Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Generalized cognitive deficits in schizophrenia: a study of first-episode patients. | BACKGROUND: Cognitive impairment is recognized as a core characteristic of schizophrenia. There has always been a debate about the nature, selectivity, and time of onset of these deficits in relationship to the onset of illness and treatment factors. To our knowledge, the present study represents the largest sample of ... | ['Adult', 'Analysis of Variance', 'Cognition Disorders', 'Educational Status', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Parents', 'Schizophrenia', 'Schizophrenic Psychology', 'Severity of Illness Index', 'Social Class', 'Wechsler Scales'] | 10,435,610 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F03.615.250'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F03.700.750'], ['F04.824'], ['E05.318.308.980.438.475.456.500', 'N05.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Subcutaneous administration of a depot gonadotropin-releasing hormone agonist induces profound reproductive axis suppression in women. | OBJECTIVE: To compare the i.m. and s.c. routes of depot GnRH agonist administration.DESIGN: Prospective, controlled pharmacokinetics study.SETTING: Volunteers in an academic research environment.PATIENT(S): Forty women with benign gynecologic disorders.INTERVENTION(S): Triptorelin administration (3.75 mg) at 28-day int... | ['Adult', 'Estradiol', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Injections, Subcutaneous', 'Luteinizing Hormone', 'Progesterone', 'Reproduction', 'Triptorelin Pamoate'] | 9,531,874 | [['M01.060.116'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.620'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Grading Class I Preparations in Preclinical Dental Education: E4D Compare Software vs. the Traditional Standard. | The aim of this study was to compare the effectiveness of a novel assessment software system with the traditional grading protocol used in the University of Texas School of Dentistry at Houston operative dentistry preclinical curriculum. In the study, conducted in 2016, 98 Class I preparations were evaluated both tradi... | ['Clinical Competence', 'Dental Cavity Preparation', 'Education, Dental', 'Educational Measurement', 'Educational Technology', 'Humans', 'Software'] | 29,196,334 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E06.931.325'], ['I02.358.274'], ['I02.399'], ['J01.897.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Melioidosis presenting as an infected intrathoracic subclavian artery pseudoaneurysm treated with femoral vein interposition graft. | We present the first case of in situ replacement of an infected subclavian artery using superficial femoral vein and the fourth reported case of an infected arterial pseudoaneurysm caused by pseudomonas pseudomallei. Sepsis and hoarseness developed in a 58-year-old man after recent travel to Borneo, Indonesia. Indirect... | ['Aneurysm, False', 'Burkholderia pseudomallei', 'Coronary Artery Bypass', 'Diagnosis, Differential', 'Femoral Vein', 'Humans', 'Male', 'Melioidosis', 'Middle Aged', 'Subclavian Artery'] | 11,877,708 | [['C14.907.055.090'], ['B03.660.075.090.688.100.600'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.171'], ['A07.015.908.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.170.531'], ['M01.060.116.630'], ['A07.015.114.839']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Polyasplenia, caudal deficiency, and agenesis of the corpus callosum. | Fullana et al. [Am J Med Genet (suppl. 2): 23-29, 1986] reported on 2 sibs with an autosomal recessive syndrome of caudal deficiency and polyasplenia anomalies. We report on a similar patient in which agenesis of the corpus callosum (ACC) was also found. Such an association has not been reported previously. This findin... | ['Agenesis of Corpus Callosum', 'Female', 'Humans', 'Infant', 'Spine', 'Spleen'] | 2,012,140 | [['C10.500.034', 'C16.131.666.034', 'C23.300.008'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A02.835.232.834'], ['A10.549.700', 'A15.382.520.604.700']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
SIMULATION DIRECTORS AS IMPROVEMENT LEADERS. | Physician leaders who oversee simulation labs play vital roles in the advancement of efficiency and effectiveness of their organizations. | ['Adult', 'Delivery of Health Care', 'Female', 'Health Facility Administrators', 'Humans', 'Leadership', 'Male', 'Middle Aged', 'Practice Guidelines as Topic', 'Simulation Training', 'Staff Development'] | 30,571,895 | [['M01.060.116'], ['N04.590.374', 'N05.300'], ['M01.526.070.490', 'M01.526.485.430', 'N02.360.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['M01.060.116.630'], ['N04.761.700.350.650', 'N05.700.350.650'], ['I02.903.847'], ['I02.574.700', 'N04.452.677.822']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Inhibition of human plasma renin activity by pepstatin. | Pepstatin, a pentapeptide isolated from streptomyces, is a powerful inhibitor of several acid proteases. Its ability to inhibit the renin-angiotensinogen reaction was studied in vitro, in various human plasma. A 50% inhibition of plasma renin activity was obtained with 10(-6)M pepstatin at pH 5.7 and 10(-5)M at pH 7.4.... | ['Humans', 'Hydrogen-Ion Concentration', 'Hypertension', 'Kinetics', 'Oligopeptides', 'Pepstatins', 'Renin'] | 12,191 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['C14.907.489'], ['G01.374.661', 'G02.111.490'], ['D12.644.456'], ['D12.644.456.724'], ['D08.811.277.656.074.500.780', 'D08.811.277.656.300.048.780', 'D08.811.277.656.837.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential effect of assisted reproductive technology and small-for-gestational age on fetal cardiac remodeling. | OBJECTIVE: Fetuses conceived by assisted reproductive technology (ART) and those that are small-for-gestational age (SGA) show cardiovascular remodeling in utero; however, these two conditions are often associated. We aimed to evaluate the differential effect of ART and SGA on fetal cardiac remodeling.METHODS: This was... | ['Adult', 'Case-Control Studies', 'Cohort Studies', 'Echocardiography', 'Female', 'Fetal Heart', 'Humans', 'Infant, Newborn', 'Infant, Small for Gestational Age', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies', 'Reproductive Techniques, Assisted', 'Spain', 'Ultrasonography, Prenatal', 'Ventricular Remodeling'] | 27,420,642 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.541.278', 'A16.378.303'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pharmacodynamic and pharmacokinetic analysis of apoE4 [L261A, W264A, F265A, L268A, V269A], a recombinant apolipoprotein E variant with improved biological properties. | Physiological levels of wild-type (wt) apolipoprotein E (apoE) in plasma mediate the clearance of cholesterol-rich atherogenic lipoprotein remnants while higher than normal plasma apoE concentrations fail to do so and trigger hypertriglyceridemia. This property of wt apoE reduces significantly its therapeutic value as ... | ['Animals', 'Apolipoprotein E4', 'Base Sequence', 'Cells, Cultured', 'DNA Primers', 'Disease Models, Animal', 'Hypercholesterolemia', 'Mice', 'Mice, Knockout', 'Microscopy, Electron', 'Real-Time Polymerase Chain Reaction', 'Receptors, LDL', 'Recombinant Proteins'] | 22,985,620 | [['B01.050'], ['D10.532.091.500.750', 'D12.776.070.400.500.750', 'D12.776.521.120.500.750'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C18.452.584.500.500.396'], ['B01.050.150.900.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin ávâ3 via magnetic resonance imaging. | An understanding of neovascularization and/or angiogenesis in cancer is acutely required for effective cancer therapy due to concerns about tumor growth and metastasis. In particular, integrin ávâ3 is closely associated with cell migration and invasion during angiogenesis. Hence, we developed aptamer(ávâ3)-conjugated m... | ['Animals', 'Aptamers, Peptide', 'Contrast Media', 'Drug Delivery Systems', 'Humans', 'Integrin alphaVbeta3', 'Magnetic Fields', 'Magnetic Resonance Angiography', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Nanoparticles', 'Neoplasms, Experimental', 'Neovascularization, Pathologic', 'Radiography'] | 23,568,770 | [['B01.050'], ['D12.644.082'], ['D27.505.259.500', 'D27.720.259'], ['E02.319.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.625.439', 'D12.776.543.550.625.439', 'D12.776.543.750.705.408.460.870.500', 'D12.776.543.750.705.675.541'], ['G01.358.750'], ['E01.370.350.825.500.500', 'E01.370.370.050... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Induction of radioresistance by a nitric oxide-mediated bystander effect. | To elucidate whether nitric oxide secreted from irradiated cells affects cellular radiosensitivity, we examined the accumulation of inducible nitric oxide synthase, TP53 and HSP72, the concentration of nitrite in the medium of cells after X irradiation, and cellular radiosensitivity using two human glioblastoma cell li... | ['Cell Line', 'Coculture Techniques', 'Culture Media, Conditioned', 'HSP72 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Humans', 'Nitric Oxide', 'Nitric Oxide Donors', 'Penicillamine', 'Radiation Tolerance', 'Signal Transduction', 'Tumor Cells, Cultured', 'Tumor Suppressor Protein p53', 'X-Rays'] | 11,182,788 | [['A11.251.210'], ['E05.481.500.374'], ['D27.720.470.305.250', 'E07.206.250'], ['D12.776.580.216.375.202'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D27.505.519.656', 'D27.505.954.411.590'], ['D02.886.030.786', ... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo and in vitro bone strain in the owl monkey circumorbital region and the function of the postorbital septum. | Anthropoids and tarsiers are the only vertebrates possessing a postorbital septum. This septum, formed by the frontal, alisphenoid, and zygomatic bones, separates the orbital contents from the temporal muscles. Three hypotheses suggest that the postorbital septum evolved to resist stresses acting on the skull during ma... | ['Animals', 'Aotidae', 'Female', 'Male', 'Mastication', 'Models, Anatomic', 'Orbit', 'Stress, Mechanical'] | 8,893,085 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.037'], ['G07.203.650.283.500', 'G10.261.330.500'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['A02.835.232.781.324.690'], ['G01.374.835']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Differentiation of normal marrow and HL60 cells induced by antithymocyte globulin. | Antithymocyte globulin (ATG) therapy is an important treatment alternative for patients with acquired aplastic anemia. The mechanism by which it exerts its effects on hematopoiesis is unknown. In this report, we describe the ability of horse ATG to induce growth and differentiation of normal bone marrow. A single cell ... | ['Antilymphocyte Serum', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'Cells, Cultured', 'Humans', 'Kinetics', 'Leukemia, Myeloid, Acute', 'Macrophages', 'T-Lymphocytes', 'Tumor Stem Cell Assay'] | 3,875,092 | [['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['A11.148', 'A15.378.316'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['A11.251'], ['B01.050.150.900.649... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid design and implementation of an integrated patient self-triage and self-scheduling tool for COVID-19. | OBJECTIVE: To rapidly deploy a digital patient-facing self-triage and self-scheduling tool in a large academic health system to address the COVID-19 pandemic.MATERIALS AND METHODS: We created a patient portal-based COVID-19 self-triage and self-scheduling tool and made it available to all primary care patients at the U... | ['Academic Medical Centers', 'Adult', 'Appointments and Schedules', 'Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Diagnostic Self Evaluation', 'Humans', 'Medical Records Systems, Computerized', 'Pandemics', 'Patient Participation', 'Patient Portals', 'Pneumonia, Viral', 'SARS-CoV-2', 'San Francisco', 'Self ... | 32,267,928 | [['N02.278.020'], ['M01.060.116'], ['N04.452.095'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['E01.370.360', 'F01.752.747.792.220'], ['B01.050.150.9... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Differential distribution of gamma-glutamyl cycle molecules in the vomeronasal organ of rats. | Molecules related to the gamma-glutamyl cycle, including thiols, glutathione (GSH) and gamma-glutamyl transpeptidase (gamma-GT) were identified histochemically and immunohistochemically in the vomeronasal organ of neonatal and adult rats. Thiols and GSH were distributed in the mucomicrovillar complex (MMC), vomeronasal... | ['Aging', 'Animals', 'Animals, Newborn', 'Epithelial Cells', 'Epithelium', 'Glutathione', 'Nasal Septum', 'Neurons', 'Organ Specificity', 'Rats', 'Rats, Wistar', 'Sulfhydryl Compounds', 'gamma-Glutamyltransferase'] | 1,358,254 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['A11.436'], ['A10.272'], ['D12.644.456.448'], ['A04.531.591'], ['A08.675', 'A11.671'], ['G07.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D02.886.489'], ['D08.811.913.050.200.500']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Egg drop syndrome 76 in Nigeria: serological evidence in commercial farms. | A serological survey for egg drop syndrome 76 (EDS 76) virus, using the haemagglutination inhibition test, was conducted on commercial poultry flocks in Nigeria. Antibody was detected in layers on most of the farms. EDS 76 poses a potential threat to the Nigerian poultry industry and possible means of prevention and co... | ['Animals', 'Antibodies, Viral', 'Eggs', 'Female', 'Poultry', 'Poultry Diseases', 'Syndrome', 'Virus Diseases'] | 7,445,345 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G07.203.300.470', 'J02.500.470'], ['B01.050.050.116.625', 'B01.050.150.900.248.690', 'G07.203.300.600.750', 'J02.500.600.750'], ['C22.131.728'], ['C23.550.288.500'], ['C01.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The shear bond strength of porcelain and base metal alloys for metal-ceramic crown (VI)]. | The popularity of base metal alloy for porcelain fused to a metal crown and bridges has increased recently because of lower price, superior yield strength and modulus of elasticity (rigidity). The use of these alloys give them the potential advantage of thinner coping with less material and the required rigidity for lo... | ['Crowns', 'Dental Alloys', 'Dental Porcelain', 'Humans', 'Tensile Strength'] | 9,436,344 | [['E06.780.346.250', 'E07.695.190.088'], ['D25.339.208', 'J01.637.051.339.208'], ['D25.339.376', 'J01.637.051.339.376', 'J01.637.153.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Experimental studies on the effects of nocturnal noise on cortisol awakening response. | Cortisol awakening response (CAR), a considerable increase in cortisol concentrations post-awakening, is considered a reliable indicator of the reactivity of the hypothalamus-pituitary-adrenal axis (HPA). As noise has been shown to activate the HPA-axis, this analysis focuses on CAR as a possible indicator of noise-ind... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Noise, Transportation', 'Polysomnography', 'Railroads', 'Saliva', 'Sex Factors', 'Sleep', 'Wakefulness', 'Young Adult'] | 20,472,958 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['N06.230.400.550', 'N06.850.460.610.680'], ['E01.370.520.625'], ['J01.937.690'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Estimating the effect of childhood socioeconomic disadvantage on oral cancer in India using marginal structural models. | BACKGROUND: Early life socioeconomic disadvantage could affect adult health directly or indirectly. To the best of our knowledge, there are no studies of the direct effect of early life socioeconomic conditions on oral cancer occurrence in adult life.METHODS: We conducted a multicenter, hospital-based, case-control stu... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Case-Control Studies', 'Family Characteristics', 'Female', 'Humans', 'India', 'Life Change Events', 'Male', 'Middle Aged', 'Models, Statistical', 'Mouth Neoplasms', 'Occupations', 'Oropharyngeal Neoplasms', 'Smoking', 'Social Class', 'Tobacco Use', 'Young Adult'] | 25,989,249 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['F... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Intracranial haemorrhage detected by cerebral computed tomography after falls in hospital acute medical wards. | BACKGROUND: There is little published data on brain imaging and intracranial haemorrhage after hospital inpatient falls. Imaging protocols for inpatient falls have been adopted from head injury guidelines developed from data in patients presenting to the Emergency Department. We sought to describe the use of brain comp... | ['Accidental Falls', 'Aged', 'Aged, 80 and over', 'Australia', 'Female', 'Hospital Units', 'Hospitalization', 'Humans', 'Incidence', 'Intracranial Hemorrhages', 'Male', 'Retrospective Studies', 'Risk Factors', 'Tomography, X-Ray Computed'] | 31,684,952 | [['N06.850.135.122'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['N02.278.388'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of Progressive Relaxation Therapy among Orthopaedic Trauma Patients. | With urbanisation there has been phenomenal increase in mortality and morbidity due to orthopaedic trauma. Often the survivors are under much stress. In this study, it was therefore sought to assess the effectiveness of Progressive Relaxation Therapy among in-patients of orthopaedic ward of selected hospitals of Chenna... | ['Autogenic Training', 'Humans', 'India', 'Orthopedics', 'Relaxation Therapy', 'Wounds and Injuries'] | 30,650,940 | [['E02.190.525.217.100', 'F04.754.424.386'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['H02.403.810.494'], ['E02.190.525.875', 'F04.754.137.750'], ['C26']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Fluorescent Rhodamines and Fluorogenic Carbopyronines for Super-Resolution STED Microscopy in Living Cells. | A range of bright and photostable rhodamines and carbopyronines with absorption maxima in the range of ë=500-630 nm were prepared, and enabled the specific labeling of cytoskeletal filaments using HaloTag technology followed by staining with 1 ìm solutions of the dye-ligand conjugates. The synthesis, photophysical para... | ['Fluorescent Dyes', 'HeLa Cells', 'Humans', 'Microscopy', 'Pyronine', 'Rhodamines'] | 26,844,929 | [['D27.720.233.348', 'D27.720.470.410.505.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['D03.633.300.953.570'], ['D03.633.300.953.600']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Dose- and time-dependent formation of biliary benzo[a]pyrene metabolites in the marine flatfish dab (Limanda limanda). | Polycyclic aromatic hydrocarbons (PAHs) are abundant pollutants, and many PAHs are carcinogenic, but only after metabolic activation. Benzo[a]pyrene (BaP) is among the most carcinogenic PAHs. The dose and time response of two enzymes involved in BaP metabolism and the amounts of BaP metabolites excreted into the bile w... | ['Administration, Oral', 'Animals', 'Benzo(a)pyrene', 'Bile', 'Biomarkers', 'Carcinogens', 'Cytochrome P-450 CYP1A1', 'Dose-Response Relationship, Drug', 'Environmental Exposure', 'Environmental Monitoring', 'Flatfishes', 'Glutathione Transferase', 'Kinetics', 'Sensitivity and Specificity'] | 11,491,544 | [['E02.319.267.100'], ['B01.050'], ['D02.455.426.559.847.799.306.300', 'D04.615.799.306.300'], ['A12.200.087'], ['D23.101'], ['D27.888.569.100'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.220.453.010.332', 'D12.776.422.220.453.100.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Naked Mole-Rat mortality rates defy gompertzian laws by not increasing with age. | The longest-lived rodent, the naked mole-rat (Heterocephalus glaber), has a reported maximum lifespan of >30 years and exhibits delayed and/or attenuated age-associated physiological declines. We questioned whether these mouse-sized, eusocial rodents conform to Gompertzian mortality laws by experiencing an exponentiall... | ['Aging', 'Animals', 'Longevity', 'Mole Rats', 'Mortality'] | 29,364,116 | [['G07.345.124'], ['B01.050'], ['G07.345.124.519', 'G07.540'], ['B01.050.150.900.649.313.992.600'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of ionic contrast medium on plasma atrial natriuretic peptide. | To evaluate the effect of ionic contrast medium on plasma atrial natriuretic peptide (ANP) and its contributing factors, we measured plasma ANP, serum osmolality, pulmonary capillary wedge pressure (PCWP), femoral artery systolic pressure (FASP), and heart rate before and after left ventriculography with Rayvist in 13 ... | ['Adult', 'Aged', 'Atrial Natriuretic Factor', 'Contrast Media', 'Female', 'Humans', 'Iothalamic Acid', 'Male', 'Middle Aged', 'Osmolar Concentration', 'Radionuclide Ventriculography'] | 8,271,325 | [['M01.060.116'], ['M01.060.116.100'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.400.880.430', 'D02.455.426.559.389.127.375.880.430'], ['M01.060.116.630'], ['G02.640'], ['E01.370.350.130.937', 'E01.370.350.710.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. | 1. The effects of acute and subchronic nicotine and (+)-amphetamine on the extracellular levels of dopamine and its metabolites, dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in nucleus accumbens (NAc) have been studied in conscious, freely-moving rats by use of in vivo microdialysis. 2. In rats which ... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Dextroamphetamine', 'Dopamine', 'Homovanillic Acid', 'Male', 'Motor Activity', 'Nicotine', 'Nomifensine', 'Nucleus Accumbens', 'Rats', 'Rats, Inbred Strains'] | 1,504,716 | [['D02.241.223.601.220'], ['B01.050'], ['D02.092.471.683.152.110.200'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.241.223.601.521'], ['F01.145.632', 'G11.427.410.698'], ['D03.132.760.570', 'D03.383.725.518'], ['D03.633.100.531.535'], ['A08.186.211.200.885.287.249.487.775.