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Multi-locus variable-number tandem repeat profiling of Salmonella enterica serovar Typhi isolates from blood cultures and gallbladder specimens from Makassar, South-Sulawesi, Indonesia. | Multi-locus variable-number tandem repeat analysis differentiated 297 Salmonella enterica serovar Typhi blood culture isolates from Makassar in 76 genotypes and a single unique S. Typhi genotype was isolated from the cholecystectomy specimens of four patients with cholelithiasis. The high diversity in S. Typhi genotype... | ['Adolescent', 'Adult', 'Aged', 'Bacterial Typing Techniques', 'Cells, Cultured', 'Child', 'Cholecystectomy', 'Cholelithiasis', 'Female', 'Gallbladder', 'Genetic Variation', 'Genotype', 'Humans', 'Indonesia', 'Male', 'Middle Aged', 'Minisatellite Repeats', 'Polymerase Chain Reaction', 'Salmonella typhi', 'Typhoid Fever... | 21,949,819 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['A11.251'], ['M01.060.406'], ['E04.210.120.172'], ['C06.130.409'], ['A03.159.439'], ['G05.365'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['M01.060.116.63... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Carbon dioxide requirement of various species of rumen bacteria. | The carbon dioxide requirement of 32 strains of rumen bacteria, representing 11 different species, was studied in detail. Increasing concentrations of CO(2) were added as NaHCO(3) to a specially prepared CO(2)-free medium which was tubed and inoculated under nitrogen. Prior depletion of CO(2) in the inoculum was found ... | ['Agar', 'Bacteria', 'Bicarbonates', 'Carbon Dioxide', 'Chromatography', 'Cysteine', 'Disaccharides'] | 5,541,030 | [['D09.698.360.041'], ['B03'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.196.181'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D09.698.629.305', 'D09.947.750']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic variation in the purine nucleoside phosphorylase activity of sheep red cells. | The purine nucleoside phosphorylase (NP) activity of sheep red cells was determined by starch gel electrophoresis and by a spectrophotometric assay technique. Some sheep had high activity (NP-high type) and some had low or zero activity (NP-low type). The enzyme deficiency is apparently confined to the red cell since o... | ['Animals', 'Erythrocytes', 'Genes', 'Genetic Variation', 'Goats', 'Kidney', 'Kinetics', 'Lens, Crystalline', 'Liver', 'Lung', 'Myocardium', 'Pentosyltransferases', 'Purine-Nucleoside Phosphorylase', 'Sheep', 'Species Specificity', 'Spleen'] | 826,195 | [['B01.050'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G05.360.340.024.340'], ['G05.365'], ['B01.050.150.900.649.313.500.380.513'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['A09.371.060.500'], ['A03.620'], ['A04.411'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D08.811.913.400.725'], ['D0... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delayed repair of an extensive lip laceration in a colt using an Estlander flap. | A vascularized full-thickness Estlander flap was used to repair a defect involving approximately 40% of the left lower lip of a colt. Postoperative problems were (1) providing nutritional support, (2) minimizing movement at the surgical site, and (3) partial wound dehiscence resulting in a salivary fistula. The surgica... | ['Animals', 'Horses', 'Lip', 'Postoperative Care', 'Surgical Flaps'] | 3,232,331 | [['B01.050'], ['B01.050.150.900.649.313.984.235.472'], ['A01.456.505.631.515', 'A14.549.336'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['A10.850.710', 'E07.862.710']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Idiopathic granulomatous mastitis: A diagnostic and therapeutic challenge. | BACKGROUND: Idiopathic granulomatous mastitis is a rare benign breast disease of women of reproductive age. It usually presents as a painful mass. Since the etiology is unclear, directed diagnosis and management is lacking.METHODS: This is a retrospective chart review of 14 patients, over twelve years (2004-2016), iden... | ['Adrenal Cortex Hormones', 'Adult', 'Biopsy', 'Combined Modality Therapy', 'Diagnostic Imaging', 'Female', 'Granulomatous Mastitis', 'Humans', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Treatment Outcome'] | 28,739,122 | [['D06.472.040'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E02.186'], ['E01.370.350'], ['C13.703.844.603.400', 'C17.800.090.968.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.6... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Squamous cell carcinomas of the eyelids: 18 cases]. | PURPOSE: Squamous cell carcinoma (SCC) is relatively uncommon in eyelid (1 to 2% of all eyelid lesions). The true frequency of this tumor has been difficult to estimate because of a tendency for overdiagnosis (basal cell carcinoma and sebaceous carcinoma) in published reports of eyelids lesions.METHODS: We present a re... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Eyelid Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies'] | 11,151,245 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.443.392.500', 'C11.319.421', 'C11.338.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway. | Unconjugated bilirubin (UCB) is responsible for neonatal jaundice and high level of free bilirubin (Bf) can lead to kernicterus. Previous studies suggest that oxidative stress is a critical component of UCB-induced neurotoxicity. The Nrf2 pathway is a powerful sensor for cellular redox state and is activated directly b... | ['Acetylcysteine', 'Activating Transcription Factor 3', 'Antioxidant Response Elements', 'Antioxidants', 'Apoferritins', 'Bilirubin', 'Cell Line, Tumor', 'Cell Survival', 'Free Radical Scavengers', 'Heme Oxygenase-1', 'Hep G2 Cells', 'Humans', 'MAP Kinase Kinase 1', 'MAP Kinase Kinase 2', 'Mitogen-Activated Protein Kin... | 24,308,969 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['D12.776.260.108.061.875', 'D12.776.930.127.061.875'], ['G02.111.570.080.689.675.700.040', 'G05.360.080.689.675.700.040', 'G05.360.340.024.340.137.750.680.765.040'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D12.776.070.345', 'D12.776.157.427.249.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CyclinPred: a SVM-based method for predicting cyclin protein sequences. | Functional annotation of protein sequences with low similarity to well characterized protein sequences is a major challenge of computational biology in the post genomic era. The cyclin protein family is once such important family of proteins which consists of sequences with low sequence similarity making discovery of n... | ['Artificial Intelligence', 'Computational Biology', 'Cyclins', 'Databases, Protein', 'Predictive Value of Tests', 'Principal Component Analysis', 'Sequence Analysis, Protein'] | 18,596,929 | [['G17.035.250', 'L01.224.050.375'], ['H01.158.273.180', 'L01.313.124'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Transvaginal color Doppler study of blood flow in ectopic pregnancies. | OBJECTIVE: To compare Doppler indices of blood flow in the uterine and spiral arteries and the corpus luteum (CL), in ectopic and intrauterine pregnancies (IUPs).DESIGN: A prospective study of women with an ectopic or singleton IUP at the corresponding stage of gestation.SETTING: The Gynaecological Ultrasound Clinic, K... | ['Female', 'Humans', 'Pregnancy', 'Pregnancy, Ectopic', 'Prospective Studies', 'Reference Values', 'Regional Blood Flow', 'Ultrasonography', 'Uterus', 'Vagina', 'Vascular Resistance'] | 1,730,333 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703.733'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.978.810'], ['G09.330.100.780'], ['E01.370.350.850'], ['A05.360.319.679'], ['A05.360.319.779'], ['G09.330.380.921']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The chloroplast small heat-shock protein oligomer is not phosphorylated and does not dissociate during heat stress in vivo. | Plants synthesize several classes of small (15- to 30-kD monomer) heat-shock proteins (sHSPs) in response to heat stress, including a nuclear-encoded, chloroplast-localized sHSP (HSP21). Cytosolic sHSPs exist as large oligomers (approximately 200-800 kD) composed solely or primarily of sHSPs. Phosphorylation of mammali... | ['Arabidopsis', 'Chloroplasts', 'Escherichia coli', 'Heat-Shock Proteins', 'Heat-Shock Response', 'Hot Temperature', 'Macromolecular Substances', 'Peas', 'Phosphorylation', 'Plant Leaves', 'Plant Proteins', 'Polymers'] | 9,501,148 | [['B01.650.940.800.575.912.250.157.100'], ['A11.284.430.214.190.875.700.140'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.580.216'], ['G07.775.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D05'], [... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Genotoxic and cytotoxic effects of 60Co gamma-rays and 90Sr/90Y beta-rays on Chinese hamster ovary cells (CHO-K1). | Among various types of ionizing radiation, the beta emitter radionuclides are involved in many sectors of human activity, such as nuclear medicine, nuclear industries and biomedicine, with a consequently increased risk of accidental, occupational or therapeutic exposure. Despite their recognized importance, there is li... | ['Animals', 'Apoptosis', 'Beta Particles', 'CHO Cells', 'Cobalt Radioisotopes', 'Cricetinae', 'Dose-Response Relationship, Radiation', 'Female', 'Gamma Rays', 'Necrosis', 'Strontium Radioisotopes'] | 15,138,771 | [['B01.050'], ['G04.146.954.035'], ['G01.750.750.125'], ['A11.251.210.200', 'A11.436.155'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['B01.050.150.900.649.313.992.635.075.250'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Modern scoliosis surgery under the conditions of the German DRG-system]. | In the German health system the payment of a hospital stay is standardised. The common basis is the G-DRG System (German diagnosis-related groups) in which every stay is paid by a lump sum. Scoliosis correction in our times means pedicle screw-based multilevel double rod instrumentation or anterior plate-rod instrument... | ['Diagnosis-Related Groups', 'Germany', 'Health Care Costs', 'Scoliosis', 'Spinal Fusion'] | 19,183,939 | [['N03.219.521.710.305.200.080'], ['Z01.542.315'], ['N03.219.151.400', 'N05.300.375'], ['C05.116.900.800.875'], ['E04.555.100.700']] | ['Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Complex alternative splicing partially inactivates the human chorionic somatomammotropin-like (hCS-L) gene. | The human growth hormone/human chorionic somatomammotropin (hGH/hCS) gene cluster contains five genes: hGH-N, hGH-V, hCS-A, hCS-B, and hCS-L. The expression of the first four genes has been well documented. In contrast, the hCS-L gene has been considered a pseudogene inactivated by loss of the normal intron 2 splice do... | ['Alternative Splicing', 'Animals', 'Base Sequence', 'Cell Line', 'Cloning, Molecular', 'DNA, Complementary', 'Exons', 'Humans', 'Mice', 'Molecular Sequence Data', 'Placental Lactogen', 'Protein Biosynthesis', 'RNA, Messenger', 'Sequence Analysis', 'Transfection'] | 8,083,227 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Non-normal data: Is ANOVA still a valid option? | BACKGROUND: The robustness of F-test to non-normality has been studied from the 1930s through to the present day. However, this extensive body of research has yielded contradictory results, there being evidence both for and against its robustness. This study provides a systematic examination of F-test robustness to vio... | ['Analysis of Variance', 'Monte Carlo Method', 'Sample Size'] | 29,048,317 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E05.318.370.762', 'E05.581.500.902', 'N05.715.360.325.692', 'N06.850.520.445.762']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of estradiol on ischemic factor-induced astrocyte swelling and AQP4 protein abundance. | In the early hours of ischemic stroke, cerebral edema forms as Na, Cl, and water are secreted across the blood-brain barrier (BBB) and astrocytes swell. We have shown previously that ischemic factors, including hypoxia, aglycemia, and arginine vasopressin (AVP), stimulate BBB Na-K-Cl cotransporter (NKCC) and Na/H excha... | ['Animals', 'Aquaporin 4', 'Arginine Vasopressin', 'Astrocytes', 'Blotting, Far-Western', 'Brain Edema', 'Bumetanide', 'Cell Hypoxia', 'Cell Size', 'Cells, Cultured', 'Estradiol', 'Glucose', 'Guanidines', 'Rats', 'Rats, Sprague-Dawley', 'Sodium Potassium Chloride Symporter Inhibitors', 'Sodium-Hydrogen Exchangers', 'So... | 21,471,464 | [['B01.050'], ['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['A08.637.200', 'A11.650.200'], ['E05.196.401.143.500', 'E05.