by co... | ['Adult', 'Aged', 'Aged, 80 and over', 'Botulinum Toxins, Type A', 'Electric Stimulation', 'Forearm', 'H-Reflex', 'Humans', 'Middle Aged', 'Neural Inhibition', 'Neuromuscular Agents', 'Neurons, Afferent', 'Presynaptic Terminals', 'Radial Nerve', 'Tremor'] | 9,843,072 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['E05.723.402'], ['A01.378.800.585'], ['G11.561.731.643.474'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Affinity chromatography of immobilized actin and myosin. | Actin and myosin were immobilized by coupling them to agarose matrices. Both immobilized G-actin and immobilized myosin retain most of the properties of the proteins in free solution and are reliable over long periods of time. Sepharose-F-actin, under the conditions used in this study, has proved unstable and variable ... | ['Actins', 'Adenosine Triphosphatases', 'Animals', 'Binding Sites', 'Chromatography, Affinity', 'Enzyme Activation', 'Hydrogen-Ion Concentration', 'Magnesium', 'Muscle Proteins', 'Muscles', 'Myosins', 'Papain', 'Potassium Chloride', 'Protein Binding', 'Rabbits', 'Sepharose'] | 241,335 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D08.811.277.040.025'], ['B01.050'], ['G02.111.570.120'], ['E05.196.181.400.170'], ['G02.111.263', 'G03.328'], ['G02.300'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D12.776.210.500'], ['A02.633', 'A10.690'], ['D05.750.078.730.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"I've also experienced loss and fear": Effects of prior similar experience on empathy. | Although it is frequently argued that empathy is increased by similar experiences, this idea has rarely been tested. This study investigated the relationship between empathy and prior similar experience. Participants read four different stories and rated the degree of empathy they felt. They also reported the extent to... | ['Adult', 'Age Factors', 'Empathy', 'Female', 'Humans', 'Life Change Events', 'Male', 'Multivariate Analysis', 'Regression Analysis', 'Sex Factors', 'Sweden'] | 18,705,672 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['N05.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Development of an immunoassay (ELISA) for the quantification of thiram in lettuce. | Two competitive immunoassays, a laboratory assay based on microwell plates and a field test based on the use of polystyrene tubes, have been developed for the quantification of thiram in lettuces. Concerning the laboratory assay, the calibration curve for thiram had a linear range of 11 to 90 ng/mL and a detection limi... | ['Enzyme-Linked Immunosorbent Assay', 'Fungicides, Industrial', 'Lettuce', 'Pesticide Residues', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Thiram', 'Time Factors'] | 11,308,309 | [['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D27.720.031.700.288', 'D27.888.723.288'], ['B01.650.940.800.575.912.250.100.500'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.32... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Management of chronic otitis media with effusion: the role of glutathione. | BACKGROUND: The inflammatory cells documented in chronic otitis media with effusion (OME) spontaneously release oxidants which can induce middle ear (ME) epithelial cell damage. Glutathione (GSH), a major extracellular antioxidant in humans, plays a central role in antioxidant defense.PURPOSE: To evaluate the effects o... | ['Child', 'Child, Preschool', 'Chronic Disease', 'Female', 'Glutathione', 'Humans', 'Male', 'Otitis Media with Effusion'] | 11,568,588 | [['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.500'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.705.663.670']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reduced alpha-2-antiplasmin levels in the nephrotic syndrome. | Venous and arterial thromboembolism frequently complicate the nephrotic syndrome. Increased platelet aggregation, high levels of fibrinogen and other procoagulants, and depressed levels of antithrombin III and plasminogen are commonly cited as reasons. Less attention has been paid to changes in the hemostatic system wh... | ['Antithrombin III', 'Hemostasis', 'Humans', 'Nephrotic Syndrome', 'Plasminogen', 'Platelet Factor 4', 'Serum Albumin', 'Thromboembolism', 'alpha-2-Antiplasmin', 'beta-Thromboglobulin'] | 3,157,072 | [['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.630.643', 'C13.351.968.419.630.643'], ['D08.622.610', 'D12.776.124.790.223.580', 'D12.776.377.715.182.580', 'D12.776.811.