Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Effect of nickel deficiency on biochemical variables in serum, liver, heart and kidneys of goats. | Nickel deficiency was induced in 2- to 4-year-old goats by feeding 0.1 mg Ni/kg dry matter with a semisynthetic diet. The control group consumed 5.0 mg Ni/kg d.m. Activity of several enzymes (SDH, LDH, HBDH, AST, ALT, ALD, CK, CHE) was determined in the serum, liver, heart and kidneys. Serum urea-N level was also measu... | ['Animals', 'Female', 'Goat Diseases', 'Goats', 'Kidney', 'Liver', 'Myocardium', 'Nickel'] | 1,785,440 | [['B01.050'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['A05.810.453'], ['A03.620'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Life-long screening of patients with intermediate-thickness cutaneous melanoma for asymptomatic pulmonary recurrences: a cost-effectiveness analysis. | BACKGROUND: Costs and potential benefits of an intensive chest X-ray (CXR) screening program to detect asymptomatic pulmonary metastases in patients with intermediate-thickness, local, cutaneous melanoma were assessed.METHODS: Cost-effectiveness analysis from a societal perspective was performed using data on recurrenc... | ['Aged', 'Cost-Benefit Analysis', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Mass Chest X-Ray', 'Melanoma', 'Middle Aged', 'Population Surveillance', 'Quality-Adjusted Life Years', 'Sensitivity and Specificity', 'Skin Neoplasms'] | 9,305,705 | [['M01.060.116.100'], ['N03.219.151.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E01.370.350.700.730.500', 'E01.370.386.500', 'E01.370.500.500', 'E05.318.308.980.438.580.510', 'N02.421.726.233.443.443', 'N05.715.360.300.800.438.500.500', 'N06.850.520.3... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification and characterization of non-cellulose-producing mutants of Gluconacetobacter hansenii generated by Tn5 transposon mutagenesis. | The acs operon of Gluconacetobacter is thought to encode AcsA, AcsB, AcsC, and AcsD proteins that constitute the cellulose synthase complex, required for the synthesis and secretion of crystalline cellulose microfibrils. A few other genes have been shown to be involved in this process, but their precise role is unclear... | ['Biosynthetic Pathways', 'Cellulose', 'DNA Transposable Elements', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Gene Knockout Techniques', 'Genetic Complementation Test', 'Gluconacetobacter', 'Immunoblotting', 'Mutagenesis, Insertional', 'Operon', 'Promoter Regions, Genetic', 'Real-Time Polym... | 24,013,627 | [['G02.111.098', 'G03.493.100'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['E05.393.332'], ['G05.308.300'], ['E05.393.335.750'], ['E05.393.281.526'], ['B03.440.400.4... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Partial trisomy 12q. | A partial trisomy 12q243 leads to qter resulting from a maternal balanced translocation, 46,XX,t(9;12)(p243;q243) was detected in a male newborn with multiple congenital abnormalities. The maternal grandmother was also a carrier of the 9;12 translocation. Our patient exhibited a number of clinica features similar to tw... | ['Abnormalities, Multiple', 'Chromosome Aberrations', 'Chromosome Disorders', 'Chromosomes, Human, 6-12 and X', 'Female', 'Humans', 'Pedigree', 'Translocation, Genetic', 'Trisomy'] | 7,241,532 | [['C16.131.077'], ['C23.550.210', 'G05.365.590.175'], ['C16.131.260', 'C16.320.180'], ['A11.284.187.520.300.325', 'G05.360.162.520.300.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.673'], ['C23.550.210.870', 'G05.365.590.175.870', 'G05.558.860'], ['C23.550.210.050.750', 'C23.550.210.182.500', 'G05.3... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alleviation of temperature-sensitive secretion defect of Pseudomonas fluorescens ATP-binding cassette (ABC) transporter, TliDEF, by a change of single amino acid in the ABC protein, TliD. | An ABC transporter, TliDEF, from Pseudomonas fluorescens SIK W1, mediates the secretion of its cognate lipase, TliA, in a temperature-dependent secretion manner; the TliDEF-mediated secretion of TliA was impossible at the temperatures over 33°C. To isolate a mutant TliDEF capable of secreting TliA at 35°C, the mutagene... | ['ATP-Binding Cassette Transporters', 'Amino Acids', 'Bacterial Proteins', 'Culture Media', 'Escherichia coli', 'Lipase', 'Point Mutation', 'Pseudomonas fluorescens', 'Temperature'] | 27,033,673 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D12.125'], ['D12.776.097'], ['D27.720.470.305', 'E07.206'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.352.100.400'], ['G05.365.590.675'], ['B03.440.400.425.625.625.325', 'B03.660.250.580.590.210'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ultrasound effect used as external stimulus for viscosity change of aqueous carrageenans. | Ultrasound (US) serves as a stimulus to change shear viscosity of aqueous polysaccharides of é-carrageenan, ê-carrageenan and, agar. The US effect was compared in their aqueous solutions at 60 °C for the US frequency of 23, 45, and 83 kHz. Under the US condition with 50 W at 45 kHz, the shear viscosity of each aqueous ... | ['Agar', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Carrageenan', 'Molecular Sequence Data', 'Sonication', 'Viscosity', 'Water'] | 23,395,152 | [['D09.698.360.041'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D09.698.152'], ['L01.453.245.667'], ['E05.848'], ['G02.930'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interaction of E. coli RNA polymerase with promotors of coliphage T5: the rates of complex formation and decay and their correlation with in vitro and in vivo transcriptional activity. | The genome of virulent coliphage T5 contains about 30 sites which form stable complexes with E. coli RNA polymerase. Some of these sites bind RNA polymerase with high rates, others form extremely stable complexes as compared with promotors of other E. coli systems. The transcriptional activity of these promotors in viv... | ['Binding Sites', 'Coliphages', 'DNA, Viral', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Genes, Viral', 'RNA, Bacterial', 'Transcription, Genetic'] | 340,927 | [['G02.111.570.120'], ['B04.123.205'], ['D13.444.308.568'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['D13.444.735.473'], ['G02.111.873', 'G05.297.700']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the mechanism of transfer of cholesterol between human erythrocytes and plasma. | The kinetics of transfer of [3H]cholesterol between human erythrocytes and plasma at 37 degrees C in physiological buffer had these features. 1) Cholesterol transfer was strikingly similar in both directions. 2) Transfer progressed to isotopic equilibrium in a monotonic, apparently first order fashion, except for a min... | ['Biological Transport', 'Cholesterol', 'Erythrocytes', 'Humans', 'Kinetics', 'Liposomes', 'Plasma', 'Tritium'] | 6,853,509 | [['G03.143'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['A12.207.152.693... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sialoglycoderivatives of bovine submandibular gland identified in situ by histochemical techniques combined with lectins. | We employed sialidase procedures followed by lectin stainings combined with oxidizing and deacetylating agents to visualize the distribution and sequentiate sialoglycoconjugates in the bovine submandibular gland. In particular we evidenced in acinar and ductal cells the dishomogeneous presence of sialic acids acetylate... | ['Animals', 'Cattle', 'Glycoconjugates', 'Histocytochemistry', 'Lectins', 'Neuraminidase', 'Sialic Acids', 'Submandibular Gland'] | 1,500,295 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D09.400'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['D12.776.503'], ['D08.811.277.450.692'], ['D02.241.081.844.562.668', 'D02.241.511.902.562.668', 'D09.067... