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Familial interstitial nephritis. | We report a family in whom sixteen members in three consecutive generations have died or currently suffer from chronic renal failure. Histology revealed an interstitial nephritis. One patient also had medullary cysts. The condition appears to be similar to familial juvenile nephronophthisis. | ['Adult', 'Biopsy', 'Female', 'Humans', 'Kidney', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Nephritis, Interstitial', 'Pedigree', 'Polycystic Kidney Diseases'] | 1,009,697 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['C12.777.41... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Identification of the nucleotide sequences specific for the 5'-flanking regions of the genes regulated by glucocorticoids by a computer analysis method]. | Nucleotide sequences of 5'-flanking regions of 11 glucocorticoid-regulated genes and 14 genes non-regulated by these hormones were studied using context computer analysis. Consensus TGTTCT, previously found in DNA fragments protected by glucocorticoid-receptor complexes from DNAase I digestion, was shown to be nonspeci... | ['Animals', 'Base Sequence', 'Binding Sites', 'Cattle', 'Computers', 'Cytosine', 'DNA', 'DNA, Viral', 'Genes', 'Glucocorticoids', 'Humans', 'Male', 'Mammary Tumor Virus, Mouse', 'Mice', 'Rabbits', 'Rats', 'Receptors, Glucocorticoid'] | 3,008,884 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['B01.050.150.900.649.313.500.380.271'], ['L01.224.230.260'], ['D03.383.742.698.421'], ['D13.444.308'], ['D13.444.308.568'], ['G05.360.340.024.340'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.98... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hybrid volumetric modulated arc therapy for chest wall irradiation: For a good plan, get the right mixture. | PURPOSE: To find the optimal dose weighting for hybrid volumetric modulated arc therapy (H-VMAT), a combination of conventional 3DCRT and VMAT plans for left sided chest wall and supraclavicular radiation therapy.METHODS & MATERIALS: 20 left-sided breast cancer patients who received adjuvant radiotherapy were considere... | ['Humans', 'Organs at Risk', 'Proton Therapy', 'Radiometry', 'Radiotherapy Dosage', 'Radiotherapy, Intensity-Modulated', 'Respiration', 'Respiratory-Gated Imaging Techniques', 'Retrospective Studies', 'Thoracic Wall', 'Tomography, X-Ray Computed', 'Unilateral Breast Neoplasms'] | 30,139,614 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.635'], ['E02.815.250.500'], ['E05.799'], ['E02.815.639'], ['E02.815.635.700.700', 'L01.313.500.750.100.710.600.550.700'], ['G09.772.705'], ['E01.370.350.730', 'E01.370.386.730'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500',... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Using willingness to pay to measure family members' preferences in mental health. | BACKGROUND: Willingness to pay is a valuation technique that has rarely been applied in mental health economics. First used in environmental economics to measure the intangible value of environmental improvements, WTP has increasingly been used in health care economics. The technique may be useful in mental health poli... | ['Consumer Behavior', 'Cost-Benefit Analysis', 'Data Collection', 'Family', 'Financing, Personal', 'Humans', 'Mental Disorders', 'Mental Health Services', 'Patient Admission', 'United States'] | 15,998,979 | [['F01.145.236'], ['N03.219.151.125'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.829.263', 'I01.880.853.150'], ['N03.219.559'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F04.408', 'N02.421.461'], ['E02.760.400.600', 'N02.421.585.400.600'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Analgesic nephropathy: clinical syndrome and prognosis. | Over a five-year period 86 patients presented to a renal unit with a history of prolonged analgesic abuse and no other obvious cause of renal damage. Anaemia and peptic ulceration were common, and neurological states suggestive of chronic analgesic intoxication occurred in 22 patients. Thirty-two patients died during f... | ['Acetaminophen', 'Adult', 'Aged', 'Anemia', 'Aspirin', 'Humans'] | 5,101,354 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.116'], ['M01.060.116.100'], ['C15.378.071'], ['D02.455.426.559.389.657.410.595.176'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Steady increment of immature platelet fraction is suppressed by irradiation in single-donor platelet components during storage. | Circulating immature platelet fraction (IPF) reflects real-time thrombopoiesis and correlates with platelet recovery from thrombocytopenic presentations. To understand the dynamics of IPF in platelet transfusions, we quantified the %-IPF in single-donor platelet components (SDP) during prolonged storage. %-IPF signific... | ['Blood Platelets', 'Cell Proliferation', 'Cells, Cultured', 'Gamma Rays', 'Humans', 'Microscopy, Electron, Transmission', 'Platelet Count', 'Platelet Transfusion', 'Temperature', 'Thrombocytopenia', 'Thrombopoiesis', 'Time Factors'] | 24,416,412 | [['A11.118.188', 'A15.145.229.188'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.22... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Rheumatoid arthritis among the rural population of southern Bulgaria (transitory morbidity established using the Rome and New York diagnostic criteria)]. | Examinations of 5021 subjects (2779 females and 2242 males) were carried out with a view to rheumatoid arthritis. En masse examinations of the population over the age of 20 were carried out in eight villages of South Bulgaria. Making use of the Roman diagnostic criteria, rheumatoid arthritis--probable form, was found i... | ['Adult', 'Age Factors', 'Aged', 'Arthritis, Rheumatoid', 'Bulgaria', 'Female', 'Humans', 'Male', 'Middle Aged', 'New York City', 'Rome', 'Rural Population', 'Sex Factors'] | 898,925 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['Z01.542.248.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', 'Z01.433.741'], [... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Type IV collagen immunostaining is a simple, reliable diagnostic tool for distinguishing between adenomatous and normal pituitary glands. | CONTEXT: Pituitary adenomas are clinically diagnosed based on radiologic studies and/or secondary effects of hormone production. Definitive pathologic identification relies on immunohistochemical detection of a clonal population of hormone-producing cells. However, not all adenomas secrete hormones, so performing a bat... | ['Adenoma', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Child', 'Collagen Type IV', 'Diagnosis, Differential', 'Female', 'Humans', 'Immunohistochemistry', 'Infant', 'Male', 'Middle Aged', 'Pituitary Gland', 'Pituitary Neoplasms', 'Predictive Value of Tests', 'Reticulin'] | 17,550,321 | [['C04.557.470.035'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['M01.060.406'], ['D12.776.860.300.250.400.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.75... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Postoperative D-dimer elevation affects tumor recurrence and the long-term survival in gastric cancer patients who undergo gastrectomy. | INTRODUCTION: We retrospectively evaluated the blood coagulation activity using the D-dimer level in the early period after gastrectomy and investigated whether postoperative hypercoagulation affects tumor recurrence and long-term survival in gastric cancer patients.METHODS: The study involved 650 patients who underwen... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Female', 'Fibrin Fibrinogen Degradation Products', 'Follow-Up Studies', 'Gastrectomy', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Postoperative Period', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk Factors', 'Stomach Neop... | 31,865,480 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['D12.776.124.270.300', 'D12.776.811.300.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Establishment of time-action profiles for regular and NPH insulin using pharmacodynamic modeling. | OBJECTIVE: To provide distinct definitions and quantify the establishment of onset, peak, and duration of action for insulins.RESEARCH DESIGN AND METHODS: We administered single subcutaneous doses of 10 U regular insulin to 10 volunteer subjects and 25 U NPH insulin to 6 healthy male volunteer subjects on separate occa... | ['Adult', 'Blood Glucose', 'Glucose Clamp Technique', 'Humans', 'Injections, Subcutaneous', 'Insulin', 'Insulin, Isophane', 'Male', 'Models, Biological', 'Radioimmunoassay', 'Recombinant Proteins', 'Time Factors'] | 8,112,192 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.620'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D06.472.699.587.200.300.200', 'D12.644.548.586.200.300.200'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Explorative search of distributed bio-data to answer complex biomedical questions. | BACKGROUND: The huge amount of biomedical-molecular data increasingly produced is providing scientists with potentially valuable information. Yet, such data quantity makes difficult to find and extract those data that are most reliable and most related to the biomedical questions to be answered, which are increasingly ... | ['Algorithms', 'Biomedical Technology', 'Computational Biology', 'Genomics', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Sequence Analysis, DNA'] | 24,564,278 | [['G17.035', 'L01.224.050'], ['J01.897.120.050'], ['H01.158.273.180', 'L01.313.124'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.760.700']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Duration of the first agonist EMG burst in ballistic arm movements. | In normal subjects, fast arm movements are accomplished by a diphasic or triphasic EMG activation of the agonist and antagonist muscles. The duration of the first agonist burst (Ag1) has been said to be constant for movements of different size, whilst its amplitude is variable. Previous studies focused on relatively sm... | ['Adult', 'Elbow', 'Electromyography', 'Humans', 'Movement', 'Muscle Contraction', 'Muscles', 'Wrist'] | 6,744,037 | [['M01.060.116'], ['A01.378.800.420'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['G11.427.494'], ['A02.633', 'A10.690'], ['A01.378.800.875']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preoperative imaging in patients undergoing trachelectomy for cervical cancer: validation of a combined T2- and diffusion-weighted endovaginal MRI technique at 3.0 T. | AIM: The aim of this study is to validate high-resolution endovaginal T2- and diffusion-weighted MRI measurements (tumour size, volume and length of uninvolved cervical canal) against histology in patients undergoing trachelectomy.PATIENTS/INTERVENTIONS: 55 consecutive patients 25-44 years with cervical cancer being co... | ['Adult', 'Carcinoma', 'Cervix Uteri', 'Cohort Studies', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Fertility Preservation', 'Humans', 'Hysterectomy', 'Magnetic Resonance Imaging', 'Organ Sparing Treatments', 'Preoperative Care', 'Sensitivity and Specificity', 'Tumor Burden', 'Uterine Cervical Neoplasms'] | 24,582,988 | [['M01.060.116'], ['C04.557.470.200'], ['A05.360.319.679.256'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.825.500.150'], ['E02.875.800.625', 'E04.936.537.562', 'E05.820.