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wild birds and silage as reservoirs of Listeria in the agricultural environment. | A method for the isolation of listeria which enabled a more rapid detection of the organism was used to examine samples of silage and bird faeces. Faecal samples indicated that seagulls feeding at sewage works had a higher rate of carriage than those elsewhere. Faecal samples from rooks generally suggested a low incide... | ['Animal Feed', 'Animals', 'Birds', 'Disease Reservoirs', 'Feces', 'Hydrogen-Ion Concentration', 'Listeria', 'Listeria monocytogenes', 'Listeriosis', 'Seawater', 'Sewage', 'Sheep', 'Sheep Diseases', 'Silage'] | 3,938,452 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.248'], ['N06.850.520.203.250'], ['A12.459'], ['G02.300'], ['B03.353.500.500', 'B03.510.100.500', 'B03.510.460.400.410.485'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['C01.150.252.410.514'], ['G16.500.275.7... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mediator coordinates PIC assembly with recruitment of CHD1. | Murine Chd1 (chromodomain helicase DNA-binding protein 1), a chromodomain-containing chromatin remodeling protein, is necessary for embryonic stem (ES) cell pluripotency. Chd1 binds to nucleosomes trimethylated at histone 3 Lys 4 (H3K4me3) near the beginning of active genes but not to bivalent domains also containing H... | ['Animals', 'DNA Helicases', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'HeLa Cells', 'Histones', 'Humans', 'Immunoprecipitation', 'Mediator Complex', 'Mice', 'Protein Binding', 'Proteomics'] | 21,979,373 | [['B01.050'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D12.776.260'], ['G05.308'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.150.639', 'E05.478.605'], ['D05.500.374... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of 38 cases of employing aortic occlusion balloon catheter]. | BACKGROUND: Aortic occlusion balloon catheter (AOBC), which occludes the descending aorta without thoracotomy, is expected to prevent further blood loss and raise blood pressure (BP). We investigated the effects of AOBC retrospectively.METHOD: AOBC was used in 38 patients for perioperative management only if the BP res... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Aneurysm, Ruptured', 'Aorta', 'Balloon Occlusion', 'Blood Loss, Surgical', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Perioperative Care', 'Retrospective Studies', 'Shock, Hemorrhagic'] | 15,794,103 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.185'], ['A07.015.114.056'], ['E02.148.106', 'E02.520.392.500', 'E02.926.500.074', 'E05.157.063'], ['C23.550.414.300', 'C23.550.505.300'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evolution of wild-type and precore mutant HBV infection after liver transplantation. | Recurrence of hepatitis B virus (HBV) infection after liver transplantation is associated with varying degree of graft damage. The aim of the study was to investigate longitudinally the changes of wild-type and precore A1896HBV mutant viral populations after reinfection and their impact on liver graft damage. The wild-... | ['Adult', 'DNA, Viral', 'Evolution, Molecular', 'Female', 'Hepatitis B', 'Hepatitis B Core Antigens', 'Hepatitis B Surface Antigens', 'Hepatitis B e Antigens', 'Hepatitis B virus', 'Humans', 'Liver', 'Liver Transplantation', 'Male', 'Middle Aged', 'Mutation', 'Recurrence'] | 10,440,801 | [['M01.060.116'], ['D13.444.308.568'], ['G05.045.250', 'G16.075.250'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D23.050.327.495.500.450'], ['D23.050.327.495.500.475'], ['D23.050.327.495.500.469'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Heat shock protein 90 stabilizes nucleolin to increase mRNA stability in mitosis. | Most studies on heat shock protein 90 (Hsp90) have focused on the involvement of Hsp90 in the interphase, whereas the role of this protein in the nucleus during mitosis remains largely unclear. In this study, we found that the level of the acetylated form of Hsp90 decreased dramatically during mitosis, which indicates ... | ['Antibiotics, Antineoplastic', 'Benzoquinones', 'CDC2 Protein Kinase', 'Cell Nucleus', 'Chromatography, Liquid', 'HSP90 Heat-Shock Proteins', 'HeLa Cells', 'Humans', 'Immunoprecipitation', 'Lactams, Macrocyclic', 'Mass Spectrometry', 'Mitosis', 'Phosphoproteins', 'Protein Conformation', 'RNA', 'RNA Interference', 'RNA... | 21,998,300 | [['D27.505.954.248.106'], ['D02.806.250'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.776.744.360'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recombinant scFv antibodies against E protein and N protein of severe acute respiratory syndrome virus. | Three single chain antibodies (scFv) against the proteins of severe acute respiratory syndrome coronavirus (SARS-CoV) were isolated by phage display from an scFv antibody library. Bio-panning was carried out against immobilized purified envelope (E) and nucleocapsid (N) proteins of SARS-CoV. Their binding activity and ... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Viral', 'Antibody Affinity', 'Coronavirus Nucleocapsid Proteins', 'Gene Products, env', 'Immunoglobulin Fragments', 'In Vitro Techniques', 'Kinetics', 'Mice', 'Molecular Sequence Data', 'Nucleocapsid Proteins', 'Peptide Library', 'SARS Virus'] | 15,295,646 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G12.040', 'G12.122.125'], ['D12.776.964.970.600.700'], ['D12.776.775.320', 'D12.776.964.775.325', 'D12.776.964.970.880.325'], ['D12.644.541.500', 'D12.776.124.486.48... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Histone methylation in the freeze-tolerant wood frog (Rana sylvatica). | Freeze-tolerant animals survive sub-zero temperatures and long-term starvation associated with the winter by lowering their metabolic rate using a variety of transcriptional, translational, and post-translational regulatory methods. Histone methylation is one mechanism that is known to regulate gene expression at the t... | ['Acclimatization', 'Animals', 'Freezing', 'Histone Methyltransferases', 'Histones', 'Liver', 'Male', 'Methylation', 'Muscle, Skeletal', 'Ranidae', 'Reptilian Proteins'] | 28,601,897 | [['G07.025.133', 'G16.012.500.133'], ['B01.050'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['D08.811.913.555.500.800.200'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['A03.620'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['A02.633.567', 'A10.690.552.500'], ['B01.050.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of ZnO addition on bioactive CaO-SiO2-P2O5-CaF2 glass-ceramics containing apatite and wollastonite. | Some ceramics show bone-bonding ability, i.e. bioactivity. Apatite formation on ceramics is an essential condition to bring about direct bonding to living bone when implanted into bony defects. A controlled surface reaction of the ceramic is an important factor governing the bioactivity and biodegradation of the implan... | ['Apatites', 'Biocompatible Materials', 'Body Fluids', 'Calcium Compounds', 'Ceramics', 'Computer Simulation', 'Mechanics', 'Microscopy, Electron, Scanning', 'Resin Cements', 'Silicates', 'Temperature', 'Zinc Oxide'] | 16,765,885 | [['D01.029.260.700.675.374.075.025', 'D01.146.360.050', 'D01.578.122', 'D01.695.625.675.650.075.025'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A12.207'], ['D01.146'], ['J01.637.153'], ['L01.224.160'], ['H01.671.515'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D05.750.716.822.730', 'D25.339.291.750'... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Volatile anaesthetics inhibit a cyclic AMP-dependent sodium-potassium current in cultured sensory neurones of bullfrog. | 1. Cultured dorsal root ganglion cells of the bullfrog were voltage-clamped in the whole-cell configuration. 2. An adenosine 3':5'-cyclic monophosphate (cyclic AMP)-dependent cationic inward rectifier (IH) was inhibited by bath application of enflurane (0.2-0.8 mM) and halothane (0.2-0.5 mM), which thereby induced an o... | ['Anesthetics', 'Animals', 'Cells, Cultured', 'Colforsin', 'Cyclic AMP', 'Depression, Chemical', 'Enflurane', 'Halothane', 'In Vitro Techniques', 'Membrane Potentials', 'Neurons, Afferent', 'Potassium Channels', 'Rana catesbeiana', 'Sodium Channels'] | 2,178,015 | [['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['B01.050'], ['A11.251'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['G07.690.773.750'], ['D02.355.601.400'], ['D02.455.526.340'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability. | The development of resistance to paclitaxel in tumors is one of the most significant obstacles to successful therapy. Overexpression of the betaIII-tubulin isotype has been associated with paclitaxel resistance in a number of cancer cell lines and in tumors, but the mechanism of resistance has remained unclear. Paclita... | ['Animals', 'Antineoplastic Agents, Phytogenic', 'CHO Cells', 'Cell Proliferation', 'Cells, Cultured', 'Cricetinae', 'Dose-Response Relationship, Drug', 'Drug Resistance, Neoplasm', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'Microscopy, Fluorescence', 'Microtubules', 'Mitosis', 'Paclitaxel', 'Prote... | 