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The antithrombotic treatment and prevention of recurrence with acetylsalicylic acid in myocardial infarct]. | A comparison of the therapy, especially of the long-term recidivation prophylaxis of the myocardial infarction with acetyl salicylic acid and anticoagulants, on the basis of 314 observations allows of the following opinions: By means of the thrombocyte aggregation inhibitor acetyl salicylic acid an antithrombotic thera... | ['Animals', 'Anticoagulants', 'Aspirin', 'Dogs', 'Drug Hypersensitivity', 'Gastrointestinal Hemorrhage', 'Humans', 'Myocardial Infarction', 'Rabbits', 'Recurrence', 'Thrombosis', 'Urticaria'] | 1,085,534 | [['B01.050'], ['D27.505.954.502.119'], ['D02.455.426.559.389.657.410.595.176'], ['B01.050.150.900.649.313.750.250.216.200'], ['C20.543.206', 'C25.100.468'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Barriers to insulin initiation: the translating research into action for diabetes insulin starts project. | OBJECTIVE: Reasons for failing to initiate prescribed insulin (primary nonadherence) are poorly understood. We investigated barriers to insulin initiation following a new prescription.RESEARCH DESIGN AND METHODS: We surveyed insulin-na?ve patients with poorly controlled type 2 diabetes, already treated with two or more... | ['Diabetes Mellitus, Type 2', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Medication Adherence'] | 20,086,256 | [['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['F01.100.150.750.500.600.500', 'F01.145.488.887.500.600.500', 'N05.300.150.800.500.600.500']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hippocampal volume in aging combat veterans with and without post-traumatic stress disorder: relation to risk and resilience factors. | OBJECTIVE: To examine whether there are post-traumatic stress disorder (PTSD) related differences in hippocampal volume in middle-aged and elderly veterans and to examine the relationship of neuroendocrine activity, memory performance, and measures of risk and resilience for PTSD to hippocampal volume in this cohort.ME... | ['Aged', 'Aged, 80 and over', 'Aging', 'Chronic Disease', 'Female', 'Hippocampus', 'Humans', 'Hydrocortisone', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Risk Factors', 'Stress Disorders, Post-Traumatic', 'Veterans', 'Warfare', 'Wechsler Scales'] | 16,445,942 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C23.550.291.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E01.370.350.825.500'], ['M01.060.116.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Behaviour of Lutzomyia longipalpis in an area of southern Honduras endemic for visceral/atypical cutaneous leishmaniasis. | The predominant sandfly in Las Maria de Pavana, Choluteca, Honduras, was found to be Lutzomyia longipalpis, most (69%) of the 791 specimens of this species caught being male. When local Lu. longipalpis were studied over 1 year (1986-1987) using CDC traps, peaks in the size of the adult population were observed in Decem... | ['Animals', 'Behavior, Animal', 'Endemic Diseases', 'Female', 'Honduras', 'Horses', 'Humans', 'Insect Vectors', 'Leishmaniasis, Cutaneous', 'Leishmaniasis, Visceral', 'Male', 'Psychodidae', 'Seasons', 'Sex Distribution', 'Swine'] | 10,396,347 | [['B01.050'], ['F01.145.113'], ['N06.850.392'], ['Z01.107.169.534'], ['B01.050.150.900.649.313.984.235.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.813.400', 'C17.800.838.775.560.400'], ['C... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
High frequency of low-virulent microorganisms detected by sonication of pedicle screws: a potential cause for implant failure. | OBJECTIVE: Loosening of pedicle screws is a frequent complication after spinal surgery. Implant colonization with low-virulent microorganisms forming biofilms may cause implant loosening. However, the clinical evidence of this mechanism is lacking. Here, the authors evaluated the potential role of microbial colonizatio... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Pedicle Screws', 'Postoperative Complications', 'Prosthesis Failure', 'Sonication', 'Spinal Fusion', 'Tomography, X-Ray Computed'] | 31,137,006 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E07.695.370.437.500', 'E07.858.442.660.460.437.500', 'E07.858.690.725.460.437.500'], ['C23.550.767'], ['C23.550.767.865', 'E05.325.771'], ['E05.848'], ['E04.55... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bedside Ultrasound Reduces Diagnostic Uncertainty and Guides Resuscitation in Patients With Undifferentiated Hypotension. | OBJECTIVES: Utilization of ultrasound in the evaluation of patients with undifferentiated hypotension has been proposed in several protocols. We sought to assess the impact of an ultrasound hypotension protocol on physicians' diagnostic certainty, diagnostic ability, and treatment and resource utilization.DESIGN: Prosp... | ['Aged', 'Blood Pressure', 'Blood Transfusion', 'Cardiovascular Agents', 'Clinical Protocols', 'Critical Care', 'Diagnosis, Differential', 'Emergency Service, Hospital', 'Female', 'Fluid Therapy', 'Humans', 'Hypotension', 'Length of Stay', 'Male', 'Middle Aged', 'Point-of-Care Systems', 'Prospective Studies', 'Resuscit... | 26,575,653 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E02.095.135'], ['D27.505.954.411'], ['E02.183', 'N05.715.360.330.125'], ['E02.760.190', 'N02.421.585.190'], ['E01.171'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E02.319.360'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
How can educators support general practice (GP) trainees to develop resilience to prevent burnout? | CONTEXT: Burnout impacts adversely on professional and personal life, and holds implications for patient care. Current research on burnout mainly focuses on established general practitioners but it is unclear how early the signs of burnout really start. This work seeks to identify whether specific GP trainee groups are... | ['Burnout, Professional', 'Cohort Studies', 'Family Characteristics', 'Female', 'General Practitioners', 'Humans', 'Longitudinal Studies', 'Male', 'Resilience, Psychological', 'Surveys and Questionnaires', 'United Kingdom', 'Workload'] | 27,684,963 | [['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['M01.526.485.810.485', 'N02.360.810.485'], ['B01.050.150.900... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
General dentists and pediatric dental patients: the role of dental education. | The objective of this study was to investigate whether undergraduate dental education affects general dentists' practice characteristics, attitudes, and professional behavior concerning the treatment of pediatric patients. Data were collected with a self-administered mailed survey from 241 general dentists who were mem... | ['Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Dental Care for Children', 'General Practice, Dental', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Michigan', 'Middle Aged', "Practice Patterns, Dentists'", 'Surveys and Questionnaires'] | 17,170,321 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E06.170.152', 'N02.421.240.190.215'], ['H02.163.342'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.500', 'Z01.107.567.875.510.500'], ['M01.060.116.630'], ['N04.590.374.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Quantifying the mechanism of phosphate monoester hydrolysis in aqueous solution by evaluating the relevant ab initio QM/MM free-energy surfaces. | Understanding the nature of the free-energy surfaces for phosphate hydrolysis is a prerequisite for understanding the corresponding key chemical reactions in biology. Here, the challenge has been to move to careful ab initio QM/MM (QM(ai)/MM) free-energy calculations, where obtaining converging results is very demandin... | ['Esters', 'Hydrolysis', 'Ions', 'Kinetics', 'Magnesium', 'Models, Molecular', 'Phosphates', 'Quantum Theory', 'Solutions', 'Surface Properties', 'Thermodynamics', 'Water'] | 23,601,038 | [['D02.241.400'], ['G02.380'], ['D01.248.497'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.599.595'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['H01.671.579.800'], ['D26.776'], ['G02.860'], ['G01.906'], ['D01.045.250.875', 'D01.248.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mean Platelet Volume in Heterozygous Beta Thalassaemia. | BACKGROUND/AIM: It is not known why cerebrovascular and cardiovascular ischaemic events are less frequently observed in heterozygous beta thalassaemia (HBT) patients than in the general population. However, we previously reported that serum levels of some platelet function markers, i.e. soluble CD40 ligand and soluble ... | ['Adolescent', 'Adult', 'Aged', 'CD40 Ligand', 'Cross-Sectional Studies', 'Humans', 'Mean Platelet Volume', 'Middle Aged', 'P-Selectin', 'beta-Thalassemia'] | 28,208,125 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Photodynamic therapy as palliation for esophageal cancer: experience in 215 patients. | BACKGROUND: Photodynamic therapy (PDT) utilizes a photosensitizing agent, light, and oxygen to endoscopically ablate cancer cells. This review summarizes our experience with PDT for the palliation of bleeding or obstructing esophageal cancer (EC).METHODS: All patients with bleeding or obstructing EC treated with PDT fr... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Dihematoporphyrin Ether', 'Esophageal Neoplasms', 'Esophagoscopy', 'Female', 'Humans', 'Injections, Intralesional', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Palliative Care', 'Photochemotherapy', 'Prognosis', 'Retrospective Studies', 'Risk Assessment', 'Survi... | 14,602,313 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.129.578.840.500.462.400.200', 'D03.633.400.909.500.462.400.200', 'D04.345.783.500.462.400.200', 'D23.767.727.462.400.200'], ['C04.588.274.476.205', 'C04.588.443.353', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The parasite fauna of East Germany. 9. The helminth fauna of Lutra lutra]. | Alimentary tract, liver, kidneys and lungs of 25 otters, died of several causes during 1982-1987 in GDR were included in helminthological investigations. Parasites were detected in 8 animals. One cestode: Taenia martis and 3 trematodes: Isthmiophora melis, Opisthorchis felineus and Pseudamphistomum truncatum are regard... | ['Animals', 'Carnivora', 'Cestode Infections', 'Germany, East', 'Helminthiasis', 'Helminthiasis, Animal', 'Otters', 'Trematode Infections'] | 3,177,936 | [['B01.050'], ['B01.050.150.900.649.313.750'], ['C01.610.335.190'], ['Z01.586.338'], ['C01.610.335'], ['C01.610.335.349', 'C01.610.701.377', 'C22.674.377'], ['B01.050.150.900.649.313.750.250.575.600'], ['C01.610.335.865']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Hematopoietic stem cell transplantation protects mice from lethal stroke. | Stroke is a major cause of mortality and morbidity in the United States. The ideal therapeutic approach would minimize cell death and regenerate brain tissue. In order to investigate some questions that are related to such an approach, we have generated a mouse model in which we induce a stroke using the middle cerebra... | ['Animals', 'Hematopoietic Stem Cell Transplantation', 'Immunohistochemistry', 'Mice', 'Stroke'] | 20,547,154 | [['B01.050'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['B01.050.150.900.