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuropeptide Y expression in Schwann cell precursors. | Some years ago we showed that in the adult rat and mouse neuropeptide Y (NPY) is expressed by olfactory ensheathing cells, a special type of glial cell involved in guiding of the continuously renewing olfactory axons. In the present study, using immunohistochemistry combined with confocal laser scanning microscopy, and... | ['Age Factors', 'Animals', 'Cranial Nerves', 'Female', 'Fetus', 'Ganglia, Spinal', 'Neuropeptide Y', 'Peripheral Nervous System', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Schwann Cells', 'Spinal Nerve Roots', 'Stem Cells', 'Thiolester Hydrolases', 'Ubiquitin Thiolesterase'] | 10,975,912 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['A08.800.800.120'], ['A16.378'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['D12.644.400.500', 'D12.776.631.650.500'], ['A08.800'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.... | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The regional versus national incidence of ectopic pregnancy in Finland from 1966 to 1986. | The annual incidence of ectopic pregnancy (EP) per deliveries, per all diagnosed pregnancies and per female population at fertile age (15-44 years) were measured from 1966 to 1986 in a well-defined urban area of Southwestern Finland, the Turku Region. The incidence rates increased markedly, and were, in the mid-80s, am... | ['Adolescent', 'Adult', 'Female', 'Finland', 'Humans', 'Pregnancy', 'Pregnancy, Ectopic'] | 2,565,257 | [['M01.060.057'], ['M01.060.116'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703.733']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Hypocrellin B-loaded, folate-conjugated polymeric micelle for intraperitoneal targeting of ovarian cancer in vitro and in vivo. | Photodynamic therapy (PDT) is considered an innovative and attractive modality to treat ovarian cancer. In the present study, a biodegradable polymer poly (ethylene glycol) (PEG)-poly (lactic acid)(PLA)-folate (FA-PEG-PLA) was prepared in order to synthesize an active-targeting, water-soluble and pharmacomodulated phot... | ['Animals', 'Cell Line, Tumor', 'Drug Carriers', 'Drug Liberation', 'Female', 'Folic Acid', 'Humans', 'Mice, Nude', 'Micelles', 'Ovarian Neoplasms', 'Perylene', 'Photosensitizing Agents', 'Polyesters', 'Polyethylene Glycols', 'Polymers', 'Quinones', 'Rats, Sprague-Dawley', 'Tissue Distribution', 'Xenograft Model Antitu... | 29,617,063 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D26.255.260', 'E02.319.300.380'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['D03.633.100.733.631.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['D05.374', 'D26.255.560'], ['C04.588.322.455', 'C13... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Value of conventional tomography and computer tomography in therapy-resistant diseases of the paranasal sinuses]. | The informational value of conventional tomography as primary diagnostic method is pointed out in diseases of nasal sinuses resistant to therapy. 5 cases demonstrate the additional information gained by CT-differentiation of soft tissue structures, intraorbital and intracranial expansion. In 78.4% of the examined group... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Child', 'Combined Modality Therapy', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Melanoma', 'Middle Aged', 'Mucocele', 'Nasopharyngeal Neoplasms', 'Orbital Neoplasms', 'Papilloma', 'Paranasal Sinus Neoplasms', 'Polyps', 'Sarco... | 3,775,030 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['M01.060.406'], ['E02.186'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630'], ['C... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Factors inducing retrograde degeneration of the cochlear nerve. | The process of retrograde secondary degeneration is described and its mechanism, discussed. The extent of degeneration following transection of the central or peripheral axon and following various types of damage to the organ of Corti, including the time course of degeneration, is presented in animal experimentation an... | ['Acoustic Stimulation', 'Animals', 'Cats', 'Cochlea', 'Humans', 'Motor Neurons', 'Nerve Degeneration', 'Organ of Corti', 'Retrograde Degeneration', 'Spiral Ganglion', 'Vestibulocochlear Nerve'] | 6,431,887 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A09.246.300.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675.655.500', 'A11.671.655.500'], ['C23.550.737'], ['A09.246.300.246.577'], ['C23.550.737.500'], ['A08.340.390.800', 'A08.800.350.800'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Combined action of anti-arrhythmia agents in the cardiology clinic]. | Results of treatment of 36 patients aged from 25 to 72 years with ventricular extrasystole and paroxysms of atrial fibrillation demonstrated that the absence of contraindications combined treatment with antiarrhythmic drugs is justifiable provided a thorough medical control is performed. | ['Adult', 'Aged', 'Anti-Arrhythmia Agents', 'Cardiomyopathies', 'Chronic Disease', 'Coronary Disease', 'Drug Evaluation', 'Drug Therapy, Combination', 'Heart Valve Diseases', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Rheumatic Heart Disease'] | 3,770,178 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.411.097'], ['C14.280.238'], ['C23.550.291.500'], ['C14.280.647.250', 'C14.907.585.250'], ['E05.290.625', 'E05.337.425'], ['E02.319.310'], ['C14.280.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.507'], ['C01.150.252.410.890... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preliminary evaluation of the learning outcome achieved by a nursing research seminar course for doctoral students. | Educational evaluation is a priority policy of the Ministry of Education and student learning outcome is an important criterion used in educational evaluation work. The purpose of this study was to evaluate the learning outcome of a newly developed course for doctoral students entitled, Nursing Research Seminar. The co... | ['Cross-Sectional Studies', 'Education, Nursing, Graduate', 'Humans', 'Learning', 'Nursing Research', 'Surveys and Questionnaires', 'Taiwan'] | 18,528,815 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I02.358.337.450', 'I02.358.462.565'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The joint impact of smoking and exercise capacity on clinical outcomes among women with suspected myocardial ischemia: the WISE study. | BACKGROUND: Although extensive research has been conducted on both smoking and low exercise capacity alone, few studies have examined the joint impact or interaction of these two risk factors. We examined the joint and interactive effects of smoking and self-reported exercise capacity on subsequent clinical events (hea... | ['Aged', 'Cardiovascular Diseases', 'Exercise', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Middle Aged', 'Myocardial Ischemia', 'Physical Fitness', 'Risk Factors', 'Severity of Illness Index', 'Smoking', 'Survival Analysis'] | 19,361,310 | [['M01.060.116.100'], ['C14'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'],... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Vasopressin and autonomic mechanisms mediate cardiovascular actions of central serotonin. | Intracerebroventricular administration of serotonin (5-HT) to conscious rats increases mean arterial pressure (MAP) and decreases heart rate. To determine the mechanisms involved, 5-HT (2.5 micrograms) was injected intracerebroventricularly into conscious rats pretreated with various neurotransmitter and hormone antago... | ['Animals', 'Autonomic Nervous System', 'Blood Pressure', 'Bradycardia', 'Chlorisondamine', 'Ergolines', 'Heart Rate', 'Hypertension', 'Injections, Intraventricular', 'Male', 'Prazosin', 'Rats', 'Rats, Inbred Strains', 'Serotonin', 'Serotonin Antagonists', 'Vasopressins'] | 2,058,745 | [['B01.050'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.067.319', 'C23.550.073.300'], ['D02.092.877.883.222', 'D02.675.276.200', 'D03.633.100.513.249'], ['D03.132.327.287', 'D03.633.400.439'], ['E01.370.600.875.500', 'G09.330.380.500'], ['C14.907.489'], ['E02.319.267.530.550'], ['D03.633.10... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New method for the experimental evaluation of x-ray grids. | This work describes a new method for the experimental evaluation of antiscatter x-ray grids in radiography. Five commercial grids are evaluated in terms of two parameters which are determined only by the construction of the grid and the x-ray energy. A comparison of the grid performances was made for the x-ray energies... | ['Evaluation Studies as Topic', 'Female', 'Humans', 'Mammography', 'Methods', 'Models, Biological', 'Radiographic Image Enhancement', 'Radiography, Thoracic', 'Technology, Radiologic'] | 683,152 | [['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E05.581'], ['E05.599.395'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600'], ['E01.370.350.700.730'], ['E05.920', 'H02.010.850', 'J01.897.891']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Timely treatment of severe maternal hypertension and reduction in severe maternal morbidity. | OBJECTIVE: To determine if timely treatment within 60 min of confirmed diagnosis of severe maternal hypertension with antihypertensive medications was associated with reduction in severe maternal morbidity.STUDY DESIGN: Medical records of women with severe hypertension (at least two severe blood pressures, systolic ?16... | ['Adult', 'Antihypertensive Agents', 'California', 'Cohort Studies', 'Drug Administration Schedule', 'Female', 'Humans', 'Hypertension, Pregnancy-Induced', "Practice Patterns, Physicians'", 'Pregnancy', 'Prenatal Diagnosis', 'Retrospective Studies', 'Risk', 'Severity of Illness Index', 'Time Factors'] | 30,527,119 | [['M01.060.116'], ['D27.505.954.411.162'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.395', 'C14.907.489.480'], ['N04.590.374.577', 'N05.300.625'], ['G0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Epicardial adipose tissue volume increase in hemodialysis patients treated with sevelamer or calcium-based phosphate binders: a substudy of the Renagel in new dialysis trial. | BACKGROUND: In the general population and in hemodialysis patients epicardial adipose tissue (EAT) has been associated with increased mortality and cardiovascular events. Weight loss and lipid lowering therapies reduced EAT in the general population. It is unknown whether sevelamer, a phosphate (Pi) binder that lowers ... | ['Adipose Tissue', 'Adiposity', 'Adult', 'Aged', 'Biomarkers', 'Calcium Compounds', 'Chelating Agents', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Pericardium', 'Phosphates', 'Renal Dialysis', 'Sevelamer', 'Time Factors', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 27,102,490 | [['A10.165.114'], ['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['D01.146'], ['D27.505.519.914.500', 'D27.720.832.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.1... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of TRPV6 in breast carcinogenesis. | TRPV6 is an endothelial calcium entry channel that is strongly expressed in breast adenocarcinoma tissue. In this study, we further confirmed this observation by analysis of breast cancer tissues, which indicated that TRPV6 mRNA expression was up-regulated between 2-fold and 15-fold compared with the average in normal ... | ['Adenocarcinoma', 'Antineoplastic Agents, Hormonal', 'Breast Neoplasms', 'Calcium', 'Calcium Channel Blockers', 'Calcium Channels', 'Gene Expression Regulation, Neoplastic', 'Humans', 'RNA, Messenger', 'RNA, Small Interfering', 'TRPV Cation Channels', 'Tamoxifen', 'Tumor Cells, Cultured'] | 18,245,667 | [['C04.557.470.200.025'], ['D27.505.954.248.169'], ['C04.588.180', 'C17.800.090.500'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G05.308.370'], ['B01.0... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The distribution of 4-amino-2-phenoxyphenylmethane sulphonamide in the body of warm-blooded animals]. | This study was designed to elucidate the distribution of 4-amino-2-phenoxyphenylmethane sulphonamide in the body of warm-blooded animals (rats) following intragastric administration of this poisonous substance. It was shown that the largest amounts of the unmetabolized parent compound are present in the contents of the... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Eye', 'Intestine, Small', 'Myocardium', 'Rats', 'Spectrophotometry, Ultraviolet', 'Spleen', 'Sulfonamides', 'Tissue Distribution'] | 25,474,917 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['A01.456.505.420', 'A09.371'], ['A03.556.124.684'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.196.712.726.802', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Independent GABAergic and cholinergic modulation of apomorphine-induced stereotyped rearing in the rat. | The injection of GABA into the caudate nucleus inhibited the stereotyped rearing induced by apomorphine in a dose-related manner. Muscimol, a potent GABAergic agonist shared this effect. The inhibitory effect of GABA was easily counteracted by bicuculline but not by pretreatment with atropine. Injection of carbachol in... | ['Animals', 'Apomorphine', 'Atropine', 'Bicuculline', 'Carbachol', 'Caudate Nucleus', 'Female', 'GABA Antagonists', 'Male', 'Muscimol', 'Rats', 'Rats, Inbred Strains', 'Receptors, Cholinergic', 'Receptors, GABA-A', 'Stereotyped Behavior', 'gamma-Aminobutyric Acid'] | 2,836,753 | [['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['D02.092.877.883.333.115', 'D02.675.276.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Type I procollagen gene expression in normal and early healing of the medial collateral and anterior cruciate ligaments in rabbits: an in situ hybridization study. | The purpose of this study was to compare the levels of procollagen type I messenger RNA (mRNA) in normal and healing medial collateral ligament (MCL) and anterior cruciate ligament (ACL) in a rabbit model. Our method of injury involved a surgical model with identical partial lacerations in the midsubstance of the MCL a... | ['Animals', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Collagen', 'DNA Probes', 'Disease Models, Animal', 'Gene Expression', 'Humans', 'Ligaments, Articular', 'Male', 'Nucleic Acid Hybridization', 'Procollagen', 'RNA, Messenger', 'Rabbits', 'Wound Healing'] | 2,010,841 | [['B01.050'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.4... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aortic distensibility and dimensions and the effects of growth hormone treatment in the turner syndrome. | In Turner's syndrome (TS), an increased risk for cardiovascular malformations exists, including aortic dilation of unknown cause. Abnormal biophysical wall properties may play an important role. Magnetic resonance imaging has been successfully used to assess aortic size and wall distensibility. The aim of this study wa... | ['Adolescent', 'Adult', 'Aorta, Thoracic', 'Child', 'Elasticity', 'Follow-Up Studies', 'Human Growth Hormone', 'Humans', 'Magnetic Resonance Angiography', 'Prospective Studies', 'Treatment Outcome', 'Turner Syndrome'] | 16,728,230 | [['M01.060.057'], ['M01.060.116'], ['A07.015.114.056.372'], ['M01.060.406'], ['G01.374.590'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
NMR structure of a human homologous methuselah gene receptor peptide. | Human APG1 gene is homologous to Drosophila methuselah gene associated with extended life span. A peptide (APG1: RNGKRSNRTLREE) corresponding to a predicted region of the intracellular third loop of G protein-coupled receptor coded in human APG1 gene could activate Gi protein alpha subunit directly. The three-dimension... | ['Amino Acid Sequence', 'GTP-Binding Protein alpha Subunits, Gi-Go', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Nuclear Magnetic Resonance, Biomolecular', 'Peptide Fragments', 'Protein Binding', 'Protein Structure, Tertiary', 'Receptors, G-Protein-Coupled'] | 17,109,822 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.277.040.330.300.200.100.200', 'D12.644.360.360.100.200', 'D12.776.157.325.332.100.200', 'D12.776.476.375.100.200', 'D12.776.543.325.100.200'], ['D02.886.765.380', 'D13.695.667.454.504.380', 'D13.695.827.426.504.380', 'D13.695.900.380'], ['B01.050.150.900.649.313.98... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evaluation of clinical prognostic factors for interstitial pneumonia in anti-MDA5 antibody-positive dermatomyositis patients. | OBJECTIVES: We retrospectively investigated clinical prognostic factors for interstitial pneumonia (IP) in anti-melanoma differentiation-associated gene 5 (MDA5) antibody (Ab)-positive dermatomyositis (DM) patients.METHODS: Subjects comprised 18 patients with anti-MDA5 Ab-positive DM-IP (9 survivors; 9 deaths).RESULTS:... | ['Adult', 'Aged', 'Autoantibodies', 'Dermatomyositis', 'Female', 'Humans', 'Interferon-Induced Helicase, IFIH1', 'Lung Diseases, Interstitial', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Survival Rate'] | 28,490,218 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.445.735.720.249.875'], ['C08.381.483'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Visual acuity following treatment of bilateral congenital cataracts. | Several studies have indicated that operation during the first months of life in children with dense congenital cataract improves the final visual acuity. In the current study seven otherwise healthy children operated on before the age of fifty-six days are compared with seven children operated on after the age of thre... | ['Age Factors', 'Cataract', 'Cataract Extraction', 'Child', 'Child, Preschool', 'Contact Lenses', 'Eyeglasses', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Visual Acuity'] | 1,303,856 | [['N05.715.350.075', 'N06.850.490.250'], ['C11.510.245'], ['E04.540.825.249'], ['M01.060.406'], ['M01.060.406.448'], ['E07.632.500.276'], ['E07.632.500.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M0... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Parametrial involvement, regardless of nodal status: a poor prognostic factor for cervical cancer. | OBJECTIVE: To evaluate the effect of resection of central disease when the parametria are involved by tumor in high-risk stage I cervical cancer patients.METHODS: Thirty-two patients with high-risk stage I cervical cancer who underwent radical hysterectomy and had pathologic findings of positive lymph nodes (N = 13), p... | ['Adenocarcinoma', 'Adult', 'Combined Modality Therapy', 'Disease-Free Survival', 'Female', 'Humans', 'Hysterectomy', 'Lymphatic Metastasis', 'Neoplasm Invasiveness', 'Prognosis', 'Regression Analysis', 'Retrospective Studies', 'Risk Factors', 'Time Factors', 'Uterine Cervical Neoplasms'] | 8,677,078 | [['C04.557.470.200.025'], ['M01.060.116'], ['E02.186'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C04.697.650.560', 'C23.550.727.650.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Abuse of the elderly-the hidden agenda. II. Future research and remediation. | A schema for future research and efforts to remediate abuse of the elderly is presented. In the community at large, increased exposure of and education pertaining to the elderly are needed in order to intensify the public/community presence and reduce prejudices. In the medical community, improvements are needed in the... | ['Aged', 'Attitude of Health Personnel', 'Crime', 'Humans', 'Nursing Homes', 'Texas'] | 7,299,008 | [['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['I01.198.240', 'I01.880.735.191'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.825.610'], ['Z01.107.567.875.760.750']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Early postoperative safety and surgical outcomes after implantation of a suprachoroidal micro-stent for the treatment of open-angle glaucoma concomitant with cataract surgery. | PURPOSE: To evaluate the safety of a new suprachoroidal device, the Cypass micro-stent, for the surgical treatment of open-angle glaucoma (OAG) implanted in conjunction with cataract surgery.SETTING: Multicenter clinical study.DESIGN: Prospective interventional case series.METHODS: This is an interim report of an ongoi... | ['Aged', 'Cataract', 'Choroid', 'Female', 'Follow-Up Studies', 'Glaucoma Drainage Implants', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Intraoperative Complications', 'Lens Implantation, Intraocular', 'Male', 'Phacoemulsification', 'Postoperative Complications', 'Postoperative Period', 'Prospective Stud... | 23,506,920 | [['M01.060.116.100'], ['C11.510.245'], ['A09.371.894.223'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.695.250'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['C23.550.505'], ['E04.540.825.600'], ['E04.540.825.249.704', 'E04.94... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Novel control of the position-dependent expression of genes in hepatocytes. The GLUT-1 transporter. | The basal hepatocyte phenotype is conferred by the expression of liver-specific genes. In the adult liver, the basal hepatocyte phenotype is further modified by transcriptional and post-transcriptional regulation of genes which result in the appearance of specific proteins in selected hepatocytes. One of these proteins... | ['Animals', 'Biomarkers', 'Cell Fractionation', 'Cell Separation', 'Cells, Cultured', 'Dactinomycin', 'Gene Expression', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Keratins', 'Liver', 'Liver Circulation', 'Male', 'Membrane Proteins', 'Monosaccharide Transport Proteins', 'RNA, Messenger', 'Rats', 'Rats, Inbred... | 7,690,040 | [['B01.050'], ['D23.101'], ['E05.242.251'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['G05.297'], ['D12.776.580.216.375'], ['D12.776.580.216'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['A03.620'], ['G09.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A method to create reference maps for evaluation of ultrasound images of carotid atherosclerotic plaque. | Ten formalin-fixed atherosclerotic carotid plaques removed by endarterectomy were molded into rectangular agar blocks containing fiducial markers on the top surface. Plaque and fiducial markers were imaged with 3-D multiangle ultrasound (US) spatial compounding as well as planar X ray. Subsequently, the blocks were dec... | ['Arteriosclerosis', 'Calcinosis', 'Carotid Arteries', 'Carotid Stenosis', 'Humans', 'Image Processing, Computer-Assisted', 'Photography', 'Reference Values', 'Reproducibility of Results', 'Ultrasonography'] | 15,550,316 | [['C14.907.137.126'], ['C18.452.174.130'], ['A07.015.114.186'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.600', 'E05.712'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of Major Flavone C-Glycosides and Their Optimized Extraction from Cymbidium kanran Using Deep Eutectic Solvents. | Cymbidium kanran, an orchid exclusively distributed in Northeast Asia, has been highly valued as a decorative plant and traditional herbal medicine. Here, C. kanran extracts were prepared in 70% aqueous methanol using ultrasound-assisted extraction (UAE) and subjected to liquid chromatography-photodiode array detection... | ['Apigenin', 'Flavones', 'Glucosides', 'Glycosides', 'Monosaccharides', 'Orchidaceae', 'Plant Extracts', 'Solvents'] | 29,156,555 | [['D03.383.663.283.266.450.260.110', 'D03.633.100.150.266.450.260.110'], ['D03.383.663.283.266.450.260', 'D03.633.100.150.266.450.260'], ['D09.408.348'], ['D09.408'], ['D09.947.875'], ['B01.650.940.800.575.912.250.618.100.640'], ['D20.215.784.500', 'D26.667'], ['D27.720.844']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transient post-vagotomy dysphagia: A distinct clinical and roentgenographic entity. | Dysphagia is a relatively infrequent complication of vagotomy in the postoperative period. The most common form is a transient post-vagotomy dysphagia which requires not treatment other than the temporary exclusion of solid food. Accurate diagnosis is possible on the basis of clinical history and typical roentgenograph... | ['Adult', 'Aged', 'Barium Sulfate', 'Deglutition Disorders', 'Diagnosis, Differential', 'Esophagus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Vagotomy'] | 1,211,525 | [['M01.060.116'], ['M01.060.116.100'], ['D01.103.075', 'D01.875.800.800.850.075'], ['C06.405.117.119', 'C09.775.174'], ['E01.171'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['E04.525.210.105.600.850']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Permeabilisation of the sarcolemma in mouse diaphragm exposed to Bay K 8644 in vitro: time course, dependence on Ca2+ and effects of enzyme inhibitors. | Treatment of partially depolarised mouse diaphragm muscle in vitro with the Ca2(+)-channel agonist Bay K 8644 (1 microM) induces permeabilisation of the sarcolemma (visualised by penetration of procion yellow). Procion yellow staining was widespread (74% of fibres) after 2 h of treatment, but was negligible after 60 mi... | ['3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester', 'Allopurinol', 'Animals', 'Calcium Channels', 'Cell Membrane Permeability', 'Diaphragm', 'Enzyme Inhibitors', 'Lipoxygenase', 'Masoprocol', 'Mice', 'Phospholipases', 'Quinacrine', 'Triazines'] | 1,692,658 | [['D03.383.725.203.600', 'D03.383.725.547.900'], ['D03.633.100.759.160'], ['B01.050'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G03.143.335', 'G04.175'], ['A02.633.567.900.300'], ['D27.505.519.389'], ['D08.811.682.690.416.583.625', 'D12.776.556.579.374.568.750'], ['D02.455.42... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of synthesis of the neurosecretory egg-laying hormone of Aplysia: antagonistic roles of calcium and cyclic adenosine 3':5'-monophosphate. | The potential role of cyclic nucleotides and calcium as regulators of neuropeptide biosynthesis was examined in the bag cell neurons of Aplysia, which produce and secrete a peptide egg-laying hormone (ELH). Elevated external potassium, which stimulates ELH biosynthesis, increased bag cell cAMP levels when assayed in th... | ['Aplysia', 'Calcium', 'Cyclic AMP', 'Cyclic GMP', 'Invertebrate Hormones', 'Potassium'] | 2,987,435 | [['B01.050.500.644.400.060'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D06.472.445'], ['D01.268.549.550', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Zazen and psychotherapeutic presence. | Zen meditation, or zazen, has attracted the interest of many psychotherapists. The teachings and practices of the Soto Zen tradition are understood as encouraging important areas of both psychological and spiritual development. Zen, like the relational psychoanalytic theories, encourages its practitioners to become awa... | ['Buddhism', 'Humans', 'Meditation', 'Psychotherapy'] | 11,109,137 | [['K01.844.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.374', 'E02.190.901.455', 'F04.754.137.750.500'], ['F04.754']] | ['Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis. | There are currently no effective vaccines for visceral leishmaniasis, the second most deadly parasitic infection in the world. Here, we describe a novel whole-cell vaccine approach using Leishmania infantum chagasi promastigotes treated with the psoralen compound amotosalen (S-59) and low doses of UV A radiation. This ... | ['Animal Structures', 'Animals', 'Anti-Infective Agents, Local', 'Female', 'Furocoumarins', 'Leishmania infantum', 'Leishmaniasis Vaccines', 'Leishmaniasis, Visceral', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'Ultraviolet Rays', 'Vaccines, Inactivated'] | 22,323,556 | [['A13'], ['B01.050'], ['D27.505.954.122.187'], ['D03.383.663.283.446.794', 'D03.633.100.150.446.794', 'D03.633.300.770'], ['B01.268.475.868.488.325'], ['D20.215.894.582.480'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Disseminated encephalomyelitis. A study of 5 cases]. | Five cases of acute disseminated encephalomyelitis (ADE) with a follow-up longer than 5 years are presented. The clinical picture, CT images, MR and laboratory tests, specially LCR and evoked potentials presented in a variable form. In two cases the symptoms were preceded by viral infection. The course was acute in one... | ['Adolescent', 'Adult', 'Brain', 'Brain Diseases', 'Cerebrospinal Fluid', 'Child', 'Diagnosis, Differential', 'Electroencephalography', 'Encephalomyelitis', 'Female', 'Humans', 'Immunoglobulin G', 'Leukocytes', 'Magnetic Resonance Imaging', 'Male', 'Prognosis', 'Radiography', 'Steroids'] | 8,352,977 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['C10.228.140'], ['A12.207.270.210'], ['M01.060.406'], ['E01.171'], ['E01.370.376.300', 'E01.370.405.245'], ['C01.207.291', 'C10.228.228.291', 'C10.228.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vesicoureteral reflux in children with urinary tract infection: comparison of diagnostic accuracy of renal US criteria. | PURPOSE: To directly compare various renal ultrasonography (US) criteria for vesicoureteral reflux (VUR) with voiding cystography, the reference method, for diagnostic accuracy in helping to determine an intermediate strategy of screening children who require cystography.MATERIALS AND METHODS: Institutional review boar... | ['Adolescent', 'Bayes Theorem', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Logistic Models', 'Male', 'Prospective Studies', 'Sensitivity and Specificity', 'Ultrasonography', 'Urinary Tract Infections', 'Vesico-Ureteral Reflux'] | 20,501,726 | [['M01.060.057'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sagittal, vertical, and transverse changes consequent to maxillary molar distalization with the pendulum appliance. | INTRODUCTION: The purpose of this study was to evaluate the skeletal and dental changes in patients who underwent distalization of their maxillary molars with pendulum appliances.METHODS: The sample consisted of 31 patients (initial mean age, 14.58 years) with Angle Class II molar relationships and all permanent teeth ... | ['Adolescent', 'Cephalometry', 'Child', 'Dental Models', 'Female', 'Humans', 'Male', 'Malocclusion, Angle Class II', 'Maxilla', 'Mesial Movement of Teeth', 'Molar', 'Orthodontic Anchorage Procedures', 'Orthodontic Appliances', 'Prospective Studies', 'Tooth Movement Techniques'] | 17,045,150 | [['M01.060.057'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494.630'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['C07.465.714.836.535', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
The anti-inflammatory effects of platinum nanoparticles on the lipopolysaccharide-induced inflammatory response in RAW 264.7 macrophages. | OBJECTIVE: Platinum nanoparticles (nano-Pt) have been reported to possess anti-oxidant and anti-tumor activities. However, the biological activity and mechanism of action of nano-Pt in inflammation are still unknown. The present study was designed to determine the in-vitro anti-inflammatory effects of nano-Pt on lipopo... | ['Animals', 'Anti-Inflammatory Agents', 'Cell Line', 'Cell Survival', 'Cyclooxygenase 2', 'Cytokines', 'Dinoprostone', 'Inflammation', 'Lipopolysaccharides', 'Metal Nanoparticles', 'Mice', 'Mitogen-Activated Protein Kinases', 'NF-kappa B', 'Nitric Oxide Synthase Type II', 'Platinum', 'Proto-Oncogene Proteins c-akt', 'R... | 22,752,115 | [['B01.050'], ['D27.505.954.158'], ['A11.251.210'], ['G04.346'], ['D08.811.600.720.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['C23.550.470'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