15,695,826 | [['B01.050'], ['D27.505.954.248.179'], ['A11.251.210.200', 'A11.436.155'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984.395'], ['L01.224.308'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Impact of abomasal nematodes on roe deer and chamois body condition in an alpine environment. | Abomasal helminths were examined from 101 roe deer and 43 chamois, shot or found-dead, in the period July-November 1993-95, in the Parco Naturale Paneveggio Pale di San Martino (Italian Eastern Alps). Twelve helminth species were observed in both roe deer and chamois. For both host species, discriminant analysis, using... | ['Abomasum', 'Animals', 'Biometry', 'Cold Climate', 'Deer', 'Disease Reservoirs', 'Female', 'Goat Diseases', 'Goats', 'Health Status', 'Helminthiasis, Animal', 'Italy', 'Male', 'Prevalence', 'Sheep', 'Sheep Diseases', 'Species Specificity', 'Stomach Diseases'] | 9,802,085 | [['A13.869.106'], ['B01.050'], ['E05.318.740.225', 'N06.850.505.200'], ['G16.500.275.071.275', 'N06.230.300.100.250.275'], ['B01.050.150.900.649.313.500.380.373'], ['N06.850.520.203.250'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['C01.610.335.349', 'C... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Alcohol intake and ethanol intoxication in the rate: effect of a 6-OHDA-induced lesion of the ascending noradrenaline pathways. | The ascending noradrenaline (NA) pathways were lesioned by injecting 6-hydroxydopamine (6-OHDA) 16 micrograms/4 microliters bilaterally into the posterior mesencephalon in male Long Evans rats. Another group of rats was pretreated with protriptyline (25 mg/kg), a NA uptake blocking agent, 15 min before they received th... | ['Alcohol Drinking', 'Alcoholic Intoxication', 'Animals', 'Body Temperature', 'Dopamine', 'Humans', 'Hydroxydopamines', 'Male', 'Neural Pathways', 'Norepinephrine', 'Rats', 'Sleep'] | 7,192,632 | [['F01.145.317.269'], ['C25.775.100.175', 'F03.900.100.300'], ['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.311.342.478', 'D02.455.426.559.389.657.166.175.342.478'], ['A08.612... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Topology of repeated sequences: relationship of nuclear RNA to the repeated sequences of the main and satellite DNA in mouse plasmocytoma cells. | The topology of repeated sequences in mouse plasmocytoma DNA was studied by high-resolution CsCl density gradient centrifugation and heterogeneous nuclear RNA.DNA hybridization. Satellite region DNA of plasmocytoma cells contains additional components and hybridizes specifically with entire heterogeneous nuclear RNA mo... | ['Animals', 'Base Sequence', 'Cell Fractionation', 'Cell Nucleus', 'Cells, Cultured', 'Centrifugation, Density Gradient', 'DNA, Neoplasm', 'Electrophoresis', 'Genetic Linkage', 'Mice', 'Mice, Inbred BALB C', 'Molecular Weight', 'Neoplasms, Experimental', 'Nucleic Acid Hybridization', 'Plasmacytoma', 'RNA, Neoplasm'] | 4,530,326 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.242.251'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['E05.181.724.336', 'E05.196.941.336'], ['D13.444.308.425'], ['E05.196.401', 'E05.301.300'], ['G05.348'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Systemic and uterine hemodynamic responses to dopamine in pregnant and nonpregnant sheep. | The systemic and uterine hemodynamic effects of dopamine were studied in nonpregnant and near-term pregnant, unanesthetized, chronically instrumented sheep. Dopamine was administered by constant intravenous infusion in doses ranging from 2 to 40 microgram per kilogram per minute. A hypertensive effect was consistently ... | ['Animals', 'Blood Pressure', 'Cardiac Output', 'Dopamine', 'Female', 'Heart Rate', 'Hemodynamics', 'Pregnancy', 'Pregnancy, Animal', 'Regional Blood Flow', 'Sheep', 'Uterus', 'Vascular Resistance'] | 637,082 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.150', 'G09.330.380.124'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['G08.686.784.769'], ['G08.686.784.769.498'], ['G09.330.100.780'], ['B01.0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Establishment and application of pollutant discharge-environment quality model]. | In order to explore the mutual influence between pollutant discharge and environment quality, relation models of pollutant discharge and environmental quality were established, and the relationship was divided into four types, low pollutant discharge-high environmental quality, high pollutant discharge-high environment... | ['China', 'Environmental Pollution', 'Models, Theoretical'] | 24,881,417 | [['Z01.252.474.164'], ['N06.850.460'], ['E05.599']] | ['Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Epileptic seizures in children caused by developmental anomalies of meningocerebral vessels]. | In the light of pertinent literature the authors discuss two interesting cases of developmental anomalies of cerebral vessels demonstrated by means of angiography which were the cause of epileptic seizures and progressive dementia. | ['Adolescent', 'Age Factors', 'Arteriovenous Malformations', 'Brain', 'Cerebral Angiography', 'Child', 'Epilepsy', 'Female', 'Humans', 'Male', 'Meninges'] | 1,202,406 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['A08.186.211'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['M01.060.406'], ['C10.228.140.490... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fungal polyketide synthase product chain-length control by partnering thiohydrolase. | Fungal highly reducing polyketide synthases (HRPKSs) are an enigmatic group of multidomain enzymes that catalyze the biosynthesis of structurally diverse compounds. This variety stems from their intrinsic programming rules, which permutate the use of tailoring domains and determine the overall number of iterative cycle... | ['Anti-Infective Agents', 'Brefeldin A', 'Cloning, Molecular', 'Eupenicillium', 'Genome, Fungal', 'Hydrolases', 'Molecular Sequence Data', 'Multigene Family', 'Polyketide Synthases', 'Saccharomyces cerevisiae', 'Transcriptome'] | 24,845,309 | [['D27.505.954.122'], ['D02.540.576.500.875'], ['E05.393.220'], ['B01.300.107.320.215'], ['G05.360.340.358.365'], ['D08.811.277'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['D08.811.464.257.275', 'D08.811.600.715'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['G02.111.873.750', 'G05.297.700.750', 'G05... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Strong allergic patch test reactions may indicate a general disposition for contact allergy. | BACKGROUND: Patch test patients have two or more positive reactions to unrelated allergens more often than to be expected by chance. This study evaluates synchronous patch test reactions to test the hypothesis that in such cases an allergen-independent disposition for contact sensitization may be involved.METHODS: Data... | ['Adolescent', 'Adult', 'Age Distribution', 'Allergens', 'Dermatitis, Allergic Contact', 'Disease Susceptibility', 'Female', 'Follow-Up Studies', 'Germany', 'Humans', 'Hypersensitivity, Immediate', 'Male', 'Middle Aged', 'Nickel', 'Patch Tests', 'Perfume', 'Prevalence', 'Registries', 'Retrospective Studies', 'Risk Asse... | 16,436,147 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['D23.050.063'], ['C17.800.174.255.100', 'C17.800.815.255.100', 'C20.543.418.150'], ['C23.550.291.687', 'G07.100.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Membrane-based, dry-reagent prothrombin time tests. | The authors describe a prototype membrane-based, dry-reagent prothrombin time assay for whole blood. This system uses an asymmetric polysulfone membrane to separate plasma from red blood cells, and works with samples as small as 10 microliters. The membrane contains calcium and thromboplastin, and permits the reactions... | ['Anticoagulants', 'Biocompatible Materials', 'Blood Coagulation', 'Calcium', 'Erythrocytes', 'Fluorescence', 'Fluorescent Dyes', 'Humans', 'Indicators and Reagents', 'Membranes, Artificial', 'Plasma', 'Polymers', 'Prothrombin Time', 'Rhodamines', 'Sulfones', 'Thrombin', 'Thromboplastin', 'Warfarin'] | 8,739,001 | [['D27.505.954.502.119'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G09.188.390.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Metabolism of cryptic peptides derived from neuropeptide FF precursors: the involvement of insulin-degrading enzyme. | The term "cryptome" refers to the subset of cryptic peptides with bioactivities that are often unpredictable and very different from the parent protein. These cryptic peptides are generated by proteolytic cleavage of proteases, whose identification in vivo can be very challenging. In this work, we show that insulin-deg... | ['Amino Acid Sequence', 'Animals', 'Cerebral Cortex', 'Insulysin', 'Male', 'Mass Spectrometry', 'Models, Biological', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Peptide Fragments', 'Protein Precursors', 'Proteolysis', 'Rats', 'Rats, Wistar', 'Receptors, Neuropeptide', 'Spectrometry, Mass, Electrospray Ionizat... | 25,247,577 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['D08.811.277.656.300.480.300', 'D08.811.277.656.675.374.300'], ['E05.196.566'], ['E05.599.395'], ['L01.453.245.667'], ['D12.776.631'], ['D12.644.541'], ['D12.776.811'], ['G02.111.720', 'G03.812'], ['B01.050.150.900.649.313.992.