Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants. | We found that the simple addition of L-methionine to the wild type of Corynebacterium glutamicum results in excretion of the cellular building block L-lysine up to rates of 2.5 nmol/min/mg (dry weight). Biochemical analyses revealed that L-methionine represses the homoserine dehydrogenase activity and reduces the intra... | ['Biological Transport', 'Corynebacterium', 'Glutamic Acid', 'Homoserine Dehydrogenase', 'Isoleucine', 'Lysine', 'Methionine', 'Mutation'] | 7,608,075 | [['G03.143'], ['B03.510.024.250', 'B03.510.460.400.400.200'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D08.811.682.047.820.300'], ['D12.125.070.577', 'D12.125.142.383'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative high-density microarray analysis of gene expression during growth of Lactobacillus helveticus in milk versus rich culture medium. | Lactobacillus helveticus CNRZ32 is used by the dairy industry to modulate cheese flavor. The compilation of a draft genome sequence for this strain allowed us to identify and completely sequence 168 genes potentially important for the growth of this organism in milk or for cheese flavor development. The primary aim of ... | ['Adaptation, Physiological', 'Animals', 'Carbocyanines', 'Culture Media', 'DNA, Bacterial', 'DNA, Complementary', 'Enzymes', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Lactobacillus helveticus', 'Metabolic Networks and Pathways', 'Milk', 'Molecular Sequence Data', 'Nucleic Acid Hybridizatio... | 17,322,329 | [['G07.025', 'G16.012.500'], ['B01.050'], ['D02.455.326.397.300'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D08.811'], ['E05.393.332'], ['G05.308.300'], ['B03.353.750.450.475.400', 'B03.510.460.400.410.475.475.400', 'B03.510.55... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Development of fetal rat pancreatic islet A cells. A quantitative and immunocytochemical study. | OBJECTIVE: To perform a detailed quantitative immunocytochemical study of the development of fetal rat pancreatic islet A cells.METHODS: Pancreases were obtained from 19 and 21-day- old fetal rats. Ten rats were used per each group. Non-fasting blood glucose levels were measured to confirm that the animals were normogl... | ['Animals', 'Cell Count', 'Cell Size', 'Female', 'Gestational Age', 'Glucagon-Secreting Cells', 'Immunohistochemistry', 'Islets of Langerhans', 'Rats', 'Saudi Arabia'] | 16,951,764 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.325'], ['G07.345.500.325.235.968', 'G08.686.320'], ['A03.734.414.065', 'A06.300.414.043', 'A06.390.087', 'A11.382.625.064', 'A11.436.294.064'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Use of the bougie in simulated difficult intubation. 2. Comparison of single-use bougie with multiple-use bougie. | We studied the success rates for tracheal intubation in 32 healthy, anaesthetised patients during simulated grade IIIa laryngoscopy, randomised to either the multiple-use or the single-use bougie. Success rates (primary end-point) and times taken (secondary end-point) to achieve tracheal intubation were recorded. The m... | ['Adolescent', 'Adult', 'Aged', 'Anesthesia, General', 'Disposable Equipment', 'Equipment Reuse', 'Female', 'Humans', 'Intubation, Intratracheal', 'Laryngoscopy', 'Male', 'Middle Aged', 'Time Factors'] | 12,911,356 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E03.155.197'], ['E07.252'], ['E05.328', 'N06.850.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['M01.060.116.630'], ['G01.910.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High power ultra-widely tuneable femtosecond pulses from a non-collinear optical parametric oscillator (NOPO). | We present an ultra-widely tunable non-collinear optical parametric oscillator with an average output power of more than 3 W and a repetition frequency of 34 MHz. The system is pumped by the second harmonic of a femtosecond Yb:KLu(WO4)2 thin-disk laser oscillator. The wavelength of the signal pulse can be rapidly tuned... | ['Equipment Design', 'Infrared Rays', 'Lasers, Dye', 'Light', 'Optics and Photonics', 'Oscillometry'] | 22,274,438 | [['E05.320'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.770.578.552', 'G16.500.275.063.725.525.400', 'G16.500.750.775.525.400', 'N06.230.300.100.725.525.400'], ['E07.632.490.230', 'E07.710.520.230'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['H01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Coexistence of three specialist aphids on common milkweed, Asclepias syriaca. | Coexistence of host-specific herbivores on plants is believed to be governed by interspecific interactions, but few empirical studies have systematically unraveled these dynamics. We investigated the role of several factors in promoting coexistence among the aphids Aphis nerii, Aphis asclepiadis, and Myzocallis asclepi... | ['Animals', 'Ants', 'Aphids', 'Asclepias', 'Feeding Behavior', 'Host-Parasite Interactions', 'Predatory Behavior', 'Species Specificity', 'Spiders'] | 18,724,729 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['B01.050.500.131.617.412.165'], ['B01.650.940.800.575.912.250.456.500.153'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G16.527.200.400'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['G16.824'], ['B01.050.500.131.166.803']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection and differentiation of coccidian oocysts by real-time PCR and melting curve analysis. | Rapid and reliable detection and identification of coccidian oocysts are essential for animal health and foodborne disease outbreak investigations. Traditional microscopy and morphological techniques can identify large and unique oocysts, but they are often subjective and require parasitological expertise. The objectiv... | ['Animals', 'Cats', 'Cattle', 'Coccidia', 'DNA Primers', 'DNA, Protozoan', 'Feces', 'Humans', 'Oocysts', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Swine', 'Transition Temperature'] | 21,506,835 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.500.380.271'], ['B01.043.075.189'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.442'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.870.740.600', 'B05.500.675', 'B05.775.740.600'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Reliability of an Online Geriatric Assessment Procedure Using the interRAI Acute Care Assessment System. | OBJECTIVES: To determine whether geriatric triage decisions made using a comprehensive geriatric assessment (CGA) performed online are less reliable than face-to-face (FTF) decisions.DESIGN: Multisite noninferiority prospective cohort study. Two specialist geriatricians assessed individuals sequentially referred for an... | ['Aged', 'Australia', 'Female', 'Geriatric Assessment', 'Hospitalization', 'Humans', 'Internet', 'Male', 'Prognosis', 'Prospective Studies', 'Referral and Consultation', 'Reproducibility of Results', 'Surveys and Questionnaires', 'Telemedicine', 'Triage'] | 28,832,897 | [['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E01.789'], ['E05.3... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
The founding of Mauritian endemic coffee trees by a synchronous long-distance dispersal event. | The stochastic process of long-distance dispersal is the exclusive means by which plants colonize oceanic islands. Baker's rule posits that self-incompatible plant lineages are unlikely to successfully colonize oceanic islands because they must achieve a coordinated long-distance dispersal of sufficiently numerous indi... | ['Bayes Theorem', 'Coffea', 'Genes, Plant', 'Genotype', 'Mauritius', 'Models, Genetic', 'Phylogeny', 'Population Dynamics', 'Seed Dispersal', 'Sequence Analysis, DNA'] | 24,797,428 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['B01.650.940.800.575.912.250.456.937.275'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.380'], ['Z01.639.520.520'], ['E05.599.395.397'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['I01.240.600', 'N01.224.625', 'N06.850.505.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
The Weekend Effect in AAA Repair. | BACKGROUND: Conflicting reports exist regarding whether patients undergoing surgery on the weekend or later in the week experience worse outcomes.METHODS: We identified patients undergoing abdominal aortic aneurysm (AAA) repair in the Vascular Quality Initiative between 2009 and 2017 [n = 38,498; 30,537 endovascular an... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm, Abdominal', 'Aortic Rupture', 'Blood Vessel Prosthesis Implantation', 'Endovascular Procedures', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Survival Rate', 'Time Factors', 'Treatment Outcome'] | 31,082,917 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of transforming growth factor-beta1 on renal extracellular matrix components and their regulating proteins. | Transforming growth factor-beta1 (TGF-beta1) is widely regarded as a potent fibrogenic renal growth factor. In cell culture, TGF-beta1 has been shown to increase various extracellular matrix (ECM) proteins and tissue inhibitors of metalloproteinases (TIMP), while decreasing matrix metalloproteinases (MMP), providing th... | ['Animals', 'Base Sequence', 'Blotting, Northern', 'Dose-Response Relationship, Drug', 'Enzyme-Linked Immunosorbent Assay', 'Extracellular Matrix Proteins', 'Humans', 'Kidney', 'Kidney Function Tests', 'Male', 'Membrane Proteins', 'Metalloendopeptidases', 'Molecular Sequence Data', 'Peptidylprolyl Isomerase', 'Polymera... | 10,505,687 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.860.300'], ['B01.050.150.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Functional connection between the Clb5 cyclin, the protein kinase C pathway and the Swi4 transcription factor in Saccharomyces cerevisiae. | The rsf12 mutation was isolated in a synthetic lethal screen for genes functionally interacting with Swi4. RSF12 is CLB5. The clb5 swi4 mutant cells arrest at G(2)/M due to the activation of the DNA-damage checkpoint. Defects in DNA integrity was confirmed by the increased rates of chromosome loss and mitotic recombina... | ['Blotting, Western', 'Cell Cycle', 'Chromosomes, Fungal', 'Cyclin B', 'DNA, Fungal', 'DNA-Binding Proteins', 'Flow Cytometry', 'Fluorescent Antibody Technique, Indirect', 'Hydroxyurea', 'Immunoprecipitation', 'Mutation', 'Protein Kinase C', 'Recombination, Genetic', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisia... | 16,118,191 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['A11.284.187.360', 'A19.311', 'G05.360.162.360'], ['D12.644.360.262.120', 'D12.776.167.218.120', 'D12.776.476.262.120'], ['D13.444.308.300'], ['D12.776.260'], ['E01.370.225.500.363.342', 'E01.370.225.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[New class of RP4 plasmid mutations inducing a mucoid-type of Escherichia coli K-12 cell growth]. | A new class of mutations is described which induce mucoid growth of Escherichia coli K-12. Unlike classical capR and capS mutations, the mucoid phenotype of colonies of the cap forms obtained is determined by mutations in genomes of thermosensitive plasmids pEG1 and RP1-6Repts12, derivates of the RP1 Inc P1 Ap Tc Km fa... | ['Conjugation, Genetic', 'Escherichia coli', 'Genes, Bacterial', 'Mutation', 'Phenotype', 'Plasmids', 'Polysaccharides, Bacterial', 'Transformation, Bacterial'] | 7,049,833 | [['G05.728.