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Phosphorus-31 NMR spectroscopy of cultured human retinal pigmented epithelial cells. | Cultured human retinal pigmented epithelial cells were studied using phosphorus-31 nuclear magnetic resonance spectroscopy (P-31 NMR). Retinal pigmented epithelial cells from normal human donors were isolated and expanded using roller-bottle culture. The P-31 NMR spectrum of the intact living cells was obtained at 121 ... | ['Cells, Cultured', 'Humans', 'Magnetic Resonance Spectroscopy', 'Phosphorus', 'Pigment Epithelium of Eye'] | 3,804,654 | [['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['D01.268.666'], ['A09.371.670', 'A10.272.640']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The clinical and genetic characteristics of spinocerebellar ataxia type 7 (SCA 7) in three Black South African families. | OBJECTIVES: Spinocerebellar ataxia type 7 is a rare autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and retinal degeneration, described in various population groups in the literature. This is the first description from South Africa. The objective was to document the clinical and ge... | ['Adult', 'African Continental Ancestry Group', 'Aged', 'Atrophy', 'Brain Stem', 'Cerebellum', 'Child', 'DNA Mutational Analysis', 'DNA Primers', 'Female', 'Fundus Oculi', 'Genomic Imprinting', 'Humans', 'Macular Degeneration', 'Male', 'Pedigree', 'Point Mutation', 'Polymerase Chain Reaction', 'South Africa', 'Spinocer... | 10,705,940 | [['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['C23.300.070'], ['A08.186.211.132'], ['A08.186.211.132.810.428.200'], ['M01.060.406'], ['E05.393.760.700.300'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A09.371.729.313'], ['G05.308.203.500'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Osseous manifestations of elbow stress associated with sports activities. | The radiographic manifestations of musculoskeletal stress at the elbow associated with racket and throwing sports are reported in 29 symptomatic amateur, juvenile, and professional athletes. Five major categories of stress are identified: diffuse, humeral shaft, medial tension, lateral compression, and extension stress... | ['Adolescent', 'Adult', 'Aged', 'Athletic Injuries', 'Baseball', 'Cartilage, Articular', 'Child', 'Elbow Joint', 'Female', 'Humans', 'Humeral Fractures', 'Humerus', 'Male', 'Middle Aged', 'Radiography', 'Tennis', 'Ulna', 'Ulna Fractures'] | 6,768,275 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C26.115'], ['I03.450.642.845.110'], ['A02.165.407.150', 'A02.835.583.192'], ['M01.060.406'], ['A02.835.583.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.088.390', 'C26.404.500'], ['A02.835.232.087.090.400'], ['M01.060.116.630'], ['E01.370.350.700... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
A modified monobloc for the treatment of obstructive sleep apnoea in paediatric patients. | The aims of this study were to determine the differences in craniofacial morphology between children with obstructive sleep apnoea (OSA) and control subjects, and to investigate the effects of modified monobloc (MM) appliance treatment in OSA children. The treatment group consisted of 20 OSA Caucasian subjects (10 boys... | ['Cephalometry', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Orthodontic Appliance Design', 'Orthodontic Appliances', 'Sleep Apnea, Obstructive', 'Statistics, Nonparametric'] | 15,536,841 | [['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.320.274', 'E06.658.450', 'E06.912.675'], ['E06.658.453'], ['C08.618.085.852.850', 'C10.886.425.800.750.850'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of a nitric oxide releasing derivative of paracetamol in a rat model of endotoxaemia. | BACKGROUND AND PURPOSE: Nitroparacetamol is a nitric oxide-releasing paracetamol with novel anti-inflammatory properties compared to the parent compound. This study has investigated the anti-inflammatory activity of nitroparacetamol in a model of endotoxaemia in rats to probe the mechanisms underlying this effect.EXPER... | ['Acetaminophen', 'Acetylcholine', 'Animals', 'Aspartate Aminotransferases', 'Blood Pressure', 'Creatinine', 'Cyclooxygenase 2', 'Disease Models, Animal', 'Endotoxemia', 'Heart Rate', 'Kidney', 'Lipopolysaccharides', 'Liver', 'Lung', 'Male', 'Nitrates', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'Nitrites', 'Nitr... | 16,940,991 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D02.092.211.111'], ['B01.050'], ['D08.811.913.477.700.225'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.383.129.308.207'], ['D08.811.600.720.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C01.757.100.275', 'C01.861.375', 'C23.550.470.790.500.100.275... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Geometric symmetry of the solar surface of hooves of thoroughbred racehorses. | OBJECTIVE: To define a 3-dimensional (3-D) coordinate system with clear definitions of origins and axes relative to hoof anatomic features and determine whether solar surfaces of Thoroughbred racehorse hooves have geometric asymmetry in the mediolateral and dorsopalmar directions.SAMPLE POPULATION: Left forelimb hooves... | ['Animals', 'Female', 'Forelimb', 'Hoof and Claw', 'Horses', 'Male', 'Physical Conditioning, Animal'] | 12,926,598 | [['B01.050'], ['A13.395'], ['A13.491'], ['B01.050.150.900.649.313.984.235.472'], ['G11.427.410.698.277.280']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Natural killer cell activity in Naegleria fowleri infected mice]. | The natural killer (NK) cell activity of splenocytes and recycling capacity of NK cells were observed by combining the 51Cr-release cytotoxicity assay and single cell cytotoxicity assay against YAC-1. The ICR mice were infected intranasally with Naegleria fowleri, that is a pathogenic free-living amoeba. The mice infec... | ['Amebiasis', 'Animals', 'Cytotoxicity, Immunologic', 'Killer Cells, Natural', 'Mice', 'Mice, Inbred ICR', 'Naegleria fowleri'] | 1,786,253 | [['C01.610.752.049'], ['B01.050'], ['G12.287'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['B01.046.500.700.710.375']] | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary copper deficiency and autoimmunity in the NZB mouse. | NZB mice were exposed from birth to a diet either adequate or deficient in copper. By age 6 wk the mice exposed to the copper-deficient diet showed symptoms characteristic of copper deficiency (anemia, hypoceruloplasminemia, and achromatrichia). The splenic lymphocytes from the copper-deficient group had reduced number... | ['Animals', 'Antibodies, Antinuclear', 'Antibody Specificity', 'Antigens, Surface', 'Autoantibodies', 'Ceruloplasmin', 'Colony-Forming Units Assay', 'Copper', 'DNA, Single-Stranded', 'Female', 'Hemolytic Plaque Technique', 'Lymphocytes', 'Mice', 'Mice, Inbred NZB', 'Organ Size', 'Spleen', 'Thymus Gland'] | 3,318,378 | [['B01.050'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['G12.100'], ['D23.050.301'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short-term adaptation of saccades does not affect smooth pursuit eye movement initiation. | Scrutiny of the visual environment requires saccades that shift gaze to objects of interest. In case the object should be moving, smooth pursuit eye movements (SPEM) try to keep the image of the object within the confines of the fovea in order to ensure sufficient time for its analysis. Both saccades and SPEM can be ad... | ['Adaptation, Physiological', 'Animals', 'Fixation, Ocular', 'Macaca mulatta', 'Male', 'Models, Animal', 'Probability', 'Pursuit, Smooth', 'Saccades'] | 28,837,965 | [['G07.025', 'G16.012.500'], ['B01.050'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['E05.598'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['G14.350.453'], ['G14.350.500']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
SCAR and CAPS mapping of CRb, a gene conferring resistance to Plasmodiophora brassicae in Chinese cabbage ( Brassica rapa ssp. pekinensis). | Clubroot disease, caused by Plasmodiophora brassicae Wor., is highly damaging for Chinese cabbage. The CR (clubroot resistant) Shinki DH (doubled haploid) line of Chinese cabbage carries a single dominant gene, CRb, which confers resistance to the P. brassicae races 2, 4, and 8. An F(2) population derived from a cross ... | ['Brassica', 'Chromosome Mapping', 'Chromosome Segregation', 'Chromosomes, Plant', 'Eukaryotic Cells', 'Fungi', 'Genes, Plant', 'Genetic Markers', 'Plant Diseases', 'Polymerase Chain Reaction'] | 14,997,298 | [['B01.650.940.800.575.912.250.157.200'], ['E05.393.183'], ['G04.144.220.220.625', 'G05.113.220.625'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['A11.450'], ['B01.300'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D23.101.387', 'G05.695.450'], ['G15.610'], ['E05.393.620.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinicopathological significance of ERCC1 expression in breast cancer. | The excision repair cross-complementation 1 (ERCC1) enzyme plays an essential role in the nucleotide excision repair pathway and is associated with resistance to platinum-based chemotherapy in different types of cancer. The aim of the present study was to evaluate the clinicopathological significance of ERCC1 expressio... | ['Adult', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Carcinoma', 'Chi-Square Distribution', 'DNA-Binding Proteins', 'Endonucleases', 'Female', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Middle Aged', 'Neoplasm Staging', 'Predictive Value of Tests', 'Prognosis', 'Risk Factors', 'Time Factors', 'Tissue Ar... | 23,702,380 | [['M01.060.116'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D12.776.260'], ['D08.811.277.352.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.75... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Reperfusion reduces left ventricular dilatation by preventing infarct expansion in the acute and chronic phases of myocardial infarction. | Reperfusion reduces left ventricular dilatation in patients with acute myocardial infarction, but it is unclear to what extent this is a primary effect or only a consequence of the limiting effect of reperfusion on infarct size. To address this issue, 56 consecutive patients were examined by means of two-dimensional ec... | ['Adult', 'Coronary Angiography', 'Creatine Kinase', 'Dilatation, Pathologic', 'Echocardiography', 'Heart Ventricles', 'Humans', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Reperfusion', 'Systole', 'Time Factors'] | 8,122,595 | [['M01.060.116'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['D08.811.913.696.640.150'], ['C23.300.325'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primary rhegmatogenous retinal detachment: risk factors for macular involvement. | PURPOSE: Rhegmatogenous retinal detachment (RD) has diagnostically been divided into macula-OFF or macula-ON. The aim of this study was to describe the demographics and primary outcome of patients with RD following surgery with respect to the macular status, and to determine risk factors for macular involvement.METHODS... | ['Axial Length, Eye', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Macula Lutea', 'Male', 'Middle Aged', 'Prospective Studies', 'Retinal Detachment', 'Risk Assessment', 'Risk Factors', 'Switzerland', 'Tomography, Optical Coherence', 'Visual Acuity'] | 29,282,564 | [['A09.371.199', 'E01.370.600.115.100.660.