Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Optimization of urinary dipstick pH: Are multiple dipstick pH readings reliably comparable to commercial 24-hour urinary pH? | PURPOSE: Accurate measurement of pH is necessary to guide medical management of nephrolithiasis. Urinary dipsticks offer a convenient method to measure pH, but prior studies have only assessed the accuracy of a single, spot dipstick. Given the known diurnal variation in pH, a single dipstick pH is unlikely to reflect t... | ['Adult', 'Aged', 'Circadian Rhythm', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Kidney Calculi', 'Male', 'Middle Aged', 'Nephrolithiasis', 'Prospective Studies', 'Reagent Strips', 'Reproducibility of Results', 'Urinalysis'] | 28,868,511 | [['M01.060.116'], ['M01.060.116.100'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Structured quality report of urologic clinics according to section 137 SGB V. Useful information for the patient, marketing tool of the hospitals, leverage wielded by the health insurance companies, or junk data?]. | In 2005, German hospitals were legally obliged to publish a structured quality report on their data of 2004 including the top 10 diagnosis-related groups, top 10 diagnoses, and top 10 procedures for every specialty. The aim was to increase the transparency for patients, doctors, and health insurance companies. Comparin... | ['Data Collection', 'Diagnosis-Related Groups', 'Germany', 'Humans', 'Insurance, Health', 'International Classification of Diseases', 'Internet', 'Marketing of Health Services', 'National Health Programs', 'Patient Education as Topic', 'Quality Indicators, Health Care', 'Quality of Health Care', 'Reproducibility of Res... | 16,520,915 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N03.219.521.710.305.200.080'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['L01.453.245.945.400'], ['L01.224.230.110.500'], ['J01.219.687.550', 'N03.219.463.548', 'N05.300.430.500'], ['N03.349.550'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Grilled, Barbecued, and Smoked Meat Intake and Survival Following Breast Cancer. | Background: Grilled, barbecued, and smoked meat intake, a prevalent dietary source of polycyclic aromatic hydrocarbon (PAH) carcinogens, may increase the risk of incident breast cancer. However, no studies have examined whether intake of this PAH source influences survival after breast cancer.Methods: We interviewed a ... | ['Aged', 'Animals', 'Breast Neoplasms', 'Cattle', 'Cause of Death', 'Cooking', 'Diet', 'Female', 'Follow-Up Studies', 'Humans', 'Meat', 'Middle Aged', 'New York', 'Polycyclic Aromatic Hydrocarbons', 'Poultry', 'Seafood', 'Sheep', 'Survival Rate', 'Swine'] | 28,052,933 | [['M01.060.116.100'], ['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.500.380.271'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['J01.576.423.200.200'], ['G07.203.650.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[A simple method of extracorporeal membrane oxygenation (ECMO)--2: The effects of ECMO (arterio-venous shunt) on the arterial blood gases measured for 24 hours]. | In eight anesthetized mongrel dogs with thiopental, diazepam and pancuronium bromide, ECMO with arterio-venous shunt was performed under hypoventilation for 24 hours. The blood flow through the ECMO which was connected between the femoral artery and vein was approximately 40% of the cardiac output. Hypoventilation was ... | ['Animals', 'Blood Gas Analysis', 'Dogs', 'Extracorporeal Membrane Oxygenation', 'Time Factors'] | 2,304,251 | [['B01.050'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.880.301', 'E04.292.451'], ['G01.910.857']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development. | The expression of major sarcoplasmic reticulum proteins during cardiac and fast-twitch skeletal muscle development was examined using gene-specific probes. Through the use of S1 nuclease mapping, Northern blot, and RNA slot-blot analysis, sarcoplasmic reticulum proteins were shown to exhibit both narrow tissue specific... | ['Actins', 'Animals', 'Calcium-Binding Proteins', 'Calcium-Transporting ATPases', 'Calsequestrin', 'Cell Line, Transformed', 'Cells, Cultured', 'Female', 'Gene Expression Regulation', 'Heart', 'Isoenzymes', 'Male', 'Mice', 'Muscle Development', 'Muscle Proteins', 'Muscles', 'Myogenin', 'RNA', 'Rabbits', 'Receptors, Cho... | 1,372,478 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D12.776.157.125'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['D12.776.157.125.155', 'D12.776.210.500.220'], ['A11.251.210.172... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphological and gene expression analysis under cool temperature conditions in rice anther development. | Cool temperature conditions are known to lead to pollen sterility in rice. Pollen sterility is an agriculturally important phenomenon because it imparts a large influence directly on rice yield. However, cool temperature stress tolerance varies among rice cultivars and avoidance of cool temperature stress is difficult ... | ['Chromosome Mapping', 'Chromosomes, Plant', 'Fertility', 'Flowers', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Japan', 'Oryza', 'Pollen', 'Quantitative Trait Loci', 'RNA, Messenger', 'RNA, Plant', 'Seeds', 'Temperature', 'Transcription, Genetic'] | 20,558,897 | [['E05.393.183'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['G08.686.210'], ['A18.024.249.500'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['Z01.252.474.463', 'Z01.639.595'], ['B01.650.940.800.575.912.250.822.616'], ['A18.024.249.500.249.500'], ['G05.360.340.024.380.937'], ['D13.444... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Dementia and cognitive impairment in patients with Parkinson's disease from India: a 7-year prospective study. | Depression and cognitive impairment are frequent manifestations in Parkinson's disease (PD). Although a few longitudinal studies have reported on depression and dementia in PD, there is a yet a lack of such studies in India. This 7-year longitudinal study is a hospital-based prospective case (n = 250)-control (n = 280)... | ['Aged', 'Aged, 80 and over', 'Cognitive Dysfunction', 'Dementia', 'Depression', 'Disease Progression', 'Female', 'Humans', 'India', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Parkinson Disease', 'Prospective Studies', 'Risk Factors'] | 24,771,763 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.615.250.700'], ['C10.228.140.380', 'F03.615.400'], ['F01.145.126.350'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.060.116... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Critical considerations for immunocapture enrichment LC-MS bioanalysis of protein therapeutics and biomarkers. | In recent years, immunocapture enrichment coupled with LC-MS technology has seen more applications for the measurement of low abundant protein therapeutics and biomarkers in biological matrices. In this article, several critical considerations for the application of immunocapture enrichment to LC-MS bioanalysis of prot... | ['Biomarkers', 'Chromatography, Liquid', 'Humans', 'Mass Spectrometry', 'Proteins'] | 29,972,311 | [['D23.101'], ['E05.196.181.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D12.776']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An externally fixed femoral fracture model for mice. | Transgenic and knockout mouse models can be used to help understand the molecular mechanisms of fracture repair. This study examines the feasibility of applying an external fixator to the mouse femur as one model for studying fracture repair. The external fixator consisted of two aluminum blocks connected by two rods. ... | ['Animals', 'Behavior, Animal', 'Biomechanical Phenomena', 'Body Weight', 'Bony Callus', 'Disease Models, Animal', 'External Fixators', 'Femoral Fractures', 'Mice', 'Radiography'] | 12,798,069 | [['B01.050'], ['F01.145.113'], ['G01.154.090', 'G01.374.089'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A10.165.265.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['C26.404.061', 'C26.558... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Local food outlets, weight status, and dietary intake: associations in children aged 9-10 years. | BACKGROUND: The rising prevalence of childhood obesity is a key public health issue worldwide. Limited evidence suggests that there may be interactions between environmental factors at a neighborhood level and the development of obesity, with the availability and accessibility of food outlets being potentially importan... | ['Body Mass Index', 'Body Weight', 'Child', 'Commerce', 'Cross-Sectional Studies', 'Diet', 'Diet Records', 'England', 'Female', 'Geographic Information Systems', 'Humans', 'Male', 'Obesity', 'Residence Characteristics', 'Restaurants'] | 21,406,273 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['J01.219'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
Repair of potentially lethal radiation damage in human squamous carcinoma cells after chronic hypoxia. | PURPOSE: To examine the repair of radiation induced potentially lethal damage in A431 and CaSki cells after chronic hypoxia.METHODS AND MATERIALS: Cells in exponential phase are subjected to hypoxia (< 10 ppm oxygen) for up to 12 h and then are allowed to re-oxygenate in air for up to 4 h. Cells are then irradiated wit... | ['Carcinoma, Squamous Cell', 'Cell Hypoxia', 'Cell Survival', 'Humans', 'Radiation Tolerance', 'Tumor Cells, Cultured'] | 8,195,016 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['G03.197.300', 'G04.270.300'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.712', 'G07.738'], ['A11.251.860']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The epidemiology of ankle injuries occurring in English Football Association academies. | OBJECTIVE: To ascertain the epidemiology of ankle injuries in elite youth football.DESIGN: Retrospective analysis of prospectively collected injury data from English Football Association (FA) academies.SETTING: Forty-one FA football academies, between 1998 and 2006.PARTICIPANTS: For the complete seasons studied, a tota... | ['Adolescent', 'Age Distribution', 'Analysis of Variance', 'Ankle Injuries', 'Child', 'England', 'Humans', 'Incidence', 'Prospective Studies', 'Recurrence', 'Referral and Consultation', 'Soccer', 'Time Factors'] | 19,106,152 | [['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C26.558.100'], ['M01.060.406'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A retrospective study of patients with malignant PEComa receiving treatment with sirolimus or temsirolimus: the Royal Marsden Hospital experience. | UNLABELLED: Perivascular epithelioid cell tumors (PEComas) are rare tumors driven by tuberous sclerosis complex gene mutations causing up-regulation of mTOR. We report the outcome of ten consecutive patients treated with sirolimus or temsirolimus.PATIENTS AND METHODS: A retrospective analysis was performed on patients ... | ['Antibiotics, Antineoplastic', 'Antineoplastic Agents', 'Female', 'Humans', 'Male', 'Middle Aged', 'Perivascular Epithelioid Cell Neoplasms', 'Retrospective Studies', 'Sirolimus', 'Treatment Outcome'] | 24,982,384 | [['D27.505.954.248.106'], ['D27.505.954.