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Pediatric cutaneous angiosarcomas: a clinicopathologic study of 10 cases. | Cutaneous angiosarcomas are rare tumors, which predominantly arise in the sun-exposed skin of the head and neck of adult and elderly patients. Rarely, these tumors can be seen in children. We identified cutaneous angiosarcomas in 10 children and assessed clinical (patient age, tumor site, tumor size, and tumor focality... | ['Adolescent', 'Child', 'Child, Preschool', 'Epithelioid Cells', 'Extremities', 'Female', 'Hemangiosarcoma', 'Humans', 'Immunohistochemistry', 'Infant', 'Male', 'Mitosis', 'Necrosis', 'Skin Neoplasms', 'Time Factors', 'Treatment Outcome'] | 21,164,289 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['A11.329.372.300', 'A11.627.482.300', 'A11.733.397.300', 'A15.382.670.522.300', 'A15.382.680.397.300'], ['A01.378'], ['C04.557.450.795.390', 'C04.557.645.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512'... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
AZGP-1 immunohistochemical marker in prostate cancer: potential predictive marker of biochemical recurrence in post radical prostatectomy specimens. | One of the major challenges in prostate cancer research is to identify prognostic/predictive factors to distinguish aggressive disease from indolent one. To select prognostic/predictive markers of postoperative biochemical recurrence (BCR) that could be easily performed in daily pathology practice, the expression of 6 ... | ['Adipokines', 'Adult', 'Aged', 'Cadherins', 'Carrier Proteins', 'Glycoproteins', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Mucin-1', 'Neoplasm Proteins', 'Prostatectomy', 'Prostatic Neoplasms', 'Retrospective Studies', 'Trans-Activators', 'Transcriptional Regulator ERG', 'Vimentin'] | 24,508,823 | [['D06.472.699.042', 'D12.644.276.024', 'D12.644.548.011', 'D12.776.467.024', 'D23.529.024'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['D12.776.157'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.2... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Alteration of sensitivity of intratumor quiescent and total cells to gamma-rays following thermal neutron irradiation with or without 10B-compound. | PURPOSE: Changes in the sensitivity of intratumor quiescent (Q) and total cells to gamma-rays following thermal neutron irradiation with or without 10B-compound were examined.METHODS AND MATERIALS: 5-Bromo-2'-deoxyuridine (BrdU) was injected to SCC VII tumor-bearing mice intraperitoneally 10 times to label all the prol... | ['Animals', 'Boron Neutron Capture Therapy', 'Bromodeoxyuridine', 'Carcinoma, Squamous Cell', 'Cell Division', 'Dose-Response Relationship, Radiation', 'Female', 'Gamma Rays', 'Mice', 'Mice, Inbred C3H', 'Micronucleus Tests', 'Neoplasms, Experimental', 'Radiation Tolerance', 'Radiation-Sensitizing Agents', 'Radiobiolog... | 10,701,745 | [['B01.050'], ['E02.815.722.500.100'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of the state of body fluids in anuric hyperglycemic humans. | Based on mathematical analysis, a method computing deviations from normal in body weight, water and sodium, and requiring only presenting body weight and hyperglycemic and euglycemic plasma glucose and sodium concentrations in anuria was developed. Data from 18 hyperglycemic episodes (12 anuric patients) treated with i... | ['Anuria', 'Blood Glucose', 'Body Fluids', 'Body Water', 'Extracellular Space', 'Humans', 'Hyperglycemia', 'Intracellular Fluid', 'Osmolar Concentration'] | 3,696,091 | [['C12.777.419.078', 'C12.777.934.141', 'C13.351.968.419.078', 'C13.351.968.934.070'], ['D09.947.875.359.448.500'], ['A12.207'], ['A12.207.200'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['A11.284.430.429', 'A11.284.835.450', 'A12.207.515'], ['G02.640']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The deep inferior epigastric artery free skin flap: anatomic study and clinical application. | We carried out an anatomic study to create the efficient surgical technique of elevating the inferior epigastric artery free skin flap. The deep inferior epigastric artery bifurcates into the lateral and medial branches. The former usually is larger in diameter and has many skin perforators slightly lateral to the midl... | ['Abdominal Muscles', 'Adult', 'Arteries', 'Child', 'Dermatologic Surgical Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Skin', 'Surgical Flaps'] | 8,460,189 | [['A02.633.567.050'], ['M01.060.116'], ['A07.015.114'], ['M01.060.406'], ['E04.680.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A17.815'], ['A10.850.710', 'E07.862.710']] | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Correlation of apparent molecular weight and antigenicity of viral proteins: an SDS-page separation followed by acrylamide-agarose electrophoresis and immunoprecipitation. | A simple method is described which combines a sodium dodecyl sulfate polyacrylamide gel electrophoresis (SOS-PAGE) in the first demension with a second electrophoresis, at right angles to the first, into an agarose matrix. The proteins, separated by SDS-PAGE, are exposed to appropriate antisera after the second stage e... | ['Antigens, Viral', 'Avian Myeloblastosis Virus', 'Avian Sarcoma Viruses', 'Chemical Precipitation', 'Electrophoresis, Agar Gel', 'Electrophoresis, Polyacrylamide Gel', 'Friend murine leukemia virus', 'Immunologic Techniques', 'Molecular Weight', 'Sodium Dodecyl Sulfate', 'Viral Proteins'] | 190,321 | [['D23.050.327'], ['B04.613.807.070.110', 'B04.820.650.070.110'], ['B04.613.807.070.120', 'B04.820.650.070.120'], ['E05.196.150', 'G02.159'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.196.401.402', 'E05.301.300.319'], ['B04.613.807.375.525.225', 'B04.820.650.375.525.225'], ['E05.478'], ['G02.494'], ['D02.033.415.22... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nitric oxide accelerates seed germination in warm-season grasses. | The nitric oxide (NO) donor sodium nitroprusside (SNP) significantly promoted germination of switchgrass (Panicum virgatum L. cv Kanlow) in the light and in the dark at 25 degrees C, across a broad range of concentrations. SNP also promoted seed germination in two other warm-season grasses. A chemical scavenger of NO i... | ['Abscisic Acid', 'Catechin', 'Cotyledon', 'Cyclic N-Oxides', 'Ferricyanides', 'Ferrocyanides', 'Free Radical Scavengers', 'Germination', 'Imidazoles', 'Light', 'Nitric Oxide', 'Nitric Oxide Donors', 'Nitrites', 'Nitroprusside', 'Panicum', 'Poaceae', 'Seasons', 'Seeds', 'Temperature'] | 16,369,800 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['A18.024.500.750.333', 'A18.024.875.500'], ['D03.661.24... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Blood lactate thresholds and walking/running economy are determinants of backpack-running performance in trained soldiers. | We developed a standardized laboratory treadmill protocol for assessing physiological responses to a simulated backpack load-carriage task in trained soldiers, and assessed the efficacy of blood lactate thresholds (LTs) and economy in predicting future backpack running success over an 8-mile course in field conditions.... | ['Adult', 'Anaerobic Threshold', 'Exercise Test', 'Humans', 'Lactic Acid', 'Male', 'Military Personnel', 'Physical Exertion', 'Running', 'United Kingdom', 'Walking', 'Weight-Bearing', 'Young Adult'] | 27,154,276 | [['M01.060.116'], ['G03.680.110', 'G11.427.680.134'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['M01.526.625'], ['G11.427.683'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['Z01... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Experimental verification of effectiveness and harmlessness of the Qigong maneuver. | A series of experiments involving the Qigong (Q-G) maneuver were conducted after our preliminary studies in 1986. Eighteen active fighter pilots served as subjects. After mastery of the Q-G maneuver in 5-7 sessions of training, tests at +1 Gz further verified that the blood pressure raising effect of this maneuver has ... | ['Adult', 'Aerospace Medicine', 'Blood Pressure', 'Breathing Exercises', 'Electroencephalography', 'Gravitation', 'Heart Rate', 'Humans', 'Hyperventilation', 'Male', 'Muscle Contraction', 'Oxygen Consumption', 'Physical Endurance', 'Reference Values', 'Respiration'] | 1,996,931 | [['M01.060.116'], ['H02.403.029'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E02.190.525.186', 'E02.779.474.124'], ['E01.370.376.300', 'E01.370.405.245'], ['G01.060.350'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.618.501', 'C23.888.852.591'], ['G11.427.494']... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
[Expression and hypoxic regulation of vascular endothelial growth factor and matrix metalloproteinase-9 in esophageal carcinoma]. | OBJECTIVE: To investigate the the expression and hypoxic regulation of vascular endothelial growth factor(VEGF) and matrix metalloproteinase-9.METHODS: VEGF mRNA and MMP-9 mRNA were examined by reverse transcription-polymerase chain reaction (RT-PCR) in 43 esophageal carcinoma specimens including 18 para-tumorous esoph... | ['Endothelial Growth Factors', 'Esophageal Neoplasms', 'Female', 'Gene Expression Regulation', 'Humans', 'Hypoxia', 'Lymphokines', 'Male', 'Matrix Metalloproteinase 9', 'Middle Aged', 'Oxygen', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Vascular Endothelial Growth Factor A', 'Vascular Endothe... | 11,977,637 | [['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['D12.644.276.374.480', 'D12.776.467.374.480', 'D23.529.374.480'], ['D08.811.277... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Improved FcãRIIb targeting functionally translates into enhanced inhibition of basophil activation. | BACKGROUND: Mast cells and basophils express the high-affinity IgE receptor, FcåRI, as well as the low-affinity IgG receptor, FcãRIIb. While FcåRI is responsible for IgE-dependent degranulation upon coaggregation with allergens, FcãRIIb has been shown to downregulate degranulation through cross-linking with FcåRI. A pr... | ['Antibody Affinity', 'Basophils', 'Cell Degranulation', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoglobulin E', 'Receptors, IgE', 'Receptors, IgG', 'Recombinant Fusion Proteins'] | 24,557,487 | [['G12.040', 'G12.122.125'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['G04.468.160'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The appreciation of affect in alcoholic Korsakoff patients. | The purpose of this study is to assess the appreciation of affective components of words in patients with insult to diencephalic and subcortical brain structures thought to subserve emotional expression. Six alcoholic Korsakoff patients were presented with triadic comparisons composed of names of birds, predators, and ... | ['Adult', 'Affect', 'Alcohol Amnestic Disorder', 'Humans', 'Male', 'Middle Aged', 'Word Association Tests'] | 3,744,704 | [['M01.060.116'], ['F01.470.047'], ['C10.720.112.100', 'C25.723.705.150.100', 'C25.775.100.087.193.100', 'F03.900.100.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.647.905']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Surgical treatment of postop large size abdominal hernia in patients with obesity]. | There were 140 patients with morbid obesity operated on for postoperative abdominal hernia. In 2 (1.4%) patients an acute cardiopulmonary insufficiency occurred, and in another 2 (1.4%) an acute thrombophlebitis of the lower extremities veins. Two patients died. The hernia recurrence have occurred in 3 (2.1%) patients ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Hernia, Ventral', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Postoperative Complications', 'Retrospective Studies'] | 10,370,314 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.707.374.