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A09.371.729.522... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of caffeine on adenosine-induced reversible perfusion defects assessed by automated analysis. | OBJECTIVES: This prospective study investigated the effects of caffeine ingestion on the extent of adenosine-induced perfusion abnormalities during myocardial perfusion imaging (MPI).METHODS: Thirty patients with inducible perfusion abnormalities on standard (caffeineabstinent) adenosine MPI underwent repeat testing wi... | ['Adenosine', 'Blood Flow Velocity', 'Caffeine', 'Coronary Artery Disease', 'Coronary Circulation', 'Drug Interactions', 'Exercise Test', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Middle Aged', 'Myocardial Perfusion Imaging', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Va... | 22,302,182 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['E01.370.370.130', 'G09.330.380.630.080'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['G09.330.100.324'], ['G07.690.773.968'], ['E01.370.370.380.250', 'E01.370.386.700.25... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Conformational analysis of anti-arrhythmia agents of the lidocaine series and a model for the mechanism of their action]. | After conformation analysis of a number of lidocaine-like antiarrhythmic molecules a simple model of their mode of action is suggested. It is proposed that the hydrophobic antiarrhythmic molecules after their absorption on cytoplasmic membranes concentrate due to polar interactions close to ionic channel proteins, then... | ['Allosteric Regulation', 'Anti-Arrhythmia Agents', 'Cell Membrane', 'Ion Channels', 'Lidocaine', 'Membrane Proteins', 'Molecular Conformation', 'Structure-Activity Relationship'] | 2,470,414 | [['G02.111.044'], ['D27.505.954.411.097'], ['A11.284.149'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['D12.776.543'], ['G02.111.570.820'], ['G02.111.830', 'G07.690.773.997']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Double Selection Enhances the Efficiency of Target-AID and Cas9-Based Genome Editing in Yeast. | CRISPR-Cas9 loss of function (LOF) and base editing screens are powerful tools in genetics and genomics. Yeast is one of the main models in these fields, but has only recently started to adopt this new toolkit for high throughput experiments. We developed a double selection strategy based on co-selection that increases... | ['Algorithms', 'CRISPR-Cas Systems', 'Gene Editing', 'Gene Order', 'Gene Targeting', 'Genetic Loci', 'Genetic Vectors', 'Genome, Fungal', 'Genomics', 'Models, Genetic', 'Selection, Genetic', 'Yeasts'] | 30,097,473 | [['G17.035', 'L01.224.050'], ['G05.308.203.374.394'], ['E05.393.420.270'], ['G05.340'], ['E05.393.335'], ['G05.360.340.024.380'], ['G05.360.337'], ['G05.360.340.358.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.599.395.397'], ['G05.783'], ['B01.300.930']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The mechanism of parathyroid hormone action on calcium reabsorption by the distal tubule. | PTH increases calcium reabsorption exclusively in the distal nephron. Two mechanisms of Ca++ transport through the basolateral membrane (BLM) have been described: the ATP-dependent and the sodium gradient-dependent transport. In the present study, we investigated the effect of PTH and (Bu)2cAMP on these two mechanisms.... | ['Animals', 'Biological Transport, Active', 'Bucladesine', 'Calcium', 'Calcium-Transporting ATPases', 'Carrier Proteins', 'Cell Membrane', 'In Vitro Techniques', 'Kidney Cortex', 'Kidney Tubules, Distal', 'Kidney Tubules, Proximal', 'Kinetics', 'Parathyroid Hormone', 'Rabbits', 'Sodium-Calcium Exchanger', 'Tetradecanoy... | 1,846,100 | [['B01.050'], ['G03.143.310'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of awareness of the Japanese Food Guide Spinning Top on eating behaviour. | OBJECTIVE: To investigate whether awareness of the Japanese Food Guide (JFG) can promote changes in eating behaviour.DESIGN: A longitudinal study was conducted in 2007 and 2009 by means of an Internet-based survey. Awareness status of the JFG and a sixteen-item scale for calculating eating behaviour scores were obtaine... | ['Adult', 'Diet', 'Diet Surveys', 'Feeding Behavior', 'Female', 'Food Preferences', 'Guidelines as Topic', 'Health Behavior', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Internet', 'Japan', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Nutrition Policy', 'Nutritional Requirements', 'Young Adult'] | 21,859,513 | [['M01.060.116'], ['G07.203.650.240'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.407.516', 'G07.203.650.353.516'], ['N04.761.700.350', 'N05.700.350'], ['F01.145.488'], ['F01.100.150.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Paraplegia after contrast media application: a transient or devastating rare complication? Case report. | The authors report the case of a 76-year-old man with a spinal dural arteriovenous fistula. The patient suffered from sudden repeated reversible paraplegia after spinal digital subtraction angiography as well as CT angiography. Neurotoxicity of contrast media (CM) is the most probable cause for this repeated short-last... | ['Aged', 'Angiography, Digital Subtraction', 'Central Nervous System Vascular Malformations', 'Computed Tomography Angiography', 'Contrast Media', 'Humans', 'Male', 'Paraplegia', 'Spinal Cord Diseases'] | 26,544,597 | [['M01.060.116.100'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['C10.500.190', 'C14.240.850.875', 'C16.131.240.850.875', 'C16.131.666.190'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case of renal cell carcinoma in tuberous sclerosis followed by basic fetoprotein--a new carcinoembryonic protein]. | There have been very few reports on renal malignancies in tuberous sclerosis and only 9 cases have been reported in the Japanese literature. A second case of renal cell carcinoma in tuberous sclerosis in Japan is reported. The present case is a 29-year-old male who visited our clinic with the chief complaint of right f... | ['Adenocarcinoma', 'Adult', 'Fetal Proteins', 'Humans', 'Kidney Neoplasms', 'Male', 'Tuberous Sclerosis'] | 6,475,686 | [['C04.557.470.200.025'], ['M01.060.116'], ['D12.776.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.445.810', 'C04.651.800', 'C04.700.700', 'C10.500.507.400.750', 'C10.562.850', 'C10.574.500.865',... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of mastoid vibration with canalith repositioning procedure to treat persistent benign paroxysmal positional vertigo: A case report. | The Canalith Repositioning Procedure (CRP) was originally described as a non-invasive treatment for Benign Paroxysmal Positional Vertigo (BPPV) by Epley. Since its inception, the maneuver has undergone several modifications; and currently is performed in the absence of induced mastoid vibration (oscillation). Clinicall... | ['Benign Paroxysmal Positional Vertigo', 'Female', 'Humans', 'Mastoid', 'Middle Aged', 'Physical Therapy Modalities', 'Vibration'] | 29,336,656 | [['C09.218.568.900.883.500', 'C10.597.951.500', 'C23.888.592.958.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.885.444'], ['M01.060.116.630'], ['E02.779', 'E02.831.535'], ['G01.374.930']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Egg coats of the rock shrimp Rhynchocinetes typus: ultrastructural characterization and their function during fertilization. | The aim of the present work was to characterize structurally and ultrastructurally the egg coats of the rock shrimp, Rhynchocinetes typus, and to describe their functional roles during fertilization. Oocytes fixed directly from the ovary, have a total diameter of 549 microm and are covered by a 10- microm-thick transpa... | ['Animals', 'Cell Size', 'Decapoda', 'Female', 'Fertilization', 'Male', 'Ovum', 'Solubility', 'Sperm-Ovum Interactions', 'Spermatozoa'] | 12,410,613 | [['B01.050'], ['G04.325'], ['B01.050.500.131.365.190'], ['G08.686.784.277'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['G02.805'], ['G08.686.784.277.800'], ['A05.360.490.890', 'A11.497.760']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lipid composition of circulating multiple-modified low density lipoprotein. | Atherogenic modified low- density lipoprotein (LDL) induces pronounced accumulation of cholesterol and lipids in the arterial wall, while native LDL seems to lack such capability. Therefore, modified LDL appears to be a major causative agent in the pathogenesis of atherosclerosis. Possible modifications of LDL particle... | ['Adult', 'Case-Control Studies', 'Cholesterol', 'Cholesterol Esters', 'Coronary Artery Disease', 'Female', 'Humans', 'Lipoproteins, LDL', 'Lysophosphatidylcholines', 'Male', 'Middle Aged', 'Phosphatidylcholines', 'Phosphatidylethanolamines', 'Sphingomyelins'] | 27,558,696 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Treatment of neurological complication due to postgastrectomy vitamin E deficiency]. | Although postgastrectomy vitamin E deficiency rarely occurs, it can cause neuromuscular disorder such as neuropathy, myopathy and cerebellar ataxia. We encounter a lot of cases whose serum vitamin E level were decreased after gastrectomy. We evaluated the oral vitamin E intake as a therapy to these cases. The subjects ... | ['Administration, Oral', 'Aged', 'Aged, 80 and over', 'Female', 'Gastrectomy', 'Humans', 'Male', 'Middle Aged', 'Peripheral Nervous System Diseases', 'Postoperative Complications', 'Vitamin E', 'Vitamin E Deficiency'] | 15,856,761 | [['E02.319.267.