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.450.692'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clonidine enhances the effects of lidocaine on C-fiber action potential. | We examined local anesthetic effects of clonidine and its interaction with lidocaine with regard to tonic inhibition of the C-fiber action potential (AP) on the isolated, desheathed rabbit vagus nerve by the sucrose gap method. Clonidine and lidocaine at 500 microM concentrations caused a comparable degree of C-fiber i... | ['Action Potentials', 'Animals', 'Clonidine', 'Drug Interactions', 'Lidocaine', 'Membrane Potentials', 'Nerve Fibers', 'Rabbits', 'Tetrodotoxin'] | 1,567,041 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D03.383.129.308.436.500'], ['G07.690.773.968'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.675.542', 'A11.671.501'], ['B01.050.150.900.649.313.968.700'], ['D03.633.100.786.910'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SUMOylation of ATF3 alters its transcriptional activity on regulation of TP53 gene. | Cyclic AMP-dependent transcription factor-3 (ATF3), a stress sensor, plays an essential role in cells to maintain homeostasis and has diverse functions in cellular survival and death signal pathways. ATF3 is a novel regulator of p53 protein stability and function. The activities of ATF3 are modulated by post-translatio... | ['Activating Transcription Factor 3', 'Animals', 'COS Cells', 'Cell Line', 'Chlorocebus aethiops', 'Cysteine Endopeptidases', 'Endopeptidases', 'Genes, p53', 'HEK293 Cells', 'Hep G2 Cells', 'Humans', 'MCF-7 Cells', 'Mutation', 'Neoplasms', 'Protein Inhibitors of Activated STAT', 'Protein Processing, Post-Translational'... | 22,991,139 | [['D12.776.260.108.061.875', 'D12.776.930.127.061.875'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['D08.811.277.656.300'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.02... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer. | A library of sixteen 2nd generation amino- and amido-substituted carboranyl pyrimidine nucleoside analogs, designed as substrates and inhibitors of thymidine kinase 1 (TK1) for potential use in boron neutron capture therapy (BNCT) of cancer, was synthesized and evaluated in enzyme kinetic-, enzyme inhibition-, metabolo... | ['Animals', 'Boron Compounds', 'Boron Neutron Capture Therapy', 'Cell Line, Tumor', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'Glioma', 'Molecular Structure', 'Protein Kinase Inhibitors', 'Pyrimidine Nucleosides', 'Rats', 'Structure-Activity Relationship', 'Thymidine Kinase'] | 26,087,030 | [['B01.050'], ['D01.132', 'D02.203'], ['E02.815.722.500.100'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['G02.111.570', 'G02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electric acupuncture treatment of peripheral nerve injury. | 54 cases of peripheral nerve injury were treated by electric acupuncture and compared with 54 control cases treated with supportive medication. The changes after treatment were observed chiefly by electromyography while sensory and motor improvement were also recorded as auxiliary indicators. The therapeutic results in... | ['Acupuncture Therapy', 'Adolescent', 'Adult', 'Brachial Plexus', 'Child', 'Electroacupuncture', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peroneal Nerve', 'Radial Nerve', 'Wounds and Injuries'] | 7,650,958 | [['E02.190.044'], ['M01.060.057'], ['M01.060.116'], ['A08.800.800.720.050'], ['M01.060.406'], ['E02.186.250', 'E02.190.044.244', 'E02.331.399', 'E02.779.468.399', 'E02.831.535.468.399', 'E03.091.823.500', 'E03.155.519'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.800.800.720.450.760.640... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Perceptions of male partner pressure to be thin and pornography use: Associations with eating disorder symptomatology in a community sample of adult women. | OBJECTIVE: Partner-specific factors have been neglected in eating disorder (ED) research. The present study examined two partner-specific variables that were hypothesized to be linked to women's ED symptoms: perceived male partner thinness-related pressures and pornography use.METHOD: Community women (N = 409) in relat... | ['Body Image', 'Erotica', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Sexual Partners', 'Thinness'] | 30,623,982 | [['F01.752.747.792.110', 'F02.463.593.112'], ['K01.517.414', 'L01.178.682.441'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.778'], ['C23.888.144.828', 'E01.370.600.115.100.160.120.828', 'G07.100.100.160.120.828']] | ['Psychiatry and Psychology [F]', 'Humanities [K]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Complementary encoding of priors in monkey frontoparietal network supports a dual process of decision-making. | Prior expectations of movement instructions can promote preliminary action planning and influence choices. We investigated how action priors affect action-goal encoding in premotor and parietal cortices and if they bias subsequent free choice. Monkeys planned reaches according to visual cues that indicated relative pro... | ['Action Potentials', 'Animals', 'Anticipation, Psychological', 'Choice Behavior', 'Cues', 'Decision Making', 'Electrodes, Implanted', 'Likelihood Functions', 'Macaca mulatta', 'Motor Cortex', 'Motor Neurons', 'Movement', 'Parietal Lobe', 'Pattern Recognition, Visual', 'Psychomotor Performance', 'Reward', 'Stereotaxic ... | 31,612,855 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['F02.463.093'], ['F02.463.785.373.346'], ['F02.463.425.234'], ['F02.463.785.373'], ['E07.305.250.319', 'E07.695.202'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.52... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. | Atopic disease, including atopic dermatitis (eczema), allergy and asthma, has increased in frequency in recent decades and now affects approximately 20% of the population in the developed world. Twin and family studies have shown that predisposition to atopic disease is highly heritable. Although most genetic studies h... | ['Alleles', 'Asthma', 'Child', 'Cohort Studies', 'Dermatitis, Atopic', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Intermediate Filament Proteins', 'Male', 'Mutation', 'Pedigree', 'Skin Physiological Phenomena'] | 16,550,169 | [['G05.360.340.024.340.030'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['C23.550.291.687.500',... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Availability and dose response of phytophenols from a wheat bran rich cereal product in healthy human volunteers. | SCOPE: Phytophenols present in cereals are metabolised to compounds that could be partly responsible for the reduced risk of chronic diseases and all-cause mortality associated with fibre-rich diets. The bioavailability, form and in vivo concentrations of these metabolites require to be established.MATERIALS AND METHOD... | ['Adult', 'Biological Availability', 'Colon', 'Coumaric Acids', 'Dietary Fiber', 'Dose-Response Relationship, Drug', 'Edible Grain', 'Feces', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phenols'] | 27,356,494 | [['M01.060.116'], ['G03.787.151', 'G07.690.725.129'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D02.241.223.200.210'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.690.773.875', 'G07.690.936.500'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The association between childhood irritability and liability to substance use in early adolescence: a 2-year follow-up study of boys at risk for substance abuse. | The aim of this investigation was to determine whether irritability, defined as the propensity to experience and express anger following actual or perceived provocation, is a component of the liability to alcohol and drug abuse. Sons of substance abusing fathers (n = 40) and normal fathers (n = 56) were studied when th... | ['Adolescent', 'Alcoholism', 'Anger', 'Arousal', 'Attention', 'Child', 'Child of Impaired Parents', 'Family', 'Follow-Up Studies', 'Humans', 'Internal-External Control', 'Irritable Mood', 'Male', 'Personality Development', 'Risk Factors', 'Social Environment', 'Substance-Related Disorders'] | 8,556,975 | [['M01.060.057'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.470.093'], ['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['M01.060.406'], ['M01.106'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Tonsillar leiomyosarcoma. | UNLABELLED: Leiomyosarcomas of the head and neck is an extremely rare entity that because of its infrequency has been associated with both delayed diagnosis and misdiagnosis. Sinonasal tract is the most common site in this region. The overall prognosis is poor. It is necessary for appropriate immunohistochemical invest... | ['Actins', 'Adult', 'Delayed Diagnosis', 'Diagnosis, Differential', 'Female', 'Humans', 'Leiomyosarcoma', 'Prognosis', 'Tonsillar Neoplasms'] | 24,220,466 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['M01.060.116'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.455', 'C04.557.450.795.455'], ['E01.789'], ['C04.588.443.665.710.684.800', 'C07.550.745.671.800', 'C09.6... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of the K+ channel Kir7.1 in the developing rat kidney: role in K+ excretion. | BACKGROUND: Coordinated expression of ROMK (luminal K+ channel in the thick ascending limb and the collecting duct) and Na+,K+-ATPase has been demonstrated to be involved in the postnatal development of renal K+ excretion; however, the developmental expression of the basolateral K+ channel Kir7.1 is unknown. The purpos... | ['Animals', 'Animals, Newborn', 'Gene Expression Regulation, Developmental', 'Hyperkalemia', 'Immunohistochemistry', 'Kidney', 'Potassium', 'Potassium Channels', 'Potassium Channels, Inwardly Rectifying', 'RNA, Messenger', 'Rats', 'Sodium-Potassium-Exchanging ATPase'] | 12,631,077 | [['B01.050'], ['B01.050.050.282'], ['G05.308.310'], ['C18.452.950.396'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['A05.810.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Migration of A7 immortalized astrocytic cells grafted into the adult rat striatum. | The A7 cell line is an SV40 large T antigen-immortalized astrocyte cell line produced from the neonatal rat optic nerve. Previous studies have demonstrated that A7 cells provide a favorable environment for the survival and growth of cultured neurons and can also stimulate axonal growth after grafting into the rat stria... | ['Age Factors', 'Animals', 'Astrocytes', 'Bromodeoxyuridine', 'Cell Count', 'Cell Movement', 'Cell Transplantation', 'Male', 'Microinjections', 'Neostriatum', 'Neurites', 'Rats', 'Rats, Sprague-Dawley', 'Transplantation, Heterotopic'] | 8,636,465 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.198', 'G07.568.500.180'], ['E02.095.147.500', 'E04.936.225'], ['E02.319.267... | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
