Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Efficacy and safety of tanezumab added on to diclofenac sustained release in patients with knee or hip osteoarthritis: a double-blind, placebo-controlled, parallel-group, multicentre phase III randomised clinical trial. | OBJECTIVES: Tanezumab, a monoclonal antibody, inhibits nerve growth factor and reduces chronic pain. This randomised, double-blind, controlled multicentre study was conducted to evaluate the efficacy and safety of tanezumab added to oral diclofenac sustained release (DSR) in patients with hip or knee osteoarthritis (OA... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antibodies, Monoclonal, Humanized', 'Delayed-Action Preparations', 'Diclofenac', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Drug Therapy, Combination', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis, Hip', 'O... | 23,852,695 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.223.601.210'], ['G07... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Carcinomesenchymoma of the uterus. | A unique case of intramural uterine tumor composed of malignant epithelium and benign smooth muscle, adipose tissue, and cartilage is reported. This tumor, which the authors designated "carcinomesenchymoma," apparently represents an example of a previously unreported variant of mixed m?llerian tumor that is composed of... | ['Carcinoma', 'Endometriosis', 'Epithelium', 'Female', 'Humans', 'Mesenchymoma', 'Middle Aged', 'Uterine Neoplasms'] | 7,234,760 | [['C04.557.470.200'], ['C13.351.500.163'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.435.500'], ['M01.060.116.630'], ['C04.588.945.418.948', 'C13.351.500.852.762', 'C13.351.937.418.875']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Imaging and treatment of B-cell lymphoma. | Ten patients with non-Hodgkin's lymphoma have been evaluated as candidates for experimental radioimmunotherapy and five of those patients have been treated with a single high dose of iodine-131-(131I) labeled anti-pan B-cell antibodies. The evaluation protocol involved collecting biodistribution data by quantitation of... | ['Antibodies, Monoclonal', 'B-Lymphocytes', 'Combined Modality Therapy', 'Humans', 'Immunotherapy', 'Iodine Radioisotopes', 'Lymphoma, Non-Hodgkin', 'Radionuclide Imaging', 'Tissue Distribution'] | 2,384,792 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['D01.268.380.400.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wave action modifies the effects of consumer diversity and warming on algal assemblages. | To understand the consequences of biodiversity loss, it is necessary to test how biodiversity-ecosystem functioning relationships may vary with predicted environmental change. In particular, our understanding will be advanced by studies addressing the interactive effects of multiple stressors on the role of biodiversit... | ['Animals', 'Biodiversity', 'Food Chain', 'Global Warming', 'Herbivory', 'Seaweed', 'Water Movements'] | 26,230,022 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['G16.500.275.157.250', 'N06.230.124.250'], ['G16.500.175.374.500'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['B05.080.750'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Zinc oxide inverse opal electrodes modified by glucose oxidase for electrochemical and photoelectrochemical biosensor. | The ZnO inverse opal photonic crystals (IOPCs) were synthesized by the sol-gel method using the polymethylmethacrylate (PMMA) as a template. For glucose detection, glucose oxidase (GOD) was further immobilized on the inwall and surface of the IOPCs. The biosensing properties toward glucose of the Nafion/GOD/ZnO IOPCs m... | ['Biosensing Techniques', 'Electrochemical Techniques', 'Electrodes', 'Enzymes, Immobilized', 'Equipment Design', 'Fluorocarbon Polymers', 'Glucose', 'Glucose Oxidase', 'Limit of Detection', 'Photochemical Processes', 'Reproducibility of Results', 'Zinc Oxide'] | 24,752,145 | [['E05.601.043'], ['E05.301'], ['E07.305.250'], ['D08.811.180', 'D12.776.463.500'], ['E05.320'], ['D05.750.395', 'D25.720.395', 'J01.637.051.720.395'], ['D09.947.875.359.448'], ['D08.811.682.047.239'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G02.740'], ['E05.318.370.725', 'E05.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
In vivo and in vitro NMR spectroscopy reveal a putative novel inborn error involving polyol metabolism. | In vivo NMR spectroscopy was performed on the brain of a patient with a leukoencephalopathy, revealing unknown resonances between 3.5 and 4.0 ppm. In addition, urine and CSF of the patient were measured using high-resolution NMR spectroscopy. Also in these in vitro spectra, unknown resonances were observed in the 3.5-4... | ['Adolescent', 'Brain Diseases', 'Carbohydrate Metabolism, Inborn Errors', 'Cerebrospinal Fluid', 'Chromatography, Gas', 'Humans', 'Magnetic Resonance Spectroscopy', 'Male', 'Parietal Lobe', 'Ribitol', 'Sugar Alcohols'] | 11,357,181 | [['M01.060.057'], ['C10.228.140'], ['C16.320.565.202', 'C18.452.648.202'], ['A12.207.270.210'], ['E05.196.181.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['A08.186.211.200.885.287.500.670'], ['D02.033.800.780', 'D09.853.780'], ['D02.033.800', 'D09.853']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The nucleus retroambigualis controls laryngeal muscle activity during vocalization in the cat. | The purpose of this study was to determine (1) whether the nucleus retroambigualis (NRA) plays an essential role in periaqueductal gray (PAG)-induced vocalization and (2) which NRA neurons are involved in the projection from the PAG to laryngeal motoneurons. Bilateral injections of the neurotoxin kainic acid into the N... | ['Action Potentials', 'Animals', 'Brain Mapping', 'Brain Stem', 'Cats', 'Female', 'Kainic Acid', 'Laryngeal Muscles', 'Male', 'Motor Neurons', 'Movement', 'Periaqueductal Gray', 'Respiratory Center', 'Vocalization, Animal'] | 9,262,206 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D03.383.773.400'], ['A02.633.567.500', 'A04.329.604'], ['A08.675.655.500', 'A11.671.655.500'], ['G07.568... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The nocebo effect during oral challenge in subjects with adverse drug reactions. | BACKGROUND: Nocebo effect is the occurrence of troublesome symptoms after the administration of inert substances. It can be easily studied during blind oral challenges for drug reactions, which always involve the administration ofa placebo.METHODS: We collected data about nocebo effect in outpatients undergoing oral dr... | ['Abdominal Pain', 'Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Allergens', 'Angioedema', 'Anxiety', 'Depression', 'Female', 'Humans', 'Hypersensitivity', 'Immunization', 'Male', 'Middle Aged', 'Placebo Effect', 'Pruritus', 'Respiratory Sounds', 'Sex Factors', 'Surveys and Questionnaires', 'Talc', 'Urticaria... | 19,227,649 | [['C23.888.592.612.054', 'C23.888.821.030'], ['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.050.063'], ['C14.907.079', 'C17.800.862.945.066', 'C20.543.480.904.066'], ['F01.470.132'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E02.095.465.425.4... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acetate provokes mitochondrial stress and cell death in Ustilago maydis. | The fungal pathogen Ustilago maydis causes disease on maize by mating to establish an infectious filamentous cell type that invades the host and induces tumours. We previously found that â-oxidation mutants were defective in virulence and did not grow on acetate. Here, we demonstrate that acetate inhibits filamentation... | ['Acetates', 'Cell Death', 'Diclofenac', 'Glucose', 'Mitochondria', 'Mutation', 'Oleic Acid', 'Plant Diseases', 'Reactive Oxygen Species', 'Transcriptome', 'Ustilago', 'Virulence', 'Zea mays'] | 29,235,175 | [['D02.241.081.018', 'D10.251.400.045'], ['G04.146'], ['D02.241.223.601.210'], ['D09.947.875.359.448'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.365.590'], ['D10.251.355.325.600.525'], ['G15.610'], ['D01.339.431', 'D01.650.775'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920'], ['B01.300.179.853.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Duration of intubation and ICU stay after open heart surgery. | One hundred four consecutive patients undergoing open heart surgery were studied to determine the duration of intubation and ICU stay associated with an anesthetic management protocol designed to avoid prolonged postoperative respiratory depression. The results document the feasibility and safety of early extubation an... | ['Adult', 'Cardiac Surgical Procedures', 'Child', 'Heart-Lung Machine', 'Humans', 'Intensive Care Units', 'Intubation', 'Postoperative Care', 'Postoperative Period', 'Time Factors'] | 451,679 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are DNA ploidy and epidermal growth factor receptor prognostic factors for untreated ovarian cancer? A prospective study. | To identify prognostic factors for untreated ovarian cancer, DNA ploidy, proliferative index (P.I.) and epidermal growth factor receptor (EGFR) expression were analyzed in a prospective series of 40 patients with ovarian cancer and 7 patients with borderline malignant ovarian tumor followed up for 5 years or more (medi... | ['ErbB Receptors', 'Female', 'Humans', 'Multivariate Analysis', 'Ovarian Neoplasms', 'Ploidies', 'Prognosis', 'Prospective Studies', 'Survival Rate'] | 11,404,488 | [['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.39... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ischemic pathology of the colon. | Ischemic colitis is a disease with a polymorphic clinical picture, which may be of a formidable gravity in gangrenous forms. Its etiologies are varied and more and more due to a low arterial output. The examinations permitting to establish the diagnosis are barium enema and mostly colonoscopy which should be performed ... | ['Colon', 'Constriction, Pathologic', 'Diagnosis, Differential', 'Gangrene', 'Humans', 'Ischemia'] | 3,813,475 | [['A03.556.124.526.356', 'A03.556.249.249.356'], ['C23.300.287'], ['E01.171'], ['C23.550.717.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513']] | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystal structure and functional analysis of the histone methyltransferase SET7/9. | Methylation of lysine residues in the N-terminal tails of histones is thought to represent an important component of the mechanism that regulates chromatin structure. The evolutionarily conserved SET domain occurs in most proteins known to possess histone lysine methyltransferase activity. We present here the crystal s... | ['Amino Acid Sequence', 'Binding Sites', 'Catalysis', 'Catalytic Domain', 'Circular Dichroism', 'Crystallography, X-Ray', 'DNA Methylation', 'DNA Mutational Analysis', 'DNA-Binding Proteins', 'Drosophila Proteins', 'Escherichia coli', 'Histone Methyltransferases', 'Histone-Lysine N-Methyltransferase', 'Histones', 'Huma... | 12,372,304 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['G02.130'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.867.151'], ['E05.196.309.742.225'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['E05.393.760.700.300'], ['D12.776.260'], ['D12.776.093.500.462']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
