Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Ultrastructural studies on the formation and distribution of lipid droplets in the lung capillary endothelial cells in patients with sarcoidosis. | BACKGROUND AND AIM OF THE WORK: We previously reported the presence of definite morphological alterations in the capillary endothelium of sarcoid lung. The aim of this study was to examine ultrastructural changes and distribution of lipid droplets in the endothelium of lung capillaries of patients with sarcoidosis.METH... | ['Adult', 'Capillaries', 'Endothelium, Vascular', 'Fatty Acids', 'Fatty Acids, Unsaturated', 'Female', 'Humans', 'Lipid Metabolism', 'Lung', 'Male', 'Middle Aged', 'Pericytes', 'Sarcoidosis, Pulmonary'] | 10,207,943 | [['M01.060.116'], ['A07.015.461.165'], ['A07.015.700.500', 'A10.272.491.355'], ['D10.251'], ['D10.251.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['A04.411'], ['M01.060.116.630'], ['A07.015.700.750', 'A10.272.491.677', 'A11.710', 'A16.504.660.600'], ['C08.381.483.725', 'C15.604.515.827.725']] | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Partial weight bearing after operations for hip fractures in elderly patients. | Factors affecting a patient's ability to carry out partial weight bearing after operation for hip fracture were studied in 100 patients. Seventy-six were able to do so. Significant factors included the muscle power of the good limbs and the mental state, whereas age, body-weight and type of operation were not significa... | ['Aged', 'Aged, 80 and over', 'Female', 'Hip Fractures', 'Hip Joint', 'Humans', 'Male', 'Middle Aged', 'Weight-Bearing'] | 1,383,527 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G01.374.965']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Guanine nucleotide exchange factor for eukaryotic initiation factor-2. Cloning of cDNA for the delta-subunit of rabbit translation initiation factor-2B. | Peptide sequence data for rabbit eIF-2B delta were obtained and used to design redundant oligonucleotides for PCR. RNA was isolated from rabbit liver and used to direct the synthesis of total cDNA. A rabbit eIF-2B delta transcript was then amplified by PCR and sequenced. The PCR product was used to isolate a clone from... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'DNA, Complementary', 'Eukaryotic Initiation Factor-2', 'Eukaryotic Initiation Factor-2B', 'Fungal Proteins', 'Guanine Nucleotide Exchange Factors', 'Liver', 'Molecular Sequence Data', 'Oligonucleotides', 'Proteins', 'Rabbits', 'Repressor Protein... | 8,110,836 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.835.725.868.249'], ['D12.644.360.325.300.050', 'D12.776.476.325.300.050', 'D12.776.835.725.868.37... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Differentiation and Identification of Alicyclobacillus Strains by Fourier Transform Near-Infrared Spectroscopy]. | Fourier transform near-infrared spectroscopy (FT-NIR) can reflect the overall molecular composition of microbial cells to identify different types of microorganisms. To establish an accurate, effective method about the differentiation and identification of Alicyclobacillus strains between different species, the present... | ['Alicyclobacillus', 'Spectroscopy, Fourier Transform Infrared'] | 26,978,911 | [['B03.353.500.050', 'B03.510.100.050', 'B03.510.415.400.078'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retrohepatic vena cava and hepatic vein injuries: a simplified experimental methods of treatment by balloon shunt. | BACKGROUND: Fecal contamination from colon injury has been thought to be the most significant factor for the development of surgical site infection (SSI) after trauma. However, there are increasing data to suggest that other factors may play a role in the development of postinjury infection in patients after colon inju... | ['Abdominal Injuries', 'Animals', 'Catheterization', 'Constriction', 'Dogs', 'Hepatic Veins', 'Vena Cava, Inferior'] | 14,960,995 | [['C26.017'], ['B01.050'], ['E02.148', 'E05.157'], ['E05.225'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.015.908.380'], ['A07.015.908.949.648']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two-stage surgical approach with dermofat graft and lipofilling for the treatment of established Frey syndrome and facial depression deformity. | Frey syndrome and facial contour deformity commonly occur after parotid surgery. Although the treatment of established Frey syndrome has focused on medical solutions, surgical solutions to established Frey syndrome have been less reported. Moreover, these methods may not resolve the facial depression. In the presented ... | ['Adipose Tissue', 'Cicatrix', 'Face', 'Humans', 'Male', 'Parotid Gland', 'Postoperative Complications', 'Sweating, Gustatory', 'Young Adult'] | 22,801,164 | [['A10.165.114'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['C23.550.767'], ['C10.177.825', 'C17.800.946.350.843'], ['M01.060.116.815']] | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The accumulation and localization of chalcone synthase in grapevine (Vitis vinifera L.). | Chalcone synthase (CHS, E.C.2.3.1.74) is the first committed enzyme in the flavonoid pathway. Previous studies have primarily focused on the cloning, expression and regulation of the gene at the transcriptional level. Little is yet known about the enzyme accumulation, regulation at protein level, as well as its localiz... | ['Acyltransferases', 'Flavonoids', 'Fruit', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Immunohistochemistry', 'Organ Specificity', 'Plant Leaves', 'Plant Roots', 'Protein Transport', 'RNA, Messenger', 'Subcellular Fractions', 'Vitis'] | 27,161,583 | [['D08.811.913.050'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G05.308.320'], ['G05.308.375'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. | The X-ray structures of 1 Fv and 2 Fab humanized anti-p185HER2 antibody fragments (IgG1-kappa) have been determined at a resolution between 2.7 A and 2.2 A. The antibodies are three different versions of a human antibody framework onto which the antigen recognition loops from a murine antibody (4D5) have been grafted. ... | ['Amino Acid Sequence', 'Animals', 'Antibodies', 'Binding Sites, Antibody', 'Computer Simulation', 'Humans', 'Hydrogen Bonding', 'Immunoglobulin Variable Region', 'Mice', 'Models, Molecular', 'Molecular Sequence Data', 'Oncogene Proteins, Viral', 'Protein Conformation', 'Receptor, ErbB-2', 'Sequence Homology, Amino Aci... | 8,095,303 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['D12.644.541.500.650.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Underlying pathology of women with "atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion" smears, in a region with a high incidence of cervical cancer. | AIM: To evaluate the histopathology of women who had "atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesions" (ASC-H) on cervical cytology in a region with high incidence of cervical cancer.METHODS: This study was conducted at Chiang Mai University Hospital, Chiang Mai, Thailand. All women ... | ['Adult', 'Cervical Intraepithelial Neoplasia', 'Cohort Studies', 'Colposcopy', 'Female', 'Histocytochemistry', 'Humans', 'Middle Aged', 'Neoplasms, Squamous Cell', 'Papanicolaou Test', 'Prospective Studies', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 18,412,783 | [['M01.060.116'], ['C04.557.470.200.240.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Current progress in the development of a totally implantable Gyro centrifugal artificial heart. | A totally implantable centrifugal artificial heart has been developed using a miniaturized pivot bearing supported centrifugal pump (Gyro PI pump). The authors report current progress in its development. The Gyro PI-601 has a priming volume of 20 ml, weighs 100 g, has a height of 60 mm, and has a diameter of 65 mm. Thi... | ['Alloys', 'Animals', 'Biocompatible Materials', 'Blood Flow Velocity', 'Cattle', 'Centrifugation', 'Feasibility Studies', 'Heart, Artificial', 'Heart-Assist Devices', 'Humans', 'Thromboembolism', 'Titanium'] | 9,617,953 | [['D01.552.033', 'D25.058', 'J01.637.051.058'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.500.380.271'], ['E05.181'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E07.695.300', 'E07.858.082... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Hepatitis B virus (HBV) serum markers in Greek leprosy patients. | The prevalence of HBsAg, anti-HBs, and anti-HBc in the sera of 217 patients with the two polar types of leprosy and 382 hospital controls was studied in order to investigate the degree of exposure of Greek leprosy patients to HBV and the ability of these patients to clear HBV from the blood. Two distinct serological pa... | ['Adult', 'Age Factors', 'Female', 'Greece', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Core Antigens', 'Hepatitis B Surface Antigens', 'Humans', 'Leprosy', 'Male', 'Middle Aged'] | 3,722,963 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.542.383'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.715.548.114.254.450.504'], ['D23.050.327.495.500.450'], ['D23.050.3... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of heterotrophic plate count bacteria isolated from drinking water in Japan by DNA sequencing analysis. | Heterotrophic plate count (HPC) test has been employed to indicate the effectiveness of water treatment processes and the microbiological condition of the distribution system. In Japan, because the majority of HPC bacteria are supposed to be harmless and all tap water should maintain residual chlorine, there are few st... | ['Bacteria', 'Colony Count, Microbial', 'DNA, Bacterial', 'Humans', 'Polymerase Chain Reaction', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Virulence', 'Water Microbiology', 'Water Supply'] | 20,055,218 | [['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D13.444.308.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500'], ['D13.444.735.686.670'], ['E05.393.760.700'], ['G06.930'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['J01.293.821.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Evaluation of dental morphometrics during the orthodontic treatment. | BACKGROUND: Diagnostic orthodontic and prosthetic procedures commence with an initial examination, during which a number of individual findings on occlusion or malocclusion are clarified. Nowadays we try to replace standard plaster casts by scanned objects and digital models.METHOD: Geometrically calibrated images aid ... | ['Casts, Surgical', 'Computer Simulation', 'Humans', 'Orthodontics', 'Regression Analysis', 'Software', 'Tooth'] | 24,893,983 | [['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.658', 'H02.163.876.439'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['L01.224.900'], ['A14.549.167.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