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E01.370.350.825.5... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of the universal stress protein F from atypical enteropathogenic Escherichia coli and its prevalence in Enterobacteriaceae. | Atypical enteropathogenic Escherichia coli (aEPEC) are heterogeneous strains in terms of serotypes, adherence patterns and the presence of novel virulence factors. This heterogeneity is intriguing, promoting studies trying to characterize these novel proteins and to better comprehend this pathotype group. In a previous... | ['Citrobacter freundii', 'Enteropathogenic Escherichia coli', 'Escherichia coli Proteins', 'Heat-Shock Proteins', 'Shigella sonnei'] | 27,616,205 | [['B03.440.450.425.200.275', 'B03.660.250.150.100.210'], ['B03.440.450.425.325.300.330', 'B03.660.250.150.180.100.330'], ['D12.776.097.275'], ['D12.776.580.216'], ['B03.440.450.425.850.800', 'B03.660.250.150.730.710']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans. | BACKGROUND: Several observational studies have recently suggested an inverse association of circulating levels of vitamin D with blood pressure. These findings have been based mainly on Caucasian populations; whether this association also exists among Hispanic and African Americans has yet to be definitively determined... | ['Adolescent', 'Adult', 'African Americans', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Atherosclerosis', 'Blood Pressure', 'Body Mass Index', 'Female', 'Hispanic Americans', 'Humans', 'Insulin Resistance', 'Male', 'Middle Aged', 'Motor Activity', 'Phenotype', 'Rural Population', 'Seasons', 'Smoking', 'United States'... | 19,444,222 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126.307'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Practice patterns and family life--a survey of Melbourne medical graduates. | To investigate sex differences in the professional achievements and personal life-styles of graduates, a questionnaire survey was conducted. The sample comprised surviving female medical graduates of the University of Melbourne and an equal number of male medical graduates who were matched by year of graduation. The fi... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Child', 'Child Care', 'Education, Medical, Continuing', 'Employment', 'Family', 'Female', 'Humans', 'Income', 'Life Style', 'Male', 'Middle Aged', 'Personal Satisfaction', 'Physicians, Women', 'Professional Practice', 'Retirement', 'Sampling Studies', 'Sex Factors'... | 2,796,814 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['I01.880.787.293.360', 'N02.421.088'], ['I02.358.212.350', 'I02.358.399.250'], ['N01.824.245'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Heart failure-related hospitalization in the U.S., 1979 to 2004. | OBJECTIVES: The purpose of this study was to determine hospitalizations for heart failure in the U.S. during the past 26 years.BACKGROUND: Heart failure increased in the U.S.; however, little is known about the long-term trends in diseases leading to hospitalizations among patients with heart failure.METHODS: Using Nat... | ['Aged', 'Aged, 80 and over', 'Female', 'Heart Failure', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Patient Discharge', 'Risk Factors', 'Time Factors', 'United States'] | 18,672,162 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.434'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.125', 'N02.421.585.400.610', 'N04.590.233.727.210.125'], ['E05.318.740.600.800.725', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of corticotropin-releasing hormone on ACTH, cortisol and 13, 14-dihydro-15-keto prostaglandin E2 in patients with diabetes insipidus before and after captopril treatment. | A corticotropin-releasing hormone (CRH) test was performed on 7 patients with central diabetes insipidus (DI) and on 7 healthy subjects. The test was repeated on the patients with DI after 3 days of oral treatment with captopril at a dose of 100 mg daily. No significant difference in the responses of plasma ACTH and co... | ['Adrenocorticotropic Hormone', 'Adult', 'Angiotensin-Converting Enzyme Inhibitors', 'Captopril', 'Corticotropin-Releasing Hormone', 'Diabetes Insipidus', 'Dinoprostone', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Vasopressins'] | 8,888,355 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['D27.505.519.389.745.085'], ['D12.125.072.401.623.270'], ['D06.472.699.327.740.140', 'D12.644.400.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Prognosis of functional healing of infantile strabismus]. | One hundred and forth-three patients suffering from infantile strabismus, who had undergone surgery on the horizontal eye muscles between the ages of 0 and 6 years were re-examined with the aim of establishing a correlation between the date of operation and functional healing (binocular single vision in space). In 89 p... | ['Child', 'Child, Preschool', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Prognosis', 'Strabismus'] | 7,347,788 | [['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.789'], ['C10.292.562.887', 'C11.590.810']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer. | TMPRSS2-ERG (T2E) structural rearrangements typify ?50% of prostate tumors and result in overexpression of the ERG transcription factor. Using chromatin, genomic and expression data, we show distinct cis-regulatory landscapes between T2E-positive and non-T2E primary prostate tumors, which include clusters of regulatory... | ['Cell Line, Tumor', 'Cell Movement', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Hepatocyte Nuclear Factor 3-alpha', 'Homeodomain Proteins', 'Humans', 'Male', 'Oncogene Proteins, Fusion', 'Prostatic Neoplasms', 'RNA Interference', 'Receptors, Notch', 'Regulatory Sequences, Nucleic Acid', 'R... | 28,783,165 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['E05.393.332'], ['G05.308.370'], ['D12.776.260.262.750', 'D12.776.260.950.249.500', 'D12.776.660.352.750', 'D12.776.930.318.750', 'D12.776.930.977.249.500'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.602.500.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of steam sterilization of reusable medical devices in primary and secondary care public hospitals in Nepal and factors associated with ineffective sterilization: A nation-wide cross-sectional study. | BACKGROUND: Inadequate sterilization of reusable medical devices can lead to healthcare associated infections (HAIs) through person-to-person or environmental transmission of pathogens. Autoclaving (steam sterilization) is most commonly used for sterilizing medical devices in healthcare facilities. We conducted a natio... | ['Cross-Sectional Studies', 'Equipment Contamination', 'Equipment and Supplies', 'Hospitals, Public', 'Humans', 'Logistic Models', 'Nepal', 'Secondary Care Centers', 'Sterilization'] | 31,751,421 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.540'], ['E07'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability. | Changes in permeability of retinal blood vessels contribute to macular edema and the pathophysiology of numerous ocular diseases, including diabetic retinopathy, retinal vein occlusions, and macular degeneration. Vascular endothelial growth factor (VEGF) induces retinal permeability and macular thickening in these dise... | ['Animals', 'Capillary Permeability', 'Male', 'Mice, Inbred C57BL', 'Papilledema', 'Protein Kinase C', 'Rats, Long-Evans', 'Recombinant Proteins', 'Reperfusion Injury', 'Retinal Vessels', 'Retinitis', 'Tight Junctions', 'Tumor Necrosis Factor-alpha', 'Vascular Endothelial Growth Factor A'] | 30,220,554 | [['B01.050'], ['G03.143.330', 'G09.330.165'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['C10.292.700.900', 'C11.640.710'], ['D08.811.913.696.620.682.700.725'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['D12.776.828'], ['C14.907.725', 'C23.550.767.877'], ['A07.015.611']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of cellular components in granulomatous inflammatory response in Piaractus mesopotamicus model. | The present study aimed to describe and characterize the cellular components during the evolution of chronic granulomatous inflammation in the teleost fish pacus (P. mesopotamicus) induced by Bacillus Calmette-Guerin (BCG), using S-100, iNOS and cytokeratin antibodies. 50 fish (120±5.0 g) were anesthetized and 45 inocu... | ['Animals', 'Disease Models, Animal', 'Fishes', 'Granuloma', 'Keratins', 'Muscles', 'Mycobacterium bovis', 'Nitric Oxide Synthase Type II', 'S100 Proteins'] | 25,811,875 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.493'], ['C15.604.515.292', 'C23.550.382'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['A02.633', 'A10.690'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['D08.811.682.664.500.772.500', 'D12.776.15... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The interface of mental health and human rights in Indigenous peoples: triple jeopardy and triple opportunity. | OBJECTIVE: Insufficient understanding of the reciprocal interactions between health and human rights, mental health and human rights and the realization of all human rights by Indigenous peoples constitute a triple jeopardy in how these topics are currently being addressed and/or openly antagonized. This paper will att... | ['Decision Making', 'Health Policy', 'Human Rights', 'Humans', 'Mental Health', 'Policy Making', 'Population Groups'] | 18,027,129 | [['F02.463.785.373'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['N03.706.742'], ['M01.686', 'N01.224.708']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Selective cytokine production by epithelial cells following exposure to Escherichia coli. | This study compared the repertoire of cytokines produced by epithelial cell lines and human peripheral blood monocytes in response to Escherichia coli. The A-498 and J82 urinary tract epithelial cell lines and human peripheral blood monocytes were exposed to E. coli Hu734. The cytokine content of single cells was detec... | ['Adult', 'Cell Line', 'Cytokines', 'Epithelial Cells', 'Epithelium', 'Escherichia coli', 'Fluorescent Antibody Technique', 'Humans', 'Kidney', 'Monocytes', 'Neutrophils', 'Urinary Bladder'] | 8,423,089 | [['M01.060.116'], ['A11.251.210'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.436'], ['A10.272'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.1... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