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gestational exposure to persistent organic pollutants: maternal liver residues, pregnancy outcome, and effects on hepatic gene expression profiles in the dam and fetus. | Dietary exposure of Inuit people to a mixture of pesticides and polychlorinated biphenyls, or persistent organic pollutants (POPs), during pregnancy is a public health concern. We examined the consequences of administering the mixture of 28 POPs found in the Inuit diet (at doses representing 10-1000 times dietary level... | ['Administration, Oral', 'Animals', 'Diet', 'Environmental Pollutants', 'Female', 'Fetus', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Hydrocarbons, Chlorinated', 'Insecticides', 'Inuits', 'Liver', 'Male', 'Pregnancy', 'Pregnancy, Animal', 'RNA, Messenger', 'Rats'] | 12,655,031 | [['E02.319.267.100'], ['B01.050'], ['G07.203.650.240'], ['D27.888.284'], ['A16.378'], ['E05.393.332'], ['G05.308'], ['D02.455.526.439'], ['D27.720.031.700.491', 'D27.888.723.491'], ['M01.686.508.150.600.375.500', 'M01.686.508.150.675', 'M01.686.754.254.500.500'], ['A03.620'], ['G08.686.784.769'], ['G08.686.784.769.498'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Artificial intelligence models to predict acute phytotoxicity in petroleum contaminated soils. | Environment pollutants, especially those from total petroleum hydrocarbons (TPH), have a highly complex chemical, biological and physical impact on soils. Here we study this influence via modelling the TPH acute phytotoxicity effects on eleven samples of soils from Sakhalin island in greenhouse conditions. The soils we... | ['Artificial Intelligence', 'Hordeum', 'Hydrocarbons', 'Islands', 'Models, Theoretical', 'Neural Networks, Computer', 'Petroleum', 'Russia', 'Soil', 'Soil Microbiology', 'Soil Pollutants'] | 32,163,774 | [['G17.035.250', 'L01.224.050.375'], ['B01.650.940.800.575.912.250.822.481'], ['D02.455'], ['G16.500.275.505', 'N06.230.295', 'Z01.639'], ['E05.599'], ['G17.485', 'L01.224.050.375.605'], ['D20.345.630', 'N06.230.132.258.630'], ['Z01.252.122.500', 'Z01.542.248.775'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.23... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Role of proximal convoluted tubule in pressure diuresis in the rat. | The role of different nephron segments in the diuretic response to acute arterial hypertension was studied with tubular microperfusion. Early proximal convolutes were perfused with synthetic glomerular ultrafiltrate; fluid was collected from the last visible loop of the same proximal or from the first loop of the dista... | ['Absorption', 'Animals', 'Blood Pressure', 'Body Fluids', 'Chlorides', 'Diuresis', 'Glomerular Filtration Rate', 'Homeostasis', 'Hypertension', 'Kidney Tubules, Proximal', 'Male', 'Osmolar Concentration', 'Rats', 'Rats, Inbred Strains', 'Renal Circulation'] | 3,740,275 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A12.207'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G08.852.179'], ['E01.370.390.400.300', 'G08.852.357'], ['G07.410'], ['C14.907.489'], ['A05.810.453.736.560.570'], ['G02.640'], ['B01.0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of macrolide resistance in Bordetella bronchiseptica is associated with the loss of virulence. | Background: Why resistance to specific antibiotics emerges and spreads rapidly in some bacteria confronting these drugs but not others remains a mystery. Resistance to erythromycin in the respiratory pathogens Staphylococcus aureus and Streptococcus pneumoniae emerged rapidly and increased problematically. However, res... | ['Animals', 'Anti-Bacterial Agents', 'Bacterial Adhesion', 'Bacterial Toxins', 'Bordetella Infections', 'Bordetella bronchiseptica', 'Cell Survival', 'Cytokines', 'Disease Models, Animal', 'Drug Resistance, Bacterial', 'Erythromycin', 'Mice', 'Mutation', 'Selection, Genetic', 'Serial Passage', 'Virulence'] | 30,107,601 | [['B01.050'], ['D27.505.954.122.085'], ['G06.099.050'], ['D23.946.123'], ['C01.150.252.400.143'], ['B03.440.400.425.115.425.050', 'B03.660.075.090.344.425.050'], ['G04.346'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G06.099.225', 'G06.225.347', 'G07.690.773... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A double-blind switch study of paroxetine and venlafaxine in obsessive-compulsive disorder. | BACKGROUND: The treatment guidelines for obsessive-compulsive disorder (OCD) propose to switch serotonin reuptake inhibitors (SRIs) in case of refractoriness. However, no controlled research has been published yet that prospectively examined the effects of changing SRIs. This article describes the first double-blind sw... | ['Administration, Oral', 'Adult', 'Antidepressive Agents, Second-Generation', 'Cross-Over Studies', 'Cyclohexanols', 'Double-Blind Method', 'Drug Resistance', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obsessive-Compulsive Disorder', 'Paroxetine', 'Severity of Illness Index', 'Treatment Outcome', 'Venlafaxine Hydrochl... | 14,744,166 | [['E02.319.267.100'], ['M01.060.116'], ['D27.505.954.427.700.122.050'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G07.690.773.984'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The effect of space flight factors on the peripheral blood in the newt Pleurodeles waltlii]. | The effects of space flight factors (SFF) on the peripheral blood in Pleurodeles waltlii were assessed after 12-day flight on board of the biosatellite "Kosmos-2229". These animals were also used to study regeneration of the limb, tail and lens. The corresponding control groups of animals allowed to distinguish between... | ['Animals', 'Blood Cells', 'DNA', 'Female', 'Forelimb', 'Hematopoiesis', 'Lens, Crystalline', 'Pleurodeles', 'Regeneration', 'Russia', 'Space Flight', 'Tail', 'Time Factors'] | 7,987,203 | [['B01.050'], ['A11.118', 'A15.145.229'], ['D13.444.308'], ['A13.395'], ['G04.152.825', 'G09.188.343'], ['A09.371.060.500'], ['B01.050.150.900.090.608.700.540'], ['G16.762'], ['Z01.252.122.500', 'Z01.542.248.775'], ['J01.937.285.850'], ['A13.895'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Evolutionary Expression of HER2 Conferred by Chromosome Aneuploidy on Circulating Gastric Cancer Cells Contributes to Developing Targeted and Chemotherapeutic Resistance. | Purpose: Previous human epidermal growth factor receptor-2 (HER2)-derived resistance studies were based on ex vivo models, which could not mirror evolutionary expression of HER2 during therapy. To investigate dynamic expression of HER2 and its contribution to developing therapeutic resistance conferred by chromosome an... | ['Aneuploidy', 'Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Chromosomes, Human, Pair 8', 'Drug Resistance, Neoplasm', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization, Flu... | 30,012,565 | [['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['G07.690.773.984.395'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', ... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Alginate-chaperoned facile refolding of Chromobacterium viscosum lipase. | Urea denatured lipase from Chromobacterium viscosum lipase could be refolded by addition of alginate with high guluronic acid content. The refolded molecule could be recovered by affinity precipitation. This approach resulted in recovery of 80% (of original activity) as compared to classical dilution method which gave ... | ['Alginates', 'Animals', 'Chromobacterium', 'Glucuronic Acid', 'Hexuronic Acids', 'Lipase', 'Pancreas', 'Protein Denaturation', 'Protein Folding', 'Spectrometry, Fluorescence', 'Swine', 'Triticum'] | 16,624,637 | [['D09.698.068'], ['B01.050'], ['B03.440.450.360', 'B03.660.075.525.100'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.241.511.902.915.400', 'D09.811.922.400'], ['D08.811.277.352.100.400'], ['A0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The application of plasma tartrate-resistant acid phosphatase to assess changes in bone resorption in response to artificial menopause and its treatment with estrogen or norethisterone. | Plasma tartrate-resistant acid phosphatase (TR ACP), urinary hydroxyproline excretion (UH), serum osteocalcin, and bone alkaline phosphatase isozyme were determined in a prospective study in 31 women who had undergone bilateral ovariectomy (OOX). Nine patients were followed up for 1 year without treatment and for the f... | ['Acid Phosphatase', 'Adult', 'Bone Resorption', 'Drug Resistance', 'Estrogens', 'Female', 'Humans', 'Menopause', 'Middle Aged', 'Norethindrone', 'Ovariectomy', 'Tartrates'] | 2,509,014 | [['D08.811.277.352.650.025'], ['M01.060.116'], ['C05.116.264', 'G11.427.213.150'], ['G07.690.773.984'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.157.500', 'G08.686.841.249.500'], ['M01.060.116.630'], ['D04.210.500.668.651.693.651'], ['E04.270.282.685', 'E04.950.165.685', '... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Clinical effect of human fibroblast interferon on malignant cancer. (2) Immunological study of the patients under treatment]. | Several immunological studies were performed in patients with various malignant diseases under treatment of human fibroblast interferon (HFIF). Lymphocyte natural killer (NK) activity against culture cell lines was measured before and at various time after HFIF treatment. The majority of patients reached the highest le... | ['Cytotoxicity, Immunologic', 'Humans', 'Hypersensitivity, Delayed', 'Interferon Type I', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Lymphocytes', 'Neoplasms'] | 7,184,400 | [['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.418'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visual and portable strategy for copper(II) detection based on a striplike poly(thymine)-caged and microwell-printed hydrogel. | Due to its importance to develop strategies for copper(II) (Cu(2+)) detection, we here report a visual and portable strategy for Cu(2+) detection based on designing and using a strip-like hydrogel. The hydrogel is functionalized through caging poly(thymine) as probes, which can effectively template the formation of flu... | ['Copper', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Poly T'] | 25,325,821 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.033.455.250.700.485', 'D05.750.219.500', 'D05.750.741.485', 'D20.280.320.609.500', 'D25.720.532.500', 'D25.720.741.485', 'D26.255.165.320.375.375', 'J01.637.051.720.584.500', 'J01.637.051.720.741.485'], ['D13.695.578.500.600']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Animal experiment, pharmacokinetic and clinical studies of intraperitoneal therapy with interleukin-2 (n Il-2) in patients with ovarian carcinoma]. | OBJECTIVE: In an orthotopic transplantation model using human ovarian cancer xenografts we evaluated antitumor effects of nIL-2 as well as its side effects in a clinical phase I/II study.METHODS: In patients with advanced ovarian cancer nIL-2 was administered i.p. in escalating doses every two days by means of a Tenckh... | ['Adult', 'Animals', 'Chemotherapy, Cancer, Regional Perfusion', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Humans', 'Immune Tolerance', 'Immunity, Cellular', 'Injections, Intraperitoneal', 'Interleukin-2', 'Middle Aged', 'Neoplasm Transplantation', 'Ovarian Neoplasms'] | 8,672,926 | [['M01.060.116'], ['B01.050'], ['E02.319.267.200', 'E04.292.425'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'], ['G12.450.050.400'], ['E02.319.267.530.490'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reduced catheter sepsis and prolonged catheter life using a tunnelled silicone rubber catheter for total parenteral nutrition. | One hundred and five patients were given total parenteral nutrition (TPN) for an average of 15 days via centrally placed venous catheters. Thirty-seven polyvinyl chloride (PVC) and 80 silicone rubber catheters were used. All the silicone rubber and 8 of the PVC catheters were buried in a subcutaneous tunnel. When silic... | ['Catheterization', 'Humans', 'Parenteral Nutrition', 'Parenteral Nutrition, Total', 'Polyvinyl Chloride', 'Prospective Studies', 'Silicone Elastomers', 'Staphylococcal Infections'] | 6,809,094 | [['E02.148', 'E05.