N-terminal parathyroid hormone-related protein levels in human intrauterine growth restricted pregnancies. | BACKGROUND: N-terminal parathyroid hormone-related protein has a vital role in regulating cell growth and differentiation, uteroplacental vasodilatation, uterine muscle relaxation, and placental transport. These functions are compromised in intrauterine growth restriction. We aimed to investigate N-terminal parathyroid... | ['Adult', 'Birth Weight', 'Case-Control Studies', 'Female', 'Fetal Blood', 'Fetal Growth Retardation', 'Fetus', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Male', 'Parathyroid Hormone-Related Protein', 'Pregnancy'] | 17,653,879 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['C13.703.277.370', 'C16.300.390', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells. | NF-kappaB is constitutively active in many solid tumors, including breast cancer. However, the role of NF-kappaB in breast carcinogenesis is unknown. Ikkalpha(AA/AA) "knockin" mice in which activation of IkappaB kinase alpha (IKKalpha) is prevented by replacement of activation loop serines with alanines exhibit delayed... | ['Animals', 'Breast Neoplasms', 'Carrier Proteins', 'Enzyme Activation', 'Female', 'Genes, erbB-2', 'I-kappa B Kinase', 'Intracellular Signaling Peptides and Proteins', 'Mammary Neoplasms, Animal', 'Mice', 'Mice, Transgenic', 'NF-kappa B', 'Precancerous Conditions'] | 17,890,319 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.157'], ['G02.111.263', 'G03.328'], ['G05.360.340.024.340.375.500.791.295.305'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['D12.644.360', 'D12.776.476'], ['C04.588.531', 'C22.520'], ['B01.050.150.900.649.313.992.635.505.500'], ... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reach performance and postural adjustments during standing in children with severe spastic diplegia using dynamic ankle-foot orthoses. | OBJECTIVE: To investigate the co-ordination between reaching, ground reaction forces and muscle activity in standing children with severe spastic diplegia wearing dynamic ankle-foot orthoses compared with typically developing children.DESIGN: Clinical experimental study.SUBJECTS: Six children with spastic diplegia (Gro... | ['Ankle', 'Cerebral Palsy', 'Child', 'Child, Preschool', 'Equipment Design', 'Foot', 'Humans', 'Motor Skills', 'Movement', 'Muscle Spasticity', 'Orthotic Devices', 'Posture'] | 17,999,010 | [['A01.378.610.050'], ['C10.228.140.140.254'], ['M01.060.406'], ['M01.060.406.448'], ['E05.320'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808.260'], ['G07.568', 'G11.427.410'], ['C05.651.512', 'C10.597.613.550.550', 'C23.888.592.608.550.550'], ['E07.858.442.743'], ['G11.427.695']] | ['Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Morphological factors and cardiac doses in whole breast radiation for left-sided breast cancer. | BACKGROUND: To investigate the impact of the breast size, shape, maximum heart depth (MDH), and chest wall hypotenuse (the distance connecting middle point of the sternum and the length of lung draw on the selected transverse CT slice) on the volumetric dose to heart with whole breast irradiation (WBI) of left-sided br... | ['Adult', 'Aged', 'Breast', 'Female', 'Heart', 'Humans', 'Middle Aged', 'Radiation', 'Radiotherapy Dosage', 'Radiotherapy, Intensity-Modulated', 'Thorax', 'Unilateral Breast Neoplasms'] | 25,854,378 | [['M01.060.116'], ['M01.060.116.100'], ['A01.236'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G01.750'], ['E02.815.639'], ['E02.815.635.700.700', 'L01.313.500.750.100.710.600.550.700'], ['A01.923.761'], ['C04.588.180.800', 'C17.800.090.500.682']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Highly conserved D-loop-like nuclear mitochondrial sequences (Numts) in tiger (Panthera tigris). | Using oligonucleotide primers designed to match hypervariable segments I (HVS-1) of Panthera tigris mitochondrial DNA (mtDNA), we amplified two different PCR products (500 bp and 287 bp) in the tiger (Panthera tigris), but got only one PCR product (287 bp) in the leopard (Panthera pardus). Sequence analyses indicated t... | ['Animals', 'Base Sequence', 'Cell Nucleus', 'Complementarity Determining Regions', 'Conserved Sequence', 'DNA, Mitochondrial', 'Evolution, Molecular', 'Genetic Variation', 'Mitochondria', 'Molecular Sequence Data', 'NADH Dehydrogenase', 'Phylogeny', 'Sequence Alignment', 'Tigers'] | 17,072,079 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.644.541.500.650.500.180', 'D12.776.124.486.485.680.650.500.180', 'D12.776.124.486.485.797.180', 'D12.776.124.790.651.680.650.500.180', 'D12.776.124.790.651.797.180', 'D12.776.377.715.548.68... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Factors associated with poorly-controlled hypertension in continuous ambulatory peritoneal dialysis patients. | INTRODUCTION: Hypertension is highly prevalent among continuous ambulatory peritoneal dialysis (CAPD) patients and is a major risk factor for cardiovascular complications. This study examines the risk factors associated with poorly-controlled hypertension in CAPD.METHODS: We performed a cross-sectional study of 66 stab... | ['Adult', 'Antihypertensive Agents', 'Blood Volume', 'Cross-Sectional Studies', 'Diet, Sodium-Restricted', 'Female', 'Humans', 'Hypertension', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Patient Compliance', 'Peritoneal Dialysis, Continuous Ambulatory', 'Risk Factors', 'Risk-Taking'] | 15,510,323 | [['M01.060.116'], ['D27.505.954.411.162'], ['G09.188.130', 'G09.330.380.092'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.642.249.290', 'G07.203.650.240.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ca(2+) spiking activity caused by the activation of store-operated Ca(2+) channels mediates TNF-á release from microglial cells under chronic purinergic stimulation. | Cytokines released from microglia mediate defensive responses in the brain, but the underlying mechanisms are obscure. One proposed process is that nucleotide leakage or release from surrounding cells is sensed by metabotropic (P2Y) and ionotropic (P2X) purinergic receptors, which may trigger long-term intracellular Ca... | ['Adenosine Triphosphate', 'Adenoviridae', 'Animals', 'Calcium', 'Calcium Channels', 'Calcium Signaling', 'Cell Line', 'Cell Survival', 'Cytosol', 'Dendrites', 'Gene Expression Profiling', 'Intracellular Space', 'Mice', 'Mice, Inbred C57BL', 'Microglia', 'Models, Biological', 'Purinergic P2X Receptor Antagonists', 'Pyr... | 23,830,920 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B04.280.030'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A retrospective analysis in patients with EGFR-mutant lung adenocarcinoma: is EGFR mutation associated with a higher incidence of brain metastasis? | Lung adenocarcinomas are more commonly associated with brain metastases (BM). Epidermal growth factor receptor (EGFR) mutations have been demonstrated to be both predictive and prognostic for patients with lung adenocarcinoma. We aimed to explore the potential association between EGFR mutation and the risk of BM in pul... | ['Adenocarcinoma', 'Adenocarcinoma of Lung', 'Adult', 'Aged', 'Aged, 80 and over', 'Brain Neoplasms', 'DNA Mutational Analysis', 'ErbB Receptors', 'Exons', 'Female', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Mutation', 'Neoplasm Metastasis', 'Prog... | 27,486,770 | [['C04.557.470.200.025'], ['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.393.760.700.300'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conversion of sunflower oil to biodiesel by alcoholysis using immobilized lipase. | Transesterification reaction was performed using sunflower oil and short-chain alcohol by immobilized lipases in organic solvents. The fatty acid ester, which is the product of this reaction, can be used as a diesel fuel that does not produce sulfur oxide and minimize the soot particulate. Immobilized porcine pancreati... | ['Alcohols', 'Allosteric Site', 'Animals', 'Candida', 'Catalysis', 'Diatomaceous Earth', 'Enzyme Reactivators', 'Enzyme Stability', 'Enzymes, Immobilized', 'Esterification', 'Fatty Acids', 'Gasoline', 'Pancrelipase', 'Plant Oils', 'Substrate Specificity', 'Sunflower Oil', 'Swine'] | 18,437,590 | [['D02.033'], ['G02.111.570.120.147'], ['B01.050'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['G02.130'], ['D01.578.750.300', 'D01.650.550.825.400', 'D01.837.725.400'], ['D27.505.519.405'], ['E05.916.360', 'G02.111.700.500'], ['D08.811.180', 'D12.776.463.500'], ['G02.111.270', 'G02.607.250', 'G03.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cognitive rehabilitation for executive dysfunction in brain tumor patients: a pilot randomized controlled trial. | PURPOSE: Patients with brain tumors face unique quality of life challenges. Executive dysfunction is common and functionally limiting, with no established treatments as standard care. This pilot study evaluated the efficacy of Goal Management Training (GMT), a behavioral intervention combining mindfulness and strategy ... | ['Adult', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Cognition Disorders', 'Cognitive Behavioral Therapy', 'Executive Function', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Pilot Projects', 'Quality of Life', 'Surveys and Questionnaires', 'Treatment Outcome'] | 30,847,839 | [['M01.060.116'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['F03.615.250'], ['F04.754.137.350'], ['F02.463.217'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Skeletal muscle oxygen availability during respiratory acid-base disturbances in cats. | Respiratory acid-base disorders elicit physiological responses that alter O2 delivery to various tissues. We have used a near infrared (NIR) optical technique to monitor cytochrome a,a3 oxidation state, tissue O2 store (relative hemoglobin plus myoglobin oxygenation), and regional blood volume in intact resting skeleta... | ['Acidosis, Respiratory', 'Alkalosis, Respiratory', 'Animals', 'Blood Circulation', 'Blood Gas Analysis', 'Blood Pressure', 'Cats', 'Electron Transport Complex IV', 'Female', 'Hemoglobins', 'Hindlimb', 'Hypercapnia', 'Male', 'Muscles', 'Myoglobin', 'Oxidation-Reduction', 'Oxygen Consumption'] | 2,823,360 | [['C08.618.846.093', 'C18.452.076.176.310'], ['C08.618.501.271', 'C18.452.076.354.271'], ['B01.050'], ['G09.330.100'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D05.500.562.374', 'D08.811.600.... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histochemical and fluorescent techniques for detection of early myocardial ischemia following experimental coronary artery occlusion: a comparative and quantitative study. | Several workers have used histochemical, enzymatic, and fluorescent methods to diagnose early myocardial ischemia, but the problem of unequivocal detection of early ischemia still remains an enigma to pathologists. In the present study, the left coronary artery was ligated in an animal model, rat, in order to produce m... | ['Acridine Orange', 'Analysis of Variance', 'Animals', 'Female', 'Fluorescence', 'Histocytochemistry', 'Male', 'Myocardial Infarction', 'Myocardium', 'Necrosis', 'Nitroblue Tetrazolium', 'Oxidoreductases', 'Rats', 'Rats, Inbred Strains', 'Staining and Labeling', 'Tetrazolium Salts', 'Time Factors'] | 2,450,489 | [['D03.633.300.046.250.150'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['C14.