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical validation of the Psychotic Depression Assessment Scale (PDAS) against independent global severity ratings in older adults. | OBJECTIVES: According to a recent study, ratings on the Psychotic Depression Assessment Scale (PDAS) obtained via a dedicated semi-structured interview are valid measures of the severity of psychotic depression. This study aimed to further test the validity, scalability and responsiveness of the PDAS in older adults us... | ['Aged', 'Aged, 80 and over', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Psychotic Disorders', 'Reproducibility of Results', 'Severity of Illness Index'] | 29,501,075 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513.653'], ['F04.711.780'], ['F03.700.675'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of feedback on obstetrics and gynecology residents' teaching performance and attitudes. | OBJECTIVE: To evaluate obstetrics and gynecology residents' teaching performance, perception of the importance of teaching and satisfaction with their evaluations after the institution of an oral or written medical student feedback and award system.STUDY DESIGN: Residents at a single, university-based obstetrics and gy... | ['Attitude of Health Personnel', 'Humans', 'Internship and Residency', 'Obstetrics and Gynecology Department, Hospital', 'Prospective Studies', 'Surveys and Questionnaires', 'Teaching'] | 11,499,187 | [['F01.100.050', 'N05.300.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['N02.278.216.500.968.495', 'N04.452.442.452.422.495'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.308.980', 'N05.715.360.300.800', ... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[In vitro and in vivo studies of RNAse of Bacillus intermedius]. | Cytotoxicity of RNAase from Bacillus intermedius was studied in vitro and in vivo. It was shown that the enzyme had slightly pronounced cytotoxicity according to the tests with inhibition of cell proliferation and biosynthesis of cell nucleic acids. The RNAase was also shown to impair the vital staining by neutral red.... | ['Amnion', 'Animals', 'Antineoplastic Agents', 'Bacillus', 'Cell Division', 'Culture Media', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'In Vitro Techniques', 'Leukemia, Experimental', 'Leukemia, Lymphoid', 'Mice', 'Ovarian Neoplasms', 'Ribonuclease, Pancreatic', 'Ribonucleases'] | 2,751,384 | [['A10.615.284.277', 'A16.254.750.277'], ['B01.050'], ['D27.505.954.248'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D27.720.470.305', 'E07.206'], ['G07.690.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of the PTPN22 R620W polymorphism with anti-topoisomerase I- and anticentromere antibody-positive systemic sclerosis. | OBJECTIVE: To determine any associations of the PTPN22 R620W single-nucleotide polymorphism (SNP) with systemic sclerosis (SSc) or with anticentromere antibody (ACA)-positive or anti-topoisomerase I (anti-topo I) antibody-positive SSc, in a case-control study of US white, black, Hispanic, and Choctaw Indian individuals... | ['Autoantibodies', 'Centromere', 'Continental Population Groups', 'DNA Topoisomerases, Type I', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Odds Ratio', 'Polymorphism, Single Nucleotide', 'Protein Tyrosine Phosphatase, Non-Receptor Type 22', 'Protein Tyrosine Phosphatases', 'Risk Facto... | 17,133,608 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['M01.686.508'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The impact of visceral fat accumulation on laparoscopy-assisted distal gastrectomy for early gastric cancer. | BACKGROUND: Laparoscopy-assisted distal gastrectomy (LADG) has been widely accepted for the treatment for early gastric cancer. Obesity is a rapidly growing epidemic, and the number of obese patients with gastric cancer is increasing, but the impact of visceral fat (VF) accumulation on laparoscopic gastric surgery rema... | ['Blood Loss, Surgical', 'C-Reactive Protein', 'Chi-Square Distribution', 'Gastrectomy', 'Humans', 'Intra-Abdominal Fat', 'Laparoscopy', 'Length of Stay', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Stomach Neoplasms', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 19,215,214 | [['C23.550.414.300', 'C23.550.505.300'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.165.114.830.500.500'], ['E01.370.388.250.520',... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Observing middle and inner ear mechanics with novel intracochlear pressure sensors. | Intracochlear pressure was measured in vivo in the base of the gerbil cochlea. The measurements were made over a wide range of frequencies simultaneously in scalae vestibuli and tympani. Pressure was measured just adjacent to the stapes in scala vestibuli and at a number of positions spaced by tens of micrometers, incl... | ['Acoustic Impedance Tests', 'Animals', 'Basilar Membrane', 'Gerbillinae', 'Organ of Corti', 'Tympanic Membrane'] | 9,637,031 | [['E01.370.382.375.050'], ['B01.050'], ['A09.246.300.246.125', 'A10.615.179.124'], ['B01.050.150.900.649.313.992.635.300'], ['A09.246.300.246.577'], ['A09.246.272.702']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interhospital transfer of cardiac patients: does air transport make a difference? | INTRODUCTION: The purpose of this study was to compare the outcome of interhospital transported cardiac patients for whom bias in selecting transport mode was removed due to helicopter unavailability.METHODS: Patients with the diagnosis of unstable angina or myocardial infarction who underwent transport by ground only ... | ['Air Ambulances', 'Ambulances', 'Angina, Unstable', 'Bias', 'Cardiology Service, Hospital', 'Case-Control Studies', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Medical Audit', 'Middle Aged', 'Myocardial Infarction', 'North Carolina', 'Transportation of Patients', 'Treatment Outcome', 'Triage'] | 10,133,648 | [['J01.937.285.100.100', 'N02.421.297.879.100.100'], ['J01.937.500.050', 'N02.421.297.879.100'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['N05.715.350.150', 'N06.850.490.500'], ['N02.278.216.500.968.215', 'N04.452.442.452.422.215'], ['E05.318.372.500.500', 'N05.715.360.330.500.500... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Network effects on coordination in asymmetric games. | Network structure can have an important effect on the behavior of players in an iterated 2 ? 2 game. We study the effect of network structure on global and local behavior in asymmetric coordination games using best response dynamics. We find that global behavior is highly dependent on network topology. Random (Erd?s-R?... | ['Algorithms', 'Computer Simulation', 'Cooperative Behavior', 'Game Theory', 'Humans', 'Models, Theoretical'] | 29,208,965 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['F01.145.813.115'], ['G17.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of levodopa on motor sequence learning in Parkinson's disease. | BACKGROUND: Dopaminergic therapy with levodopa improves motor function in PD patients, but the effects of levodopa on cognition in PD remain uncertain.OBJECTIVE: To use H(2)(15)O and PET to assess the effect of levodopa infusion on motor sequence learning in PD.METHODS: Seven right-handed PD patients were scanned "on" ... | ['Aged', 'Antiparkinson Agents', 'Brain', 'Cognition', 'Dopamine Agents', 'Female', 'Humans', 'Learning', 'Levodopa', 'Male', 'Middle Aged', 'Parkinson Disease', 'Psychomotor Performance', 'Tomography, Emission-Computed'] | 12,796,524 | [['M01.060.116.100'], ['D27.505.954.427.090.050'], ['A08.186.211'], ['F02.463.188'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D12.125.072.050.685.400.500', 'D12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
3 fraction pencil-beam scanning proton accelerated partial breast irradiation: early provider and patient reported outcomes of a novel regimen. | BACKGROUND AND PURPOSE: To report dosimetry and early adverse effects, aesthetic, and patient-reported outcomes of a prospective study of 3-fraction pencil-beam scanning (PBS) proton accelerated partial irradiation (APBI).MATERIALS AND METHODS: Eligibility included women age ? 50 years with estrogen receptor positive (... | ['Aged', 'Aged, 80 and over', 'Breast', 'Breast Neoplasms', 'Dose Fractionation, Radiation', 'Estrogen Receptor alpha', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Middle Aged', 'Patient Reported Outcome Measures', 'Prospective Studies', 'Proton Therapy', 'Protons', 'Quality of Life', 'Radiometry', 'Radiotherapy... | 31,752,934 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E02.815.639.200'], ['D12.776.826.750.350.174'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.116.630'], ['E05.318.308.980.344.500', 'N03.349.380.210.750', 'N04.761.559.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Septic thrombosis of cavernous sinus extended to the ipsilateral internal jugular vein and transversal sinus with favorable outcome: Clinical and radiological features of a Lemierre syndrome. | An 86-year-old patient was hospitalized for fever and left acute orbital syndrome (red eye with moderate visual impairment, chemosis, ophthalmoplegia without proptosis, or any fundus involvement). CT scan showed superior ophthalmic vein and cavernous sinus enlargement complicating ipsilateral sphenoidal sinusitis. Magn... | ['Aged, 80 and over', 'Anti-Bacterial Agents', 'Anticoagulants', 'Cavernous Sinus Thrombosis', 'Humans', 'Jugular Veins', 'Lemierre Syndrome', 'Magnetic Resonance Imaging', 'Male', 'Paranasal Sinus Diseases', 'Staphylococcal Infections', 'Staphylococcus', 'Streptococcal Infections', 'Streptococcus intermedius', 'Tomogr... | 29,040,036 | [['M01.060.116.100.080'], ['D27.505.954.122.085'], ['D27.505.954.502.119'], ['C10.228.140.300.525.425.500.375', 'C14.907.253.566.350.500.375', 'C14.907.355.590.213.350.500.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.908.498'], ['C01.150.252.400.388.350.700', 'C07.550.174', 'C09.775.262', 'C14.907.