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.421.505', 'E02.642.500.505'], ['E02.421.505.575', 'E02.642.500.505.750'], ['D02.455.326.271.884.533.565', 'D05.750.716.721.812', 'D25.720.327.811', 'D25.720.716.721.812', 'J01.637.051.720.716.721.812'], ['E05.318.372.500.750.625', 'N05.715.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Secretion of GOB metallo-beta-lactamase in Escherichia coli depends strictly on the cooperation between the cytoplasmic DnaK chaperone system and the Sec machinery: completion of folding and Zn(II) ion acquisition occur in the bacterial periplasm. | Metallo-beta-lactamases (MbetaLs) are zinc-dependent enzymes produced by many clinically relevant gram-negative pathogens that can hydrolyze most beta-lactam antibiotics. MbetaLs are synthesized in the bacterial cytoplasm as precursors and are secreted into the periplasm. Here, we report that the biogenesis process of ... | ['Bacterial Proteins', 'Cefotaxime', 'Cytoplasm', 'Escherichia coli', 'Escherichia coli Proteins', 'Flavobacteriaceae', 'HSP70 Heat-Shock Proteins', 'Models, Biological', 'beta-Lactamases'] | 19,433,552 | [['D12.776.097'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['A11.284.430.214'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['B03.440.080.190', 'B03.440.400.425.310'], ['D12.776.580.216.375'], ['E05.599.395'], ['D08.811.277.087.180']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lead and cadmium contamination and exposure risk assessment via consumption of vegetables grown in agricultural soils of five-selected regions of Pakistan. | Rapid urbanization and industrialization result in serious contamination of soil with toxic metals such as lead (Pb) and cadmium (Cd), which can lead to deleterious health impacts in the exposed population. This study aimed to investigate Pb and Cd contamination in agricultural soils and vegetables in five different ag... | ['Adult', 'Cadmium', 'Child', 'China', 'Consumer Product Safety', 'Female', 'Food Contamination', 'Fruit', 'Humans', 'Lead', 'Male', 'Pakistan', 'Risk Assessment', 'Soil', 'Soil Pollutants', 'Vegetables'] | 27,939,659 | [['M01.060.116'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['M01.060.406'], ['Z01.252.474.164'], ['N06.850.210'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Systematic structure modifications of imidazo[1,2-a]pyrimidine to reduce metabolism mediated by aldehyde oxidase (AO). | N-{trans-3-[(5-Cyano-6-methylpyridin-2-yl)oxy]-2,2,4,4-tetramethylcyclobutyl}imidazo[1,2-a]pyrimidine-3-carboxamide (1) was recently identified as a full antagonist of the androgen receptor, demonstrating excellent in vivo tumor growth inhibition in castration-resistant prostate cancer (CRPC). However, the imidazo[1,2-... | ['Aldehyde Oxidase', 'Bridged Bicyclo Compounds, Heterocyclic', 'Catalytic Domain', 'Cyclobutanes', 'Humans', 'Imidazoles', 'Models, Molecular', 'Oxidation-Reduction', 'Protein Binding', 'Pyrimidines', 'Stereoisomerism', 'Structure-Activity Relationship'] | 21,955,208 | [['D08.811.682.657.163.311'], ['D03.605.084'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D02.455.426.392.368.201'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['E05.599.595'], ['G02.700', 'G03.295.531'], ['G02.111.679', 'G03.808'], ['D03.383.742'], ['G02.607.445.682'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improving rheumatoid arthritis comparative effectiveness research through causal inference principles: systematic review using a target trial emulation framework. | OBJECTIVES: Target trial emulation is an intuitive design framework that encourages investigators to formulate their comparative effectiveness research (CER) question as a hypothetical randomised controlled trial (RCT). Our aim was to systematically review CER studies in rheumatoid arthritis (RA) to provide examples of... | ['Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Comparative Effectiveness Research', 'Humans', 'Observational Studies as Topic', 'Research Design'] | 32,381,560 | [['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['H01.770.644.145.360.500', 'N05.425.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.250.500', 'N05.715.360.330.250.500', 'N06.850.520.450.250.500'], ['E05.581.500', 'H01.770.644.728']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Modeling transcription factor binding sites with Gibbs Sampling and Minimum Description Length encoding. | Transcription factors, proteins required for the regulation of gene expression, recognize and bind short stretches of DNA on the order of 4 to 10 bases in length. In general, each factor recognizes a family of "similar" sequences rather than a single unique sequence. Ultimately, the transcriptional state of a gene is d... | ['Algorithms', 'Base Sequence', 'Binding Sites', 'DNA', 'Databases, Factual', 'Markov Chains', 'Models, Biological', 'Sequence Alignment', 'Stochastic Processes', 'Transcription Factors'] | 9,322,048 | [['G17.035', 'L01.224.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D13.444.308'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Evolutionary Computing Enriched Computer-Aided Diagnosis System for Diabetic Retinopathy: A Survey. | Complications caused due to diabetes mellitus result in significant microvasculature that eventually causes diabetic retinopathy (DR) that keeps on increasing with time, and eventually causes complete vision loss. Identifying subtle variations in morphological changes in retinal blood vessels, optic disk, exudates, mic... | ['Algorithms', 'Diabetic Retinopathy', 'Diagnosis, Computer-Assisted', 'Humans', 'Image Interpretation, Computer-Assisted', 'Retinal Vessels', 'Surveys and Questionnaires'] | 28,534,786 | [['G17.035', 'L01.224.050'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A07.015.611'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Farnesyltransferase regulates neutrophil recruitment and tissue damage in acute pancreatitis. | OBJECTIVES: The signaling mechanisms controlling organ damage in the pancreas in severe acute pancreatitis (AP) remain elusive. Herein, we examined the role of farnesyltransferase signaling in AP.METHODS: Pancreatitis was provoked by the infusion of taurocholate into the pancreatic duct in C57BL/6 mice. Animals were tr... | ['Acinar Cells', 'Acute Disease', 'Amylases', 'Animals', 'Arginine', 'Cells, Cultured', 'Chemokine CXCL2', 'Enzyme Inhibitors', 'Farnesyltranstransferase', 'Lung', 'Macrophage-1 Antigen', 'Male', 'Methionine', 'Mice', 'Mice, Inbred C57BL', 'Neutrophil Infiltration', 'Pancreas', 'Pancreatitis', 'Peroxidase', 'Signal Tra... | 24,622,074 | [['A11.031'], ['C23.550.291.125'], ['D08.811.277.450.066'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.251'], ['D12.644.276.374.200.120.100', 'D12.644.276.374.200.600.940', 'D12.776.467.374.200.120.100', 'D12.776.467.374.200.600.940', 'D23.125.300.120.100', 'D23.125.300.600.940', 'D23... | ['Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Progressive multiple sclerosis: abnormal immune functions in vitro and aberrant correlation with enumeration of lymphocyte subpopulations. | In a series of 27 consecutive progressive multiple sclerosis (MS) patients under age 50 we have simultaneously measured 3 in vitro immune functions and 6 markers and compared their results to a group of 21 controls. We have confirmed a reduction of concanavalin A (Con A) -induced suppression and NK function contrasting... | ['Adult', 'Antibodies, Monoclonal', 'Antigens, Differentiation, T-Lymphocyte', 'Antigens, Surface', 'Female', 'Humans', 'Immunity, Cellular', 'Immunoglobulin G', 'In Vitro Techniques', 'Killer Cells, Natural', 'Lymphocytes', 'Male', 'Multiple Sclerosis', 'T-Lymphocytes, Regulatory'] | 2,940,262 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D23.050.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Study of patient-reported morbidity following V-beam pulsed-dye laser treatment of port wine stains. | The V-beam pulsed-dye laser (PDL) (595 nm) has gained popularity in the treatment of port wine stains (PWS). It uses longer pulse durations than the standard flashlamp-pumped pulsed-dye laser (FPDL) (585 nm) and has an in-built cooling system to protect the epidermis. This should, theoretically, reduce the treatment-as... | ['Adolescent', 'Adult', 'Aged', 'Anesthetics, Local', 'Child', 'Female', 'Humans', 'Low-Level Light Therapy', 'Male', 'Middle Aged', 'Pain', 'Port-Wine Stain', 'Quality of Life', 'Skin Diseases', 'Social Behavior', 'Surveys and Questionnaires', 'Time Factors'] | 16,047,083 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594.540', 'E02.774.500'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Association of genetic dependences between lung cancer and chronic obstructive pulmonary disease. | INTRODUCTION: Recent studies have shown an increased risk of lung cancer in patients with bronchial obstructive changes, including patients with COPD. It seems that there are common factors of pathogenesis of both diseases associated with oxidative stress. In the present paper the genes linked to the repair of oxidativ... | ['Adenocarcinoma', 'Aged', 'Carcinoma, Non-Small-Cell Lung', 'Carcinoma, Squamous Cell', 'Chromosomal Proteins, Non-Histone', 'Comorbidity', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Incidence', 'Iron', 'Lung Neoplasms', 'Male', 'Matrix Metalloproteinase 12', 'Matrix Metalloproteinase 3', 'Middle Aged',... | 23,744,166 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.660.235', 'D12.776.664.235'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regulation of IFN-ã by IL-13 dictates susceptibility to secondary postinfluenza MRSA pneumonia. | Superinfection in mice at day 7 postinfluenza infection exacerbates bacterial pneumonia at least in part via downstream effects of increased IFN-ã signaling. Here we show that up to 3 days postinfluenza infection, mice have reduced susceptibility to superinfection with methicillin-resistant Staphylococcus aureus (MRSA)... | ['Animals', 'Bacterial Load', 'Coinfection', 'Disease Susceptibility', 'Interferon-gamma', 'Interleukin-13', 'Interleukin-13 Receptor alpha2 Subunit', 'Lung', 'Methicillin-Resistant Staphylococcus aureus', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Orthomyxoviridae Infections', 'Pneumonia, ... | 25,091,976 | [['B01.050'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['C01.218'], ['C23.550.291.687', 