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Bactericidal properties of Campylobacter jejuni-specific immunoglobulin M antibodies in commercial immunoglobulin preparations. | Campylobacter jejuni is one of the most common enterocolitis-causing microorganisms worldwide. It is of particular importance in immunodeficient patients, who frequently are prone to develop extraintestinal manifestations. Since these cases respond poorly to antibiotic treatment, a supportive immunomodulating therapy i... | ['Antibodies, Bacterial', 'Bacterial Outer Membrane Proteins', 'Campylobacter jejuni', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Immunoblotting', 'Immunoglobulin M', 'In Vitro Techniques', 'Lipopolysaccharides', 'Luminescent Measurements', 'Microbial Sensitivity Tests', 'Neutrophils', 'Serotyping'] | 8,540,699 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.097.120', 'D12.776.543.100'], ['B03.440.180.425', 'B03.660.150.235.250.500.375'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Embolization of orbital varices with N-butyl cyanoacrylate as an aid in surgical excision: results of 4 cases with histopathologic examination. | PURPOSE: To report the results of intervention with percutaneously injected n-butyl cyanoacrylate (NBCA) to embolize orbital varices followed by surgical resection.DESIGN: Retrospective case series.METHODS: Four patients with symptomatic orbital varices were treated with percutaneous injection of NBCA to embolize the v... | ['Adult', 'Embolization, Therapeutic', 'Enbucrilate', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Orbit', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Ultrasonography, Doppler', 'Varicose Veins'] | 19,541,289 | [['M01.060.116'], ['E02.520.360', 'E02.926.500'], ['D02.241.081.069.366.350', 'D02.626.290.350', 'D05.750.259.341', 'D25.720.259.341', 'D25.919.367.341', 'J01.637.051.720.259.341', 'J01.637.051.919.367.341'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Color-coded duplex sonography of experimentally induced multilevel stenosis. Evaluation of poststenotic Doppler spectrum. | RATIONALE AND OBJECTIVES: The authors evaluated the influence of a proximal arterial stenosis on the poststenotic doppler spectrum of a second, distal stenosis and determined duplex parameters, which permitted description of the severity of the distal stenosis.METHODS: Moderate (ie, 50%) and severe (ie, 90%) stenoses o... | ['Animals', 'Aorta', 'Arterial Occlusive Diseases', 'Blood Flow Velocity', 'Female', 'Femoral Artery', 'Iliac Artery', 'Swine', 'Ultrasonography, Doppler, Color', 'Ultrasonography, Doppler, Duplex'] | 9,228,604 | [['B01.050'], ['A07.015.114.056'], ['C14.907.137'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A07.015.114.351'], ['A07.015.114.444'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.850.850.850.850'], ['E01.370.350.850.850.850']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
'Whore stigma' as a transformative experience: altered cognitive expectations among Jewish-Israeli street-based sex workers. | While the scholarship on sex work is substantial, it neglects to explore whether sex work and associated stigma affect sex workers' cognitive expectations. Drawing on observations of street-based sex work as well as in-depth interviews with Jewish-Israeli sex workers, this study suggests that because stigma is a moral ... | ['Adult', 'Anthropology, Cultural', 'Female', 'Humans', 'Interviews as Topic', 'Israel', 'Jews', 'Middle Aged', 'Qualitative Research', 'Sex Workers', 'Social Stigma', 'Violence'] | 28,276,917 | [['M01.060.116'], ['I01.076.201'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.252.245.500.375'], ['M01.686.754.600'], ['M01.060.116.630'], ['H01.770.644.241.850'], ['M01.776'], ['F01.145.813.840'], ['I01.198.240.856', 'I01... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Exact sequence variants should replace operational taxonomic units in marker-gene data analysis. | Recent advances have made it possible to analyze high-throughput marker-gene sequencing data without resorting to the customary construction of molecular operational taxonomic units (OTUs): clusters of sequencing reads that differ by less than a fixed dissimilarity threshold. New methods control errors sufficiently suc... | ['Bacteria', 'Classification', 'Databases, Nucleic Acid', 'Genetic Variation', 'Sequence Analysis, DNA'] | 28,731,476 | [['B03'], ['L01.100', 'L01.453.245.275'], ['L01.313.500.750.300.188.400.300.500', 'L01.313.500.750.300.188.400.325.630', 'L01.470.750.750.300.500', 'L01.470.750.750.325.630'], ['G05.365'], ['E05.393.760.700']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Erythrocyte folate content and serum folic acid and homocysteine levels in preeclamptic primigravidae teenagers living at high altitude. | OBJECTIVE: To measure erythrocyte folate content and serum folic acid and homocysteine (Hcy) levels in preeclamptic primigravidae teenagers living at high altitude.METHODS: Measured analytes were compared to those found in normal teen controls.RESULTS: Teenagers complicated with preeclampsia displayed significantly low... | ['Adolescent', 'Adult', 'Altitude', 'Case-Control Studies', 'Erythrocytes', 'Female', 'Folic Acid', 'Gravidity', 'Hematocrit', 'Homocysteine', 'Humans', 'Pilot Projects', 'Pre-Eclampsia', 'Pregnancy', 'Young Adult'] | 23,609,037 | [['M01.060.057'], ['M01.060.116'], ['G16.500.275.058', 'N06.230.058'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D03.633.100.733.631.400'], ['G08.686.340', 'G08.686.784.769.213', 'N06.850.490.812.250'], ['E01.370.225.625.400', 'E0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of the mutational spectrum of the FGFR2 gene in Pfeiffer syndrome. | Pfeiffer syndrome (PS) is one of the classical craniosynostosis syndromes correlated with specific mutations in the human fibroblast growth factor receptor (FGFR) genes, FGFR1 and FGFR2. In this study, we set out to examine the exons in FGFR2 most commonly associated with mutations in PS, exons IIIa and IIIc, in a pane... | ['Acrocephalosyndactylia', 'Alternative Splicing', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Codon', 'Cysteine', 'Exons', 'Humans', 'Molecular Sequence Data', 'Mutation', 'Mutation, Missense', 'Point Mutation', 'Protein Conformation', 'Receptor Protein-Tyrosine Kinases', 'Receptor, Fibroblast Growth Factor, Ty... | 10,394,936 | [['C05.116.099.370.894.232.015', 'C05.116.099.370.894.819.100', 'C05.660.207.240.100', 'C05.660.585.800.100', 'C05.660.906.364.100', 'C05.660.906.819.100', 'C16.131.621.207.240.100', 'C16.131.621.585.800.100', 'C16.131.621.906.364.100', 'C16.131.621.906.819.100'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Examining the validity of DSM-III-R schizoaffective disorder and its putative subtypes in the Roscommon Family Study. | OBJECTIVE: The authors sought to assess whether the DSM-III-R category of schizoaffective disorder differs meaningfully from schizophrenia and affective illness in clinical features, outcome, and familial psychopathology. In addition, the authors evaluated the validity of two proposed subtyping systems for schizoaffect... | ['Adolescent', 'Adult', 'Aged', 'Bipolar Disorder', 'Comorbidity', 'Depressive Disorder', 'Diagnosis, Differential', 'Family', 'Female', 'Follow-Up Studies', 'Humans', 'Ireland', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Psychotic Disorders', 'Registries', 'Reproducibility of Results', 'Schizophrenia'... | 7,726,316 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.300'], ['E01.171'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis. | BACKGROUND: Melatonin generated in the gastrointestinal tract has mucosal protective effect with inhibiting gastric acid secretion, while increasing gastrin release, which in turn stimulates the contractility of lower esophageal sphincter. Gastroesophageal reflux disease (GERD) is also known to have association with sl... | ['Central Nervous System Depressants', 'Gastroesophageal Reflux', 'Humans', 'Melatonin', 'Meta-Analysis as Topic', 'Receptors, Melatonin', 'Research Design', 'Systematic Reviews as Topic', 'Treatment Outcome'] | 30,681,611 | [['D27.505.696.277', 'D27.505.954.427.210'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.914.481', 'D06.472.506'], ['E05.318.370.500', 'E05.581.500.501', 'N05.715.360.325.515', 'N06.850.520.445.500'], ['D12.776.543.750.695.440', 'D12.776.826.590'], ['E05.581.500', 'H0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Pulsed radio frequency therapy of experimentally induced arthritis in ponies. | The effect of pulsed radio frequency therapy (PRFT) was evaluated on seven ponies with no arthritis and in 28 ponies in which arthritis was created using intra-articular amphotericin B to induce synovitis in the right middle carpal joint. The ponies were divided into five treatment and two control groups. Two levels of... | ['Animals', 'Arthritis', 'Carpus, Animal', 'Dose-Response Relationship, Radiation', 'Horse Diseases', 'Horses', 'Lameness, Animal', 'Radio Waves'] | 1,884,288 | [['B01.050'], ['C05.550.114'], ['A13.395.248'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C22.510'], ['G01.358.500.505.810', 'G01.750.250.810', 'G01.750.770.721']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pseudomonas syringae pv. phaseolicola can be separated into two genetic lineages distinguished by the possession of the phaseolotoxin biosynthetic cluster. | The bean (Phaseolus spp.) plant pathogen Pseudomonas syringae pv. phaseolicola is characterized by the ability to produce phaseolotoxin (Tox(+)). We recently reported that the majority of the Spanish P. syringae pv. phaseolicola population is unable to synthesize this toxin (Tox(-)). These Tox(-) isolates appear to lac... | ['Base Sequence', 'Conserved Sequence', 'DNA Primers', 'Exotoxins', 'Molecular Sequence Data', 'Multigene Family', 'Ornithine', 'Phylogeny', 'Polymerase Chain Reaction', 'Pseudomonas syringae'] | 14,766,926 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D23.946.350'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['D12.125.068.665', 'D12.125.095.765'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500'], ['B03.44... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Biomolecule-quantum dot systems for bioconjugation applications. | In the present work, it is reported for the first time the bioconjugation of CdS quantum dots (QDs) directly with bovine serum albumin (BSA) using a one-step procedure via aqueous route at room temperature by methods of colloidal chemistry. Essentially, the bioconjugates were developed based on BSA as capping ligand fo... | ['Animals', 'Cadmium Compounds', 'Cattle', 'Colloids', 'Models, Biological', 'Nanoparticles', 'Quantum Dots', 'Serum Albumin, Bovine', 'Sulfides'] | 21,353,498 | [['B01.050'], ['D01.142'], ['B01.050.150.900.649.313.500.380.271'], ['D20.280', 'D26.255.165'], ['E05.599.395'], ['J01.637.512.600'], ['E07.705', 'J01.637.512.600.650'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells. | Sanguinarine, a plant alkaloid, was identified as a potent and specific protein phosphatase (PP) 2C inhibitor. It inhibited PP2C competitively with respect to alpha-casein (Ki=0.68 microM) and showed selectivity for PP2C as compared with PP1, PP2A, and PP2B in vitro. In vivo, sanguinarine showed cytotoxicity toward hum... | ['Apoptosis', 'Benzophenanthridines', 'Caspase 3', 'Caspase 7', 'Enzyme Inhibitors', 'HL-60 Cells', 'Humans', 'Imidazoles', 'Isoquinolines', 'Phosphoprotein Phosphatases', 'Phosphorylation', 'Protein Phosphatase 2C', 'Pyridines', 'p38 Mitogen-Activated Protein Kinases'] | 20,208,361 | [['G04.146.954.035'], ['D03.132.089', 'D03.633.300.633.207', 'D03.633.400.131'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126.350.700', 'D08.811.277.656.300.200.126.350.700', 'D12.644.360.075.4... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment and prevention of relapse of mild oesophagitis with omeprazole and cisapride: comparison of two strategies. | BACKGROUND: Oesophagitis is usually a chronic condition. Healing with omeprazole is often followed by early relapse. Combination treatment and subsequent maintenance treatment with the prokinetic cisapride may be of benefit in relapse prevention.METHODS: Patients with endoscopically proven oesophagitis, grade I (n = 12... | ['Adult', 'Aged', 'Cisapride', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Esophagitis, Peptic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Omeprazole', 'Piperidines', 'Recurrence'] | 7,654,890 | [['M01.060.116'], ['M01.060.116.100'], ['D02.065.277.135', 'D02.241.223.100.050.500.644', 'D02.241.223.100.100.135', 'D02.241.223.100.200.374', 'D02.455.426.559.389.127.020.937.700', 'D02.455.426.559.389.127.085.135', 'D02.455.426.559.389.127.250.374', 'D03.383.621.135'], ['E02.319.283'], ['E02.319.310'], ['C06.405.117... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of caffeine effects on biochemical and genotoxic biomarkers in the neotropical freshwater teleost Prochilodus lineatus. | Caffeine is often found in aquatic environments, leading to concerns regarding its adverse consequences for aquatic biota. Biochemical and genotoxic biomarkers were analysed in juveniles of Prochilodus lineatus to evaluate the effects of caffeine. Fish were exposed to caffeine (0.3, 3 and 30 ìg L-1) for either 24 h or ... | ['Animals', 'Biomarkers', 'Brain', 'Caffeine', 'Characiformes', 'Cytochrome P-450 CYP1A1', 'DNA Damage', 'Erythrocytes', 'Glutathione', 'Glutathione Transferase', 'Lipid Peroxidation', 'Liver', 'Water Pollutants, Chemical'] | 29,438,913 | [['B01.050'], ['D23.101'], ['A08.186.211'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['B01.050.150.900.493.130'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.220.453.010.332', 'D12.776.422.220.453.100.500'], ['G05.200'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Counting efficiency of some commercially available liquid scintillators compared. | We investigated four commercially available liquid scintillators as to overall counting efficiency and quenching effect of added phosphate-buffered isotonic saline. They differed significantly in these respects. Evidently, characteristics of the scintillator used in radioimmunoassays where beta-particle emitters are co... | ['Buffers', 'Phosphates', 'Quality Control', 'Radioimmunoassay', 'Scintillation Counting'] | 7,438,438 | [['D27.720.470.280'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['J01.897.608'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['E05.799.700']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Racial disparities in treatment for pancreatic cancer and impact on survival: a population-based analysis. | PURPOSE: Pancreatic adenocarcinoma is the fourth leading cause of cancer-related deaths in both men and women. Mortality from pancreatic cancer is higher amongst blacks compared to other races. We performed this analysis with the aim of examining racial disparity for receipt pancreatic cancer treatment and its associat... | ['Adult', 'African Americans', 'Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'European Continental Ancestry Group', 'Female', 'Health Status Disparities', 'Healthcare Disparities', 'Hispanic Americans', 'Humans', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Middle Aged', 'Pancreatic Neoplasms... | 22,246,279 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['M01.686.508.400'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['N04.590.374.380', 'N05.300.493'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Key Preoperative Clinical Factors Predicting Outcome in Surgically Treated Patients with Metastatic Epidural Spinal Cord Compression: Results from a Survey of 438 AOSpine International Members. | OBJECTIVE: Accurate prediction of surgical outcomes in patients suffering from metastatic epidural spinal cord compression (MESCC) is challenging. This survey aims to obtain expert opinion on which preoperative clinical factors are the most relevant predictors of survival, neurologic, functional, and health-related qua... | ['Attitude of Health Personnel', 'Comorbidity', 'Health Care Surveys', 'Incidence', 'Internationality', 'Neurosurgeons', 'Orthopedic Surgeons', 'Outcome Assessment, Health Care', 'Preoperative Care', 'Prognosis', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spinal Cord Compression', 'Spinal Cord Neopla... | 27,424,474 | [['F01.100.050', 'N05.300.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['I01.615'], ['M01.5... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Bladder dysfunction in Wolfram syndrome is highly prevalent and progresses to megacystis. | AIM: Wolfram syndrome is a rare genetic defect in WFS1 or WSF2(CISD2). It includes diabetes mellitus and insipidis, sensorineural deafness, optic atrophy, but not bladder dysfunction. However, this has appeared a common finding in our national referral clinic, and we sought to quantify this problem.METHODS: Data were c... | ['Adolescent', 'Child', 'Child, Preschool', 'Cohort Studies', 'Disease Progression', 'Female', 'Genotype', 'Humans', 'Male', 'Prevalence', 'Prognosis', 'Urinary Bladder', 'Urinary Bladder Diseases', 'Wolfram Syndrome', 'Young Adult'] | 29,277,467 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.656'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nonhuman primate vocalizations support categorization in very young human infants. | Language is a signature of our species and our primary conduit for conveying the contents of our minds. The power of language derives not only from the exquisite detail of the signal itself but also from its intricate link to human cognition. To acquire a language, infants must identify which signals are part of their ... | ['Age Factors', 'Animals', 'Attention', 'Child Development', 'Cognition', 'Humans', 'Infant', 'Language Development', 'Lemur', 'Species Specificity', 'Speech', 'Vocalization, Animal'] | 24,003,164 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['F02.830.104.214'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.525.200.310'], ['B01.050.150.900.649.313.988.700.508.490'], ['G16.824'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559... | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The metabolic effects of hemodialysis with and without glucose in the dialysate. | The present study compares some of the metabolic effects of hemodialysis of fasting patients with and without glucose in the dialysate bath. Unlike glucose dialysis, glucose-free dialysis caused marked decreases in blood levels of glucose, insulin, lactate, and pyruvate along with profound increases in acetoacetate and... | ['Adult', 'Aged', 'Blood Glucose', 'Female', 'Glucose', 'Humans', 'Insulin', 'Kidney Failure, Chronic', 'Lactates', 'Male', 'Middle Aged', 'Pyruvates', 'Renal Dialysis'] | 707,341 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['D02.241.511.459'], ['M01.060.116.630'], ['D02.241.75... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tamoxifen promotes differentiation of oligodendrocyte progenitors in vitro. | The most promising therapeutic approach to finding the cure for devastating demyelinating conditions is the identification of clinically safe pharmacological agents that can promote differentiation of endogenous oligodendrocyte precursor cells (OPCs). Here we show that the breast cancer medication tamoxifen (TMX), with... | ['Animals', 'Blotting, Western', 'Cell Differentiation', 'Fluorescent Antibody Technique', 'Neural Stem Cells', 'Oligodendroglia', 'Prodrugs', 'Rats', 'Tamoxifen'] | 26,820,594 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.152'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A11.872.653'], ['A08.637.600', 'A11.650.600'], ['D26.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The feature of papers and citation analysis of eleven journals in tropical medicine indexed by Science Citation Index Expanded. | To determine the features of papers, authors, and citation of eleven journals in tropical medicine indexed by Science Citation Index Expanded, the database of the Institute for Scientific Information, we analyzed original articles, editorials, reviews, corrections, letters, biographies, and news published in these jour... | ['Bibliometrics', 'Periodicals as Topic', 'Tropical Medicine'] | 16,410,973 | [['L01.178.682.099.325', 'L01.453.183.291'], ['L01.178.682.829.678'], ['H02.403.879']] | ['Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Deviant functional activation and connectivity of the right insula are associated with lack of awareness of episodic memory impairment in nonamnesic alcoholism. | A disorder of metamemory, expressed as unawareness of mnemonic ability, is typically associated with the profound amnesia of Korsakoff's Syndrome (KS). A similar but less severe type of limited awareness can also occur in non-KS alcoholism and is observed as an impairment in generating Feeling-of-Knowing (FOK) predicti... | ['Adult', 'Aged', 'Alcoholism', 'Awareness', 'Cerebral Cortex', 'Female', 'Functional Laterality', 'Functional Neuroimaging', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Memory Disorders', 'Memory, Episodic', 'Metacognition', 'Middle Aged', 'Nerve Net', 'Young Adult'] | 28,806,707 | [['M01.060.116'], ['M01.060.116.100'], ['C25.775.100.250', 'F03.900.100.350'], ['F02.463.188.150'], ['A08.186.211.200.885.287.500'], ['F02.830.297.425', 'G11.561.225.425'], ['E01.370.350.578.875', 'E01.370.376.537.625', 'E05.629.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.597.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