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bone marrow cell content and osteoclasts in crista biopsies. | The bone marrow cell content was investigated by counting the percentage of cells in the areas between the trabeculae in crista biopsies. There was a decrease in the percentage of cells in bone marrow in osteoporotic women compared with our normal material. In patients undergoing haemodialysis there was a positive corr... | ['Alcoholism', 'Biopsy', 'Bone Marrow', 'Cell Count', 'Female', 'Humans', 'Ilium', 'Male', 'Osteoclasts', 'Osteoporosis', 'Renal Dialysis'] | 7,446,019 | [['C25.775.100.250', 'F03.900.100.350'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A15.382.216'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations. | Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is a high-risk subgroup of T-lineage ALL characterized by specific stem cell and myeloid features. In adult ETP-ALL, no comprehensive studies on the genetic background have been performed to elucidate molecular lesions of this distinct subgroup. We perform... | ['Adolescent', 'Adult', 'Aged', 'Biomarkers, Tumor', 'DNA (Cytosine-5-)-Methyltransferases', 'Epigenesis, Genetic', 'Exome', 'Female', 'Follow-Up Studies', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Precursor Cells, T-Lymphoid', 'Precursor T-Cell Lymphoblastic Leukemia-Lympho... | 23,603,912 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['D08.811.913.555.500.350.100.500'], ['G05.308.203'], ['G05.360.340.011'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Sustained ventricular tachycardia in postinfarct ischemic heart disease: spontaneous polymorphism. Clinical, therapeutic and prognostic aspects]. | UNLABELLED: Spontaneous Polymorphism (SP) is present when at least two episodes of Sustained Ventricular Tachycardia (SVT) occur spontaneously in the same patient (pt) with different bundle branch block pattern or with shifting of QRS axis by greater than or equal to 90 in the various episodes. We undertook this study ... | ['Adult', 'Aged', 'Amiodarone', 'Coronary Disease', 'Electrocardiography', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prognosis', 'Tachycardia'] | 4,007,367 | [['M01.060.116'], ['M01.060.116.100'], ['D03.633.100.127.075'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Determination of patient preference for location of elective abdominal aortic aneurysm surgery. | OBJECTIVE: Aneurysm repair is centralized in higher volume centers resulting in reduced mortality, with longer travel distances. The purpose of this study is to explore patients' preference between local care versus longer distances and lower mortality rates.METHODS: Patients with abdominal aortic aneurysm (AAA) measur... | ['Aged', 'Aortic Aneurysm, Abdominal', 'Catchment Area, Health', 'Elective Surgical Procedures', 'Female', 'Health Care Surveys', 'Health Services Accessibility', 'Hospitals, High-Volume', 'Hospitals, Low-Volume', 'Humans', 'Male', 'Ontario', 'Outcome and Process Assessment, Health Care', 'Patient Preference', 'Quality... | 23,579,366 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['E04.249'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['N02.278.421.414'], ... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Recognition of emotional prosody by Mandarin-speaking adults with cochlear implants. | To understand how cochlear implant processing affects emotional prosody recognition in tonal languages, how normal-hearing (NH) and cochlear-implanted (CI) adults identify four emotions ("angry," "happy," "sad," and "neutral") in short, semantically neutral, Mandarin sentences are compared. Depending on hearing status ... | ['Adult', 'Asian Continental Ancestry Group', 'Cochlear Implants', 'Emotions', 'Female', 'Hearing Loss', 'Humans', 'Male', 'Phonetics', 'Semantics', 'Speech Acoustics', 'Speech Perception'] | 31,472,572 | [['M01.060.116'], ['M01.686.508.200'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['F01.470'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.518'], ['L01.559.598.745'], ['G11.561.81... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Predictors of mortality after short-term ventricular assist device placement. | BACKGROUND: Risk assessment prior to long-term ventricular assist device (VAD) placement has been shown to be crucial for successful outcomes and efficient resource utilization. Short-term VADs are often used as salvage therapy in acute heart failure when the clinical scenario precludes such thorough preoperative asses... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Female', 'Heart Failure', 'Heart-Assist Devices', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Risk Assessment', 'Time Factors', 'Young Adult'] | 22,051,257 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['C14.280.434'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Renal revascularization in the azotemic hypertensive patient resistant to therapy. | We undertook this study to assess the frequency of renovascular hypertension in patients with azotemia and hypertension refractory to drug therapy and to determine the effects of renal revascularization on blood pressure and renal function in these subjects. Thirty-nine of 106 consecutive patients admitted for diagnost... | ['Aged', 'Angioplasty, Balloon', 'Blood Pressure', 'Drug Resistance', 'Female', 'Follow-Up Studies', 'Humans', 'Hypertension, Renovascular', 'Kidney', 'Male', 'Middle Aged', 'Renal Artery', 'Uremia'] | 6,237,260 | [['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.984'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of aerobic dance on cardiorespiratory fitness in pregnant women: a randomised controlled trial. | OBJECTIVE: To evaluate the effectiveness of aerobic dance on cardiorespiratory fitness in pregnant women.DESIGN: Randomised controlled trial.PARTICIPANTS: Sixty-two primiparous women with a mean age of 30.6 [standard deviation (SD) 3.7] years randomised to exercise (n=34) and (n=28) control groups.INTERVENTION: Two aer... | ['Adult', 'Case-Control Studies', 'Chi-Square Distribution', 'Dancing', 'Exercise Test', 'Female', 'Humans', 'Lactates', 'Norway', 'Oxygen Consumption', 'Physical Fitness', 'Pregnancy', 'Treatment Outcome'] | 23,186,730 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['I03.450.642.287'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Quality-assuring intervention for technical medical staff at medical committees. | PURPOSE: This paper seeks to examine an intervention program which was developed in order to improve the performance and skills of technical medical personnel at the military recruitment medical committees.DESIGN/METHODOLOGY/APPROACH: Evaluation of the technician soldiers' performance was carried out by the usage of a ... | ['Blood Pressure', 'Clinical Competence', 'Health Knowledge, Attitudes, Practice', 'Health Personnel', 'Humans', 'Israel', 'Military Personnel', 'Physical Examination', 'Quality Assurance, Health Care', 'Urinalysis', 'Vision Tests'] | 21,456,495 | [['E01.370.600.875.249', 'G09.330.380.076'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F01.100.150.500', 'N05.300.150.410'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['M01.526.625'], ['E01.370.600'], ['N04.761.700', 'N05.700'], ['E01.370.225.124.81... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates. | Protein sumoylation is a regulated process that is important for the health of human and yeast cells. In budding yeast, a subset of sumoylated proteins is targeted for ubiquitination by a conserved heterodimeric ubiquitin (Ub) ligase, Slx5-Slx8, which is needed to suppress the accumulation of high molecular weight smal... | ['DNA-Binding Proteins', 'Mutation', 'Proteasome Endopeptidase Complex', 'Protein Binding', 'Repressor Proteins', 'SUMO-1 Protein', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Small Ubiquitin-Related Modifier Proteins', 'Substrate Specificity', 'Ubiquitin-Protein Ligases'] | 18,499,666 | [['D12.776.260'], ['G05.365.590'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['G02.111.679', 'G03.808'], ['D12.776.260.703', 'D12.776.930.780'], ['D12.776.947.249.500'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['D12.776.947.249'], ['G02.111.835'], ['D08.811.464.938.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subchronic inhalation study of stone wool fibres in rats. | Pathology results after subchronic inhalation in rats of three separate fibres representing the new biosoluble high-aluminium low-silica HT type stone wool are given, and the results were compared with the results from a similar study done with the traditional stone wool MMVF21. Male Wistar rats were exposed at one exp... | ['Administration, Inhalation', 'Aluminum', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Lung Diseases', 'Male', 'Mineral Fibers', 'Models, Animal', 'Occupational Diseases', 'Particle Size', 'Rats', 'Rats, Wistar', 'Silicon Dioxide', 'Solubility', 'Time Factors'] | 14,990,431 | [['E02.319.267.050'], ['D01.268.557.050', 'D01.552.547.050'], ['B01.050'], ['E05.927.100.500'], ['C08.381'], ['D01.578.500'], ['E05.598'], ['C24'], ['G02.712'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['G02.805'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of concentration, pH, and preservative on in vitro transcorneal permeation of ibuprofen and flurbiprofen from non-buffered aqueous drops. | Influence of drug concentration, pH of aqueous drops and some commonly used preservatives on in vitro transcorneal permeation of ibuprofen and flurbiprofen were investigated using goat cornea. Increase in drug concentration in the drops made in normal saline resulted in increase in quantity permeated but decrease in cu... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Buffers', 'Cornea', 'Flurbiprofen', 'Goats', 'Hydrogen-Ion Concentration', 'Ibuprofen', 'Ophthalmic Solutions', 'Permeability', 'Preservatives, Pharmaceutical', 'Water'] | 9,475,059 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.720.470.280'], ['A09.371.060.217'], ['D02.241.081.751.161', 'D02.455.426.559.389.185.350'], ['B01.050.150.900.649.313.500.380.513'], ['G02.300'], ['D02.241.223.701.430'], ['D26.776.708.645', 'D27.505.954.578.645', 'D2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trypanosoma cruzi: parasite persistence in tissues in chronic chagasic Brazilian patients. | Chagas disease in the chronic phase may develop into cardiac and/or digestive forms. The pathogenesis of the disease is not yet clear and studies have been carried out to elucidate the role of parasite persistence in affected organs. The aim of this study was to detect and quantify Trypanosoma cruzi in paraffin-embedde... | ['Chagas Disease', 'DNA, Protozoan', 'Gastrointestinal Tract', 'Heart', 'Humans', 'Polymerase Chain Reaction', 'Trypanosoma cruzi'] | 21,340,361 | [['C01.610.752.300.900.200', 'C01.920.625'], ['D13.444.308.442'], ['A03.556'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500'], ['B01.268.475.868.887.140']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Common carotid intima-media thickness and lower extremity arterial atherosclerosis. The Rotterdam Study. | High-resolution B-mode ultrasonography of the carotid arteries is used to investigate the signs of early atherosclerotic vessel wall disease. To assess whether carotid artery findings reflect atherosclerosis elsewhere, we studied the association between common carotid intima-media thickness and lower extremity arterial... | ['Aged', 'Arteriosclerosis', 'Carotid Artery Diseases', 'Carotid Artery, Common', 'Female', 'Follow-Up Studies', 'Humans', 'Intermittent Claudication', 'Leg', 'Linear Models', 'Male', 'Middle Aged', 'Prospective Studies', 'Risk Factors', 'Tunica Intima', 'Ultrasonography'] | 7,981,175 | [['M01.060.116.100'], ['C14.907.137.126'], ['C10.228.140.300.200', 'C14.907.253.123'], ['A07.015.114.186.