TTF1-positive Papillary Epithelial Tumor of Pituitary: An Epithelial Variant of Pituicytoma? | Low-grade epithelial tumor of pituitary region with dominant papillary architecture is extremely rare. We describe a case of 20-year female who had a recurrent nonfunctioning pituitary tumor. Histologic examination revealed a low-grade epithelial tumor with predominant papillary architecture, lined by cuboidal to colum... | ['Adult', 'Biomarkers, Tumor', 'DNA-Binding Proteins', 'Female', 'Humans', 'Neoplasm Proteins', 'Pituitary Hormones', 'Pituitary Neoplasms', 'Transcription Factors'] | 31,809,313 | [['M01.060.116'], ['D23.101.140'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.624'], ['D06.472.699.631', 'D12.644.548.691'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.477.600', 'C10.228.140.617.738.675', 'C10.551.240.250.700.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of geniculocortical projections to visual cortex in rat: evidence early ingrowth and synaptogenesis. | Anterograde movement of DiI and transneuronal transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) were used to study the temporal and laminar patterns of ingrowth of the geniculocortical projection to visual cortex in fetal and postnatal rats. The development of this projection was compared to patterns ... | ['Afferent Pathways', 'Animals', 'Animals, Newborn', 'Axons', 'Carbocyanines', 'Fluorescent Dyes', 'Geniculate Bodies', 'Horseradish Peroxidase', 'Neural Pathways', 'Rats', 'Rats, Sprague-Dawley', 'Synapses', 'Visual Cortex', 'Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate', 'Wheat Germ Agglutinins'] | 7,691,903 | [['A08.612.220'], ['B01.050'], ['B01.050.050.282'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D02.455.326.397.300'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A08.186.211.200.317.826.701.444'], ['D08.811.682.732.512'], ['A08.612'], ['B01.050.150.900.649.313.992.635.505.700'], [... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Understanding the binding mode and function of BMS-488043 against HIV-1 viral entry. | A recently discovered small-molecule inhibitor, BMS-488043 (BMS-488), for the invasion of Human immunodeficiency virus Type 1 (HIV-1), shows a high activity against the entry of diversified HIV-1. Docking and molecular dynamic studies have been carried out to understand the binding mode of BMS-488 to gp120 as well as t... | ['CD4 Antigens', 'HIV Envelope Protein gp120', 'HIV Fusion Inhibitors', 'HIV Infections', 'HIV-1', 'Humans', 'Indoles', 'Molecular Dynamics Simulation', 'Piperazines', 'Protein Binding', 'Protein Conformation', 'Pyruvic Acid', 'Virus Internalization'] | 21,465,559 | [['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.970.880.325.164.249', 'D23.050.327.520.350'], ['D27.505.519.957.500', 'D27.505.954.122.388.077.088.209', 'D27.505.954.122... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The most common chromosome aberration detected by high-resolution comparative genomic hybridization in vulvar intraepithelial neoplasia is not seen in vulvar squamous cell carcinoma. | We analyzed genetic changes in condylomas (four cases), vulvar intraepithelial neoplasia I-III (VIN I-III, eleven cases), and primary vulvar squamous cell carcinomas (VSCC, ten cases) by high-resolution comparative genomic hybridization (HR-CGH) and flowcytometry. All samples were also human papilloma virus (HPV)-genot... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aneuploidy', 'Carcinoma in Situ', 'Carcinoma, Squamous Cell', 'Chromosome Aberrations', 'Chromosomes, Human, Pair 1', 'Condylomata Acuminata', 'Female', 'Flow Cytometry', 'Genotype', 'Humans', 'Image Processing, Computer-Assisted', 'Middle Aged', 'Nucleic Acid Hybridization', 'Pa... | 15,218,240 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C04.557.470.200.240'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['C01.221.812.640.220', ... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Isobavachalcone and bavachinin from Psoraleae Fructus modulate Aâ42 aggregation process through different mechanisms in vitro. | Spontaneous aggregation of Aâ is a key factor in the development of Alzheimer's disease. In searching for Aâ aggregation inhibitors from traditional Chinese herbal medicines, we identified two active compounds from Psoraleae Fructus, namely isobavachalcone and bavachinin. We further demonstrated that the two compounds ... | ['Amyloid beta-Peptides', 'Cell Line', 'Cell Survival', 'Chalcones', 'Drugs, Chinese Herbal', 'Flavonoids', 'Fruit', 'Humans', 'Peptide Fragments', 'Protein Multimerization', 'Psoralea'] | 23,907,009 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['A11.251.210'], ['G04.346'], ['D02.522.818.222', 'D03.383.663.283.266.450.221', 'D03.633.100.150.266.450.221'], ['D20.215.784.500.350', 'D26.335'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Two linear rules relate the latencies of visual responses to their critical durations. | The latency of a neural response sets a limit on its critical duration since stimulation delivered after a response has already occurred can no longer affect that response. However, this tautologic upper limit does not uniquely define the critical duration. Intracellular recordings from the lateral eye of Limulus yield... | ['Animals', 'Horseshoe Crabs', 'Membrane Potentials', 'Optic Nerve', 'Photic Stimulation', 'Photoreceptor Cells', 'Reaction Time', 'Recruitment, Neurophysiological', 'Retina', 'Visual Perception'] | 705,352 | [['B01.050'], ['B01.050.500.131.450'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.800.800.120.680'], ['E05.723.729'], ['A08.675.650.850.625', 'A08.675.650.915.937', 'A08.800.950.937', 'A09.371.729.831.625', 'A11.671.650.850.625', 'A11.671.650.915.937'], ['E05.796.817', 'F02.830.650', 'F04.669.817',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Calcium, phosphorus, and magnesium contents of human milk during early lactation. | Early milk samples from 102 American mothers were examined for Ca, P, and Mg contents in relation to stage of lactation, intake of prenatal mineral supplements, maternal age, parity, and previous history of lactation. A total of 415 samples were collected at three stages of lactation: early transitional (4-7 days postp... | ['Calcium', 'Circadian Rhythm', 'Female', 'Food, Fortified', 'Humans', 'Lactation', 'Magnesium', 'Maternal Age', 'Milk, Human', 'Parity', 'Phosphorus', 'Pregnancy', 'Time Factors'] | 6,683,754 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.180.562.190'], ['G07.203.300.515', 'J02.500.515'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.523', 'G08.686.702.500'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Biological regeneration of manganese (IV) and iron (III) for anaerobic metal oxide-mediated removal of pharmaceuticals from water. | Applying manganese(IV)- or iron(III)-(hydr)oxides to remove pharmaceuticals from water could be attractive, due to the capacity of these metal oxides to remove pharmaceuticals and be regenerated. As pharmaceutical removal under anaerobic conditions is foreseen, Mn(IV) or Fe(III) regeneration under anaerobic conditions,... | ['Anaerobiosis', 'Ferric Compounds', 'Manganese Compounds', 'Oxidation-Reduction', 'Oxides', 'Pharmaceutical Preparations', 'Water Pollutants, Chemical', 'Water Purification'] | 29,864,703 | [['G02.111.062', 'G03.078'], ['D01.490.100'], ['D01.530'], ['G02.700', 'G03.295.531'], ['D01.248.497.158.685', 'D01.650.550'], ['D26'], ['D27.888.284.903.655'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Distribution of RNA editing sites in Oenothera mitochondrial mRNAs and rRNAs. | To investigate whether RNA editing in plant mitochondria modifies structural RNAs as well as protein-coding RNAs we compared the genomic-encoded information with the respective transcripts of several genes in Oenothera. The genes analysed are the 5S, 18S and 26 S rRNAs, the alpha-subunit of ATPase (atpA), cytochrome b ... | ['Adenosine Triphosphatases', 'Amino Acid Sequence', 'Base Sequence', 'Cytochrome b Group', 'DNA', 'Electron Transport Complex IV', 'Mitochondria', 'Molecular Sequence Data', 'Open Reading Frames', 'Plants', 'RNA', 'RNA Processing, Post-Transcriptional', 'RNA, Mitochondrial', 'RNA, Ribosomal', 'RNA, Ribosomal, 18S', 'R... | 1,725,505 | [['D08.811.277.040.025'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.244.187', 'D12.776.422.220.187'], ['D13.444.308'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Variable threshold as a model for selective attention, (de)sensitization, and anesthesia in associative neural networks. | We study the influence of a variable neuronal threshold on fixed points and convergence rates of an associative neural network in the presence of noise. We allow a random distribution in the activity levels of the patterns stored, and a modification to the standard Hebbian learning rule is proposed for this purpose. Th... | ['Anesthesia', 'Animals', 'Attention', 'Humans', 'Learning', 'Mathematics', 'Models, Neurological', 'Neurons', 'Probability', 'Synapses'] | 2,004,134 | [['E03.155'], ['B01.050'], ['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['H01.548'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['A08.850', 'A11.284.149.165.420.780']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Application of vasopressin radioimmunoassay to clinical study: role of vasopressin in hypo- and hypernatremia and some other disorders of water metabolism. | Plasma and urinary arginine vasopressin (AVP) in normal subjects and in patients with various water metabolism disorders was measured using a sensitive, specific radioimmunoassay. The AVP plasma levels in normal subjects were 3.1 +/- 1.2 pg/ml. The parallel changes in plasma osmolality, plasma AVP concentration, and ur... | ['Adrenal Insufficiency', 'Adult', 'Animals', 'Arginine Vasopressin', 'Ascites', 'Diabetes Insipidus', 'Dogs', 'Edema', 'Humans', 'Hypernatremia', 'Hyponatremia', 'Hypotension, Orthostatic', 'Infant', 'Neoplasms', 'Osmolar Concentration', 'Radioimmunoassay', 'Vasopressins', 'Water'] | 668,388 | [['C19.053.500'], ['M01.060.116'], ['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['C23.550.081'], ['C12.777.419.135', 'C13.351.968.419.135', 'C19.700.159'], ['B01.050.150.900.649.313.750.250.216.200'], ['C23.888.277'... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ian4 is required for mitochondrial integrity and T cell survival. | Apoptosis is a regulated cell death program controlled by extrinsic and intrinsic signaling pathways. The intrinsic pathway involves stress signals that activate pro-apoptotic members of the Bcl-2 family, inducing permeabilization of mitochondria and release of apoptogenic factors. These proteins localize to the outer ... | ['Animals', 'Apoptosis', 'Caspases', 'Cell Survival', 'DNA Fragmentation', 'Female', 'GTP-Binding Proteins', 'Male', 'Membrane Potentials', 'Membrane Proteins', 'Mitochondria', 'Mitochondrial Proteins', 'RNA, Small Interfering', 'Rats', 'Rats, Inbred WF', 'T-Lymphocytes'] | 12,930,893 | [['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.346'], ['G05.200.230'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['D12.776.543'], ['A11.284.430.214.190.