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.365.590'], ['G05.695'], ['G05.360.600'], ['D09.698.718', 'D23.050.161.616'], ['E05.393.350.810.500', 'G05.728.860.500', 'G05.728.865.820', 'G06.099.850']... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Instrumentation for bedside analysis of swallowing disorders. | Disordered swallowing, or dysphagia, is a common problem seen in patients undergoing treatment for cancer, stroke and neurodegenerative illnesses. This disease is associated with aspiration-induced chest infections. The methods currently used for diagnosis, however, are qualitative or based on expensive equipment. Swal... | ['Acceleration', 'Deglutition Disorders', 'Diagnosis, Computer-Assisted', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Humans', 'Male', 'Monitoring, Physiologic', 'Point-of-Care Systems', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Transducers', 'Young Adult'] | 21,096,774 | [['G01.482.107'], ['C06.405.117.119', 'C09.775.174'], ['E01.158', 'L01.313.500.750.100.158'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N04.590.874'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Further investigation of the pathogenicity, immunogenicity and stability of precocious Eimeria acervulina. | Attenuated lines of Eimeria acervulina were isolated between 62 and 72 h post-infection from the Houghton (H) strain. The inoculation of small numbers of oocysts of precocious (HP) lines gave substantial protection to Light Sussex chicks kept on litter against challenge with the virulent H strain. The precocious trait ... | ['Animals', 'Chickens', 'Eimeria', 'Immunity', 'Immunization'] | 6,877,863 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.043.075.189.250.250.250'], ['G12.450'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Systematic review of visual rehabilitation interventions for oculomotor deficits in patients with brain injury. | Purpose: Secondary to brain injury, many people develop eye movement disorders (oculomotor deficits). To clarify, optimize, and standardize the development of oculomotor rehabilitation programs, we systematically reviewed the literature on vision rehabilitation interventions for oculomotor deficits in brain injury, foc... | ['Brain Injuries', 'Clinical Trials as Topic', 'Eye Movements', 'Humans', 'Ocular Motility Disorders'] | 31,455,098 | [['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.758', 'C10.292.562', 'C11.590']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
MAESTRO--multi agent stability prediction upon point mutations. | BACKGROUND: Point mutations can have a strong impact on protein stability. A change in stability may subsequently lead to dysfunction and finally cause diseases. Moreover, protein engineering approaches aim to deliberately modify protein properties, where stability is a major constraint. In order to support basic resea... | ['Disulfides', 'Internet', 'Point Mutation', 'Protein Stability', 'Proteins', 'User-Computer Interface'] | 25,885,774 | [['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['L01.224.230.110.500'], ['G05.365.590.675'], ['G02.111.700'], ['D12.776'], ['L01.224.900.910']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Transitional tumor of the right kidney with vena cava thrombus. Report of a case]. | Transitional cell carcinoma of the kidney with vena caval tumor thrombus is a rarity with 12 cases reported in the literature. We review in this article the elements of the diagnosis and possible treatment modalities. | ['Aged', 'Carcinoma, Transitional Cell', 'Humans', 'Kidney Neoplasms', 'Male', 'Neoplastic Cells, Circulating', 'Vena Cava, Inferior'] | 8,369,829 | [['M01.060.116.100'], ['C04.557.470.200.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['A11.642', 'C04.697.650.900', 'C23.550.727.650.900'], ['A07.015.908.949.648']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Three dimensional dental epithelial-mesenchymal constructs of predetermined size and shape for tooth regeneration. | While it is known that precise dental epithelial-mesenchymal (DE-DM) cell interactions provide critical functions in tooth development, reliable methods to establish proper DE-DM cell interactions for tooth regeneration have yet to be established. To address this challenge, and to generate bioengineered teeth of predet... | ['Adolescent', 'Animals', 'Cell Separation', 'Coculture Techniques', 'Epithelium', 'Fluorescence', 'Fluorescent Antibody Technique', 'Guided Tissue Regeneration', 'Humans', 'Male', 'Mesoderm', 'Microscopy, Confocal', 'Organ Size', 'Rats', 'Sus scrofa', 'Tissue Engineering', 'Tissue Scaffolds', 'Tooth'] | 20,682,455 | [['M01.060.057'], ['B01.050'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.481.500.374'], ['A10.272'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
gp96-peptide vaccination of mice against intracellular bacteria. | This work demonstrates that gp96 preparations isolated from cells infected with intracellular bacteria induce cytotoxic T-lymphocyte responses and confer protection. Our findings extend previous reports on the immunogenicity of gp96-associated peptides to antigens derived from intracellular bacteria. Immunization with ... | ['Animals', 'CD8-Positive T-Lymphocytes', 'Heat-Shock Proteins', 'Listeria monocytogenes', 'Listeriosis', 'Mice', 'Mice, Inbred C57BL', 'Mycobacterium tuberculosis', 'Peptides', 'Spleen', 'Tuberculosis', 'Vaccination'] | 11,349,093 | [['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D12.776.580.216'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['C01.150.252.410.514'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg). | The study evaluated the effect of DHA 625 mg in women who experience menopausal symptoms, on sexuality and quality of life (QoL), and on the auditory brainstem response (ABR). Forty-two perimenopausal women were enrolled. The Kupperman Index (KI) was used to evaluate menopause symptoms. The Short Form-36 (SF-36), Femal... | ['Docosahexaenoic Acids', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Humans', 'Middle Aged', 'Perimenopause', 'Quality of Life', 'Sexual Dysfunction, Physiological'] | 28,562,107 | [['D10.212.302.380.410.210', 'D10.251.355.337.250', 'D10.627.430.450.375'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.157.500.562', 'G08.686.841.249.500.562'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Esophageal foreign bodies. Our ten years of experience]. | OBJECTIVE: To study the management of esophageal foreign bodies.MATERIAL AND METHODS: A retrospective study was made of all rigid esophagoscopies performed for suspected foreign bodies in the esophagus by an otolaryngology department for ten years.RESULTS: Rigid esophagoscopy was performed for suspected foreign bodies ... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Esophagoscopy', 'Esophagus', 'Female', 'Foreign Bodies', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Retrospective Studies'] | 12,825,244 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['A03.556.875.500'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A case of sudden cardiac death in connection with Salmonella typhimurium infection. | A case of fatal myocarditis in a 24-year-old otherwise healthy man is described. It was possible to cultivate Salmonella typhimurium from the alimentary tract, the blood, the liver and skeletal muscles. The possibility of a solitary myocarditis with fatal outcome due to Salmonella typhimurium infection is discussed. Su... | ['Adult', 'Death, Sudden', 'Humans', 'Male', 'Myocarditis', 'Salmonella Infections', 'Salmonella typhimurium'] | 7,009,351 | [['M01.060.116'], ['C23.550.260.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.238.625'], ['C01.150.252.400.310.821'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of metoclopramide and metoclopramide/dopamine on blood pressure and insulin release in normotensive, hypertensive, and type 2 diabetic subjects. | The objective is to determine cardiovascular and insulin release effects under metoclopramide (MTC) and dopamine (DA) infusion by using an acute comparative design with the intravenous infusion of both drugs. We evaluated 15 normal (normotensive and normoglycemic) subjects, 13 hypertensive, and 15 type 2 diabetic subje... | ['Adult', 'Blood Pressure', 'Cold Temperature', 'Diabetes Mellitus, Type 2', 'Dopamine', 'Dopamine Agents', 'Dopamine Antagonists', 'Drug Interactions', 'Endothelium, Vascular', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Infusions, Intravenous', 'Insulin', 'Lipids', 'Male', 'Metoclopramide', 'Middle Aged', 'Rec... | 20,216,207 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['C18.452.394.750.149', 'C19.246.300'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dynamic evolution of mitochondrial ribosomal proteins in Holozoa. | We studied the highly dynamic evolution of mitochondrial ribosomal proteins (MRPs) in Holozoa. Most major clades within Holozoa are characterized by gains and/or losses of MRPs. The usefulness of gains of MRPs as rare genomic changes in phylogenetics is undermined by the high frequency of secondary losses. However, phy... | ['Amoeba', 'Animals', 'Bacterial Proteins', 'Ctenophora', 'DNA, Mitochondrial', 'Evolution, Molecular', 'Gene Transfer, Horizontal', 'Genome, Mitochondrial', 'Genomics', 'Mitochondria', 'Mitochondrial Proteins', 'Phylogeny', 'RNA, Ribosomal', 'Ribosomal Proteins', 'Ribosomes', 'Sequence Analysis, DNA'] | 24,631,858 | [['B01.046.500.100.700.089'], ['B01.050'], ['D12.776.097'], ['B01.050.500.325'], ['D13.444.308.283.225'], ['G05.045.250', 'G16.075.250'], ['G05.728.390'], ['G05.360.340.360'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.575'], ['G05.697', 'G16.075.605', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Cardiovascular morbidity-mortality associated to ankle-brachial index in the general population. | BACKGROUND AND OBJECTIVES: Abnormal ankle-brachial index (ABI) is associated with a high risk of cardiovascular disease. This study has aimed to investigate the association between low ABI and risk of cardiovascular death in a general population attended in a primary care center.PATIENTS AND METHODS: A total of 1,361 v... | ['Aged', 'Ankle Brachial Index', 'Cardiovascular Diseases', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peripheral Arterial Disease', 'Risk Assessment', 'Risk Factors'] | 24,119,392 | [['M01.060.116.100'], ['E01.370.370.140.049'], ['C14'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.907.137.126.307.500', 'C14.907.617.671'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['E05.318.740.