'G07.100.250'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ethnic discrimination and psychological distress: a study of Sami and non-Sami populations in Norway. | The prevalence of psychological distress and its association with ethnic discrimination was examined among 13,703 participants (36 to 79 years of age) in a population-based study of health and living conditions in areas with indigenous Sami, Kven (descendants of Finnish immigrants), and Ethnic Norwegian populations (th... | ['Adult', 'Aged', 'Bullying', 'Ethnic Groups', 'Female', 'Finland', 'Humans', 'Male', 'Middle Aged', 'Minority Groups', 'Norway', 'Population Groups', 'Prejudice', 'Stress, Psychological', 'Surveys and Questionnaires'] | 22,334,242 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.126.125.550', 'F01.145.813.213.500', 'I01.880.735.070'], ['M01.686.754', 'N01.224.317'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.853.300'], ['Z01.542.816.374'], ['M01.686', 'N01.224.708'], ['F01.145.813.550', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Retinopathy and hypertension affect serum high-sensitivity C-reactive protein levels in Type 2 diabetic patients. | Several studies suggest that inflammation plays an important role in the pathogenesis of diabetes mellitus, as well as atherosclerosis, and acute-phase reactants have been proposed as monitors for the ongoing process of these diseases. We studied the clinical significance of serum high-sensitivity C-reactive protein (h... | ['Biomarkers', 'Body Mass Index', 'C-Reactive Protein', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Diabetic Retinopathy', 'Female', 'Humans', 'Hypertension', 'Inflammation', 'Japan', 'Male', 'Middle Aged', 'Regression Analysis'] | 15,866,055 | [['D23.101'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['B01.050.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Central venous catheter related infections. Inter-Societies update and recommendations]. | Representatives of the Argentine Society of Infectious Diseases (SADI) and the Argentine Society of Intensive Therapy (SATI) joined together to issue specific recommendations for the diagnosis, treatment, and prevention of intravascular catheter related infections (CRI). The methodology used was the analysis of the lit... | ['Anti-Bacterial Agents', 'Bacteremia', 'Catheter-Related Infections', 'Catheterization, Central Venous', 'Central Venous Catheters', 'Humans', 'Practice Guidelines as Topic'] | 30,694,189 | [['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['C01.195'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E07.132.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Surgical costs in an otorhinolaryngology department]. | OBJECTIVE: To describe the costs of the surgical procedures most frequently performed in an Otorhinolaryngology Department.MATERIALS AND METHOD: A descriptive economic analysis of the 5 most frequent surgical procedures performed during 2006, based on the following variables: human resources, non-structural equipment, ... | ['Ambulatory Care', 'Costs and Cost Analysis', 'Cross-Sectional Studies', 'Health Expenditures', 'Health Services', 'Humans', 'Otolaryngology', 'Otorhinolaryngologic Surgical Procedures', 'Spain'] | 18,928,676 | [['E02.760.106', 'N02.421.585.106'], ['N03.219.151'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N03.219.151.450', 'N05.300.385'], ['N02.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.526'], ['E04.580'], ['Z01.542.846']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Inhibition of Aortic Valve Calcification by Local Delivery of Zoledronic Acid-an Experimental Study. | The aim of this study was to evaluate in an experimental model of aortic valve (AV) stenosis the effectiveness of zoledronate on the inhibition of calcification. Sixteen New Zealand rabbits were placed on vitamin D-enriched diet for 3 weeks. All animals underwent PET/CT at baseline and before euthanasia to assess calci... | ['Angioplasty, Balloon, Coronary', 'Animals', 'Aortic Valve', 'Aortic Valve Stenosis', 'Bone Density Conservation Agents', 'Calcinosis', 'Cardiac Catheters', 'Disease Models, Animal', 'Drug Delivery Systems', 'Echocardiography', 'Male', 'Positron Emission Tomography Computed Tomography', 'Rabbits', 'Time Factors', 'Zol... | 29,582,395 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['B01.050'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['D27.505.696.242'], ['C18.452.174.130'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lactic acid inhibition of gap junctional intercellular communication in in vitro astrocytes as measured by fluorescence recovery after laser photobleaching. | Lactic acid can permeate plasma membranes, causing intracellular acidosis. Gap junctions are sensitive to pHi and can be reversibly uncoupled by weak acids. In this study, dye coupling between in vitro astrocytes, presumably mediated by gap junctions, was measured in the absence and presence of lactic acid. Fluorescenc... | ['Animals', 'Astrocytes', 'Cell Communication', 'Cells, Cultured', 'Fluorescent Dyes', 'Intercellular Junctions', 'Lactates', 'Lactic Acid', 'Lasers', 'Microscopy, Fluorescence', 'Time Factors'] | 2,976,397 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['G04.085'], ['A11.251'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A11.284.149.165.420'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['E07.632.490', 'E07.710.520'], ['E01.370.350.515.458', 'E05.595.458'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dumping syndrome after combined pyloroplasty and fundoplication. | Dumping syndrome in infancy is a rare complication following gastric surgery. We describe an 11-month-old infant affected by recurrent peptic oesophagitis who underwent a combined Nissen fundoplication and pyloroplasty. Early dumping symptoms such as irritability, pallor, sweating, abdominal distension and watery diarr... | ['Dumping Syndrome', 'Duodenogastric Reflux', 'Esophagus', 'Gastric Emptying', 'Gastric Fundus', 'Gastroesophageal Reflux', 'Glucose Tolerance Test', 'Humans', 'Infant', 'Male', 'Pylorus', 'Radionuclide Imaging', 'Technetium Tc 99m Sulfur Colloid'] | 2,040,349 | [['C06.405.748.630.310', 'C23.550.767.812.500'], ['C06.405.469.275.700', 'C06.405.748.240'], ['A03.556.875.500'], ['G10.261.360.400'], ['A03.556.875.875.419'], ['C06.405.117.119.500.484'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.7... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical career ladders: Hamot Medical Center. | The clinical career ladder program for pharmacists at Hamot Medical Center (HMC), a 500-bed not-for-profit community teaching hospital, is described. Between 1980 and 1989 a career ladder at HMC evolved from an idea to an established program with parallel administrative, business, and clinical tracks. The development o... | ['Career Mobility', 'Hospital Bed Capacity, 500 and over', 'Hospitals, Community', 'Pennsylvania', 'Pharmacists', 'Pharmacy Administration', 'Pharmacy Service, Hospital', 'Workforce'] | 2,589,340 | [['N01.824.245.175', 'N01.824.547.330'], ['N02.278.306.472.300'], ['N02.278.421.306'], ['Z01.107.567.875.075.550', 'Z01.107.567.875.350.550', 'Z01.107.567.875.500.550'], ['M01.526.485.780', 'N02.360.780'], ['N04.452.706'], ['N02.278.216.500.968.603', 'N02.421.668.556', 'N04.452.442.452.422.603'], ['N04.452.525']] | ['Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Factors influencing activation of B-cells in immunity. | The hypotheses so far advanced for B-cell activation by antigen are based on the assumption that the interaction between antigen and the Ig receptors delivers at least the initial triggering signal. There are few, if any, experimental findings to support this assumption. On the contrary, a variety of findings indicate ... | ['Animals', 'Antibody Formation', 'Antibody-Producing Cells', 'Antigens', 'B-Lymphocytes', 'Binding Sites, Antibody', 'Cell-Free System', 'Cells, Cultured', 'Concanavalin A', 'Dinitrophenols', 'Epitopes', 'Erythrocytes', 'Fibroblasts', 'Hemocyanins', 'Macrophages', 'Mitogens', 'Poly A-U', 'Receptors, Antigen, B-Cell', ... | 48,356 | [['B01.050'], ['G12.450.050.370.250'], ['A11.063', 'A15.382.032'], ['D23.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['A11.284.835.168'], ['A11.251'], ['D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship between Apgar score and umbilical arterial blood gas values in newborns. | The data for this report were derived from 61 newborns and their mothers. Of the newborns 45.9 percent had one-minute Apgar scores of less than seven, and 54.1 percent had Apgar scores of seven or greater. The five-minute Apgar score was less than 7 in 6.6 percent of cases. While 23 percent of newborns had pH values of... | ['Acid-Base Equilibrium', 'Acidosis', 'Apgar Score', 'Carbon Dioxide', 'Female', 'Fetal Blood', 'Hematocrit', 'Hemoglobins', 'Humans', 'Infant, Newborn', 'Oxygen', 'Sensitivity and Specificity'] | 8,993,174 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['C18.452.076.176'], ['E01.370.600.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.776.124.400', 'D12.776.422.316.76... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Site-directed mutagenesis and structural studies suggest that the germination protease, GPR, in spores of Bacillus species is an atypical aspartic acid protease. | Germination protease (GPR) initiates the degradation of small, acid-soluble spore proteins (SASP) during germination of spores of Bacillus and Clostridium species. The GPR amino acid sequence is not homologous to members of the major protease families, and previous work has not identified residues involved in GPR catal... | ['Amino Acid Sequence', 'Aspartic Acid', 'Bacillus megaterium', 'Endopeptidases', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Protein Structure, Tertiary', 'Spores, Bacterial'] | 16,199,582 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['D08.811.277.656.300'], ['L01.453.245.667'], ['E05.393.420.601.575... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pump activated by a foot switch pedal for controlled administration of local anaesthetic drugs. | We describe a newly designed syringe pump which is electrically controlled by a dual foot switch pedal. The device enables the scrubbed anaesthetist performing the regional block to aspirate, as well as to inject, the local anaesthetic without the need for any additional personnel. | ['Anesthetics, Local', 'Drug Administration Schedule', 'Electronics, Medical', 'Equipment Design', 'Foot', 'Humans', 'Infusion Pumps', 'Nerve Block', 'Suction', 'Syringes'] | 11,939,996 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E02.319.283'], ['H01.671.293.319'], ['E05.320'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.505', 'E07.858.082.505'], ['E03.155.086.711', 'E04.525.210.550'], ['E04.237.890'], ['E07.877']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rituximab for the treatment of Churg-Strauss syndrome with renal involvement. | INTRODUCTION: Churg-Strauss syndrome (CSS) is a small vessel systemic vasculitis associated with asthma and eosinophilia that causes glomerulonephritis (GN) in ?25% of patients. Rituximab (RTX) is a chimeric anti-CD20 monoclonal antibody that depletes B cells and is effective in numerous autoimmune diseases including a... | ['Antibodies, Monoclonal, Murine-Derived', 'Churg-Strauss Syndrome', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Immunologic Factors', 'Kidney Diseases', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Pilot Projects', 'Remission Induction', 'Rituximab', 'Survival Rate', '... | 21,325,353 | [['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['C14.907.940.897.249.249', 'C15.604.515.292.015', 'C20.111.193.