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.668.829'], ['C23.550.767'], ['D03.383.663.283.909', 'D03.633.100.150.909'], ['C18.654.521.500.133.841']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adaptation of a reaching model to handwriting: how different effectors can produce the same written output, and other results. | This report shows how a model initially developed for the control of reaching can be adapted for the control of handwriting. The main problem addressed by the model is how people can produce essentially the same written output with different effectors (e.g., the preferred or nonpreferred hand, the foot, or even the mou... | ['Female', 'Functional Laterality', 'Handwriting', 'Humans', 'Kinesthesis', 'Male', 'Motor Skills', 'Orientation', 'Posture', 'Psychomotor Performance', 'Reaction Time'] | 8,693,052 | [['F02.830.297.425', 'G11.561.225.425'], ['L01.559.423.906.539'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['F02.808.260'], ['F01.058.577', 'F02.830.606'], ['G11.427.695'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rice dwarf viruses with dysfunctional genomes generated in plants are filtered out in vector insects: implications for the origin of the virus. | Rice dwarf virus (RDV), with 12 double-stranded RNA (dsRNA) genome segments (S1 to S12), replicates in and is transmitted by vector insects. The RDV-plant host-vector insect system allows us to examine the evolution, adaptation, and population genetics of a plant virus. We compared the effects of long-term maintenance ... | ['Animals', 'Cell Line', 'Codon, Nonsense', 'Disease Vectors', 'Insecta', 'Oryza', 'Plant Diseases', 'Reoviridae', 'Selection, Genetic', 'Viral Proteins'] | 21,191,024 | [['B01.050'], ['A11.251.210'], ['D13.444.735.544.355.250.235', 'G05.360.335.355.250.235', 'G05.365.590.195'], ['N06.850.335.188', 'N06.850.520.203.375'], ['B01.050.500.131.617'], ['B01.650.940.800.575.912.250.822.616'], ['G15.610'], ['B04.820.223.719'], ['G05.783'], ['D12.776.964']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Motion-induced sickness following bilateral ablation of area postrema in squirrel monkeys. | Using squirrel monkeys as experimental subjects, we reexamined the disputed role of the area postrema (AP) in motion-induced vomiting. After anesthetization, the obex and rhomboid fossa were exposed surgically, and the AP was ablated by thermal coagulation using either a battery cautery or a CO2 microsurgical laser. Sh... | ['Animals', 'Cerebral Ventricles', 'Chemoreceptor Cells', 'Male', 'Motion Sickness', 'Saimiri', 'Vomiting'] | 3,773,620 | [['B01.050'], ['A08.186.211.140'], ['A08.675.650.915.500', 'A08.800.950.500', 'A11.671.650.915.500'], ['C23.888.571'], ['B01.050.150.900.649.313.988.400.600.150.710.710'], ['C23.888.821.937']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[FLT3 internal tandem duplication in patients with acute promyelocytic leukemia]. | OBJECTIVE: To analyze the mutation of FLT3 internal tandem duplication (FLT3-ITD) in bone marrow cells from patients with newly-diagnosed acute promyelocytic leukemia (APL).METHODS: The mutation of FLT3-ITD in bone marrow mononuclear cells (MNCs) from 103 APL patients were screened by polymerase chain reaction (PCR) an... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Leukemia, Promyelocytic, Acute', 'Male', 'Middle Aged', 'Mutation', 'Tandem Repeat Sequences', 'fms-Like Tyrosine Kinase 3'] | 17,939,400 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275.700'], ['M01.060.116.630'], ['G05.365.590'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', 'G05.360.340.024.850'], ['D08.811.913.696.620.682.725.400.020', 'D12.776... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Clinical utilization of veiled incision and sternocleidomastoid flap in parotidectomy of parotid benign tumors]. | PURPOSE: To describe a modified technique of parotidectomy using face-lift approach and sternocleidomastoid flap.METHODS: Forty-six patients were divided into two groups; group 1 (23 cases) using veiled incision and sternocleidomastoid flap, group 2 (23 cases) using traditional incision (Blair's approach) without stern... | ['Ear Auricle', 'Face', 'Humans', 'Neoplasms', 'Parotid Gland', 'Parotid Neoplasms', 'Postoperative Complications', 'Surgical Flaps', 'Sweating, Gustatory'] | 20,635,029 | [['A09.246.272.197'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770', 'C07.465.815.718.589'], ['C23.550.767'], ['A10.850.710', 'E07.862.710'], ['C10.177.825... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fludarabine in combination with cyclophosphamide decreases incidence of GVHD and maintains effective graft-versus-leukemia effect after allogeneic stem cell transplantation in murine lymphocytic leukemia. | Graft-versus-host disease (GVHD) is a severe disorder and despite therapeutic efforts to decrease its distressing clinical manifestations, treatment is still not optimal. Here we report the results of studies, in which the purine analogue, fludarabine phosphate, was used in an attempt to modify and decrease GVHD after ... | ['Animals', 'Apoptosis', 'Crosses, Genetic', 'Cyclophosphamide', 'Drug Therapy, Combination', 'Graft vs Host Disease', 'Leukemia, B-Cell', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred Strains', 'Skin', 'Spleen', 'Stem Cell Transplantation', 'Transplantation, Homologous', 'Vidarabine'] | 12,621,501 | [['B01.050'], ['G04.146.954.035'], ['E05.393.281'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E02.319.310'], ['C20.452'], ['C04.557.337.428.080', 'C15.604.515.560.080', 'C20.683.515.528.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence. | BACKGROUND: Chemotherapeutic drugs like Adriamycin (ADR) induces apoptosis or senescence in cancer cells but these cells often develop resistance and generate responses of short duration or complete failure. The methylxantine drug Pentoxifylline (PTX) used routinely in the clinics setting for circulatory diseases has b... | ['Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis', 'Blotting, Western', 'Caspases', 'Cell Line, Tumor', 'Cell Separation', 'Cell Survival', 'Cellular Senescence', 'DNA Fragmentation', 'Doxorubicin', 'Enzyme Activation', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Flow Cytometry', 'Gene Expression', 'He... | 20,482,878 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.251.210.190', 'A11.251... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of probucol on elderly hypercholesterolemic patients in the FAST study. | The present study involved a detailed post hoc comparison of the efficacy and safety of lipid-lowering therapy in elderly hypercholesterolemic patients from the Fukuoka Atherosclerosis Trial (FAST). The FAST cohort of 246 hypercholesterolemic patients included 76 patients who were (75 years old. Patients were randomize... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Anticholesteremic Agents', 'Atherosclerosis', 'Cardiovascular Diseases', 'Carotid Arteries', 'Carotid Artery Diseases', 'Cohort Studies', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Hypercholesterolemia', 'Incidence', 'Male', 'Middle Aged... | 16,613,215 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['C14.907.137.126.307'], ['C14'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.5... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pudendal afferents mapping in posterior sacral rhizotomies. | BACKGROUND: The effectiveness of pudendal afferents mapping in posterior sacral rhizotomies needs to be reviewed.OBJECTIVE: To evaluate the effectiveness of pudendal afferents mapping for both the dorsal penile or clitoral nerve and the inferior anal nerve to decrease the risk of postoperative bowel and bladder dysfunc... | ['Action Potentials', 'Adolescent', 'Afferent Pathways', 'Asian Continental Ancestry Group', 'Cerebral Palsy', 'Child', 'Child, Preschool', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials', 'Female', 'Humans', 'Intestinal Diseases', 'Intraoperative Neurophysiological Monitoring', 'Male', 'Pudendal Nerve'... | 24,165,168 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.057'], ['A08.612.220'], ['M01.686.508.200'], ['C10.228.140.140.254'], ['M01.060.406'], ['M01.060.406.448'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Insulin-like growth factor-II expression in developing skeletal muscle of double muscled and normal cattle. | Double muscled (DM) cattle possess nearly 40% more muscle fibers than normal muscled (NM) beef or dairy cattle. Previous work showed that serum from DM fetuses stimulated proliferation of L6 myoblasts to a greater extent than serum from NM fetuses. Although the exact role of insulin-like growth factor-II (IGF-II) in th... | ['Analysis of Variance', 'Animals', 'Blotting, Northern', 'Cattle', 'Embryonic and Fetal Development', 'Immunoblotting', 'Insulin-Like Growth Factor II', 'Liver', 'Muscle, Skeletal', 'RNA, Messenger'] | 7,828,428 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.500.380.271'], ['G07.345.500.325', 'G08.686.784.170'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.644.276.937.420', 'D12.776.124.862.425', 'D12.776.467.937... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nonadherence as 4-day Antiretroviral Therapy Interruptions: Do Depression and Race/Ethnicity Matter as Much in the Modern Antiretroviral Therapy Era? | HIV + White, Latino, and African Americans (N = 1131) completed a survey advertised on social media to re-examine the effect of depressive symptoms (via the Patient Health Questionnaire; PHQ-9) and race/ethnicity on antiretroviral therapy nonadherence (defined as past 3-month, 4-day treatment interruption). An adjusted... | ['Adult', 'African Americans', 'Anti-HIV Agents', 'Depressive Disorder', 'European Continental Ancestry Group', 'Female', 'HIV Infections', 'Health Surveys', 'Hispanic Americans', 'Humans', 'Male', 'Medication Adherence', 'Middle Aged', 'Odds Ratio', 'Psychometrics', 'Surveys and Questionnaires', 'United States'] | 26,767,532 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['D27.505.954.122.388.077.088'], ['F03.600.300'], ['M01.686.508.400'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms. | BACKGROUND: Telomere/telomerase system has been recently recognized as an attractive target for anticancer therapy. Telomerase inhibition results in tumor regression and increased sensitivity to various cytotoxic drugs. However, it has not been fully established yet whether the mediator of these effects is telomerase i... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Cell Line, Tumor', 'Cell Movement', 'Cell Survival', 'Cisplatin', 'Comet Assay', 'DNA Damage', 'DNA Repair', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'K562 Cells', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Neoplasms', 'Oligonucleotides', 'Tel... | 20,161,752 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['G02.111.222', 'G05.219'], ['G07... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Triage, transportation, and destination decisions by out-of-hospital emergency care providers. | INTRODUCTION: The effectiveness of a tiered emergency medical services system often hinges upon the ability of initial care providers with little or no formal training to identify emergent patient needs and determine the best means to meet those needs.OBJECTIVES: To determine if out-of-hospital emergency care providers... | ['Caregivers', 'Decision Making', 'Emergency Medical Services', 'Emergency Medical Technicians', 'Humans', 'Statistics, Nonparametric', 'Surveys and Questionnaires', 'Transportation of Patients', 'Triage', 'Workforce'] | 10,346,404 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F02.463.785.373'], ['N02.421.297'], ['M01.526.373.250', 'M01.526.485.067.150', 'N02.360.067.