New approaches for enhanced detection of enteroviruses from Hawaiian environmental waters. | Health risks associated with sewage-contaminated recreational waters are of important public health concern. Reliable water monitoring systems are therefore crucial. Current recreational water quality criteria rely predominantly on the enumeration of bacterial indicators, while potentially dangerous viral pathogens oft... | ['Animals', 'Enterovirus', 'Environmental Monitoring', 'Feces', 'Hawaii', 'Humans', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sewage', 'Shellfish', 'Water Microbiology'] | 22,567,083 | [['B01.050'], ['B04.820.578.750.284'], ['N06.850.460.350.080', 'N06.850.780.375'], ['A12.459'], ['Z01.107.567.875.580.375', 'Z01.639.760.815.482'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500.725'], ['D20.944.932.500'], ['G07.203.300.600.875.700', 'J02.500.600.875.700'], ['H01.158.273.540.274.777... | ['Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Associated with Ischemic Stroke Risk Reduction after Endoscopic Thoracic Sympathectomy for Palmar Sweating. | BACKGROUND: Endoscopic thoracic sympathectomy (ETS) was performed to cure palmar hyperhidrosis (PH). After ETS, blood pressure decreased, and cerebral flow velocity increased within 1 month. However, no studies distinguish between subsequent ischemic and hemorrhagic stroke following ETS for PH. The association between ... | ['Adolescent', 'Adult', 'Brain Ischemia', 'Cerebral Hemorrhage', 'Endoscopy', 'Female', 'Hand', 'Humans', 'Hyperhidrosis', 'Incidence', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Postoperative Complications', 'Proportional Hazards Models', 'Risk Factors', 'Stroke', 'Sympathectomy', 'Young ... | 29,784,606 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E01.370.388.250', 'E04.502.250'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.946.350'], ['E05.318.308.985.525.375', 'N01.224.93... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Linear System Models for Ultrasonic Imaging: Intensity Signal Statistics. | Despite a great deal of work characterizing the statistical properties of radio frequency backscattered ultrasound signals, less is known about the statistical properties of demodulated intensity signals. Analysis of intensity is made more difficult by a strong nonlinearity that arises in the process of demodulation. T... | ['Computer Simulation', 'Image Processing, Computer-Assisted', 'Linear Models', 'Phantoms, Imaging', 'Signal Processing, Computer-Assisted', 'Ultrasonography'] | 28,092,533 | [['L01.224.160'], ['L01.224.308'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E07.671'], ['L01.224.800'], ['E01.370.350.850']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Comparison of neutral and positive enteral contrast media for MDCT enteroclysis. | OBJECTIVE: To compare neutral and positive enteral contrast media for MDCT enteroclysis (MDCTE) in various small bowel diseases.MATERIALS AND METHODS: 40 patients with suspicion of small bowel diseases were divided randomly into two equal groups. In one group, water was used as neutral enteral contrast and in other gro... | ['Adolescent', 'Adult', 'Biopsy', 'Chi-Square Distribution', 'Contrast Media', 'Diagnosis, Differential', 'Endoscopy, Gastrointestinal', 'Female', 'Humans', 'Intestinal Diseases', 'Intestine, Small', 'Iohexol', 'Male', 'Middle Aged', 'Multidetector Computed Tomography', 'Predictive Value of Tests', 'Sensitivity and Spe... | 21,239,131 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of dietary fat on rat liver microsomal and mitochondrial/lysosomal dolichol, phospholipid and cholesterol. | The influence of different fat diets on liver phospholipid, cholesterol and dolichol was studied. Rats were separated into four groups and fed standard laboratory chow (control), a diet containing linolenic acid, a coconut oil diet, or a corn oil-containing diet. After five weeks, microsomes and mitochondrial/lysosomal... | ['Animals', 'Cholesterol', 'Coconut Oil', 'Corn Oil', 'Dietary Fats', 'Dolichols', 'Fatty Acids', 'Linolenic Acids', 'Lipids', 'Liver', 'Lysosomes', 'Male', 'Microsomes', 'Mitochondria', 'Phospholipids', 'Plant Oils', 'Rats', 'Rats, Inbred Strains', 'Subcellular Fractions'] | 1,805,096 | [['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10.627.700.186'], ['D10.212.302.380.370', 'D10.212.507.340', 'D10.627.700.240', 'D20.215.784.750.240', 'G07.203.300.375.400.250', 'J02.500.375.400.250'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D02.033.318', 'D02.03... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Generation and characterization of JCV permissive hybrid cell lines. | JC virus (JCV) is a human neurotropic polyomavirus whose replication in the central nervous system induces the fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML). JCV particles have been detected primarily in oligodendrocytes and astrocytes of the brains of patients with PML and in the labora... | ['Cell Fusion', 'Cell Line', 'DNA, Viral', 'Humans', 'Hybrid Cells', 'JC Virus', 'Leukoencephalopathy, Progressive Multifocal', 'Virus Replication'] | 19,442,856 | [['E05.242.307', 'G04.155'], ['A11.251.210'], ['D13.444.308.568'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.600'], ['B04.280.210.700.615.400', 'B04.613.204.670.615.400'], ['C01.207.245.340.500', 'C01.207.399.750.500', 'C01.925.182.525.500', 'C01.925.256.721.500', 'C01.925.839.550', 'C10.228.140.430.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Syphilis mimicking idiopathic intracranial hypertension. | Idiopathic intracranial hypertension (IIH) is a condition of yet unknown aetiology affecting predominantly obese females of childbearing age. IIH is a diagnosis of exclusion as raised cerebrospinal fluid pressure may occur secondary to numerous other medical conditions. An atypical phenotype or an atypical disease cour... | ['Adult', 'Brain Diseases', 'Diagnosis, Differential', 'Humans', 'Male', 'Neurosyphilis', 'Pseudotumor Cerebri'] | 22,674,114 | [['M01.060.116'], ['C10.228.140'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.223.600', 'C01.150.252.400.794.840.500.750', 'C01.150.252.400.840.500.750', 'C01.207.180.600', 'C10.228.228.180.600'], ['C10.228.140.631.750']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lethal male combats in Schizotetranychus brevisetosus (Acari: Tetranychidae) on blue Japanese oak (Quercus glauca). | Male spider mites (Acari: Tetranychidae) guard preimaginal quiescent females to reserve paternity. In a few species of Stigmaeopsis that make densely woven silky nests on the surface of host plants, mature males attack and even kill rivals to gain their rights to inseminate young females in the nest. Here we report tha... | ['Aggression', 'Animals', 'Body Size', 'Male', 'Quercus', 'Tetranychidae'] | 26,122,967 | [['F01.145.126.125', 'F01.145.813.045'], ['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['B01.050.500.131.166.132.419.850']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of serum on the secretion of radiolabeled mucous macromolecules into the lumen of the cat trachea. | We studied the effect of placing serum within a segment of trachea on secretion into its lumen in the cat. A segment of cervical trachea was isolated from the rest of the airway in situ. Secretions were radiolabeled biosynthetically by the administration of two radiolabeled precursors: [35S]sodium sulphate and [3H]gluc... | ['Animals', 'Atropine', 'Blood Physiological Phenomena', 'Carboxymethylcellulose Sodium', 'Cats', 'Chromatography, Gel', 'Female', 'Male', 'Mucus', 'Propranolol', 'Sulfur Radioisotopes', 'Trachea', 'Tritium'] | 7,065,525 | [['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['G09.188'], ['D09.698.365.180.663.329'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.196.181.400.250'], ['A12.200.503'], ['D02.033.100.624.698.711', 'D02.033... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolonged emergency department length of stay is not associated with worse outcomes in traumatic brain injury. | BACKGROUND: Data suggest that prolonged Emergency Department length of stay (EDLOS) has a detrimental effect on outcomes in some critically ill patients. However, the relationship between EDLOS and outcomes in traumatic brain injury (TBI) has not been examined.OBJECTIVE: Our objective was to determine the effect of EDL... | ['Adult', 'Age Factors', 'Aged', 'Brain Injuries', 'Emergency Service, Hospital', 'Female', 'Glasgow Outcome Scale', 'Hematoma, Epidural, Cranial', 'Humans', 'Intensive Care Units', 'Intubation, Intratracheal', 'Length of Stay', 'Male', 'Middle Aged', 'Patient Transfer', 'Prognosis', 'Reflex, Pupillary', 'Retrospective... | 23,769,388 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.308.940.968.875.260', 'E05.944.510', 'N04.452.859.564.800.260', 'N05.715.360.300.715.500.800.335'... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Consultation-liaison psychiatry and clinical ethics. Representative cases. | The skills of the consultation-liaison psychiatrist are enormously valuable in the emerging field of clinical ethics consultation. Expertise in evaluating decision-making capacity is crucial, as is the larger issue of addressing the role that emotional factors play in making life or death decisions. Three cases are rev... | ['Adult', 'Ethicists', 'Ethics Consultation', 'Ethics, Clinical', 'Ethics, Medical', 'Female', 'Humans', 'Male', 'Psychiatry', 'Referral and Consultation', 'Suicide, Attempted', 'Therapeutic Human Experimentation'] | 9,217,402 | [['M01.060.116'], ['K01.752.566.479.119', 'M01.526.276', 'N05.350.262'], ['K01.752.566.479.117.200', 'N04.452.758.849.174', 'N05.350.250.200'], ['K01.752.566.479.045.500', 'K01.752.566.479.171.132', 'N05.350.200.500', 'N05.350.340.162'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Hierarchical Bayesian modeling in dichotomous processes in the presence of nonresponse. | Sampling units that do not answer a survey may dramatically affect the estimation results of interest. The response may even be conditional on the outcome of interest in the survey. If estimates are found using only those who responded, the estimate may be biased, known as nonresponse bias. We are interested in finding... | ['Animals', 'Animals, Wild', 'Bayes Theorem', 'Bias', 'Biometry', 'Data Collection', 'Linear Models', 'Markov Chains', 'Missouri', 'Monte Carlo Method', 'Sampling Studies', 'Turkeys'] | 15,032,773 | [['B01.050'], ['B01.050.050.300'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['N05.715.350.150', 'N06.850.490.500'], ['E05.318.740.225', 'N06.850.505.200'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