CSF tau and tau/Aâ42 predict cognitive decline in Parkinson's disease. | INTRODUCTION: A substantial proportion of patients with Parkinson's disease (PD) have concomitant cognitive dysfunction. Identification of biomarker profiles that predict which PD patients have a greater likelihood for progression of cognitive symptoms is pressingly needed for future treatment and prevention approaches... | ['Adult', 'Aged', 'Amyloid beta-Peptides', 'Antioxidants', 'Apolipoproteins E', 'Cognition Disorders', 'Cohort Studies', 'Cross-Sectional Studies', 'Female', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Monoamine Oxidase Inhibitors', 'Neuropsychological Tests', 'Parkinson Disease', 'Peptide Fragments', 'Predictiv... | 25,596,881 | [['M01.060.116'], ['M01.060.116.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['F03.615.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multiple Rho proteins regulate the subcellular targeting of PAK5. | We investigated the regulatory mechanisms controlling the subcellular localization of p21-activated kinase 5 (PAK5) and found that the Cdc42/Rac interactive binding (CRIB) domain within PAK5 is critical for proper targeting within the cell. We also observed that PAK5 interacts with RhoD and RhoH in addition to Cdc42, a... | ['Cell Line', 'Cell Nucleus', 'Humans', 'Intracellular Space', 'Mitochondria', 'Mutation', 'Protein Binding', 'Protein Structure, Tertiary', 'Protein Transport', 'Protein-Serine-Threonine Kinases', 'Recombinant Fusion Proteins', 'Signal Transduction', 'cdc42 GTP-Binding Protein', 'p21-Activated Kinases', 'rac GTP-Bindi... | 17,064,668 | [['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.082.750', 'A11.284.430'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.365.590'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.610'], ['G03.143.700'], ['D08.811.913.696.620.682.... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The discipline of innovation. | As managers recognize the heightened importance of innovation to competitive success, they face an apparent paradox: the orderly and predictable decisions on which a business rests depend increasingly on the disorderly and unpredictable process of innovation. How can managers expect to plan for--or count on--a process ... | ['Organization and Administration', 'Organizational Innovation', 'United States'] | 10,272,260 | [['N04.452'], ['N04.452.610'], ['Z01.107.567.875']] | ['Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
ENERGY EXPENDITURE IN 21-HYDROXYLASE CONGENITAL ADRENAL HYPERPLASIA PATIENTS AND COMPARISON WITH PREDICTIVE EQUATIONS. | Objective: To characterize resting energy expenditure (REE) in patients with classic 21-hydroxylase congenital adrenal hyperplasia (21-OH CAH) using indirect calorimetry and compare it to the most commonly used REE predictive equations. Methods: This case-control study comprised 29 post-pubertal 21-OH CAH patients regu... | ['Adrenal Hyperplasia, Congenital', 'Basal Metabolism', 'Body Composition', 'Body Mass Index', 'Case-Control Studies', 'Energy Metabolism', 'Humans', 'Steroid 21-Hydroxylase'] | 31,859,548 | [['C12.706.316.090.500', 'C13.351.875.253.090.500', 'C16.131.939.316.129.500', 'C16.320.033', 'C16.320.565.925.249', 'C18.452.648.925.249', 'C19.053.440', 'C19.391.119.090.500'], ['G03.295.154'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.20... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Good practices in free-energy calculations. | As access to computational resources continues to increase, free-energy calculations have emerged as a powerful tool that can play a predictive role in a wide range of research areas. Yet, the reliability of these calculations can often be improved significantly if a number of precepts, or good practices, are followed.... | ['Algorithms', 'Computer Simulation', 'Entropy', 'Mathematics', 'Models, Molecular', 'Models, Theoretical', 'Thermodynamics'] | 20,701,361 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['G01.906.345'], ['H01.548'], ['E05.599.595'], ['E05.599'], ['G01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of functional disability scales and their relevance to radiological progression in patients with rheumatoid arthritis in remission. | OBJECTIVE: To look for any correlations between radiological scores and hand functions evaluated with two different methods in patients with rheumatoid arthritis in remission.METHODS: Forty-two patients diagnosed with rheumatoid arthritis (RA) in remission according to ACR criteria were assessed for their hand function... | ['Arthritis, Rheumatoid', 'Arthrography', 'Disability Evaluation', 'Disease Progression', 'Disease-Free Survival', 'Female', 'Finger Joint', 'Hand', 'Hand Strength', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Remission Induction', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 17,181,923 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E01.370.350.700.070'], ['E01.370.400'], ['C23.550.291.656'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['A02.835.583.405.350'], ['A01... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
What lies ahead for medicine in 1990 and beyond. | Standing on the brink of a new decade, Texas physicians have a lot to look forward to. They also have a lot to worry about. Cancer research may make it possible to intervene in the disease process. At the same time, the Health Care Financing Administration is threatening to tighten its reins on peer review. Expansion o... | ['Economics, Medical', 'Forecasting', 'Legislation as Topic', 'Public Health', 'Texas'] | 2,300,911 | [['N03.219.300'], ['I01.320'], ['N03.706.615'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['Z01.107.567.875.760.750']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Spread of stimulating current in the cortical grey matter of rat visual cortex studied on a new in vitro slice preparation. | Extracellular electrical stimulation of the cortical grey matter is very often used in electrophysiological studies, but the parameters of the stimulation itself have received only little attention. This study addresses the issue of the spread of stimulating current in rat visual areas 17 and 18a maintained in vitro. T... | ['Action Potentials', 'Animals', 'Axons', 'Electric Stimulation', 'Electrophysiology', 'Extracellular Space', 'Female', 'In Vitro Techniques', 'Male', 'Microelectrodes', 'Rats', 'Rats, Sprague-Dawley', 'Rats, Wistar', 'Visual Cortex'] | 8,872,891 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E05.723.402'], ['H01.158.344.528', 'H01.158.782.236'], ['A10.082.500', 'A11.284.295'], ['E05.481'], ['E07.305.250.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the clinico-hematological relevance of the breakpoint location within M-BCR in chronic myeloid leukemia. | The Philadelphia chromosome (Ph) derives from the balanced translocation between chromosomes 9 and 22. This chromosomal translocation results in the fusion between the 5' part of the BCR gene, normally located on chromosome 22, and the 3' part of the ABL gene on chromosome 9 giving origin to a BCR-ABL fusion gene which... | ['Adult', 'Chromosome Breakpoints', 'Female', 'Fusion Proteins, bcr-abl', 'Genes, abl', 'Humans', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Middle Aged', 'Multiplex Polymerase Chain Reaction', 'Reverse Transcriptase Polymerase Chain Reaction'] | 23,269,583 | [['M01.060.116'], ['G05.200.210.170.500'], ['D08.811.913.696.620.682.725.500.500', 'D12.776.602.500.500.100', 'D12.776.624.664.500.100', 'D12.776.624.664.700.171.500'], ['G05.360.340.024.340.375.500.791.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.250', 'C15.378.190.636.370'], ['M01.060.116... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of heme oxygenase and aryl hydrocarbon hydroxylase in the protection by cysteamine from acetaminophen hepatotoxicity. | Administration of cysteamine to rats depressed hepatic aryl hydrocarbon hydroxylase (AHH) activity, cytochrome P-450, and total heme at 24 hr. Total heme remained decreased at 48 hr when all other parameters returned to control values. A significant 5-fold increase in heme oxygenase activity occurred in rat liver 5 hr ... | ['Acetaminophen', 'Animals', 'Aryl Hydrocarbon Hydroxylases', 'Cysteamine', 'Cytochrome P-450 Enzyme Inhibitors', 'Heme Oxygenase (Decyclizing)', 'Liver', 'Male', 'Mixed Function Oxygenases', 'Rats', 'Rats, Inbred Strains'] | 2,609,341 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['B01.050'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['D02.092.471.562.369', 'D02.886.489.472.369'], ['D27.505.389.500', 'D27.505.519.389.335'], ['D08.811.682.690.708.410'], ['A03.620'], ['D08.811.682.690.708'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of individual Ia specificities on T and B cells. I. Studies with mitogen-induced blast cells. | Ia specificities 1-10 were detected on LPS-stimulated splenic lymphocytes and on Con A-stimulated spleen, lymph node, and thymus blasts by direct cytotoxic tests. Since Ia antigens are not readily detectable on resting thymocytes, our results suggest that T cells require some signal before they exhibit full expression ... | ['Animals', 'Antigens', 'B-Lymphocytes', 'Cross Reactions', 'Epitopes', 'Lipopolysaccharides', 'Lymph Nodes', 'Lymphocyte Activation', 'Lymphocytes', 'Mice', 'Mice, Inbred Strains', 'Spleen', 'T-Lymphocytes', 'Thymus Gland'] | 53,267 | [['B01.050'], ['D23.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G12.122.281'], ['D23.050.550'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A10.549.400', 'A15.382.520.604.412'], ['E01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Membrane integrity, mitochondrial activity, ATP content, and motility of the European catfish (Silurus glanis) testicular spermatozoa after freezing with different cryoprotectants. | The extent of cellular damage was investigated after freeze-thawing of the European catfish testicular sperm with various cryoprotectants. The best protection was given by dimethylacetamide (10 and 15%) in a sucrose solution. Under these conditions, the percentage of cells with an intact membrane was high (90%), and th... | ['Acetamides', 'Adenosine Triphosphate', 'Animals', 'Catfishes', 'Cryopreservation', 'Cryoprotective Agents', 'Dimethyl Sulfoxide', 'Freezing', 'Glycerol', 'Male', 'Mitochondria', 'Propylene Glycol', 'Sperm Motility', 'Spermatozoa'] | 10,529,311 | [['D02.065.064', 'D02.241.081.018.110'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['B01.050.150.900.493.080'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['D27.505.