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Interstitial nephritis associated with glomerulonephritis in a patient with Hashimoto's disease and idiopathic portal hypertension. | A middle-aged women with hypothyroidism, idiopathic portal hypertension and nephrotic syndrome is presented. This unusual clinical appearance could not be explained as SLE by serological examinations. Pathohistological examinations showed "Banti's liver", Hashimoto's thyroiditis and diffuse proliferative glomerulonephr... | ['Female', 'Glomerulonephritis', 'Humans', 'Hypertension, Portal', 'Immunoglobulin A', 'Kidney Glomerulus', 'Microscopy, Electron', 'Middle Aged', 'Nephritis, Interstitial', 'Thyroiditis, Autoimmune'] | 1,504,428 | [['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of plyometric training on swimming block start performance in adolescents. | This study aimed to identify the effect of plyometric training (PT), when added to habitual training (HT) regimes, on swim start performance. After the completion of a baseline competitive swim start, 22 adolescent swimmers were randomly assigned to either a PT (n = 11, age: 13.1 +/- 1.4 yr, mass: 50.6 +/- 12.3 kg, sta... | ['Adolescent', 'Athletic Performance', 'Child', 'Exercise', 'Humans', 'Muscle Contraction', 'Muscle, Skeletal', 'Swimming'] | 19,855,343 | [['M01.060.057'], ['I03.450.642.845.054'], ['M01.060.406'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845.945.500']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The effect of unipolar aeroions on the capacity of mammalian organism. | Based on animal experiments authors established that the different polarity high-concentration aeroions have an effect on the vegetative centres of the Central Nervous System (CNS). Through vegetative centres they influence both electro- and neuro-physiological relations of the nervous system and by this means they mak... | ['Air Ionization', 'Amphetamine', 'Animals', 'Brain', 'Chlorpromazine', 'Electronystagmography', 'Eye Movements', 'Guinea Pigs', 'Ions', 'Male', 'Mice', 'Orientation', 'Vestibule, Labyrinth'] | 317,402 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The ultrastructure of the juxta-oral organ (author's transl)]. | The ultrastructure of the juxta-oral organ has been investigated in the goldhamster. Its morphology was comparable to that already described in other species. Located in the cheek or in its anatomical homologue, the juxta-oral organ consists of a string of epithelial cells surrounded by two distinct layers. The first o... | ['Animals', 'Cheek', 'Cricetinae', 'Epithelial Cells', 'Female', 'Male', 'Mesocricetus', 'Microscopy, Electron', 'Mouth', 'Nerve Fibers', 'Parotid Gland', 'Sense Organs'] | 7,469,412 | [['B01.050'], ['A01.456.505.173', 'A14.194'], ['B01.050.150.900.649.313.992.635.075.250'], ['A11.436'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['E01.370.350.515.402', 'E05.595.402'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['A08.675.542', 'A11.671.501'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of heterotrimeric Gá proteins in maize development and enhancement of agronomic traits. | Plant shoot systems derive from the shoot apical meristems (SAMs), pools of stems cells that are regulated by a feedback between the WUSCHEL (WUS) homeobox protein and CLAVATA (CLV) peptides and receptors. The maize heterotrimeric G protein á subunit COMPACT PLANT2 (CT2) functions with CLV receptors to regulate meriste... | ['Agriculture', 'GTP-Binding Protein alpha Subunits', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Plant', 'Gene Knockout Techniques', 'Genes, Plant', 'Meristem', 'Mutation', 'Phylogeny', 'Plant Leaves', 'Plant Proteins', 'Plants, Genetically Modified', 'Zea mays'] | 29,708,966 | [['J01.040'], ['D08.811.277.040.330.300.200.100', 'D12.644.360.360.100', 'D12.776.157.325.332.100', 'D12.776.476.375.100', 'D12.776.543.325.100'], ['G05.308.310'], ['G05.308.375'], ['E05.393.335.750'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['A18.024.875.875', 'A18.024.937.500', 'A18.400.500'], ['G05.365.5... | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Haemoglobin A1c and 5-year all-cause mortality in French type 2 diabetic patients aged 70 years and older: The GERODIAB observational cohort. | AIM: The role of glycaemic control in the mortality of elderly diabetic patients remains uncertain. GERODIAB is the first multi-centre, prospective, observational study that aims to describe the link between HbA1c and 5-year mortality in French, type 2 diabetic patients aged ?70 years.METHODS: Consecutive patients (n=9... | ['Aged', 'Aged, 80 and over', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Female', 'France', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Prospective Studies', 'Risk Factors', 'Survival Rate'] | 29,859,993 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['Z01.542.286'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Use of HEp-2 cells for improved isolation and passage of Chlamydia pneumoniae. | Chlamydia pneumoniae has proved to be difficult to isolate and propagate in cell culture. We compared the growth of three strains of C. pneumoniae, TW-183 and two clinical isolates from Brooklyn, N.Y., in five cell lines, including HeLa 229, McCoy, HL, HEp-2, and HTED, an immortalized human tracheal cell line. HEp-2 wa... | ['Bacteriological Techniques', 'Cell Line', 'Chlamydophila pneumoniae', 'Evaluation Studies as Topic', 'HeLa Cells', 'Humans'] | 1,500,500 | [['E01.370.225.875.150', 'E05.200.875.150'], ['A11.251.210'], ['B03.440.190.190.230.249'], ['E05.337', 'N05.715.360.335'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Beta-blockers after myocardial infarction: influence of first-year clinical course on long-term effectiveness. | OBJECTIVE: To develop a strategy for evaluating drug efficacy over time that accounts for heterogeneous clinical courses evolving after initiation of therapy and to demonstrate its use in assessing the long-term therapeutic benefit of propranolol after myocardial infarction.DESIGN: Analysis of data from the Beta-Blocke... | ['Adult', 'Aged', 'Arrhythmias, Cardiac', 'Bias', 'Comorbidity', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Life Tables', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Propranolol', 'Risk', 'Survival Analysis', 'Time Factors'] | 8,416,325 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['N05.715.350.150', 'N06.850.490.500'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Costs of allergic diseases from birth to two years in Finland. | OBJECTIVES: Costing studies are needed to identify the resources used for treatment and inform payers of the costs incurred. The objectives were to determine the costs of diagnosing and treating atopic dermatitis, food allergy and asthma, and to compare the share of costs to society and to the family during the first t... | ['Asthma', 'Child, Preschool', 'Cost of Illness', 'Dermatitis, Atopic', 'Female', 'Finland', 'Food Hypersensitivity', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Milk Hypersensitivity', 'Prospective Studies'] | 23,036,776 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406.448'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['Z01.542.816.186'], ['C20.543.480.3... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Successful introduction and audit of a step-down oral antibiotic strategy for low risk paediatric febrile neutropaenia in a UK, multicentre, shared care setting. | PURPOSE: Patients with febrile neutropaenia (FN) can be stratified according to their risk of significant complications, allowing reduced intensity therapy for low risk (LR) episodes. Serious events are very rare in low risk episodes making randomised trials difficult. Introduction of new evidence-based guidelines foll... | ['Administration, Oral', 'Adolescent', 'Anti-Infective Agents', 'Bone Marrow Transplantation', 'Child', 'Child, Preschool', 'Feasibility Studies', 'Fever', 'Humans', 'Infant', 'Infections', 'Neoplasms', 'Neutropenia', 'Peripheral Blood Stem Cell Transplantation', 'Risk Factors', 'Treatment Outcome'] | 19,616,427 | [['E02.319.267.100'], ['M01.060.057'], ['D27.505.954.122'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV. | The human C1q receptor (C1q-R) is a 65-70-kd, highly acidic, hydrophobic glycoprotein that is expressed on a wide variety of cell surfaces. Although the C1q-R itself appears to bind preferentially to C1q, the region of the ligand to which C1q-R binds is the primary binding site for several other molecules, including fi... | ['Amino Acid Sequence', 'Amino Acids', 'Carrier Proteins', 'Collagen', 'Complement Activating Enzymes', 'Fibronectins', 'Humans', 'Hyaluronan Receptors', 'Integrins', 'Membrane Glycoproteins', 'Mitochondrial Proteins', 'Molecular Sequence Data', 'Receptors, Complement', 'Receptors, Fibronectin', 'Receptors, Immunologic... | 1,377,218 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['D12.776.157'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D08.811.277.300', 'D12.776.124.486.274.045'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Rb1 gene inhibits the viability of retinoblastoma cells by regulating homologous recombination. | Retinoblastoma is a childhood ocular tumor caused by the inactivation of both alleles of the retinoblastoma gene (Rb1). Without Rb1 gene function, chromosomal aberrations are observed in retinoblastoma cells. The instability of the genome is closely associated with the repair of DNA double-strand breaks (DSBs). However... | ['Cell Cycle', 'Cell Line, Tumor', 'Cell Survival', 'DNA Breaks, Double-Stranded', 'DNA Repair', 'Gene Expression Regulation, Neoplastic', 'Genomic Instability', 'Homologous Recombination', 'Humans', 'Mutation', 'Retinal Neoplasms', 'Retinoblastoma', 'Retinoblastoma Protein'] | 23,670,186 | [['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['G05.200.210.220'], ['G02.111.222', 'G05.219'], ['G05.308.370'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['G05.728.615'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['C04.588.364.818', 'C11.319.475', 'C11.768.717'], ['C04.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mode of action of pesticin: N-acetylglucosaminidase activity. | Homogeneous preparations of pesticin, a bacteriocin produced by Yersinia pestis, neither significantly inhibited net synthesis of deoxyribonucleic acid, ribonucleic acid, or protein in Escherichia coli phi nor caused detectable degradation of deoxyribonucleic acid in vivo. Accordingly, its mode of action does not resem... | ['Acetylglucosaminidase', 'Bacterial Proteins', 'Bacteriocins', 'Cell Wall', 'DNA, Bacterial', 'Escherichia coli', 'Hexosaminidases', 'Peptidoglycan', 'RNA, Bacterial', 'Substrate Specificity', 'Yersinia pestis'] | 378,975 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The value of substratified combined imaging assessment with mammography and ultrasonography for Chinese women with palpable breast masses. | A 5-point breast imaging classification modified from the seven-category Breast Imaging-Reporting and Data System has been applied for mammographic and ultrasonographic examinations in patients with palpable breast masses. The aim of this study was to confirm the value of combined imaging assessment. We included 5,296 ... | ['Breast Neoplasms', 'China', 'Female', 'Humans', 'Mammography', 'Multimodal Imaging', 'Sensitivity and Specificity', 'Ultrasonography, Mammary'] | 24,519,388 | [['C04.588.180', 'C17.800.090.500'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.350.567'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['E01.370.350.850.860', ... | ['Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Celiac artery compression syndrome: successful utilization of robotic-assisted laparoscopic approach. | Median arcuate ligament (MAL) syndrome, also known as the celiac axis compression syndrome (CACS) is rare, and a topic of ongoing academic controversy. CACS is a diagnosis of exclusion, characterized by the clinical triad of postprandial abdominal pain, weight loss, and vomiting. The classic management of CACS involves... | ['Adult', 'Arterial Occlusive Diseases', 'Celiac Artery', 'Decompression, Surgical', 'Female', 'Humans', 'Laparoscopy', 'Robotics', 'Syndrome'] | 17,410,294 | [['M01.060.116'], ['C14.907.137'], ['A07.015.114.207'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['C23.550.288.500']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
Transgenerational Inheritance of Familial Lipomyelomeningocele. | Lipomyelomeningocele is a type of neural tube defect characterized by lipomatous tissue causing a defect in the vertebrae, infiltrating the dura, and tethering the spinal cord. Despite significant neurologic consequences, the underlying etiology remains poorly understood. We present a father and son with remarkably sim... | ['Carrier Proteins', 'GTPase-Activating Proteins', 'Genetic Testing', 'Humans', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Meningomyelocele', 'Pedigree'] | 29,129,155 | [['D12.776.157'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.350.825.500'], ['C10.500.680.610', 'C16.131.666.680.610'], ['E05.393.673']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Value of serum IgG subclasses in the prognosis of asthma in children with immunotherapy treatment. | Immunotherapy is an empirical treatment with proven clinical efficacy. Different results have been found when comparing the levels of the subclasses for immunoglobulin G and the clinical development during immunotherapy. A follow up study was carried out for one year on the IgG subclasses in 21 asthmatic children of bo... | ['Allergens', 'Animals', 'Asthma', 'Biomarkers', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Immunoglobulin E', 'Immunoglobulin G', 'Immunotherapy', 'Male', 'Mites', 'Prognosis'] | 9,111,871 | [['D23.050.063'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D23.101'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312', 'D12.776.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Negative Feedback Loop Between Autophagy and Immune Responses in Mycobacterium leprae Infection. | The obligate intracellular bacterium Mycobacterium leprae is the causative agent of leprosy and primarily infects macrophages, leading to irreversible nerve damage and deformities. So far, the underlying reasons allowing M. leprae to persist and propagate in macrophages, despite the presence of cellular immunity, are s... | ['Animals', 'Autophagy', 'Cytokines', 'Feedback, Physiological', 'Macrophage Activation', 'Macrophages', 'Male', 'Mice', 'Mycobacterium leprae', 'T-Lymphocytes'] | 27,854,511 | [['B01.050'], ['G04.011'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.410.732'], ['G12.287.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B03.510.024.962.500.502', 'B03.510.460.400.410.552.552.502'], ['A11.118.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of fair colonoscopy preparation on colonoscopy use and adenoma miss rates in patients undergoing outpatient colonoscopy. | BACKGROUND: The impact of fair bowel preparation on endoscopists' recommendations and adenoma miss rates in average-risk patients undergoing colonoscopy is unknown.OBJECTIVE: To assess the impact of fair bowel preparation on endoscopists' interval colonoscopy recommendations and miss rates in colonoscopies performed wi... | ['Adenoma', 'Cathartics', 'Colonoscopy', 'Colorectal Neoplasms', 'Diagnostic Errors', 'Female', 'Guideline Adherence', 'Humans', 'Male', 'Middle Aged', 'Practice Guidelines as Topic', 'Retrospective Studies', 'Time Factors'] | 23,642,491 | [['C04.557.470.035'], ['D27.505.954.483.396'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.354', 'N02.42... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