IVS8+1 DelG, a Novel Splice Site Mutation Causing DFNA5 Deafness in a Chinese Family. | BACKGROUND: Nonsyndromic hearing loss (NSHL) is highly heterogeneous, in which more than 90 causative genes have currently been identified. DFNA5 is one of the deafness genes that known to cause autosomal dominant NSHL. Until date, only five DFNA5 mutations have been described in eight families worldwide. In this study... | ['Adult', 'Deafness', 'Exons', 'Female', 'Hearing Loss', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Young Adult'] | 26,365,971 | [['M01.060.116'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['G05.360.340.024.340.137.232'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Ecology and epidemiology of tick-borne borreliosis in the Ul'ianovsk region]. | The parameters that characterize the affection and spread of ticks in the Ulyanovsk Region are presented. A risk for Ixodes tick-borne borreliosis among the urban population is shown. | ['Animals', 'Arachnid Vectors', 'Borrelia', 'Ecology', 'Humans', 'Ixodes', 'Lyme Disease', 'Prevalence', 'Risk Factors', 'Russia', 'Urban Population'] | 12,886,596 | [['B01.050'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['B03.440.425.410.711.193', 'B03.851.595.193'], ['H01.158.273.248', 'H01.277.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.131.166.132.832.400.425'], ['C01.150.252.400.536', 'C01.150.252.400.794.352.250', 'C01.920.930.513'... | ['Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Fatality risk assessment and modeling of drivers responsibility for causing traffic accidents in Dubai. | INTRODUCTION: This paper examines crash and safety statistics from the Emirate of Dubai in an attempt to identify factors responsible for making this population at greater risk of crashes compared to other countries.PROBLEM: In developing countries such as the United Arab Emirates (U.A.E.), motor-vehicle-related mortal... | ['Accidents, Traffic', 'Age Factors', 'Automobile Driving', 'Causality', 'Humans', 'Risk Assessment', 'Sex Factors', 'United Arab Emirates', 'Wounds and Injuries'] | 12,429,105 | [['N06.850.135.392'], ['N05.715.350.075', 'N06.850.490.250'], ['I03.125'], ['N05.715.350.200', 'N06.850.490.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['N05.715.350.675', 'N06.85... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Muscle cross-bridge kinetics in rigor and in the presence of ATP analogues. | Recently we reported preliminary mechanical experiments on freshly skinned rabbit psoas fibers that suggested that while almost all of the cross-bridges are attached to actin in the presence of 4 mM adenyl-5'-yl-imidodiphosphate (AMP-PNP) (ionic strength, 0.13 M), there is an equilibrium between the attached and detach... | ['Actins', 'Adenosine Triphosphate', 'Adenylyl Imidodiphosphate', 'Animals', 'Cross-Linking Reagents', 'In Vitro Techniques', 'Kinetics', 'Muscle Contraction', 'Muscles', 'Rabbits', 'Sarcomeres', 'Solutions'] | 4,092,069 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D03.633.100.759.646.138.236.050', 'D13.695.667.138.236.050', 'D13.695.827.068.236.050'], ['B01.050'], ['D27.720.470.410.210'], ['E05.481'], ['G01.374.661', 'G02.111.49... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment, no treatment and early death in Danish stage I lung cancer patients. | BACKGROUND: Stage I lung cancer is curable with surgery as the treatment of choice. Other effective and curative treatments exist. Nevertheless, some patients only receive palliative treatment and some receive no treatment at all.MATERIALS AND METHODS: Using the Danish Lung Cancer Registry (DLCR), we assessed treatment... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Cohort Studies', 'Denmark', 'Female', 'Humans', 'Karnofsky Performance Status', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Population Groups', 'Registries', 'Survival Analysis'] | 31,027,685 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Regional delivery of anticancer drugs: current applications. | For cancers that remain confined to a specific region through most of their course, one treatment option is to deliver anticancer drugs directly to that region. Clinical experience shows that regional delivery can palliate symptoms, improve quality of life, and prolong survival. However, whether it increases the cure r... | ['Antineoplastic Agents', 'Chemotherapy, Cancer, Regional Perfusion', 'Humans', 'Infusions, Intra-Arterial'] | 10,946,454 | [['D27.505.954.248'], ['E02.319.267.200', 'E04.292.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510.520']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myosin and actomyosin from human skeletal muscle. | Human skeletal natural actomyosin contained actin, tropomyosin, troponin and myosin components as judged by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. Purified human myosin contained at least three light chains having molecular weights (+/-2000) of 25 000, 18 000 and 15 000. Inhibitory and calcium bi... | ['Actins', 'Adenosine Triphosphatases', 'Adolescent', 'Adult', 'Amino Acids', 'Calcium', 'Enzyme Activation', 'Humans', 'Kinetics', 'Molecular Weight', 'Muscles', 'Myosin Subfragments', 'Myosins', 'Peptide Fragments', 'Potassium', 'Tropomyosin', 'Troponin'] | 136,273 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D08.811.277.040.025'], ['M01.060.057'], ['M01.060.116'], ['D12.125'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G02.494'],... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Familial Creutzfeldt-Jakob disease in Japan. Three cases in a family with white matter involvement. | Three cases of Creutzfeldt-Jakob disease occurring in one family have been clinicopathologically examined. Although the age at onset, duration, and age at death differed for each case, pathological findings, including diffuse neuronal loss, astrocytosis, spongiform changes and patchy and/or diffuse white matter involve... | ['Aged', 'Brain', 'Creutzfeldt-Jakob Syndrome', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged'] | 3,884,745 | [['M01.060.116.100'], ['A08.186.211'], ['C01.207.800.230', 'C10.228.140.380.165', 'C10.228.228.800.230', 'F03.615.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Human factors systems approach to healthcare quality and patient safety. | Human factors systems approaches are critical for improving healthcare quality and patient safety. The SEIPS (Systems Engineering Initiative for Patient Safety) model of work system and patient safety is a human factors systems approach that has been successfully applied in healthcare research and practice. Several res... | ['Ergonomics', 'Humans', 'Models, Theoretical', 'Outcome and Process Assessment, Health Care', 'Patient Safety', 'Patient-Centered Care', 'Quality of Health Care', 'Systems Integration'] | 23,845,724 | [['F02.784.412', 'J01.293.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['N04.761.559', 'N05.715.360.575'], ['N06.850.135.060.075.399'], ['N04.590.233.727.407'], ['N04.761', 'N05.715'], ['H01.770.787', 'L01.906.787']] | ['Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Differential transcriptional responses between the interferon-gamma-induction and iron-limitation models of persistence for Chlamydia pneumoniae. | BACKGROUND AND PURPOSE: Chlamydia spp. are important pathogens of humans and animals that cause a wide range of acute and chronic infections. A persistence model has been developed in which Chlamydia spp. do not complete their developmental cycle, have significantly reduced infectivity for new host cells, and exhibit a... | ['Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Cell Line, Tumor', 'Chlamydophila pneumoniae', 'Gene Expression Regulation, Bacterial', 'Heat-Shock Proteins', 'Humans', 'Interferon-gamma', 'Iron', 'Models, Biological', 'Polymerase Chain Reaction', 'Reproducibility of Results'] | 19,424,556 | [['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['A11.251.210.190', 'A11.251.860.180'], ['B03.440.190.190.230.249'], ['G05.308.300'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Decatenation of kinetoplast DNA by an ATP-dependent DNA topoisomerase from the kinetoplast hemoflagellate Leishmania donovani. | An enzyme from Leishmania donovani that decatenates kinetoplast DNA networks into covalently closed monomeric circles has been isolated and characterized. The enzyme also relaxes supercoiled plasmid pBR322. The decatenation and relaxation reactions both require ATP and Mg2+. In both reactions the formation of topologic... | ['Adenosine Triphosphate', 'Animals', 'Chromatography, DEAE-Cellulose', 'Chromatography, Gel', 'DNA', 'DNA Topoisomerases, Type I', 'DNA, Superhelical', 'Kinetics', 'Leishmania donovani', 'Magnesium', 'Plasmids'] | 2,828,947 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E05.196.181.400.383.349'], ['E05.196.181.400.250'], ['D13.444.308'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.156.250'], ['G01.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Poor outcome of on-site CPR in a multi-level geriatric facility: three and a half years experience at the Baycrest Centre for Geriatric Care. | Our objective was to determine the outcome of onsite CPR in elderly patients receiving institutional care who had access to 24-hour on-site full ACLS capability. We used a retrospective chart and CPR protocol review of all patients who received CPR during the study period; these were patients or residents in a multi-le... | ['Aged', 'Cardiopulmonary Resuscitation', 'Female', 'Geriatrics', 'Heart Diseases', 'Homes for the Aged', 'Humans', 'Long-Term Care', 'Male', 'Nursing Homes', 'Ontario', 'Prognosis'] | 8,426,040 | [['M01.060.116.100'], ['E02.365.647.110'], ['H02.403.355'], ['C14.280'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.476', 'N02.421.585.476'], ['N02.278.825.610'], ['Z01.107.567.176.639'], ['E01.789']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