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of irradiation on cytokine production in glioma cell lines. | The effects of irradiation on cytokine production in glioma cell lines, NP1, NP2 and NP3, were studied. Culture supernatants were collected after 6, 24, 48 or 72 hours and the concentrations of interleukin (IL)-6 and IL-8 measured by enzyme-linked immunosorbent assay. Spontaneous and IL-1 beta-stimulated productions we... | ['Glioma', 'Humans', 'Interleukin-1', 'Interleukin-6', 'Interleukin-8', 'Radiation Effects', 'Tumor Cells, Cultured'] | 7,506,809 | [['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D12.644.276.374.465.224', 'D12.77... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Unusual cause of dysuria: migration of a pacemaker generator into the urinary bladder. | Following pacemaker implantation, a 71-year-old female developed infection of the generator pocket. Five years after relocation posterior to the rectus muscle she suffered from cystitis. Cystoscopy revealed the pacemaker generator to be lying within the urinary bladder. Healing was achieved by removing the pacemaker an... | ['Aged', 'Cystitis', 'Female', 'Foreign Bodies', 'Foreign-Body Migration', 'Humans', 'Pacemaker, Artificial', 'Urinary Bladder', 'Urination Disorders'] | 1,695,347 | [['M01.060.116.100'], ['C12.777.829.495', 'C13.351.968.829.495'], ['C26.392'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.750'], ['A05.810.890'], ['C12.777.934', 'C13.351.968.934']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of magnetic coil orientation on the excitation of the median nerve. | OBJECTIVE: We investigated the effect of magnetic coil orientation on the excitation of the median nerve in healthy subjects.METHODS: An 8-shaped coil, 3.2 cm in outer diameter, was used. The median nerve was stimulated at the elbow while the compound muscle action potentials (CMAPs) of abductor pollicis brevis muscle ... | ['Action Potentials', 'Adult', 'Analysis of Variance', 'Arm', 'Electric Conductivity', 'Electric Stimulation', 'Electromagnetic Fields', 'Female', 'Humans', 'Male', 'Median Nerve', 'Models, Neurological', 'Neural Conduction', 'Physical Stimulation'] | 9,613,564 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A01.378.800.075'], ['G01.358.500.249.277'], ['E05.723.402'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.500'],... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antinociceptive and anti-inflammatory activity of the ethanolic extract of Cymbidium aloifolium (L.). | The ethanol leaf extract of Cymbidium aloifolium (L.) was evaluated for its analgesic and antiinflammatory activities. The extract, at the dose of 200 and 400 mg kg(-1) body weight, exerted the analgesic activity by observing the number of abdominal contractions and anti-inflammatory activity against Carrageenin induce... | ['Acetic Acid', 'Analgesics', 'Animals', 'Anti-Inflammatory Agents', 'Carrageenan', 'Edema', 'Ethanol', 'Female', 'Male', 'Mice', 'Pain Measurement', 'Plant Extracts', 'Plant Leaves'] | 22,518,936 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.954.158'], ['D09.698.152'], ['C23.888.277'], ['D02.033.375'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.600.550.324'], ['D20.215.784.500', 'D26.667'], ['A18.024.812']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lingual lipase. Its role in lipid digestion in infants with low birthweight and/or pancreatic insufficiency. | At birth both pancreatic lipase and carboxylic ester hydrolase, two important lipolytic enzymes secreted by the pancreas, are present in duodenal contents but the activities of these enzymes are low. Another enzyme of possible importance in lipolysis is the lingual lipase which is secreted from serous glands present at... | ['Bile Acids and Salts', 'Cystic Fibrosis', 'Dietary Fats', 'Exocrine Pancreatic Insufficiency', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Intestinal Absorption', 'Lipase', 'Lipid Metabolism', 'Milk, Human', 'Pancreas', 'Stomach', 'Tongue'] | 6,961,751 | [['D04.210.500.105'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['C06.689.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500',... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Early initiation and regular breast milk expression reduces risk of lactogenesis II delay in at-risk Singaporean mothers in a randomised trial. | INTRODUCTION: Lactogenesis II (LaII) failure can be prevented in at-risk mothers with simple proactive interventions. In a randomised trial, we investigated the efficacy of early and regular breast milk expression in establishing LaII, using an electric double-breast pump.METHODS: Mothers with uncomplicated singleton d... | ['Adult', 'Breast Feeding', 'Breast Milk Expression', 'Citrates', 'Female', 'Humans', 'Infant Formula', 'Infant, Newborn', 'Lactation', 'Milk, Human', 'Mothers', 'Proteins', 'Sodium', 'Young Adult'] | 29,876,577 | [['M01.060.116'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['F01.145.407.199.500', 'G07.203.650.220.500.500.500', 'G07.203.650.353.199.500'], ['D02.241.081.901.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.100.712.249', 'G07.203.300.525.350.500', 'G07... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
Development of novel tricalcium silicate-based endodontic cements with sintered radiopacifier phase. | OBJECTIVES: All implants, bone and endodontic cements need to be sufficiently radiopaque to be able to be distinguished from neighbouring anatomical structures post-operatively. For this purpose, radiopacifying materials are added to the cements to render them sufficiently radiopaque. Bismuth oxide has been quite a pop... | ['Aluminum Compounds', 'Barium', 'Calcium', 'Calcium Compounds', 'Compressive Strength', 'Dental Cements', 'Drug Combinations', 'Hydrogen-Ion Concentration', 'Microscopy, Electron, Scanning', 'Oxides', 'Porosity', 'Silicates', 'Strontium', 'Surface Properties', 'X-Ray Diffraction', 'Zirconium'] | 26,323,502 | [['D01.056'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.146'], ['G01.374.180'], ['D25.339.291', 'J01.637.051.339.291'], ['D26.310'], ['G02.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.248.497.158.685', 'D01.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Chemopreventive effects of S-methylcysteine on rat hepatocarcinogenesis induced by concurrent administration of sodium nitrite and morpholine. | The aim of the present study was to examine the chemopreventive efficacy of S-methylcysteine (SMC) on rat hepatocarcinogenesis induced by concurrent administration of sodium nitrite (NaNO(2)) and morpholine (Mor) using a medium-term rat liver carcinogenesis bioassay (Ito test). Administration of SMC caused significant ... | ['Animals', 'Anticarcinogenic Agents', 'Body Weight', 'Bromodeoxyuridine', 'Carcinogens', 'Cell Division', 'Cysteine', 'Drug Interactions', 'Food Preservatives', 'Gastric Mucosa', 'Glutathione Transferase', 'Liver', 'Liver Neoplasms, Experimental', 'Male', 'Morpholines', 'Nitrosamines', 'Precancerous Conditions', 'Rats... | 11,078,918 | [['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['D27.888.569.100'], ['G04.144.220', 'G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Hyperparathyroidism following irradiation of benign diseases of the head and neck. | In a series of 73 consecutive patients with hyperparathyroidism (HPT) eight patients gave a history of irradiation of head and neck because of benign diseases. The average interval between irradiation and definite diagnosis was 34 years. Intermittent hypercalcaemia was found in three patients. Microscopic examination o... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Follow-Up Studies', 'Head', 'Humans', 'Hyperparathyroidism', 'Male', 'Middle Aged', 'Neck', 'Radiotherapy', 'Thyroid Function Tests', 'Time Factors'] | 6,861,085 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355'], ['M01.060.116.630'], ['A01.598'], ['E02.815'], ['E01.370.374.750'], ['G01.910... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Desensitization to 5-fluorouracil. | Anaphylactic reactions to 5-fluorouracil (5-FU) are uncommon. We report a 40-year-old female with adenocarcinoma of the ovary who had two reactions immediately after being infused with 5-FU. The second reaction occurred despite prophylaxis with steroids and antihistamines. The patient was positive to 5-FU on puncture s... | ['Adenocarcinoma', 'Adult', 'Anaphylaxis', 'Antimetabolites, Antineoplastic', 'Desensitization, Immunologic', 'Female', 'Fluorouracil', 'Humans', 'Immunoglobulin E', 'Infusions, Intravenous', 'Ovarian Neoplasms', 'Skin Tests'] | 10,389,552 | [['C04.557.470.200.025'], ['M01.060.116'], ['C20.543.480.099'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['E02.095.465.425.450.310', 'E05.478.610.310'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.11... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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