N-Terminal Coiled-Coil Structure of ATPase Subunits of 26S Proteasome Is Crucial for Proteasome Function. | The proteasome is an essential proteolytic machine in eukaryotic cells, where it removes damaged proteins and regulates many cellular activities by degrading ubiquitinated proteins. Its heterohexameric AAA+ ATPase Rpt subunits play a central role in proteasome activity by the engagement of substrate unfolding and trans... | ['Adenosine Triphosphatases', 'Cytoplasm', 'DNA Mutational Analysis', 'Proteasome Endopeptidase Complex', 'Protein Structure, Tertiary', 'Saccharomyces cerevisiae'] | 26,208,326 | [['D08.811.277.040.025'], ['A11.284.430.214'], ['E05.393.760.700.300'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['G02.111.570.820.709.610'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unusual presentation of primary amoebic meningoencephalitis--a serious diagnostic and therapeutic problem. | A fatal case of meningo-encephalitis due to Amoeba naegleria is discussed. It was a problem for diagnosis because of its unusual presentation. The patient, a young pregnant female presented with pyrexia, severe headache, and photophobia. Anti-biotic therapy was started after a provisional diagnosis of acute pyogenic me... | ['Adult', 'Amebiasis', 'Chloramphenicol', 'Drug Therapy, Combination', 'Female', 'Humans', 'Isoniazid', 'Meningoencephalitis', 'Metronidazole', 'Penicillins', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Streptomycin', 'Sulfadiazine'] | 660,712 | [['M01.060.116'], ['C01.610.752.049'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['C01.207.245.550', 'C01.207.570', 'C10.228.140.430.550', 'C10.228.228.245.550', ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Recombinant IgA is sufficient to prevent influenza virus transmission in guinea pigs. | A serum hemagglutination inhibition (HAI) titer of 40 or greater is thought to be associated with reduced influenza virus pathogenesis in humans and is often used as a correlate of protection in influenza vaccine studies. We have previously demonstrated that intramuscular vaccination of guinea pigs with inactivated inf... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Neutralizing', 'Base Sequence', 'Cloning, Molecular', 'Dogs', 'Enzyme-Linked Immunosorbent Assay', 'Ferrets', 'Guinea Pigs', 'HEK293 Cells', 'Hemagglutination Inhibition Tests', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Influenza A Virus, H1N1 Subtype', 'Madin... | 23,698,296 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B01.050.150.900.649.313.750.250.216.20... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
LGR7-truncate is a splice variant of the relaxin receptor LGR7 and is a relaxin antagonist in vitro. | The relaxin receptor (LGR7) and the insulin-like peptide 3 (INSL3) receptor (LGR8) are unique LGR family members in possessing a single, functionally important amino terminal LDL-A module.1 Mouse and rat cDNA was screened for LGR7 and LGR7 splice variant expression. A uterus-specific exon 4 deleted variant was identifi... | ['Alternative Splicing', 'Animals', 'Cell Line', 'Cyclic AMP', 'Female', 'Humans', 'Mice', 'RNA, Messenger', 'Rats', 'Receptors, G-Protein-Coupled', 'Receptors, Peptide', 'Relaxin', 'Uterus'] | 15,956,683 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['A11.251.210'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.444.735.544'], ['B01.050... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A national analysis of the relationship between hospital volume, academic center status, and surgical outcomes for abdominal hysterectomy done for leiomyoma. | BACKGROUND: Volume-to-outcomes relationships have been established for high-risk surgical procedures. To determine whether hospital volume and academic center status affect surgical outcomes in a lower-risk procedure, morbidity and mortality in patients undergoing abdominal hysterectomy for leiomyoma were evaluated.STU... | ['Academic Medical Centers', 'Adult', 'Female', 'Hospitals, University', 'Humans', 'Hysterectomy', 'Leiomyoma', 'Logistic Models', 'Middle Aged', 'Morbidity', 'Odds Ratio', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Retrospective Studies', 'United States', 'Uterine Neoplasms'] | 19,476,796 | [['N02.278.020'], ['M01.060.116'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C04.557.450.590.450'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.7... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Integrated microchip-device for the digestion, separation and postcolumn labeling of proteins and peptides. | A microchip device was demonstrated that integrated enzymatic reactions, electrophoretic separation of the reactants from the products and post-separation labeling of proteins and peptides prior to detection. A tryptic digestion of oxidized insulin B-chain was performed in 15 min under stopped flow conditions in a heat... | ['Hydrolysis', 'Miniaturization', 'Naphthalenes', 'Peptides', 'Proteins', 'Semiconductors'] | 10,997,719 | [['G02.380'], ['J01.897.520'], ['D02.455.426.559.847.638', 'D04.615.638'], ['D12.644'], ['D12.776'], ['E07.305.625']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Viscosity and elasticity during collagen assembly in vitro: relevance to matrix-driven translocation. | In order to better understand the gelation process associated with collagen assembly, and the mechanism of the in vitro morphogenetic phenomenon of "matrix-driven translocation" [S.A. Newman et al. (1985) Science, 228, 885-889], the viscosity and elastic modulus of assembling collagen matrices in the presence and absen... | ['Animals', 'Cold Temperature', 'Collagen', 'Elasticity', 'In Vitro Techniques', 'Mathematics', 'Polystyrenes', 'Rats', 'Viscosity'] | 10,917,694 | [['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.374.590'], ['E05.481'], ['H01.548'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.716.579', 'J01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
N-terminal lysines are essential for protein translocation via a modified ERAD system in complex plastids. | Nuclear-encoded pre-proteins being imported into complex plastids of red algal origin have to cross up to five membranes. Thereby, transport across the second outermost or periplastidal membrane (PPM) is facilitated by SELMA (symbiont-specific ERAD-like machinery), an endoplasmic reticulum-associated degradation (ERAD)... | ['Algal Proteins', 'Intracellular Membranes', 'Models, Biological', 'Mucoproteins', 'Plastids', 'Protein Transport', 'Rhodophyta'] | 25,644,868 | [['D12.776.037'], ['A11.284.149.450', 'A11.284.835.514'], ['E05.599.395'], ['D12.776.395.560'], ['A11.284.430.214.190.875.700'], ['G03.143.700'], ['B01.650.700']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Core temperature measurement in therapeutic hypothermia according to different phases: comparison of bladder, rectal, and tympanic versus pulmonary artery methods. | PURPOSE: Comparisons of bladder, rectal and tympanic temperatures versus pulmonary artery (PA) temperature during different therapeutic hypothermia (TH) phases.METHODS: Twenty-one patients admitted to our emergency department (ED) after out-of-hospital cardiac arrests were included in this study. For comparison, the te... | ['Adult', 'Aged', 'Body Temperature', 'Catheterization, Swan-Ganz', 'Cohort Studies', 'Female', 'Humans', 'Hypothermia, Induced', 'Male', 'Middle Aged', 'Out-of-Hospital Cardiac Arrest', 'Prospective Studies', 'Pulmonary Artery', 'Rectum', 'Rewarming', 'Tympanic Membrane', 'Urinary Bladder'] | 23,306,812 