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Aberrant cerebral network topology and mild cognitive impairment in early Parkinson's disease. | The aim of this study was to assess whether mild cognitive impairment (MCI) is associated with disruption in large-scale structural networks in newly diagnosed, drug-na?ve patients with Parkinson's disease (PD). Graph theoretical analyses were applied to 3T MRI data from 123 PD patients and 56 controls from the Parkins... | ['Brain', 'Brain Mapping', 'Cognitive Dysfunction', 'Disease Progression', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Parkinson Disease'] | 25,950,288 | [['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F03.615.250.700'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['F04.711.513'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hyperinsulinemia and insulin resistance related metabolic syndrome. | BACKGROUND: A cross-sectional study in northern Taiwan was conducted to investigate the role of serum insulin level on the development of hyperglycemia, hypertension, obesity and hyperlipidemia.METHODS: Demographic data (age, gender), body mass index, blood pressure, and laboratory blood tests (uric acid, total cholest... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Humans', 'Hyperglycemia', 'Hyperinsulinism', 'Hyperlipidemias', 'Hypertension', 'Insulin Resistance', 'Male', 'Middle Aged', 'Obesity', 'Uric Acid'] | 11,299,972 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['C18.452.394.968'], ['C18.452.584.500.500'], ['C14.907.489'], ['C18.452.394.968.500', 'G0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relative inhibition of insect phenoloxidase by cyclic fungal metabolites from insect and plant pathogens. | The fungal metabolite kojic acid, which is produced by Aspergillus and Penicillium species fungi that may be pathogens of both insects and plants, was a significant inhibitor of phenoloxidase of different representative beetle and caterpillar insect species. Fusaric acid and picolinic acid, produced by Fusarium spp., w... | ['Animals', 'Aspergillus', 'Chitin', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Fusaric Acid', 'Fusarium', 'Hemolymph', 'Insect Proteins', 'Insecta', 'Monophenol Monooxygenase', 'Penicillium', 'Picolinic Acids', 'Pyrones', 'Spodoptera'] | 11,122,526 | [['B01.050'], ['B01.300.381.081'], ['D05.750.078.139', 'D09.698.211'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['D03.066.707.200', 'D03.383.725.705.200'], ['B01.300.381.366'], ['A13.453'], ['D12.776.093.500'], ['B01.050.500.131.617'], ['D08.811.682.690.708.125.500'], ['B01.300.381.662'], ['D03.066.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonbridging external fixation in the treatment of unstable fractures of the distal forearm. | INTRODUCTION: Unstable fractures of the distal forearm often require surgical treatment to restore the normal anatomy and function. We have used a relatively new technique, nonbridging external fixation, in the treatment of these fractures in our hospital during the past few years. Our results are presented here.MATERI... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', "Colles' Fracture", 'Female', 'Fracture Fixation', 'Fractures, Malunited', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Radius Fractures', 'Range of Motion, Articular', 'Wrist Joint'] | 12,955,539 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.518.336.500', 'C26.289.336.500', 'C26.404.562.356'], ['E04.555.300'], ['C26.404.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['C26.088.268.556', 'C26.404.562'], ['E01.370.600.7... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A general vector, pASK84, for cloning, bacterial production, and single-step purification of antibody Fab fragments. | The expression vector pASK84 was designed for the convenient cloning of immunoglobulin variable domain genes, as well as periplasmic secretion of the corresponding F(ab) fragment in Escherichia coli. The plasmid provides the constant domain genes of mouse IgG1/kappa with a hexa-histidine tag fused to the C terminus of ... | ['Amino Acid Sequence', 'Base Sequence', 'Chromatography, Affinity', 'Cloning, Molecular', 'Escherichia coli', 'Genes, Immunoglobulin', 'Genetic Vectors', 'Immunoglobulin Fab Fragments', 'Molecular Sequence Data', 'Recombinant Fusion Proteins'] | 8,163,179 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.170'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.335', 'G12.500.299'], ['G05.360.337'], ['D12.644.541.500.650', 'D12.776.124.486.485.680.650', 'D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Antitumor activity of small double-stranded oligodeoxynucleotides targeting telomerase RNA in malignant melanoma cells. | Human telomerase RNA (hTR) is an intrinsic component of telomerase enzyme. Small interfering RNAs (siRNAs) and single-stranded antisense oligonucleotides have been used previously for silencing of the hTR. The objective of this study was to investigate the effect of partially double-stranded oligodeoxynucleotides (ODNs... | ['Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Female', 'Gene Knockdown Techniques', 'HeLa Cells', 'Humans', 'Lung Neoplasms', 'Melanoma', 'Mice', 'Mice, Inbred C57BL', 'Oligodeoxyribonucleotides', 'RNA', 'Telomerase', 'Transfection'] | 19,441,892 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.393.335.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HIV RNA persists in rectal tissue despite rapid plasma virologic suppression with dolutegravir-based therapy. | OBJECTIVES: Despite plasma virologic suppression with antiretroviral therapy (ART), HIV persists in gut tissue. The objectives of this study were to compare plasma and rectal tissue HIV RNA dynamics and to assess relationships with dolutegravir (DTG) plasma and tissue concentrations.DESIGN: A longitudinal cohort study ... | ['Adult', 'Anti-HIV Agents', 'Chromatography, Liquid', 'Female', 'HIV Infections', 'HIV-1', 'Heterocyclic Compounds, 3-Ring', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Oxazines', 'Piperazines', 'Plasma', 'Prospective Studies', 'Pyridones', 'RNA, Viral', 'Rectum', 'Tandem Mass Spectrometry', 'Viral Load'... | 30,005,011 | [['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E05.196.181.400'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['D03.633.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nonisotopic single strand conformation analysis of the 5 alpha-reductase type 2 gene for the diagnosis of 5 alpha-reductase deficiency. | 5 alpha-Reductase deficiency is a rare autosomal recessive disorder of defective virilization in karyotypic males due to reduced conversion of testosterone to dihydrotestosterone. The gene encoding the affected 5 alpha-reductase type 2 enzyme has recently been cloned, and mutations within the coding region have been di... | ['3-Oxo-5-alpha-Steroid 4-Dehydrogenase', 'Amino Acid Sequence', 'Base Sequence', 'Consanguinity', 'DNA', 'Humans', 'Isoenzymes', 'Leukocytes', 'Male', 'Molecular Sequence Data', 'Point Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Single-Stranded Conformational'] | 8,784,107 | [['D08.811.682.660.465'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.090.403.180', 'G05.180'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['L01.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of an orthotopic human pancreatic cancer xenograft model using ultrasound guided injection of cells. | Mice have been employed as models of cancer for over a century, providing significant advances in our understanding of this multifaceted family of diseases. In particular, orthotopic tumor xenograft mouse models are emerging as the preference for cancer research due to increased clinical relevance over subcutaneous mou... | ['Animals', 'Cell Transformation, Neoplastic', 'Disease Models, Animal', 'Female', 'HCT116 Cells', 'Humans', 'Immunocompromised Host', 'Injections', 'Mice', 'Molecular Imaging', 'Pancreas', 'Pancreatic Neoplasms', 'Peritoneal Neoplasms', 'Reproducibility of Results', 'Spectrometry, Fluorescence', 'Surgery, Computer-Ass... | 21,647,423 | [['B01.050'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['E02.319.267.530'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.557', 'E05.601.555'], ['A... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Photosynthetic action spectra of the energy storage in bundle sheath cells of Zea mays. | Photosynthetic action spectra (Formula: see text), (Carpentier, R., Larue, B. and Leblanc, R. (1984) Arch. Biochem. Biophys. 228, 534-543.), from 400 to 750 nm were studied in bundle sheath cells of maize. Photosynthetic action spectra in the presence of 10 mM ascorbate or 4 mM ribose-5-phosphate were increased and shi... | ['Chloroplasts', 'Energy Metabolism', 'Photosynthesis', 'Plants', 'Spectrophotometry', 'Zea mays'] | 3,579,902 | [['A11.284.430.214.190.875.700.140'], ['G03.295'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['B01.650'], ['E05.196.712.726', 'E05.196.867.826'], ['B01.650.940.800.575.912.250.822.966']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retention of tocilizumab with and without methotrexate during maintenance therapy for rheumatoid arthritis: the ACTRA-RI cohort study. | OBJECTIVES: To compare retention of tocilizumab (TCZ) as monotherapy vs combination therapy with MTX in RA patients achieving clinical improvements during the first year.METHODS: We performed a multicentre cohort study using a real-life registry containing RA patients who had begun TCZ with or without MTX between April... | ['Aged', 'Antibodies, Monoclonal, Humanized', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Cohort Studies', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Humans', 'Maintenance Chemotherapy', 'Male', 'Methotrexate', 'Middle Aged', 'Registries', 'Remission Induction', '... | 30,793,749 | [['M01.060.116.100'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.319.283'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Screening of genetic parameters for soluble protein expression in Escherichia coli. | Soluble expression of proteins in a relevant form for functional and structural investigations still often remains a challenge. Although many biochemical factors are known to affect solubility, a thorough investigation of yield-limiting factors is normally not feasible in high-throughput efforts. Here we present a scre... | ['Cloning, Molecular', 'Codon', 'Disulfides', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Escherichia coli Proteins', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Interleukins', 'Plasmids', 'Protein Engineering', 'Recombinant Fusion Proteins', 'Reproducibility of Results', 'Solubility', '... | 21,130,169 | [['E05.393.220'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['B01.050.150.900.649.313.988.400.112.