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychological issues in geriatric oncology. | Optimism about improved survival from cancer has increased. However, even with tremendous improvements in screening techniques and treatment, a cancer diagnosis may shatter the dream of a dignified old age for elderly patients. Cancer diagnosis and treatment often produce psychological stresses resulting from the actua... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Anxiety', 'Delirium', 'Dementia', 'Depression', 'Female', 'Geriatric Psychiatry', 'Health Services for the Aged', 'Humans', 'Male', 'Mental Health Services', 'Neoplasms'] | 19,761,071 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F01.470.132'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['C10.228.140.380', 'F03.615.400'], ['F01.145.126.350'], ['F04.096.544.380', 'H02.403.690.260'], ['N02.421.320'],... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A new, automated and accurate in vitro method to quantify endothelial cells attached to vascular prostheses. | Over a decade ago the idea of endothelial cell seeding was introduced in an attempt to improve the function of small caliber vascular prostheses. Although endothelial cell seeding is currently being applied clinically, several questions regarding the functional properties of the seeded endothelial cells remain. Evaluat... | ['Automation', 'Blood Vessel Prosthesis', 'Cell Count', 'Cells, Cultured', 'Endothelium, Vascular', 'Fluoresceins', 'Humans', 'Reproducibility of Results'] | 7,974,363 | [['J01.897.104'], ['E07.695.110'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.32... | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Naltrexone in the short-term decreases antiparkinsonian response to l-Dopa and in the long-term increases dyskinesias in drug-na?ve parkinsonian monkeys. | Nigrostriatal dopaminergic denervation and levodopa therapy in animal models and in parkinsonian patients are associated with an enhanced opioid transmission in the striatum. The functional role of this increase has always been a subject of debate. In this study two groups of drug-na?ve macaque monkeys with MPTP-induce... | ['1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine', 'Analysis of Variance', 'Animals', 'Antiparkinson Agents', 'Behavior, Animal', 'Disease Models, Animal', 'Dyskinesias', 'Female', 'Levodopa', 'Macaca fascicularis', 'Motor Activity', 'Naltrexone', 'Narcotic Antagonists', 'Ovariectomy', 'Parkinsonian Disorders', 'Statisti... | 15,996,565 | [['D03.383.725.450'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.954.427.090.050'], ['F01.145.113'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.662.262', 'C10.597.350', 'C23.888.592.350'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Calcium antagonistic properties of the sesquiterpene T-cadinol: a comparison with nimodipine in the isolated rat aorta. | (+)-T-Cadinol is a sesquiterpene with smooth muscle relaxing properties. In the isolated rat aorta, T-cadinol relaxed contractions induced by 60 mM K+ in a concentration-dependent fashion. The dihydropyridine calcium antagonist nimodipine was approximately 4,000 times more potent than T-cadinol. While both drugs nearly... | ['3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester', 'Animals', 'Aorta', 'Calcium Channel Blockers', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Nimodipine', 'Rats', 'Rats, Inbred Strains', 'Sesquiterpenes'] | 1,724,563 | [['D03.383.725.203.600', 'D03.383.725.547.900'], ['B01.050'], ['A07.015.114.056'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['G11.427.494'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D03.383.725.203.570', 'D03.383.725.547.570'], ['B01.050.150.900.649.313.992.635.505.700'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wound repair and proliferation of bronchial epithelial cells regulated by CTNNAL1. | Adhesion molecules play vital roles in airway hyperresponsiveness (AHR) or airway inflammation. Our previous study indicated that adhesion molecule catenin alpha-like 1 (CTNNAL1) is relevant closely to asthma susceptibility, but its biological function or significance is still unclear. In the present study, we observed... | ['Airway Resistance', 'Animals', 'Asthma', 'Bronchi', 'Cell Adhesion', 'Cell Movement', 'Cell Proliferation', 'Cells, Cultured', 'Cytoskeletal Proteins', 'Disease Models, Animal', 'Epithelial Cells', 'Fibronectins', 'Focal Adhesion Kinase 1', 'Gene Expression', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Oligodeoxyribonu... | 17,647,259 | [['E01.370.386.700.050', 'G09.772.060'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A04.411.125'], ['G04.022'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D12.776.220'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.436'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinically determined type of 18F-fluoro-2-deoxyglucose uptake as an alternative prognostic marker in resectable pancreatic cancer. | PURPOSE: To investigate the association between clinical PET (positron emission tomography) type and oncologic outcome in resectable pancreatic cancer.METHODS: Between January 2008 and October 2012, patients who underwent potentially curative resection for resectable pancreatic ductal adenocarcinoma without neoadjuvant... | ['Aged', 'Carcinoma, Pancreatic Ductal', 'Disease-Free Survival', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Male', 'Middle Aged', 'Pancreatectomy', 'Pancreatic Neoplasms', 'Positron-Emission Tomography', 'Prognosis', 'Radiopharmaceuticals', 'Retrospective Studies', 'Tumor Burden'] | 28,235,029 | [['M01.060.116.100'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.85... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
3,3'-bimorpholine derivatives as a new class of organocatalysts for asymmetric Michael addition. | New N-alkyl-3,3'-bimorpholine derivatives (iPBM) were revealed to be efficient organocatalysts for the asymmetric direct Michael addition of aldehydes to nitroolefins and a vinyl sulfone. In these transformations using iPBM, 1,4-adducts were afforded in high yields, with good to high levels of diastereo- and enantiosel... | ['Aldehydes', 'Alkenes', 'Catalysis', 'Models, Molecular', 'Molecular Structure', 'Morpholines', 'Nitro Compounds', 'Stereoisomerism', 'Vinyl Compounds'] | 16,737,313 | [['D02.047'], ['D02.455.326.271'], ['G02.130'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D03.383.533.640'], ['D02.640'], ['G02.607.445.682'], ['D02.455.326.271.884']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors Interfering with Delineation on MRCP of Pancreaticobiliary Maljunction in Paediatric Patients. | BACKGROUND: The aim of this study was to assess factors for delineating the pancreaticobiliary junction in the presence of pediatric congenital choledochal cysts (CCC) using Magnetic resonance cholangiopancreatography (MRCP).METHODS: Retrospective review of medical records for 48 patients with CCC was conducted, includ... | ['Adolescent', 'Age Factors', 'Bile Ducts', 'Child', 'Child, Preschool', 'Cholangiopancreatography, Endoscopic Retrograde', 'Cholangiopancreatography, Magnetic Resonance', 'Choledochal Cyst', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Logistic Models', 'Male', 'Multivariate Analysis', 'Pancreatic Ducts', 'Retros... | 27,104,956 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['A03.159.183'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['E01.370.350.825.500.100', 'E01.370.372.207'], ['C04.182.1... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Novel approach for overcoming the stability challenges of lipid-based excipients. Part 2: Application of polyglycerol esters of fatty acids as hot melt coating excipients. | The application of hot melt coating (HMC) as an economic and solvent-free technology is restricted in pharmaceutical development, due to the instable solid-state of HMC excipients resulting in drug release instability. We have previously introduced polyglycerol esters of fatty acids (PGFAs) with stable solid-state (Par... | ['Calorimetry, Differential Scanning', 'Chemistry, Pharmaceutical', 'Crystallization', 'Drug Stability', 'Drug Storage', 'Esters', 'Excipients', 'Fatty Acids', 'Glycerol', 'Hot Temperature', 'Lipids', 'Polymers', 'Technology, Pharmaceutical', 'X-Ray Diffraction'] | 31,982,575 | [['E05.196.131.310', 'E05.196.370.310'], ['H01.158.703.007', 'H01.181.466'], ['E05.196.300', 'G02.171'], ['E05.916.330'], ['E05.916.350'], ['D02.241.400'], ['D26.650.700.419', 'D27.720.744.770.419'], ['D10.251'], ['D02.033.800.875.500', 'D09.853.875.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
A study of patient acceptance of double-contrast barium enema and colonoscopy. Which procedure is preferred by patients? | To our knowledge, no previous study has addressed the question of which method of evaluation of the lower gastrointestinal tract is preferred by patients, air-contrast barium enema or colonoscopy. Over a four-month period, we asked 189 consecutive patients who had undergone colonoscopy to express their preference for e... | ['Adult', 'Aged', 'Aged, 80 and over', 'Barium', 'Colonoscopy', 'Enema', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Acceptance of Health Care'] | 3,689,069 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['E02.319.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differential relationships between sub-traits of BIS-11 impulsivity and executive processes: an ERP study. | There is mixed evidence for a relationship between impulsivity and executive functions. Although impulsivity is heterogeneous, previous research did not examine partial relationships controlling for shared variance across sub-traits to evaluate the specificity of these associations. Eighty-five undergraduates completed... | ['Adolescent', 'Attention', 'Cognition Disorders', 'Conflict, Psychological', 'Electroencephalography', 'Evoked Potentials', 'Executive Function', 'Female', 'Humans', 'Impulsive Behavior', 'Inhibition, Psychological', 'Male', 'Neuropsychological Tests', 'Photic Stimulation', 'Principal Component Analysis', 'Psychomotor... | 22,659,220 | [['M01.060.057'], ['F02.830.104.214'], ['F03.615.250'], ['F01.658.209'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F04.711.513'], ['E05.723.72... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Biomass flow and structure of a tropical upwelling ecosystem in La Guajira, Colombian Caribbean]. | La Guajira is an exploited tropical upwelling ecosystem in the Colombian Caribbean coast. A trophic model of 27 functional groups was constructed using the ECOPATH 5.0 Beta software to integrate the available information on the ecosystem. The model allowed a comparison with other trophic flow models of upwelling ecosys... | ['Animals', 'Biomass', 'Caribbean Region', 'Colombia', 'Ecosystem', 'Fishes', 'Invertebrates', 'Marine Biology', 'Models, Biological', 'Phytoplankton'] | 18,457,163 | [['B01.