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.374', 'G07.110'], ['E01.370.370.380.140.210', 'E02.148.224.165', 'E02.148.442.165', 'E04.100.814.529.937.165', 'E04.502.382.937.165', 'E05.157.250.165', 'E05.157.375.165'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Suppression of efflux transporters in the intestines of endotoxin-treated rats. | Infection and inflammation suppress the expression and activity of several drug transporters in the liver. In the intestine, P-glycoprotein (PGP/mdr1) and the multidrug resistance-associated protein 2 (MRP2) are important barriers to the absorption of many clinically important drugs. The protein expression and activity... | ['ATP Binding Cassette Transporter, Subfamily B', 'ATP Binding Cassette Transporter, Subfamily B, Member 1', 'ATP-Binding Cassette Transporters', 'Animals', 'Biological Transport', 'Drug Resistance, Multiple', 'Endotoxins', 'Fluoresceins', 'Gene Expression', 'Ileum', 'Infections', 'Inflammation', 'Lipopolysaccharides',... | 22,387,888 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Individual differences in the concordance of self-reports and official records. | BACKGROUND: Although self-reported and official measures of criminal behaviour are highly correlated, the concordance between self-reports and official records appears to vary across the population. Few studies, however, have considered the range of individual traits and characteristics that might influence the relativ... | ['Adolescent', 'Adolescent Behavior', 'Aggression', 'Australia', 'Crime', 'Criminal Law', 'Criminals', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Personality', 'Personality Inventory', 'Prevalence', 'Psychology, Adolescent', 'Risk Factors', 'Self Concept', 'Self Report', 'Temperament', 'Violence', 'Young Adul... | 25,294,163 | [['M01.060.057'], ['F01.145.022'], ['F01.145.126.125', 'F01.145.813.045'], ['Z01.639.100', 'Z01.678.100.373'], ['I01.198.240', 'I01.880.735.191'], ['I01.198.290', 'I01.880.604.583.100'], ['M01.142'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Outpatient management of cervical intraepithelial neoplasia. A summary of 279 cases. | Two hundred seventy-nine patients with cervical condylomas or cervical intraepithelial neoplasia (CIN) were treated as outpatients with cryotherapy. Every patient followed received a Papanicolaou smear, colposcopic evaluation, cervical biopsy and endocervical curettage four months following treatment. The treatment fai... | ['Ambulatory Surgical Procedures', 'Biopsy', 'Carcinoma in Situ', 'Colposcopy', 'Condylomata Acuminata', 'Cryosurgery', 'Female', 'Follow-Up Studies', 'Humans', 'Papanicolaou Test', 'Postoperative Care', 'Time Factors', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 4,009,553 | [['E04.030'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.240'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['C01.221.812.640.220', 'C01.778.640.220'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Overproduction and partial purification of the Norrie disease gene product, norrin, from a recombinant baculovirus. | Abnormal vascularization of the peripheral retina and retinal detachment are common clinical characteristics of Norrie disease (ND), familial exudative vitreoretinopathy, Coats' disease, and retinopathy of prematurity. Although little is known about the molecular basis of these diseases, studies have shown that all of ... | ['Abnormalities, Multiple', 'Baculoviridae', 'Blindness', 'Cloning, Molecular', 'Eye Proteins', 'Nerve Tissue Proteins', 'Protein Engineering', 'Recombinant Proteins', 'Retinal Dysplasia', 'Syndrome', 'Transfection'] | 14,630,047 | [['C16.131.077'], ['B04.280.065', 'B04.525.100'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['E05.393.220'], ['D12.776.306'], ['D12.776.631'], ['E05.393.420.601'], ['D12.776.828'], ['C11.250.666', 'C11.270.660', 'C11.768.660', 'C16.131.384.784', 'C16.320.290.660'], ['C23.550.288.500'], ['E05.39... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of type I interferon genes and interferon-inducible genes in embryonal stem cells devoid of interferon regulatory factor 1. | Overexpression of interferon regulatory factor 1 (IRF-1) can induce expression of the interferon (IFN) beta gene, at least in certain cells. A role of IRF-1 in the activation of IFN-alpha genes has also been claimed. We have generated embryonal stem cells in which both IRF-1 alleles were disrupted. In undifferentiated ... | ['Animals', 'Cell Differentiation', 'Clone Cells', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Genomic Library', 'Humans', 'Interferon Regulatory Factor-1', 'Interferon Type I', 'Interferon-alpha', 'Interferon-beta', 'Mice', 'Mice, Inbred C57BL', 'Newcastle disease virus', 'Phosphoproteins', 'Recombinant Pro... | 8,265,581 | [['B01.050'], ['G04.152'], ['A11.251.353'], ['D12.776.260'], ['G05.308'], ['G05.360.325.425', 'G05.360.340.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.024.302.124', 'D12.776.157.057.050.124', 'D12.776.260.108.374', 'D12.776.260.504.124', 'D12.776.476.024.385.124', 'D12.776.930.127.374', 'D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of starch and lipid accumulation in a microalga Chlorella sorokiniana. | Microalgae have attracted growing attention due to their potential in biofuel feedstock production. However, current understanding of the regulatory mechanisms for lipid biosynthesis and storage in microalgae is still limited. This study revealed that the microalga Chlorella sorokiniana showed sequential accumulation o... | ['Chlorella', 'Light', 'Lipid Metabolism', 'Microalgae', 'Nitrogen', 'Photosynthesis', 'Starch'] | 25,616,239 | [['B01.650.940.150.469'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G03.458'], ['B05.080.500.600.500'], ['D01.268.604', 'D01.362.625'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['D05.750.078.562.855', 'D09.301.91... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extra-anatomic renal revascularization in patients with renal artery stenosis and abdominal aortic occlusion. | Thirteen patients with atherosclerotic renal artery stenosis and total abdominal aortic occlusion underwent extra-anatomic surgical renal revascularization without aortic replacement. Renal artery stenosis was present unilaterally (n = 2), bilaterally (n = 7), or in a solitary kidney (n = 4). Surgical renal revasculari... | ['Adult', 'Aged', 'Anastomosis, Surgical', 'Aorta, Abdominal', 'Aortic Diseases', 'Arterial Occlusive Diseases', 'Arteriosclerosis', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Renal Artery Obstruction', 'Vascular Surgical Procedures'] | 8,256,395 | [['M01.060.116'], ['M01.060.116.100'], ['E04.035'], ['A07.015.114.056.205'], ['C14.907.109'], ['C14.907.137'], ['C14.907.137.126'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.419.775', 'C13.35... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Semiquantitative evaluation of mRNAs for the membranous form of immunoglobulin heavy chain is useful for investigating the etiology in CVID. | Common variable immunodeficiency (CVID) is a primary antibody deficiency syndrome characterized by defective B-cell maturation and antibody formation resulting in low serum antibody levels of all immunoglobulin (Ig) isotypes. To investigate the pathogenesis of CVID, we developed a set of competitive polymerase chain re... | ['Child', 'Common Variable Immunodeficiency', 'Female', 'Humans', 'Immunoglobulin Heavy Chains', 'Infant', 'RNA, Messenger', 'Receptors, Antigen, B-Cell', 'Reverse Transcriptase Polymerase Chain Reaction'] | 14,636,421 | [['M01.060.406'], ['C20.673.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.705.500', 'D12.776.124.790.651.705.500', 'D12.776.377.715.548.705.500'], ['M01.060.703'], ['D13.444.735.544'], ['D12.776.124.790.651.950', 'D12.776.377.715.548.950', 'D12.776.543.750.705.816.821'], ['E05.393.620.50... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acute effects of low-dose interferon-alpha on serum cortisol and plasma interleukin-6. | Major depression is associated with both hypothalamic-pituitary-adrenal (HPA) axis overactivity and immune system activation. Depression is a common occurrence following interferon (IFN)-a treatment. While IFN-alpha is known to stimulate the HPA axis, little is known about the effects of exogenous IFN-a in humans on th... | ['Adult', 'Cross-Over Studies', 'Depressive Disorder, Major', 'Double-Blind Method', 'Female', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Injections, Subcutaneous', 'Interferon alpha-2', 'Interferon-alpha', 'Interleukin-6', 'Male', 'Pituitary-Adrenal System', 'Recombinant Proteins'] | 12,236,630 | [['M01.060.116'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['F03.600.300.375'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct chiral assay of tramadol and detection of the phase II metabolite O-demethyl tramadol glucuronide in human urine using capillary electrophoresis with laser-induced native fluorescence detection. | A chiral separation using carboxymethyl-beta-cyclodextrin and methyl-beta-cyclodextrin for the direct assay of tramadol in human urine by capillary electrophoresis (CE) with laser-induced native fluorescence detection was developed. Furthermore, the phase II metabolite O-demethyl tramadol glucuronide was determined fro... | ['Analgesics, Opioid', 'Electrophoresis, Capillary', 'Glucuronides', 'Humans', 'Lasers', 'Reference Values', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrometry, Fluorescence', 'Stereoisomerism', 'Tramadol'] | 11,817,307 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E05.196.401.190', 'E05.301.300.190'], ['D02.241.081.844.915.162.500', 'D02.241.152.811.162.750', 'D02.241.511.902.915.162.750', 'D09.811.922.162.750'], ['B01.050.150.900.649.313.988.400.112.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[PERIPHERAL AUTONOMOUS REGULATION OF SINUS (SINOATRIAL) NODE IN TYPE 1 AND 2 DIABETES MELLITUS]. | The aim of this work was to study peripheral vegetative regulation of pacemaker activity of the sinus (sinoatrial) node (SN) by high resolution analysis of cardiac rhythm variability (CRV) in patients with type 1 and 2 diabetes mellitus (DM). All CRV waves in the temporal and spectral regions were shown to be reduced. ... | ['Adult', 'Autonomic Nervous System', 'Diabetes Mellitus', 'Heart Function Tests', 'Humans', 'Sinoatrial Node'] | 26,155,708 | [['M01.060.116'], ['A08.800.050'], ['C18.452.394.750', 'C19.246'], ['E01.370.370.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.409.819']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spatiotemporal patterns of fibronectin distribution during embryonic development. I. Chick limbs. | It has been suggested that an extracellular matrix - and cell surface - associated glycoprotein, fibronectin, plays a role in the positioning of cells in morphogenesis and in the maintenance of orderly tissue organization. In the present study the appearance and distribution of fibronectin during in ovo chick limb deve... | ['Animals', 'Cartilage', 'Cell Differentiation', 'Chick Embryo', 'Electrophoresis, Polyacrylamide Gel', 'Fibronectins', 'Fluorescent Antibody Technique', 'Hindlimb', 'Hyaluronoglucosaminidase', 'Morphogenesis'] | 7,031,164 | [['B01.050'], ['A02.165', 'A10.165.382'], ['G04.152'], ['A13.350.150', 'A16.331.200'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mixed micelles based on a pH-sensitive prodrug and TPGS for enhancing drug efficacy against multidrug-resistant cancer cells. | In this study, we prepared mixed micelles composed of a pH-sensitive poly(ethylene glycol)-doxorubicin conjugate prodrug and d-alpha-tocopheryl polyethylene glycol succinate (TPGS). The average hydrodynamic size of the mixed micelles was approximately 144nm, measured by dynamic light scattering. In an MTT assay the pH-... | ['Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Survival', 'Doxorubicin', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Humans', 'Hydrogen-Ion Concentration', 'MCF-7 Cells', 'Micelles', 'Polyethylene Glycols', 'Vitamin E'] | 28,823,972 | [['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G07.690.773.984.300'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['A11.251.210.190.630'], ['D05.374', '... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Labrafil--a new adjuvant for peptide-specific oral tolerance in rat experimental autoimmune uveitis. | Application of soluble antigen via the oral route results in systemic antigen-specific tolerance, a therapeutic approach that has already been used for uveitis patients. In the Lewis rat experimental autoimmune uveitis (EAU) can be induced by active immunisation with retinal antigens such as retinal soluble antigen (S-... | ['Administration, Oral', 'Amino Acid Sequence', 'Animals', 'Autoimmune Diseases', 'Eye Proteins', 'Female', 'Glycerides', 'Immune Tolerance', 'Male', 'Molecular Sequence Data', 'Peptide Fragments', 'Polyethylene Glycols', 'Rats', 'Rats, Inbred Lew', 'Surface-Active Agents', 'Uveitis'] | 18,042,397 | [['E02.319.267.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['C20.111'], ['D12.776.306'], ['D10.351'], ['G12.535.425'], ['L01.453.245.667'], ['D12.644.541'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Simultaneous Determination of 11 High-Polarity Components from Fructus Corni: A Quantitative LC-MS/MS Method for Improved Quality Control. | Fructus Corni, the dried ripe sarcocarp of Cornus officinalis Sieb.et Zucc (Cornaceae), is widely used in traditional medicine. Pharmacological studies to date have attributed many biological effects to the high-polarity components. However, current quality control methods focus on only several iridoid glycoside compon... | ['Chromatography, High Pressure Liquid', 'Cornus', 'Drugs, Chinese Herbal', 'Limit of Detection', 'Linear Models', 'Quality Control', 'Reproducibility of Results', 'Tandem Mass Spectrometry'] | 29,036,589 | [['E05.196.181.400.300'], ['B01.650.940.800.575.912.250.250.299'], ['D20.215.784.500.350', 'D26.335'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Paediatric tracheostomy in Hospital University Kebangsaan Malaysia - a changing trend. | Indication for pediatric tracheostomy has changed. Upper airway obstruction secondary to infectious disorders is no longer the commonest indication. The aim of this study was to establish data on indications, outcome and complications of pediatric tracheostomy. A retrospective analysis of pediatric tracheostomies carri... | ['Adolescent', 'Adult', 'Airway Obstruction', 'Child', 'Child, Preschool', 'Female', 'Hospitals, University', 'Humans', 'Infant', 'Infant, Newborn', 'Malaysia', 'Male', 'Retrospective Studies', 'Tracheostomy'] | 16,898,313 | [['M01.060.057'], ['M01.060.116'], ['C08.618.846.185'], ['M01.060.406'], ['M01.060.406.448'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['Z01.252.145.487'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.33... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Salinity and temperature variations reflecting on cellular PCNA, IGF-I and II expressions, body growth and muscle cellularity of a freshwater fish larvae. | The present study assessed the influence of salinity and temperature on body growth and on muscle cellularity of Lophiosilurus alexaxdri vitelinic larvae. Slightly salted environments negatively influenced body growth of freshwater fish larvae and we observed that those conditions notably act as an environmental influe... | ['Animals', 'Biometry', 'Catfishes', 'Fish Proteins', 'Fluorescence', 'Fresh Water', 'Insulin-Like Growth Factor I', 'Insulin-Like Growth Factor II', 'Larva', 'Linear Models', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Principal Component Analysis', 'Proliferating Cell Nuclear Antigen', 'Salinity', 'Temperature'] | 24,747,484 | [['B01.050'], ['E05.318.740.225', 'N06.850.505.200'], ['B01.050.150.900.493.080'], ['D12.776.325'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G16.500.275.280', 'N06.230.232'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D12.644.276.937.420', 'D12.776.124.