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.137.126.669', 'C23.888.531'], ['A01.378.610.500'], ['E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Analysis of peptides associated with class II MHC molecules, HLA-DR3: implication for the prediction of peptides useful for vaccines]. | In order to characterize peptide binding motifs of MHC class II molecules HLA-DR3, we have sequenced pool or single peptides eluted from the binding groove. Anchor residues identified are in agreement with peptide binding and sequencing studies reported by different groups. Four positions seem to be dominant (i, i + 3,... | ['Amino Acid Sequence', 'Animals', 'Antigens, Helminth', 'Chromatography, High Pressure Liquid', 'Epitopes', 'HLA-DR3 Antigen', 'Histocompatibility Antigens Class II', 'In Vitro Techniques', 'Schistosoma mansoni', 'Sequence Alignment', 'Sequence Analysis', 'Vaccines'] | 9,091,183 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.223'], ['E05.196.181.400.300'], ['D23.050.550'], ['D12.776.395.550.509.400.440.400.030', 'D12.776.543.550.440.400.440.400.030', 'D23.050.301.500.400.400.440.400.030', 'D23.050.301.500.450.400.440.389.875', 'D23.050.705.552.410.400.440.389.030', 'D23.05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Functional criticality in the human brain: Physiological, behavioral and neurodevelopmental correlates. | Understanding the critical features of the human brain at multiple time scales is vital for both normal development and disease research. A recently proposed method, the vertex-wise Index of Functional Criticality (vIFC) based on fMRI, has been testified as a sensitive neuroimaging marker to characterize critical trans... | ['Adolescent', 'Adult', 'Aged', 'Anxiety', 'Behavior', 'Brain', 'Brain Mapping', 'Cerebral Cortex', 'Cross-Sectional Studies', 'Databases, Factual', 'Female', 'Healthy Volunteers', 'Heart Rate', 'Humans', 'Image Processing, Computer-Assisted', 'Longevity', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuroimag... | 30,849,117 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.470.132'], ['F01.145'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.313.500.750.300.188.400'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Cell-printed 3D liver-on-a-chip possessing a liver microenvironment and biliary system. | To overcome the drawbacks of in vitro liver testing during drug development, numerous liver-on-a-chip models have been developed. However, current liver-on-a-chip technologies are labor-intensive, lack extracellular matrix (ECM) essential for liver cells, and lack a biliary system essential for excreting bile acids, wh... | ['Acetaminophen', 'Biliary Tract', 'Cellular Microenvironment', 'Cytochrome P-450 Enzyme System', 'Gene Expression Regulation', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Inactivation, Metabolic', 'Lab-On-A-Chip Devices', 'Liver', 'Liver Function Tests', 'Organ Specificity', 'Printing, Three-Dimensional'] | 30,566,930 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['A03.159'], ['G04.366'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G05.308'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.171.450', 'G03.787.225.450', 'G07.690.725.225.450'], ['E07.305.343.500'], ['A03.620']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Regulation of P450c17 expression in the early embryo depends on GATA factors. | The enzyme P450c17 is required for glucocorticoid, sex steroid, and some neurosteroid biosynthesis. Defective human P450c17 causes sexual infantilism and 46,XY sex reversal but is compatible with life, whereas ablation of the corresponding mouse gene causes embryonic lethality at around E7. Normal mouse embryos express... | ['Animals', 'Base Sequence', 'Binding Sites', 'Cells, Cultured', 'Embryo, Mammalian', 'GATA Transcription Factors', 'GATA4 Transcription Factor', 'GATA6 Transcription Factor', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Mice', 'Molecular Sequence Data', 'Promoter Regions, Ge... | 18,832,096 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251'], ['A16.254'], ['D12.776.260.257', 'D12.776.930.314'], ['D12.776.260.257.400', 'D12.776.930.314.400'], ['D12.776.260.257.600', 'D12.776.930.314.600'], ['G05.308.310'], ['G05.308.320'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hodgkin lymphoma in a renal transplant recipient associated with low peripheral blood Epstein-Barr virus genome copies. | Posttransplant lymphoproliferative disorders are often accompanied by >500 Epstein-Barr virus (EBV) genome copies/10(5) lymphocytes, and they occur shortly after transplantation. Hodgkin lymphoma occurs rarely after transplantation, appearing a mean of 4.2 years posttransplant, and although Hodgkin lymphoma has strong ... | ['Adolescent', 'Antibodies, Viral', 'Biopsy', 'Bone Marrow', 'Herpesvirus 4, Human', 'Hodgkin Disease', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Kidney Transplantation', 'Lymph Nodes', 'Lymphocytes', 'Male', 'Polymerase Chain Reaction', 'RNA, Viral', 'Reed-Sternberg Cells'] | 11,698,007 | [['M01.060.057'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A15.382.216'], ['B04.280.210.400.500.450', 'B04.280.382.400.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence of muscle relaxant sensitivity in a general population: implications for a preoperative screening. | BACKGROUND: Muscle relaxants (MR) are responsible for 59% of peroperative anaphylactic reactions. A major issue would be to determine whether a systematic preoperative screening in the general population should be recommended.OBJECTIVE: The purpose of the study was to evaluate the prevalence of muscle relaxant sensitiv... | ['Adult', 'Female', 'France', 'Humans', 'Hypersensitivity, Immediate', 'Male', 'Muscle Relaxants, Central', 'Pancuronium', 'Preoperative Care', 'Prevalence', 'Skin Tests', 'Succinylcholine', 'Surveys and Questionnaires', 'Tetraethylammonium Compounds', 'Vecuronium Bromide'] | 10,051,704 | [['M01.060.116'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['D27.505.696.510', 'D27.505.696.663.700.600', 'D27.505.954.427.525'], ['D04.210.500.054.040.685'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Assignment of disulfide bond location in prothoracicotropic hormone of the silkworm, Bombyx mori: a homodimeric peptide. | The disulfide bond location of a homodimeric peptide, prothoracicotropic hormone (PTTH) of the silkworm, Bombyx mori, was determined by a combination of partial reduction and sequence analysis of peptide fragments generated through a partial reduction of PTTH followed by alkylation and enzyme digestion. The partial red... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Bombyx', 'Disulfides', 'Escherichia coli', 'Insect Hormones', 'Molecular Sequence Data', 'Peptide Mapping', 'Recombinant Proteins'] | 8,180,220 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D06.472.445.573'], ['L01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vibrio cholerae non-O1 septicaemia in a patient with liver cirrhosis and Billroth-II-gastrectomy. | This report deals with the first diagnosed case of Vibrio cholerae non-O1 septicaemia in Austria. After a vacation in Tunisia, a 51-year-old male patient with liver cirrhosis and Billroth-II-gastrectomy was admitted to hospital because of abdominal pain, growing ascites, and jaundice. Four days later, the patient devel... | ['Abdominal Pain', 'Ascites', 'Bacteremia', 'Fever', 'Gastrectomy', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Vibrio Infections', 'Vibrio cholerae'] | 9,120,332 | [['C23.888.592.612.054', 'C23.888.821.030'], ['C23.550.081'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['C23.888.119.344'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['C01.150.252.400.959'], ['B03.440.450.900.859.225'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Risk factors in chronic noncommunicable diseases]. | As a result of an epidemiological survey of able-bodied population aged 20-64, serviced by the territorial polyclinic of Minsk with the help of standard methods and standardized procedures, the data on the prevalence of some chronic non-communicable diseases and their risk factors were obtained. The high incidence of i... | ['Adult', 'Age Factors', 'Body Weight', 'Cholesterol', 'Chronic Disease', 'Coronary Disease', 'Exercise', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Republic of Belarus', 'Risk Factors', 'Smoking'] | 2,142,542 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C23.550.291.500'], ['C14.280.647.250', 'C14.907.585.250'], ['G11.427... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Inhibition of cell expansion by rapid ABP1-mediated auxin effect on microtubules. | The prominent and evolutionarily ancient role of the plant hormone auxin is the regulation of cell expansion. Cell expansion requires ordered arrangement of the cytoskeleton but molecular mechanisms underlying its regulation by signalling molecules including auxin are unknown. Here we show in the model plant Arabidopsi... | ['Arabidopsis', 'Arabidopsis Proteins', 'Cell Proliferation', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Hypocotyl', 'Indoleacetic Acids', 'Microtubules', 'Plant Proteins', 'Plant Roots', 'Receptors, Cell Surface', 'Signal Transduction'] | 25,409,144 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.393.332'], ['G05.308.375'], ['A18.024.875.750', 'A18.024.937.249', 'A18.550.500'], ['D03.066.288', 'D03.633.100.473.404'], ['A11.284.430.214.190.750.602'], ['D12.776.765'], ['A18.400'], ['D12.776.543.750'], ['G0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphometric investigations on bone giant cell tumors. | The authors have studied 12 cases of bone giant cell tumors and have shown that the increase in aggressiveness is accompanied by higher values of mitotic activity and nuclear features (area, perimeter, long and short axes), which might be useful for grading the bone giant cell tumors. | ['Bone Neoplasms', 'Cell Nucleus', 'Giant Cell Tumors', 'Humans', 'Stromal Cells'] | 9,577,682 | [['C04.588.149', 'C05.116.231'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C04.557.450.565.