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantitative multiplexed simulated-cell identification by SERS in microfluidic devices. | A reliable identification of cells on the basis of their surface markers is of great interest for diagnostic and therapeutic applications. We present a multiplexed labeling and detection strategy that is applied to four microparticle populations, each mimicking cellular or bacterial samples with varying surface concent... | ['Biomarkers', 'Lab-On-A-Chip Devices', 'Spectrum Analysis, Raman'] | 26,404,699 | [['D23.101'], ['E07.305.343.500'], ['E05.196.822.860', 'E05.196.867.890']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection. | Elderly people are at high risk for influenza-related morbidity and mortality due to progressive immunosenescence. While toll-like receptor (TLR) agonist containing adjuvants, and other adjuvants, have been shown to enhance influenza vaccine-induced protective responses, the mechanisms underlying how these adjuvanted v... | ['Adjuvants, Immunologic', 'Aged', 'Animals', 'Antibodies, Viral', 'Cells, Cultured', 'Dendritic Cells', 'Female', 'Glucosides', 'Humans', 'Immunity', 'Immunization', 'Influenza A Virus, H1N1 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Lipid A', 'Mice', 'Mice, Inbred C57BL', 'Orthomyxoviridae Infections', 'Tol... | 29,515,589 | [['D27.505.696.477.067'], ['M01.060.116.100'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.251'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D09.408.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['E... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Plasma cholesteryl ester transfer protein mass and phospholipid transfer protein activity are associated with leptin in type 2 diabetes mellitus. | Adipose tissue contributes to plasma levels of lipid transfer proteins and is also the major source of plasma adipokines. We hypothesized that plasma cholesteryl ester transfer protein (CETP) mass, phospholipid transfer protein (PLTP) activity and cholesteryl ester transfer (CET, a measure of CETP action) are determine... | ['Blood Proteins', 'Cholesterol Ester Transfer Proteins', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Leptin', 'Lipids', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Phospholipid Transfer Proteins'] | 17,185,032 | [['D12.776.124'], ['D09.400.430.750', 'D12.776.124.197', 'D12.776.157.165', 'D12.776.395.199'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['D10'], ['M01.060.116... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacological characterization of tachykinin-stimulated inositol phospholipid hydrolysis in peripheral tissues. | 1. Tachykinin-stimulated inositol phospholipid hydrolysis was examined in slices of rat parotid gland, hamster urinary bladder and guinea-pig ileum longitudinal muscle. 2. In the presence of lithium, substance P and other naturally-occurring and synthetic tachykinins induced large, dose-dependent increases in [3H]-inos... | ['Animals', 'Cricetinae', 'Guinea Pigs', 'Hydrolysis', 'Ileum', 'In Vitro Techniques', 'Muscles', 'Parotid Gland', 'Peptide Fragments', 'Peptides, Cyclic', 'Phosphatidylinositols', 'Pyrrolidonecarboxylic Acid', 'Rats', 'Substance P', 'Tachykinins', 'Urinary Bladder'] | 1,707,702 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.550'], ['G02.380'], ['A03.556.124.684.249', 'A03.556.249.124'], ['E05.481'], ['A02.633', 'A10.690'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['D12.644.541'], ['D04.345.566', 'D12.644.641'], ['D10.570.755.375.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Kidney failure after ectracorporeal circulation in cardiac surgery]. | The renal function of 113 patients undergoing cardiac surgery under ECC was studied. In 32 p. 100 of the cases renal involvement was noted which was moderate in 18 p. 100 of the cases, severe in 10 p. 100 of the cases and anuric in 4 p. 100 of the cases. Valvular surgery was complicated once in every three cases by ren... | ['Acute Kidney Injury', 'Adolescent', 'Adult', 'Aged', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Coronary Artery Bypass', 'Extracorporeal Circulation', 'Heart Defects, Congenital', 'Heart Valve Prosthesis', 'Humans', 'Kidney', 'Middle Aged', 'Myocardial Infarction'] | 16,549 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E04.292'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['E07.6... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of a novel simian immunodeficiency virus from guereza colobus monkeys (Colobus guereza) in Cameroon: a new lineage in the nonhuman primate lentivirus family. | Exploration of the diversity among primate lentiviruses is necessary to elucidate the origins and evolution of immunodeficiency viruses. During a serological survey in Cameroon, we screened 25 wild-born guereza colobus monkeys (Colobus guereza) and identified 7 with HIV/SIV cross-reactive antibodies. In this study, we ... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Viral', 'Base Sequence', 'Cameroon', 'Cloning, Molecular', 'Colobus', 'Female', 'HIV Antibodies', 'HIV Envelope Protein gp120', 'Lentivirus', 'Male', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'Phylogeny', 'Polymerase Chain Reaction', 'Sequence Alignment', 'Sequ... | 11,134,299 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.058.290.100.110'], ['E05.393.220'], ['B01.050.150.900.649.313.988.400.112.199.150.150'], ['D12.776.124... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Genotoxicity detected in wild mice living in a highly polluted wetland area in south western Spain. | A field study was carried out in the south of the Iberian Peninsula in an industrial area in the neighbourhood of Huelva city, SW Spain, and in a natural area (Do?ana National Park) for comparison, to estimate the genetic risk induced by environmental pollution in wild mice. Genotoxic effects in a sentinel organism, th... | ['Animals', 'Comet Assay', 'DNA Damage', 'Environmental Exposure', 'Environmental Monitoring', 'Environmental Pollution', 'Food Chain', 'Industrial Waste', 'Mice', 'Mining', 'Mutagens', 'Spain', 'Wetlands'] | 17,949,869 | [['B01.050'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.850.460'], ['G16.500.275.157.250', 'N06.230.124.250'], ['D20.944.420', 'N06.850.460.710.420'], ['B01.050.150.900.649.313.992.635.505.500... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[Isolation and identification of a newbacterial pathogen infecting larvae of honeybee (Apismellifera ) Perish]. | A bacteroidal disease of honeybee (Apis mellifera ) larvae was found in some regions of Zhejiang Province, China , in early spring 2005. The diseased larvae lost its shine, became yellow and rotted when serious. This symptom was different to any bacteroidal disease of honeybee larval been reported. So, it is considered... | ['Animals', 'Bees', 'Enterococcus faecium', 'Larva', 'Phylogeny', 'RNA, Ribosomal, 16S'] | 17,302,168 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['B03.353.750.250.250.300', 'B03.510.550.250.250.300'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Association between interleukin 6 promoter variants and chronic hepatitis B progression. | Interleukin 6 (IL6) plays an essential role in the regulation of immune response to chronic disease. In this study, the three known single nucleotide polymorphisms (SNPs) in the IL6 promoter region were genotyped in a large chronic hepatitis B cohort to evaluate the effects of IL6 promoter variants. The single base ext... | ['Aged', 'Alleles', 'Asian Continental Ancestry Group', 'Female', 'Genetic Variation', 'Haplotypes', 'Hepatitis B, Chronic', 'Humans', 'Interleukin-6', 'Korea', 'Linkage Disequilibrium', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Promoter Regions, Genetic'] | 12,754,410 | [['M01.060.116.100'], ['G05.360.340.024.340.030'], ['M01.686.508.200'], ['G05.365'], ['G05.380.360'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The protective effect of K+ channel openers on beta-amyloid induced cerebrovascular endothelial dysfunction. | Amyloid angiopathy is characterized by amyloid beta-peptide (A beta) deposition and may contribute to the cerebrovascular abnormalities that precede the onset of Alzheimer's Disease (AD). That aberrant potassium (K+) channel function occurs in AD patients is supported by deleterious effects of A beta on normal fibrobla... | ['Acetylcholine', 'Aging', 'Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Aorta', 'Aorta, Thoracic', 'Cells, Cultured', 'Cerebral Arteries', 'Cytoprotection', 'Endothelium, Vascular', 'Fibroblasts', 'Free Radicals', 'Male', 'Nitric Oxide', 'Potassium Channels', 'Rats', 'Rats, Sprague-Dawley'] | 10,406,005 | [['D02.092.211.111'], ['G07.345.124'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['A07.015.114.056'], ['A07.015.114.056.372'], ['A11.251'], ['A07.015.114.228'], ['G07.690.773.500'], ['A07.015.700.500', 'A10.272.491.355'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Quality Improvement Project to Improve Evidence-Based Inhaled Nitric Oxide Use. | BACKGROUND: Inhaled nitric oxide (INO) reduces extracorporeal membrane oxygenation (ECMO) use in term and near-term neonates with persistent pulmonary hypertension of the newborn; however, its overutilization is increasing. We hypothesized that implementing a shared baseline protocol would safely improve evidence-based... | ['Administration, Inhalation', 'Bronchodilator Agents', 'Evidence-Based Medicine', 'Extracorporeal Membrane Oxygenation', 'Female', 'Health Plan Implementation', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Intensive Care Units, Neonatal', 'Male', 'Nitric Oxide', 'Quality Improvement', 'Respiratory Insufficiency'... | 28,974,647 | [['E02.319.267.050'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['H02.249.750', 'H02.403.200.400'], ['E02.880.301', 'E04.292.451'], ['N03.349.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['N02.278.388.493.390.380'], ['D01.339.387', 'D01.625.550.500'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Potential utility of rhIGF-1 in neuromuscular and/or degenerative disease. | Neuromuscular/neurodegenerative disorders, such as the death of spinal cord motor neurons in amyotrophic lateral sclerosis (ALS) or the degeneration of spinal cord motor neuron axons in certain peripheral neuropathies, present a unique opportunity for therapeutic intervention with neurotrophic proteins. We have found t... | ['Amyotrophic Lateral Sclerosis', 'Animals', 'Cells, Cultured', 'Choline O-Acetyltransferase', 'Disease Models, Animal', 'Female', 'Humans', 'Insulin-Like Growth Factor I', 'Mice', 'Motor Neurons', 'Nerve Degeneration', 'Rats', 'Rats, Sprague-Dawley', 'Recombinant Proteins', 'Spinal Cord'] | 8,866,126 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['A11.251'], ['D08.811.913.050.134.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal obesity as a risk factor for early childhood type 1 diabetes: a nationwide, prospective, population-based case-control study. | AIMS/HYPOTHESIS: Genetic and environmental factors are believed to cause type 1 diabetes. The aim of this study was to investigate the influence of maternal BMI and gestational weight gain on the subsequent risk of childhood type 1 diabetes.METHODS: Children in the Swedish National Quality Register for Diabetes in Chil... | ['Adolescent', 'Adult', 'Age of Onset', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Infant', 'Male', 'Obesity', 'Prospective Studies', 'Risk Factors', 'Young Adult'] | 29,098,322 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'],... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Initial clinical experience with a new percutaneous peripheral atherectomy device for the treatment of femoro-popliteal stenoses]. | BACKGROUND: Evaluation of the efficacy and safety of a new 7F-atherectomy device (30-day endpoint) for the treatment of short and mid-length arterial lesions with a reference diameter of 2.5-7 mm.MATERIAL AND METHODS: Fifty-eight femoto-popliteal stenoses in 46 patients (67% male, mean age 66 +/- 9 years) with chronic ... | ['Aged', 'Angiography', 'Angioplasty, Balloon', 'Arterial Occlusive Diseases', 'Atherectomy', 'Catheterization', 'Data Interpretation, Statistical', 'Female', 'Femoral Artery', 'Follow-Up Studies', 'Humans', 'Intermittent Claudication', 'Leg', 'Male', 'Middle Aged', 'Popliteal Artery', 'Postoperative Care', 'Prospectiv... | 14,712,409 | [['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137'], ['E02.148.050.120', 'E04.100.814.529.124.120', 'E04.502.382.124.120', 'E05.157.016.120'], ['E02.148', 'E05.157'], ['E05.245.380', 'E05.318.740.300'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The impact of pelvic and lower extremity fractures on the incidence of lower extremity deep vein thrombosis in high-risk trauma patients. Winner of the Best Paper Award from the Gold Medal Forum. | Lower extremity fractures (LEFx) and pelvic fractures (PFx) are believed to increase the risk of lower extremity deep vein thrombosis (LEDVT). We studied trauma patients at high risk for LEDVT to determine whether an increased incidence of LEDVT was associated with LEFx and/or PFx. From January 1995 through December 19... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Awards and Prizes', 'Female', 'Femoral Fractures', 'Fractures, Bone', 'Humans', 'Incidence', 'Leg Injuries', 'Male', 'Middle Aged', 'Pelvic Bones', 'Retrospective Studies', 'Risk', 'Tibial Fractures', 'Ultrasonography', 'Venous Thrombosis'] | 12,852,501 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['K01.150'], ['C26.404.061', 'C26.558.276'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C26.558'], ['M01... | ['Named Groups [M]', 'Humanities [K]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Terapeutic Potential of Microencapsulated Sertoli Cells in Huntington Disease. | INTRODUCTION: Immune dysfunction, promoted by pro-inflammatory cytokines, plays a pivotal role in neurodegeneration associated with Huntington's disease.AIMS: The aim of this study was to investigate the emerging immunoregulatory and antiinflammatory properties of Sertoli cells in Huntington's disease.METHODS: The expe... | ['Animals', 'Animals, Newborn', 'Apoptosis', 'Corpus Striatum', 'Cyclooxygenase 2', 'Cytokines', 'Disease Models, Animal', 'Drug Compounding', 'Female', 'Gene Expression Regulation', 'Humans', 'Huntingtin Protein', 'Huntington Disease', 'Male', 'Mice', 'Mice, Transgenic', 'Motor Activity', 'Nitric Oxide Synthase Type I... | 27,225,886 | [['B01.050'], ['B01.050.050.282'], ['G04.146.954.035'], ['A08.186.211.200.885.287.249.487'], ['D08.811.600.720.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.916.270'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.441'], ['C1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Platelet thromboxane formation capacity after ethanol withdrawal in chronic alcoholics. | Collagen-, arachidonate- and ADP-stimulated platelet thromboxane B2 (TXB2) formation was studied in platelet-rich plasma (PRP) of 14 alcoholics, 7 of whom had a biopsy-verified alcoholic fatty liver. On admission for detoxication, the alcoholics showed decreased platelet count and aggregability (p less than 0.001) as c... | ['Adenosine Diphosphate', 'Adult', 'Alcoholism', 'Arachidonic Acid', 'Arachidonic Acids', 'Bleeding Time', 'Blood Platelets', 'Collagen', 'Ethanol', 'Female', 'Fibrinogen', 'Humans', 'Liver Diseases, Alcoholic', 'Male', 'Middle Aged', 'Platelet Aggregation', 'Platelet Count', 'Serum Albumin', 'Substance Withdrawal Synd... | 3,141,251 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['E01.370.225.625.625.100', 'E05.200.625.625.100', 'G09.188.087'], ['A11.118.18... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Region specific gene expressions in the central nervous system of the ascidian embryo. | The vertebrate brain is regionalized during development into forebrain, midbrain and hindbrain. Fibroblast growth factor 8 (FGF8) is expressed in the midbrain/hindbrain boundary (MHB) and functions as an organizer molecule. Previous studies demonstrated that the brain of basal chordates or ascidians is also regionalize... | ['Amino Acid Sequence', 'Animals', 'Brain', 'DNA-Binding Proteins', 'Fibroblast Growth Factors', 'Homeodomain Proteins', 'In Situ Hybridization', 'Molecular Sequence Data', 'Nuclear Proteins', 'Otx Transcription Factors', 'PAX2 Transcription Factor', 'PAX5 Transcription Factor', 'Trans-Activators', 'Transcription Facto... | 12,617,820 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A08.186.211'], ['D12.776.260'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['D12.776.260.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['L01.453.245.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Slit-lamp fluid-gas exchange and other office procedures following vitreoretinal surgery. | Many complicated postoperative vitreoretinal cases require reoperations. It is possible to perform some of these procedures outside the operating room. We describe examining room techniques for fluid-gas exchange, fluid and gas aspiration, and adherent vitreous strand removal. We also discuss a slit-lamp technique for ... | ['Anesthesia, Local', 'Aphakia, Postcataract', 'Cornea', 'Humans', 'Hyaluronic Acid', 'Intraocular Pressure', 'Needles', 'Operating Rooms', 'Postoperative Care', 'Postoperative Complications', 'Posture', 'Retina', 'Suction', 'Vitrectomy'] | 4,015,489 | [['E03.155.086.231'], ['C11.510.103.110'], ['A09.371.060.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['G14.440'], ['E07.612'], ['N02.278.388.700'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['C23.550.767'], ['G11.427.695'], ['A09.371.729'], ['E04.237.890'], ['E04.540.96... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Experimental test of spatial updating models for monkey eye-head gaze shifts. | How the brain maintains an accurate and stable representation of visual target locations despite the occurrence of saccadic gaze shifts is a classical problem in oculomotor research. Here we test and dissociate the predictions of different conceptual models for head-unrestrained gaze-localization behavior of macaque mo... | ['Animals', 'Biofeedback, Psychology', 'Eye Movements', 'Fixation, Ocular', 'Head Movements', 'Humans', 'Macaca', 'Photic Stimulation', 'Psychomotor Performance', 'Saccades'] | 23,118,883 | [['B01.050'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['G11.427.410.140', 'G14.350'], ['G14.350.253'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['E05.723.729'], ['F02.808', 'G11.427.700', 'G11.561.660'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Image reconstruction in electrical impedance tomography based on genetic algorithm]. | Image reconstruction in electrical impedance tomography (EIT) is a highly ill-posed, non-linear inverse problem. The modified Newton-Raphson (MNR) iteration algorithm is deduced from the strictest theoretic analysis. It is an optimization algorithm based on minimizing the object function. The MNR algorithm with regular... | ['Algorithms', 'Electric Impedance', 'Image Processing, Computer-Assisted', 'Nonlinear Dynamics', 'Tomography'] | 12,744,177 | [['G17.035', 'L01.224.050'], ['G01.358.500.249.277.350'], ['L01.224.308'], ['E05.599.850', 'H01.548.675'], ['E01.370.350.825']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. | BACKGROUND & AIMS: Prostaglandins are synthesized by cyclooxygenases (COX)-1 and -2. The expression and cellular localization of COX-1 and COX-2 in normal human colon and inflammatory bowel disease (IBD) surgical resections were studied.METHODS: COX-1 and COX-2 protein expression and cellular localization were assessed... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colitis', 'Colitis, Ulcerative', 'Colon', 'Crohn Disease', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Enzyme Induction', 'Female', 'Humans', 'Ileitis', 'Inflammatory Bowel Diseases', 'Intestinal Mucosa', 'Isoenzymes', 'Male', 'Membrane Proteins', 'Middle Aged', 'Prostaglandin-Endop... | 9,679,035 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C06.405.205.265', 'C06.405.469.158.188'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['D08.811.600.720.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Added soluble fiber enhances the satiating power of low-energy-density liquid yogurts. | BACKGROUND: Low-energy-density foods with high satiating power may be useful tools for weight management. Energy density of yogurts can range from 0.4 to 1.8 kcal/g.OBJECTIVE: To test the effects of added inulin, a soluble fiber, on the satiating properties of low-energy-density and high-energy-density yogurt beverages... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Beverages', 'Citrus sinensis', 'Cross-Over Studies', 'Dietary Fats', 'Dietary Fiber', 'Energy Intake', 'Female', 'Humans', 'Inulin', 'Male', 'Nutritive Value', 'Obesity', 'Satiation', 'Solubility', 'Yogurt', 'Young Adult'] | 19,857,627 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G07.203.100', 'J02.200'], ['B01.650.940.800.575.912.250.875.177.769'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.301.416', 'G07.203.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Case management decision support tools: predictive risk report or health risk assessment? | It is unclear whether health risk assessment (HRA) or claims-based risk modeling is a superior indicator of the need for case management in Medicaid adults with disabilities. This is a prospective cohort study designed to compare the use of a claims-based Predictive Risk Report (PRR) to a HRA in a Medicaid Supplemental... | ['Case Management', 'Cohort Studies', 'Decision Support Systems, Management', 'Health Status Indicators', 'Humans', 'Interviews as Topic', 'Medicaid', 'Prospective Studies', 'Risk Assessment', 'Surveys and Questionnaires', 'United States'] | 18,942,923 | [['N04.590.233.624.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N04.452.515.135'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.30... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Spatial arrangement of intra-nucleolar rDNA chromatin in amplified Xenopus oocyte nucleoli: structural changes precede the onset of rDNA transcription. | Amphibian oocyte nucleoli are a particular suited object for research on nucleolar chromatin organization. By selective rDNA amplification each pachytene oocyte nucleus accumulates 30 pg of extrachromosomal rDNA, this amount corresponds to 2 million rDNA copies. Following the selective amplification stage, the amplifie... | ['Animals', 'Cell Nucleolus', 'Chromatin', 'DNA, Ribosomal', 'Female', 'Kinetics', 'Microscopy, Electron', 'Oocytes', 'Oogenesis', 'Transcription, Genetic', 'Xenopus laevis'] | 8,735,937 | [['B01.050'], ['A11.284.430.106.279.345.175'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308.475'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.515.402', 'E05.595.402'], ['A05.360.490.690.680', 'A11.497.497.600'], ['G04.152.650.249', 'G08.686.784.310.500'], ['G02.111.873... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Molecular typing of the pathogenic Yersinia enterocolitica strains with pulsed field gel electrophores isolated in China]. | OBJECTIVE: To investigate the epidemiological and molecular typing features of the pathogenic Yersinia enterocolitica strains isolated in China,using pulsed field gel electrophoresis(PFGE) and standardized PFGE method as well as typing database of Yersinia enterocolitica.METHODS: PFGE analysis was performed as Laborato... | ['China', 'Electrophoresis, Gel, Pulsed-Field', 'Humans', 'Yersinia enterocolitica'] | 17,172,107 | [['Z01.252.474.164'], ['E05.196.401.220', 'E05.301.300.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.450.425.900.300', 'B03.660.250.150.950.160']] | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