Risk of Stroke After the International Classification of Diseases-Ninth Revision Discharge Code Diagnosis of Hypertensive Encephalopathy. | BACKGROUND AND PURPOSE: Although chronic hypertension is a well-established risk factor for stroke, little is known about stroke risk after hypertensive encephalopathy (HE), when neurologic sequelae of hypertension become evident. Therefore, we evaluated the risk of stroke after a diagnosis of HE.METHODS: We identified... | ['Brain Ischemia', 'California', 'Case-Control Studies', 'Cerebral Hemorrhage', 'Cohort Studies', 'Female', 'Florida', 'Humans', 'Hypertension', 'Hypertensive Encephalopathy', 'International Classification of Diseases', 'Ischemic Attack, Transient', 'Kaplan-Meier Estimate', 'Male', 'New York', 'Patient Discharge', 'Pro... | 26,742,804 | [['C10.228.140.300.150', 'C14.907.253.092'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.4... | ['Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Human papillomavirus persistence and nutrients involved in the methylation pathway among a cohort of young women. | Persistent oncogenic human papillomavirus (HPV) infection is associated with cervical dysplasia. Cofactors, such as nutrient status, may be required for the progression of HPV infection to neoplasia. HPV DNA methylation patterns in vitro have been shown to be associated with viral transcriptional activity. Folate, vita... | ['Adolescent', 'Adult', 'Cell Transformation, Neoplastic', 'Cohort Studies', 'DNA Methylation', 'DNA, Viral', 'Female', 'Humans', 'Nutritional Status', 'Odds Ratio', 'Papillomaviridae', 'Papillomavirus Infections', 'Regression Analysis', 'Tumor Virus Infections', 'Uterine Cervical Neoplasms', 'Vitamin B 12'] | 11,927,495 | [['M01.060.057'], ['M01.060.116'], ['C04.697.098.500', 'C23.550.727.098.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.444.308.568'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.650', 'N... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rectal impalement injury through the pelvis, abdomen and thorax. | Impalement rectal injuries with intraperitoneal organ injuries are rare. It is even rarer for such injuries to result in pelvic, abdominal and thoracic internal injuries. We present the case of a 39-year-old man who was admitted after an assault where a broken broomstick was inserted forcibly into his rectum. Surgery ... | ['Abdominal Injuries', 'Adult', 'Foreign Bodies', 'Humans', 'Male', 'Pelvis', 'Rectum', 'Thoracic Injuries', 'Tomography, X-Ray Computed', 'Violence', 'Wounds, Penetrating'] | 22,943,322 | [['C26.017'], ['M01.060.116'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.600'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['C26.891'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['I01.198.24... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ | Apoptotic cell death of Dendritic cells (DCs) is critical for immune homeostasis. Although intrinsic mechanisms controlling DC death have not been fully characterized up to now, experimentally enforced inhibition of DC-death causes various autoimmune diseases in model systems. We have generated mice deficient for Prote... | ['Animals', 'Antigen Presentation', 'Apoptosis', 'Bcl-2-Like Protein 11', 'CD8-Positive T-Lymphocytes', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Cross-Priming', 'Dendritic Cells', 'Homeostasis', 'Lymphocyte Activation', 'Mice', 'Mice, Knockout', 'Phosphoprotein Phosphatases'] | 30,809,231 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['G04.146.954.035'], ['D12.644.360.075.323', 'D12.776.476.075.323', 'D12.776.543.116', 'D12.776.624.664.700.025'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health service attendance patterns in an urban Aboriginal health service. | OBJECTIVES: To describe the health service attendance patterns of urban Aboriginal and Torres Strait Islander (Aboriginal) Australians and make comparisons with those of the general Australian population.DESIGN AND SETTING: General practitioner-completed survey of all attendances over two separate 2-week periods in 200... | ['Australia', 'Community Health Services', 'Female', 'Health Services Needs and Demand', 'Humans', 'Male', 'Oceanic Ancestry Group', 'Urban Population'] | 20,678,041 | [['Z01.639.100', 'Z01.678.100.373'], ['N02.421.143'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.600'], ['N01.600.900']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Application of missing pulse steady state free precession to the study of renal microcirculation. | Missing pulse steady state free precession (MP-SSFP), an extension of steady state free precession (SSFP), was evaluated for its ability to measure slow fluid flows. In experiments using flow phantoms, the MP-SSFP signal was sensitive to fluid velocities in the millimeters per second range. Isolated perfused rabbit kid... | ['Animals', 'Electromagnetic Fields', 'Female', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Kidney Cortex', 'Kidney Medulla', 'Magnetic Resonance Imaging', 'Microcirculation', 'Models, Cardiovascular', 'Perfusion', 'Rabbits', 'Regional Blood Flow', 'Renal Circulation', 'Rheology', 'Time Factors'] | 1,943,663 | [['B01.050'], ['G01.358.500.260', 'G01.358.750.500'], ['E01.370.350.600.350', 'L01.224.308.380'], ['L01.224.308'], ['A05.810.453.324'], ['A05.810.453.466'], ['E01.370.350.825.500'], ['G09.330.100.645'], ['E05.599.395.161'], ['E05.680'], ['B01.050.150.900.649.313.968.700'], ['G09.330.100.780'], ['G08.852.725', 'G09.330.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Perspectives of Chinese American smoker and nonsmoker household pairs about the creating smokefree living together program. | BACKGROUND: Chinese men smoke at high rates, and this puts household members at risk for tobacco-related diseases. Culturally responsive interventions that provide education and support are needed to promote smokefree living and reduce smoke exposure, particularly for US immigrants who experience changes in smokefree s... | ['Adult', 'Aged', 'Aged, 80 and over', 'Asian Americans', 'Early Intervention, Educational', 'Female', 'Follow-Up Studies', 'Health Behavior', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Non-Smokers', 'Prognosis', 'San Francisco', 'Smokers', 'Smoking Prevention', 'Tobacco Use Disorder'] | 29,578,597 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200.100', 'M01.686.754.225'], ['N02.421.143.130.320', 'N02.421.726.320'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.145.488'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Elasto-thixotropic properties of bronchial mucus and polymer analogs. I. Experimental results. | The non-newtonian viscous and elasto-thixotropic properties of native and lyophilized pathological bronchial mucus and of polymer solutions (3% and 6% PIB in decalin) used as mucus analogs were analyzed using a cone-plate Carri-Med rheometer and a Couette viscoelastometer that we have specifically developed for measuri... | ['Bronchi', 'Bronchitis', 'Cilia', 'Elasticity', 'Humans', 'Microscopy, Electron, Scanning', 'Mucus', 'Polyenes', 'Polymers', 'Viscosity'] | 3,830,276 | [['A04.411.125'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['A11.284.180.165'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A12.200.503'], ['D02.455.326.271.665'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G02.930']] | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Characterisation of the effector cells in antibody-dependent and spontaneous cell-mediated cytotoxicity in swine against target cells infected with transmissible gastroenteritis virus. | When porcine peripheral blood leucocytes were fractionated, lymphocytes were the most active effectors in both antibody-dependent cell-mediated cytotoxicity (ADCC) and spontaneous cell-mediated cytotoxicity (SCMC), although both polymorphs and macrophages showed some activity in ADCC. Adsorption of lymphocytes to antib... | ['Animals', 'Antibody-Dependent Cell Cytotoxicity', 'Gastroenteritis, Transmissible, of Swine', 'Macrophages', 'Rosette Formation', 'Swine', 'T-Lymphocytes, Cytotoxic'] | 3,489,968 | [['B01.050'], ['G12.287.070'], ['C01.925.782.600.550.200.400', 'C22.905.469'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['E01.370.225.812.706', 'E05.200.812.706', 'E05.478.594.730'], ['B01.050.150.900.649.313.500.880'], ['A11.118.637.555.283.875', 'A11.118.637.555.567.550.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of the plasma profiles of two slow-release theophylline preparations (Nuelin depot and Theo-dur) in healthy volunteers. | Fourteen healthy volunteers were given Theo-Dur or Nuelin Depot 250 mg b.i.d. in a cross-over study. Almost identical plasma concentrations of theophylline were found after both preparations, as assessed from plasma level measurements performed before intake and on several occasions up to 12 hours after intake of the n... | ['Adult', 'Delayed-Action Preparations', 'Female', 'Humans', 'Kinetics', 'Male', 'Theophylline'] | 7,235,323 | [['M01.060.116'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D03.132.960.751', 'D03.633.100.759.758.824.751']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Improvement of epidemiological surveillance of meningococcus infection and it's selective prophylaxis in troops]. | The article is devoted to a critical analyze of existent system of epidemiological surveillance for morbidity of meningococcus infection among population and military service men, and to condition and perspectives of immuno- and chemoprophylaxis of correspondent generalized forms of diseases in the world, Russia and it... | ['Community-Acquired Infections', 'Humans', 'Meningococcal Infections', 'Military Medicine', 'Military Personnel', 'Population Surveillance', 'Russia'] | 19,916,316 | [['C01.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.625.549'], ['H02.403.500'], ['M01.526.625'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Non-smoky glycosyltransferase1 prevents the release of smoky aroma from tomato fruit. | Phenylpropanoid volatiles are responsible for the key tomato fruit (Solanum lycopersicum) aroma attribute termed "smoky." Release of these volatiles from their glycosylated precursors, rather than their biosynthesis, is the major determinant of smoky aroma in cultivated tomato. using a combinatorial omics approach, we ... | ['Chromatography, Liquid', 'Chromosome Segregation', 'Chromosomes, Plant', 'Eugenol', 'Fruit', 'Gene Expression Regulation, Plant', 'Genetic Markers', 'Genome, Plant', 'Glycosides', 'Glycosylation', 'Glycosyltransferases', 'Guaiacol', 'Humans', 'Lycopersicon esculentum', 'Mass Spectrometry', 'Metabolome', 'Molecular Se... | 23,956,261 | [['E05.196.181.400'], ['G04.144.220.220.625', 'G05.113.220.625'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['D02.241.223.200.054.500'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G05.308.375'], ['D23.101.387', 'G05.695.450'], ['G05.360.340.365'], ['D09.408'], ['G02.111.158.812', 'G02.607.299', 'G03.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