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations between genetic polymorphisms of epidermal growth factor receptor (EGFR) and survival of colorectal cancer (CRC) patients treated with 5-fluorouracil-based chemotherapy. | PURPOSE: This retrospective cohort study investigated the association between epidermal growth factor receptor (EGFR) polymorphisms and clinical outcomes in colorectal cancer (CRC) patients treated with 5-fluorouracil (5-FU)-based chemotherapy.METHODS: We genotyped 3 EGFR polymorphisms including R497K, G-216T, and the ... | ['Adjuvants, Immunologic', 'Antimetabolites, Antineoplastic', 'Biomarkers, Tumor', 'Colorectal Neoplasms', 'Drug Combinations', 'ErbB Receptors', 'Female', 'Fluorouracil', 'Follow-Up Studies', 'Humans', 'Levamisole', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Staging', 'Polymorphism, Genetic', 'Prognosis', 'S... | 23,800,895 | [['D27.505.696.477.067'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D23.101.140'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D26.310'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Implementation and evaluation by a population-based RFLP analysis in an urban area, Shinjuku city, Tokyo--the possibility of application for contact investigations]. | OBJECTIVES: The objectives were to examine Mycobacterium tuberculosis transmission patterns by RFLP analysis in Shinjuku city, and to elucidate more effective methods of contact investigations.METHODS: We applied RFLP analysis to 389 M. tuberculosis isolates from 402 TB patients registered in Shinjuku city from Septemb... | ['Adolescent', 'Adult', 'Cluster Analysis', 'Contact Tracing', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mycobacterium tuberculosis', 'Odds Ratio', 'Polymorphism, Restriction Fragment Length', 'Tokyo', 'Transients and Migrants', 'Tuberculosis', 'Urban Population'] | 18,516,901 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.270', 'N06.850.520.270', 'N06.850.780.200.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['E05.318.740.600.600', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Inhibitory effect of diazepam on the activity of the hypothalamic-pituitary-adrenal axis in female rats. | The acute intraperitoneal administration of anxiolytic diazepam (2 mg/kg) inhibits the activity of the hypothalamic-pituitary-adrenal (HPA) axis, i.e., it decreases the concentration of adrenocorticotropic hormone (ACTH) and corticosterone in female rats. This fall of ACTH and corticosterone levels was reversed by an a... | ['Adrenocorticotropic Hormone', 'Animals', 'Bicuculline', 'Corticosterone', 'Depression, Chemical', 'Diazepam', 'Female', 'Flumazenil', 'GABA-A Receptor Antagonists', 'Hypothalamo-Hypophyseal System', 'Isoquinolines', 'Picrotoxin', 'Pituitary-Adrenal System', 'Rats', 'Receptors, GABA-A'] | 8,396,396 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
N-Linked glycans of proteins from mitral valves of normal pigs and pigs affected by endocardiosis. | Endocardiosis, a degenerative and dystrophic process affecting cardiac valves and described in many mammalian species, is characterized by the accumulation of glycosaminoglycans, in particular hyaluronic acid, in the extracellular matrix. The glycoprotein patterns of pig mitral valves in normal animals and animals affe... | ['Animals', 'Carbohydrate Sequence', 'Endocarditis', 'Mitral Valve', 'Polysaccharides', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Swine'] | 10,691,966 | [['B01.050'], ['G02.111.570.160', 'L01.453.245.667.160'], ['C14.280.282'], ['A07.541.510.507'], ['D09.698'], ['E05.196.566.755'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Retinal ganglion cells in the South American opossum (Didelphis aurita). | By using the Golgi technique, the authors investigated the morphology of ganglion cells in the retinas of South American opossums. In flat-mount preparations of the retinas, cell bodies, entire dendritic fields, and the stratification level of ganglion cells were studied. Fractal dimensions of dendritic trees, an objec... | ['Animals', 'Cats', 'Dendrites', 'Fractals', 'Golgi Apparatus', 'In Vitro Techniques', 'Opossums', 'Retinal Ganglion Cells'] | 10,701,444 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['E05.599.125', 'G17.290'], ['A11.284.430.214.190.875.336'], ['E05.481'], ['B01.050.150.900.649.573.575'], ['A08.675.650.850.875', 'A09.371.729.831.875', 'A11.671.650.850.875']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases. | EpCAM (CD326) has diverse roles in cell adhesion and proliferation, and is known to be overexpressed in primary breast carcinomas (PBCs). While clinical and preclinical data suggest a role for EpCAM in metastases, the only prior study of EpCAM expression in breast cancer metastases suggested that EpCAM expression is de... | ['Adult', 'Aged', 'Antigens, Neoplasm', 'Autopsy', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Carcinoma', 'Cell Adhesion Molecules', 'Epithelial Cell Adhesion Molecule', 'Female', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain R... | 20,012,351 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D12.776.395.550.200.263', 'D12.776.543.550.200.263', 'D23.050.285.357'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Discontinuation of oxytocin in the active phase of labor. | OBJECTIVE: To show that early discontinuation of oxytocin will not increase the mean duration of the active labor phase in a clinically significant way.DESIGN: Controlled non-inferiority study.SETTING: Department of Obstetrics and Gynecology, University of Caen, Clemenceau Hospital, France.POPULATION: A total of 138 wo... | ['Adult', 'Delivery, Obstetric', 'Female', 'Heart Rate, Fetal', 'Humans', 'Infant, Newborn', 'Labor, Induced', 'Labor, Obstetric', 'Oxytocics', 'Oxytocin', 'Pregnancy'] | 19,169,930 | [['M01.060.116'], ['E04.520.252'], ['G09.330.380.500.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E04.520.252.968'], ['G08.686.784.769.326'], ['D27.505.696.875.737', 'D27.505.954.705.737'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['G08.686.784.769']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The physico-chemical properties of salmeterol and fluticasone propionate in different solvent environments. | The physico-chemical properties of two anti-asthmatic drugs, salmeterol xinafoate and fluticasone propionate, have been studied in both aqueous and non-aqueous solvent environments. Ultraviolet-visible (UV-Vis) spectroscopy, fluorescence spectroscopy and electrospray ionisation mass spectrometry (ESI-MS) have been used... | ['Albuterol', 'Androstadienes', 'Chlorofluorocarbons, Ethane', 'Chlorofluorocarbons, Methane', 'Fluticasone', 'Mass Spectrometry', 'Methanol', 'Reference Standards', 'Salmeterol Xinafoate', 'Solvents', 'Spectrophotometry, Ultraviolet', 'Water'] | 10,867,258 | [['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['D04.210.500.054.079.129'], ['D02.455.526.439.220.224', 'D02.455.526.510.140.224'], ['D02.455.526.439.220.300', 'D02.455.526.510.140.300'], ['D04.210.500.054.079.129.114'], ['E05.196.566'], ['D02.033.623'], ['E05.978.808'], ['D02.033.100.291.057.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Centrosome isolation from cultured bladder cancer cells--p53 mutation and centrosome hyperamplification]. | Centrosome hyperamplification occurs frequently in human cancers, and is the major contributing factor for chromosomal instability and aneuploidy. We examined centrosome hyperamplification in bladder cancer cell lines. Samples were incubated with antibodies to the centrosome protein gamma-tubulin. The cell line (RT-4),... | ['Centrosome', 'Cyclin E', 'Gene Amplification', 'Humans', 'Mutation', 'Tumor Cells, Cultured', 'Tumor Suppressor Protein p53', 'Ultracentrifugation', 'Urinary Bladder Neoplasms'] | 12,696,185 | [['A11.284.430.214.190.750.585.160', 'A11.284.430.214.190.750.820.500.500'], ['D12.644.360.262.180', 'D12.776.167.218.180', 'D12.776.476.262.180'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['A11.251.860'], ['D12.776.157.687.650', 'D12.776.260.8... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The promise of molecular epidemiology for quantitative risk assessment. | In the long run, molecular epidemiological techniques can provide important insights for understanding a wide variety of important issues in current risk assessment and are applicable across a broad spectrum of adverse effects in addition to carcinogenesis. Unfortunately, current risk assessment practices make very li... | ['Cell Transformation, Neoplastic', 'Disease Susceptibility', 'Epidemiology', 'Humans', 'Neoplasms', 'Oncogenes', 'Risk'] | 3,615,988 | [['C04.697.098.500', 'C23.550.727.098.500'], ['C23.550.291.687', 'G07.100.250'], ['H02.403.720.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['G05.360.340.024.340.375.500'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of synthetic routes to 'Bromo-DragonFLY' and benzodifuranyl isopropylamine homologues utilizing ketone intermediates. Part 1: synthesis of ketone precursors. | Bromo-DragonFLY (BDF) and many of its analogues are misused as recreational drugs due to their potency as psychoactive substances. To date, none of the published routes to these designer amphetamines have exploited a ketone intermediate. It is well known that benzyl methyl ketone (BMK) can be employed as a precursor in... | ['Bromobenzoates', 'Chromatography, Gas', 'Chromatography, High Pressure Liquid', 'Illicit Drugs', 'Ketones', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Propylamines', 'Spectroscopy, Fourier Transform Infrared'] | 23,794,359 | [['D02.241.223.100.150', 'D02.455.426.559.389.127.150'], ['E05.196.181.349'], ['E05.196.181.400.300'], ['D26.878'], ['D02.522'], ['E05.196.867.519'], ['E05.196.566'], ['D02.092.831'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of breed and harvest age on feed intake, growth, carcass traits, blood metabolites, and lipogenic gene expression in Boer and Kiko goats. | The objectives of this experiment were to determine the effects of 2 different breeds (BR), Boer and Kiko, and 4 post-weaning harvest ages (HA; Days 0, 29, 56, and 85) on growth, carcass traits, blood metabolites, and lipogenic gene expression. Forty-eight goat (Capra hircus) kids (BW = 23.9 ± 1.50 kg; 3 to 4 mo) were ... | ['Aging', 'Animals', 'Body Composition', 'Diet', 'Eating', 'Fatty Acids', 'Female', 'Gene Expression Regulation', 'Goats', 'Lipid Metabolism', 'Liver', 'Male'] | 22,287,682 | [['G07.345.124'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['D10.251'], ['G05.308'], ['B01.050.150.900.649.313.500.380.513'], ['G03.458'], ['A03.620']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Impacts of thinning on canopy structure and understory light in secondary poplar-birch forests.] | The variation of forest canopy structure and understory light caused by natural or human disturbances might account for environmental heterogeneity and species diversity in the understory. These factors play an important role in driving the structure, process and pattern in forest ecosystem. We set up two 0.25 hm2 perm... | ['Betula', 'Ecosystem', 'Forestry', 'Forests', 'Populus', 'Trees'] | 31,257,768 | [['B01.650.940.800.575.912.250.859.750.200.750'], ['G16.500.275.157', 'N06.230.124'], ['J01.576.430'], ['G16.500.275.157.437', 'N06.230.124.343'], ['B01.650.940.800.575.912.250.859.797.875.453'], ['B01.650.915']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Disorganisation: a possible cause of apparent conjoint twinning. | A patient with duplications of the internal organs and external structures of the lower half of the body might have traditionally been explained by incomplete twinning. The presence of a fifth digit-like structure protruding from the lower