DELAYED POSITIVE EFFECTS OF AN ACUTE BOUT OF COORDINATIVE EXERCISE ON CHILDREN'S ATTENTION (1). | Since attention is an important prerequisite for learning, it is particularly worthwhile to promote it in schools, through specific interventions. The present study examined the effects of an acute bout of coordinative exercise in physical education on the attention of primary school children. A total of 90 fifth grade... | ['Attention', 'Child', 'Executive Function', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Physical Education and Training', 'Psychomotor Performance', 'Reaction Time', 'Time Factors'] | 26,474,438 | [['F02.830.104.214'], ['M01.060.406'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['I02.233.543'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['G01.910.857']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Obsessive-compulsive disorders in Benin: five case reports. | We report 5 cases of obsessive-compulsive disorders diagnosed among a sample of Beninese psychiatric outpatients. This type of report does not support the idea that this disorder is very rare in black Africa. Moreover, it appears that the clinical and epidemiological characteristics are not really different from those ... | ['Adult', 'African Americans', 'African Continental Ancestry Group', 'Benin', 'Cross-Cultural Comparison', 'Developing Countries', 'Follow-Up Studies', 'Humans', 'Male', 'Obsessive-Compulsive Disorder'] | 1,797,005 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['Z01.058.290.190.200'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['I01.615.500.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Synthesis and anticonvulsant activity of new 2-substituted-5- [2-(2-fluorophenoxy)phenyl]-1,3,4-oxadiazoles and 1,2,4-triazoles. | A series of new 2-substituted-5-[2-(2-fluorophenoxy)phenyl]-1,3,4-oxadiazoles has been synthesized and screened for their anticonvulsant activities. Compound 3 shows considerable anticonvulsant activity both in PTZ and MES models. It seems that this effect is mediated by benzodiazepine receptors and other unknown mecha... | ['Anticonvulsants', 'Drug Evaluation, Preclinical', 'Molecular Structure', 'Oxadiazoles', 'Structure-Activity Relationship', 'Triazoles'] | 15,546,729 | [['D27.505.954.427.080'], ['E05.290.750', 'E05.337.550'], ['G02.111.570', 'G02.466'], ['D03.383.129.462.580'], ['G02.111.830', 'G07.690.773.997'], ['D03.383.129.799']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel absolute quantitative imaging strategy of iron, copper and zinc in brain tissues by Isotope Dilution Laser Ablation ICP-MS. | Isotope Dilution Laser Ablation ICP-MS (ID-LA-ICP-MS), because of its impressive spatial resolution capacity and precise means for quantification, is one of the most promising tools for in-situ quantitative imaging of trace elements in biological samples. In the ID-LA-ICP-MS strategy for tissue section, the tissue must... | ['Animals', 'Brain Chemistry', 'Copper', 'Iron', 'Isotopes', 'Mass Spectrometry', 'Mice', 'Zinc'] | 28,843,570 | [['B01.050'], ['G02.111.150', 'G03.185'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.496'], ['E05.196.566'], ['B01.050.150.900.649.313.992.635.505.500'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of immunogenicity and safety of 2 immunizations with allantoic intranasal live influenza vaccine Ultragrivac]. | AIM: Evaluate reactogenicity, safety and immunogenicity in phase 2 clinical trials of 2 immunization schedules with Ultragrivac--an allantoic intranasal life influenza vaccine based on A/17/ duck/Potsdam/86/92 [17/H5] reassortant strain.MATERIALS AND METHODS: 4 groups of volunteers participated in the study: group 1--4... | ['Administration, Intranasal', 'Adolescent', 'Adult', 'Animals', 'Female', 'Humans', 'Immunity, Humoral', 'Immunization, Secondary', 'Influenza A Virus, H5N1 Subtype', 'Influenza A Virus, H5N2 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Middle Aged', 'Vaccines, Attenuated'] | 21,916,043 | [['E02.319.267.120.655.500'], ['M01.060.057'], ['M01.060.116'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.420'], ['E02.095.465.425.400.485', 'E05.478.550.550'], ['B04.820.480.968.405.400.500'], ['B04.820.480.968.405.400.505'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Epileptic Seizure Detection in Long-Term EEG Recordings by Using Wavelet-Based Directed Transfer Function. | GOAL: The accurate automatic detection of epileptic seizures is very important in long-term electroencephalogram (EEG) recordings. In this study, the wavelet decomposition and the directed transfer function (DTF) algorithm were combined to present a novel wavelet-based directed transfer function (WDTF) method for the p... | ['Adolescent', 'Adult', 'Algorithms', 'Brain', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Seizures', 'Wavelet Analysis', 'Young Adult'] | 29,993,489 | [['M01.060.057'], ['M01.060.116'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.742', 'C23.888.592.742'], ['E05.959', 'G17.915', 'L01.224.800.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Collaborative research under the unification model. | The research role of the clinical nurse specialist is often the most difficult to implement. At the masters level, efforts are generally directed at utilization and evaluation of research more than design and implementation. Collaboration between several investigators, however, is an efficient and effective method of p... | ['Humans', 'Models, Nursing', 'Nurse Clinicians', 'Nursing Research', 'Research Design'] | 2,030,763 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.645'], ['M01.526.485.650.648.525', 'N02.360.650.648.525'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['E05.581.500', 'H01.770.644.728']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Synaptopathy in the Aging Cochlea: Characterizing Early-Neural Deficits in Auditory Temporal Envelope Processing. | Aging listeners, even in the absence of overt hearing loss measured as changes in hearing thresholds, often experience impairments processing temporally complex sounds such as speech in noise. Recent evidence has shown that normal aging is accompanied by a progressive loss of synapses between inner hair cells and audit... | ['Acoustic Stimulation', 'Afferent Pathways', 'Aging', 'Animals', 'Auditory Threshold', 'Cochlea', 'Cochlear Nerve', 'Evoked Potentials, Auditory', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Hair Cells, Auditory, Inner', 'Hearing Loss, Sensorineural', 'Male', 'Mice', 'Mice, Inbred CBA', 'Otoacoustic Emission... | 29,976,623 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['A08.612.220'], ['G07.345.124'], ['B01.050'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['A09.246.300.246'], ['A08.800.800.120.910.120'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['G07.265.216.500.370.300', 'G07.888.250.300'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction. | BACKGROUND: Immediate reopening of the acutely occluded infarct-related artery via primary PCI is the preferred treatment in ST-elevation myocardial infarction (STEMI). However, the sudden reinitiation of blood flow can lead to a local acute inflammatory response with further endothelial and myocardial damage, so-calle... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Double-Blind Method', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Fibrin Fibrinogen Degradation Products', 'Fibrinolytic Agents', 'Humans', 'Magnetic Resonance Angiography', 'Male', 'Matrix Metalloproteinase 2', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Reperfus... | 21,727,201 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.478.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Capecitabine-induced headache responding to diltiazem. | BACKGROUND: Headaches have been reported as a potential side effect of capecitabine therapy. However, severe limiting headaches are rarely experienced in this setting and no known therapy has been described for such a serious side effect.RESULTS: We report the case of a patient treated with capecitabine and radiation f... | ['Adult', 'Antimetabolites, Antineoplastic', 'Capecitabine', 'Deoxycytidine', 'Diltiazem', 'Female', 'Fluorouracil', 'Headache', 'Humans', 'Rectal Neoplasms'] | 17,536,204 | [['M01.060.116'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], ['D03.633.100.079.150'], ['D03.383.742.698.875... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Significant impact of the MTHFR polymorphisms and haplotypes on male infertility risk. | BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) converts 5,10-methylene tetrahydrofolate to 5-methyl tetrahydrofolate and affects the activity of cellular cycles participating in nucleotide synthesis, DNA repair, genome stability, maintenance of methyl pool, and gene regulation. Genetically compromised MTHFR ac... | ['Case-Control Studies', 'Genetic Predisposition to Disease', 'Haplotypes', 'Humans', 'Infertility, Male', 'Linkage Disequilibrium', 'Male', 'Methylenetetrahydrofolate Reductase (NADPH2)', 'Odds Ratio', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Polymorphism, Single Nucleotide', 'Sequenc... | 23,874,907 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['G05.348.500'], ['D08.811.682.662.290', 'D12.776.331.775'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Kinetics of micronucleus expression in synchronized irradiated Chinese hamster ovary cells. | The kinetics of expression of radiation-induced micronuclei (MN) in synchronized Chinese hamster cells (CHO) was examined. The purpose of the study was to determine if the cell cycle distribution of a population significantly influences the levels of radiation induced MN, thereby obscuring the exact quantification of t... | ['Animals', 'Cell Cycle', 'Cell Nucleus', 'Cells, Cultured', 'Chromosome Aberrations', 'Cricetinae', 'Cricetulus', 'DNA', 'Dose-Response Relationship, Radiation', 'Female', 'Interphase', 'Kinetics', 'Ovary'] | 3,986,869 | [['B01.050'], ['G04.144'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D13.444.308'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monoclonal antibodies that inhibit mitogenic activity of Mycoplasma pulmonis. | Previous studies have suggested a correlation between mitogenic, polyclonal activation of host lymphocytes and the respiratory tract inflammatory diseases induced by Mycoplasma pulmonis. This study describes the generation of monoclonal antibodies (MAbs) to M. pulmonis membrane antigens with different capacities to inh... | ['Animals', 'Antibodies, Bacterial', 'Antibodies, Monoclonal', 'Antigens, Bacterial', 'Blotting, Western', 'Cell Division', 'Female', 'Hybridomas', 'Lymphocyte Activation', 'Membranes', 'Mitogens', 'Mycoplasma', 'Rats', 'Species Specificity'] | 7,806,349 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.161'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of total body and visceral fat mass with iron deficiency in preadolescents: the Healthy Growth Study. | The aim of the present study was to examine the associations of obesity, percentage body fat and visceral fat mass with body Fe status in a representative sample of 1493 schoolchildren aged 9-13 years. Anthropometric, body composition, biochemical, clinical (Tanner stage, age of menarche) and dietary intake data were c... | ['Adipose Tissue', 'Adolescent', 'Adolescent Development', 'Anemia, Iron-Deficiency', 'Body Composition', 'Child', 'Child Development', 'Cross-Sectional Studies', 'Diet', 'Female', 'Greece', 'Humans', 'Intra-Abdominal Fat', 'Iron', 'Iron, Dietary', 'Male', 'Obesity', 'Obesity, Abdominal', 'Prevalence', 'Sex Factors'] | 22,088,365 | [['A10.165.114'], ['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['C15.378.071.196.300', 'C18.452.565.100'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['Z01.542... | ['Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cardiac pacemakers in absence of the SA node: responses to exercise and autonomic blockade. | Surgical excision of the sinoatrial node, verified histologically, is followed by a supraventricular (atrial) rhythm in both resting and exercising dog whether anesthetized or conscious. The ECG is characterized by a definitive P wave and associated atrial electrograms. Waxing and waning in heart rate, generally referr... | ['Adrenergic beta-Antagonists', 'Animals', 'Autonomic Nervous System', 'Dogs', 'Heart', 'Heart Conduction System', 'Heart Rate', 'Physical Exertion', 'Sinoatrial Node'] | 25,585 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['A08.800.