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.850.520.830.995'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pancreatic abscess. Extraperitoneal drainage]. | The pancreatic abscess occurs in two to six per cent of patients with acute pancreatitis and in 40 to 50 per cent of whom develop the severe form of the disease. The postoperative morbidity rate is 85 to 90 per cent and the mortality rate is 30 to 50 per cent due to persistence or recurrence of infection. The anatomica... | ['Abscess', 'Adolescent', 'Adult', 'Aged', 'Drainage', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Diseases'] | 2,756,275 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cell-free expression of protein complexes for structural biology. | Cell-free protein synthesis is advantageous for the expression of protein complexes, since it is suitable for the co-expression of two or more components of the target protein complexes. The quantity and the quality of cell-free expressed complexes are generally better than those of protein complexes expressed in conve... | ['Crystallography, X-Ray', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Gene Expression', 'Models, Molecular', 'Multiprotein Complexes', 'Protein Conformation', 'Recombinant Fusion Proteins', 'Viral Proteins'] | 24,203,330 | [['E05.196.309.742.225'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['E05.599.595'], ['D05.500'], ['G02.111.570.820.709'], ['D12.776.828.300'], ['D12.776.964']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epidermal growth factor receptor defects in leprechaunism. A multiple growth factor-resistant syndrome. | Leprechaunism is a rare genetic disorder characterized by severe growth retardation and insulin resistance. Maximal epidermal growth factor (EGF) binding was reduced in fibroblasts from three unrelated patients with leprechaunism (Ark-1, Can-1, and Minn-1) compared with control (0.8-2.2%/mg protein vs. 5.5%/mg protein)... | ['Drug Resistance', 'Epidermal Growth Factor', 'ErbB Receptors', 'Fibroblasts', 'Growth Disorders', 'Humans', 'Insulin Resistance', 'Phosphorylation', 'Protein Kinase C', 'Receptor, Insulin', 'Sphingosine'] | 2,808,704 | [['G07.690.773.984'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['A11.329.228'], ['C23.550.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500', 'G07.6... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An aggregate score to stratify the technical complexity of video-assisted thoracoscopic lobectomy. | OBJECTIVES: The purpose of this study was to develop a score to predict the complexity of video-assisted thoracoscopic surgery (VATS) lobectomies preoperatively.METHODS: One hundred and thirty-nine consecutive patients undergoing VATS lobectomy operated on by a single surgeon as the first operator were included. Comple... | ['Aged', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Operative Time', 'Pneumonectomy', 'Thoracic Surgery, Video-Assisted'] | 30,500,910 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['E04.620', 'E04.928.600.600'], ['E01.370.388.250.840.830', 'E01.370.388.250.950.830', 'E04.502.250.840.830', 'E04.502.250.950.830', 'E04.928.752.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of iron absorption from single meals and daily diets using radioFe (55Fe, 59Fe). | The purpose of the present study was to compare two measures of Fe absorption, one from single meals and the other from daily diets. Ten ileostomy subjects were given the same low-fibre composite diet for all three meals each day for five consecutive days. After 3 weeks the experiment was repeated with a high-fibre die... | ['Adult', 'Aged', 'Dietary Fiber', 'Dietetics', 'Female', 'Ferritins', 'Hemoglobins', 'Humans', 'Ileostomy', 'Intestinal Absorption', 'Iron', 'Iron Radioisotopes', 'Male', 'Middle Aged', 'Sensitivity and Specificity'] | 8,785,204 | [['M01.060.116'], ['M01.060.116.100'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['H02.533.290'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['G03.015.500.374.500', 'G03.787... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
The polyphyletic genus Sebaea (Gentianaceae): a step forward in understanding the morphological and karyological evolution of the Exaceae. | Within the Gentianaceae-Exaceae, the most species-rich genus Sebaea has received very little attention in terms of phylogenetic or karyological investigations. As a result, the exact number of species remains vague and the relationships with the other members of the Exaceae poorly understood. In this paper, we provide ... | ['Bayes Theorem', 'DNA, Chloroplast', 'DNA, Plant', 'Evolution, Molecular', 'Flowers', 'Gentianaceae', 'Karyotyping', 'Models, Genetic', 'Phylogeny', 'Sequence Alignment', 'Sequence Analysis, DNA'] | 19,646,540 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['D13.444.308.283.170', 'D13.444.308.435.275'], ['D13.444.308.435'], ['G05.045.250', 'G16.075.250'], ['A18.024.249.500'], ['B01.650.940.800.575.912.250.456.750'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.39... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Buried penis: congenital syndrome of a short penile shaft and a paucity of penile shaft skin. | PURPOSE: The term "buried penis" has been applied to a variety of penile abnormalities and includes an apparent buried penis that is obvious at birth. The purpose of this study was to examine prospectively the congenital buried penis and to evaluate an operative technique for its management.MATERIALS AND METHODS: A tot... | ['Child, Preschool', 'Humans', 'Infant', 'Male', 'Penis', 'Prospective Studies', 'Urologic Surgical Procedures, Male'] | 15,821,566 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A05.360.444.492'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E04.950.774.860']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gene flow from single and stacked herbicide-resistant rice (Oryza sativa): modeling occurrence of multiple herbicide-resistant weedy rice. | BACKGROUND: Provisia™ rice (PV), a non-genetically engineered (GE) quizalofop-resistant rice, will provide growers with an additional option for weed management to use in conjunction with Clearfield® rice (CL) production. Modeling compared the impact of stacking resistance traits versus single traits in rice on introgr... | ['Gene Flow', 'Herbicide Resistance', 'Herbicides', 'Models, Genetic', 'Oryza', 'Plant Weeds'] | 28,834,651 | [['G05.330.159'], ['G07.690.773.984.443'], ['D27.720.031.700.366', 'D27.888.723.366'], ['E05.599.395.397'], ['B01.650.940.800.575.912.250.822.616'], ['B01.650.449']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation. | Luminopsins are fusion proteins of luciferase and opsin that allow interrogation of neuronal circuits at different temporal and spatial resolutions by choosing either extrinsic physical or intrinsic biological light for its activation. Building on previous development of fusions of wild-type Gaussia luciferase with cha... | ['Action Potentials', 'Animals', 'Behavior, Animal', 'Female', 'HEK293 Cells', 'Humans', 'Light', 'Luciferases', 'Luminescent Measurements', 'Mice, Inbred C57BL', 'Movement', 'Neurons', 'Opsins', 'Optogenetics', 'Rats, Sprague-Dawley', 'Rhodopsin', 'Substantia Nigra', 'Synapses', 'Volvox'] | 26,733,686 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F01.145.113'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D08.811.682.517', 'D12.776.532.510'], ['E05.196.712.516'], ['B01.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cement as a risk factor for deep-vein thrombosis. Comparison of cemented TKR, uncemented TKR and cemented THR. | A total of 110 total knee replacements (TKRs) was randomised to receive either a cemented or an uncemented prosthesis. Postoperative venography at five to seven days was used to compare the prevalence, site and size of deep-vein thrombosis (DVT). We also compared the findings with those of postoperative venography in a... | ['Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Bone Cements', 'Cementation', 'Follow-Up Studies', 'Humans', 'Incidence', 'Phlebography', 'Postoperative Care', 'Prevalence', 'Risk Factors', 'Thrombophlebitis'] | 9,699,821 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['E05.170', 'E06.095.170'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Models of intracranial aneurysms for angiographic imaging modalities. A technical note]. | OBJECTIVE: To delineate technical aspects of vascular models with intracranial aneurysm in vitro production, suitable for angiographic imaging.MATERIAL AND METHODS: Wax (K2 exact, S-U-CERAMO-CAPS-WAX), Girtl's mass, gelatin, and silicone (Silicone 10015 Den Braven, Elastosil 7683/25, Elite Double 32 Shore-A, Rema-Sil) ... | ['Angiography', 'Carotid Arteries', 'Cerebral Arteries', 'Humans', 'Intracranial Aneurysm', 'Models, Anatomic', 'Silicones'] | 17,768,371 | [['E01.370.350.700.060', 'E01.370.370.050'], ['A07.015.114.186'], ['A07.015.114.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['D02.756.650.700', 'D05.750.900.850', 'D25.720.900.850',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[PTEN tumor suppressor gene combined with doxycycline inhibites telomerase activity in human mucoepidermoid carcinoma cell line]. | OBJECTIVE: To investigate the effect of PTEN tumor suppressor gene combined with doxycycline on telomerase activity in human mucoepidermoid carcinoma cell line.METHODS: The wild-type PTEN tumor suppressor gene or empty vector was introduced into mucoepidermoid carcinoma cell line in vitro, then the cancer cells were tr... | ['Carcinoma, Mucoepidermoid', 'Cell Line', 'Cell Line, Tumor', 'Doxycycline', 'Genes, Tumor Suppressor', 'Genetic Vectors', 'Humans', 'PTEN Phosphohydrolase', 'Telomerase', 'Transfection'] | 21,179,692 | [['C04.557.470.200.025.340', 'C04.557.470.590.340'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.65... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Supervised oral HIV self-testing is accurate in rural KwaZulu-Natal, South Africa. | OBJECTIVES: To achieve UNAIDS 90-90-90 targets, alternatives to conventional HIV testing models are necessary in South Africa to increase population awareness of their HIV status. One of the alternatives is oral mucosal transudates-based HIV self-testing (OralST). This study describes implementation of counsellor-intro... | ['AIDS Serodiagnosis', 'Adolescent', 'Adult', 'Ambulatory Care Facilities', 'Antibodies', 'Awareness', 'Cross-Sectional Studies', 'Diagnostic Self Evaluation', 'Female', 'HIV', 'HIV Infections', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Mouth Mucosa', 'Primary Health Care', 'Reproducibility of Results', 'Rura... | 27,098,272 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.057'], ['M01.060.116'], ['N02.278.035'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['F02.463.188.150'], ['E05.318.372.500.875', 'N05.715.360.33... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Relationship of the first step in protein synthesis to ppGpp: formation of A(5')ppp(5')Gpp. | In the presence of purified Escherichia coli lysyl-tRNA synthetase [L-lysine:tRNALys ligase (AMP-forming) EC 6.1.1.6], L-lysine, and ATP, addition of the nucleotide ppGpp results in formation of a unique product-A(5')ppp(5') Gpp. The same compound is also formed very rapidly in a cell-free protein-synthesizing system w... | ['Adenine Nucleotides', 'Adenosine Triphosphate', 'Alkaline Phosphatase', 'Avian Myeloblastosis Virus', 'Bacterial Proteins', 'Chromatography, DEAE-Cellulose', 'Chromatography, Thin Layer', 'Escherichia coli', 'Guanine Nucleotides', 'Lysine-tRNA Ligase', 'Phosphoric Diester Hydrolases', 'Protein Biosynthesis', 'RNA, Vi... | 170,611 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D08.811.277.352.650.035'], ['B04.613.807.070.110', 'B04.820.650.070.110'], ['D12.776.097'], ['E05.196.181.400.383.349'], ['E05.196.181.400.537'], ['B03.440.450.425.325.300... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of biofilm-forming capacity of Moraxella bovis, the primary causative agent of infectious bovine keratoconjunctivitis. | The difficulties in preventing and treating infectious bovine keratoconjunctivitis (IBK) and the consequent impact on the cattle industry worldwide emphasize the need to better understand this infectious process along with the biology of Moraxella bovis, its primary causative agent. Although there is increasing evidenc... | ['Animals', 'Biofilms', 'Cattle', 'Cattle Diseases', 'Keratoconjunctivitis, Infectious', 'Moraxella bovis', 'Moraxellaceae Infections'] | 23,907,059 | [['B01.050'], ['A20.593', 'G06.120'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C01.150.252.289.450', 'C01.375.354.450', 'C11.187.183.394.520', 'C11.204.564.585.500', 'C11.294.354.450', 'C22.500'], ['B03.440.400.425.537.525.500', 'B03.660.250.530.525.500'], ['C01.150.252.400.560']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Involving young people in health service delivery. | Young people are entitled to be involved in decisions about their health care, yet many are not engaged in any meaningful way. This article outlines the approach taken by Newcastle Upon Tyne Hospitals NHS Foundation Trust and partners to implement quality criteria for young people-friendly health services. It describes... | ['Adolescent', 'Adult', 'Delivery of Health Care', 'Humans', 'State Medicine', 'United Kingdom', 'Young Adult'] | 23,617,061 | [['M01.060.057'], ['M01.060.116'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363'], ['M01.060.116.815']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Retrospective assessment of premenstrual changes in Icelandic women. | The purpose of this study was to increase our knowledge of the condition of Icelandic women aged 29 to 40 years during the premenstrual phase of the menstrual cycle. Premenstrual symptoms were measured by a retrospective instrument adapted from Halbreich and colleagues' Premenstrual Assessment Form. Our findings showed... | ['Adult', 'Female', 'Humans', 'Iceland', 'Nursing Assessment', 'Premenstrual Syndrome', 'Retrospective Studies', 'Self Care', 'Surveys and Questionnaires'] | 1,885,341 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.249', 'Z01.639.490'], ['N04.590.233.508.480'], ['C23.550.568.968'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.75... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Serum concentration modifies amplitude and kinetics of voltage-gated Na+ current in the Mat-LyLu cell line of rat prostate cancer. | Voltage-gated Na+ channel (VGSC) expression has previously been shown to be upregulated in strongly metastatic prostate cancer cells (rat and human) and its activity shown to potentiate a variety of cellular behaviours integral to the metastatic cascade. However, the mechanism(s) responsible for the Na+ channel upregul... | ['Animals', 'Cattle', 'Cell Line, Tumor', 'Electric Conductivity', 'Fetal Blood', 'Male', 'Patch-Clamp Techniques', 'Prostatic Neoplasms', 'Rats', 'Sodium Channels', 'Tetrodotoxin'] | 15,109,569 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210.190', 'A11.251.860.180'], ['G01.358.500.249.277'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['E05.200.500.905', 'E05.242.800'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statistical signatures of a targeted search by bacteria. | Chemoattractant gradients are rarely well-controlled in nature and recent attention has turned to bacterial chemotaxis toward typical bacterial food sources such as food patches or even bacterial prey. In environments with localized food sources reminiscent of a bacterium's natural habitat, striking phenomena-such as t... | ['Bacteria', 'Bacterial Physiological Phenomena', 'Chemotactic Factors', 'Chemotaxis', 'Models, Biological'] | 28,809,162 | [['B03'], ['G06.099'], ['D23.125'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['E05.599.395']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biomimetic mineralization of metal-organic frameworks around polysaccharides. | Biomimetic mineralization exploits natural biomineralization processes for the design and fabrication of synthetic functional materials. Here, we report for the first time the use of carbohydrates (polysaccharides) for the biomimetic crystallization of metal-organic frameworks. This discovery greatly expands the potent... | ['Biomimetic Materials', 'Metal-Organic Frameworks', 'Particle Size', 'Polysaccharides'] | 28,067,353 | [['J01.637.087'], ['D02.691.638', 'D05.750.215'], ['G02.712'], ['D09.698']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Resistance to Eimeria bovis produced after chemotherapy of experimental infections in calves. | Eighteen Holstein-Friesian four week old calves were inoculated with 5 X 10(5) sporocysts of Eimeria bovis by stomach tube. The calves were divided into three equal groups. The first group was treated with monensin, 1 mg kg-1 body weight daily, from the 10th-20th day inclusive after infection; the second group was trea... | ['Amprolium', 'Animals', 'Animals, Newborn', 'Cattle', 'Cattle Diseases', 'Coccidiosis', 'Eimeria', 'Feces', 'Female', 'Furans', 'Male', 'Monensin', 'Parasite Egg Count', 'Picolines'] | 7,201,191 | [['D03.383.725.676.152'], ['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C01.610.752.250'], ['B01.043.075.189.250.250.250'], ['A12.459'], ['D03.383.312'], ['D03.383.312.600'], ['E01.370.225.932.600', 'E05.200.932.600'], ['D03.383.725.676']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stalking on campus: the prevalence and strategies for coping with stalking. | This epidemiological study explored the prevalence of stalkers and stalking victims among college students. Two questionnaires (one assessing the behaviors of those who stalk others, and the other assessing victims of stalking) were administered to 294 college undergraduates. The questionnaires were then revised and re... | ['Adaptation, Psychological', 'Adult', 'Crime Victims', 'Female', 'Humans', 'Male', 'Prevalence', 'Retrospective Studies', 'Sexual Harassment', 'Students', 'Universities'] | 9,243,829 | [['F01.058'], ['M01.060.116'], ['M01.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.82... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Immobilization of mammalian eggs on solid substrates by lectins for electron microscopy. | Cumulus-free, zona pellucida invested hamster and mouse eggs were immobilized by adherence of the zonae to glass or plastic substrates to which the lectin, wheatgerm agglutinin, had been attached. This simple method of egg immobilization enabled processing of very small quantities of eggs for both scanning and transmis... | ['Animals', 'Cell Adhesion', 'Chorionic Gonadotropin', 'Cricetinae', 'Female', 'Gonadotropins, Equine', 'Mesocricetus', 'Mice', 'Mice, Inbred ICR', 'Microscopy, Electron', 'Microscopy, Electron, Scanning', 'Ovum', 'Superovulation', 'Wheat Germ Agglutinins'] | 3,585,995 | [['B01.050'], ['G04.022'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['B01.050.150.900.649.313.992.635.075.250'], ['D06.472.699.322.451', 'D06.472.699.649.451', 'D12.644.548.726.451', 'D12.776.780.451'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['B01.050.150.900.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coping with dehydration: sympathetic activation and regulation of glutamatergic transmission in the hypothalamic PVN. | Autonomic and endocrine profiles of chronic hypertension and heart failure resemble those of acute dehydration. Importantly, all of these conditions are associated with exaggerated sympathetic nerve activity (SNA) driven by glutamatergic activation of the hypothalamic paraventricular nucleus (PVN). Here, studies sought... | ['Adaptation, Psychological', 'Animals', 'Behavior, Animal', 'Blood Pressure', 'Dehydration', 'Dose-Response Relationship, Drug', 'Glutamates', 'Homeostasis', 'Male', 'Models, Animal', 'N-Methylaspartate', 'Paraventricular Hypothalamic Nucleus', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate', 'Sympat... | 24,671,240 | [['F01.058'], ['B01.050'], ['F01.145.113'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C18.452.950.179', 'C23.550.274'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.125.067.625', 'D12.125.119.409'], ['G07.410'], ['E05.598'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['A08.186.211.180.497.342.400', 'A08.186.2... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Household smoking behaviours and exposure to environmental tobacco smoke among infants: are current strategies effectively protecting our young? | OBJECTIVE: To determine the prevalence of infant exposure to environmental tobacco smoke (ETS) among infants attending child health clinics in regional NSW; the association between such exposure and household smoking behaviours; and the factors associated with smoking restrictions in households with infants.METHODS: Pa... | ['Adolescent', 'Adult', 'Cotinine', 'Creatinine', 'Environmental Exposure', 'Family Characteristics', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'New South Wales', 'Parents', 'Prevalence', 'Smoking', 'Tobacco Smoke Pollution', 'Young Adult'] | 20,618,268 | [['M01.060.057'], ['M01.060.116'], ['D03.383.773.812.180'], ['D03.383.129.308.207'], ['N06.850.460.350'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine. | DYT1 dystonia is a severe form of inherited dystonia, characterized by involuntary twisting movements and abnormal postures. It is linked to a deletion in the dyt1 gene, resulting in a mutated form of the protein torsinA. The penetrance for dystonia is incomplete, but both clinically affected and non-manifesting carrie... | ['Acetylcholine', 'Acetylcholinesterase', 'Animals', 'Corpus Striatum', 'Disease Models, Animal', 'Dystonic Disorders', 'Excitatory Postsynaptic Potentials', 'Genotype', 'Mice', 'Mice, Transgenic', 'Molecular Chaperones', 'Neuronal Plasticity', 'Signal Transduction', 'Synapses'] | 19,641,103 | [['D02.092.211.111'], ['D08.811.277.352.100.170.176'], ['B01.050'], ['A08.186.211.200.885.287.249.487'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.662.300'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G05.380'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Variations in digital nerve anatomy. | One hundred digital nerves from 10 cadaver hands were dissected, and branching patterns were analyzed. Contrary to the traditional belief that the digital nerve predictably trifurcates at the distal interphalangeal crease, much variation exists. Terminal branching occurred distal to the crease in 60% of the thumb digit... | ['Cadaver', 'Dissection', 'Evaluation Studies as Topic', 'Fingers', 'Humans', 'Peripheral Nerves'] | 1,430,932 | [['C23.550.260.224'], ['E01.370.225.998.221', 'E04.221', 'E05.200.998.221'], ['E05.337', 'N05.715.360.335'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate. | INTRODUCTION: This work aimed at comparing the production of inflammatory and pro- and anti-angiogenic factors by normal/reactive (N/R) or inflammatory (I) areas of the osteoarthritic synovial membrane. The effects of interleukin (IL)-1â and chondroitin sulfate (CS) on the expression of pro- and anti-angiogenic factors... | ['Aged', 'Aged, 80 and over', 'Cells, Cultured', 'Chondroitin Sulfates', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neovascularization, Pathologic', 'Osteoarthritis', 'Synovial Membrane'] | 22,409,996 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A11.251'], ['D09.698.373.200.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.589.500'], ['C05.550.114.606', 'C05.799.613'], ['A02.835.583.443.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Demonstrating reverence for the earth. | As a community hospital and a major employer, St. Mary's Hospital Medical Center in Green Bay, Wisconsin, assumes responsibility not only for the health of people in the community but also for the health of the environment in which they live. Demonstrating reverence for the earth is a primary strategic goal, originatin... | ['Awards and Prizes', 'Conservation of Energy Resources', 'Illinois', 'Maintenance and Engineering, Hospital', 'Medical Waste Disposal', 'Mercury Poisoning', 'Multi-Institutional Systems', 'Organizational Case Studies', 'Refuse Disposal', 'Wisconsin'] | 18,831,189 | [['K01.150'], ['N06.230.080.078'], ['Z01.107.567.875.350.350', 'Z01.107.567.875.510.350'], ['N02.278.216.500.968.450', 'N02.628.472', 'N04.452.442.452.422.450'], ['D20.944.460.300', 'N06.850.460.710.460.300', 'N06.850.860.510.900.600.600'], ['C25.723.522.875'], ['N04.452.540'], ['N03.349.380.710', 'N05.715.360.455'], [... | ['Humanities [K]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The utility of postmortem lung for RNA studies; variability and correlation of the expression of surfactant proteins in human lung. | Postmortem human lung tissue was evaluated for its utility in studies of the mRNAs for the surfactant proteins. Data obtained from different analytical procedures indicated that surfactant protein mRNAs are quite stable in these tissues with a half-life of 10 to 12 h. These analyses revealed no major regional differenc... | ['Cadaver', 'Half-Life', 'Humans', 'Infant, Newborn', 'Lung', 'Nucleic Acid Hybridization', 'Proteins', 'Pulmonary Surfactants', 'RNA', 'RNA, Messenger'] | 1,707,362 | [['C23.550.260.224'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A04.411'], ['E05.393.661', 'G02.111.611'], ['D12.776'], ['D27.505.954.796.600'], ['D13.444.735'], ['D13.444.735.544']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cyclin A1-CDK2 complex regulates DNA double-strand break repair. | Vertebrates express two A-type cyclins; both associate with and activate the CDK2 protein kinase. Cyclin A1 is required in the male germ line, but its molecular functions are incompletely understood. We observed specific induction of cyclin A1 expression and promoter activity after UV and gamma-irradiation which was me... | ['Animals', 'Antigens, Nuclear', 'CDC2-CDC28 Kinases', 'Cells, Cultured', 'Cyclin A', 'Cyclin A1', 'Cyclin-Dependent Kinase 2', 'DNA', 'DNA Damage', 'DNA Repair', 'DNA-Binding Proteins', 'Fibroblasts', 'Gamma Rays', 'Gene Expression Regulation', 'Hematopoietic Stem Cells', 'Humans', 'Ku Autoantigen', 'Macromolecular Su... | 15,456,866 | [['B01.050'], ['D12.776.660.625', 'D23.050.290'], ['D08.811.913.696.620.682.700.646.500.500', 'D12.644.360.250.067', 'D12.776.167.200.067', 'D12.776.476.250.067'], ['A11.251'], ['D12.644.360.262.100', 'D12.776.167.218.100', 'D12.776.476.262.100'], ['D12.644.360.262.100.100', 'D12.776.167.218.100.100', 'D12.776.476.262.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structural and energetic effects of A2A adenosine receptor mutations on agonist and antagonist binding. | To predict structural and energetic effects of point mutations on ligand binding is of considerable interest in biochemistry and pharmacology. This is not only useful in connection with site-directed mutagenesis experiments, but could also allow interpretation and prediction of individual responses to drug treatment. F... | ['Adenosine A2 Receptor Agonists', 'Adenosine A2 Receptor Antagonists', "Adenosine-5'-(N-ethylcarboxamide)", 'Binding Sites', 'Humans', 'Ligands', 'Mutant Proteins', 'Mutation', 'Receptor, Adenosine A2A', 'Thermodynamics', 'Triazines', 'Triazoles'] | 25,285,959 | [['D27.505.519.625.725.200.100.200', 'D27.505.696.577.725.200.100.200'], ['D27.505.519.625.725.400.100.200', 'D27.505.696.577.725.400.100.200'], ['D03.633.100.759.590.138.025', 'D13.570.583.138.025', 'D13.570.800.096.250'], ['G02.111.570.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['D12... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of Staphopain A (ScpA) and B (SspB) precursor activation mechanisms reveals unique secretion kinetics of proSspB (Staphopain B), and a different interaction with its cognate Staphostatin, SspC. | The scpAB and sspABC operons of Staphylococcus aureus encode Staphopain cysteine proteases ScpA and SspB, and their respective Staphostatins ScpB and SspC, which are thought to protect against premature activation of Staphopain precursors during protein export. However, we found that the proSspB precursor was secreted ... | ['Amino Acid Sequence', 'Cysteine Endopeptidases', 'Cytoplasm', 'Elastin', 'Escherichia coli', 'Models, Molecular', 'Molecular Sequence Data', 'Protein Precursors', 'Protein Stability', 'Protein Structure, Tertiary', 'Staphylococcus aureus', 'Substrate Specificity'] | 19,943,908 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['A11.284.430.214'], ['D05.750.078.421', 'D12.776.860.300.350'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.599.595'], ['L01.453.245.667'], ['D12.776.811'], ['G02.111.700'], ['G02.111.570.820.709.610'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Surface electric fields increase osteoblast adhesion through improved wettability on hydroxyapatite electret. | Osteoblasts are susceptible to the surface characteristics of bioceramics and stimulation from outside the cells. The purpose of this study was to evaluate the effects of electrical polarization on surface characteristics and osteoblastic adhesion. The surface characteristics revealed that electrical polarization had n... | ['Animals', 'Cell Adhesion', 'Cell Shape', 'Cells, Cultured', 'Durapatite', 'Electricity', 'Electrowetting', 'Mice', 'Mice, Inbred C57BL', 'Osteoblasts', 'Wettability'] | 20,355,852 | [['B01.050'], ['G04.022'], ['G04.320'], ['A11.251'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['G01.358.500.249'], ['E05.830.666.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three new species of Echinobothrium (Cestoda: Diphyllidea) from Indo-Pacific stingrays of the genus Pastinachus (Rajiformes: Dasyatidae). | Three new species of diphyllidean cestodes are described from stingrays of the genus Pastinachus from the Indian and Pacific Oceans. All three new species differ from all but 10 of the 36 valid species of Echinobothrium van Beneden, 1849 in that they bear lateral hooklets arranged in a continuous band across each later... | ['Animals', 'Cestoda', 'Female', 'Fish Diseases', 'Skates, Fish'] | 20,941,910 | [['B01.050'], ['B01.050.500.500.736.215'], ['C22.362'], ['B01.050.150.900.493.370.870', 'B01.050.150.900.493.378.682']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer. | MicroRNAs (miRNAs) play a critical role in cancer development and progression. Aberrant expression of miR-15a has recently been reported in several cancers, but its role in non-small cell lung cancer (NSCLC) still remains obscure. We investigated the effects of miR-15a on proliferation, apoptosis, and metastasis in A54... | ['Apoptosis', 'Apoptosis Regulatory Proteins', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Proliferation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MicroRNAs', 'Neoplasm Metastasis'] | 25,874,488 | [['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.15... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells. | BACKGROUND: Knowledge about signaling pathways is typically compiled based on data gathered using different cell lines. This approach implicitly assumes that the cell line dependence is not important. However, different cell lines do not always respond to a particular stimulus in the same way, and lack of coherent data... | ['Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Cell Line', 'Epithelial Cells', 'ErbB Receptors', 'Extracellular Signal-Regulated MAP Kinases', 'Humans', 'Mammary Glands, Human', 'Phosphorylation', 'Proto-Oncogene Proteins c-akt', 'Receptor, ErbB-2', 'Receptor, ErbB-3', 'Signal... | 19,878,579 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['A11.251.210'], ['A11.436'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009',... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A case of suicide by double gunshot wounds to the head: the ability to act after the first shot. | A single gunshot (or multiple) does (do) not necessarily lead to immediate loss of consciousness or rapid neurological deficits, so the victim may be able to repeatedly pull the trigger before achieving the lethal effect. Despite multiple gunshot wounds can lead to the suspicious participation of other person to the de... | ['Autopsy', 'Forensic Ballistics', 'Head Injuries, Penetrating', 'Humans', 'Male', 'Meninges', 'Middle Aged', 'Multiple Trauma', 'Skull', 'Suicide, Completed', 'Temporal Lobe', 'Wounds, Gunshot'] | 31,201,500 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['I01.198.780.760'], ['C10.900.300.675', 'C26.915.300.475', 'C26.986.