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Skin and needle hygiene intervention for injection drug users: results from a randomized, controlled Stage I pilot trial. | A new skin and needle hygiene intervention, designed to reduce high-risk injection practices associated with bacterial and viral infections, was tested in a pilot, randomized controlled trial. Participants included 48 active heroin injectors recruited through street outreach and randomized to either a 2-session interve... | ['Adult', 'Bacterial Infections', 'Feasibility Studies', 'Female', 'Follow-Up Studies', 'Health Behavior', 'Humans', 'Hygiene', 'Male', 'Middle Aged', 'Needles', 'Pilot Projects', 'Risk Reduction Behavior', 'Risk-Taking', 'Skin Care', 'Substance Abuse, Intravenous', 'Virus Diseases'] | 22,341,554 | [['M01.060.116'], ['C01.150.252'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547', 'N06.850.670'], ['M01.060.116.630'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Holding on to what you have got: keeping hospice palliative care volunteers volunteering. | In all, 119 hospice palliative care volunteers from 3 community-based hospice programs completed the Volunteer Retention Questionnaire (VRQ), a 33-item survey designed for this study. The VRQ asks volunteers to rate the importance of each item to their decision to continue volunteering. The items that received the high... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Hospices', 'Humans', 'Male', 'Middle Aged', 'Palliative Care', 'Personal Satisfaction', 'Personnel Management', 'Personnel Turnover', 'Surveys and Questionnaires', 'Volunteers', 'Workforce'] | 22,811,213 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N02.278.421.556.185', 'N02.421.143.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.666', 'N02.421.585.666'], ['F01.145.677'], ['N04.452.677'], ['N04.452.677.680'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of hyaluronan in mesothelium-induced motility of ovarian carcinoma cells. | BACKGROUND: Ovarian carcinoma metastases occur when the malignant cells establish new colonies on the peritoneal surface. This study was undertaken to determine whether mesothelial cell hyaluronan affects tumor cell motility.MATERIALS AND METHODS: Four ovarian carcinoma cell lines (UCI 101, UCI 107, OC 222 and NIH:OVCA... | ['Cell Adhesion', 'Cell Line, Tumor', 'Cell Movement', 'Chemotaxis', 'Coculture Techniques', 'Epithelial Cells', 'Female', 'Humans', 'Hyaluronic Acid', 'Hyaluronoglucosaminidase', 'Ovarian Neoplasms'] | 14,666,707 | [['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['E05.481.500.374'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['D08.811.277... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Signaled drug delivery and transport across the blood-brain barrier. | We use a mathematical model to describe the delivery of a drug to a specific region of the brain. The drug is carried by liposomes that can release their cargo by application of focused ultrasound (US). Thereupon, the drug is absorbed through the endothelial cells that line the brain capillaries and form the physiologi... | ['Blood-Brain Barrier', 'Doxorubicin', 'Drug Delivery Systems', 'Endothelial Cells', 'Humans', 'Levodopa', 'Models, Molecular'] | 26,572,864 | [['A07.035', 'A08.186.211.035'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319.300'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D12.125.072.050.685.400.500', 'D12.125.07... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An Easy-to-Use and Fast Assessment of Patient-Specific DBS-Induced Changes in Hand Motor Control in Parkinson's Disease. | For Parkinson's disease (PD), efficient and fast monitoring of fine motor function is fundamental for capturing transient phenomena induced by deep brain stimulation (DBS), thus, enabling a fast and accurate tuning of stimulation parameters. Tuning of DBS parameters is important for obtaining a patient-specific optimal... | ['Adult', 'Algorithms', 'Antiparkinson Agents', 'Deep Brain Stimulation', 'Dopamine Agonists', 'Female', 'Hand', 'Humans', 'Linear Models', 'Machine Learning', 'Male', 'Middle Aged', 'Parkinson Disease', 'Psychomotor Performance', 'Subthalamic Nucleus'] | 31,536,010 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['D27.505.954.427.090.050'], ['E02.331.300', 'E04.190'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Gonadal steroids, gonadotropins and endometrial histology in postmenopausal women with malignant ovarian tumors. | The concentrations of FSH, LH, 17-beta-estradiol (E2), estrone (E1) and progesterone (P) were measured in peripheral and ovarian vein sera obtained at preoperative pelvic angiography from 5 postmenopausal women with malignant ovarian tumors. In 5 others the concentrations of E2, P and testosterone (T) were also measure... | ['Adult', 'Endometrium', 'Estradiol', 'Estrone', 'Female', 'Follicle Stimulating Hormone', 'Gonadal Steroid Hormones', 'Gonadotropins, Pituitary', 'Humans', 'Luteinizing Hormone', 'Menopause', 'Middle Aged', 'Ovarian Neoplasms', 'Progesterone', 'Testosterone'] | 3,090,850 | [['M01.060.116'], ['A05.360.319.679.490'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.040.502.497', 'D06.472.334.851.437.996'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.334.851'], ['D... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Healing of human intrabony defects following regenerative periodontal therapy with an enamel matrix protein derivative alone or combined with a bioactive glass. A controlled clinical study. | AIM: The purpose of the present study was to compare clinically the treatment of deep intrabony defects with a combination of an enamel matrix protein derivative (EMD) and a bioactive glass (BG) to EMD alone.METHODS: Thirty patients (16 females and 14 males) suffering from advanced marginal periodontitis were included ... | ['Biocompatible Materials', 'Ceramics', 'Dental Enamel Proteins', 'Drug Therapy, Combination', 'Female', 'Humans', 'Male', 'Periodontal Attachment Loss', 'Periodontal Diseases', 'Prospective Studies', 'Wound Healing'] | 15,642,068 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['J01.637.153'], ['D12.776.231'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.714.354.750'], ['C07.465.714'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['G16.762.891']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effect of 7-nitro indazole on quinolinic acid-induced striatal toxicity in the rat. | Nitric oxide (NO) is implicated as a mediator of cell death in models of neurodegenerative disease. However, the precise role of NO in neuronal degeneration remains controversial. In the present study we employed 7-nitro indazole (7-NI), reportedly a selective inhibitor of neuronal nitric oxide synthase (nNOS) in vivo,... | ['Acetylcholinesterase', 'Animals', 'Corpus Striatum', 'Enzyme Inhibitors', 'Indazoles', 'Male', 'Microinjections', 'NADP', 'Neurons', 'Nitric Oxide Synthase', 'Quinolinic Acid', 'Rats', 'Rats, Wistar'] | 8,541,483 | [['D08.811.277.352.100.170.176'], ['B01.050'], ['A08.186.211.200.885.287.249.487'], ['D27.505.519.389'], ['D03.383.129.539.487', 'D03.633.100.449'], ['E02.319.267.530.690', 'E05.591.570'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['A08.675', 'A11.671'], ['D08.811.682... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets. | K-homology (KH) splicing regulator protein (KSRP) is a multi-domain RNA-binding protein that regulates different steps of mRNA metabolism, from mRNA splicing to mRNA decay, interacting with a broad range of RNA sequences. To understand how KSRP recognizes its different RNA targets it is necessary to define the general ... | ['Base Sequence', 'Binding Sites', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Binding', 'Protein Structure, Tertiary', 'RNA', 'RNA-Binding Proteins'] | 18,684,992 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.196.867.519.550'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.610'], ['D13.444.735'], ['D12.776.157.725', 'D12.776.664.962']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Education and home based training for intermittent claudication: functional effects and quality of life. | BACKGROUND: Supervised exercise programs increase physical performance in patients with peripheral artery disease (PAD). However, there are a limited number of programs, and to date they have failed to provide evidence of long-term adherence to exercise or any meaningful effect on Quality of Life (QoL). We created a pr... | ['Aged', 'Ankle Brachial Index', 'Exercise Test', 'Exercise Therapy', 'Female', 'France', 'Health Knowledge, Attitudes, Practice', 'Home Care Services', 'Humans', 'Intermittent Claudication', 'Male', 'Middle Aged', 'Patient Compliance', 'Patient Education as Topic', 'Patient Satisfaction', 'Peripheral Arterial Disease'... | 24,177,266 | [['M01.060.116.100'], ['E01.370.370.140.049'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['Z01.542.286'], ['F01.100.150.500', 'N05.300.150.410'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Evidence for interleukin-1 beta being a necessary but not sufficient co-stimulatory signal in monocyte-dependent anti-CD3-mediated T-cell triggering. | T-cell activation by CD3-specific antibodies is either monocyte independent or monocyte mediated, depending on the fine specificity and mode of presentation of anti-CD3. Monocyte-independent activation occurs when T cells encounter surface-bound antibody at high density, thereby mediating interleukin-2 (IL-2) productio... | ['Humans', 'Interleukin-1', 'Interleukin-6', 'Monocytes', 'Muromonab-CD3', 'Receptors, Interleukin-1', 'T-Lymphocytes'] | 8,300,152 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['A11.118.637.555.652', 'A11.148.58... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Treatment of patients with fractures of the odontoid of the C2 vertebra]. | The study was undertaken to improve an approach to treating patients with fractures of the odontoid of the C2 vertebra. Forty-nine patients were admitted to hospital for fractures of the odontoid process on January 14, 1989 to January 3, 2004. Physical, target X-ray study of the cervical spine, computed tomography of t... | ['Adolescent', 'Adult', 'Female', 'Fracture Fixation', 'Humans', 'Joint Dislocations', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neurosurgical Procedures', 'Odontoid Process', 'Spinal Fractures', 'Treatment Outcome'] | 15,912,867 | [['M01.060.057'], ['M01.060.116'], ['E04.555.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E04.525'], ['A02.835.232.834.151.383.668'], ['C26.117.500.500', 'C26.404.812'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changing impact of gastroesophageal reflux in medical and otolaryngology practice. | OBJECTIVES/HYPOTHESIS: A major trend in gastroesophageal reflux disease (GERD) is an observed increased prevalence of the problem, with an associated burden on health care resources. There are relatively few objective reports of increasing prevalence of this disease, and there are no epidemiologic reports that discuss ... | ['Adolescent', 'Adult', 'Ambulatory Care', 'Asthma', 'Counseling', 'Feeding Behavior', 'Female', 'Gastroesophageal Reflux', 'Gastrointestinal Diseases', 'Humans', 'Laryngitis', 'Male', 'Middle Aged', 'Office Visits', 'Otolaryngology', "Practice Patterns, Physicians'", 'Prevalence', 'Retrospective Studies', 'Tobacco Use... | 15,995,499 | [['M01.060.057'], ['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['C06.405.117.119.500.484'], ['C06.405'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