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Apparent affinity of the Na/K pump for ouabain in cultured chick cardiac myocytes. Effects of Nai and Ko. | The measured apparent affinity (K0.5) of the Na/K pump for ouabain has been reported to vary over a wide range. In a previous report we found that changing Nai could alter apparent affinity by at least an order of magnitude and that the model presented predicted this variability. To increase our understanding of this v... | ['Animals', 'Barium', 'Binding Sites', 'Cells, Cultured', 'Chick Embryo', 'Electric Conductivity', 'Membrane Potentials', 'Microelectrodes', 'Models, Biological', 'Monensin', 'Myocardium', 'Ouabain', 'Protein Conformation', 'Sodium', 'Sodium-Potassium-Exchanging ATPase'] | 1,660,063 | [['B01.050'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['G02.111.570.120'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['G01.358.500.249.277'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E07.305.250.500'], ['E05.599.395'], ['D03.383.312.600'], ['A02.633.580', 'A07... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bully victimization and child and adolescent health: new evidence from the 2016 NSCH. | PURPOSE: To explore whether children with diagnosable health conditions are at greater risk of bully victimization and whether, among these children, bully victimization further elevates the risk of an array of health difficulties.METHODS: We examined a recent, nationally representative sample of children and adolescen... | ['Adolescent', 'Aggression', 'Bullying', 'Child', 'Chronic Disease', 'Crime Victims', 'Cross-Sectional Studies', 'Developmental Disabilities', 'Disabled Children', 'Female', 'Health Surveys', 'Humans', 'Male', 'Peer Group', 'Prevalence', 'Risk Factors', 'Schools', 'Students', 'Surveys and Questionnaires', 'United State... | 30,287,165 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.145.126.125.550', 'F01.145.813.213.500', 'I01.880.735.070'], ['M01.060.406'], ['C23.550.291.500'], ['M01.135'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.625.421'], ['M01.150.200'], ['E05.318.308.980.438', 'N05.71... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Orthoses in patients with poliomyelitis]. | Poliomyelitis, in spite of vaccination, is still a problem: in the third world as well as for the victims of the epidemics of the first half of this century, who now, becoming older, have growing difficulties to overcome their paralyses. They needed and still need orthoses for walking. How do they manage? And what can ... | ['Adolescent', 'Adult', 'Aged', 'Braces', 'Child', 'Female', 'Gait', 'Humans', 'Locomotion', 'Male', 'Middle Aged', 'Poliomyelitis'] | 7,631,282 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.858.442.743.319'], ['M01.060.406'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568.500', 'G11.427.410.568'], ['M01.060.116.630'], ['C01.207.618.750', 'C01.925.782.687.359.764', 'C10.228.228.618.750'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of the suppressor cell(s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells. | Anterior chamber-associated immune deviation (ACAID) is a complex set of immune responses induced by the inoculation of antigens into the anterior chamber of the eye. Histocompatibility antigens, tumor-specific antigens, reactive haptens, and viral antigens have been shown to induce this phenomenon, which comprises the... | ['Animals', 'Anterior Chamber', 'Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Female', 'Histocompatibility Antigens Class II', 'Hypersensitivity, Delayed', 'Immunization, Passive', 'Lymphocyte Transfusion', 'Mast-Cell Sarcoma', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred DBA', 'Models, Biological', 'Neoplasm Transp... | 3,155,766 | [['B01.050'], ['A09.371.060.067'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['C20.543.418'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['E02.095.135.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microwave assisted solvent extraction and coupled-column reversed-phase liquid chromatography with UV detection use of an analytical restricted-access-medium column for the efficient multi-residue analysis of acidic pesticides in soils. | A screening method has been developed for the determination of acidic pesticides in various types of soils. Methodology is based on the use of microwave assisted solvent extraction (MASE) for fast and efficient extraction of the analytes from the soils and coupled-column reversed-phase liquid chromatography (LC-LC) wit... | ['Chromatography, Liquid', 'Hydrogen-Ion Concentration', 'Microwaves', 'Pesticide Residues', 'Soil Pollutants', 'Solvents', 'Spectrophotometry, Ultraviolet'] | 11,771,842 | [['E05.196.181.400'], ['G02.300'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['D27.888.284.756'], ['D27.720.844'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Do learning handicaps and headache cluster? | Children who are brought to medical attention because of frequently recurring or disabling headaches appear to have an increased prevalence of learning handicaps. Some of this increase might reflect Berkson's principle--the selection bias of an overrepresentation of patients with two disorders. Consideration is given t... | ['Child', 'Headache', 'Humans', 'Learning Disabilities', 'Models, Neurological', 'Models, Psychological', 'Probability'] | 3,598,136 | [['M01.060.406'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['E05.599.395.642'], ['E05.599.695'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Femoropopliteal and femorotibial arterial reconstructive surgery. Special reference to the autogenous venous bypass procedure using unreversed vein after eversion valvectomy. | The outcome of 127 femoropopliteal and 23 femorotibial arterial reconstructions carried out between January 1960 and December 1972 has been reviewed. The operative method was autogenous saphenous vein bypass in 109 cases, 82 of which were performed using unreversed vein with eversion valvectomy. The indication for reco... | ['Adult', 'Aged', 'Amputation', 'Angiography', 'Arteries', 'Blood Vessel Prosthesis', 'Female', 'Femoral Artery', 'Finland', 'Follow-Up Studies', 'Hemorrhage', 'Humans', 'Intermittent Claudication', 'Ischemia', 'Leg', 'Leg Ulcer', 'Male', 'Middle Aged', 'Polyethylene Terephthalates', 'Popliteal Artery', 'Postoperative ... | 127,495 | [['M01.060.116'], ['M01.060.116.100'], ['E04.555.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A07.015.114'], ['E07.695.110'], ['A07.015.114.351'], ['Z01.542.816.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
The network of antigen-antibody reactions in adult women with breast cancer or benign breast pathology or without breast pathology. | The Immunoglobulin G (IgG) antibody response to different protein antigens of the mammary ductal carcinoma by adult women affected by Breast Cancer (BC) distinguishes at least 103 proteins that differ in their molecular weights (MW). The IgG producing cell clones (nodes) coexist with each other in each individual organ... | ['Adolescent', 'Adult', 'Aged', 'Antigen-Antibody Reactions', 'Antigens, Neoplasm', 'Biomarkers, Tumor', 'Breast', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'Case-Control Studies', 'Female', 'Follow-Up Studies', 'Gene Regulatory Networks', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', '... | 25,781,932 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G12.122'], ['D23.050.285'], ['D23.101.140'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.180.43... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rheumatoid factor in the serum of hepatitis C virus-infected patients: an increase in the titre during cold storage. | Storage of serum at 4 degrees C elevated the titre of rheumatoid factor (RF) as measured by nephelometry with IgG-coated latex in 12 of 38 specimens positive for hepatitis C virus. Increased RF following cold storage was not detected in HCV-negative sera. Most of the sera showing the cold-dependent elevation of RF had ... | ['Cold Temperature', 'Complement Activation', 'Cryoglobulins', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Nephelometry and Turbidimetry', 'Rheumatoid Factor', 'Specimen Handling'] | 8,888,977 | [['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G12.274'], ['D12.776.124.486.485.900.225', 'D12.776.124.790.651.900.225', 'D12.776.377.715.548.900.225'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Jejunal pouch with nerve preservation and interposition after total gastrectomy. | BACKGROUND/AIMS: In this paper, we describe operative technique details and our results with a modified technique for jejunal pouch formation and interposition after total gastrectomy, with an overall aim to achieve results superior to jejunal pouch and Roux-en-Y reconstruction, as reported in the literature.METHODOLOG... | ['Female', 'Gastrectomy', 'Humans', 'Jejunum', 'Male', 'Middle Aged', 'Postoperative Complications', 'Quality of Life', 'Stomach Neoplasms', 'Surgical Stapling', 'Surgically-Created Structures', 'Treatment Outcome'] | 9,638,451 | [['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.500', 'A03.556.249.750'], ['M01.060.116.630'], ['C23.550.767'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789'], ['E04.987.775.800'], ['A10.850... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The effect of load on biomechanics during an overhead lift in the WorkHab Functional Capacity Evaluation. | OBJECTIVE: The role of biomechanics during the overhead lift has not been widely investigated. This study aimed to evaluate any change in biomechanics between safe minimum and safe maximum overhead lifts during the WorkHab Functional Capacity Evaluation.METHOD: Thirty healthy participants (age range 18-22 years) were v... | ['Adolescent', 'Biomechanical Phenomena', 'Disability Evaluation', 'Elbow Joint', 'Female', 'Humans', 'Lifting', 'Male', 'Reproducibility of Results', 'Shoulder Joint', 'Spine', 'Video Recording', 'Weight-Bearing', 'Work Capacity Evaluation', 'Young Adult'] | 22,927,589 | [['M01.060.057'], ['G01.154.090', 'G01.374.089'], ['E01.370.400'], ['A02.835.583.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.669'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A02.835.583.748'], ['A02.835.232.834'], ['L01.280.960'], ['G01.374.965'], ['E01.37... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Transcriptomic analysis of Shiga-toxigenic bacteriophage carriage reveals a profound regulatory effect on acid resistance in Escherichia coli. | Shiga-toxigenic bacteriophages are converting lambdoid phages that impart the ability to produce Shiga toxin to their hosts. Little is known about the function of most of the genes carried by these phages or the impact that lysogeny has on the Escherichia coli host. Here we use next-generation sequencing to compare the... | ['Bacteriophages', 'Escherichia coli O157', 'Gene Expression Profiling', 'Prophages', 'Sequence Analysis, RNA', 'Transcriptome', 'Viral Proteins'] | 26,386,055 | [['B04.123'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150.180.100.800.250.500'], ['E05.393.332'], ['B04.123.655'], ['E05.393.760.710'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920'], ['D12.776.964']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Svelte integrated delivery system performance examined through diagnostic catheter delivery: the SPEED registry. | AIMS: The multi-center SPEED registry evaluated the procedural success and in-hospital clinical outcomes of direct stenting with the Svelte 'all-in-one' coronary stent Integrated Delivery System (IDS) through diagnostic catheters to identify the clinical indications for which this approach is appropriately suited.METHO... | ['Aged', 'Cardiac Catheterization', 'Cardiac Catheters', 'Clinical Competence', 'Coronary Artery Disease', 'Cost Savings', 'Cost-Benefit Analysis', 'Equipment Design', 'Europe', 'Feasibility Studies', 'Female', 'Femoral Artery', 'Health Care Costs', 'Humans', 'Learning Curve', 'Male', 'Middle Aged', 'Percutaneous Coron... | 25,130,948 | [['M01.060.116.