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.566'], ['M01.060.116.630'], ['C26.640'], ['A02.835.232.781'], ['F01.145.126.980.875.800', 'I01.880.735.856.800'], ['A08.186.211.200.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Ability, incentives, and management feedback: organizational change to reduce pressure ulcers in a nursing home. | OBJECTIVE: Quality improvement (QI) processes in nursing homes are highly variable and often ineffective. This study evaluated an innovative QI process to reduce pressure ulcers (PUs) in a nursing home with a high rate of PUs.DESIGN: This was a 48-week, longitudinal study comparing the incidence of PUs during 12-week b... | ['Aged', 'Aptitude', 'Attitude of Health Personnel', 'Clinical Competence', 'Employee Discipline', 'Feedback, Psychological', 'Health Personnel', 'Humans', 'Incidence', 'Inservice Training', 'Longitudinal Studies', 'Motivation', 'Nursing Homes', 'Organizational Culture', 'Organizational Innovation', 'Outcome Assessment... | 16,503,306 | [['M01.060.116.100'], ['F02.784.629.131'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N04.452.677.358'], ['F01.058.288', 'F04.754.308'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Inferior Turbinate Swing Technique: A Novel Surgical Route to Approach Maxillary Sinus Area Pathology. | The inferior turbinate is an important structure for maintenance of adequate physiologic function within the nasal cavity. However, it hampers access to lesions involving maxillary sinus areas, including postoperative mucocele or benign tumor, and acts as an inferior limit to widening the natural ostium of a maxillary ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Endoscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Maxillary Sinus', 'Maxillary Sinus Neoplasms', 'Maxillary Sinusitis', 'Middle Aged', 'Papilloma, Inverted', 'Patient Safety', 'Prospective Studies', 'Tomography, X-Ray Computed', 'Treatment Outcome', ... | 29,944,454 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.388.250', 'E04.502.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
What is Ebola? | On 23 March 2014, the World Health Organization first announced a new Ebola virus outbreak that started in December 2013 in the eastern part of the Republic of Guinea. Human infections shortly emerged in Liberia, Sierra Leone, and Nigeria. On 30 September 2014, the Centers for Disease Control and Prevention confirmed t... | ['Africa, Western', 'Disease Outbreaks', 'Ebolavirus', 'Hemorrhagic Fever, Ebola', 'Humans', 'Risk Factors', 'Travel'] | 25,496,121 | [['Z01.058.290.190'], ['N06.850.290'], ['B04.820.480.937.300.200'], ['C01.925.782.417.415', 'C01.925.782.580.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['I03.883']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Leaching of Cu and Zn from discarded boat paint particles into tap water and rain water. | We studied the leaching of copper and zinc from particles of discarded boat paint added to tap water (pH 7.3) and rain water (pH=4.7), simulating conditions encountered during the hosing or runoff of antifouling waste. Leaching rates appeared to be diffusion-controlled and were greater in rain water than in tap water a... | ['Copper', 'Disinfectants', 'Environmental Monitoring', 'Fresh Water', 'Hydrogen-Ion Concentration', 'Paint', 'Rain', 'Ships', 'Water Pollutants, Chemical', 'Water Supply', 'Zinc'] | 21,300,396 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D27.505.954.122.425', 'D27.720.274'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.280', 'N06.230.232'], ['G02.300'], ['J01.637.597'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Tall cell variant of papillary thyroid carcinoma: a population-based study in Iceland. | BACKGROUND: The tall cell variant (TCV) of papillary thyroid carcinoma (PTC) is an aggressive variant of PTC that is believed to have worse outcomes than classical PTC. The objective of this study was to investigate the incidence, survival, and disease recurrence of patients with TCV and compare them with other PTC in ... | ['Adolescent', 'Adult', 'Age of Onset', 'Aged', 'Aged, 80 and over', 'Carcinoma, Papillary', 'Female', 'Humans', 'Iceland', 'Incidence', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Sex Factors', 'Survival Rate', 'Thyroid Neoplasms', 'Young Adult'] | 25,322,334 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.249', 'Z01.639.490'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.85... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A successful protocol for the use of pulse oximetry to classify arterial oxygenation into four fuzzy categories. | Pulse oximetry is widely used in critical care medicine to noninvasively estimate arterial hemoglobin oxygen saturation. Despite the obvious benefits of using pulse oximetry to detect life threatening desaturations, it is unknown how well pulse oximetry is able to predict the finer graduations of arterial oxygenation n... | ['Clinical Protocols', 'Decision Making, Computer-Assisted', 'Fuzzy Logic', 'Humans', 'Oximetry', 'Oxygen', 'Prospective Studies', 'Software Design'] | 8,563,278 | [['E02.183', 'N05.715.360.330.125'], ['L01.313.500.750.100'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.124.100.100.600'], ['D01.268.185.550', 'D01.362.670'], ['E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Humanities [K]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Real data o viral hepatitis C therapy in the Czech Republic]. | We reported the first real data about efficacy of interferon-free therapy of chronic hepatitis C in the Czech Republic. Patients were treated with combined therapy of paritaprevir/ritonavir + ombitasvir + dasabuvir with or without ribavirin. There were 109 patients, predominantly men - 62 (57 %), most of them infected ... | ['Anilides', 'Antiviral Agents', 'Carbamates', 'Czech Republic', 'Drug Therapy, Combination', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Macrocyclic Compounds', 'Male', 'Ribavirin', 'Ritonavir', 'Sulfonamides', 'Sustained Virologic Response', 'Uracil'] | 27,723,987 | [['D02.065.199', 'D02.092.146.113'], ['D27.505.954.122.388'], ['D02.241.081.251'], ['Z01.542.248.395'], ['E02.319.310'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Psychophysical and neuroimaging responses to moving stimuli in a patient with the Riddoch phenomenon due to bilateral visual cortex lesions. | Patients with injury to early visual cortex or its inputs can display the Riddoch phenomenon: preserved awareness for moving but not stationary stimuli. We provide a detailed case report of a patient with the Riddoch phenomenon, MC. MC has extensive bilateral lesions to occipitotemporal cortex that include most early v... | ['Blindness, Cortical', 'Brain Mapping', 'Cerebral Infarction', 'Contrast Sensitivity', 'Discrimination, Psychological', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Motion Perception', 'Neuroimaging', 'Psychophysics', 'Visual Cortex', 'Visual Perception'] | 29,753,019 | [['C10.597.751.941.162.250', 'C11.966.075.250', 'C23.888.592.763.941.162.250'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Attachment, invasion, chemotaxis, and proteinase expression of B16-BL6 melanoma cells exhibiting a low metastatic phenotype after exposure to dietary restriction of tyrosine and phenylalanine. | We previously reported that low levels of tyrosine (Tyr) and phenylalanine (Phe) alter the metastatic phenotype of B16-BL6 (BL6) murine melanoma and select for tumor cell populations with decreased lung colonizing ability. To more specifically characterize the effects of Tyr and Phe restriction on the malignant phenoty... | ['Animals', 'Cell Adhesion', 'Chemotaxis', 'Diet', 'Melanoma, Experimental', 'Metalloendopeptidases', 'Mice', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Phenylalanine', 'Plasminogen Activators', 'Receptors, Fibronectin', 'Tyrosine'] | 8,605,726 | [['B01.050'], ['G04.022'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['G07.203.650.240'], ['C04.557.465.625.650.510.525', 'C04.557.580.625.650.510.525', 'C04.557.665.510.525', 'C04.619.600', 'E05.598.500.496.937'], ['D08.811.277.656.300.480', 'D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemorrhagic bullous lesions in a child with Henoch-Sch?nlein purpura. | An 8-year-old boy with Henoch-Sch?nlein purpura who developed hemorrhagic bullae is described. The occurrence of hemorrhagic bullae in children with Henoch-Sch?nlein purpura is rare. A perusal of the literature revealed but seven occurrences to which we add another one. | ['Blister', 'Child', 'Diagnosis, Differential', 'Hemorrhage', 'Humans', 'Male', 'Purpura, Schoenlein-Henoch'] | 16,650,222 | [['C17.800.865.187', 'C23.300.122'], ['M01.060.406'], ['E01.171'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.940.777', 'C15.378.100.802.375', 'C15.378.463.515.580', 'C20.543.520.600', 'C23.550.414.950.375', 'C23.888.885.687.375']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Short- and long-term association of lipid-lowering drug treatment and cardiovascular disease by estimated absolute risk in the Second Australian National Blood Pressure study. | BACKGROUND: There is currently insufficient evidence to support the use of lipid-lowering drug treatment (LLT) for primary prevention of cardiovascular disease (CVD) in the elderly.OBJECTIVES: We examined the relationship of early initiation of LLT with short- and long-term all-cause and CVD mortality in persons older ... | ['Aged', 'Aged, 80 and over', 'Anticholesteremic Agents', 'Australasia', 'Blood Pressure', 'Cardiovascular Diseases', 'Cohort Studies', 'Enalapril', 'Female', 'Humans', 'Hydrochlorothiazide', 'Male', 'Numbers Needed To Treat', 'Primary Prevention', 'Risk', 'Survival Analysis', 'Time Factors'] | 30,293,937 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['Z01.678.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D12.644.456.345.360'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hodgkin's disease in married couples. | The case of a husband and wife who both developed Hodgkin's disease of the same cellular subtype is reported. This represents only the fifth reported case of marital Hodgkin's disease that is well-documented histologically. The relevant literature and potential implications are reviewed. | ['Adult', 'Female', 'Hodgkin Disease', 'Humans', 'Male', 'Marriage'] | 3,986,745 | [['M01.060.116'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308.500.500']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Biological evaluation of cryptophycin 52 fragment A analogues: effect of the multidrug resistance ATP binding cassette transporters on antitumor activity. | Cryptophycin 52 (LY355703) is a potent antiproliferative analogue of the marine natural product cryptophycin 1. It has been shown to have a broad range of antitumor activity against human tumor xenografts and murine tumors including tumors resistant to Taxol and Adriamycin. Its mechanism of action involves arresting ce... | ['ATP-Binding Cassette Transporters', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Depsipeptides', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Humans', 'Lactams', 'Lactones', 'Xenograft Model Antitumor Assays'] | 15,367,700 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['D04.345.566.297', 'D12.644.641.297'], ['G07.690.773.984.300'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589', 'D03.383.