CT scan cerebral hemispheric asymmetries: predictors of recovery from aphasia. | Individual variations in anatomic cerebral asymmetries have been linked with specific neurodevelopmental processes, with patterns of cognitive ability, and with recovery from focal brain damage. The present study investigated relationships between cerebral asymmetries and recovery from aphasia. Aphasic patients (N = 25... | ['Aged', 'Aged, 80 and over', 'Aphasia', 'Cerebrovascular Disorders', 'Functional Laterality', 'Humans', 'Language', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 8,491,845 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['C10.228.140.300', 'C14.907.253'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E0... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Ganglion cells and retinopetal fibers of the larval lamprey retina: an HRP ultrastructural study. | The ultrastructure of ganglion cells and centrifugal fibers of the larval lamprey retinas were studied using horseradish peroxidase (HRP) as a marker. Larval ganglion cells were found both in the inner nuclear layer and the inner plexiform layer of the differentiated retina, and also were present in the undifferentiate... | ['Animals', 'Brain', 'Efferent Pathways', 'Fishes', 'Horseradish Peroxidase', 'Lampreys', 'Larva', 'Retina', 'Retinal Ganglion Cells', 'Visual Pathways'] | 2,586,814 | [['B01.050'], ['A08.186.211'], ['A08.612.380'], ['B01.050.150.900.493'], ['D08.811.682.732.512'], ['B01.050.150.900.493.559'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A09.371.729'], ['A08.675.650.850.875', 'A09.371.729.831.875', 'A11.671.650.850.875'], ['A08.612.220.860']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adolescent and adult differences in major depression symptom profiles. | BACKGROUND: Depression is the leading global cause of disability and often begins in adolescence. The genetic architecture and treatment response profiles for adults and adolescents differ even though identical criteria are used to diagnose depression across different age groups. There is no clear consensus on how thes... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Child', 'Depression', 'Depressive Disorder, Major', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Humans', 'Male', 'Middle Aged', 'Recurrence'] | 30,243,197 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['M01.060.406'], ['F01.145.126.350'], ['F03.600.300.375'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.291.937']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Application of HSV colour system in identification by colour of biological objects on the basis of microscopic images. | This paper demonstrates preliminary image processing with the aim of obtaining invariant signs for identification by colour. For this purpose we have used microscopic images of cell structures in coloured peripheral blood smears. The main parameter for the identification is the colouring of the respective cell structur... | ['Algorithms', 'Basophils', 'Blood Cells', 'Color', 'Coloring Agents', 'Eosinophils', 'Erythrocytes', 'Humans', 'Image Processing, Computer-Assisted', 'Leukocytes', 'Microscopy', 'Monocytes', 'Neutrophils', 'Pattern Recognition, Automated'] | 9,007,363 | [['G17.035', 'L01.224.050'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['A11.118', 'A15.145.229'], ['G01.590.540.199'], ['D27.720.233'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['A11.118.290', 'A11.443.240', 'A15.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Resection of a Posterior Mediastinal Tumor Using Intraoperative Motor Evoked Potential Monitoring;Report of a Case]. | A 20-year-old man with a posterior mediastinal tumor incidentally found on a chest X-ray was referred to our hospital. Chest computed tomography showed a 3 cm nodule located on the left side of the 10-11th thoracic vertebra, where the artery of Adamkiewicz is presumed to arise. He underwent left thoracotomy to remove t... | ['Evoked Potentials, Motor', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Mediastinal Neoplasms', 'Monitoring, Intraoperative', 'Multimodal Imaging', 'Tomography, X-Ray Computed', 'Young Adult'] | 28,790,251 | [['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.588.894.479', 'C08.846.187.580'], ['E01.370.520.510', 'E04.510'], ['E01.370.350.567'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.8... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Internal sclerostomy with the Er:YAG laser using a gradient-index (GRIN) endoscope. | BACKGROUND AND OBJECTIVE: To show that sclerostomy, a glaucoma filtering surgery, can be performed using an Er:YAG laser. Scarring at the filtering site, a recurrent problem, may be reduced through proper positioning of the sclerostomy by using an intraocular endoscope.MATERIALS AND METHODS: Ab interno full-thickness s... | ['Endoscopy', 'Eye Banks', 'Humans', 'Laser Therapy', 'Sclera', 'Sclerostomy'] | 12,027,101 | [['E01.370.388.250', 'E04.502.250'], ['N02.278.065.900.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['A09.371.784'], ['E04.540.450.600', 'E04.579.895']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anti-inflammatory Dimeric 2-(2-Phenylethyl)chromones from the Resinous Wood of Aquilaria sinensis. | Sixteen new 2-(2-phenylethyl)chromone dimers, including four pairs of enantiomers (1a/1b, 3a/3b, 6a/6b, and 8a/8b), along with eight optically pure analogues (2, 4, 5, 7, and 9-12) were isolated from the resinous wood of Aquilaria sinensis. Their structures were determined by extensive spectroscopic analysis (1D and 2D... | ['Animals', 'Anti-Inflammatory Agents', 'Cell Line', 'Cholinesterase Inhibitors', 'Flavonoids', 'Lipopolysaccharides', 'Magnetic Resonance Spectroscopy', 'Mice', 'Nitric Oxide', 'RAW 264.7 Cells', 'Resins, Plant', 'Thymelaeaceae', 'Wood'] | 29,227,647 | [['B01.050'], ['D27.505.954.158'], ['A11.251.210'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['E05.196.867.519'], ['B01.050.150.900.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The Belgrade childhood diabetes study - comparison of children with type 1 diabetes with their siblings. | A case-control study was conducted in Belgrade (about 320,000 inhabitants 0-16 years old) during the period 1994-97, comprising 68 diabetic children (cases) and 68 controls chosen from the siblings of the cases. Analysis using multivariable logistic regression analysis indicated the following independent risk factors f... | ['Adolescent', 'Age Distribution', 'Birth Order', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Communicable Diseases', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Infant', 'Learning Disabilities', 'Male', 'Models, Statistical', 'Risk Factors', 'Sex Distribution', 'Siblings', 'Stress, Psychological', 'Yug... | 16,629,698 | [['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['F01.829.263.132', 'I01.240.361.160', 'N01.224.361.160', 'N06.850.505.400.400.160'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C01.221', 'C23.550.291.531'], ['C18.452.39... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Distribution of transferrin and transferrin receptors in the rabbit placenta. | The quantity and distribution of transferrin and transferrin-binding sites in the placenta were investigated in rabbits on the 28th-29th days of pregnancy. The animals were injected intravenously with a mixture of 59Fe-125I-labelled rabbit diferric transferrin and 131I-labelled rabbit albumin. The binding of transferri... | ['Animals', 'Autoradiography', 'Female', 'Iron', 'Placenta', 'Pregnancy', 'Rabbits', 'Receptors, Cell Surface', 'Receptors, Transferrin', 'Transferrin'] | 6,310,669 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['A16.710'], ['G08.686.784.769'], ['B01.050.150.900.649.313.968.700'], ['D12.776.543.750'], ['D12.776.157.905.500', 'D12.776.543.750.800'], ['D12.776.124.050.800', 'D12.776.124.790.223.839... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A 100-year perspective on gastrointestinal motility. | This contribution to the centennial commemorative issue of the American Journal of Physiology: Gastrointestinal and Liver Physiology identifies some of the important studies of spontaneous electrical and motor activity in the gastrointestinal tract published in the Journal between 1898 and 1996. Emphasis is given to th... | ['Animals', 'Gastrointestinal Motility', 'History, 19th Century', 'History, 20th Century', 'Periodicals as Topic', 'Peristalsis', 'Physiology'] | 9,565,541 | [['B01.050'], ['G10.261.360'], ['K01.400.504.937'], ['K01.400.504.968'], ['L01.178.682.829.678'], ['G10.261.360.596'], ['H01.158.782']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Phospholipases. III. Effects of ionic surfactants on the phospholipase-catalyzed hydrolysis of unsonicated egg lecithin liposomes. | Apparent values of Km and Vmax have been measured for catalysis of hydrolysis of unsonicated egg lecithin liposomes, activated through addition of 0.4 M n-hexanol, by phospholipases A2 from bee and snake venoms and by phospholipase C from Clostridium welchii as a function of the concentration of three surfactants: hexa... | ['Amines', 'Cetrimonium Compounds', 'Hexanols', 'Hydrogen-Ion Concentration', 'Kinetics', 'Liposomes', 'Organophosphorus Compounds', 'Phosphatidylcholines', 'Phospholipases', 'Surface-Active Agents'] | 506 | [['D02.092'], ['D02.092.877.883.111', 'D02.675.276.190'], ['D02.033.415.510', 'D10.289.510'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D02.705'], ['D10.570.755.375.760.400.800'], ['D08.811.277.352.100.680', 'D08.811.277.352.640.700'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