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E07.132.750.249'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['N03.219.151.160.200'], ['N03.219.151.125'], ['E05.320'], ['Z01.542'], ['E05.318.372.550', 'E05.337... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Risk for developmental coordination disorder correlates with gestational age at birth. | BACKGROUND: Studies suggest that children born very preterm have a high risk of developmental coordination disorder (DCD). We examined the relation between the larger spectrum of gestational age at birth and the risk of DCD.METHODS: We used the 7-year follow-up data from 22898 singletons in the Danish National Birth ... | ['Adolescent', 'Child', 'Child, Preschool', 'Confidence Intervals', 'Denmark', 'Follow-Up Studies', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Infant, Postmature', 'Infant, Premature', 'Longitudinal Studies', 'Motor Skills Disorders', 'Risk Factors', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 23,061,693 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['Z01.542.816.124'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pain and quality of life (QoL) in elderly: the Turkish experience. | PURPOSE: The aims of this study were to evaluate the effects of demographic and clinical determinants on pain and to investigate the possible risk factors that disrupt QoL.MATERIALS AND METHODS: The design of this research was a prospective study performed in tertiary care hospital-based physical medicine and rehabilit... | ['Aged', 'Aged, 80 and over', 'Comorbidity', 'Depression', 'Female', 'Geriatric Assessment', 'Humans', 'Incidence', 'Male', 'Pain', 'Pain Measurement', 'Prevalence', 'Prospective Studies', 'Quality of Life', 'Risk Factors', 'Social Class', 'Surveys and Questionnaires', 'Tertiary Healthcare', 'Turkey'] | 22,104,759 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N0... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Congenital myopathies are mainly associated with a mild cardiac phenotype. | BACKGROUND: To evaluate the prevalence of cardiac involvement in patients with congenital myopathies and the association to specific genotypes.METHODS: We evaluated patients with physical examination, electrocardiogram, echocardiography, and 48-h Holter monitoring. Follow-up was performed for major events.RESULTS: We i... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Echocardiography', 'Electrocardiography, Ambulatory', 'Female', 'Follow-Up Studies', 'Heart Diseases', 'Humans', 'Male', 'Middle Aged', 'Muscular Diseases', 'Phenotype', 'Young Adult'] | 30,874,888 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular cloning of cDNA coding for rat plasma glutathione peroxidase. | The plasma glutathione peroxidase (PGSH-PO), which is different from erythrocyte glutathione peroxidase (EGSH-PO) in immunochemical property and substrate specificity, was purified from male Wistar rat serum. The amino acid sequence of 5 independent peptides were determined and a cDNA clone for this enzyme was isolated... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'Codon', 'DNA', 'Glutathione Peroxidase', 'Male', 'Molecular Sequence Data', 'Rats', 'Rats, Inbred Strains', 'Sequence Homology, Nucleic Acid'] | 2,101,919 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308'], ['D08.811.682.732.500'], ['L01.453.245.667'], ['B01.050.150.900.649.313.992.635.505.700'], ['B... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An assessment of a system to monitor the activity of patients in a rehabilitation programme. | The need for an objective quantitative method of monitoring performance in the natural environment for use in a rehabilitation programme is discussed. A system of monitoring the number of steps taken has been developed for an amputee programme as a first attempt towards this goal. Instrumentation consists of an inexpen... | ['Activities of Daily Living', 'Amputees', 'Artificial Limbs', 'Female', 'Humans', 'Information Systems', 'Locomotion', 'Male', 'Monitoring, Physiologic'] | 503,802 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Successful treatment of non-small cell lung cancer with gefitinib after severe erlotinib-related hepatotoxicity. | Gefitinib and erlotinib are first-generation small molecular inhibitors of EGFR tyrosine kinase activity. To the best of our knowledge, to date, two reports have stated that patients with NSCLC who develop severe hepatotoxicity secondary to gefitinib treatment can be safely switched to erlotinib. However, the reverse s... | ['Antineoplastic Agents', 'Carcinoma, Non-Small-Cell Lung', 'Chemical and Drug Induced Liver Injury', 'Erlotinib Hydrochloride', 'Female', 'Gefitinib', 'Humans', 'Middle Aged', 'Protein Kinase Inhibitors', 'Quinazolines', 'Treatment Outcome'] | 22,333,382 | [['D27.505.954.248'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['D03.633.100.786.375'], ['D03.633.100.786.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D27.505.519.389.755'], ['D03.633.100.786']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mediterranean diet, kidney function, and mortality in men with CKD. | BACKGROUND AND OBJECTIVES: Adherence to a Mediterranean diet may link to a better preserved kidney function in the community as well as a favorable cardiometabolic profile and reduced mortality risk in individuals with manifest CKD.DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Dietary habits were determined by 7-day d... | ['Aged', 'Case-Control Studies', 'Diet, Mediterranean', 'Glomerular Filtration Rate', 'Humans', 'Kidney', 'Male', 'Patient Compliance', 'Renal Insufficiency, Chronic', 'Survival Rate', 'Sweden'] | 23,744,002 | [['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.642.249.270', 'G07.203.650.240.270'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cost-effectiveness of pediatric epilepsy surgery compared to medical treatment in children with intractable epilepsy. | PURPOSE: Due to differences in epilepsy types and surgery, economic evaluations of epilepsy treatment in adults cannot be extrapolated to children. We evaluated the cost-effectiveness of epilepsy surgery compared to medical treatment in children with intractable epilepsy.METHOD: Decision tree analysis was used to evalu... | ['Adolescent', 'Anticonvulsants', 'Child', 'Child, Preschool', 'Cost-Benefit Analysis', 'Epilepsy', 'Female', 'Follow-Up Studies', 'Health Care Costs', 'Humans', 'Male', 'Neurosurgical Procedures', 'Pediatrics', 'Retrospective Studies', 'Sensitivity and Specificity'] | 21,306,874 | [['M01.060.057'], ['D27.505.954.427.080'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.125'], ['C10.228.140.490'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.525'], ['H02.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Radio-necrosis of the temporal bone presenting as cerebellopontine angle lesion. | We report a case of osteoradionecrosis of the temporal bone which presented with symptoms and signs of cerebellopontine angle lesion. The clinical, radiological, histological and bacteriological findings are reported. The occurrence of osteoradionecrosis of the temporal bone and the factors which predispose to it are d... | ['Bone Diseases', 'Cerebellar Diseases', 'Cerebellopontine Angle', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Osteoradionecrosis', 'Radiation Injuries', 'Temporal Bone', 'Time Factors'] | 2,370,472 | [['C05.116'], ['C10.228.140.252'], ['A08.186.211.132.810.428.200.462'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C26.733.579', 'G01.750.748.500.579'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['A02.835.232.781.885'], ['G01.910.857']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In Vivo Voltage-Sensitive Dye Imaging of Mammalian Cortex Using "Blue" Dyes. | Optical recording of membrane potential allows simultaneous measurements to be taken from many different locations in the nervous system. This is important in studies of the nervous system in which simultaneous activity can occur at the regional, cellular, and subcellular levels. New "blue" dyes, developed by Amiram Gr... | ['Animals', 'Cerebral Cortex', 'Coloring Agents', 'Rats, Long-Evans', 'Rats, Wistar', 'Voltage-Sensitive Dye Imaging'] | 26,527,769 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['D27.720.233'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['E01.370.350.887']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transformation of dissolved organic matters in swine, cow and chicken manures during composting. | The changes of dissolved organic matters (DOMs) extracted from swine, cow and chicken manures were assessed by Fourier transform infrared, ultraviolet, gel permeation chromatography (GPC), excitation-emission-matrix fluorescence (EEM-FL), Biolog Eco and (1)H NMR during 60-day composting. Pumice was adopted to eliminate... | ['Animals', 'Cattle', 'Chickens', 'Chromatography, Gel', 'Manure', 'Nitrogen', 'Organic Chemicals', 'Proton Magnetic Resonance Spectroscopy', 'Soil', 'Solubility', 'Spectrometry, Fluorescence', 'Spectrophotometry, Ultraviolet', 'Spectroscopy, Fourier Transform Infrared', 'Swine', 'Volatilization'] | 24,813,566 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.250'], ['D20.601'], ['D01.268.604', 'D01.362.625'], ['D02'], ['E05.196.867.519.775'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G02.805'], ['E05.196.712.516.600.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cerebral activation related to the control of mastication during changes in food hardness. | To investigate the neural network involved in the control of mastication during changes in food hardness, we employed functional magnetic resonance imaging while 15 healthy subjects chewed gum whose hardness was changed by chewing. By comparing the areas activated when the hardness of the bolus varied widely with those... | ['Adult', 'Brain', 'Brain Mapping', 'Eating', 'Female', 'Food', 'Functional Laterality', 'Hardness', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Mastication', 'Reference Values'] | 17,320,301 | [['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.300', 'J02.500'], ['F02.830.297.425', 'G11.561.225.425'], ['G01.374.647'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G07.203.650.2... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Microscopic skin laceration segmentation and classification: A framework of statistical normal distribution and optimal feature selection. | Among precision medical techniques, medical image processing is rapidly growing as a successful tool for cancer detection. Skin cancer is one of the crucial cancer types. It is identified through computer vision (CV) techniques using dermoscopic images. The early diagnosis skin cancer from dermoscopic images can be dec... | ['Automation, Laboratory', 'Biostatistics', 'Humans', 'Image Processing, Computer-Assisted', 'Lacerations', 'Normal Distribution', 'Optical Imaging', 'Skin', 'Skin Neoplasms'] | 31,168,871 | [['E05.064', 'J01.897.104.416'], ['E05.318.740.