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.107.084'], ['Z01.107.757.284'], ['G16.500.275.157', 'N06.230.124'], ['B01.050.150.900.493'], ['B01.050.500'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500'], ['E05.599.395'], ['B05.080.500.600']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Conditional inhibition of autophagy genes in adult Drosophila impairs immunity without compromising longevity. | Immune function declines with age in Drosophila and humans, and autophagy is implicated in immune function. In addition, autophagy genes are required for life span extension caused by reduced insulin/IGF1-like signaling and dietary restriction in Caenorhabditiselegans. To test if the autophagy pathway might be limiting... | ['Aging', 'Animals', 'Animals, Genetically Modified', 'Autophagy', 'Drosophila', 'Drosophila Proteins', 'Escherichia coli', 'Escherichia coli Infections', 'Fasting', 'Gene Expression Regulation', 'Immunity', 'Longevity', 'Male', 'Staining and Labeling'] | 18,955,126 | [['G07.345.124'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G04.011'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G05.308'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electron-transport components of the 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine delta 12-desaturase (delta 12-desaturase) in microsomal preparations from developing safflower (Carthamus tinctorius L.) cotyledons. | The major cytochrome in microsomal membrane preparations from developing seeds of safflower (Carthamus tinctorius, var High Linoleate), has a reduced-minus-oxidized difference spectrum characteristic of a b-type cytochrome, and was identified from its midpoint-potential (E'7.2) value as cytochrome b5. Cytochromes P-450... | ['Cytochromes b5', 'Electron Transport', 'Fatty Acid Desaturases', 'Kinetics', 'Microsomes', 'Oxidation-Reduction', 'Plants', 'Spectrophotometry'] | 2,264,826 | [['D08.244.187.500', 'D12.776.422.220.187.500'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D08.811.682.690.708.392'], ['G01.374.661', 'G02.111.490'], ['A11.284.835.540'], ['G02.700', 'G03.295.531'], ['B01.650'], ['E05.196.712.726', 'E05.196.867.826']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patterns of gastro-intestinal parasites and commensals as an index of population and ecosystem health: the case of sympatric western chimpanzees (Pan troglodytes verus) and guinea baboons (Papio hamadryas papio) at Fongoli, Senegal. | The exponential decline of great apes over the past 50 years has resulted in an urgent need for data to inform population viability assessment and conservation strategies. Health monitoring of remaining ape populations is an important component of this process. In support of this effort, we examined endoparasitic and c... | ['Animals', 'Ciliophora', 'Ecosystem', 'Entamoeba', 'Feces', 'Helminthiasis, Animal', 'Helminths', 'Host-Parasite Interactions', 'Pan troglodytes', 'Papio papio', 'Prevalence', 'Protozoan Infections, Animal', 'Senegal', 'Symbiosis'] | 20,853,397 | [['B01.050'], ['B01.043.185'], ['G16.500.275.157', 'N06.230.124'], ['B01.046.500.100.700.335'], ['A12.459'], ['C01.610.335.349', 'C01.610.701.377', 'C22.674.377'], ['B01.050.500.500'], ['G16.527.200.400'], ['B01.050.150.900.649.313.988.400.112.400.620'], ['B01.050.150.900.649.313.988.400.112.199.120.610.600'], ['E05.31... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Teratogenic effects of endotoxin on the golden hamster. | Gram-negative urinary tract infections in pregnant women have been implicated as causes of maternal endotoxemia and a subsequent higher incidence of malformations in their offspring. A study was performed to evaluate the effects of endotoxin on the development of the golden hamster. Endotoxin was shown to be extremely ... | ['Animals', 'Cricetinae', 'Endotoxins', 'Escherichia coli', 'Female', 'Fetal Resorption', 'Mesocricetus', 'Pregnancy', 'Teratogens'] | 6,133,368 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['D23.946.123.329'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C13.703.223.300', 'C23.550.260.585.260'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['G08.686.784.769'], ['D27.888.569.864']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interest and participation in a college student alcohol intervention study as a function of typical drinking. | OBJECTIVE: This research explored the relationship between typical alcohol consumption and interest in participating in a brief alcohol intervention study and between typical consumption and actual participation in the study among students recruited to participate in an intervention study. We predicted a curvilinear re... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Chi-Square Distribution', 'Confidence Intervals', 'Female', 'Humans', 'Male', 'Motivation', 'Students', 'Universities'] | 15,700,511 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['M01.848'], ['I02... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Cauliflower growths in trophic ulcers of leprosy--a 10 year study. | A 10 year study of cauliflower growths in trophic ulcers of leprosy patients was done. Seventy five cases were seen, out of which seventy two were in foot and three in hand. Eventhough appearance was like that of malignancy, malignant change was seen only in four cases and in other seventy one cases it was pseudoepithe... | ['Adult', 'Aged', 'Biopsy', 'Female', 'Foot Diseases', 'Hand', 'Humans', 'Hyperplasia', 'Leprosy', 'Male', 'Middle Aged', 'Skin Ulcer'] | 3,745,997 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C05.360', 'C17.800.321'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['C01.150.252.410.040.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gender Disparities in Patients With Alcoholic Liver Disease Evaluated for Liver Transplantation. | BACKGROUND: The morbidity and mortality from alcohol-related liver disease (ALD) is increasing in the United States. However, little is known about gender differences in evaluation and listing for liver transplantation (LT) in patients with ALD.METHODS: This is a retrospective review of adult patients with ALD evaluate... | ['Female', 'Follow-Up Studies', 'Humans', 'Liver Diseases, Alcoholic', 'Liver Transplantation', 'Male', 'Middle Aged', 'Morbidity', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Sex Distribution', 'Sex Factors', 'Survival Rate', 'Transplant Recipients', 'United States'] | 31,283,683 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.645', 'C25.775.100.087.645'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['E05.318.308.985.525', 'N01.224.935.597... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Relationships Among Obesity, Type 2 Diabetes, and Plasma Cytokines in African American Women. | OBJECTIVE: The principal objective of this investigation was to identify novel cytokine associations with BMI and type 2 diabetes (T2D).METHODS: Cytokines were profiled from African American women with obesity who donated plasma to the Komen Tissue Bank. Multiplex bead arrays of analytes were used to quantify 88 cytoki... | ['African Americans', 'Chemokines', 'Cytokines', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Middle Aged', 'Obesity', 'United States'] | 28,840,653 | [['M01.686.508.100.100', 'M01.686.754.100'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Hand arterial blood flow responses to local venous congestion. | Hand and forearm blood flows were measured in 12 subjects by means of a range-gated D?ppler velocimeter, in basal conditions and after inflation (30, 50, 60, 70, and 90 mmHg) of a venous occlusion cuff on the middle part of the forearm. In basal conditions, there were significant decreases in radial, ulnar, and brachia... | ['Adult', 'Arteries', 'Blood Pressure', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Regional Blood Flow', 'Veins'] | 7,246,758 | [['M01.060.116'], ['A07.015.114'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.330.100.780'], ['A07.015.908']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Demonstration by a novel genetic technique that leader peptidase is an essential enzyme of Escherichia coli. | It was previously shown that two separate regions of DNA are required for expression of the cloned leader peptidase gene on plasmid pTD101 (T. Date and W. Wickner, Proc. Natl. Acad. Sci. U.S.A. 78:6106-6110, 1981). Both loci have been mapped in detail, and their roles have been established. A 1.3-kilobase region, terme... | ['Chromosome Mapping', 'Chromosomes, Bacterial', 'DNA, Bacterial', 'Endopeptidases', 'Escherichia coli', 'Gene Expression Regulation', 'Genes, Bacterial', 'Membrane Proteins', 'Nucleic Acid Hybridization', 'Plasmids', 'Serine Endopeptidases', 'Transformation, Bacterial'] | 6,339,483 | [['E05.393.183'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['D13.444.308.212'], ['D08.811.277.656.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D12.776.543'], ['E05.393.661', 'G02.111.611'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tetrazolium agar overlay in test for Mycoplasma pneumoniae. | In this rapid presumptive test for Mycoplasma pneumoniae, subculture is not required, and tetrazolium reduction is evident in 1 hr or less. | ['Aerobiosis', 'Agar', 'Bacteriological Techniques', 'Cell Count', 'Chlorides', 'Mycoplasma', 'Tetrazolium Salts', 'Time Factors'] | 4,560,467 | [['G02.111.017', 'G03.049'], ['D09.698.360.041'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D01.210.450.150', 'D01.248.497.158.215'], ['B03.440.860.580.553.553'], ['D03.383.129.617.700'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The 'extremely ancient' chromosome that isn't: a forensic bioinformatic investigation of Albert Perry's X-degenerate portion of the Y chromosome. | Mendez and colleagues reported the identification of a Y chromosome haplotype (the A00 lineage) that lies at the basal position of the Y chromosome phylogenetic tree. Incorporating this haplotype, the authors estimated the time to the most recent common ancestor (TMRCA) for the Y tree to be 338,000 years ago (95% CI=23... | ['Chromosomes, Human, X', 'Chromosomes, Human, Y', 'Evolution, Molecular', 'Fossils', 'Haplotypes', 'Humans', 'Mutation', 'Polymorphism, Genetic'] | 24,448,544 | [['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['G05.045.250', 'G16.075.250'], ['I01.076.368.584.311'], ['G05.380.360'], ['B01.050... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma. | BACKGROUND: Increased preoperative serum squamous cell carcinoma antigen (SCC-Ag) concentrations have been found to be associated with advanced stage and poor prognosis in lung and cervical cancers. Because little was known about the significance of SCC-Ag concentration in patients with esophageal cancer, the aim of th... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antigens, Neoplasm', 'Carcinoembryonic Antigen', 'Carcinoma, Squamous Cell', 'Disease Progression', 'Esophageal Neoplasms', 'Esophagectomy', 'Female', 'Humans', 'Lymph Node Excision', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Osmolar Concentration', 'Postoperative Period', 'Pro... | 12,773,976 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.285'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C23.550.291.656'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of vitamin D3 in regulation of interleukin-6 and osteopontin expression in liver of diabetic mice. | OBJECTIVE: To study the link between hepatic interleukin-6 (IL-6) and osteopontin (OPN) gene expression and vitamin D3 status associated with type 1 diabetes in mice; and to evaluate the effects of vitamin D3 treatment (800 IU/kg of body weight for 6 weeks) on diabetes-induced impairments.MATERIALS AND METHODS: mRNA le... | ['Animals', 'Cholecalciferol', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 1', 'Gene Expression Regulation', 'Interleukin-6', 'Liver', 'Mice', 'Osteopontin'] | 27,424,994 | [['B01.050'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G05.308'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Updating reactivated memories in infancy: I. Passive- and active-exposure effects. | This study examined the vulnerability of infants' reactivated memories to modification. In three experiments, one hundred eight 3-month-olds learned to move a distinctive mobile by kicking. After the operant task was forgotten, its memory was recovered by a reactivation treatment. Immediately afterward, attempts were m... | ['Analysis of Variance', 'Conditioning, Psychological', 'Cues', 'Discrimination Learning', 'Female', 'Habituation, Psychophysiologic', 'Humans', 'Infant', 'Inhibition, Psychological', 'Male', 'Memory, Short-Term', 'Mental Recall', 'Psychomotor Performance', 'Recognition, Psychology', 'Retention, Psychology', 'Task Perf... | 15,959,898 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.463.425.179'], ['F02.463.425.234'], ['F02.463.425.280'], ['F02.463.425.393', 'F02.830.422', 'G11.561.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F02.463.425.540... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The stay-green phenotype of TaNAM-RNAi wheat plants is associated with maintenance of chloroplast structure and high enzymatic antioxidant activity. | TaNAM transcription factors play an important role in controlling senescence, which in turn, influences the delivery of nitrogen, iron and other elements to the grain of wheat (Triticum aestivum) plants, thus contributing to grain nutritional value. While lack or diminished expression of TaNAMs determines a stay-green ... | ['Antioxidants', 'Carbohydrates', 'Chlorophyll', 'Chloroplasts', 'Electrophoresis, Polyacrylamide Gel', 'Iron', 'Oxidative Stress', 'Phenotype', 'Photosystem II Protein Complex', 'Plant Leaves', 'Plant Proteins', 'RNA Interference', 'Solubility', 'Sulfhydryl Compounds', 'Transcription Factors', 'Triticum'] | 27,061,370 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D09'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['A11.284.430.214.190.875.700.140'], ['E05.196.401.402', 'E05.301.300.319'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G03.673', 'G07.775.750'], ['G05.695'],... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lymphatic clearance of the human skin in patients with acute deep vein thrombosis using a novel fluorescent technique. | The purpose of this study was to investigate lymphatic clearance of the human skin in patients with acute deep thrombosis of the femoral vein. In 13 patients with deep vein thrombosis and no other cause for swelling of the limbs, lymphatic clearance of the skin at the foot was measured. Ten microliters of fluorescein i... | ['Adult', 'Aged', 'Dextrans', 'Female', 'Fluorescein-5-isothiocyanate', 'Fluorescence', 'Fluorescent Dyes', 'Humans', 'Injections, Intradermal', 'Lymph', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Plasma Substitutes', 'Skin', 'Venous Thrombosis'] | 17,036,633 | [['M01.060.116'], ['M01.060.116.100'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.400', 'D04.711.347.400'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Generic data modelling and use of XML standard for home telemonitoring of chronically ill patients. | In recent years, internet-based home telemonitoring systems that allow transmission of patient data to a central database and offer immediate access to the data by the care providers have become available. The adoption of Extensible Mark-up Language (XML) as a W3C standard has generated a lot of interest in the potenti... | ['Chronic Disease', 'Humans', 'Internet', 'Italy', 'Monitoring, Physiologic', 'Programming Languages'] | 15,460,681 | [['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['Z01.542.489'], ['E01.370.520'], ['L01.224.900.780']] | ['Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
An extracorporeal shunt for the measurement of coronary flow in the closed-chest dog. | An extracorporeal shunt circuit interposed between the left carotid artery and the left coronary ostium employs an electromagnetic flowmeter to measure coronary blood flow in the closed-chest anesthetized dog. Flow may be measured with the animal's arterial pressure as the driving force; introduction of a roller pump, ... | ['Animals', 'Assisted Circulation', 'Blood Pressure', 'Coronary Circulation', 'Dogs', 'Methods', 'Rheology'] | 141,892 | [['B01.050'], ['E04.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.581'], ['E05.830', 'H01.671.808']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The association of DNA methylation and brain volume in healthy individuals and schizophrenia patients. | Both methylation and brain volume patterns hold important biological information for the development and prognosis of schizophrenia (SZ). A combined study to probe the association between them provides a new perspective to understanding SZ. Genomic methylation of peripheral blood and regional brain volumes derived from... | ['Adult', 'Brain', 'Cerebellum', 'CpG Islands', 'DNA Methylation', 'Female', 'Genetic Association Studies', 'Genome, Human', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Schizophrenia', 'Young Adult'] | 26,381,449 | [['M01.060.116'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['E05.393.385'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
"Giant" senile sebaceous hyperplasia. | Although the usual size of senile sebaceous hyperplasia is 2 to 3 mm in diameter, we report one "giant" nodular case on the face. The patient is a 75-year-old Japanese man with a dome-shaped, skin-colored nodule on his right cheek. The lesion was 10 mm in diameter and had multiple small umbilications on its surface. He... | ['Age Factors', 'Aged', 'Diagnosis, Differential', 'Facial Dermatoses', 'Humans', 'Hyperplasia', 'Male', 'Sebaceous Glands'] | 1,607,487 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.171'], ['C17.800.271'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A10.336.827', 'A17.815.805']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bridging the gender gap: interventions with aggressive girls and their parents. | In response to a gap in gender-sensitive programming for young aggressive girls (5-11) and their families, the SNAP Girls Connection (GC) was developed in 1996. This multi-systemic intervention is built on a developmental model of risk and protective factors within the girl and her relationships. We evaluated the SNAP(... | ['Aggression', 'Child', 'Child Behavior', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Models, Theoretical', 'Parents', 'Sex Factors'] | 20,107,897 | [['F01.145.126.125', 'F01.145.813.045'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['N05.715.350.675', 'N06.850.490.875']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Flour mill lung: a pneumoconiosis of mixed aetiology. | We report two cases of mixed dust fibrosis which occurred in the setting of poorly ventilated flour mills where various kinds of grain, chiefly wheat, were ground using stones whose silica content was analysed to be greater than 80 percent. While one patient was a non-smoker and the other was an ex-smoker, both cooked ... | ['Adult', 'Agriculture', 'Flour', 'Humans', 'Male', 'Pneumoconiosis', 'Silicosis'] | 12,206,482 | [['M01.060.116'], ['J01.040'], ['G07.203.300.484', 'J02.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.483.581', 'C08.381.520.702', 'C24.800'], ['C08.381.483.581.760', 'C08.381.520.702.760', 'C24.800.834']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Plasma kallikrein amidolytic activity in patients with urticaria. | We have studied the plasma kallikrein amidolytic activity in healthy control subjects (inactive), patients with chronic urticaria (active) and patients with acute urticaria (active) from their admission to the emergency room (active) to the time after which their clinical symptomatology had disappeared (inactive). We f... | ['Female', 'Humans', 'Kallikreins', 'Kinetics', 'Male', 'Urticaria'] | 8,281,344 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.959.350.442', 'D12.776.124.125.597', 'D23.119.597'], ['G01.374.661', 'G02.111.490'], ['C17.800.862.945', 'C20.543.480.904']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Follicular lymphoma in situ in the spleen of a patient with autoimmune hemolytic anemia and carrying HCV was associated with more clonal B-cells than t(14;18) positive B-cells. | Certain autoimmune conditions are associated with an increased risk of lymphoid malignancy. We report a 65-year old patient with autoimmune hemolytic anemia (AIHA) complicated by a follicular lymphoma (FL) in situ and other B-cell clones in the spleen. This diagnosis was made by immunohistochemistry, flow cytometry, an... | ['Aged', 'Anemia, Hemolytic, Autoimmune', 'B-Lymphocytes', 'Blotting, Southern', 'Female', 'Flow Cytometry', 'Hepatitis C', 'Humans', 'Immunohistochemistry', 'Lymphoma, Follicular', 'Spleen', 'Splenectomy'] | 28,215,645 | [['M01.060.116.100'], ['C15.378.071.141.125', 'C20.111.175'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.35... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Floating spine after pedicle subtraction osteotomy for post-traumatic kyphosis. | PURPOSE: Pedicle subtraction osteotomy (PSO) was developed to achieve significant correction of a deformity. It was initially used to correct sagittal plane deformities associated with ankylosing spondylitis, but recently it has also been performed in patients with post-traumatic kyphosis. Our aim was to report a case ... | ['Accidental Falls', 'Back Pain', 'Humans', 'Kyphosis', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Osteotomy', 'Radiography', 'Spinal Fusion', 'Thoracic Vertebrae'] | 24,722,882 | [['N06.850.135.122'], ['C23.888.592.612.107'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.800.500'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E04.555.580'], ['E01.370.350.700'], ['E04.555.100.700'], ['A02.835.232.834.892']] | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Proton inhibition of [3H]resiniferatoxin binding to vanilloid (capsaicin) receptors in rat spinal cord. | Protons and capsaicin activate overlapping subsets of sensory nerves by opening ion conductances of similar properties. We have used the [3H]resiniferatoxin binding assay utilizing rat spinal cord membranes to elucidate the possible interaction of protons at the vanilloid (capsaicin) receptor. Using low pH (pH 6.0 and ... | ['Animals', 'Binding, Competitive', 'Capsaicin', 'Diterpenes', 'Dose-Response Relationship, Drug', 'Female', 'Hydrogen-Ion Concentration', 'Protons', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Drug', 'Spinal Cord', 'Time Factors'] | 7,621,890 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['D02.455.849.291'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.300'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations of built environment and proximity of food outlets with weight status: Analysis from 14 cities in 10 countries. | The study aimed to examine associations of neighborhood built environments and proximity of food outlets (BE measures) with body weight status using pooled data from an international study (IPEN Adult). Objective BE measures were calculated using geographic information systems for 10,008 participants (4463 male, 45%) a... | ['Adolescent', 'Adult', 'Body Mass Index', 'Built Environment', 'Cities', 'Cross-Sectional Studies', 'Female', 'Food', 'Geographic Information Systems', 'Humans', 'Internationality', 'Male', 'Middle Aged', 'Obesity', 'Residence Characteristics', 'Restaurants', 'Sex Factors', 'Transportation', 'Young Adult'] | 31,654,731 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['N06.230.145.500'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.300', 'J02.500'], ['L01.313.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Di... | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Correlation between the Length of Ovarian Ligament and Ovarian Torsion: A Prospective Study. | STUDY OBJECTIVE: The study aimed to evaluate whether there is an association between the ovarian ligament length and ovarian torsion.DESIGN: This is a prospective cohort study. Design Classification: II.2.SETTING: The study was conducted in the gynecology department of a university affiliated hospital.INTERVENTION: We ... | ['Adult', 'Female', 'Humans', 'Laparoscopy', 'Ligaments', 'Organ Size', 'Ovarian Diseases', 'Prospective Studies', 'Torsion Abnormality', 'Young Adult'] | 30,071,512 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['A02.513', 'A10.165.669'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['C13.351.500.056.630', 'C19.391.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.65... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metabolic nitrite formation from N-nitrosamines: evidence for a cytochrome P-450 dependent reaction. | Nitrite was formed on incubation of N-nitrosamines with a reconstituted monooxygenase system, consisting of cytochrome P-450 (P-450) and NADPH P-450 reductase from pig liver. Nitrite was not obtained when the nitrosamines were incubated with NADPH P-450 reductase alone or when molecular oxygen or NADPH were omitted. In... | ['Animals', 'Biotransformation', 'Chemical Phenomena', 'Chemistry', 'Cytochrome P-450 Enzyme System', 'Hemoglobins', 'In Vitro Techniques', 'Liver', 'NADPH-Ferrihemoprotein Reductase', 'Nitrites', 'Nitrosamines', 'Oxidation-Reduction', 'Rats', 'Spectrophotometry, Ultraviolet', 'Swine'] | 6,805,975 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['G02'], ['H01.181'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D12.776.124.400', 'D12.776.422.316.762'], ['E05.481'], ['A03.620'], ['D08.811.682.608.191.500'], ['D01.248.497.158.635', 'D01.625.600.600', 'D02.633'], ['D02.654.442'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sociodemographic factors and functional capacity of elderly affected by stroke. | Introduction:: Diseases of old age have shown increasing prevalence in society. One of them is stroke, which can be conceptualized as the interruption of cerebral blood supply due to a leakage or blood vessel obstruction caused by clots.Objective:: To verify the associations between sociodemographic factors and the fun... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Brazil', 'Cross-Sectional Studies', 'Female', 'Geriatric Assessment', 'Humans', 'Male', 'Middle Aged', 'Socioeconomic Factors', 'Stroke'] | 28,513,800 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Post-transfusion platelet responses in critically ill cancer patients with hypoproliferative thrombocytopenia. | BACKGROUND: Platelet transfusion is aimed at increasing platelet counts to prevent or treat bleeding. Critically ill cancer patients with hypoproliferative thrombocytopenia are high consumers of blood products. We herein described their post-transfusion platelet responses in the intensive care unit (ICU) and analyzed t... | ['Aged', 'Critical Illness', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Platelet Transfusion', 'Retrospective Studies', 'Thrombocytopenia'] | 31,724,828 | [['M01.060.116.100'], ['C23.550.291.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01.060.116.630'], ['E02.095.135.140.650'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Recurrent incisional hernia, enterocutaneous fistula and loss of the substance of the abdominal wall: plastic with organic prosthesis, skin graft and VAC therapy. Clinical case. | Surgical wounds dehiscence is a serious post-operatory complication, with an incidence between 0.4% and 3.5%. Mortality is more than 45%. Complex wounds treatment may require a multidisciplinary management. VAC Therapy could be an alternative treatment regarding complex wound. VAC therapy has been recently introduced o... | ['Body Mass Index', 'Collagen', 'Female', 'Hernia, Abdominal', 'Humans', 'Incisional Hernia', 'Intestinal Fistula', 'Middle Aged', 'Negative-Pressure Wound Therapy', 'Obesity', 'Skin Transplantation', 'Surgical Mesh', 'Treatment Outcome'] | 25,953,007 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C23.300.707.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.707.945', 'C23.550.767.500'], ['C06.267.550', 'C06.405.469.471', 'C23.300.575.185.550'], ['M01.060.11... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Microcatheter navigation and thrombolysis in acute symptomatic cervical internal carotid occlusion. | BACKGROUND AND PURPOSE: The treatment of acute stroke distal to an occluded cervical internal carotid artery (ICA) presents a challenge. We report our results of endovascular therapy in 7 patients presenting with acute symptomatic cervical ICA occlusion.PATIENTS AND TECHNIQUES: Among patients presenting with acute stro... | ['Acute Disease', 'Adult', 'Aged', 'Carotid Artery, Internal', 'Carotid Stenosis', 'Catheterization', 'Combined Modality Therapy', 'Equipment Design', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Stroke', 'Thrombolytic Therapy'] | 16,611,763 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.186.200.230'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E02.148', 'E05.157'], ['E02.186'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Platelet-binding immunoglobulins in pregnancy-induced hypertension. I. Platelet-associated IgM on fetal platelets: evidence of a fetal autoimmune reaction? | Pregnancy-induced hypertension (PIH) can be complicated by maternal or fetal thrombocytopenia, or both. In order to investigate possible immunologic causes of these thrombocytopenias, platelet-associated IgG (PAIgG) and IgM (PAIgM) were measured in mothers with PIH and in their infants and compared with those from pati... | ['Autoantibodies', 'Autoimmune Diseases', 'Blood Platelets', 'Female', 'Fetal Blood', 'Humans', 'Hypertension', 'Immunoglobulin G', 'Immunoglobulin M', 'Pregnancy', 'Pregnancy Complications, Cardiovascular', 'Purpura, Thrombocytopenic'] | 3,625,600 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C20.111'], ['A11.118.188', 'A15.145.229.188'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.1... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New Microbial Lineages Capable of Carbon Fixation and Nutrient Cycling in Deep-Sea Sediments of the Northern South China Sea. | Metagenomics of marine sediments has uncovered a broad diversity of new uncultured taxa and provided insights into their metabolic capabilities. Here, we detected microbial lineages from a sediment core near the Jiulong methane reef of the northern South China Sea (at 1,100-m depth). Assembly and binning of the metagen... | ['Archaea', 'Bacteria', 'Carbon Cycle', 'China', 'Genome, Archaeal', 'Genome, Bacterial', 'Metagenome', 'Nutrients', 'Seawater', 'Taiwan'] | 31,126,943 | [['B02'], ['B03'], ['G02.607.125', 'G16.500.150'], ['Z01.252.474.164'], ['G05.360.340.358.050'], ['G05.360.340.358.207'], ['G05.360.340.550'], ['G07.203.300.681', 'J02.500.681'], ['G16.500.275.725.500'], ['Z01.252.474.872', 'Z01.639.850']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Effect of ACE inhibition on pressor, renal vascular, and adrenal responses to infusion of angiotensin I in normal subjects eating a low-salt diet. | To examine the influence of angiotensin-converting enzyme (ACE) on pressor, renal vascular, and adrenal responses during angiotensin I (Ang I) infusion, we studied 10 normotensive, healthy men. Each was in balance with a 10-mEq sodium, 100-mEq potassium intake and was studied before and during ACE inhibition with enala... | ['Adolescent', 'Adrenal Glands', 'Adult', 'Aldosterone', 'Angiotensin I', 'Angiotensin II', 'Angiotensin-Converting Enzyme Inhibitors', 'Blood Pressure', 'Diet, Sodium-Restricted', 'Enalapril', 'Humans', 'Infusions, Intravenous', 'Kidney', 'Male', 'Middle Aged', 'Reference Values', 'Renal Artery', 'Renal Plasma Flow', ... | 10,826,400 | [['M01.060.057'], ['A06.300.071'], ['M01.060.116'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival. | Arginine vasopressin (AVP), a peptide secreted from the posterior pituitary, is chiefly regarded as a hormone involved in the regulation of body fluid balance and osmolality. However, recent evidence has revealed that posterior pituitary hormones can exert important actions on endocrine pancreatic function. In the pres... | ['Animals', 'Apoptosis', 'Arginine Vasopressin', 'Cell Line', 'Glucagon', 'Humans', 'Insulin', 'Insulin-Secreting Cells', 'Mice', 'Receptors, Vasopressin'] | 30,677,431 | [['B01.050'], ['G04.146.954.035'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['A11.251.210'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors affecting the mobilization of primitive and committed hematopoietic progenitors into the peripheral blood of cancer patients. | Rapid hematopoietic reconstitution following peripheral blood progenitor cell (PBPC) autotransplantation is thought to result from reinfusion of committed progenitor cells. This has raised concern that PBPC autografts might be rich in committed hematopoietic progentors responsible for early engraftment, but deficient i... | ['Adult', 'Antigens, CD', 'Antigens, CD34', 'Blood Cells', 'Bone Marrow Cells', 'Bone Marrow Transplantation', 'Breast Neoplasms', 'Cell Separation', 'Combined Modality Therapy', 'Cyclophosphamide', 'Female', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Hematopoiesis', 'Hematopoietic Cell Growth Factors', 'Hema... | 7,536,069 | [['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['A11.118', 