First detection of Baylisascaris procyonis in wild raccoons (Procyon lotor) from Leipzig, Saxony, Eastern Germany. | Baylisascaris procyonis is a zoonotic nematode mainly harbored by the North American raccoon. It can cause severe neurological problems in paratenic hosts and humans. In Germany, raccoons are spread throughout the country. However, the presence of B. procyonis in the German raccoon population has not been thoroughly st... | ['Animals', 'Ascaridida Infections', 'Ascaridoidea', 'Germany', 'Raccoons', 'Zoonoses'] | 29,951,707 | [['B01.050'], ['C01.610.335.508.700.100'], ['B01.050.500.500.294.400.500.100'], ['Z01.542.315'], ['B01.050.150.900.649.313.750.250.623.700'], ['C01.973', 'C22.969']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
A prospective multicenter study of paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure. | BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH), a rare clonal hematopoietic stem cell disorder, is characterized by chronic, uncontrolled complement activation leading to intravascular hemolysis and an inflammatory prothrombotic state. The EXPLORE study aimed to determine the prevalence of undiagnosed PNH in pat... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anemia, Aplastic', 'Bone Marrow', 'Child', 'Clone Cells', 'Female', 'Flow Cytometry', 'Granulocytes', 'Hemoglobinuria, Paroxysmal', 'Hemolysis', 'Humans', 'Immunophenotyping', 'L-Lactate Dehydrogenase', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'Prospectiv... | 24,227,693 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.071.085', 'C15.378.190.223.250'], ['A15.382.216'], ['M01.060.406'], ['A11.251.353'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular differentiation of Mycoplasma gallisepticum and Mycoplasma imitans strains by pulsed-field gel electrophoresis and random amplified polymorphic DNA. | Pulsed-field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD) analysis were used to compare 21 Mycoplasma gallisepticum strains and five M. imitans strains. Each strain of M. gallisepticum typed by PFGE and RAPD methods was genetically quite unique and RAPD and PFGE fingerprinting enabled strain c... | ['Animals', 'Chickens', 'Electrophoresis, Gel, Pulsed-Field', 'Genetic Variation', 'Mycoplasma', 'Mycoplasma Infections', 'Poultry Diseases', 'Random Amplified Polymorphic DNA Technique', 'Reproducibility of Results', 'Turkeys'] | 11,765,805 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.401.220', 'E05.301.300.220'], ['G05.365'], ['B03.440.860.580.553.553'], ['C01.150.252.400.610.610'], ['C22.131.728'], ['E05.393.620.500.687', 'E05.601.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
First metatarsalphalangeal joint arthrodesis: evaluation of plate and screw fixation. | BACKGROUND: First metatarsalphalangeal joint (MTPJ) arthrodesis is a commonly performed procedure for the treatment of a variety of conditions affecting the hallux. There are several different methods to accomplish the fusion. We utilized a method incorporating a ball and cup preparation of the joint, followed by stabi... | ['Arthrodesis', 'Bone Plates', 'Bone Screws', 'Cohort Studies', 'Equipment Failure', 'Female', 'Fracture Healing', 'Humans', 'Joint Diseases', 'Male', 'Metatarsophalangeal Joint', 'Middle Aged', 'Osteotomy', 'Patient Satisfaction', 'Retrospective Studies', 'Treatment Outcome'] | 19,735,631 | [['E04.555.100'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.325'], ['G16.762.891.500'], ['B01.050.150.900.649.313.988.400.112.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synaptic vesicle fusion is modulated through feedback inhibition by dopamine auto-receptors. | Mechanisms of synaptic vesicular fusion and neurotransmitter clearance are highly controlled processes whose finely-tuned regulation is critical for neural function. This modulation has been suggested to involve pre-synaptic auto-receptors; however, their underlying mechanisms of action remain unclear. Previous studies... | ['Animals', 'Animals, Genetically Modified', 'Autoreceptors', 'Caenorhabditis elegans', 'Dopaminergic Neurons', 'Receptors, Dopamine', 'Synapses', 'Synaptic Transmission', 'Synaptic Vesicles'] | 31,494,966 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['D12.776.543.750.035', 'D12.776.543.750.720.670.100'], ['B01.050.500.500.294.400.875.660.250.250'], ['A08.675.278', 'A11.671.270'], ['D12.776.543.750.670.300.400', 'D12.776.543.750.695.150.400', 'D12.776.543.750.720.330.400'], ['A08.850', 'A11.284.149.165.420.780'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical results in severe carpal tunnel syndrome and motor nerve conduction studies. | The purposes of this study were to assess the value of motor nerve conduction studies as a prognostic indicator for severe carpal tunnel syndrome (CTS) and to investigate residual nerve disorder after surgery. Fifty hands in 46 patients with severe CTS were followed for at least 6 months after surgery for open carpal t... | ['Action Potentials', 'Adult', 'Aged', 'Aged, 80 and over', 'Carpal Tunnel Syndrome', 'Chi-Square Distribution', 'Electromyography', 'Female', 'Humans', 'Male', 'Median Nerve', 'Middle Aged', 'Neural Conduction'] | 15,666,118 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E01.370.405.255', 'E01.370.530.255... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Yellow fever immunity surveys in northern Uganda and Kenya and eastern Somalia, 1966-67. | Recent epidemics of yellow fever in eastern Africa have stimulated serological surveys in the Karamoja district of Uganda, the northern frontier district of Kenya and the Giohar district of Somalia. All sera collected in the surveys were screened for group B arbovirus antibody using the HI test. Yellow fever immunity w... | ['Adolescent', 'Adult', 'Antibodies', 'Child', 'Child, Preschool', 'Female', 'Health Surveys', 'Hemagglutination Inhibition Tests', 'Humans', 'Immunoassay', 'Kenya', 'Male', 'Middle Aged', 'Somalia', 'Uganda', 'Yellow Fever'] | 5,302,299 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['E01.370.225.812.735.370', 'E05.200.812.735.370', 'E05.478.594.760.370'], ['B01.050.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effects of age on survival and other parameters in squamous cell carcinoma of the oral cavity, pharynx and larynx. | Many papers have been written on the effect of age on survival from cancer and a number of these papers have concentrated on cancer of the head and neck. The literature is fairly evenly split between those studies that claim that the young patient has a better chance of survival and those that suggest the older patient... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Case-Control Studies', 'Databases, Factual', 'England', 'Female', 'Follow-Up Studies', 'Head and Neck Neoplasms', 'Humans', 'Life Tables', 'Logistic Models', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Proportional Hazards Mode... | 9,563,666 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['Z01.542.363.300'], ['E05.318.372.50... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Organization of butyrate synthetic genes in human colonic bacteria: phylogenetic conservation and horizontal gene transfer. | Butyrate producers constitute an important bacterial group in the human large intestine. Butyryl-CoA is formed from two molecules of acetyl-CoA in a process resembling beta-oxidation in reverse. Three different arrangements of the six genes coding for this pathway have been found in low mol% G+C-content gram-positive h... | ['Acyl Coenzyme A', 'Bacteria, Anaerobic', 'Base Sequence', 'Butyrates', 'Coenzyme A-Transferases', 'Colon', 'Conserved Sequence', 'Gene Transfer, Horizontal', 'Humans', 'Molecular Sequence Data', 'Phylogeny', 'Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Substrate Specificity'] | 17,241,242 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['B03.130'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.241.081.114', 'D10.251.400.143'], ['D08.811.913.817.200'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['G02.111.570.580'], ['G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Structured clinical interview guide for postdeployment psychological screening programs. | Brief structured clinical interviews are a key component of the Department of Defense postdeployment health reassessment program. Such interviews are critical for recommending individuals for follow-up assessment and care. To standardize the interview process, U.S. Army Medical Research Unit-Europe developed a structur... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Interviews as Topic', 'Male', 'Mass Screening', 'Mental Disorders', 'Military Personnel', 'Military Psychiatry', 'Pilot Projects', 'Practice Guidelines as Topic', 'Program Development', 'Psychological Tests', 'Psychometrics', 'Risk Assessment', 'Risk Factors', 'Stress, Psych... | 18,543,560 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Soc... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
'They won't change it back in their heads that we're trash': the intersection of sex work-related stigma and evolving policing strategies. | In Vancouver, Canada, there has been a continuous shift in the policing of sex work away from arresting sex workers, which led to the implementation of a policing strategy that explicitly prioritised the safety of sex workers and continued to target sex workers' clients. We conducted semi-structured interviews with 26 ... | ['Adult', 'Canada', 'Female', 'Humans', 'Male', 'Police', 'Qualitative Research', 'Sex Offenses', 'Sex Work', 'Sex Workers', 'Social Stigma'] | 27,113,456 | [['M01.060.116'], ['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.373.750', 'M01.526.760'], ['H01.770.644.241.850'], ['I01.198.240.748'], ['F01.145.802.790', 'I01.880.735.679'], ['M01.776'], ['F01.145.813.840']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 |