In vitro studies of steroid hormones in neurofibromatosis 1 tumors and Schwann cells. | The most common NF1 feature is the benign neurofibroma, which consists predominantly of Schwann cells. Dermal neurofibromas usually arise during puberty and increase in number throughout adulthood. Plexiform neurofibromas, associated with larger nerves, are often congenital and can be life threatening. Malignant periph... | ['Apoptosis', 'Cell Proliferation', 'ErbB Receptors', 'Female', 'Gene Expression', 'Humans', 'Immunoenzyme Techniques', 'In Situ Nick-End Labeling', 'In Vitro Techniques', 'Male', 'Neurofibromatosis 1', 'RNA, Messenger', 'Receptor, ErbB-2', 'Receptors, Androgen', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Recep... | 17,393,410 | [['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E05.393.475'], ['E05.481'], ['C04.55... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The pro-fibrotic and pro-oxidant action of isoniazid]. | As a result of experimental research on rats with destructive pulmonary tuberculosis, oxidative action of isoniazid in a dose of 50 mg per kg body weight, corresponding to the mean therapeutic dose of 10 mg/kg in man, was clearly defined. Fibrotic action of the drug was also shown. It manifested itself by a sharp rise ... | ['Animals', 'Isoniazid', 'Lipid Peroxidation', 'Pulmonary Fibrosis', 'Rats', 'Tuberculosis, Pulmonary'] | 2,255,708 | [['B01.050'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['G02.111.515', 'G03.295.531.587'], ['C08.381.765'], ['B01.050.150.900.649.313.992.635.505.700'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Primary structure of the NH2-terminal extra piece of the precursor to human placental lactogen. | The cell-free translation product of human placental lactogen mRNA is a precursor molecule larger than the mature hormone that circulates in plasma. To determine the structure of pre-placental lactogen, the poly(A)-rich RNA fraction of term placenta was isolated and translated in a wheat germ cell-free system. The mRNA... | ['Amino Acid Sequence', 'Biological Evolution', 'Female', 'Growth Hormone', 'Humans', 'Molecular Weight', 'Peptide Fragments', 'Placental Lactogen', 'Pregnancy', 'Prolactin', 'Protein Biosynthesis', 'Protein Precursors'] | 291,043 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques. | C-reactive protein (CRP) is a predictor of cardiovascular risk. It circulates as a pentamer (pentameric CRP) in plasma. The in vivo existence of monomeric (m)CRP has been postulated, but its function and source are not clear. We show that mCRP is deposited in human aortic and carotid atherosclerotic plaques but not in ... | ['Aortic Diseases', 'Apoptosis', 'Atherosclerosis', 'Autopsy', 'Blood Platelets', 'C-Reactive Protein', 'Carotid Artery Diseases', 'Cell Adhesion', 'Chemotaxis, Leukocyte', 'Endothelial Cells', 'Humans', 'Inflammation', 'Inflammation Mediators', 'Jurkat Cells', 'Lysophosphatidylcholines', 'Macrophage-1 Antigen', 'Membr... | 19,520,972 | [['C14.907.109'], ['G04.146.954.035'], ['C14.907.137.126.307'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['A11.118.188', 'A15.145.229.188'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C10.228.140.300.200', 'C14.907.253.123'], ['G04.022'], ['G04.198.424.233'], ['A11.436.275'], ['B01.0... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses. | The transporter associated with antigen processing (TAP) transports short peptides from the cytosol to the endoplasmic reticulum, where peptides assemble with class I molecules of the major histocompatibility complex. TAP is comprised of two subunits, termed TAP1 and TAP2. We produced recombinant vaccinia viruses that ... | ['ATP Binding Cassette Transporter, Subfamily B, Member 2', 'ATP Binding Cassette Transporter, Subfamily B, Member 3', 'ATP-Binding Cassette Transporters', 'Cell Line', 'Detergents', 'Fluorescent Antibody Technique', 'Glycosylation', 'Humans', 'Major Histocompatibility Complex', 'Microscopy, Confocal', 'Nucleotides', '... | 7,673,167 | [['D12.776.157.530.100.075.250', 'D12.776.157.530.450.074.500.500.250.250', 'D12.776.395.550.020.400.305', 'D12.776.543.550.192.400.305', 'D12.776.543.585.100.200.250', 'D12.776.543.585.450.074.500.500.250.250'], ['D12.776.157.530.100.075.500', 'D12.776.157.530.450.074.500.500.250.375', 'D12.776.395.550.020.400.458', '... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A qualitative study examining the experience of primary care dentists in the detection and management of potentially malignant lesions. 2. Mechanics of the referral and patient communication. | BACKGROUND AND AIMS: The diagnosis of early and pre-malignant lesions of oral squamous cell carcinoma is of paramount importance given the mortality rate of late stage disease. Although studies have been undertaken examining how dentists manage and refer potentially malignant lesions, the majority of the research has u... | ['Adult', 'Attitude of Health Personnel', 'Carcinoma, Squamous Cell', 'Early Detection of Cancer', 'Female', 'General Practice, Dental', 'Health Promotion', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Patient Acceptance of Health Care', "Practice Patterns, Dentists'", 'Qualitative Resear... | 20,098,361 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.390.500'], ['H02.163.342'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Mechanical properties of trabecular bone within and adjacent to osseous metastases. | Despite radiographic and histologic evidence of trabecular bone density changes within and adjacent to osseous metastases, there currently exist no data to demonstrate whether these changes are important in predicting the risk of fracture. To determine if these density changes result in significant reductions in mechan... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Bone Density', 'Breast Neoplasms', 'Female', 'Humans', 'Lumbar Vertebrae', 'Radiography', 'Regression Analysis', 'Spinal Neoplasms', 'Stress, Mechanical', 'Thoracic Vertebrae'] | 1,456,084 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G11.427.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['E01.370.350.700'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.83... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preclinical diagnosis of chronic wasting disease in captive mule deer (Odocoileus hemionus) and white-tailed deer (Odocoileus virginianus) using tonsillar biopsy. | The usefulness of tonsillar biopsy on live deer for preclinical diagnosis of the transmissible spongiform encephalopathy chronic wasting disease (CWD) was evaluated. Disease was tracked in a CWD-endemic herd using serial tonsillar biopsies collected at 6 to 9 month intervals from 34 captive mule deer (Odocoileus hemion... | ['Animals', 'Chronic Disease', 'Deer', 'Female', 'Immunoenzyme Techniques', 'Male', 'Palatine Tonsil', 'Prion Diseases', 'Prions', 'Staining and Labeling', 'Wasting Syndrome'] | 12,237,447 | [['B01.050'], ['C23.550.291.500'], ['B01.050.150.900.649.313.500.380.373'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A04.623.603.925', 'A10.549.580', 'A14.724.603.925', 'A15.382.520.604.580'], ['C01.207.800', 'C10.228.228.800', 'C10.574.843'], ['D12.776.785'], ['E01.370.225.500.620.670', 'E01.370.22... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conservative Management of Vaginal Hypoplasia | In patients with Mayer-Rokitansky-K?ster-Hauser syndrome and complete androgen insensitivity syndrome (CAIS), management of vaginal hypoplasia includes non-surgical or surgical vaginal elongation techniques. For these patients, primary vaginal dilation is considered a first-line option to avoid the risks of having surg... | ['Adolescent', 'Androgen-Insensitivity Syndrome', 'Conservative Treatment', 'Dilatation', 'Female', 'Humans', 'Male', 'Vagina'] | 32,041,393 | [['M01.060.057'], ['C12.706.316.096.500', 'C13.351.875.253.096.500', 'C16.131.939.316.096.500', 'C16.320.322.061', 'C19.391.119.096.500'], ['E02.197'], ['E05.284'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.319.779']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular structure of redox metal centers of the cytochrome bo complex from Escherichia coli. Spectroscopic characterizations of the subunit I histidine mutant oxidases. | A site-directed mutagenesis study on the conserved subunit I histidines of the cytochrome bo complex in Escherichia coli identified ligands of the low spin heme B and CuB centers; however, the assignment of the proximal ligand of the high spin heme O was ambiguous (Minagawa, J., Mogi, T., Gennis, R. B., and Anraku, Y. ... | ['Copper', 'Cytochrome b Group', 'Cytochromes', 'Electron Spin Resonance Spectroscopy', 'Escherichia coli', 'Escherichia coli Proteins', 'Histidine', 'Iron', 'Mutation', 'Oxidation-Reduction', 'Oxidoreductases', 'Spectrum Analysis, Raman'] | 7,983,018 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D08.244.187', 'D12.776.422.220.187'], ['D08.244', 'D12.776.422.220'], ['E05.196.867.519.274'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D12.125.072.329', 'D12.125.142.308'], ['D01.268.556.412', 'D01.268.956.287', 'D01.55... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-grade dysplastic adenoma-like mass lesions are not an indication for colectomy in patients with ulcerative colitis. | OBJECTIVE: The management of high-grade dysplasia (HGD) in polypoid lesions in patients with ulcerative colitis (UC) is not well characterized. The purpose of this study was to characterize the clinical course of patients with HGD in adenoma-like dysplasia-associated lesion or masses (DALMs) in the absence of any synch... | ['Adenoma', 'Adult', 'Aged', 'Colectomy', 'Colitis, Ulcerative', 'Colonic Neoplasms', 'Colonoscopy', 'Female', 'Humans', 'Male', 'Middle Aged'] | 18,584,520 | [['C04.557.470.035'], ['M01.060.116'], ['M01.060.116.100'], ['E04.210.219'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vasitis: a clinical confusion diagnosis with inguinal hernia. | Vasitis or inflammation of the vas deferens is a rarely described condition categorized as ei-ther generally asymptomatic vasitis nodosa or the acutely painful infectious vasitis. Vasitis nodosa, the commonly described inflammation of the vas deferens, is benign and usually associated with a history of vasectomy. Clini... | ['Adult', 'Diagnosis, Differential', 'Hernia, Inguinal', 'Humans', 'Male', 'Orchitis', 'Rare Diseases', 'Spermatic Cord', 'Tomography, X-Ray Computed', 'Vas Deferens'] | 30,901,176 | [['M01.060.116'], ['E01.171'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.829.493', 'C19.391.829.493'], ['C23.550.291.906'], ['A05.360.444.777'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A radiobiological Markov simulation tool for aiding decision making in proton therapy referral. | PURPOSE: Proton therapy can be a highly effective strategy for the treatment of tumours. However, compared with X-ray therapy it is more expensive and has limited availability. In addition, it is not always clear whether it will benefit an individual patient more than a course of traditional X-ray therapy. Basing a tre... | ['Child', 'Chordoma', 'Decision Making', 'Humans', 'Male', 'Markov Chains', 'Neoplasms, Second Primary', 'Proton Therapy', 'Quality-Adjusted Life Years', 'Radiobiology', 'Referral and Consultation', 'Skull Neoplasms'] | 29,254,594 | [['M01.060.406'], ['C04.557.465.220'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.850.520.830.996.500'], ['C04.692'], ['E02.815.250.500'], ['E05.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Concurrent chemoradiotherapy with S-1 for T2N0 glottic squamous cell carcinoma. | In this study, we evaluated the feasibility, efficacy and toxicity of concurrent chemoradiotherapy with S-1 (tegafur-gimeracil-oteracil potassium) for T2N0 glottic carcinoma. A total of 23 patients with T2N0 glottic carcinoma received chemoradiotherapy with S-1. Radiotherapy consisted of five daily fractions of 2 Gy pe... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Drug Combinations', 'Glottis', 'Humans', 'Kaplan-Meier Estimate', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', 'Oxonic Acid', 'Pyridines', 'Radiation-Sensitizing Agents', 'Tegafur'] | 20,601,829 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['D26.310'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['C04.588.443.665.48... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Obesity in free-ranging rhesus macaques. | Spontaneous obesity in free-ranging rhesus macaques (Macaca mulatta) was assessed in terms of body size, body fat distribution, endocrinological/metabolic indices, and social and familial factors. Eleven animals (six females, five males), or 7% of the adult population surveyed, were defined as obese on the basis of mor... | ['Animals', 'Blood Chemical Analysis', 'Body Constitution', 'Female', 'Glucose Tolerance Test', 'Macaca mulatta', 'Male', 'Monkey Diseases', 'Obesity', 'Puerto Rico', 'Social Behavior', 'Social Environment'] | 8,383,634 | [['B01.050'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E01.370.600.115', 'G07.100'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['C22.735.500'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