'A15.145.229'], ['A11.148', 'A15.378.316'], ['E02.095.147.725.040', 'E04.936.580.040'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E02.186']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Late neuropsychological outcomes in preterm infants of normal IQ: selective vulnerability of the visual system. | Evaluated neuropsychological outcomes in 635 children, ages 7 to 10 years, in relation to birth weight group: < or = 1,000 g; 1,001-1,500 g; 1,501-2,500 g, and > 2,500 g. The prevalence of low IQ (< 85) was related to birth weight. Among children with IQ > 84 (N = 475): (a) Birth weight was unrelated to Verbal IQ, Perf... | ['Child', 'Cognition Disorders', 'Female', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Intelligence', 'Intelligence Tests', 'Male', 'Neuropsychological Tests', 'Retrospective Studies', 'Visual Perception'] | 8,558,374 | [['M01.060.406'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['F01.752.543'], ['F04.711.141.493'], ['F04.711.513'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Myopathy with anti-Jo-1 antibodies: pathology in perimysium and neighbouring muscle fibres. | OBJECTIVE: To evaluate muscle pathology and clinical characteristics in patients with a myopathy and serum antibodies to the Jo-1 antigen (histidyl t-RNA synthetase).BACKGROUND: Anti-Jo-1 antibodies occur in syndromes that may include muscle weakness and pain, Raynaud's phenomenon, interstitial lung disease, arthritis,... | ['Adolescent', 'Adult', 'Autoantibodies', 'Female', 'Histidine-tRNA Ligase', 'Humans', 'Immunohistochemistry', 'Inflammation', 'Male', 'Middle Aged', 'Muscle Fibers, Skeletal', 'Muscular Diseases'] | 10,727,483 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D08.811.464.263.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.58... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Natriuretic peptides maintain sodium homoeostasis during chronic volume loading post-myocardial infarction in sheep. | The impaired ability to excrete sodium is a key feature of established congestive heart failure and is also apparent in asymptomatic left ventricular (LV) impairment. However, few studies have examined responses to chronic volume loading immediately post-myocardial infarction (MI). Experimental MI was induced in six sh... | ['Animals', 'Chronic Disease', 'Cyclic GMP', 'Female', 'Homeostasis', 'Models, Animal', 'Myocardial Infarction', 'Natriuretic Peptide, Brain', 'Sheep', 'Sodium', 'Sodium Chloride', 'Ventricular Dysfunction, Left'] | 12,653,689 | [['B01.050'], ['C23.550.291.500'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['G07.410'], ['E05.598'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776.631.590'], ['B01.05... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Micro-analysis for quinidine in serum by thin-layer chromatography followed by fluorescence densitometry. | We report a thin-layer-chromatographic micro-analysis for quinidine in serum, with detection by fluorescence densitometry. Quinidine is extracted from 20 microL of serum at pH 13 into 3 mL of hexane/acetone solution (80/20 by vol) containing N-(1-naphthyl)ethylenediamine as internal standard. The extract is concentrate... | ['Chromatography, Thin Layer', 'Fluorescence', 'Humans', 'Quinidine', 'Spectrometry, Fluorescence'] | 6,640,909 | [['E05.196.181.400.537'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.206.636', 'D03.605.687.637', 'D03.633.100.810.699'], ['E05.196.712.516.600.676', 'E05.196.867.726']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bevacizumab treatment for acute branch retinal vein occlusion accompanied by subretinal hemorrhage. | PURPOSE: The purpose of this study was to compare the efficacy of intravitreal bevacizumab (IVB) in the treatment of acute (<3 months [mo]. duration) macular edema (ME), with or without subretinal hemorrhage (SRH), resulting from branch retinal vein occlusion (BRVO).MATERIALS AND METHODS: We conducted a retrospective r... | ['Acute Disease', 'Adult', 'Aged', 'Angiogenesis Inhibitors', 'Bevacizumab', 'Female', 'Humans', 'Intravitreal Injections', 'Macular Edema', 'Male', 'Middle Aged', 'Retinal Hemorrhage', 'Retinal Vein Occlusion', 'Retrospective Studies', 'Risk Factors', 'Tomography, Optical Coherence', 'Vascular Endothelial Growth Facto... | 25,330,134 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224.060.375', 'D12.776.124.790.651.114.224.060.438', 'D12.776.377.715.548.114.224.200.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage. | Oxidative DNA damage triggers telomere erosion and cellular senescence. However, how repair is initiated at telomeres is largely unknown. Here, we found unlike PARP1-mediated Poly-ADP-Ribosylation (PARylation) at genomic damage sites, PARylation at telomeres is mainly dependent on tankyrase1 (TNKS1). TNKS1 is recruited... | ['Cell Line', 'Cell Survival', 'DNA Damage', 'DNA Repair', 'Genomic Instability', 'Humans', 'Tankyrases', 'Telomere', 'Telomeric Repeat Binding Protein 1'] | 28,160,604 | [['A11.251.210'], ['G04.346'], ['G05.200'], ['G02.111.222', 'G05.219'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.400.725.115.690.840'], ['A11.284.430.106.279.345.190.160.845', 'G05.360.160.845'], ['D12.776.260.735.750', 'D12.776.660.235.700.750']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Fatal giant cell arteritis with severe bilateral involvement of the vertebral arteries]. | With steroid therapy, it is commonly considered that prognosis is good in giant cell arteritis. However serious or even fatal complications may occur. Here we report the case of a patient who developed fatal giant cell arteritis with severe stenosis of both vertebral arteries and right carotid siphon. Several similar c... | ['Aged', 'Arterial Occlusive Diseases', 'Fatal Outcome', 'Functional Laterality', 'Giant Cell Arteritis', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Spine'] | 17,028,553 | [['M01.060.116.100'], ['C14.907.137'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['F02.830.297.425', 'G11.561.225.425'], ['C10.114.875.700', 'C10.228.140.300.850.500', 'C14.907.253.946.700', 'C14.907.940.090.530', 'C14.907.940.907.700', 'C17.800.86... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes. | OBJECTIVE: To examine the influence of caffeine on the frequency and perception of hypoglycemia in "free-living" patients with type 1 diabetes.RESEARCH DESIGN AND METHODS: A total of 34 patients with type 1 diabetes were recruited for a prospective randomized placebo-controlled double-blind study. After a lead-in phase... | ['Adult', 'Blood Glucose', 'Blood Pressure', 'Caffeine', 'Cerebrovascular Circulation', 'Cognition', 'Cross-Over Studies', 'Diabetes Mellitus, Type 1', 'Double-Blind Method', 'Female', 'Heart Rate', 'Humans', 'Hypoglycemia', 'Male', 'Perception', 'Placebos', 'Sex Characteristics', 'Surveys and Questionnaires'] | 10,857,934 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['G09.330.100.159'], ['F02.463.188'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.370.300... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
SAR for gastro-intestinal absorption and blood-brain barrier permeation of pesticides. | The CORAL software has been applied to the development of classification models for pesticides relative to two pharmacokinetic properties in humans: (i) gastro-intestinal absorption; and (ii) blood-brain barrier permeation. These models were built up using categorical data on pesticide absorption and brain permeation s... | ['Blood-Brain Barrier', 'Gastrointestinal Tract', 'Half-Life', 'Humans', 'Models, Molecular', 'Permeability', 'Pesticides', 'Software', 'Structure-Activity Relationship'] | 29,753,609 | [['A07.035', 'A08.186.211.035'], ['A03.556'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['G02.723'], ['D27.720.031.700', 'D27.888.723'], ['L01.224.900'], ['G02.111.830', 'G07.690.773.997']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vaginal Atrophy in Breast Cancer Survivors: Attitude and Approaches Among Oncologists. | BACKGROUND: Vulvovaginal atrophy (VVA) is a relevant problem for breast cancer survivors (BCSs), in particular for those who receive aromatase inhibitors (AIs). We conducted a survey, to assess the attitude of oncologists toward the diagnosis and treatment of VVA in BCSs.MATERIALS AND METHODS: In 2015, 120 computer-ass... | ['Administration, Intravaginal', 'Antineoplastic Agents', 'Aromatase Inhibitors', 'Atrophy', 'Breast Neoplasms', 'Cancer Survivors', 'Chemotherapy, Adjuvant', 'Clinical Competence', 'Drug Interactions', 'Estrogens', 'Female', 'Gynecology', 'Humans', 'Male', 'Neoplasm Recurrence, Local', 'Oncologists', 'Physician-Patien... | 28,655,486 | [['E02.319.267.120.500'], ['D27.505.954.248'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['C23.300.070'], ['C04.588.180', 'C17.800.090.500'], ['M01.860.350'], ['E02.186.170', 'E02.319.170'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['G07.690.773.968'], ['D27.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Ps... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Precipitating or aggravating factors for headache in patients with major depressive disorder. | OBJECTIVE: The aim of this study was to investigate the common precipitating or aggravating factors for headache among patients with major depressive disorder (MDD) and to compare precipitating or aggravating factors specifically for migraine with those for other headaches.METHODS: Consecutive psychiatric outpatients w... | ['Adaptation, Psychological', 'Adult', 'Demography', 'Depressive Disorder, Major', 'Female', 'Headache', 'Humans', 'Male', 'Periodicity', 'Prevalence', 'Risk Factors', 'Stress, Psychological', 'Surveys and Questionnaires'] | 18,222,138 | [['F01.058'], ['M01.060.116'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['F03.600.300.375'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.645', 'G07.180.562'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Assessment of ground water vulnerability and its application to the development of protection strategy for the water supply aquifer in Owerri, Southeastern Nigeria. | Pollution vulnerability of the Owerri regional water supply aquifer was evaluated as a basis for developing appropriate protection strategy for the groundwater resource. The assessment was accomplished using Legrand, GOD, Siga and DRASTIC models. Techniques of the models generally involved parameters rating and point c... | ['Agriculture', 'Conservation of Natural Resources', 'Fresh Water', 'Geological Phenomena', 'Geology', 'Humans', 'Industry', 'Nigeria', 'Soil', 'Urbanization', 'Waste Management', 'Water Pollution', 'Water Supply'] | 11,334,446 | [['J01.040'], ['J01.256', 'N06.230.080'], ['G16.500.275.280', 'N06.230.232'], ['G01.311'], ['H01.277.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['Z01.058.290.190.565'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['I01.880.853.400.726'], ['N06.850.780.200.800.800.900', 'N06.8... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
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