Methadone maintenance and long-term lactation. | Breastfeeding among methadone-maintained women is frequently challenged because of unclear guidelines regarding this practice. Previous research has confirmed that concentrations of methadone in breastmilk in the neonatal period are low. Currently unknown are the concentrations of methadone in breastmilk among women wh... | ['Adult', 'Breast Feeding', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Lactation', 'Male', 'Methadone', 'Milk, Human', 'Postpartum Period', 'Risk Assessment'] | 18,333,767 | [['M01.060.116'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['G08.686.523', 'G08.686.702.500'], ['D02.522.675'], ['A12.200.467', 'A12.790.500', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Effect of Thymosin beta4 on the Differentiation and Mineralization of MC3T3-E1 Cell on a Titanium Surface. | Osteoblasts are responsible for the synthesis of bone matrix through the secretion of collagenous and non-collagenous proteins with mineralization. Thymosin beta4 (Tbeta4) is an actin-sequestering peptide that is involved in the regulation of cell proliferation, differentiation and motility. A recent study reported tha... | ['Animals', 'Antigens, Differentiation', 'Calcification, Physiologic', 'Cell Differentiation', 'Cell Line', 'Dental Implants', 'Gene Expression Regulation', 'Mice', 'Odontoblasts', 'Osteoblasts', 'Surface Properties', 'Thymosin', 'Titanium'] | 27,433,712 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['G04.152'], ['A11.251.210'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['G05.308'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.329.522'], ['A1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness. | Keratins are fibrous proteins. Hair keratins constitute hard structures such as the hair and nails, and cytokeratins have been used as markers of breast carcinoma. However, the expression and function of full-size hair keratin genes have not been previously demonstrated in breast cancer. We investigated the expression ... | ['Breast Neoplasms', 'Cell Line, Tumor', 'Cell Movement', 'Cytoplasm', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Keratins, Hair-Specific', 'Keratins, Type II', 'MCF-7 Cells', 'Mammary Glands, Human', 'Neoplasm Invasiveness', 'Oligonucleotide Array Sequence Analysis'] | 28,405,679 | [['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['A11.284.430.214'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450.149', 'D12.776.220.475.450.149', 'D12.776.860.607.149'], ['D05.750.078.593.450.600', 'D12.776.220.475.... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of optimally resected hepatectomy and peritonectomy patients with colorectal cancer metastasis. | BACKGROUND: Hepatectomy is the standard of care for patients with colorectal liver metastases (CRLM) but cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC) are still not widely accepted as the definitive treatment for patients with peritoneal carcinomatosis of colorectal origin (CRPC). We ... | ['Chemotherapy, Cancer, Regional Perfusion', 'Colorectal Neoplasms', 'Female', 'Hepatectomy', 'Humans', 'Hyperthermia, Induced', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Peritoneal Neoplasms', 'Peritoneum', 'Prospective Studies', 'Survival Analysis'] | 19,697,395 | [['E02.319.267.200', 'E04.292.425'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional outcome and quality of life after traumatic total brachial plexus injury treated by nerve transfer or single/double free muscle transfers: a comparative study. | AIMS: Between 2002 and 2011, 81 patients with a traumatic total brachial plexus injury underwent reconstruction by double free muscle transfer (DFMT, 47 cases), single muscle transfer (SMT, 16 cases) or nerve transfers (NT, 18 cases).METHODS: They were evaluated for functional outcome and quality of life (QoL) using th... | ['Adolescent', 'Adult', 'Brachial Plexus', 'Brachial Plexus Neuropathies', 'Elbow Joint', 'Female', 'Follow-Up Studies', 'Hand Strength', 'Humans', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Nerve Transfer', 'Postoperative Care', 'Preoperative Care', 'Quality of Life', 'Range of Motion, Articular', 'Recovery of Functi... | 26,850,426 | [['M01.060.057'], ['M01.060.116'], ['A08.800.800.720.050'], ['C10.668.829.100'], ['A02.835.583.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Rural Family Medicine Outcomes at the University of Minnesota Medical School Duluth. | BACKGROUND AND OBJECTIVES: The University of Minnesota Medical School Duluth (MSD) opened in 1972 with a mission to train physicians serving rural Minnesota, emphasizing family medicine and American Indian (AI) communities. Nationwide there are shortages in family medicine and AI physicians, and MSD is a leader in thes... | ['Adult', 'Career Choice', 'Education, Medical, Graduate', 'Family Practice', 'Female', 'Humans', 'Indians, North American', 'Longitudinal Studies', 'Male', 'Medically Underserved Area', 'Minnesota', 'Physicians, Family', 'Professional Practice Location', 'Retrospective Studies', 'Rural Health Services', 'Workforce'] | 28,535,321 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['I02.358.337.350', 'I02.358.399.350'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['N03.349.650.340', 'N05.300.450.520'], ['Z01.1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Interferon beta-1b is effective in Japanese RRMS patients: a randomized, multicenter study. | OBJECTIVE: To assess the efficacy of interferon beta-1b (IFNB-1b) in Japanese patients with relapsing-remitting multiple sclerosis (RRMS).BACKGROUND: The effects of IFNB in RRMS have been assessed in study populations comprised predominantly of white patients. MS in Japanese patients is different from that in white pat... | ['Adolescent', 'Adult', 'Brain', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Fever', 'Humans', 'Immunologic Factors', 'Interferon beta-1b', 'Interferon-beta', 'Japan', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multiple Sclerosis, Relapsing-Remitting', 'Optic Nerve', 'Recurrence', '... | 15,728,282 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477'], ['D12.644.276.374.440.890.275.750', 'D12.776.467.37... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characteristics of early filtering blebs that predict successful trabeculectomy identified via three-dimensional anterior segment optical coherence tomography. | BACKGROUND/AIMS: To identify the cross-sectional characteristics of filtering blebs at 2 weeks post-trabeculectomy associated with intraocular pressure (IOP) control at 1 year post-trabeculectomy.METHODS: Ninety-nine eyes of 94 patients who had undergone primary trabeculectomy were included in this retrospective consec... | ['Aged', 'Diagnostic Techniques, Ophthalmological', 'Female', 'Filtering Surgery', 'Glaucoma', 'Humans', 'Imaging, Three-Dimensional', 'Intraocular Pressure', 'Logistic Models', 'Male', 'Middle Aged', 'Retrospective Studies', 'Tomography, Optical Coherence', 'Trabeculectomy'] | 28,893,760 | [['M01.060.116.100'], ['E01.370.380'], ['E04.540.450'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['G14.440'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Proteome of the rete testis fluid from tropically-adapted Morada Nova rams. | The rete testis has a close relationship with sperm development and may have other functions besides serving as an intercalated channel. The aim of this study was to identify and characterize the proteins of rete testis fluid (RTF) from tropically-adapted Morada Nova rams. Testicles obtained from six Morada Nova rams w... | ['Adaptation, Physiological', 'Animals', 'Body Fluids', 'Gene Expression Regulation', 'Male', 'Proteome', 'Rete Testis', 'Sheep', 'Tropical Climate'] | 27,908,670 | [['G07.025', 'G16.012.500'], ['B01.050'], ['A12.207'], ['G05.308'], ['D12.776.817'], ['A05.360.444.849.600'], ['B01.050.150.900.649.313.500.380.791'], ['G16.500.275.071.600', 'N06.230.300.100.250.600']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Allotetraploid cryptic species in Asplenium normale in the Japanese Archipelago, detected by chemotaxonomic and multi-locus genotype approaches. | PREMISE OF THE STUDY: Delimitation of cryptic species provides an understanding of biodiversity and opportunities to elucidate speciation processes. Extensive flavonoid variation has been reported in the tetraploid cytotype of the fern, Asplenium normale, although related species have no intraspecific variations in fla... | ['DNA, Chloroplast', 'Ferns', 'Flavonoids', 'Genetic Speciation', 'Phylogeny', 'Tetraploidy'] | 29,885,241 | [['D13.444.308.283.170', 'D13.444.308.435.275'], ['B01.650.940.800.575.912.063'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G05.045.350', 'G16.075.350'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['C23.550.210.702.249', 'G05.365.590.175.677.249', 'G05.700.740.249']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Differential neural activity and connectivity for processing one's own face: a preliminary report. | The experience of self is unique and pivotal to clinically relevant cognitive and emotional functions. However, well-controlled data on specialized brain regions and functional networks underlying the experience of self remain limited. This functional magnetic resonance imaging study investigated neural activity and co... | ['Adult', 'Brain Mapping', 'Cerebral Cortex', 'Face', 'Female', 'Functional Laterality', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Neural Pathways', 'Oxygen', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Psychological Tests', 'Reaction Time', 'Self Concept', 'Statistics as... | 21,962,775 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['A01.456.505'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['A08.612'], ['D01.268.185.550', 'D01.362.670'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Early life seizures in female rats lead to anxiety-related behavior and abnormal social behavior characterized by reduced motivation to novelty and deficit in social discrimination. | Previously, we demonstrated that male Wistar rats submitted to neonatal status epilepticus showed abnormal social behavior characterized by deficit in social discrimination and enhanced emotionality. Taking into account that early insult can produce different biological manifestations in a gender-dependent manner, we a... | ['Age Factors', 'Analysis of Variance', 'Animals', 'Animals, Newborn', 'Anxiety', 'Exploratory Behavior', 'Female', 'Maze Learning', 'Motivation', 'Rats', 'Rats, Wistar', 'Seizures', 'Social Behavior Disorders', 'Social Discrimination'] | 25,139,483 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.050.282'], ['F01.470.132'], ['F01.145.387', 'F01.658.370'], ['F02.463.425.874.500'], ['F01.658', 'F01.752.543.500.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.3... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Antibiotic residue prevention methods, farm management, and occurrence of antibiotic residues in milk. | The objective of this study was to determine associations among the occurrence of antibiotic residues in bulk milk and various farm management practices. Ninety-four dairy farms were visited after antibiotic residues were detected in samples of their bulk milk (case farms) along with an equal number of residue-free far... | ['Animals', 'Anti-Bacterial Agents', 'Cattle', 'Cattle Diseases', 'Dairying', 'Drug Residues', 'Female', 'Milk', 'Regression Analysis', 'Surveys and Questionnaires'] | 1,894,808 | [['B01.050'], ['D27.505.954.122.085'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['J01.040.246'], ['N06.850.460.200.250'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.308.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Glutamate presynaptic vesicular transporter and postsynaptic receptor levels correlate with spatial memory status in aging rat models. | In humans, memory capacities are generally affected with aging, even without any reported neurologic disorders. The mechanisms behind cognitive decline are not well understood. We studied here whether postsynaptic glutamate receptor and presynaptic vesicular glutamate transporters (VGLUTs) levels may change in the cour... | ['Aging', 'Animals', 'Biomarkers', 'Cerebral Cortex', 'Cognition Disorders', 'Female', 'Gene Expression', 'Hippocampus', 'Male', 'Models, Animal', 'Rats, Inbred Strains', 'Rats, Long-Evans', 'Receptors, AMPA', 'Receptors, N-Methyl-D-Aspartate', 'Spatial Memory', 'Vesicular Glutamate Transport Protein 1', 'Vesicular Glu... | 25,556,161 | [['G07.345.124'], ['B01.050'], ['D23.101'], ['A08.186.211.200.885.287.500'], ['F03.615.250'], ['G05.297'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E05.598'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['D12.776.157.5... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Facial paralysis induced by herpes simplex virus type 1 and the study of facial neurons apoptosis in mice]. | OBJECTIVE: To study the apoptosis of facial motor neurons and the expression of apoptosis-related genes, Bcl-2 and Bax, in the animal model of viral facial paralysis.METHODS: Total of 84 Balb/c mice were divided into viral inoculation group and nerve transaction group. The animals were executed 1, 3, 7, 10, 15, 20 and ... | ['Animals', 'Apoptosis', 'Facial Paralysis', 'Female', 'Herpesvirus 1, Human', 'Mice', 'Mice, Inbred BALB C', 'Neurons', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-bcl-2', 'bcl-2-Associated X Protein'] | 22,177,043 | [['B01.050'], ['G04.146.954.035'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.636.214'], ['B04.280.382.100.750.390'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['A08.675', 'A11.671'], ['D12.776.624.664.700'], ['D12.644.360.075.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of shear stress in the flow through the sampling needle on concentration of nanovesicles isolated from blood. | During harvesting of nanovesicles (NVs) from blood, blood cells and other particles in blood are exposed to mechanical forces which may cause activation of platelets, changes of membrane properties, cell deformation and shedding of membrane fragments. We report on the effect of shear forces imposed upon blood samples d... | ['Adult', 'Erythrocytes', 'Extracellular Vesicles', 'Female', 'Flow Cytometry', 'Humans', 'Male', 'Microscopy, Electron, Scanning', 'Middle Aged', 'Nanostructures', 'Needles', 'Platelet-Rich Plasma', 'Stress, Mechanical', 'Young Adult'] | 27,737,793 | [['M01.060.116'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.284.295.588'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The mutagenic properties of BrdUTP in a random mutagenesis process. | To explore the mutagenic properties of the nucleotide analogue bromodeoxyuridine triphosphate (BrdUTP), the wild type alpha-amylase (xamy) gene from Xanthomonas campestris pv. campestris 8004 was used as a mutational target. It was mutated using PCR techniques to partially replace deoxythymidine triphosphate (dTTP) wit... | ['Base Pair Mismatch', 'DNA, Bacterial', 'Deoxyuracil Nucleotides', 'Mutagenesis', 'Mutation', 'Polymerase Chain Reaction', 'Thymine Nucleotides', 'Xanthomonas campestris', 'alpha-Amylases'] | 17,874,205 | [['G05.365.590.060'], ['D13.444.308.212'], ['D03.383.742.686.850.210', 'D13.695.201.200', 'D13.695.740.850.210'], ['G05.558'], ['G05.365.590'], ['E05.393.620.500'], ['D03.383.742.686.706', 'D13.695.201.789', 'D13.695.740.706'], ['B03.440.400.425.967.930.100', 'B03.660.250.915.930.100'], ['D08.811.277.450.066.050']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of reading with reversed speech on frequency of stuttering in adults. | This study explored the effect of reading with reversed speech on the frequency of stuttering. Eight adults who stutter served as participants and read four 300-syllable passages while listening to three types of speech stimuli: normal speech (choral reading), reversed speech at normal speed, reversed speech at half sp... | ['Acoustic Stimulation', 'Adult', 'Feedback', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reading', 'Speech Perception', 'Speech Therapy', 'Stuttering', 'Tape Recording'] | 15,974,349 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.559.423.557'], ['F02.463.593.071.875', 'G07.888.125.875'], ['E02.760.169.063.500.727.552', 'E02.831.727.552'], ['C10.597.606.150.500.800.750', 'C23.888.592.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Poverty, environment, and health: the role of environmental epidemiology and environmental epidemiologists. | International attention is focusing increasingly on environmental concerns, from global warming and extreme weather to persistent chemical pollutants that affect our food supplies, health and well-being. These environmental exposures disproportionately affect the poor and those residing in developing countries, and may... | ['Environmental Exposure', 'Environmental Health', 'Epidemiology', 'Global Health', 'Humans', 'Poverty', 'Public Health'] | 18,049,181 | [['N06.850.460.350'], ['H02.229'], ['H02.403.720.500'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['H02.403.720', 'N01.400.550', 'N06.850']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Machine preservation of 450 cadaver kidneys. | Cadaver kidneys procured from homeostatic donors can be preserved for periods up to 67 hours without adversely affecting graft survival. Donor creatinine, use of vasopressors, and perfusion characteristics do not seem important factors. | ['Adolescent', 'Adult', 'Brain Death', 'Cadaver', 'Child', 'Child, Preschool', 'Follow-Up Studies', 'Graft Survival', 'Humans', 'Infant', 'Kidney', 'Kidney Transplantation', 'Middle Aged', 'Organ Preservation', 'Tissue Donors', 'Tissue Preservation', 'Transplantation, Homologous'] | 7,017,687 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140.151', 'C10.597.606.358.800.200.100', 'C23.550.260.159'], ['C23.550.260.224'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The need for neuroprotective therapies in Parkinson's disease: a clinical perspective. | Slowing of disease progression remains a major unmet need in the treatment of Parkinson's disease (PD). Multiple factors are responsible for progression of disability in this disorder including worsening of cardinal motor features due to progressive nigral pathology, the evolution of poorly levodopa-responsive symptoms... | ['Clinical Trials as Topic', 'Cognition Disorders', 'Neuroprotective Agents', 'Parkinson Disease', 'Practice Guidelines as Topic', "Practice Patterns, Physicians'"] | 16,717,249 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F03.615.250'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['N04.761.700.350.650', 'N05.700.350.650'], ['N04.590.374.577', 'N05.300.625']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vitreous concentration of topically applied brimonidine-purite 0.15%. | PURPOSE: The aim of this study was to determine the vitreous brimonidine concentration of topically applied brimonidine-Purite 0.15%.METHODS: Patients scheduled for a pars plana vitrectomy were invited to participate in this study after institutional review board (IRB) approval was obtained. Each patient was asked to a... | ['Administration, Topical', 'Adrenergic alpha-Agonists', 'Aged', 'Antihypertensive Agents', 'Biological Availability', 'Brimonidine Tartrate', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Male', 'Ophthalmic Solutions', 'Quinoxalines', 'Tissue Distribution', 'Vitrectomy', 'Vitreous Body'] | 16,910,864 | [['E02.319.267.120'], ['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['M01.060.116.100'], ['D27.505.954.411.162'], ['G03.787.151', 'G07.690.725.129'], ['D03.633.100.857.070'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.776.708.645', 'D27.505.954.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action. | Essential cell division protein FtsZ is considered an attractive target in the search for antibacterials with novel mechanisms of action to overcome the resistance problem. FtsZ undergoes GTP-dependent assembly at midcell to form the Z-ring, a dynamic structure that evolves until final constriction of the cell. Therefo... | ['Anti-Bacterial Agents', 'Bacillus subtilis', 'Bacterial Proteins', 'Binding Sites', 'Biphenyl Compounds', 'Cytoskeletal Proteins', 'Guanosine Triphosphate', 'Kinetics', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Models, Molecular', 'Naphthalenes', 'Protein Binding', 'Protein Struct... | 25,486,266 | [['D27.505.954.122.085'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['G02.111.570.120'], ['D02.455.426.559.389.185'], ['D12.776.220'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', 'D13.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the FXG™: RESP (Asp+) real-time PCR assay with direct immunofluorescence and calcofluor white staining for the detection of Pneumocystis jirovecii in respiratory specimens. | We compared the FXG™: RESP (Asp +) real-time PCR assay (Myconostica Ltd) with two microscopic staining methods (direct immunofluorescence [IFA] and calcofluor white) for the detection of Pneumocystis jirovecii in 411 respiratory specimens submitted for P. jirovecii examination. We considered the specimen to be microsco... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Benzenesulfonates', 'Child', 'Child, Preschool', 'Female', 'Fluorescent Antibody Technique, Direct', 'Humans', 'Infant', 'Male', 'Microbiological Techniques', 'Microscopy', 'Middle Aged', 'Mycology', 'Pneumocystis carinii', 'Pneumonia, Pneumocystis', 'Real-Time Poly... | 21,859,386 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.240.300', 'E05.200.500.607.512.240.300', 'E05.200.750.551.512.240.300', 'E05.478... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacokinetics of YK754, a novel If channel inhibitor in rats, dogs and humans. | The pharmacokinetics of YM758, a novel funny If current channel (If channel) inhibitor, was investigated after single intravenous (i.v.) and oral dosing to rats and dogs, and partially compared with the results in humans by using liver microsomes. After i.v. administration, the plasma YM758 concentrations decreased, wi... | ['Administration, Oral', 'Animals', 'Area Under Curve', 'Blood Cells', 'Blood Proteins', 'Cyclic Nucleotide-Gated Cation Channels', 'Dogs', 'Humans', 'Injections, Intravenous', 'Male', 'Microsomes, Liver', 'Protein Binding', 'Rats', 'Rats, Inbred F344', 'Tetrahydroisoquinolines'] | 18,777,947 | [['E02.319.267.100'], ['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['A11.118', 'A15.145.229'], ['D12.776.124'], ['D12.776.157.530.400.337', 'D12.776.543.550.450.452', 'D12.776.543.585.400.452'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement. | To divide in a tissue, both normal and cancer cells become spherical and mechanically stiffen as they enter mitosis. We investigated the effect of oncogene activation on this process in normal epithelial cells. We found that short-term induction of oncogenic RasV12 activates downstream mitogen-activated protein kinase ... | ['Cell Line', 'Cell Shape', 'Chromosome Segregation', 'Humans', 'MAP Kinase Signaling System', 'Mitosis', 'Spindle Apparatus', 'Stress, Mechanical', 'ras Proteins'] | 32,032,547 | [['A11.251.210'], ['G04.320'], ['G04.144.220.220.625', 'G05.113.220.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['G04.144.220.220.781', 'G05.113.220.781'], ['A11.284.430.214.190.750.820'], ['G01.374.835'], ['D08.811.277.040.330.300.400.500', 'D12.644.360.52... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumor resection utilizing a minimally invasive spinal retractor with a novel cranial adaptor. | OBJECTIVE: This article describes a method of performing an intracerebral tumor resection utilizing a novel dilator attachment with a system designed for minimally invasive spinal surgery.METHODS: A novel dilator was designed and utilized in conjunction with a retractor system originally designed for minimally invasive... | ['Aged', 'Aged, 80 and over', 'Brain Neoplasms', 'Female', 'Glioma', 'Humans', 'Male', 'Minimally Invasive Surgical Procedures', 'Neurosurgical Procedures', 'Treatment Outcome'] | 19,061,149 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.502'], ['E04.525'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Revealing the conceptual substrate of biomedical cognitive models to the wider community. | The patient authoring interface for each disease in the Maryland Virtual Patient simulation environment reveals the conceptual substrate of the disease model. Revealing the disease model to the community both explains how the interactive simulations work and invites collaboration from the wider community. | ['Cognition', 'Computer Simulation', 'Computer-Assisted Instruction', 'Cooperative Behavior', 'Education, Medical', 'Esophageal Diseases', 'Humans', 'Maryland', 'Patient Simulation', 'User-Computer Interface'] | 18,391,305 | [['F02.463.188'], ['L01.224.160'], ['I02.903.771.500.208'], ['F01.145.813.115'], ['I02.358.399'], ['C06.405.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['I02.903.847.500'], ['L01.224.900.910']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