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['A07.541.409'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G11.427.683'], ['A07.541.409.819']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of microRNA-based signatures for response and survival for non-small cell lung cancer treated with cisplatin-vinorelbine A ELCWP prospective study. | UNLABELLED: Clinical variables, like stage and performance status (PS), have predictive and prognostic values in advanced non-small cell lung cancer (NSCLC) patients treated with chemotherapy, not allowing adequate individual prediction. MicroRNA (miRNA) are non-coding RNAs regulating gene expression. In a prospective ... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Non-Small-Cell Lung', 'Cisplatin', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'MicroRNAs', 'Middle Aged', 'Prospective Studies', 'Transcriptome', 'Treatment Outcome', 'Vinblastine', 'Vinorelbine'] | 24,007,627 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cholic Acid-Peptide Conjugates as Potent Antimicrobials against Interkingdom Polymicrobial Biofilms. | Interkingdom polymicrobial biofilms formed by Gram-positive Staphylococcus aureus and Candida albicans pose serious threats of chronic systemic infections due to the absence of any common therapeutic target for their elimination. Herein, we present the structure-activity relationship (SAR) of membrane-targeting cholic ... | ['Animals', 'Anti-Infective Agents', 'Biofilms', 'Candida albicans', 'Candidiasis', 'Cholic Acid', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Microbial Sensitivity Tests', 'Microbial Viability', 'Peptides', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 31,427,303 | [['B01.050'], ['D27.505.954.122'], ['A20.593', 'G06.120'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160'], ['D04.210.500.105.225.130', 'D04.210.500.221.430.130'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin. | The myogenic basic helix-loop-helix transcription factors, Myf5, MyoD, myogenin and MRF4, play key roles in skeletal muscle development. All of them induce myogenic differentiation in cultured non-muscle cells, suggesting that they might be functionally redundant. But the genes are expressed at different times during e... | ['Animals', 'Base Sequence', 'Cell Line', 'DNA Primers', 'DNA, Complementary', 'DNA-Binding Proteins', 'Helix-Loop-Helix Motifs', 'Mice', 'Molecular Sequence Data', 'Muscle Proteins', 'Myogenic Regulatory Factor 5', 'Myogenin', 'Ribs', 'Trans-Activators', 'Transcription Factors'] | 8,587,605 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.260'], ['G02.111.570.820.709.275.500.360'], ['B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Major hemorrhage from pseudocysts and pseudoaneurysms caused by chronic pancreatitis: surgical therapy. | Acute hemorrhage from pseudocysts and pseudoaneurysms is the most rapidly lethal complication of chronic pancreatitis. Diagnostic procedures and therapy are still a subject of controversy. We report our experience with 10 patients operated on during the past 10 years. Of these patients, 5 had acute gastrointestinal hem... | ['Adult', 'Aneurysm', 'Chronic Disease', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Male', 'Middle Aged', 'Pancreatectomy', 'Pancreatic Diseases', 'Pancreatic Pseudocyst', 'Pancreatitis'] | 1,949,866 | [['M01.060.116'], ['C14.907.055'], ['C23.550.291.500'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.210.752'], ['C06.689'], ['C04.182.640.692', 'C06.689.500.692'], ['C06.689.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Institutionalization of programs in medical education. | Through the use of questionnaires and interview schedules during extended site visits, sixteen programs training residents in non-family medicine primary care were studied to determine what factors contributed to program success -- known as "institutionalization" -- or to program failure. The findings revealed that pro... | ['Internship and Residency', 'Primary Health Care', 'Training Support', 'United States'] | 10,252,779 | [['I02.358.337.350.500', 'I02.358.399.350.750'], ['N04.590.233.727'], ['N03.219.483.838'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
The coming acceleration of global population ageing. | The future paths of population ageing result from specific combinations of declining fertility and increasing life expectancies in different parts of the world. Here we measure the speed of population ageing by using conventional measures and new ones that take changes in longevity into account for the world as a whole... | ['Age Distribution', 'Aged', 'Aged, 80 and over', 'Aging', 'Emigration and Immigration', 'Geography', 'Humans', 'Internationality', 'Life Expectancy', 'Longevity', 'Middle Aged', 'Mortality', 'Population Density', 'Time Factors'] | 18,204,438 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615'], ['E05.318.308.985.450', 'N01.224.935.464', ... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Grammar in Boys With Idiopathic Autism Spectrum Disorder and Boys With Fragile X Syndrome Plus Autism Spectrum Disorder. | Purpose: Some boys with autism spectrum disorder (ASD) and boys with fragile X syndrome and a codiagnosis of ASD (FXS+ASD) have impairments in expressive grammatical abilities. The current study compared grammatical performance in these 2 groups of school-age boys.Method: Thirty-seven boys similar on mean length of utt... | ['Adolescent', 'Autism Spectrum Disorder', 'Child', 'Fragile X Syndrome', 'Humans', 'Intelligence', 'Language Tests', 'Linguistics', 'Male'] | 29,541,769 | [['M01.060.057'], ['F03.625.164.113'], ['M01.060.406'], ['C10.597.606.360.455.500', 'C16.131.260.830.300', 'C16.320.180.830.300', 'C16.320.322.500.500', 'C16.320.400.525.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['F04.711.513.240'], ['L01.559.598']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Cellular uptake of Aib-containing amphipathic helix peptide. | Cell-penetrating peptides (CPPs) are useful tools for the delivery of hydrophilic bioactive molecules, such as peptides, proteins, and oligonucleotides, across the cell membrane. To realize the delivery of therapeutic macromolecules by CPPs, the CPPs are required to show resistance to protease and no cytotoxicity. In o... | ['Aminoisobutyric Acids', 'Cell Line, Tumor', 'Cell Membrane', 'Cell-Penetrating Peptides', 'Drug Design', 'Drug Discovery', 'Drug Evaluation, Preclinical', 'Epithelial Cells', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Macromolecular Substances', 'Molecular Structure', 'Peptides', 'Pronase', 'Protein Struc... | 21,875,799 | [['D02.241.081.114.968.249', 'D12.125.070.075', 'D12.125.190.055'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.149'], ['D12.644.098'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['E05.290.750', 'E05.337.550'], ['A11.436'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Parasites of domestic and wild animals in South Africa. XXIII. Helminth and arthropod parasites of warthogs, Phacochoerus aethiopicus, in the eastern Transvaal Lowveld. | A total of 69 warthogs, Phacochoerus aethiopicus, were collected from 4 localities within the Kruger National Park, eastern Transvaal Lowveld. These animals harboured 16 nematode species, 2 trematodes, 1 or 2 species of adult cestodes and the larval stages of 4 cestodes. No pattern of seasonal abundance could be determ... | ['Animals', 'Animals, Wild', 'Arthropods', 'Helminths', 'Seasons', 'South Africa', 'Swine'] | 3,194,114 | [['B01.050'], ['B01.050.050.300'], ['B01.050.500.131'], ['B01.050.500.500'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['Z01.058.290.175.735'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The intergenerational transference of alcohol use behaviour from parents to offspring: a test of the cognitive model. | The current study tested the model proposed by Campbell and Oei (2010), and assessed the separate components of the model to best explain the intergenerational transference of alcohol use behaviour. Results revealed an adequate fit of all three models with significant differences between the Cognitive and Behavioral Mo... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Age Factors', 'Alcohol Drinking', 'Alcoholism', 'Cognition', 'Family', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Theoretical', 'Parent-Child Relations', 'Parents', 'Risk Factors', 'Surveys and Questionnaires', 'Transference, Psychology'] | 20,219,287 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['F02.463.188'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599'], ['F01.829.263.370.290'], ['F01.829.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