How nursing leadership and management interventions could facilitate the effective use of ICT by student nurses. | AIM: This article makes the case for how evidence-based nursing leadership and management activities could promote, implement and sustain quality patient care by student nurses using Information and Communications Technology. It is on aspects of the findings of a professional doctorate inquiry into Information and Comm... | ['Attitude of Health Personnel', 'Attitude to Computers', 'Computer Literacy', 'Computer User Training', 'Education, Nursing, Baccalaureate', 'Health Knowledge, Attitudes, Practice', 'Health Services Needs and Demand', 'Humans', 'Interprofessional Relations', 'Leadership', 'Mentors', 'Nurse Administrators', "Nurse's Ro... | 17,352,704 | [['F01.100.050', 'N05.300.100'], ['F01.100.100'], ['L01.143.256'], ['I02.903.080'], ['I02.358.462.316'], ['F01.100.150.500', 'N05.300.150.410'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['F01.752.609'], ['M01.395'], ['M01.526.070.670', 'M01.526.485.650.58... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Sutureless closure of the upper eyelids in blepharoplasty: use of octyl-2-cyanoacrylate. | BACKGROUND: Skin adhesives provide an alternative to sutures for skin closure. The use of octyl-2-cyanoacrylate in blepharoplasty has been reported by some authors, but difficulties in applying the product and the real benefits of its use are still controversial.OBJECTIVE: The purpose of this study is to show a simple ... | ['Blepharoplasty', 'Cyanoacrylates', 'Eyelids', 'Female', 'Humans', 'Middle Aged', 'Prospective Studies', 'Research Design', 'Surgical Wound Dehiscence', 'Suture Techniques', 'Sutures', 'Tissue Adhesives', 'Treatment Outcome'] | 19,371,837 | [['E04.540.104', 'E04.680.275.090'], ['D02.241.081.069.366', 'D02.626.290', 'D05.750.259', 'D25.720.259', 'D25.919.367', 'J01.637.051.720.259', 'J01.637.051.919.367'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Insulin and vanadate restore decreased plasma endothelin concentrations and exaggerated vascular responses to normal in the streptozotocin diabetic rat. | Although insulin has been shown to raise plasma concentrations of endothelin (ET) and up regulate vascular smooth muscle ETA receptor expression, the interaction of vanadate, an insulinomimetic agent, with the vascular ET system has not been investigated. We compared the effects of oral vanadate treatment (0.5 mg/ml; p... | ['Animals', 'Aorta', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Endothelin-1', 'Insulin', 'Male', 'Methoxamine', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Rats', 'Rats, Sprague-Dawley', 'Vanadates', 'Vasoconstrictor Agents'] | 9,794,113 | [['B01.050'], ['A07.015.114.056'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D02.033.100.624.536', 'D02.033.755.624.536', 'D02.092.063.624.53... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Behavior of the complement components C3 and C4, C-reactive protein and blood sedimentation rate for activity control in arthritis patients during thermo-hydrotherapy]. | 21 male patients suffering since years from classical rheumatoid arthritis were treated with daily thermal baths of 37 degrees Celsius temperature during a 3 week period. To control the activity of the rheumatoid inflammation we used the complement components C3 and C4, the C-reactive protein and the blood sedimentatio... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Austria', 'Blood Sedimentation', 'C-Reactive Protein', 'Complement C3', 'Complement C4', 'Health Resorts', 'Hot Temperature', 'Humans', 'Hydrotherapy', 'Male', 'Middle Aged'] | 629,093 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['Z01.542.088'], ['E01.370.225.625.125', 'E05.200.625.125'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274.350'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Coexistence of Kaposi's sarcoma and angioimmunoblastic lymphadenopathy. | A 66-year-old woman who developed simultaneously angioimmunoblastic lymphadenopathy (AILD) and Kaposi's sarcoma (KS) is reported. A parallel course of the two diseases was evident. After a relatively short course of corticosteroid therapy, the clinical and laboratory signs of AILD regressed, and the patient is in remis... | ['Aged', 'Female', 'Humans', 'Immunoblastic Lymphadenopathy', 'Prednisone', 'Sarcoma, Kaposi', 'Skin Neoplasms'] | 3,965,524 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604.338.500', 'C15.604.515.509', 'C20.683.515.501'], ['D04.210.500.745.432.719.702'], ['C01.925.256.466.860', 'C04.557.450.795.850', 'C04.557.645.750'], ['C04.588.805', 'C17.800.882']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Sciatic pain and intervertebral disc prolapse after gynecologic operations]. | Among 65 patients operated by lumbar disc in 1977 we encountered 5 women after gynecological tumour operations. 4 of those patients not became symptom free. The relation of mechanical factors, obstruction and circulation changes seemed to be of importance for the evaluation of ischialgia in those cases and led to spina... | ['Castration', 'Cesarean Section', 'Female', 'Genitalia, Female', 'Humans', 'Hysterectomy', 'Intervertebral Disc Displacement', 'Postoperative Complications', 'Sciatica'] | 532,470 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Virtual slant explains perceived slant, distortion, and motion in pictorial scenes. | Virtual slants of obliquely viewed figures consisting of skewed grids, computed as a function of depicted slant and slant of the physical surface, were compared with perceived slants in both monocular and binocular viewing conditions. Computations were based on an assumption of parallelism. Perceived slant was well-cor... | ['Depth Perception', 'Humans', 'Linear Models', 'Motion Perception', 'Optical Illusions', 'Orientation', 'Pattern Recognition, Visual', 'Perceptual Distortion', 'Psychophysics', 'User-Computer Interface', 'Vision, Binocular', 'Vision, Monocular'] | 23,837,203 | [['F02.463.593.200', 'F02.463.593.778.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['F02.463.593.932.567'], ['F02.463.593.446.659'], [... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Use of a balloon catheter in management of the pelvic space following laparoscopic abdominoperineal excision. | AIM: Management of the pelvic space following laparoscopic abdominoperineal excision remains controversial. We describe a simple technique for obliteration of the pelvic space after laparoscopic abdominoperineal excision.METHOD: Pneumoperitoneum was re-established after completion of the operative procedure and a Foley... | ['Abdomen', 'Aged', 'Aged, 80 and over', 'Catheters', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Pelvis', 'Perineum', 'Postoperative Complications', 'Rectal Neoplasms'] | 22,413,753 | [['A01.923.047'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E07.132'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['A01.923.600'], ['A01.719'], ['C23.550.767'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.79... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Application of a screening test for depression in the Health Counselling Center. | This paper outlines the process of development and the clinical usefulness of a screening test for depression. First we developed a draft questionnaire consisting of 13 items, each of which had three answers--(1) often, (2) sometimes, (3) none--, with reference to certain kinds of rating scales. After each answer was q... | ['Algorithms', 'Community Health Centers', 'Counseling', 'Depression', 'Humans', 'Surveys and Questionnaires'] | 3,449,986 | [['G17.035', 'L01.224.050'], ['N02.278.035.128'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Comparative tests of parasite species richness in primates. | Some hosts harbor diverse parasite communities, whereas others are relatively parasite free. Many factors have been proposed to account for patterns of parasite species richness, but few studies have investigated competing hypotheses among multiple parasite communities in the same host clade. We used a comparative data... | ['Animals', 'Biodiversity', 'Body Constitution', 'Diet', 'Environment', 'Geography', 'Parasites', 'Phylogeny', 'Population Dynamics', 'Primates'] | 14,618,538 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['E01.370.600.115', 'G07.100'], ['G07.203.650.240'], ['G16.500.275', 'N06.230'], ['H01.277.500'], ['B01.050.500.714'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['B01.050.150.900.649.313.988']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Dynamics of Persistent Oral Cytomegalovirus Shedding During Primary Infection in Ugandan Infants. | Cytomegalovirus (CMV) infection occurs frequently in young children, who, when infected, are then a major source of transmission. Oral CMV shedding by 14 infants with primary infection was comprehensively characterized using quantitative polymerase chain reaction weekly for ?9 months. Three phases of oral shedding were... | ['Child, Preschool', 'Cohort Studies', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Models, Theoretical', 'Mouth', 'Pregnancy', 'Real-Time Polymerase Chain Reaction', 'Time Factors', 'Uganda', 'Virus Shedding'] | 27,651,417 | [['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.599'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['G08.686.784.769'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Antisense oligonucleotide attenuates renal tubulointerstitial injury in mice with unilateral ureteral obstruction]. | OBJECTIVE: To inhibit the expression of ICAM-1 mRNA with the mouse ICAM-1 phosphorothioate antisense oligodeoxynucleotide (ASON) and to investigate the role of ICAM-1 in the pathophysialogical process of renal injury in unilateral ureteral obstruction (UUO) animal model.METHODS: After unilateral ureteral ligation, the ... | ['Animals', 'Female', 'Intercellular Adhesion