Symptom clusters in men and women with heart failure and their impact on cardiac event-free survival. | BACKGROUND: Because patients with heart failure (HF) experience multiple symptoms simultaneously, it is necessary to explore symptom clusters rather than individual symptoms to determine their impact on outcomes. Given gender differences in symptom experience, examination of potential gender differences in clusters is ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Cluster Analysis', 'Cognition Disorders', 'Disease-Free Survival', 'Dyspnea', 'Fatigue', 'Female', 'Georgia', 'Heart Failure', 'Humans', 'Indiana', 'Kentucky', 'Male', 'Men', 'Middle Aged', 'Proportional Hazards Models', 'Prospective Studies', 'Severity... | 20,539,161 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['F03.615.250'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Somatostatin release and plasma molecular somatostatin components in man. | The present paper describes a sensitive, precise and specific radioimmunoassay method for measurements of plasma somatostatin; significant rises in plasma somatostatin following a test meal, intraduodenal infusion of fat and HCl, and intravenous injection of insulin; and separation of immunoreactive plasma somatostatin... | ['Adult', 'Corn Oil', 'Food', 'Growth Hormone-Releasing Hormone', 'Humans', 'Hydrochloric Acid', 'Insulin', 'Male', 'Oils', 'Radioimmunoassay', 'Secretory Rate'] | 6,433,648 | [['M01.060.116'], ['D10.212.302.380.370', 'D10.212.507.340', 'D10.627.700.240', 'D20.215.784.750.240', 'G07.203.300.375.400.250', 'J02.500.375.400.250'], ['G07.203.300', 'J02.500'], ['D06.472.699.327.740.860', 'D12.644.400.400.740.860', 'D12.644.548.365.740.860', 'D12.776.631.650.405.740.860'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
[Internal control of working conditions as a form of occupational health and safety management--experience of Western European countries and the situation in Poland]. | Good occupational health and safety management not only protects workers from hazards and health impairment, but also contributes to the success of the enterprise as a whole. The internal control of working conditions in an enterprise, carried out by an employer, is one of the forms of occupational health and safety ma... | ['Employment', 'Europe', 'Occupational Health', 'Poland', 'Program Development', 'Safety Management'] | 11,288,694 | [['N01.824.245'], ['Z01.542'], ['N01.400.525'], ['Z01.542.248.679'], ['N04.452.760'], ['N04.452.871.900', 'N06.850.135.060.075.800']] | ['Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Arabidopsis plants exposed to dioxin result in a WRINKLED seed phenotype due to 20S proteasomal degradation of WRI1. | Dioxins are highly toxic persistent organic pollutants bioaccumulated by both plants and animals that cause severe developmental abnormalities in humans. We investigated the effects of dioxins on seed development in Arabidopsis. Plants were exposed to various concentrations of the most toxic congener of dioxins, 2,3,7,... | ['Arabidopsis', 'Arabidopsis Proteins', 'Environmental Pollutants', 'Phenotype', 'Polychlorinated Dibenzodioxins', 'Proteasome Endopeptidase Complex', 'Seeds', 'Transcription Factors'] | 29,394,403 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D27.888.284'], ['G05.695'], ['D02.309.500.450', 'D03.633.300.786'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D12.776.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Retention of a functional resact receptor in isolated sperm plasma membranes. | Resact, a peptide obtained from eggs, causes a change in the Mr, and a loss of 32P from a plasma membrane protein identified as guanylate cyclase. Here, a resact analog (125I-[Tyr1, Ser8] resact) was synthesized and shown to bind to isolated sperm membranes. Resact, but not speract, competed with the radiolabeled ligan... | ['Animals', 'Binding, Competitive', 'Cell Membrane', 'Chemotaxis', 'Cyclic GMP', 'Egg Proteins', 'Guanylate Cyclase', 'Male', 'Membrane Proteins', 'Molecular Weight', 'Oligopeptides', 'Peptides', 'Phosphorylation', 'Receptors, Cell Surface', 'Sea Urchins', 'Spermatozoa'] | 2,870,813 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.284.149'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D12.776.290'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient neuroplasticity induction in chronic stroke patients by an associative brain-computer interface. | Brain-computer interfaces (BCIs) have the potential to improve functionality in chronic stoke patients when applied over a large number of sessions. Here we evaluated the effect and the underlying mechanisms of three BCI training sessions in a double-blind sham-controlled design. The applied BCI is based on Hebbian pri... | ['Adult', 'Aged', 'Association', 'Brain-Computer Interfaces', 'Evoked Potentials, Motor', 'Female', 'Foot', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Neuronal Plasticity', 'Pyramidal Tracts', 'Recovery of Function', 'Stroke', 'Stroke Rehabilitation'] | 26,719,088 | [['M01.060.116'], ['M01.060.116.100'], ['F02.463.425.069', 'F04.754.720.346'], ['E07.305.076'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['A01.378.610.250'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['G11.561.638'], ['A08.186.8... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
abiliti Closed-Loop Gastric Electrical Stimulation System for Treatment of Obesity: Clinical Results with a 27-Month Follow-Up. | BACKGROUND: The aim of the study was to evaluate the safety and effectiveness of a novel closed-loop gastric electric stimulation device (abiliti system) featuring a transgastric sensor to detect food intake and an accelerometer to record physical activity to induce and maintain lifestyle changes to treat obesity.METHO... | ['Adult', 'Electric Stimulation Therapy', 'Electrodes, Implanted', 'Exercise', 'Feeding Behavior', 'Female', 'Follow-Up Studies', 'Humans', 'Hunger', 'Life Style', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Prostheses and Implants', 'Quality of Life', 'Stomach', 'Surveys and Questionnaires', 'Treatment Outcome', 'Weigh... | 25,771,794 | [['M01.060.116'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Exploration of sustainable development by applying green economy indicators. | Following the global trend of sustainable development, development of green economy is the best way of slowing the negative ecological and environmental impact. This research establishes the Taiwan's green economic indicators based on the ecological footprint and energy analysis. The results are as follows: Taiwan's ec... | ['Carbon Footprint', 'Conservation of Natural Resources', 'Energy-Generating Resources', 'Environmental Monitoring', 'Models, Statistical', 'Taiwan'] | 21,336,490 | [['G16.500.275.066', 'N06.230.063'], ['J01.256', 'N06.230.080'], ['N06.230.132'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['Z01.252.474.872', 'Z01.639.850']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[Violent patients in a psychiatric outpatient department]. | During the period 23.11.1987-22.11.1989, a total of 7,906 patients attended the psychiatric outpatient department and observation section on 12,469 occasions. Sixty patients (0.8%) behaved violently on 85 occasions. None of these episodes of violence resulted in injuries to persons requiring medical attention. 90% of t... | ['Adolescent', 'Adult', 'Denmark', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Outpatients', 'Psychiatric Department, Hospital', 'Violence'] | 1,926,614 | [['M01.060.057'], ['M01.060.116'], ['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['M01.643.630'], ['N02.278.216.500.968.641', 'N04.452.442.452.422.641'], ['I01.198.240.856', 'I01.880.735.900']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Computational models of cells and tissues: machines, agents and fungal infection. | Computational models have been of interest in biology for many years and have represented a particular approach to trying to understand biological processes and phenomena from a systems point of view. Much of the early work was rather abstract and high level and probably seemed to many to be of more philosophical than ... | ['Computational Biology', 'Computer Simulation', 'Magnaporthe', 'Models, Biological', 'Mycology', 'Oryza', 'Plant Diseases'] | 11,589,587 | [['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['B01.300.107.575'], ['E05.599.395'], ['H01.158.273.540.553'], ['B01.650.940.800.575.912.250.822.616'], ['G15.610']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Family-to-family: a trauma-and-recovery model of family education. | A peer educational program sponsored by the National Alliance for the Mentally Ill uses a unique combination of healing, consciousness-raising, and empowerment to serve long-neglected family needs. | ['Family', 'Health Education', 'Humans', 'Mental Disorders', 'Models, Psychological', 'Self-Help Groups', 'United States', 'Voluntary Health Agencies'] | 9,610,145 | [['F01.829.263', 'I01.880.853.150'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['E05.599.695'], ['N03.540.782'], ['Z01.107.567.875'], ['N03.540.630.780']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Problems encountered with longitudinal neurological, psychometric and cerebral CT imaging among stroke data bank patients with dementia. | 41 patients (30 men, 11 women, mean age 65.3 +/- 9.7 years) with probable ischemic vascular dementia diagnosed according to stated clinical criteria at least 3 months after hospital discharge and among a few nonhospitalized subjects with thorough clinical, neurovascular and neuroimaging workup have been followed for th... | ['Aged', 'Brain', 'Databases, Factual', 'Dementia, Vascular', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Neurologic Examination', 'Neuropsychological Tests', 'Psychometrics', 'Regional Blood Flow', 'Survival Rate', 'Tomography, X-Ray Computed'] | 7,800,115 | [['M01.060.116.100'], ['A08.186.211'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C10.228.140.300.400', 'C10.228.140.300.510.800.500', 'C10.228.140.380.230', 'C10.228.140.695.500', 'C14.907.137.126.372.500', 'C14.907.253.560.350.500', 'F03.615.400.