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C26.540'], ['E05.318.740.994.500', 'G17.820.500', 'N05.715.360.750.750.565', 'N06.850.520.830.994.500'], ['E01.370.350.589', 'E05.642'], ['A17.815'], ['C04.588.805', 'C17.800.882']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[Capacities of transabdominal ultrasound study in the diagnosis of polyps of the stomach and colon]. | The data obtained from studies of 84 patients with polyps of the stomach and colonic were used to consider the capacities of transabdominal and transrectal ultrasound studies and their diagnostic efficiency in the diagnosis of polyps of the stomach and colon. The ultrasound semiotics of polyps of the gastric and colon ... | ['Adult', 'Aged', 'Colonic Polyps', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polyps', 'Stomach Neoplasms', 'Ultrasonography'] | 12,577,664 | [['M01.060.116'], ['M01.060.116.100'], ['C23.300.825.411.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.300.825'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789'], ['E01.370.350.850']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pyoderma caused by Pseudomonas aeruginosa infection in dogs: 20 cases. | In this report we describe the historical, clinical, histopathological and microbiological features, as well as treatments and clinical outcome, of pyoderma where Pseudomonas aeruginosa alone was isolated on bacterial culture from lesional skin. Twenty dogs were included in this retrospective study. Seven dogs without ... | ['Administration, Cutaneous', 'Administration, Oral', 'Animals', 'Anti-Bacterial Agents', 'Cephalexin', 'Dog Diseases', 'Dogs', 'Female', 'Fluoroquinolones', 'Male', 'Medical Records', 'Ohio', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Pyoderma', 'Retrospective Studies', 'Silver Sulfadiazine'] | 17,083,575 | [['E02.319.267.120.060'], ['E02.319.267.100'], ['B01.050'], ['D27.505.954.122.085'], ['D02.065.589.099.249.200', 'D02.886.665.074.200', 'D03.633.100.300.249.200'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['D03.633.100.810.835.322'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Late recurrent hemarthrosis following knee arthroplasty associated with epithelioid angiosarcoma of bone. | We report a case of recurrent hemarthrosis 1 year following total knee arthroplasty in a patient with no bleeding diathesis, the hemarthrosis was found to be related to, and led to the diagnosis of high grade sarcoma of the proximal tibia. Twenty five years earlier, he sustained a lateral tibial plateau fracture and wa... | ['Aged', 'Amputation', 'Arthroplasty, Replacement, Knee', 'Bone Neoplasms', 'Epithelioid Cells', 'Hemarthrosis', 'Humans', 'Male', 'Osteosarcoma', 'Postoperative Complications', 'Radiotherapy', 'Recurrence'] | 19,945,286 | [['M01.060.116.100'], ['E04.555.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['C04.588.149', 'C05.116.231'], ['A11.329.372.300', 'A11.627.482.300', 'A11.733.397.300', 'A15.382.670.522.300', 'A15.382.680.397.300'], ['C05.550.459', 'C23.550.414.794'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis, structure, and antiproliferative activity of ruthenium(II) arene complexes with N,O-chelating pyrazolone-based â-ketoamine ligands. | Novel ruthenium half-sandwich complexes containing (N,O)-bound pyrazolone-based â-ketoamine ligands have been prepared, and the solid-state structures of one ligand and five complexes have been determined by single-crystal X-ray diffraction. Some of the complexes display moderate cytotoxicity toward the human ovarian c... | ['Amination', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Chelating Agents', 'Coordination Complexes', 'Crystallography, X-Ray', 'Drug Screening Assays, Antitumor', 'Female', 'Humans', 'Models, Molecular', 'Ovarian Neoplasms', 'Pyrazolones', 'Ruthenium'] | 25,412,203 | [['G02.111.053', 'G02.607.110', 'G03.068'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D01.234', 'D02.257'], ['E05.196.309.742.225'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanism and kinetics of low-temperature oxidation of a biodiesel surrogate: methyl propanoate radicals with oxygen molecule. | This paper presents a computational study on the low-temperature mechanism and kinetics of the reaction between molecular oxygen and alkyl radicals of methyl propanoate (MP), which plays an important role in low-temperature oxidation and/or autoignition processes of the title fuel. Their multiple reaction pathways eith... | ['Free Radicals', 'Kinetics', 'Oxidation-Reduction', 'Oxygen', 'Propionates', 'Quantum Theory', 'Temperature'] | 25,822,662 | [['D01.339', 'D02.389'], ['G01.374.661', 'G02.111.490'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['D02.241.081.751', 'D10.251.400.706'], ['H01.671.579.800'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Delta-9-tetrahydrocannabinol decreases masticatory muscle sensitization in female rats through peripheral cannabinoid receptor activation. | BACKGROUND: This study investigated whether intramuscular injection of delta-9-tetrahydrocannabinol (THC), by acting on peripheral cannabinoid (CB) receptors, could decrease nerve growth factor (NGF)-induced sensitization in female rat masseter muscle; a model which mimics the symptoms of myofascial temporomandibular d... | ['Animals', 'Cannabinoid Receptor Agonists', 'Disease Models, Animal', 'Dronabinol', 'Female', 'Masseter Muscle', 'Mechanoreceptors', 'Myofascial Pain Syndromes', 'Nerve Growth Factor', 'Neurons', 'Rats', 'Rats, Sprague-Dawley', 'Receptor, Cannabinoid, CB1', 'Receptor, Cannabinoid, CB2', 'Trigeminal Ganglion'] | 28,722,246 | [['B01.050'], ['D27.505.519.625.085.500', 'D27.505.696.399.472.188.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.455.849.090.810'], ['A02.633.567.600.500', 'A14.530.630'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['C05.651.550'], ['D12.644.276.860.437', 'D12.776.467.860.437', 'D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of CRIB (clinical risk index for babies) score in auditing the performance of one neonatal intensive care unit. | The CRIB (clinical risk index of babies) score was developed to overcome the disadvantages of birthweight-specific comparisons between neonatal units. The aims of this study were to assess the ability of CRIB score compared to birthweight and gestational age to predict hospital mortality in very low birthweight infants... | ['Analysis of Variance', 'Birth Weight', 'Chi-Square Distribution', 'Gestational Age', 'Hospital Mortality', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Infant, Very Low Birth Weight', 'Intensive Care Units, Neonatal', 'Logistic Models', 'Medical Audit', 'Predictive Value of Tests', 'ROC Curve', 'Retrospective St... | 9,512,208 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['G07.345.500.325.235... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Descending perineum syndrome: are abdominal hysterectomy and bowel habits linked? | PURPOSE: This retrospective study evaluates the effect of abdominal hysterectomy on patients affected by descending perineum syndrome.METHODS: Eighty-nine female patients affected by descending perineum syndrome and one group of 10 healthy women with normal bowel habits were studied retrospectively. Thirty-two descendi... | ['Aged', 'Constipation', 'Defecography', 'Fecal Incontinence', 'Female', 'Humans', 'Hysterectomy', 'Intussusception', 'Manometry', 'Middle Aged', 'Pelvic Floor', 'Perineum', 'Rectum', 'Retrospective Studies', 'Syndrome'] | 16,228,840 | [['M01.060.116.100'], ['C23.888.821.150'], ['E01.370.350.700.715.250'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C06.405.469.531.577'], ['E05.559'], ['M01.060.116.630'], ['A01.923.600.600', 'A02.633.567.050.750'], ['A01.719'], ['A03.556.124.526.767', 'A03.556.249.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Successful Example of How to Implement and Develop a Deceased Organ Donation System in the Caribbean Region: Five-Year Experience of the SEUSA Program in Trinidad and Tobago. | BACKGROUND: The SEUSA program, the Donation and Transplantation Institute foundation consultancy program, was implemented in Trinidad and Tobago (T&T) in 2010 with the support of the National Organ Transplant Unit (NOTU) and the Ministry of Health of T&T.METHODS: The SEUSA program included (1) diagnosis of the current ... | ['Humans', 'Organ Transplantation', 'Program Development', 'Surveys and Questionnaires', 'Tissue Donors', 'Tissue and Organ Procurement', 'Trinidad and Tobago'] | 26,518,918 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.936.450'], ['N04.452.760'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['M01.898'], ['N02.421.911'], ['Z01.107.084.900.900', 'Z01.639.880.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clinical pharmacology of non opioid analgesics in neonates. | An integrated approach of neonatal analgesia starts with the systematic evaluation of pain and should be followed by effective interventions, mainly based on the appropriate (i.e. safe and effective) administration of analgesics. In contrast to the more potent opioids, data on the pharmacokinetics and -dynamics of non-... | ['Acetaminophen', 'Analgesia', 'Analgesics, Non-Narcotic', 'Cohort Studies', 'Female', 'Gestational Age', 'Glomerular Filtration Rate', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Metabolic Clearance Rate'] | 16,408,826 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['E03.091'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.345.500.325.235.968', 'G08.686.320'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The care and feeding of your high-profile patients. | Doctors and practices enjoy, for the most part, taking care of a high-profile patient. However, with the gratification and ego boost that come from being "chosen" to care for these individuals, there are potential risks and decision-making principles that must not be compromised. As a physician, a high-profile patient ... | ['Famous Persons', 'Humans', 'Physician-Patient Relations', 'Practice Management, Medical', 'Privacy'] | 23,767,122 | [['K01.517.211.506', 'M01.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.675', 'N05.300.660.625'], ['N04.452.758.708.450'], ['I01.880.604.473.352.500', 'N03.706.437.352.500', 'N03.706.615.862']] | ['Humanities [K]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Preferential inhibition of the platelet-derived growth factor receptor tyrosine kinase by staurosporine. | Ligand stimulation of the platelet-derived growth factor receptor (PDGF-R) results in rapid activation of the receptor tyrosine kinase, stimulation of phosphoinositide hydrolysis, an increase in intracellular free Ca2+ concentration ([Ca2+]i), and, ultimately, cellular proliferation. In a previous study, we demonstrate... | ['Alkaloids', 'Animals', 'Calcium', 'Cell Line', 'Fibroblasts', 'Humans', 'Inositol', 'Inositol Phosphates', 'Kinetics', 'Mice', 'Phosphatidylinositols', 'Phosphorylation', 'Platelet-Derived Growth Factor', 'Protein Kinase Inhibitors', 'Receptors, Cell Surface', 'Receptors, Platelet-Derived Growth Factor', 'Staurospori... | 2,173,705 | [['D03.132'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.519', 'D09.853.519'], ['D02.033.800.519.400', 'D09.853.519.400', 'D09.894.480'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.99... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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