Molecule-1', 'Kidney', 'Male', 'Mice', 'Nephritis, Interstitial', 'Oligodeoxyribonucleotides', 'Oligodeoxyribonucleotides, Antisense', 'Ureteral Obstruction'] | 11,715,426 | [['B01.050'], ['D12.776.395.550.200.450', 'D12.776.543.550.200.450', 'D23.050.301.350.450'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['C12.777.419.570.643', 'C13.351.968.419.570.643'], ['D13.695.578.424.450'], ['D13.150.200.640', 'D13.150.480.640', 'D13.444.308.150.640', 'D13.444.600.150.200.640',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Meeting report: the fifth Genomic Standards Consortium (GSC) workshop. | This meeting report summarizes the proceedings of the fifth Genomic Standards Consortium (GSC) workshop held December 12-14, 2007, at the European Bioinformatics Institute (EBI), Cambridge, UK. This fifth workshop served as a milestone event in the evolution of the GSC (launched in September 2005); the key outcome of t... | ['Education', 'Genomics', 'Reference Standards'] | 18,564,915 | [['I02'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.978.808']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Effect of long-term administration of finasteride (MK-906), an inhibitor of 5 alpha-reductase, in patients with benign prostatic hyperplasia. | We evaluated the effect of long-term administration of finasteride (MK-906), a potent inhibitor of 5 alpha-reductase in patients with benign prostatic hyperplasia (BPH). The effect of an increase in dose was also assessed. Finasteride was administered to 61 patients with BPH at the dose of 1 mg/day for 48 weeks. Thirty... | ['5-alpha Reductase Inhibitors', 'Aged', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Enzyme Inhibitors', 'Finasteride', 'Humans', 'Male', 'Middle Aged', 'Prostatic Hyperplasia', 'Testosterone', 'Urodynamics'] | 8,693,970 | [['D27.505.519.389.870.200', 'D27.505.696.399.450.855.200'], ['M01.060.116.100'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['D27.505.519.389'], ['D04.210.500.054.079.500', 'D04.210.500.925.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.294.565.500'], ['D04.210.500... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hospital-acquired infection rate in a tertiary care teaching hospital in China: a cross-sectional survey involving 2434 inpatients. | A single-day hospital-acquired infections (HAIs) point prevalence study was conducted in a tertiary care hospital in China. The overall prevalence rate of HAIs was 3.53% (95% confidence interval 2.80-4.26%) among 2434 inpatients surveyed. Respiratory system infection was the most common type of HAI (49.43%), followed b... | ['China', 'Cross Infection', 'Cross-Sectional Studies', 'Data Collection', 'Escherichia coli', 'Escherichia coli Infections', 'Hospitals, Teaching', 'Humans', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Prevalence', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Tertiary Care Centers'] | 25,107,465 | [['Z01.252.474.164'], ['C01.248', 'C23.550.291.875.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['N02.278.020.300', 'N02.278... | ['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Mouse immunoglobulin allotypes: detection with rabbit antiserums. | An antiserum with allotypic specificity for mouse gamma(2a)-globulins was prepared in a rabbit by injection of 7S gamma(2)-globulin of C(57)BL/6 mice. The antibody reacted with an isoantigen in the 7S gamma(2)-globulins of normal serum of mouse strains belonging to the lg-1(b) allotype class (C(57)BL/6, C(57)BL/10, and... | ['Animals', 'Antigen-Antibody Reactions', 'Immune Sera', 'Immunodiffusion', 'Immunoelectrophoresis', 'Mice', 'Rabbits', 'gamma-Globulins'] | 4,163,015 | [['B01.050'], ['G12.122'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intensified large artery and microvascular response to cold adrenergic stimulation in African blacks. | BACKGROUND: Arterial stiffening is more accelerated in blacks than in whites. Whether this is attributed to an enhanced vascular reactivity to environmental stress stimulation remains unknown. We therefore decided to test the hypothesis that cold pressor test (CPT) elicits a greater increase in arterial stiffness and a... | ['Adult', 'Africa', 'African Continental Ancestry Group', 'Blood Pressure', 'Carotid Arteries', 'Cold Temperature', 'Elasticity', 'European Continental Ancestry Group', 'Femoral Artery', 'Heart Rate', 'Humans', 'Laser-Doppler Flowmetry', 'Male', 'Pulse', 'Regional Blood Flow', 'Skin', 'Vascular Resistance', 'Vasoconstr... | 19,521,343 | [['M01.060.116'], ['Z01.058'], ['M01.686.508.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.186'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.374.590'], ['M01.686.508.400'], ['A07.015.114.351'], ['E01.3... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Flow-modulated comprehensive two-dimensional gas chromatography combined with a high-resolution time-of-flight mass spectrometer: a proof-of-principle study. | The present research is focused on the evaluation of a recently developed high-resolution time-of-flight mass spectrometer (HR TOF MS), under the challenging conditions of a flow-modulation comprehensive two-dimensional gas chromatography (FM GC ? GC) experiment. The HR TOF MS instrument was operated at a spectral gene... | ['Gas Chromatography-Mass Spectrometry', 'Heterocyclic Compounds', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Sulfur Compounds'] | 25,642,594 | [['E05.196.181.349.500', 'E05.196.566.500'], ['D03'], ['E05.196.566.755'], ['D01.875', 'D02.886']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Shape memory alloy fixator system for suturing tissue in minimal access surgery. | A new technique for suturing human tissue is described in which tissue closure is achieved by means of small fixators made from shape memory alloy. The aim of the development is to provide an alternative to thread suturing in minimal access surgery, which is quicker and requires less skill to achieve the required sutur... | ['Alloys', 'Biocompatible Materials', 'Body Temperature', 'Elasticity', 'Endoscopy', 'Equipment Design', 'Humans', 'Materials Testing', 'Nickel', 'Stress, Mechanical', 'Surgical Instruments', 'Suture Techniques', 'Thermodynamics', 'Titanium'] | 10,548,336 | [['D01.552.033', 'D25.058', 'J01.637.051.058'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E01.370.600.875.374', 'G07.110'], ['G01.374.590'], ['E01.370.388.250', 'E04.502.250'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607']... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Computer-controlled optical scanning tile microscope. | A new type of computer-controlled optical scanning, high-magnification imaging system with a large field of view is described that overcomes the commonly believed incompatibility of achieving both high magnification and a large field of view. The new system incorporates galvanometer scanners, a CCD camera, and a high-b... | ['Equipment Design', 'Equipment Failure Analysis', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Microscopy', 'Microscopy, Confocal', 'Pattern Recognition, Automated'] | 16,523,776 | [['E05.320'], ['E05.325.192'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E01.370.350.515.395', 'E05.595.395'], ['L01.399.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. | BACKGROUND: Ingestion of a large dose of the milk sugar lactose--for example, the 50-g load in 1 liter of milk--causes symptoms such as abdominal pain, diarrhea, bloating, and flatulence in the majority of people with lactose malabsorption. It is uncertain whether the ingestion of more common doses of lactose, such as ... | ['Abdominal Pain', 'Adolescent', 'Adult', 'Animals', 'Breath Tests', 'Cross-Over Studies', 'Diarrhea', 'Double-Blind Method', 'Female', 'Flatulence', 'Humans', 'Hydrogen', 'Hydrolysis', 'Lactose', 'Lactose Intolerance', 'Male', 'Middle Aged', 'Milk'] | 7,776,987 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.057'], ['M01.060.116'], ['B01.050'], ['E01.370.100'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C23.888.821.214'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C23.888.821.360'], ['B01.050.150.90... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. | We recently showed that the 1.7 megabase multiple aberration region (MAR) on human chromosome 12q15 harbours recurrent breakpoints frequently found in a variety of benign solid tumours. We now report a candidate gene within MAR suspected to be of pathogenetical relevance. Using positional cloning, we have identified th... | ['Base Sequence', 'Chromosomes, Human, Pair 12', 'DNA Primers', 'Gene Rearrangement', 'HMGA2 Protein', 'High Mobility Group Proteins', 'Humans', 'In Situ Hybridization, Fluorescence', 'Mesoderm', 'Molecular Sequence Data', 'Neoplasms', 'RNA, Messenger', 'Tumor Cells, Cultured'] | 7,670,494 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.520.300.325.360', 'G05.360.162.520.300.325.360'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.344'], ['D12.776.260.312.937', 'D12.776.660.235.400.500.600', 'D12.776.664.235.400.500.600'], ['D12.776.660.235.400', 'D12.776.664... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of perioperative chemoimmunotherapy with cyclophosphamide and autologous tumor vaccine in murine MBT-2 bladder cancer. | The in vitro cytotoxic activity of splenocytes from C3H/He mice implanted subcutaneously with 10(6) syngeneic MBT-2 tumor cells on day 0 was significantly enhanced after cyclophosphamide (100 mg./kg., intraperitoneally) given 2 days before tumor resection on day 17, with or without active specific immunization with BCG... | ['Animals', 'Antigens, CD', 'Combined Modality Therapy', 'Cyclophosphamide', 'Female', 'Immunophenotyping', 'Immunotherapy, Adoptive', 'Lymph Nodes', 'Lymphocyte Subsets', 'Mice', 'Mice, Inbred C3H', 'Preoperative Care', 'Spleen', 'Tumor Cells, Cultured', 'Urinary Bladder Neoplasms', 'Vaccines', 'Whole-Body Irradiation... | 8,189,597 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['E02.095.465.425.400.330.050.400', 'E05.478.550.520.050.400'], ['A10.549.400', 'A15.382.520.604.412'], ['A11.118.637.555.567.550'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bone marrow donor routine HLA typing identified a novel B*07 allele, B*0734, confirmed by allele-specific DNA cycle sequencing. | In this article, we report the identification of a new human leukocyte antigen-B allele in a sample that was tested in our routine typing for bone marrow donors. This novel allele officially designed B*0734 was found in a female donor of Bavarian Caucasoid origin (Laboratory code 121036). The search for unrelated bone ... | ['Adult', 'Alleles', 'Amino Acid Substitution', 'Base Sequence', 'Bone Marrow Transplantation', 'European Continental Ancestry Group', 'Female', 'Genes, MHC Class I', 'HLA-B Antigens', 'HLA-B7 Antigen', 'Histocompatibility Testing', 'Humans', 'Molecular Sequence Data', 'Sequence Alignment', 'Sequence Analysis, DNA', 'S... | 15,853,907 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.686.508.400'], ['G05.360.340.024.340.610.595', 'G05.360.340.024.380.500.595', 'G12.500.500.595'], ['D12.776.395.550.489.500'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Protection of preglomerular vessels from angiotensin II vasoconstriction by renal prostaglandins. | Previous studies suggest that the renal vasoconstrictor effect of angiotensin II (ANG II) is confined primarily to efferent arterioles, with little direct action on preglomerular vessels. The present study examined the role of prostaglandins (PG) in protecting preglomerular vessels from ANG II constriction. In dogs in ... | ['Angiotensin II', 'Animals', 'Dogs', 'Kidney', 'Kidney Glomerulus', 'Prostaglandin Antagonists', 'Prostaglandins', 'Vascular Resistance', 'Vasoconstriction'] | 2,856,712 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A05.810.453'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['D06.347.710', 'D27.505.696.399.450.710'], ['D10.25... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The politics of place(ment): problematising the provision of hepatitis C treatment within opiate substitution clinics. | The hepatitis C virus (HCV) epidemic is a significant public health challenge in Australia. Current initiatives to expand access to HCV treatment focus on opiate substitution therapy (OST) settings where the prevalence of hepatitis C among clients is high. In Australia, the provision of OST for many clients is via larg... | ['Ambulatory Care Facilities', 'Antiviral Agents', 'Australia', 'Cross-Sectional Studies', 'Female', 'Health Care Surveys', 'Health Services Accessibility', 'Hepatitis C', 'Humans', 'Interferons', 'Interviews as Topic', 'Male', 'Methadone', 'Narcotics', 'Opiate Substitution Treatment', 'Politics', 'Prejudice', 'Ribavir... | 22,133,583 | [['N02.278.035'], ['D27.505.954.122.388'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['C01.221.250... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Effect of isoprenaline on plasma leptin and lipolysis in humans. | OBJECTIVE: The sympathetic nervous system may play a central role in the regulation of both lipolysis and leptin production. Therefore, we investigated the effect of intravenous infusions of the beta-adrenergic agonist isoprenaline on plasma concentrations of leptin and nonesterified fatty acids.DESIGN AND PATIENTS: Ei... | ['Adrenergic beta-Agonists', 'Adult', 'Biomarkers', 'Depression, Chemical', 'Fatty Acids, Nonesterified', 'Female', 'Humans', 'Infusions, Intravenous', 'Insulin', 'Isoproterenol', 'Leptin', 'Lipolysis', 'Male', 'Proteins'] | 9,640,406 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['M01.060.116'], ['D23.101'], ['G07.690.773.750'], ['D10.251.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D02.033.100.291.439', 'D... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Specific association of teratogen and toxicant metals in hair of newborns with congenital birth defects or developmentally premature birth in a cohort of couples with documented parental exposure to military attacks: observational study at Al Shifa Hospital, Gaza, Palestine. | This study was undertaken in Gaza, Palestine, in a cohort of babies born in 2011. Hair samples of newborns were analyzed for metal load by DRC-ICP-MS. We report specific level of contamination by teratogen/toxicants metals of newborn babies, environmentally unexposed, according to their phenotypes at birth: normal full... | ['Cohort Studies', 'Congenital Abnormalities', 'Environmental Exposure', 'Environmental Pollutants', 'Female', 'Hair', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Metals', 'Middle East', 'Parents', 'Pregnancy', 'Premature Birth', 'Prenatal Exposure Delayed Effects', 'Teratogens', 'Time Factors'] | 24,830,451 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C16.131'], ['N06.850.460.350'], ['D27.888.284'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['D01.552'], ['Z01.252.245.500'], ['F01.829.263.500.320', 'I01.880.853.150.500.34... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and ... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Salvage method for unplanned excision of soft tissue sarcoma: long-term results of second-look surgery following radio-hyperthermo-chemotherapy. | We have established a "second-look operation" protocol that consists of whole biopsy of surgical scar tissue following radio-hyperthermo-chemotherapy (RHC) after unplanned excision of soft tissue sarcoma. Out of 30 patients who underwent RHC for soft tissue sarcoma at our Institution, 6 were enrolled into this study to... | ['Adult', 'Chemoradiotherapy', 'Dose Fractionation, Radiation', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'Humans', 'Hyperthermia, Induced', 'Male', 'Middle Aged', 'Salvage Therapy', 'Sarcoma', 'Treatment Outcome'] | 25,550,593 | [['M01.060.116'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['E02.815.639.200'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['M01.060.116.630'], ['E02.895'], ['C04.557.450.795'], ['E01.789... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel approach to the detection of genomic approximate tandem repeats in the Levenshtein metric. | An efficient algorithm for detecting approximate tandem repeats in genomic sequences is presented. The algorithm is based on innovative statistical criteria to detect candidate regions which may include tandem repeats; these regions are subsequently verified by alignments based on dynamic programming. No prior informat... | ['Algorithms', 'Animals', 'Base Sequence', 'Genome', 'Humans', 'Mathematics', 'Models, Genetic', 'Sequence Analysis, DNA', 'Tandem Repeat Sequences'] | 17,803,368 | [['G17.035', 'L01.224.050'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['E05.599.395.397'], ['E05.393.760.700'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', 'G05.360.340.024.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Direct alkylation of heteroaryls using potassium alkyl- and alkoxymethyltrifluoroborates. | A direct alkylation of various heteroaryls using stoichiometric potassium alkyl- and alkoxymethyltrifluoroborates has been developed. This method leads to the synthesis of complex substituted heterocycles, which have been obtained with yields up to 89%. | ['Alcohols', 'Alkylation', 'Borates', 'Fluorine Compounds', 'Free Radicals', 'Methylation', 'Molecular Structure', 'Potassium'] | 21,391,555 | [['D02.033'], ['G02.111.035', 'G02.607.094', 'G03.059'], ['D01.132.250.075', 'D01.248.497.158.076', 'D02.203.130.075'], ['D01.303'], ['D01.339', 'D02.389'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['G02.111.570', 'G02.466'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Scanning electrochemical microscopy determination of organic soluble MPC electron-transfer rates. | In this paper, we describe a novel method for measuring the forward heterogeneous electron-transfer rate constant (kf) through the thiol monolayer of gold monolayer protected clusters (MPCs) in solution using scanning electrochemical microscopy (SECM). Applying the equations for mixed mass-transfer and electron-transfe... | ['Electrochemistry', 'Electrons', 'Gold', 'Kinetics', 'Membranes, Artificial', 'Microscopy, Scanning Tunneling', 'Sensitivity and Specificity', 'Sulfhydryl Compounds', 'Surface Properties'] | 17,128,997 | [['H01.181.529.307'], ['G01.249.335', 'G01.358.500.750'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G01.374.661', 'G02.111.490'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E01.370.350.515.666.500', 'E05.595.666.500'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700',... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Effect of straw mulch and seeding rate on the harvest index, yield and water use efficiency of winter wheat. | Straw mulching has been used to improve water use efficiency (WUE, yield per unit evapotranspiration) in the Loess Plateau of China, but the seeding rate may need to be adjusted from conventional practice. We tested the three-way interaction between seeding rate, soil management (conventional tillage and straw mulching... | ['Agriculture', 'Biological Transport', 'Risk', 'Seeds', 'Soil', 'Temperature', 'Triticum', 'Water', 'Weather'] | 29,802,373 | [['J01.040'], ['G03.143'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Head injury and Parkinson's disease: a population-based study. | BACKGROUND: The epidemiological evidence on head injury and the risk of Parkinson's disease (PD) has been inconsistent.METHODS: We examined the relation between previous hospitalization for head injury and PD using a population-based nested case-control design based on the Swedish National Patient Register from 2001 un... | ['Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Community Health Planning', 'Craniocerebral Trauma', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Parkinson Disease', 'Retrospective Studies', 'Sweden'] | 23,143,933 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N03.349.650.185'], ['C10.900.300', 'C26.915.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: organ-specific distribution and variable induction patterns in mononuclear cells. | To investigate the expression of aryl hydrocarbon receptor repressor (AhRR) and related molecules in various tissues and the effects of aromatic hydrocarbons (AHs) on their expression, we developed a reliable technique of quantification of human AhRR as well as aryl hydrocarbon receptor (AhR), AhR nuclear translocator ... | ['Adult', 'Aryl Hydrocarbon Receptor Nuclear Translocator', 'Basic Helix-Loop-Helix Transcription Factors', 'Carcinogens', 'Cytochrome P-450 CYP1A1', 'DNA, Complementary', 'DNA-Binding Proteins', 'Dioxins', 'Female', 'Fetal Blood', 'Gene Expression Regulation', 'Humans', 'Infant, Newborn', 'Male', 'Methylcholanthrene',... | 14,672,759 | [['M01.060.116'], ['D12.776.157.530.750.100', 'D12.776.260.103.625.500', 'D12.776.543.585.750.100', 'D12.776.930.125.625.500'], ['D12.776.260.103', 'D12.776.930.125'], ['D27.888.569.100'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dihydropyridine-insensitive calcium currents contribute to function of small cerebral arteries. | Although dihydropyridines are widely used for the treatment of vasospasm, their effectiveness is questionable, suggesting that other voltage-dependent calcium channels (VDCCs) contribute to control of cerebrovascular tone. This study therefore investigated the role of dihydropyridine-insensitive VDCCs in cerebrovascula... | ['Animals', 'Calcium', 'Calcium Channel Blockers', 'Calcium Channels, L-Type', 'Calcium Channels, T-Type', 'Cell Membrane', 'Cerebral Arteries', 'Cerebrovascular Circulation', 'Dihydropyridines', 'Male', 'Myocytes, Smooth Muscle', 'Rats', 'Rats, Wistar', 'Vasoconstriction'] | 20,125,181 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['D12.776.157.530.400.150.720', 'D12.776.543.550.450.150.720', 'D12.776.543.585.400.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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