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.3... | ['Named Groups [M]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The effect of amino-acid infusion during off-pump coronary arterial bypass surgery on thermogenic and hormonal regulation. | PURPOSE: Amino-acid (AA) infusions promote thermogenesis and prevent perioperative hypothermia, but the mechanism of action is unknown. We sought to verify the hypothesis that AA infusions stimulate the release of metabolic hormones during surgery and increase energy expenditure, resulting in thermogenesis.METHODS: Twe... | ['Aged', 'Amino Acids', 'Anesthesia, General', 'Blood Glucose', 'Blood Urea Nitrogen', 'Body Temperature Regulation', 'Coronary Artery Bypass, Off-Pump', 'Epinephrine', 'Female', 'Hemodynamics', 'Hormones', 'Humans', 'Hypothermia', 'Infusions, Intravenous', 'Insulin', 'Intraoperative Complications', 'Leptin', 'Male', '... | 19,011,772 | [['M01.060.116.100'], ['D12.125'], ['E03.155.197'], ['D09.947.875.359.448.500'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['D02.033.100.291.310', 'D02.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sedation for paediatric transcatheter atrial septal defect closure: comparison of two sedation protocols. | AIM: This study aimed to compare the effects of dexmedetomidine-propofol and ketamine-propofol sedation on haemodynamic stability, immobility, and recovery time in children who underwent transcatheter closure of atrial septal defects.METHODS: In all, 46 children scheduled for transcatheter closure of atrial septal defe... | ['Adolescent', 'Anesthesia, Intravenous', 'Anesthetics, Intravenous', 'Cardiac Catheterization', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Dexmedetomidine', 'Female', 'Heart Septal Defects, Atrial', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Propofol', 'Treatment Outcome'] | 24,018,106 | [['M01.060.057'], ['E03.155.308'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['D03.383.129.308.245'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acetylcholinesterase and heat shock protein 70 response in larval brain tissue of Lymantria dispar L. (Lepidoptera, Limantriidae) upon chronic exposure to benzo(a)pyrene. | The effects of different concentrations of benzo(a)pyrene (BaP) (2, 10, 20, 100, 200, and 2000 ng/g dry food weight) on the activity of acetylcholinesterase (AChE) and concentration of heat-shock protein 70 (hsp70) in fifth instar Lymantria dispar brain tissue were investigated. Inhibition of AChE is a general effect b... | ['Acetylcholinesterase', 'Animals', 'Benzo(a)pyrene', 'Carcinogens', 'Dose-Response Relationship, Drug', 'Environmental Biomarkers', 'Environmental Pollutants', 'HSP70 Heat-Shock Proteins', 'Insect Proteins', 'Larva', 'Moths', 'Mutagens'] | 28,795,330 | [['D08.811.277.352.100.170.176'], ['B01.050'], ['D02.455.426.559.847.799.306.300', 'D04.615.799.306.300'], ['D27.888.569.100'], ['G07.690.773.875', 'G07.690.936.500'], ['D23.101.258', 'G16.505', 'N06.850.460.350.080.250'], ['D27.888.284'], ['D12.776.580.216.375'], ['D12.776.093.500'], ['B05.500.500', 'G07.345.500.550.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Failure of a dietary model to affect markers of inflammation in domestic cats. | BACKGROUND: Oxidative stress and inflammation can be altered by dietary factors in various species. However, little data are available in true carnivorous species such as domestic cats. As numerous anti-inflammatory and anti-oxidative additives become available and might be of use in cats with chronic low-grade inflamm... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Biomarkers', 'Cats', 'Cytokines', 'Diet', 'Dietary Fats', 'Fatty Acids, Omega-6', 'Female', 'Gene Expression Regulation', 'Inflammation', 'Male', 'Oxidative Stress'] | 24,885,092 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['D23.101'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D10.251.355.343'], ['G05.308'], ['C23.550.470'], [... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Texture characterization for joint compression and classification based on human perception in the wavelet domain. | Today's multimedia applications demand sophisticated compression and classification techniques in order to store, transmit, and retrieve audio-visual information efficiently. Over the last decade, perceptually based image compression methods have been gaining importance. These methods take into account the abilities (a... | ['Algorithms', 'Artificial Intelligence', 'Biomimetics', 'Cluster Analysis', 'Data Compression', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Visual Perception'] | 16,764,265 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['H01.158.550.100', 'J01.897.120.100'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.308.189', 'L01.224.800.500', 'L01.470.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Oxidative stress markers imbalance in late-life depression. | BACKGROUND: Oxidative stress has been implicated in the pathophysiology of mood disorders in young adults. However, there is few data to support its role in the elderly. The primary aim of this study was to evaluate whether subjects with late-life depression (LLD) presented with changes in oxidative stress response in ... | ['Aged', 'Aged, 80 and over', 'Cognition Disorders', 'Depression', 'F2-Isoprostanes', 'Female', 'Glutathione Peroxidase', 'Glutathione Reductase', 'Glutathione Transferase', 'Humans', 'Lipid Peroxidation', 'Male', 'Middle Aged', 'Oxidative Stress', 'Protein Carbonylation', 'Thiobarbituric Acid Reactive Substances'] | 29,574,402 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.615.250'], ['F01.145.126.350'], ['D10.251.355.255.100.375.500', 'D10.251.355.310.166.775.500', 'D10.251.355.411.500'], ['D08.811.682.732.500'], ['D08.811.682.667.092'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.515', 'G03.295... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Floral symmetry: pollinator-mediated stabilizing selection on flower size in bilateral species. | Pollinator-mediated stabilizing selection (PMSS) has been proposed as the driver of the evolutionary shift from radial to bilateral symmetry of flowers. Studies have shown that variation in flower size is lower in bilateral than in radial species, but whether bilateral flowers experience more stabilizing selection pres... | ['Animals', 'Flowers', 'Insecta', 'Pollination'] | 19,710,062 | [['B01.050'], ['A18.024.249.500'], ['B01.050.500.131.617'], ['G08.686.784.743', 'G15.776']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developmental expression and androgen regulation of 24 kDa secretory proteins by the murine epididymis. | Two peptides with a molecular weight of 24 kDa and a P(i) of 8.4-8.8 were found to be synthesized and secreted specifically by the caput epididymis of adult male mice under androgen control. The peptides can interact with spermatozoa. In the present study, the developmental pattern of [35S]-methionine-labelled proteins... | ['Animals', 'Dihydrotestosterone', 'Electrophoresis, Gel, Two-Dimensional', 'Epididymis', 'Male', 'Methionine', 'Mice', 'Orchiectomy', 'Organ Culture Techniques', 'Protein Biosynthesis', 'Sulfur Radioisotopes', 'Testosterone'] | 8,514,427 | [['B01.050'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['E05.196.401.250', 'E05.301.300.230'], ['A05.360.444.371'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['B01.050.150.900.649.313.992.635.505.500'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Hemimelic epiphyseal dysplasia. Apropos of a case]. | Dysplasia epiphysealis hemimelica (tarsomegaly, Trevor's disease) is a rare osteochondrodystrophy producing cartilaginous epiphysial hypertrophy of hemimelic type involving mainly the lower limb. Lesions are generally medialy located (medial condyle of the femur, medial malleolus, talus, tarsal scaphoid and first metat... | ['Child, Preschool', 'Humans', 'Male', 'Osteochondrodysplasias', 'Radiography', 'Time Factors'] | 6,520,815 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.099.708', 'C16.320.728'], ['E01.370.350.700'], ['G01.910.857']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
NusG alters rho-dependent termination of transcription in vitro independent of kinetic coupling. | To complement the recent discovery that rho-dependent termination in E. coli requires nusG protein in vivo, we have tested the effect of purified nusG protein on rho-dependent termination in vitro. With the well-characterized trp t' terminator of E. coli, and no other proteins than E. coli RNA polymerase and rho factor... | ['Bacterial Proteins', 'Base Sequence', 'DNA, Bacterial', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Escherichia coli Proteins', 'Kinetics', 'Molecular Sequence Data', 'Peptide Elongation Factors', 'Point Mutation', 'RNA, Bacterial', 'Rho Factor', 'Suppression, Genetic', 'Terminator Regions, Genetic', 'Transc... | 7,505,669 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['D12.776.835.700'], ['G05.365.590.675'], ['D13.444.735.473... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anatomy of femoral vessels in infants and guidelines for venous catheterization. | This study was performed to formulate femoral venous catheterization guidelines for infants from ultrasound observations. Femoral vessels were evaluated on both sides in 75 infants, 2 weeks to 24 months of age. The site of the greatest probability of successful venipuncture 1 cm below the skin crease at the groin is lo... | ['Bloodletting', 'Catheterization, Peripheral', 'Femoral Artery', 'Femoral Vein', 'Humans', 'Infant', 'Infant, Newborn', 'Pulse', 'Reference Values', 'Ultrasonography'] | 2,657,622 | [['E02.800.558.500'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['A07.015.114.351'], ['A07.015.908.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.370.380.650', 'G09.330.380.750'], ['E05.978.810'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhancement of mammary tumor formation in mice by a cytostatic drug, melphalan. | Melphalan (L-phenylalanine mustard), a cytostatic drug used in treatment of human breast cancer, was injected into mice bearing preneoplastic hyperplastic alveolar nodule mammary outgrowth line D2. Melphalan, doses of either 2.5 or 5.0 mg/kg, markedly enhanced tumor formation in its mammary nodule outgrowth line. Sampl... | ['Animals', 'Carcinogens', 'Female', 'Humans', 'Hyperplasia', 'Mammary Neoplasms, Experimental', 'Melphalan', 'Mice', 'Mice, Inbred BALB C', 'Precancerous Conditions', 'Stimulation, Chemical'] | 830,417 | [['B01.050'], ['D27.888.569.