HLA-DQA1 allele and suballele typing using noncoding sequence polymorphisms. Application to 4AOHW cell panel typing. | HLA-DQA1 typing of the 4AOHW cell panel is presented using a novel strategy that exploits both intron and exon polymorphisms. Intron sequences adjacent to the variable HLA-DQA1 second exon exhibit stable polymorphisms that are specific for locus alleles and certain suballelic DR/DQ haplotypes. A PCR-RFLP method has bee... | ['Alleles', 'Base Sequence', 'Cell Line, Transformed', 'Deoxyribonucleases, Type II Site-Specific', 'Exons', 'HLA-DQ Antigens', 'HLA-DQ alpha-Chains', 'HLA-DR Antigens', 'Haplotypes', 'Histocompatibility Testing', 'Humans', 'Introns', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fr... | 7,905,870 | [['G05.360.340.024.340.030'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.172'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['G05.360.340.024.340.137.232'], ['D12.776.395.550.509.400.430', 'D12.776.543.550.440.400.430', 'D23.050.301.500.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Characterization of the adaptive response to the action of gamma-rays, induced by low doses of 14C in Chinese hamster fibroblasts]. | It has been studied the correlation of the mitotic activity of the chromosome aberrations and apoptosis, in the V-79 cells pre-exposure to an adapting dose of ionizing radiation from 14C-thymidine prior to an acute challenge dose of gamma-rays. In spite of that the incubation of the cells with isotope increased of the ... | ['Adaptation, Physiological', 'Anaphase', 'Animals', 'Carbon Radioisotopes', 'Cell Line', 'Chromosome Aberrations', 'Cricetinae', 'Cricetulus', 'Fibroblasts', 'Gamma Rays', 'Metaphase', 'Mitosis'] | 9,876,490 | [['G07.025', 'G16.012.500'], ['G04.144.220.220.687.222', 'G04.144.220.220.781.050', 'G05.113.220.687.250', 'G05.113.220.781.050'], ['B01.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.9... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proton-Induced Conformational and Hydration Dynamics in the Influenza A M2 Channel. | The influenza A M2 protein is an acid-activated proton channel responsible for acidification of the inside of the virus, a critical step in the viral life cycle. This channel has four central histidine residues that form an acid-activated gate, binding protons from the outside until an activated state allows proton tra... | ['Histidine', 'Humans', 'Hydrogen Bonding', 'Hydrogen-Ion Concentration', 'Molecular Dynamics Simulation', 'Protein Conformation', 'Protons', 'Viral Matrix Proteins', 'Water'] | 31,264,413 | [['D12.125.072.329', 'D12.125.142.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['G02.300'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D12.776.964.970.880.940'], ['D01... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nucleolar introns from Physarum flavicomum contain insertion elements that may explain how mobile group I introns gained their open reading frames. | Comparison of two group I intron sequences in the nucleolar genome of the myxomycete Physarum flavicomum to their homologs in the closely related Physarum polycephalum revealed insertion-like elements. One of the insertion-like elements consists of two repetitive sequence motifs of 11 and 101 bp in five and three copie... | ['Animals', 'Base Sequence', 'Cell Nucleolus', 'Cloning, Molecular', 'DNA Transposable Elements', 'DNA, Fungal', 'DNA, Ribosomal', 'Introns', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Open Reading Frames', 'Physarum', 'RNA, Fungal', 'RNA, Ribosomal', 'Repetitive Sequences, Nucleic Acid', 'Sequence Alignm... | 7,984,404 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.430.106.279.345.175'], ['E05.393.220'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D13.444.308.300'], ['D13.444.308.475'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Quality improvement and managed care as curriculum elements. | The authors describe a clinical course that incorporates practical experience in continuous quality improvement, case management, managed care, and healthcare systems analysis. Increasingly, nurses need to know and be able to use these concepts; therefore, they were added to the nursing curriculum. Although nursing stu... | ['Curriculum', 'Education, Nursing, Baccalaureate', 'Health Services Research', 'Humans', 'Managed Care Programs', 'Quality Assurance, Health Care'] | 8,336,854 | [['I02.158'], ['I02.358.462.316'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N04.761.700', 'N05.700']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2. | Methyl glyoxal (MG), a highly reactive dicarbonyl metabolite, causes a range of changes within the cell. It forms adducts with DNA and protein and contributes to the progression of several diseases as well as causing hepatic damage. In this study, we have used human hepatoma (HepG2) cells as a model to investigate the ... | ['3-Hydroxysteroid Dehydrogenases', 'Aldehyde Reductase', 'Aldo-Keto Reductase Family 1 Member C3', 'Cell Line, Tumor', 'Glyoxal', 'Hep G2 Cells', 'Humans', 'Hydroxyprostaglandin Dehydrogenases', 'NAD(P)H Dehydrogenase (Quinone)', 'NADP', 'NF-E2-Related Factor 2', 'RNA, Messenger', 'Up-Regulation'] | 25,451,587 | [['D08.811.682.047.436.350'], ['D08.811.682.047.150.700.156.500', 'D08.811.682.047.820.284.500'], ['D08.811.682.047.150.700.156.875', 'D08.811.682.047.436.375.140', 'D08.811.682.047.820.284.937', 'D08.811.682.047.820.375.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.047.644'], ['A11.251.860.180.432', 'A11.436.34... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patterns of VOC and BTEX concentration in ambient air around industrial sources in Daegu, Korea. | Patterns of VOC and BTEX (Benzene, Toluene, Ethylvenzene, and Xylene) distribution at industrial emission sources, proximal residential areas of industrial estates, and ambient air were studied in Daegu, Korea. Daytime and night-time sampling was done at 12 sites and 9 emission sources to provide samples for analyses, ... | ['Air Pollutants', 'Hydrocarbons, Aromatic', 'Industrial Waste', 'Korea', 'Volatile Organic Compounds'] | 19,085,600 | [['D27.888.284.101'], ['D02.455.426.559'], ['D20.944.420', 'N06.850.460.710.420'], ['Z01.252.474.557', 'Z01.586.407'], ['D02.974']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Microphthalmia with linear skin defects syndrome (MLS): a male with a mosaic paracentric inversion of Xp. | The microphthalmia with linear skin defects syndrome (MLS) is an X-linked dominant disorder with male lethality. In the majority of the patients reported, the MLS syndrome is caused by segmental monosomy of the Xp22.3 region. To date, five male patients with MLS and 46,XX karyotype ("XX males") have been described. Her... | ['Chromosome Inversion', 'Chromosomes, Human, X', 'Fatal Outcome', 'GTPase-Activating Proteins', 'Humans', 'In Situ Hybridization, Fluorescence', 'Infant', 'Karyotyping', 'Male', 'Microphthalmos', 'Mosaicism', 'Sex Chromosome Aberrations', 'Skin Abnormalities', 'Syndrome'] | 12,900,578 | [['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], [... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of early intervention services on duration of untreated psychosis: data from the National EDEN prospective cohort study. | OBJECTIVE: This study aimed to determine if the inception of Early Intervention Services (EISs) is followed by an improvement in the prompt treatment of people with first episode psychosis.METHOD: A prospective cohort study of referrals to new and established EISs was conducted at 1, 2, 3, and 4 years after inception o... | ['Adolescent', 'Adult', 'Early Medical Intervention', 'England', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Prospective Studies', 'Psychotic Disorders', 'Sensitivity and Specificity', 'Time-to-Treatment', 'Young Adult'] | 25,107,851 | [['M01.060.057'], ['M01.060.116'], ['N02.421.726.363'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['F03.700.67... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Porous M(II)/pyrimidine-4,6-dicarboxylato neutral frameworks: synthetic influence on the adsorption capacity and evaluation of CO2-adsorbent interactions. | The understanding of the factors that affect the real pore-network structure for a given bulk material due to different synthetic procedures is essential to develop the material with the best adsorption properties. In this work, we have deeply studied the influence of the crystallinity degree over the adsorption capaci... | ['Adsorption', 'Carbon Dioxide', 'Carboxylic Acids', 'Metals', 'Models, Molecular', 'Organometallic Compounds', 'Porosity', 'Pyrimidines'] | 24,403,128 | [['G01.030', 'G02.020'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D02.241'], ['D01.552'], ['E05.599.595'], ['D02.691'], ['G01.374.710'], ['D03.383.742']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Computational study on the reactions of H2O2 on TiO2 anatase (101) and rutile (110) surfaces. | This study investigates the adsorption and reactions of H(2)O(2) on TiO(2) anatase (101) and rutile (110) surfaces by first-principles calculations based on the density functional theory in conjunction with the projected augmented wave approach, using PW91, PBE, and revPBE functionals. Adsorption mechanisms of H(2)O(2)... | ['Adsorption', 'Hydrogen Peroxide', 'Quantum Theory', 'Surface Properties', 'Titanium'] | 21,387,334 | [['G01.030', 'G02.020'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['H01.671.579.800'], ['G02.860'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene cloning, heterologous overexpression and optimized refolding of the NAD-glutamate dehydrogenase from Haloferax mediterranei. | The NAD-dependent glutamate dehydrogenase (GDH) gene from the halophilic archaeon Haloferax mediterranei has been cloned. The analysis of the nucleotide sequence revealed an open reading frame of 1323 bp that encodes a NAD-GDH. The amino acid sequence displayed high homology with those from other sources, especially th... | ['Amino Acid Sequence', 'Archaeal Proteins', 'Cloning, Molecular', 'Gene Library', 'Glutamate Dehydrogenase', 'Haloferax mediterranei', 'Hydrogen-Ion Concentration', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Protein Folding', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Substrate Specificity... | 16,200,391 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.090'], ['E05.393.220'], ['G05.360.325'], ['D08.811.682.664.500.398'], ['B02.200.400.400.440.500'], ['G02.300'], ['L01.453.245.667'], ['E05.393.620.500'], ['G01.154.651', 'G02.111.688'], ['D12.776.828'], ['G02.111.810.200', 'G05.810.200'], ['G02.111.835'], ['G01.906... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Synergistic effects of celecoxib and bupropion in a model of chronic inflammation-related depression in mice. | This study was aimed to characterize the depression-like behaviour in the classical model of chronic inflammation induced by Complete Freund's Adjuvant (CFA). Male Swiss mice received an intraplantar (i.pl.) injection of CFA (50 µl/paw) or vehicle. Behavioural and inflammatory responses were measured at different time-... | ['Analgesics', 'Animals', 'Anti-Inflammatory Agents', 'Antidepressive Agents', 'Behavior, Animal', 'Brain-Derived Neurotrophic Factor', 'Bupropion', 'Celecoxib', 'Cerebral Cortex', 'Cyclooxygenase 2', 'Depression', 'Dipyrone', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Edema', "Fre... | 24,086,771 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.954.158'], ['D27.505.954.427.700.122'], ['F01.145.113'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['D02.522.818.110'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['A08.186... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation and characterisation of alendronate-loaded chitosan microparticles obtained through the spray drying technique. | Microparticles of chitosan (CHT) containing alendronate sodium (AL) were prepared in four drug:polymer ratios (1:1, 1:2, 1:4, 1:6) using the spray drying technique. The efficiency of the method was evaluated by determining production yield (about 70 %) and microencapsulation efficiency, which was almost 100 % in the ca... | ['Alendronate', 'Biological Availability', 'Calorimetry, Differential Scanning', 'Chitosan', 'Drug Carriers', 'Humans', 'Hydrogen-Ion Concentration', 'Microscopy, Electron, Scanning', 'Microspheres', 'Particle Size', 'Spectrophotometry, Infrared', 'Surface Properties', 'Thermogravimetry'] | 19,275,718 | [['D02.705.429.500.100'], ['G03.787.151', 'G07.690.725.129'], ['E05.196.131.310', 'E05.196.370.310'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D26.255.260', 'E02.319.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E07.565'], ['G02.712'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does the Janani Suraksha Yojana cash transfer programme to promote facility births in India ensure skilled birth attendance? A qualitative study of intrapartum care in Madhya Pradesh. | BACKGROUND: Access to facility delivery in India has significantly increased with the Janani Suraksha Yojana (JSY) cash transfer programme to promote facility births. However, a decline in maternal mortality has only followed secular trends as seen from the beginning of the decade well before the programme began. We, t... | ['Adult', 'Attitude of Health Personnel', 'Environment', 'Female', 'Health Personnel', 'Health Services Accessibility', 'Humans', 'India', 'Interviews as Topic', 'Maternal Health Services', 'Maternal Mortality', 'Medical Assistance', 'Parturition', 'Patient Acceptance of Health Care', 'Program Evaluation', 'Qualitative... | 26,160,769 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['G16.500.275', 'N06.230'], ['M01.526.485', 'N02.360'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N02.421.143.620', 'N... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide. | PURPOSE: This phase II study evaluated the efficacy and safety of a 7-day on/7-day off regimen of temozolomide before radiotherapy (RT) in patients with inoperable newly diagnosed glioblastoma.PATIENTS AND METHODS: Patients received temozolomide (150 mg/m2/d on days 1 to 7 and days 15 to 21 every 28 days; 7 days on/7 d... | ['Adolescent', 'Adult', 'Aged', 'Biomarkers, Tumor', 'Brain Neoplasms', 'Chemotherapy, Adjuvant', 'Dacarbazine', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Follow-Up Studies', 'Glioblastoma', 'Humans', 'Magnetic Resonance Imaging', 'Maximum Tolerated Dose', 'Middle Aged', 'Neoplasm Staging', '... | 17,442,989 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E02.186.170', 'E02.319.170'], ['D02.925.200', 'D03.383.129.308.240'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.35... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Food irradiation: the process and implications for dietitians. | Despite the limited use of irradiation for food preservation in the United States to date, the process provides an alternative to the use of some chemical pesticides and sprout inhibitors. The formation of random and varied radiolytic products (RPs) in foods that have been irradiated is the focus of criticism of the pr... | ['Chemical Phenomena', 'Chemistry', 'Dietary Carbohydrates', 'Dietary Fats', 'Dietary Proteins', 'Dietetics', 'Food Irradiation', 'Vitamins'] | 3,385,107 | [['G02'], ['H01.181'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['H02.533.290'], ['J01.576.423.850.700.700.500'], ['D27.505.696.494.600', 'G07.203.300.681.500.600', 'J02.500.681.500.600']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Conformational restrictions in ligand binding to the human intestinal di-/tripeptide transporter: implications for design of hPEPT1 targeted prodrugs. | The aim of the present study was to develop a computational method aiding the design of dipeptidomimetic pro-moieties targeting the human intestinal di-/tripeptide transporter hPEPT1. First, the conformation in which substrates bind to hPEPT1 (the bioactive conformation) was identified by conformational analysis and 2D... | ['Amination', 'Dipeptides', 'Drug Design', 'Humans', 'Intestines', 'Ligands', 'Molecular Structure', 'Peptide Transporter 1', 'Prodrugs', 'Symporters', 'Water', 'beta-Lactams'] | 15,727,852 | [['G02.111.053', 'G02.607.110', 'G03.068'], ['D12.644.456.345'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['D27.720.470.480'], ['G02.111.570', 'G02.466'], ['D12.776.157.530.450.625.202', 'D12.776.157.530.937.613', 'D12.776.543.5... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Normalize the response of EPID in pursuit of linear accelerator dosimetry standardization. | Normalize the response of electronic portal imaging device (EPID) is the first step toward an EPID-based standardization of Linear Accelerator (linac) dosimetry quality assurance. In this study, we described an approach to generate two-dimensional (2D) pixel sensitivity maps (PSM) for EPIDs response normalization utili... | ['Algorithms', 'Electrical Equipment and Supplies', 'Humans', 'Particle Accelerators', 'Phantoms, Imaging', 'Photons', 'Quality Assurance, Health Care', 'Quality Control', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Intensity-Modulated'] | 29,125,224 | [['G17.035', 'L01.224.050'], ['E07.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.710.680'], ['E07.671'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['N04.761.700', 'N05.700'], ['J01.897.608'], ['E02.815.639'], ['E02.950.825', 'L01.313.500... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
A 2-year follow-up of root coverage using sub-pedicle acellular dermal matrix allografts and subepithelial connective tissue autografts. | BACKGROUND: Coverage of roots exposed by gingival recession is one of the main objectives of periodontal reconstructive surgery. A large variety of mucogingival grafting procedures are available. However, the long-term effectiveness of this procedure is still not clear. This study compared the effectiveness of sub-pedi... | ['Adult', 'Connective Tissue', 'Female', 'Follow-Up Studies', 'Gingival Recession', 'Humans', 'Male', 'Mouth Mucosa', 'Retrospective Studies', 'Skin Transplantation', 'Skin, Artificial'] | 16,101,365 | [['M01.060.116'], ['A10.165'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C07.465.714.258.447', 'C07.465.714.354.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.615.550.599', 'A14.549.512'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and anxiolytic activity of N-substituted cyclic imides (1R*,2S*,3R*,4S*)-N-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,3- bicyclo[2.2.1]heptanedicarboximide (tandospirone) and related compounds. | A series of cyclic imides bearing a omega-(4-aryl and 4-heteroaryl-1-piperazinyl)alkyl moieties was synthesized and tested in vivo for anxiolytic activity. The in vitro binding affinities of these compounds were also examined for 5-HT1A receptor sites. Structure-activity relationships within these series are discussed.... | ['Animals', 'Anti-Anxiety Agents', 'Imides', 'Isoindoles', 'Piperazines', 'Pyrimidines', 'Rats'] | 1,687,114 | [['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D02.478'], ['D03.633.100.513'], ['D03.383.606'], ['D03.383.742'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of cutaneous findings in Spanish neonates and relationships to obstetric and parental factors. | Two hundred forty-seven healthy newborns were investigated in a prospective cohort descriptive study. Information on phenotype and obstetric and parental history was collected. A positive association was found between erythema toxicum neonatorum and season of birth (spring and summer), whereas parental history of any s... | ['Adult', 'Delivery, Obstetric', 'Dermatitis, Atopic', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Prevalence', 'Prospective Studies', 'Seasons', 'Skin Diseases', 'Spain'] | 21,995,510 | [['M01.060.116'], ['E04.520.252'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evolution of low-copy number and major satellite DNA sequences coexisting in two Pimelia species-groups (Coleoptera). | Satellite DNA sequence evolution has been studied in several insect species from the genus Pimelia (Tenebrionidae, Coleoptera). Low-copy number homologs of the previously characterized major satellite DNA from P. monticola (PMON) have been cloned and sequenced from six congeneric species belonging to two species groups... | ['Animals', 'Base Sequence', 'Coleoptera', 'DNA', 'DNA, Satellite', 'Evolution, Molecular', 'Gene Dosage', 'Genetic Variation', 'Molecular Sequence Data', 'Phylogeny', 'Repetitive Sequences, Nucleic Acid', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Sequence Homology, Nucleic Acid', 'Species Specificity'] | 12,909,343 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.131.617.720.500.500.375'], ['D13.444.308'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['G05.045.250', 'G16.075.250'], ['G05.380.350'], ['G05.