99mTc-MAG3 versus 131I-orthoiodohippurate in the routine determination of effective renal plasma flow. | 99mTc-mercaptoacetyltriglycine (MAG3) has been proposed as an alternative to 131I-orthoiodohippurate (OIH) for the scintigraphic determination of effective renal plasma flow (ERPF). The purpose of this study was to compare the ERPF values determined simultaneously with MAG3 and OIH by a dual channel technique in a larg... | ['Adult', 'Aged', 'Female', 'Humans', 'Iodine Radioisotopes', 'Iodohippuric Acid', 'Kidney', 'Male', 'Middle Aged', 'Oligopeptides', 'Organotechnetium Compounds', 'Radionuclide Imaging', 'Renal Circulation', 'Technetium Tc 99m Mertiatide'] | 2,147,211 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D02.065.277.431.579', 'D02.241.223.100.100.400.500', 'D02.241.755.360.579', 'D02.455.426.559.389.127.085.460.500'], ['A05.810.453'], ['M01.060.116.630'], ['D12.644... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of placebo tailoring on smoking cessation: a randomized controlled trial. | OBJECTIVE: Previous research has found that smoking cessation messages can be designed to appear as tailored (placebo tailored) and result in superior outcomes compared to standard messages. In the current study, we aimed (a) to test the efficacy of placebo tailoring for smoking cessation and (b) to examine the influen... | ['Adult', 'Cognition', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Pamphlets', 'Patient Education as Topic', 'Personality', 'Placebos', 'Secondary Prevention', 'Smoking', 'Smoking Cessation', 'Treatment Outcome'] | 23,544,680 | [['M01.060.116'], ['F02.463.188'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['L01.178.682.707'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F01.752'], ['D26.660'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Changing pattern of intestinal obstruction in Accra, Ghana. | BACKGROUND/AIMS: Over the past 50 years acute intestinal obstruction has remained among the commonest causes of the acute abdomen, along with peritonitis, appendicitis and gastrointestinal perforations. However several observers have noticed over the past 2 decades a shift in the etiological spectrum. The study aims at... | ['Acute Disease', 'Female', 'Ghana', 'Humans', 'Incidence', 'Intestinal Obstruction', 'Male', 'Risk Factors', 'Socioeconomic Factors'] | 10,690,607 | [['C23.550.291.125'], ['Z01.058.290.190.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C06.405.469.531'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.85... | ['Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Some aspects of the genetic toxicity of methylmercury in yeasts]. | Methylmercury chloride is a powerful inhibitor of the cell cycle in Yeasts. Its effect is reversible at low doses. It does not induce any nuclear mutation (at least among the ones we tested). Neither does it increase the amounts of intra and inter-genic conversions induced by a variety of mutagenic agents. However, in ... | ['Ascomycota', 'Cell Cycle', 'Methylmercury Compounds', 'Mutation', 'Saccharomyces cerevisiae', 'Schizosaccharomyces', 'Species Specificity'] | 6,820,301 | [['B01.300.107'], ['G04.144'], ['D02.691.750.100.738'], ['G05.365.590'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['B01.300.107.797', 'B01.300.930.720'], ['G16.824']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel use of acellular dermal matrix in the formation of a bioprosthetic silo for giant omphalocele coverage. | A case report is presented on the utilization of an acellular dermal matrix in the formation of a biologic silo conducive to early epithelial grafting in the treatment of a giant omphalocele associated with cloacal exstrophy. | ['Bioprosthesis', 'Cells, Cultured', 'Cloaca', 'Extracellular Matrix', 'Hernia, Umbilical', 'Humans', 'Infant, Newborn', 'Keratinocytes', 'Male', 'Meningomyelocele', 'Skin Transplantation', 'Surgical Mesh', 'Tissue Engineering', 'Urinary Bladder Diseases'] | 15,300,551 | [['E07.695.100'], ['A11.251'], ['A13.223', 'A16.178'], ['A11.284.295.310'], ['C16.614.378', 'C23.300.707.374.937.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A11.409.500', 'A11.436.397'], ['C10.500.680.610', 'C16.131.666.680.610'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.58... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Incidence of workers compensation indemnity claims across socio-demographic and job characteristics. | BACKGROUND: We hypothesized that low socioeconomic status, employer-provided health insurance, low wages, and overtime were predictors of reporting workers compensation indemnity claims. We also tested for gender and race disparities.METHODS: Responses from 17,190 (person-years) Americans participating in the Panel Stu... | ['Accidents, Occupational', 'Adult', 'African Americans', 'Demography', 'Educational Status', 'Female', 'Health Benefit Plans, Employee', 'Hispanic Americans', 'Humans', 'Logistic Models', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Odds Ratio', 'Salaries and Fringe Benefits', 'Sex Factors', 'United States', "Worke... | 21,761,427 | [['N06.850.135.240'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['N01.824.196'], ['N01.824.417.700.325', 'N03.219.521.576.343.290', 'N04.452.677.800.325'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318... | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Comparison of the anti-inflammatory properties of formoterol, salbutamol and salmeterol in guinea-pig skin and lung. | 1. We have compared some anti-inflammatory properties of formoterol, salbutamol and salmeterol in guinea-pig skin and lung. 2. Intradermal formoterol (1 x 10(-10) to 1 x 10(-8) mol/site), salbutamol (1 x 10(-8) and 1 x 10(-7) mol/site) and salmeterol (1 x 10(-8) and 1 x 10(-7) mol/site) inhibited bradykinin-induced pla... | ['Adrenergic beta-Agonists', 'Albuterol', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Blood Proteins', 'Bronchoalveolar Lavage Fluid', 'Ethanolamines', 'Formoterol Fumarate', 'Granulocytes', 'Guinea Pigs', 'Histamine', 'Humans', 'In Vitro Techniques', 'Infant, Newborn', 'Lung', 'Male', 'Neutrophils', 'Platel... | 7,902,175 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D12.776.124'], ['E05.927.100.500'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.06... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Once-monthly oral ibandronate compared with weekly oral alendronate in postmenopausal osteoporosis: results from the head-to-head MOTION study. | OBJECTIVE: Oral ibandronate 150 mg is the first bisphosphonate approved for once-monthly treatment of postmenopausal osteoporosis. To investigate whether once-monthly ibandronate 150 mg increases lumbar spine and total hip bone mineral density (BMD) to the same degree as weekly alendronate 70 mg.RESEARCH DESIGN AND MET... | ['Administration, Oral', 'Aged', 'Aged, 80 and over', 'Alendronate', 'Algorithms', 'Bone Density', 'Bone Density Conservation Agents', 'Diphosphonates', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Humans', 'Ibandronic Acid', 'Middle Aged', 'Osteoporosis, Postmenopausal', 'Treatment Outcome'] | 18,042,311 | [['E02.319.267.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.705.429.500.100'], ['G17.035', 'L01.224.050'], ['G11.427.100'], ['D27.505.696.242'], ['D02.705.429.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Prediction for sustained deep molecular response of BCR-ABL1 levels in patients with chronic myeloid leukemia in chronic phase. | BACKGROUND: The achievement of a sustained deep molecular response is a goal of increasing relevance because it opens the possibility of treatment discontinuation. The objective of this analysis was to develop a prediction model for a sustained molecular response with BCR-ABL1 level <0.0032% on the international scale ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Female', 'Follow-Up Studies', 'Fusion Proteins, bcr-abl', 'Humans', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Middle Aged', 'Models, Biological', 'Prognosis', 'Prospective Studies', 'Protein Kinase Inhibitors', 'Randomized... | 29,266,206 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D08.811.913.696.620.682.725.500.500', 'D12.776.602.500.500.100', 'D12.776.624.664.500.100', 'D12.776.624.664.700.171.500'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is normal pregnancy atherogenic? | Serum cholesterol, triacylglycerols and low-density lipoprotein (LDL) subfractions were determined in 120 primagravid women during normal gestation (40 in each trimester) and in 20 non-pregnant age-matched controls. LDL subfractions were determined by PAGE, and an LDL score was calculated. The higher the score, the sma... | ['Adult', 'Arteriosclerosis', 'Case-Control Studies', 'Cholesterol', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Humans', 'Lipoproteins, LDL', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnancy Trimester, Second', 'Pregnancy Trimester, Third', 'Triglycerides'] | 10,087,251 | [['M01.060.116'], ['C14.907.137.126'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.515', 'D12.776.521.550'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High FDG activity in focal fat necrosis: a pitfall in interpretation of posttreatment PET/CT in patients with non-Hodgkin lymphoma. | PURPOSE: PET/CT has a major role in lymphoma imaging, but glycolytic activity in inflammatory processes can reduce specificity. In this study we evaluated restaging PET/CT findings in patients with non-Hodgkin lymphoma (NHL) and fat necrosis.METHODS: We identified 16 patients from 8,819 restaging FDG PET/CT scans with ... | ['Adult', 'Aged', 'False Positive Reactions', 'Fat Necrosis', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Positron-Emission Tomography', 'Radiopharmaceuticals', 'Tomography, X-Ray Computed'] | 23,653,244 | [['M01.060.116'], ['M01.060.116.100'], ['E01.354.506'], ['C23.550.717.365'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['E01.370.350.567'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Poverty, social exclusion and health in Portugal. | People in Portugal have never been so healthy. Nevertheless, there are great differences in health status between social groups and regions. In 1994, Portugal was the country with the second worst level of inequality in terms of income distribution and with the highest level of poverty in the European Union (EU). Pover... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Cultural Deprivation', 'European Union', 'Family Characteristics', 'Female', 'Health Services', 'Health Services Accessibility', 'Health Status Indicators', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Portugal', 'Poverty', 'Social Isolation', 'Social Securit... | 12,137,187 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['I01.880.853.100.400'], ['I01.615.500.475'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['N02.421'], ['N04.590.374.350', 'N05.300.430'], ['E05.318.308.980.4... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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