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unilateral ureteral obstruction induces DNA repair by APE1. | Ureteral obstruction is associated with oxidative stress and the development of fibrosis of the kidney parenchyma. Apurinic/apyrimidinic endonuclease (APE1) is an essential DNA repair enzyme for repair of oxidative DNA lesions and regulates several transcription factors. The aim of the present study was to investigate ... | ['Animals', 'Collagen Type I', 'DNA Repair', 'DNA-(Apurinic or Apyrimidinic Site) Lyase', 'Disease Models, Animal', 'Fibronectins', 'Fibrosis', 'Gene Expression Regulation', 'Heme Oxygenase-1', 'Kidney', 'Male', 'Oxidative Stress', 'Rats', 'Rats, Wistar', 'Ureteral Obstruction'] | 26,608,791 | [['B01.050'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['G02.111.222', 'G05.219'], ['D08.811.074.750', 'D08.811.520.241.225'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['C23.550.355'], ['G05.308'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumor necrosis factor-alpha impairs endothelium-dependent relaxation of rat renal arteries, independent of tyrosine kinase. | We hypothesized that tumor necrosis factor-alpha (TNF-alpha) mimics endotoxin in attenuating endothelium-dependent vasodilation and smooth muscle constriction of rat renal arteries, and that tyrosine kinase is involved. Isolated rat renal arteries (n =6 per group), pretreated for 2 h by genistein (4',5,7-trihydroxyisof... | ['Acetylcholine', 'Animals', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'Genistein', 'In Vitro Techniques', 'Male', 'Muscle Relaxation', 'Muscle, Smooth, Vascular', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Norepinephrine', 'Potassium Chloride', 'Protein-Tyrosine Kinases', 'Rats', 'Rats, Wistar', 'R... | 12,022,760 | [['D02.092.211.111'], ['B01.050'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.389'], ['D03.383.663.283.266.450.400.375', 'D03.633.100.150.266.450.400.375'], ['E05.481'], ['G11.427.494.554'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D08.811.682.664.500.772'], ['D08.811.682.664.500.772.500'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leflunomide in systemic onset Juvenile idiopathic arthritis. | Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-a blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide... | ['Antirheumatic Agents', 'Arthritis, Juvenile', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Isoxazoles', 'Leflunomide', 'Male'] | 23,024,081 | [['D27.505.954.329'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.385'], ['D03.383.129.385.475']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Two cases of Gymnophalloides seoi infection accompanied by diabetes mellitus. | Gymnophalloides seoi, a new intestinal trematode of humans transmitted by oysters on a southwestern island of Korea, drew medical attentions because of its possible relationship with evoking pancreatitis or other pancreatic diseases. We experienced two interesting cases of G. seoi infection who were accompanied with di... | ['Animals', 'Diabetes Complications', 'Female', 'Humans', 'Intestinal Diseases, Parasitic', 'Male', 'Middle Aged', 'Trematoda', 'Trematode Infections'] | 7,735,787 | [['B01.050'], ['C19.246.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.432', 'C06.405.469.452'], ['M01.060.116.630'], ['B01.050.500.500.736.715'], ['C01.610.335.865']] | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer. | We describe a fully automated, spectrophotometric assay of free and total carnitine in plasma ultrafiltrates. The method, suitable for routine application in most hospital laboratories, incorporates the hydrolysis of acylcarnitines to free carnitine within the program of a Cobas Fara II centrifugal analyzer. The hydrol... | ['Acetylcarnitine', 'Acyl-CoA Dehydrogenase', 'Autoanalysis', 'Carnitine', 'Fatty Acid Desaturases', 'Humans', 'Hydrolysis', 'Mass Spectrometry', 'Quality Control', 'Spectrophotometry'] | 1,424,113 | [['D02.092.877.883.099.090'], ['D08.811.682.660.150.100', 'D12.776.331.099'], ['E05.059'], ['D02.092.877.883.099'], ['D08.811.682.690.708.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['E05.196.566'], ['J01.897.608'], ['E05.196.712.726', 'E05.196.867.826']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Living alone but eating together: Exploring lunch clubs as a dining out experience. | Dining out is most often associated with pleasure and gratification, principally since it presents opportunities for sociability. However, access to dining out experiences is influenced by multiple factors, including age. Little is known about the dining out habits of older people. In particular, the food practices of ... | ['Aged', 'Attitude', 'Feeding Behavior', 'Female', 'Food Services', 'Humans', 'Interpersonal Relations', 'Lunch', 'Male', 'Pleasure', 'Qualitative Research', 'Scotland', 'Surveys and Questionnaires'] | 28,279,689 | [['M01.060.116.100'], ['F01.100'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['J01.576.423.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['G07.203.300.590.560', 'J02.500.590.560'], ['F01.470.867', 'F02.830.816.492'], ['H01.770.644.241.850'], ['Z01.542.363.766'], ['E05.318.308.980... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
Nanotransformation of the haemotrophic Mycoplasma suis during in vitro cultivation attempts using modified cell free Mycoplasma media. | Mycoplasma suis belongs to haemotrophic mycoplasmas (HMs) which cause infectious anaemia in a large variety of mammals. To date, no in vitro cultivation system for M. suis or other HMs has been established. We hypothesised that M. suis could grow in classical Mycoplasma media supplemented with nutrients (e.g. glucose, ... | ['Anemia', 'Animals', 'Erythrocytes', 'Hemoglobins', 'Mycoplasma', 'Mycoplasma Infections', 'Swine', 'Swine Diseases'] | 22,682,998 | [['C15.378.071'], ['B01.050'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B03.440.860.580.553.553'], ['C01.150.252.400.610.610'], ['B01.050.150.900.649.313.500.880'], ['C22.905']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pyoderma Gangrenosum: A Critical Appraisal. | GENERAL PURPOSE: To provide information about pyoderma gangrenosum (PG), including pathophysiology, diagnostic criteria, and treatment.TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.LEARNING OB... | ['Diagnosis, Differential', 'Humans', 'Practice Guidelines as Topic', 'Pyoderma Gangrenosum', 'Skin Diseases, Infectious', 'Skin Ulcer'] | 29,140,836 | [['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['C17.800.695.675', 'C17.800.862.675', 'C17.800.893.675'], ['C01.800', 'C17.800.838'], ['C17.800.893']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Virulence and immunogenicity in experimental animals of Bacillus anthracis strains harbouring or lacking 110 MDa and 60 MDa plasmids. | A comparative study was made of the virulence and immunogenicity in mice or guinea pigs of Bacillus anthracis strains harbouring 110 MDa and/or 60 MDa plasmids. Strains cured of the 110 MDa or the 60 MDa plasmid were more than 100-fold less virulent to mice than were the parental strains harbouring these plasmids. Guin... | ['Animals', 'Bacillus anthracis', 'Guinea Pigs', 'Mice', 'Plasmids', 'Virulence'] | 3,086,499 | [['B01.050'], ['B03.300.390.400.158.218.151', 'B03.353.500.100.218.151', 'B03.510.100.100.218.151', 'B03.510.415.400.158.218.151', 'B03.510.460.410.158.218.151'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.360.600'], ['G06.930']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electro-immunoabsorption in gel, application to enzyme studies (alpha- and beta-amylases from barley). | A technique combining immunoabsorption, electrophoresis and enzymatic characterization reactions in the same gel medium is described using alpha- and beta-amylases from barley seeds, their corresponding immune sera, and alpha-amylases from bacteria. The sensitivity and the specificity of the technique have been determi... | ['Amylases', 'Animals', 'Antigens', 'Edible Grain', 'Electrophoresis, Agar Gel', 'Hordeum', 'Immune Sera', 'Immunization', 'Immunoassay', 'Rabbits'] | 1,194,675 | [['D08.811.277.450.066'], ['B01.050'], ['D23.050'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['E05.196.401.153', 'E05.301.300.100'], ['B01.650.940.800.575.912.250.822.481'], ['A12.207.152.846.500', 'D12.776.124.486... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Acute aortic regurgitation secondary to disk embolization of a Bj?rk-Shiley prosthetic aortic valve. | Having passed the 30th anniversary of the first implantation of a Bj?rk-Shiley convexo-concave tilting mechanical valve, recognition of the life-threatening complication of strut fracture is not widespread. The authors report the case of a 48-year-old man with acute-onset chest pain and dyspnea found to have strut frac... | ['Acute Disease', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Echocardiography', 'Embolism', 'Equipment Failure Analysis', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Prosthesis Failure'] | 20,708,374 | [['C23.550.291.125'], ['A07.541.510.110'], ['C14.280.484.048.500'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.907.355.350'], ['E05.325.192'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767.865', 'E05.325.771']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Medical rehabilitation of the patients with spinal cord injury caused by aortic aneurysm and its operation. | OBJECTIVES: To determine the natural course of spinal cord injury (SCI) after aortic aneurysm surgery.SETTING: Acute care and semi-acute wards in Osaka Rosai Hospital, Japan.METHODS: From 1998 to 2003, 12 patients with thoracic SCI (eight men and four women; mean age: 69 years) were enrolled and evaluated by the Americ... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm', 'Female', 'Humans', 'Male', 'Middle Aged', 'Paralysis', 'Pneumonia, Aspiration', 'Pressure Ulcer', 'Recovery of Function', 'Renal Insufficiency', 'Spinal Cord Injuries', 'Vascular Surgical Procedures'] | 17,471,292 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239', 'C14.907.109.139'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.622', 'C23.888.592.636'], ['C01.748.610.529', 'C08.381.677.529', 'C08.730.610.529'], ['C17.800.893.665'], ['G16.757'], ['C12.777.419.780', 'C13.351.968.4... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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