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reduction in potassium concentration of stored red blood cell units using a resin filter. | BACKGROUND: Hyperkalemia is a serious complication of rapid and massive blood transfusion due to high plasma potassium (K) in stored red blood cell (RBC) units. A potassium adsorption filter (PAF) was developed in Japan to remove K by exchanging with sodium (Na). We performed an in vitro evaluation of its efficacy and ... | ['Erythrocytes', 'Filtration', 'Humans', 'Potassium'] | 20,561,298 | [['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Our experience with the diagnosis and treatment of biliary pancreatitis]. | The diagnostic and therapeutic problems faced during treatment of thirty-nine patients presenting biliopancreatitis (BP) are discussed. BP diagnosis is made on the ground of clinical picture, laboratory indicators, abdominal ultrasonography, intraoperative cholangio-pancreatography and cholangioscopy. Patients with cho... | ['Acute Disease', 'Adult', 'Cholecystectomy', 'Cholelithiasis', 'Drainage', 'Female', 'Humans', 'Male', 'Middle Aged', 'Necrosis', 'Pancreas', 'Pancreatectomy', 'Pancreatitis'] | 7,877,262 | [['C23.550.291.125'], ['M01.060.116'], ['E04.210.120.172'], ['C06.130.409'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.717'], ['A03.734'], ['E04.210.752'], ['C06.689.750']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The results of using Virolex (acyclovir) in patients with herpetic keratitis]. | Virolex (acyclovir) used as 3% ointment in 50 patients (50 eyes) with herpetic keratitis was found highly effective in dendritic keratitis and sufficiently effective in keratoiridocyclitis with ulcerations (megaherpetic keratitis), providing cure in 92 and 75%, of cases, respectively. The drug is ineffective in the tre... | ['Acyclovir', 'Adolescent', 'Adult', 'Aged', 'Anti-Infective Agents, Local', 'Drug Evaluation', 'Drug Therapy, Combination', 'Female', 'Humans', 'Idoxuridine', 'Keratitis, Herpetic', 'Male', 'Middle Aged', 'Mydriatics', 'Ointments'] | 8,310,597 | [['D03.633.100.759.758.399.454.250'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.187'], ['E05.290.625', 'E05.337.425'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.742.680.852.300.400', 'D13.570.230.430.609', 'D13.570.685.852.300.400'], ['C01.375.725.465', '... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[APPLICATION OF FREE BILOBED MEDIAL SURAL ARTERY PERFORATOR FLAP FOR REPAIRING PENETRATING WOUND OF FOOT]. | OBJECTIVE: To explore the effectiveness of the free bilobed medial sural artery perforator (BMSAP) flap to repair penetrating wound of the foot.METHODS: Between April 2012 and October 2014, 7 cases of foot penetrating wounds were treated with the BMSAP flap. There were 5 males and 2 females, aged from 21 to 43 years (m... | ['Adult', 'Drainage', 'Female', 'Femoral Artery', 'Foot', 'Humans', 'Male', 'Necrosis', 'Perforator Flap', 'Reconstructive Surgical Procedures', 'Sensation', 'Skin', 'Skin Transplantation', 'Soft Tissue Injuries', 'Sural Nerve', 'Treatment Outcome', 'Wound Healing', 'Wounds, Penetrating'] | 27,044,222 | [['M01.060.116'], ['E02.309', 'E04.237'], ['A07.015.114.351'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.717'], ['A10.850.710.750', 'E07.862.710.750'], ['E04.680'], ['F02.830.816', 'G11.561.790'], ['A17.815'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['C26.808... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of survivin reduces HIF-1á, TGF-â1 and TFE3 in salivary adenoid cystic carcinoma. | In the present study, we explored the expression and correlation of survivin with HIF-1á, TGF-â1 and TFE3 in adenoid cystic carcinoma (AdCC). The expression of survivin, HIF-1á, TGF-â1 and TFE3 was assessed by immunohistochemical staining of a tissue microarray containing tissue samples of normal salivary gland (NSG), ... | ['Basic Helix-Loop-Helix Leucine Zipper Transcription Factors', 'Carcinoma, Adenoid Cystic', 'Case-Control Studies', 'Cell Line, Tumor', 'Cluster Analysis', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Imidazoles', 'Immunohistochemistry', 'Inhibito... | 25,485,635 | [['D12.776.260.103.500', 'D12.776.260.108.092', 'D12.776.930.125.500', 'D12.776.930.127.092'], ['C04.557.470.200.025.220'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G05.297'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Physico-chemical and Histomorphometric Evaluation of Zinc-containing Hydroxyapatite in Rabbits Calvaria. | The aim of this study was to characterize the physico-chemical properties and bone repair after implantation of zinc-containing nanostructured porous hydroxyapatite scaffold (nZnHA) in rabbits' calvaria. nZnHA powder containing 2% wt/wt zinc and stoichiometric nanostructured porous hydroxyapatite (nHA - control group) ... | ['Animals', 'Biocompatible Materials', 'Durapatite', 'Fluorescence', 'Microscopy, Electron, Scanning', 'Rabbits', 'Skull', 'Spectrophotometry, Infrared', 'X-Ray Diffraction', 'Zinc'] | 27,982,185 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.050.150.900... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pulmonary tumor microembolism. | Pulmonary tumor embolism is an often missed antemortem diagnosis in patients with cancer and respiratory failure. Although rare, this complication is an important cause of additional morbidity. Referred for radionuclide pulmonary perfusion and ventilation scintigraphy, a typical pattern of multiple subsegmental periphe... | ['Adenocarcinoma', 'Autopsy', 'Diagnosis, Differential', 'Dyspnea', 'Fatal Outcome', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Pulmonary Embolism', 'Radiography, Thoracic', 'Radionuclide Imaging'] | 9,650,217 | [['C04.557.470.200.025'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E01.171'], ['C08.618.326', 'C23.888.852.371'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.38... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Analysis of the Gamete-Fusion Genes in the Haploid-inducing ZMS-P Maize Line]. | This article is devoted to the study of the double fertilization mechanism in plants, in particular of
the maize gamete membrane fusion genes. We detected and analyzed for the first time gamete-fusion genes
in the maize genome. Using the BLAST program, we searched for the hap2 gene (generative cell specific 1
(gcs1)) h... | ['Arabidopsis', 'Carrier Proteins', 'Germ Cells, Plant', 'Haploidy', 'Plant Proteins', 'Zea mays'] | 30,277,363 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.157'], ['A11.497.248', 'A18.024.249.500.249'], ['G05.700.456'], ['D12.776.765'], ['B01.650.940.800.575.912.250.822.966']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Method of determining disease severity in women with pelvic varicose veins]. | BACKGROUND: Using assessment scales in clinical and research practice is one of fundamental reference methods of evaluation in human pathological states. Pelvic vein varicosity is an independent nosological entity within the framework of chronic vein diseases. Currently, the clinical methods of assessment in the aspect... | ['Female', 'Humans', 'Pelvis', 'Prospective Studies', 'Severity of Illness Index', 'Treatment Outcome', 'Varicose Veins', 'Veins', 'Venous Insufficiency'] | 31,503,250 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.600'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
House-dust mite nasal provocation: a diagnostic tool in perennial rhinitis. | BACKGROUND: In perennial allergic rhinitis (PAR), the skin-prick test (SPT) is a good diagnostic tool to identify the specific allergens. A nasal provocation test (NPT) is used to identify allergens and to confirm the diagnosis. The aim of this study was to determine the optimal cutoff values of symptom and peak nasal ... | ['Adolescent', 'Animals', 'Antigens, Dermatophagoides', 'Feasibility Studies', 'Female', 'Humans', 'Inspiratory Capacity', 'Male', 'Middle Aged', 'Nasal Provocation Tests', 'Predictive Value of Tests', 'Pyroglyphidae', 'Reference Standards', 'Respiratory Function Tests', 'Rhinitis, Allergic, Perennial', 'Sensitivity an... | 20,338,112 | [['M01.060.057'], ['B01.050'], ['D23.050.181'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485.750.900.350', 'G09.772.850.970.500'], ['M01.060.116.630'], ['E01.370.386.550'], ['E05.318.370.800.650', 'N05.715.360.32... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Malpractice in diagnosis and treatment of craniocerebral injuries in cases reviewed by the Forensic Medicine Department, Medical University of ??d?. | BACKGROUND AND PURPOSE: The aim of the study was to determine the most frequent errors in medical treatment of craniocerebral injuries, based on materials reviewed by the Forensic Medicine Department, Medical University of ??d?, Poland.MATERIAL AND METHODS: Legal opinions in the area of craniocerebral injuries, elabora... | ['Academic Medical Centers', 'Craniocerebral Trauma', 'Diagnosis, Differential', 'Disability Evaluation', 'Disease-Free Survival', 'Female', 'Forensic Medicine', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Malpractice', 'Medical Errors', 'Poland', 'Professional Misconduct', 'Retrospective Studies'] | 17,874,341 | [['N02.278.020'], ['C10.900.300', 'C26.915.300'], ['E01.171'], ['E01.370.400'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
HIV-1 drug-resistant mutations and related risk factors among HIV-1-positive individuals experiencing treatment failure in Hebei Province, China. | BACKGROUND: To understand HIV-1 drug resistance in 11 prefectures of Hebei Province, China, we implemented a cross-sectional HIV-1 molecular epidemiological survey.METHODS: Blood samples were collected from 122 newly diagnosed drug-na?ve HIV-1-positive individuals and 229 antiretroviral therapy (ART)-failure individual... | ['Adolescent', 'Adult', 'Aged', 'Anti-HIV Agents', 'Child', 'China', 'Cross-Sectional Studies', 'Drug Resistance, Viral', 'Female', 'HIV Infections', 'HIV-1', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Prevalence', 'Risk Factors', 'Treatment Failure', 'Viral Load', 'Young Adult'] | 28,114,955 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388.077.088'], ['M01.060.406'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Dynamic Reorganization of Functional Connectivity Reveals Abnormal Temporal Efficiency in Schizophrenia. | Emerging evidence suggests that schizophrenia is associated with brain dysconnectivity. Nonetheless, the implicit assumption of stationary functional connectivity (FC) adopted in most previous resting-state functional magnetic resonance imaging (fMRI) studies raises an open question of schizophrenia-related aberrations... | ['Adolescent', 'Adult', 'Aged', 'Atlases as Topic', 'Brain', 'Connectome', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Nerve Net', 'Schizophrenia', 'Time Factors', 'Young Adult'] | 29,878,254 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['L01.178.682.192.836.147'], ['A08.186.211'], ['E01.370.350.578.875.500.249', 'E01.370.376.537.625.500.249', 'E05.629.875.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A08.511'], ['F03.700.750'], ['G01.... | ['Named Groups [M]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Acceptance of transsexualism among university students from L?d?]. | UNLABELLED: Transsexualism is one of the gender identity disorders where psychological sex is opposed to anatomical sex. This disorder leads to a discrepancy between the preferred social gender and the biological sex.AIM: The aim of this research is to compare knowledge and attitude toward transsexualism in student's o... | ['Adult', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interpersonal Relations', 'Male', 'Peer Group', 'Poland', 'Social Environment', 'Social Perception', 'Stereotyping', 'Students', 'Surveys and Questionnaires', 'Transsexualism', 'Universities'] | 18,567,410 | [['M01.060.116'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.829.316.483'], ['Z01.542.248.679'], ['I01.880.853.500'], ['F02.463.593.752'], ['F01.100.920', 'F01.145.813.854'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
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