abdomen and facial and cranial abnormalities suggested that, instead, he might b... | ['Abdomen', 'Abnormalities, Multiple', 'Face', 'Humans', 'Leg', 'Male', 'Mutation', 'Skull', 'Twins, Conjoined'] | 1,941,969 | [['A01.923.047'], ['C16.131.077'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['G05.365.590'], ['A02.835.232.781'], ['C16.131.085.806']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Informal field-based learning and work design. | U.S. organizations continue to invest most of their learning budgets in formal training and development programs despite estimates that the majority of learning in the workplace happens informally. In this study we focus on informal field-based learning (IFBL), which represents individuals engaging in self-directed, in... | ['Adult', 'Employment', 'Female', 'Health Personnel', 'Humans', 'Learning', 'Male', 'Middle Aged', 'Professional Competence', 'Work Performance'] | 30,896,189 | [['M01.060.116'], ['N01.824.245'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['M01.060.116.630'], ['I02.399.630'], ['I03.946.675']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[The UN-Convention on the Rights of People with Disabilities and the transition from school to vocational training and career in Germany: public data sources under close scrutiny]. | This paper analyzes public data sources and their requirements for the transition from school to vocational training and career of people with disabilities in the context of Article 31 of the UN-Convention on Rights of People with Disabilities. Different focuses of the public data sources within the involved systems an... | ['Adolescent', 'Databases, Factual', 'Disabled Persons', 'Documentation', 'Electronic Health Records', 'Female', 'Germany', 'Health Transition', 'Humans', 'Male', 'Patient Rights', 'Rehabilitation, Vocational', 'School Health Services', 'United Nations', 'Utilization Review', 'Young Adult'] | 24,217,886 | [['M01.060.057'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['M01.150'], ['L01.453.245'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['Z01.542.315'], ['I01.240.600.400', 'N01.224.625.400', 'N06.850.505.400.700.400', 'N06.85... | ['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Vitamin D status is not associated with inflammatory cytokine levels during experimental human endotoxaemia. | Vitamin D has been shown to modulate innate immune responses in vitro and ex vivo; however, human in-vivo data are lacking. At high latitudes, seasonal vitamin D deficiency is common due to alternating ultraviolet (UV)-B radiation exposure. In the present study, we investigated whether levels of 25 hydroxyvitamin D(3) ... | ['Adult', 'Calcifediol', 'Calcitriol', 'Cytokines', 'Endotoxemia', 'Escherichia coli', 'Humans', 'Immunity, Innate', 'Inflammation Mediators', 'Lipopolysaccharides', 'Male', 'Seasons', 'Vitamin D', 'Young Adult'] | 23,286,950 | [['M01.060.116'], ['D04.210.500.247.222.159.478.250', 'D04.210.500.247.808.146.478.250', 'D04.210.500.812.768.196.478.250', 'D10.570.938.146.478.250'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['D12.644.276.374'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of Intervention by a Palliative Care Team Working in a Japanese General Hospital: A Retrospective Study. | Our objective was to explore the effectiveness of a palliative care team (PCT) by investigating potential differences in opioid prescription between patients who had had PCT involvement before admission to an inpatient hospice and those who had not. A total of 221 patients met the criteria; they were divided into an in... | ['Adult', 'Aged', 'Aged, 80 and over', 'Analgesics, Opioid', 'Drug Utilization Review', 'Female', 'Hospitals, General', 'Humans', 'Inpatients', 'Japan', 'Male', 'Middle Aged', 'Palliative Care', 'Retrospective Studies'] | 24,803,584 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['N04.452.706.477.400', 'N04.761.879.300', 'N05.700.900.300'], ['N02.278.421.389'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Quantitative and comparative assessment of learning in a tongue-operated computer input device--part II: navigation tasks. | Tongue drive system (TDS) is a novel tongue-operated assistive technology (AT) for the mobility impaired, to empower them to access computers and drive powered wheelchairs (PWC) using their free voluntary tongue motion. We have evaluated the TDS performance in five sessions over 5-8 weeks to study the learning process ... | ['Adult', 'Artificial Intelligence', 'Female', 'Humans', 'Magnets', 'Male', 'Motor Activity', 'Self-Help Devices', 'Signal Processing, Computer-Assisted', 'Surveys and Questionnaires', 'Task Performance and Analysis', 'Tongue', 'Wheelchairs'] | 22,692,932 | [['M01.060.116'], ['G17.035.250', 'L01.224.050.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.507'], ['F01.145.632', 'G11.427.410.698'], ['E07.796'], ['L01.224.800'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['A03.556.50... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
[Role of surgery in the treatment of primary gastric lymphoma]. | Primary gastric lymphoma's optimum management remains controversial. We reviewed our series of 23 patients with primary gastric lymphoma treated in our hospital between 1976 and 1998 with surgery as main therapy. Ten patients underwent surgical resection alone, whereas 13 also received postoperative adjuvant therapy, d... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Lymphoma', 'Male', 'Middle Aged', 'Retrospective Studies', 'Stomach Neoplasms'] | 11,341,053 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.4... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Treatment of atypical mycobacterial disease. | The most common disease patterns produced by atypical mycobacteria are pulmonary disease, cervical lymphadenitis, and infection of soft tissue, bones, and joints. The treatment of disease due to atypical mycobacteria can be confusing unless one clearly differentiates the organisms according to clinical characteristics ... | ['Drug Resistance, Microbial', 'Humans', 'Lung Diseases', 'Lymphadenitis', 'Mycobacterium Infections', 'Mycobacterium Infections, Nontuberculous', 'Wound Infection'] | 6,628,016 | [['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['C15.604.315'], ['C01.150.252.410.040.552'], ['C01.150.252.410.040.552.475'], ['C01.947']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of systemic and local CXC chemokine administration on the ethanol-induced suppression of pulmonary neutrophil recruitment. | BACKGROUND: Acute alcohol intoxication impairs the neutrophil response to intrapulmonary infection, resulting in impaired host defense and increased patient morbidity and mortality. We recently showed that intratracheal (IT) chemokine administration promotes pulmonary neutrophil migration in rats and that this process ... | ['Alcoholic Intoxication', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Chemokine CCL4', 'Chemokine CXCL2', 'Chemokines, CXC', 'Dose-Response Relationship, Drug', 'Ethanol', 'Immune Tolerance', 'Intercellular Signaling Peptides and Proteins', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Leukocyte Count', 'Lung', '... | 16,046,875 | [['C25.775.100.175', 'F03.900.100.300'], ['B01.050'], ['E05.927.100.500'], ['D12.644.276.374.200.110.200', 'D12.644.276.374.200.600.200', 'D12.776.467.374.200.110.200', 'D12.776.467.374.200.600.200', 'D23.125.300.110.200', 'D23.125.300.600.750', 'D23.469.200.110.200', 'D23.529.374.200.110.200', 'D23.529.374.200.600.200... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis, characterization, and biocompatibility of a novel biomimetic material based on MGF-Ct24E modified poly(D, L-lactic acid). | Mechano-growth factor (MGF) is an alternative splicing variant of Insulin-like growth factor I. MGF and its 24 amino acid peptide analog corresponding to the unique C-terminal E-domain (MGF-Ct24E) are the positive regulator for tissue regenesis in bone. A novel biomimetic poly(D, L-lactic acid) (PDLLA) modification was... | ['Alkaline Phosphatase', 'Animals', 'Biocompatible Materials', 'Biomimetic Materials', 'Calcium', 'Cell Proliferation', 'Collagen', 'Insulin-Like Growth Factor I', 'Lactic Acid', 'Maleic Anhydrides', 'Materials Testing', 'Osteoblasts', 'Peptides', 'Polyesters', 'Polymers', 'Protein Structure, Tertiary', 'Rats', 'Rats, ... | 22,941,771 | [['D08.811.277.352.650.035'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['J01.637.087'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.161.750', 'G07.345.249.410.750'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
cAMP-independent effects of cholera toxin on B cell activation. III. Cholera toxin A subunit-mediated ADP-ribosylation acts synergistically with ionomycin or IL-4 to induce B cell proliferation. | To investigate whether ADP-ribosylation of proteins by cholera toxin could influence B cell activation, B cells were incubated with the A subunit of cholera toxin. Ionomycin acted synergistically to induce B cell proliferation with the A subunit of cholera toxin but not with cAMP-enhancing agents or with the B subunit ... | ['Adenosine Diphosphate Ribose', 'Animals', 'B-Lymphocytes', 'Calcimycin', 'Cholera Toxin', 'Chromatography, High Pressure Liquid', 'Cyclic AMP', 'Drug Synergism', 'Female', 'Immunologic Deficiency Syndromes', 'Interleukin-4', 'Ionomycin', 'Lymphocyte Activation', 'Male', 'Mice', 'Mice, Inbred CBA', 'Mice, Inbred DBA',... | 7,730,606 | [['D03.633.100.759.646.138.124.070.125', 'D09.408.620.569.070.125', 'D13.695.667.138.124.070.125', 'D13.695.827.068.124.070.125', 'D13.695.827.708.070.125'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D03.633.100.221.173'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of brain nicotinic acetylcholine receptor in centrally administered corticotropin-releasing factor-induced elevation of plasma corticosterone in rats. | The present study was undertaken to clarify the central mechanisms involved in the intracerebroventricularly administered corticotropin-releasing factor-induced elevation of plasma corticosterone in urethane- and alpha-chloralose-anesthetized rats using microdialysis and immunohistochemical techniques. When corticotrop... | ['Adrenal Cortex', 'Adrenergic alpha-Antagonists', 'Animals', 'Brain Chemistry', 'Conotoxins', 'Corticosterone', 'Corticotropin-Releasing Hormone', 'Dopamine beta-Hydroxylase', 'Ganglionic Blockers', 'Gene Expression Regulation', 'Genes, fos', 'Hexamethonium Compounds', 'Hypothalamo-Hypophyseal System', 'Immunohistoche... | 18,423,439 | [['A06.300.071.140'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['B01.050'], ['G02.111.150', 'G03.185'], ['D20.888.590.162', 'D23.946.580.590.162', 'D23.946.833.590.162'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.54... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Framework for Canadian telehealth guidelines: summary of the environmental scan. | A Canadian project (the National Initiative for Telehealth Guidelines) was established to develop telehealth guidelines that would be used by health professionals, by telehealth providers as benchmarks for standards of service and by accrediting agencies for accreditation criteria. An environmental scan was conducted, ... | ['Canada', 'Delivery of Health Care', 'Humans', 'Practice Guidelines as Topic', 'Quality Assurance, Health Care', 'Telemedicine'] | 16,539,751 | [['Z01.107.567.176'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['N04.761.700', 'N05.700'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Interferon-ã and interleukin-4 detected in serum and saliva from patients with oral lichen planus. | Our previous salivary study had demonstrated an apparent T helper 2 (Th2)-predominance in saliva of oral lichen planus (OLP) patients and suggested a potential of salivary interleukin-4 (IL-4) as a biomarker for monitoring disease severity. To further determine the consistency of Th1/Th2 bias of OLP, this study investi... | ['Adult', 'Biomarkers', 'Case-Control Studies', 'Female', 'Humans', 'Interferon-gamma', 'Interleukin-4', 'Lichen Planus, Oral', 'Male', 'Middle Aged', 'Saliva', 'Th1 Cells', 'Th2 Cells'] | 24,158,143 | [['M01.060.116'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling. | BACKGROUND AND PURPOSE: The CB(1) cannabinoid receptor is regulated by its association with membrane microdomains such as lipid rafts. Here, we investigated the role of palmitoylation of the CB(1) receptor by analysing the functional consequences of site-specific mutation of Cys(415) , the likely site of palmitoylation... | ['Animals', 'Cell Line', 'Cell Membrane', 'Cysteine', 'Green Fluorescent Proteins', 'HEK293 Cells', 'Humans', 'Lipoylation', 'Mutation', 'Prosencephalon', 'Rats', 'Receptor, Cannabinoid, CB1', 'Signal Transduction'] | 21,895,628 | [['B01.050'], ['A11.251.210'], ['A11.284.149'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D12.776.532.265'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.540', 'G03.458.875'], ['G05.365.590'], ['A08.186.211.200'], ['B01.050.150.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Reconstruction instead of resection: laminotomy and laminoplasty]. | Spinal instability and deformity have to be kept in mind when performing laminectomies. The procedure described (laminotomy) results in a stable bony reconstruction of the spinal canal, which in addition may be enlarged (laminoplasty): Laminotomy is performed by means of an oscillating saw just medial of the pedicles, ... | ['Adult', 'Aged', 'Astrocytoma', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Hemangioma', 'Hemangiosarcoma', 'Humans', 'Infant', 'Laminectomy', 'Male', 'Meningeal Neoplasms', 'Meningioma', 'Middle Aged', 'Polyradiculopathy', 'Spina Bifida Occulta', 'Spinal Cord Neoplasms'] | 2,293,046 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.557.645.375'], ['C04.557.450.795.390', 'C04.557.645.390... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of salt, smoke, and high pressure on growth of Listeria monocytogenes and spoilage microflora in cold-smoked dolphinfish (Coryphaena hippurus). | The effects of different salting and smoking conditions on the growth of Listeria monocytogenes in cold-smoked dolphinfish (Coryphaena hippurus) fillets were evaluated. High concentrations of phenol (72.47 ppm) and salt (3.25%) in muscle inhibited L. monocytogenes growth in smoked fish stored at 20 degrees C for 4 days... | ['Animals', 'Cold Temperature', 'Colony Count, Microbial', 'Consumer Product Safety', 'Food Handling', 'Food Preservation', 'Food Preservatives', 'Humans', 'Hydrostatic Pressure', 'Listeria monocytogenes', 'Nisin', 'Perciformes', 'Phenol', 'Salts', 'Seafood', 'Smoke', 'Temperature', 'Time Factors'] | 17,340,875 | [['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.850.210'], ['J01.576.423.200'], ['J01.576.423.850.700'], ['D27.720.372.300.385', 'G07.203.300.514.500.700', 'J02.500.51... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Identification and characterization of melatonin binding sites in the gastrointestinal tract of ducks. | Utilizing 2-[125I]iodomelatonin as the radioligand, melatonin binding sites were identified and characterized in the jejunum of ducks. These sites were found to be reversible, saturable, specific and exhibited high affinity for melatonin. Scatchard analyses have established the equilibrium dissociation constant (Kd) fo... | ['Analysis of Variance', 'Animals', 'Binding Sites', 'Binding, Competitive', 'Ducks', 'Indoles', 'Jejunum', 'Kinetics', 'Melatonin', 'Radioligand Assay', 'Subcellular Fractions'] | 1,731,167 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['D03.633.100.473'], ['A03.556.124.684.500', 'A03.556.249.750'], ['G01.374.661', 'G02.111.490'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Localization of five antibiotic resistances at the subunit level in chloroplast ribosomes of Chlamydomonas. | The chloroplast ribosomes from five antibiotic resistant strains of Chlamydomonas, each carrying one mutant gene mapping in chloroplast DNA, have been shown to be resistant to the corresponding antibiotic in a poly(U)-directed amino-acid incorporating assay system. The alteration conferring resistance was localized to ... | ['Chlamydomonas', 'Chloroplasts', 'Clindamycin', 'Cross Reactions', 'Drug Resistance', 'Genes', 'In Vitro Techniques', 'Leucomycins', 'Neomycin', 'Phenylalanine', 'Plant Proteins', 'Ribosomes', 'Spectinomycin', 'Streptomycin'] | 4,275,942 | [['B01.650.940.150.385'], ['A11.284.430.214.190.875.700.140'], ['D03.383.773.532.500.125', 'D09.408.471.500.125'], ['G12.122.281'], ['G07.690.773.984'], ['G05.360.340.024.340'], ['E05.481'], ['D02.540.576.500.999'], ['D09.408.051.623'], ['D12.125.072.050.685', 'D12.125.142.666'], ['D12.776.765'], ['A11.284.430.214.190.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
GABA- and glycine-like immunoreactivity in axons and dendrites contacting the central terminals of rapidly adapting glabrous skin afferents in rat spinal cord. | The object of the present study was to determine the nature and distribution of synaptic contacts on the terminals of rapidly adapting mechanosensory afferents innervating the glabrous skin of the rat foot. Afferents were physiologically characterized by intracellular recording, before injection with neurobiotin and pr... | ['Adaptation, Physiological', 'Animals', 'Axons', 'Dendrites', 'Glycine', 'Immunohistochemistry', 'Lumbosacral Region', 'Mechanoreceptors', 'Microscopy, Electron', 'Nerve Endings', 'Neurons, Afferent', 'Rats', 'Rats, Inbred Strains', 'Skin', 'Spinal Cord', 'Time Factors', 'gamma-Aminobutyric Acid'] | 12,900,920 | [['G07.025', 'G16.012.500'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['D12.125.481'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-collecting a cervico-vaginal specimen for cervical cancer screening: an exploratory study of acceptability among medically underserved women in rural Appalachia. | OBJECTIVE: Innovative screening methods such as self-testing for human papillomavirus (HPV) may alleviate barriers to cervical cancer screening. The purpose of this exploratory study was to determine whether Appalachian Kentucky women would be amenable to self-collecting a cervico-vaginal specimen for HPV testing.METHO... | ['Adult', 'Appalachian Region', 'Early Detection of Cancer', 'Female', 'Humans', 'Kentucky', 'Medically Underserved Area', 'Middle Aged', 'Papillomaviridae', 'Papillomavirus Infections', 'Patient Acceptance of Health Care', 'Rural Population', 'Self-Examination', 'Specimen Handling', 'Uterine Cervical Neoplasms', 'Vagi... | 24,125,753 | [['M01.060.116'], ['Z01.107.567.875.075'], ['E01.390.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.400', 'Z01.107.567.875.510.400'], ['N03.349.650.340', 'N05.300.450.520'], ['M01.060.116.630'], ['B04.280.210.655', 'B04.613.204.655'], ['C01.925.256.650', 'C01.925.928.725'], ['F01.100.150.... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Necrosis of iris and ciliary body--a histopathological study]. | Necrotic foci within the iris and ciliary body were present in 104 eyes examined at the histopathological laboratory of the University Eye Clinic, Hamburg. Three different aetiological mechanisms were found: 1) Vascular acute glaucoma, diminished arterial supply, or radiogenic occlusive vasculitis can lead to ischaemic... | ['Ciliary Body', 'Humans', 'Iris', 'Necrosis'] | 7,173,636 | [['A09.371.060.160', 'A09.371.894.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.450', 'A09.371.894.513'], ['C23.550.717']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell receptor studies on seven cases of diffuse histiocytic malignant lymphoma (reticulum cell sarcoma). | Expression of B and T lymphocyte receptors has been studied in seven cases of reticulum cell sarcoma. In one case, surface receptors and tests of phagocytic function demonstrated the histiocytic origin of the neoplastic cells. In four cases, tumour cells expressed both B and T lymphocyte markers (two cases) or showed a... | ['B-Lymphocytes', 'Cell Membrane', 'Fluorescent Antibody Technique', 'Humans', 'Immune Adherence Reaction', 'Lymph Nodes', 'Lymphoma, Non-Hodgkin', 'Microscopy, Electron', 'Phagocytosis', 'T-Lymphocytes'] | 1,092,721 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.284.149'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Node-positive breast cancer: a comparison of clinical and pathological findings and assessment of axillary clearance. | The Breast Adjuvant Chemotherapy Study of the Anti-Cancer Council of Victoria was set up to encourage the cooperation of clinicians from many centres who are involved in the management of early node-positive breast cancer in Victoria. Data sheets were completed by participants, and an analysis was made of the first 100... | ['Axilla', 'Breast', 'Breast Neoplasms', 'Female', 'Humans', 'Lymph Node Excision', 'Lymph Nodes', 'Lymphatic Metastasis', 'Mastectomy', 'Neoplasm Staging'] | 6,937,174 | [['A01.378.800.090'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E04.466'], ['E01.789.625']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Active Ageing-concept translated to the residential long-term care. | PURPOSE: Active Ageing (AA), as described by the WHO (Active Ageing: a policy framework. World Health Organisation, Geneva 5), is an important concept in gerontology. Since the AA-concept has not been examined in the context of residential long-term care facilities, our study addresses this gap by describing the determ... | ['Aged', 'Aging', 'Child', 'Female', 'Focus Groups', 'Health Status Indicators', 'Homes for the Aged', 'Humans', 'Leisure Activities', 'Long-Term Care', 'Nursing Homes', 'Qualitative Research', 'Quality of Life', 'Research Design', 'Residential Facilities', 'World Health Organization'] | 22,678,352 | [['M01.060.116.100'], ['G07.345.124'], ['M01.060.406'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.450'], ['E02.76... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Humanities [K]'... | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
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