RMTL: an R library for multi-task learning. | MOTIVATION: Multi-task learning (MTL) is a machine learning technique for simultaneous learning of multiple related classification or regression tasks. Despite its increasing popularity, MTL algorithms are currently not available in the widely used software environment R, creating a bottleneck for their application in ... | ['Algorithms', 'Databases, Genetic', 'Machine Learning', 'Software'] | 30,256,897 | [['G17.035', 'L01.224.050'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G17.035.250.500', 'L01.224.050.375.530'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of dissolved oxygen and carbon-nitrogen loads on denitrification by an aerobic consortium. | Four samples of natural ecosystems and one sample from an activated sludge treatment plant were mixed together and progressively adapted to alternating aerobic/anoxic phases in the presence of nitrate in order to enrich the microflora in aerobic denitrifiers. Aerobic denitrifying performances of this mixed ecosystem at... | ['Aerobiosis', 'Biomass', 'Nitrogen', 'Oxygen', 'Sewage'] | 11,092,629 | [['G02.111.017', 'G03.049'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D01.268.604', 'D01.362.625'], ['D01.268.185.550', 'D01.362.670'], ['D20.944.932.500']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anxiety sensitivity and nonclinical panic attacks. | The present study examined anxiety sensitivity in relation to trait anxiety and the occurrence of nonclinical panic attacks in 265 subjects. Fifty percent of high anxiety sensitivity subjects reported panic attacks (both cued and spontaneous) in the past year. In addition, almost 42% of subjects with high anxiety sensi... | ['Adult', 'Anxiety', 'Arousal', 'Association Learning', 'Female', 'Humans', 'Male', 'Panic', 'Personality Inventory', 'Set, Psychology', 'Social Environment'] | 1,888,327 | [['M01.060.116'], ['F01.470.132'], ['F02.830.104', 'G11.561.035'], ['F02.463.425.069.296'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.361.585'], ['F04.711.647.513'], ['F02.463.425.838'], ['I01.880.853.500']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Adhesion and activation of platelets and polymorphonuclear granulocyte cells at TiO2 surfaces. | The initial reactions of two TiO2 surfaces with blood were investigated by short-time exposure to capillary blood and analysis of surface-adsorbed plasma proteins and surface-adhering cells by using immunofluorescence techniques. Antibodies directed against platelet membrane antigen and P-selectin were used to visualiz... | ['Biocompatible Materials', 'Biomarkers', 'Blood Coagulation Factors', 'Blood Platelets', 'Cell Adhesion', 'Humans', 'Image Processing, Computer-Assisted', 'Macrophage-1 Antigen', 'Microscopy, Electron, Scanning', 'Neutrophils', 'P-Selectin', 'Surface Properties', 'Titanium'] | 9,011,589 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D23.101'], ['D12.776.124.125', 'D23.119'], ['A11.118.188', 'A15.145.229.188'], ['G04.022'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['D12.776.543.750.705.408.495.500', 'D12.776.543.750.705.408.600.500', 'D12.776.543.750.705.833.500'], ['E01... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Failure mechanisms of ventricular tissue due to deep penetration. | Lead perforation is a rare but serious complication of pacemaker implantations, and in the present study the associated tissue failure was investigated by means of in-vitro penetration of porcine and bovine ventricular tissue. Rectangular patches from the right ventricular free wall and the interventricular septum were... | ['Animals', 'Cattle', 'Elasticity', 'Heart Ventricles', 'Medical Laboratory Science', 'Microscopy, Electron, Scanning', 'Swine'] | 19,200,998 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.374.590'], ['A07.541.560'], ['H02.010.450', 'J01.897.480'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Urodynamics rationale. The flow curve]. | OBJECTIVE: To describe the mathematical representation of a common phenomenon: the urinary flow curve.METHODS: The statistical adjustment for minimum squares was the method employed in the study.RESULTS: A mathematical expression was obtained with a goodness of fit for each flow curve and an acceptable margin of error.... | ['Humans', 'Mathematics', 'Urodynamics'] | 10,802,919 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['G08.852.898']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of open water on the performance of a constructed wetland for nonpoint source pollution control. | The seasonal performance of four differently configured constructed wetland systems was compared for the treatment efficiency of nonpoint source pollution. Dead plants in the constructed wetlands increased the nitrogen removal rate during winter by providing organic carbon, which is essential for the denitrification pr... | ['Waste Disposal, Fluid', 'Water', 'Water Microbiology', 'Water Pollutants', 'Water Pollution', 'Water Purification', 'Water Supply', 'Wetlands'] | 20,818,039 | [['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['D27.888.284.903'], ['N06.850.460.790'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900'], ['J01.293.821.500'], ['G16.500.275... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Inflammatory mediators in uveitis: differential induction of cytokines and chemokines in Th1- versus Th2-mediated ocular inflammation. | Ocular inflammation leads to vision loss through the destruction and scarring of delicate tissues along the visual axis. To identify inflammatory mediators involved in this process, we used real time RT-PCR to quantify the expression of mRNA transcripts of 34 cytokines, 26 chemokines, and 14 chemokine receptors at cert... | ['Adoptive Transfer', 'Animals', 'Autoimmune Diseases', 'Cell Movement', 'Chemokines', 'Cytokines', 'Kinetics', 'Mice', 'Mice, Transgenic', 'Muramidase', 'Pigment Epithelium of Eye', 'RNA, Messenger', 'Th1 Cells', 'Th2 Cells', 'Transcriptional Activation', 'Uveitis'] | 11,859,142 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['C20.111'], ['G04.198', 'G07.568.500.180'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP). | BACKGROUND: Recurrent venous thromboembolism (VTE) is common. Current guidelines suggest that patients with unprovoked VTE should continue anticoagulants unless they have a high bleeding risk, whereas all others can stop. Prediction models may refine this dichotomous distinction, but existing models apply only to patie... | ['Adolescent', 'Adult', 'Aged', 'Algorithms', 'Anticoagulants', 'Case-Control Studies', 'Female', 'Follow-Up Studies', 'Hemorrhage', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Netherlands', 'Norway', 'Polymorphism, Single Nucleotide', 'Probability', 'Prognosis', 'Recurrence', 'Risk Assessment', 'Risk Fa... | 31,603,898 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['D27.505.954.502.119'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.414'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Polymorphisms in the PON gene cluster are associated with Alzheimer disease. | Paraoxonase is an arylesterase enzyme that is expressed in the liver and found in the circulation in association with apoA1 and the high-density lipoprotein, and prevents the accumulation of oxidized lipids in low-density lipoproteins in vitro. Common polymorphisms in genes encoding paraoxonase are established risk fac... | ['African Americans', 'Alzheimer Disease', 'Aryldialkylphosphatase', 'European Continental Ancestry Group', 'Gene Frequency', 'Humans', 'Linkage Disequilibrium', 'Multigene Family', 'Polymorphism, Single Nucleotide', 'Promoter Regions, Genetic', 'United States'] | 16,319,130 | [['M01.686.508.100.100', 'M01.686.754.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D08.811.277.352.660.500'], ['M01.686.508.400'], ['G05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.500'], ['G05.360.340.024.340.645'], ['G05.365.795.598'], ['G02.111.570.080.689.675', 'G05.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Renal tubular damage after renal stone treatment. | 50 patients were studied with respect to renal tubular damage related to open operative, percutaneous and extracorporeal shock wave treatment of renal stones. Preoperative and postoperative urinary N-acetyl-glucosaminidase (NAG) levels were measured as a marker of renal damage. There was no significant evidence of rena... | ['Acetylglucosaminidase', 'Creatine Kinase', 'Humans', 'Isoenzymes', 'Kidney Calculi', 'Kidney Tubules', 'L-Lactate Dehydrogenase', 'Lithotripsy'] | 3,368,997 | [['D08.811.277.450.483.180.500'], ['D08.811.913.696.640.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. | Although mechanisms for chromosomal instability in tumors have been described in animal and in vitro models, little is known about these processes in man. To explore cytogenetic evolution in human tumors, chromosomal breakpoint profiles were constructed for 102 pancreatic carcinomas and 140 osteosarcomas, two tumor typ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cell Survival', 'Chromosome Aberrations', 'DNA Fragmentation', 'Female', 'Humans', 'Interphase', 'Male', 'Middle Aged', 'Neoplasms', 'Repetitive Sequences, Nucleic Acid', 'Telomerase', 'Telomere'] | 11,675,499 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G04.346'], ['C23.550.210', 'G05.365.590.175'], ['G05.200.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.144.500'], ['M01.060.116.630'], ['C04'], ['G02.111.570.080.708', 'G05.360.080.708'], ['D08.811.913.696.445.308.300.750... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Host suppression of quorum sensing during catheter-associated urinary tract infections. | Chronic bacterial infections on medical devices, including catheter-associated urinary tract infections (CAUTI), are associated with bacterial biofilm communities that are refractory to antibiotic therapy and resistant to host immunity. Previously, we have shown that Pseudomonas aeruginosa can cause CAUTI by forming a ... | ['Acyl-Butyrolactones', 'Animals', 'Catheter-Related Infections', 'DNA, Bacterial', 'Gene Expression Regulation, Bacterial', 'Host-Pathogen Interactions', 'Humans', 'Mice', 'Phenotype', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Quorum Sensing', 'Sequence Analysis, RNA', 'Urea', 'Urinary Tract Infections'] | 30,361,690 | [['D02.540.232'], ['B01.050'], ['C01.195'], ['D13.444.308.212'], ['G05.308.300'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.695'], ['C01.150.252.400.739'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['G04.085.700', 'G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using polymer chemistry to modulate the delivery of neurotrophic factors from degradable microspheres: delivery of BDNF. | PURPOSE: Brain-derived neurotrophic factor (BDNF) plays an important role in neuroprotection and repair, but long-term delivery from polymer systems has been challenging. We investigated the role the chemistry of the polymer played in loading and delivery of BDNF via microspheres, which are suitable for minimally invas... | ['Animals', 'Brain-Derived Neurotrophic Factor', 'Cell Differentiation', 'Chemistry, Pharmaceutical', 'Drug Carriers', 'Lactic Acid', 'Microspheres', 'Models, Chemical', 'PC12 Cells', 'Particle Size', 'Polyethylene Glycols', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Polylysine', 'Polymers', '... | 19,921,405 | [['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G04.152'], ['H01.158.703.007', 'H01.181.466'], ['D26.255.260', 'E02.319.300.380'], ['D02.241.511.459.450'], ['E07.565'], ['E05.599.495'], ['A11.251.210.190.750', 'A11.251.860.180.750', 'A11.299.500'], ['G02.712'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Measles epidemics and seroepidemiology of population in Wujin, Changzhou city, Jiangsu province, China 2015. | The measles epidemic was rather severe in Wujin 2015, and a seroprevalence survey of measles antibody was conducted during June to September 2015 in Wjin district of Changzhou city. Blood samples were collected from community health population and convenient samples of residual blood from hospitals. Measles-specific Ig... | ['Adolescent', 'Adult', 'Antibodies, Viral', 'Child', 'Child, Preschool', 'China', 'Enzyme-Linked Immunosorbent Assay', 'Epidemics', 'Female', 'Humans', 'Incidence', 'Infant', 'Male', 'Measles', 'Measles Vaccine', 'Measles virus', 'Middle Aged', 'Population Surveillance', 'Seroepidemiologic Studies', 'Serologic Tests',... | 28,433,329 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['N06.850.290.