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['D02.455.526.728.650.594', 'D12.125.072.050.685.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.99... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of the oxidative stress regulator PpYap1 through conserved cysteine residues during methanol metabolism in the yeast Pichia pastoris. | The methylotrophic yeast Pichia pastoris can grow on methanol as sole source of carbon and energy. The first reaction in yeast methanol metabolism, catalyzed by an abundant peroxisomal enzyme, alcohol oxidase, generates high levels of H(2)O(2), but the oxidative stress response during methanol metabolism has not been e... | ['Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'Cysteine', 'DNA Primers', 'Glutathione Peroxidase', 'Methanol', 'Molecular Sequence Data', 'Oxidative Stress', 'Pichia', 'Saccharomyces cerevisiae Proteins', 'Sequence Homology, Amino Acid', 'Transcription Factors'] | 19,502,720 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D08.811.682.732.500'], ['D02.033.623'], ['L01.453.245.667']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Facilitated recovery from postischemic suppression of protein synthesis in the gerbil brain with ischemic tolerance. | Preconditioning of the gerbil brain with a 2-min period of sublethal ischemia followed by 4 days of reperfusion protects against neuronal damage following a subsequent 3-min period of ischemia, which normally destroys pyramidal neurons in the CA1 region of the hippocampus. To clarify the role of protein synthesis in th... | ['Adaptation, Physiological', 'Animals', 'Autoradiography', 'Brain', 'Brain Ischemia', 'Gerbillinae', 'Hippocampus', 'Leucine', 'Male', 'Nerve Tissue Proteins', 'Reperfusion', 'Time Factors'] | 7,895,099 | [['G07.025', 'G16.012.500'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['B01.050.150.900.649.313.992.635.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.125.070.637', 'D12.125.142.441'], ['D12.776.631'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term results after high-dose radiotherapy and adjuvant hormones in prostate cancer: how curable is high-risk disease? | PURPOSE: To analyze long-term outcome and prognostic factors for high-risk prostate cancer defined by National Comprehensive Cancer Network criteria treated with high-dose radiotherapy and androgen deprivation in a single institution.METHODS AND MATERIALS: A total of 306 patients treated between 1995 and 2007 in a radi... | ['Aged', 'Androgen Antagonists', 'Disease-Free Survival', 'Dose-Response Relationship, Radiation', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Grading', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Treatment Outcome'] | 20,932,659 | [['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
27 years of a single burn centre experience with Stevens-Johnson syndrome and toxic epidermal necrolysis: analysis of mortality risk for causative agents. | INTRODUCTION: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life threatening unwanted side effects, mainly from medication. Pathophysiology is still being debated. The disease usually requires treatment in burn units.PATIENTS AND METHODS: In a retrospective study over 27 years we evaluated 72 ... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antimetabolites', 'Burn Units', 'Catecholamines', 'Female', 'Germany', 'Humans', 'Incidence', 'Length of Stay', 'Male', 'Middle Aged', 'Regression Analysis', 'Retrospective Studi... | 23,702,222 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.519.186', 'D27.888.569.042'], ['N02.278.388.493.160'], ['D02.092.3... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Frequency and predictors of renal artery stenosis in hypertensive patients undergoing coronary angiography. | Renal artery stenosis (RAS) and coronary artery disease share common risk factors. We investigated the frequency and predictors of RAS among hypertensive patients who underwent elective coronary angiography. A total of 832 hypertensive patients underwent coronary and renal angiography at the same session. Renal artery ... | ['Age Factors', 'Aged', 'Cohort Studies', 'Coronary Angiography', 'Coronary Artery Disease', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Prevalence', 'Renal Artery Obstruction', 'Risk Factors', 'Severity of Illness Index'] | 22,773,382 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['B01.050.... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Treatment of uncomplicated Plasmodium falciparum malaria in Myanmar: a clinical decision analysis. | This study was undertaken to compare cost-effectiveness of three drug regimes for treatment of uncomplicated falciparum malaria in Myanmar. The alternative regimens in this study were chloroquine (CQ), sulphadoxine-pyrimethamine (SP) and mefloquine (MFQ) along with their therapeutic efficacy in Myanmar. The study was p... | ['Antimalarials', 'Chloroquine', 'Cost-Benefit Analysis', 'Decision Support Techniques', 'Decision Trees', 'Drug Combinations', 'Humans', 'Malaria, Falciparum', 'Mefloquine', 'Myanmar', 'Pyrimethamine', 'Sulfadoxine', 'Treatment Failure', 'Treatment Outcome'] | 11,127,319 | [['D27.505.954.122.250.100.085'], ['D03.633.100.810.050.180'], ['N03.219.151.125'], ['E05.245', 'L01.313.500.750.190'], ['G17.162.500'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530.650', 'C01.920.875.650'], ['D03.633.100.810.410'], ['Z01.252.145.570'], ['D03.383.742.675'], ['D02.065.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Signalling mechanisms involved in the induction of inducible nitric oxide synthase by Lactobacillus rhamnosus GG, endotoxin, and lipoteichoic acid. | BACKGROUND AND AIMS: Probiotic Lactobacillus rhamnosus GG (Lactobacillus GG) has been found beneficial in the treatment of viral and antibiotic-associated diarrhea. Recently, it has also been shown to induce nitric oxide (NO) production, and have some other immunostimulatory effects. The aim of the present study was to... | ['Animals', 'Cell Line', 'Endotoxins', 'Enzyme Induction', 'Enzyme Inhibitors', 'Inflammation Mediators', 'Interferon-gamma', 'Lactobacillus', 'Lipopolysaccharides', 'Mice', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Signal Transduction', 'Teichoic Acids'] | 12,238,563 | [['B01.050'], ['A11.251.210'], ['D23.946.123.329'], ['G05.308.320.200'], ['D27.505.519.389'], ['D23.469'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['B03.353.750.450.475', 'B03.510.460.400.410.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increasing the efficiency of photodynamic therapy by improved light delivery and oxygen supply using an anticoagulant in a solid tumor model. | BACKGROUND AND OBJECTIVE: The main factors in photodynamic therapy (PDT) are: photosensitizer retention, photon absorption, and oxygen supply. Each factor has its unique set of problems that poses limitation to the treatment. Both light delivery and oxygen supply are significant bottlenecks in PDT. Vascular closure dur... | ['Animals', 'Anticoagulants', 'Blood Coagulation', 'Dihematoporphyrin Ether', 'Female', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Inbred BALB C', 'Necrosis', 'Oxygen', 'Photochemotherapy', 'Photosensitizing Agents', 'Reactive Oxygen Species'] | 20,740,620 | [['B01.050'], ['D27.505.954.502.119'], ['G09.188.390.150'], ['D03.383.129.578.840.500.462.400.200', 'D03.633.400.909.500.462.400.200', 'D04.345.783.500.462.400.200', 'D23.767.727.462.400.200'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal and early life influences on calcaneal ultrasound parameters and metacarpal morphometry in 7- to 9-year-old children. | We investigated the relationship between maternal and early life influences, calcaneal ultrasound parameters, and metacarpal morphometry in 7- to 9-year-old children (n = 109) of mixed ancestral origin from a working class community. Their mothers had participated in a nutrition and pregnancy study at the time of the b... | ['Birth Weight', 'Bone Density', 'Calcaneus', 'Child', 'Female', 'Humans', 'Male', 'Metacarpus', 'Motor Activity', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Radiography', 'Regression Analysis', 'Smoking', 'Socioeconomic Factors', 'Ultrasonography'] | 16,622,737 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['G11.427.100'], ['A02.835.232.043.300.710.300'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.800.667.572'], ['F01.145.632', 'G11.427.410.698'], ['G08... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Plasma porphyrins in chronic renal failure. | Using a quantitative sensitive HPLC fluorometric assay for the measurement of plasma and urine porphyrins, we have calculated the renal clearance of uro- and coproporphyrin in normal volunteers and in patients with congenital erythropoietic porphyria and hereditary coproporphyria (HCP). In patients with porphyria cutan... | ['Adult', 'Aged', 'Chromatography, High Pressure Liquid', 'Coproporphyrins', 'Creatinine', 'Female', 'Humans', 'Kidney', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Porphyrias', 'Porphyrins', 'Uroporphyrins'] | 2,362,629 | [['M01.060.116'], ['M01.060.116.100'], ['E05.196.181.400.300'], ['D03.383.129.578.840.500.250', 'D03.633.400.909.500.250', 'D04.345.783.500.250', 'D23.767.727.250'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Keratin subsets in papillary and follicular thyroid lesions. A paraffin section analysis with diagnostic implications. | Previous studies indicate that keratins 7, 8 and 18 are present in all thyroid papillary and follicular lesions, but the distribution of other keratins has been incompletely characterized. The profile of individual keratin (K) polypeptides was evaluated immunohistochemically in over 200 non-neoplastic and neoplastic th... | ['Adenocarcinoma, Follicular', 'Adenoma', 'Carcinoma, Papillary', 'Diagnosis, Differential', 'Goiter', 'Humans', 'Immunohistochemistry', 'Keratins', 'Thyroid Neoplasms'] | 9,428,928 | [['C04.557.470.200.025.060'], ['C04.557.470.035'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['E01.171'], ['C19.874.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypofractionated versus conventionally fractionated radiotherapy for patients with localised prostate cancer (HYPRO): final efficacy results from a randomised, multicentre, open-label, phase 3 trial. | BACKGROUND: Studies have reported a low á/â ratio for prostate cancer, suggesting that hypofractionation could enhance the biological tumour dose without increasing genitourinary and gastrointestinal toxicity. In the multicentre phase 3, HYpofractionated irradiation for PROstate cancer (HYPRO) trial, hypofractionated r... | ['Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Neoplasm Grading', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Prostatic Neoplasms', 'Radiation Dose Hypofractionation', 'Radiotherapy, Intensity-Modulated', 'Survival Rate', 'Treatment Outcome'] | 27,339,116 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.612'], ['C04.697.655', 'C23.550.727.655'], ['E01.789.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
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