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fluoride-induced fractures: relation to osteogenic effect. | The possible effects of fluoride in inducing fractures were studied in 61 patients treated with sodium fluoride (NaF), 40-60 mg daily in combination with calcium and vitamin D. Nine patients developed the fluoride-(F) related lower extremity pain syndrome. Four other patients had stress fractures associated with trauma... | ['Aged', 'Drug Therapy, Combination', 'Female', 'Femoral Neck Fractures', 'Fractures, Bone', 'Fractures, Stress', 'Humans', 'Leg', 'Middle Aged', 'Osteogenesis', 'Osteoporosis, Postmenopausal', 'Pain', 'Radionuclide Imaging', 'Retrospective Studies', 'Sodium Fluoride', 'Syndrome', 'Vitamin D'] | 2,339,632 | [['M01.060.116.100'], ['E02.319.310'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['C26.404'], ['C26.404.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['C05.116.198.579.610', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Evaluation of fitness levels of children with a diagnosis of acute leukemia and lymphoma after completion of chemotherapy and autologous hematopoietic stem cell transplantation. | The aim of this study was to assess the fitness levels and possible deficits in physical performance in children with a diagnosis of childhood acute leukemia and lymphoma after 10 months of therapy ending through a specific test battery. A total of 58 subjects were enrolled in this study. The experimental group (EG) (7... | ['Acute Disease', 'Case-Control Studies', 'Child', 'Exercise Test', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Leukemia', 'Lymphoma', 'Male', 'Physical Fitness', 'Transplantation Conditioning', 'Transplantation, Autologous'] | 24,520,088 | [['C23.550.291.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['C04.557.386', 'C15.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Myoepithelioma of minor salivary gland origin. Light and electron microscopical study. | A gingival tumor that invaded the anterior maxilla was removed from a 14-year-old boy and studied by light and electron microscopy. The tumor was composed exclusively of myoepithelial cells and appeared to be malignant. By light microscopy, the tumor appeared to be a poorly differentiated epithelial neoplasm of undeter... | ['Adolescent', 'Biopsy', 'Cell Nucleus', 'Chromatin', 'Cobalt Radioisotopes', 'Diagnosis, Differential', 'Gingiva', 'Gingival Neoplasms', 'Glycogen', 'Humans', 'Male', 'Maxilla', 'Maxillary Neoplasms', 'Microscopy', 'Microscopy, Electron', 'Myoepithelioma', 'Radiography', 'Salivary Gland Neoplasms', 'Staining and Label... | 48,374 | [['M01.060.057'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D01.268.556.185.500.354', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The effectiveness of hygiene procedures for prevention of cross-contamination from chicken carcases in the domestic kitchen. | Thirteen sites in each of 60 domestic kitchens were examined for Salmonella and Campylobacter spp. following the preparation of a chicken for cooking and the application of different hygiene regimes. During food preparation bacteria became widely disseminated to hand and food contact surfaces. Where cleaning was carrie... | ['Animals', 'Campylobacter', 'Chickens', 'Cooking', 'Cooking and Eating Utensils', 'Disinfection', 'Food Handling', 'Hypochlorous Acid', 'Meat', 'Salmonella'] | 10,664,978 | [['B01.050'], ['B03.440.180', 'B03.660.150.235.250.500'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['J01.576.423.200.200'], ['J01.494.300', 'J01.576.423.200.300', 'J01.637.370'], ['N06.850.780.200.450.850.375'], ['J01.576.423.200'], ['D01.029.260.365', 'D01.210.465', 'D01.339.431.311', 'D01.650.5... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Anti-allergic activity of roxithromycin: inhibition of interleukin-5 production from mouse T lymphocytes. | This study was designed to evaluate the effects of roxithromycin (RXM), a newly synthesized macrolide antibiotic on allergic responses in mice. RXM was orally administered into BALB/c mice once a day for 42 days in a single dose of 5 mg/kg body weight. Spleen cells (Sp C) collected from mice on day 7, 14, 28 and 42 pos... | ['Animals', 'Cytokines', 'Interleukin-5', 'Lymphocyte Activation', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Roxithromycin', 'Spleen', 'T-Lymphocytes'] | 8,421,430 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.644.276.374.465.202', 'D12.776.467.374.465.186', 'D23.529.374.465.202'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Nephropathies with HBsAg deposition in the kidneys]. | Among the 646 kidney biopsies HBsAg deposition in the kidney was found in 14 cases. The clinical course of nephropathy was determined by the morphological variant of the affection. No parallelism was found between HBsAg discovery in the blood and kidney biopsy specimens. HBsAg can be a risk factor for nephropathy devel... | ['Adolescent', 'Adult', 'Chronic Disease', 'Female', 'Glomerulonephritis, Membranoproliferative', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Humans', 'Kidney Glomerulus', 'Kidney Tubules', 'Male', 'Middle Aged', 'Nephritis, Interstitial'] | 2,724,892 | [['M01.060.057'], ['M01.060.116'], ['C23.550.291.500'], ['C12.777.419.570.363.615', 'C13.351.968.419.570.363.615', 'C20.425'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D23.050.327.495.500.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.324.359', 'A05.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Imaging the effects of propofol on human cerebral glucose metabolism using positron emission tomography. | The effects of propofol on glucose metabolism in different cerebral regions were observed, using positron emission tomography (PET) technology, to determine a possible cerebral target region. Seven healthy volunteers were injected with (18)F-fluorodeoxyglucose developing agent for PET scanning whilst awake (control gro... | ['Adult', 'Anesthetics, Intravenous', 'Brain', 'Brain Mapping', 'Female', 'Fluorodeoxyglucose F18', 'Glucose', 'Humans', 'Male', 'Positron-Emission Tomography', 'Propofol', 'Radiopharmaceuticals'] | 19,094,440 | [['M01.060.116'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D09.254.229.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.350.800.700', 'E01.370.350.600.35... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Studies of coexisting honeybee and vespid-venom sensitivity. | Honeybee and vespid venom-specific IgE were measured by RAST in randomly selected sera of 87 patients who had had anaphylactic reactions after insect stings. Overall there was a poor correlation between the titers of honeybee venom and yellow jacket or hornet venom-specific IgE. Sera from nine patients with high titers... | ['Adolescent', 'Adult', 'Aged', 'Bee Venoms', 'Cross Reactions', 'Desensitization, Immunologic', 'Humans', 'Hypersensitivity', 'Immune Sera', 'Immunoglobulin E', 'Male', 'Middle Aged', 'Radioallergosorbent Test', 'Wasp Venoms'] | 6,699,307 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D20.888.065.115', 'D23.946.833.065.115'], ['G12.122.281'], ['E02.095.465.425.450.310', 'E05.478.610.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.77... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is blood transfusion necessary in all patients with disseminated intravascular coagulation associated postpartum hemorrhage? | OBJECTIVE: The diagnosis of disseminated intravascular coagulation (DIC) in obstetrics is complicated owing to physiological changes, particularly during late pregnancy and the postpartum period. Therefore, a pregnancy-modified DIC score that includes only three components of the International Society on Thrombosis and... | ['Blood Transfusion', 'Case-Control Studies', 'Decision Support Techniques', 'Disseminated Intravascular Coagulation', 'Female', 'Fibrinogen', 'Humans', 'Platelet Count', 'Postpartum Hemorrhage', 'Pregnancy', 'Prothrombin Time', 'Retrospective Studies', 'Turkey'] | 29,065,752 | [['E02.095.135'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.245', 'L01.313.500.750.190'], ['C15.378.100.220', 'C15.378.463.250', 'C15.378.925.220'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Financial techniques for evaluating equipment acquisitions. | The author explains various financial techniques that can be used to evaluate equipment acquisitions. She also introduces the concept of the time value of money and explains how incorporating this concept into the analysis can provide nurse executives with a better perspective of the factors involved in committing orga... | ['Budgets', 'Capital Financing', 'Cost-Benefit Analysis', 'Decision Making, Organizational', 'Equipment and Supplies', 'Humans', 'Leasing, Property', 'Nurse Administrators'] | 1,900,326 | [['N03.219.463.060'], ['N03.219.463.085'], ['N03.219.151.125'], ['N04.452.190'], ['E07'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.463.500'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thyrotropin binding inhibiting immunoglobulins (TBII) in Graves' disease, toxic nodular goitre and autoimmune thyroiditis. | The occurrence of thyrotropin binding inhibiting immunoglobulins (TBII) was studied in 144 patients with different types and stages of Graves' disease (GD) including 2 patients with primary hypothyroidism which changed into hyperthyroid GD. TBII were also studied in 17 patients with toxic nodular goitre (TNG) and 29 pa... | ['Adolescent', 'Adult', 'Aged', 'Antithyroid Agents', 'Autoimmune Diseases', 'Female', 'Goiter, Nodular', 'Graves Disease', 'Humans', 'Hypothyroidism', 'Immunoglobulin G', 'Immunoglobulins, Thyroid-Stimulating', 'Male', 'Middle Aged', 'Thyroiditis', 'Thyroiditis, Autoimmune'] | 6,184,007 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D06.347.100', 'D27.505.696.399.450.100'], ['C20.111'], ['C19.874.283.501'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['D12.776.124.486.485.114.619.393', 'D12.776.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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