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anal encirclement with polypropylene mesh for rectal prolapse and incontinence. | Seventeen selected patients (mean age, 74 years)--14 with rectal prolapse and 3 with persisting anal incontinence after previous operations--underwent high anal encirclement with polypropylene mesh. There was no operative mortality. Prolapse recurred in 2 (15 percent) of the 13 patients followed up for 6 months or more... | ['Aged', 'Aged, 80 and over', 'Colorectal Surgery', 'Fecal Impaction', 'Fecal Incontinence', 'Female', 'Humans', 'Middle Aged', 'Polypropylenes', 'Postoperative Complications', 'Rectal Prolapse', 'Recurrence', 'Reoperation', 'Surgical Mesh'] | 1,914,725 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['H02.403.810.208'], ['C06.405.469.531.424'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.455.326.271.665.590', 'D05.750.716.550', 'D25.720.716.550', 'J01.637.051.720.716.550'], ['C23.550.767'], ['C06.405.469.860.800... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 |
Reversible inhibition of the hydrocortisone induction of glycerol phosphate dehydrogenase by cytochalasin B in rat glial C6 cells. | The hydrocortisone (HC) induction of glycerol phosphate dehydrogenase (GPDH; EC 1.1.1.8) in rat glial C6 cells was inhibited reversibly and in a dose-dependent manner by cytochalasin B (CB). CB had no effect on basal level GPDH, total cellular RNA, DNA or protein content nor did it act as a general inhibitor of the rat... | ['Animals', 'Cell Line', 'Cell Nucleus', 'Colchicine', 'Cytochalasin B', 'Dimethyl Sulfoxide', 'Drug Interactions', 'Enzyme Induction', 'Glycerolphosphate Dehydrogenase', 'Hydrocortisone', 'Neuroglia', 'Pyruvates', 'Rats', 'Time Factors'] | 563,407 | [['B01.050'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D03.132.225'], ['D03.633.100.473.231.370', 'D23.946.587.370.370'], ['D02.886.640.150'], ['G07.690.773.968'], ['G05.308.320.200'], ['D08.811.682.047.150.700.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-performance liquid chromatographic determination of taurine in biological fluids by post-column fluorescence reaction with thiamine. | A high-performance liquid chromatographic method is described for the selective determination of taurine in biological fluids by post-column fluorescence reaction. Taurine was separated on an adsorption-distribution type Shodex Ionpac KC-811 column. Then it was converted with hypochlorite into the corresponding N-chlor... | ['Chromatography, High Pressure Liquid', 'Fluorescence', 'Humans', 'Male', 'Taurine', 'Thiamine'] | 1,770,098 | [['E05.196.181.400.300'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.146.100.850', 'D02.886.645.600.055.850'], ['D02.886.675.900', 'D03.383.129.708.900', 'D03.383.742.795']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elution of antibiotics from poly(methyl methacrylate) bone cement after extended implantation does not necessarily clear the infection despite susceptibility of the clinical isolates. | Chronic orthopedic infections are commonly caused by bacterial biofilms, which are recalcitrant to antibiotic treatment. In many cases, the revision procedure for periprosthetic joint infection or trauma cases includes the implantation of antibiotic-loaded bone cement to kill infecting bacteria via the elution of a str... | ['Adult', 'Aged', 'Amputation, Traumatic', 'Anti-Bacterial Agents', 'Arthroplasty, Replacement, Knee', 'Bacterial Infections', 'Bone Cements', 'Female', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Polymethyl Methacrylate', 'Prosthesis-Related Infections', 'Pseudomonas aeruginosa', 'Staphylococcus aureus', 'Strept... | 26,527,622 | [['M01.060.116'], ['M01.060.116.100'], ['C26.062'], ['D27.505.954.122.085'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['C01.150.252'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.22... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
"Biomimetic-electrochemical-sensory-platform" for biomolecule free cocaine testing. | A biomimetic cocaine sensor was fabricated by using poly(p-phenylene) (PPP) with cyclodextrin (CD) units in the backbone and poly(ethylene glycol) (PEG) side chains (PPP-CD-g-PEG). The sensory platform was constructed by one step surface modification of glassy carbon electrode with PPP-CD-g-PEG by drop coating. The ele... | ['Biomimetics', 'Cocaine', 'Electrochemical Techniques', 'Electrodes', 'Nanotubes, Carbon', 'beta-Cyclodextrins'] | 29,853,084 | [['H01.158.550.100', 'J01.897.120.100'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['E05.301'], ['E07.305.250'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D04.345.103.333', 'D09.301.915.400.375.333', 'D09.698.365.855.400.375.333']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Are Belgian military students in medical sciences better educated in disaster medicine than their civilian colleagues? | INTRODUCTION: Historically, medical students have been deployed to care for disaster victims but may not have been properly educated to do so. A previous evaluation of senior civilian medical students in Belgium revealed that they are woefully unprepared. Based on the nature of their military training, we hypothesised ... | ['Belgium', 'Clinical Competence', 'Cross-Sectional Studies', 'Curriculum', 'Disaster Medicine', 'Education, Medical, Undergraduate', 'Female', 'Humans', 'Male', 'Military Personnel', 'Students, Medical', 'Young Adult'] | 26,759,501 | [['Z01.542.115'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I02.158'], ['H02.403.230'], ['I02.358.399.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['M01.848.769.602'], ['M01.060.116.815']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Oxidant-mediated inhibition of ligand uptake by the macrophage mannose receptor. | We have investigated the effect of oxidants on ligand recognition and internalization by the macrophage mannose receptor. Rat bone marrow macrophages were treated with increasing concentrations of H2O2 for 30 min at 37 degrees C. Fifty percent inhibition of ligand uptake was observed at 250 microM, with only 10% of con... | ['Animals', 'Bone Marrow Cells', 'Catalase', 'Glucose Oxidase', 'Glucuronidase', 'Hydrogen Peroxide', 'Lectins, C-Type', 'Ligands', 'Macrophages', 'Mannose-Binding Lectins', 'Microscopy, Electron', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Rats', 'Receptors, Cell Surface', 'Receptors, Immunologic', 'Su... | 3,335,543 | [['B01.050'], ['A11.148', 'A15.378.316'], ['D08.811.682.732.332'], ['D08.811.682.047.239'], ['D08.811.277.450.426'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D12.776.503.280'], ['D27.720.470.480'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. | AIM: To establish the methylation profile of the promoter CpG islands of 31 genes that might play etiological roles in colon carcinogenesis.METHODS: The methylation specific PCR in conjunction of sequencing verification was used to establish the methylation-profile of the promoter CpG islands of 31 genes in colorectal ... | ['Adenoma', 'Base Sequence', 'Colorectal Neoplasms', 'CpG Islands', 'DNA Methylation', 'Gene Expression Profiling', 'Humans', 'Molecular Sequence Data', 'Prognosis', 'Promoter Regions, Genetic'] | 15,526,363 | [['C04.557.470.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.16... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Natriuretic peptides stimulate the cardiac sodium pump via NPR-C-coupled NOS activation. | Natriuretic peptides (NPs) and their receptors (NPRs) are expressed in the heart, but their effects on myocyte function are poorly understood. Because NPRs are coupled to synthesis of cGMP, an activator of the sarcolemmal Na(+)-K(+) pump, we examined whether atrial natriuretic peptide (ANP) regulates the pump. We volta... | ['Animals', 'Cyclic GMP-Dependent Protein Kinases', 'Enzyme Activation', 'Guanylate Cyclase', 'Male', 'Myocardium', 'Natriuretic Peptides', 'Nitric Oxide Synthase', 'Protein Isoforms', 'Rabbits', 'Receptors, Atrial Natriuretic Factor', 'Receptors, Cytoplasmic and Nuclear', 'Sodium-Potassium-Exchanging ATPase', 'Soluble... | 18,272,821 | [['B01.050'], ['D08.811.913.696.620.682.700.150.150', 'D12.644.360.200.150', 'D12.776.476.200.150'], ['G02.111.263', 'G03.328'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D06.472.699.584', 'D12.644.548.585'], ['D08.811.682.664.500.772'], ['D12.77... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of human monocytes by free muramyl dipeptide (MDP). | Activation of human monocytes with MDP (N-acetylmuramyl-L-alanyl-D-isoglutamine) 1-100 micrograms per ml for 48 h in vitro enhanced the cytostatic activity against the target cell line K-562, while cytolysis remained unchanged. Catalase, 600 SU per ml, had no inhibitory effect on the cytostasis mediated by MDP-activate... | ['Acetylmuramyl-Alanyl-Isoglutamine', 'Catalase', 'Cell Line', 'Cytotoxicity, Immunologic', 'Humans', 'Hydrogen Peroxide', 'Luminescent Measurements', 'Lymphocyte Activation', 'Monocytes', 'Superoxide Dismutase'] | 6,507,104 | [['D09.067.550.050', 'D09.811.522.050', 'D12.644.233.050'], ['D08.811.682.732.332'], ['A11.251.210'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['E05.196.712.516'], ['E01.370.225.812.482', 'E05.200.812.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chromosome 2 hypersensitivity and clonal development in murine radiation acute myeloid leukaemia. | Acute myeloid leukaemias induced by ionizing radiation in mouse are characterized by chromosome (chr) 2 aberrations. While it is known that chr 2 aberrations form early and in abundance post-irradiation, unequivocal evidence for hypersensitivity of chr 2 in the first post-irradiation mitoses is lacking. Here it is esta... | ['Acute Disease', 'Animals', 'Chromosome Aberrations', 'Clone Cells', 'In Situ Hybridization, Fluorescence', 'Leukemia, Myeloid', 'Leukemia, Radiation-Induced', 'Mice', 'Mice, Inbred CBA', 'Radiation Tolerance'] | 9,269,311 | [['C23.550.291.125'], ['B01.050'], ['C23.550.210', 'G05.365.590.175'], ['A11.251.353'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['C04.557.337.539'], ['C04.557.337.650', 'C04.682.512', ... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cyclosporine in heart transplant recipients: an exercise study of vasopressor effects. | The possible vasopressor effect of cyclosporine (CS) on both the systemic and pulmonary vascular beds has been investigated during bicycle exercise in 12 heart transplant recipients (mean age, 41 years) using pulmonary artery catheter measurements. Eight patients were taking cyclosporine and six azathioprine and predni... | ['Adult', 'Azathioprine', 'Blood Pressure', 'Cardiac Output', 'Cyclosporine', 'Electrocardiography', 'Exercise Test', 'Female', 'Heart Transplantation', 'Humans', 'Male', 'Middle Aged', 'Prednisolone', 'Pulmonary Wedge Pressure'] | 1,600,994 | [['M01.060.116'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.150', 'G09.330.380.124'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of poultry litter land application on the concentrations of estrogens in water and sediment within a watershed. | This research studied the occurrence of estrogens in the Upper Satilla watershed, Georgia, USA, which was impacted by poultry litter land application and discharge from a sewage treatment plant (STP) receiving poultry wastes. Over 14 months, four estrogens in stream water, sediment, suspended particles, and STP samples... | ['Animals', 'Environmental Monitoring', 'Estradiol Congeners', 'Estrogens', 'Fertilizers', 'Geologic Sediments', 'Georgia', 'Manure', 'Poultry', 'Rivers', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 23,695,171 | [['B01.050'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D06.472.334.851.437'], ['D27.505.696.399.472.277'], ['D27.720.031.400'], ['G01.311.330', 'G16.500.320'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['D20.601'], ['B01.050.050.116.625', 'B01.050.150.900.248.690', 'G07.203.300.600.750', 'J02.500.600... | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Individual and Neighborhood Characteristics Associated with HIV Among Black and Latino Adults Who Use Drugs and Unaware of Their HIV-Positive Status, New York City, 2000-2004. | With mounting evidence of how neighborhood socioeconomic context influences individual behavior, investigation of neighborhood social context and sex/drug use risk behavior could help explain and provide insight into solutions to solve persistent racial disparities in HIV. Interviewer-administered surveys and HIV testi... | ['Adult', 'African Americans', 'HIV Infections', 'Hispanic Americans', 'Humans', 'Male', 'New York City', 'Residence Characteristics', 'Sexual and Gender Minorities', 'Substance-Related Disorders'] | 27,294,761 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', '... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Volume changes in the menisci and articular cartilage of runners: an in vivo investigation based on 3-D magnetic resonance imaging. | BACKGROUND: Articular cartilage contributes to transferring enormous loads as uniformly as possible from one skeletal segment to the next. Whether it manages this task when subjected to the high repetitive loading cycles occurring during long-distance running and can remain intact is still the topic of controversy.PURP... | ['Adult', 'Athletic Injuries', 'Humans', 'Knee Injuries', 'Knee Joint', 'Magnetic Resonance Imaging', 'Male', 'Menisci, Tibial', 'Osteoarthritis', 'Patella', 'Risk Assessment', 'Risk Factors', 'Running', 'Sports Medicine', 'Tibia'] | 16,436,539 | [['M01.060.116'], ['C26.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.835.583.475'], ['E01.370.350.825.500'], ['A02.165.308.538.500', 'A02.835.583.475.590', 'A10.165.382.350.163.500'], ['C05.550.114.606', 'C05.799.613'], ['A02.835.232.043.650.624', 'A02.835.232.730.500'], ['E05.318.740.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Prognostic significance of cardiac cinefluoroscopy for coronary calcific deposits in asymptomatic high risk subjects. | OBJECTIVES: This research investigated the prognostic significance of radiographically detectable coronary calcific deposits.BACKGROUND: Coronary calcific deposits are almost always associated with coronary atherosclerosis. We investigated the association between fluoroscopically determined coronary calcium and coronar... | ['Aged', 'Calcinosis', 'Cineradiography', 'Coronary Disease', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Prognosis', 'Prospective Studies', 'Risk Factors'] | 8,034,867 | [['M01.060.116.100'], ['C18.452.174.130'], ['E01.370.350.700.225.469'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improving clinical examination in acute tibial fractures by enhancing visual cues: the case for always 'cutting back' a tibial back-slab and marking the dorsalis pedis pulse. | Look, feel, move is a simple and widely taught sequence to be followed when undertaking a clinical examination in orthopaedics (Maher et al., 1994; McRae, 1999; Solomon et al., 2010). The splinting of an acute tibial fracture with a posterior back-slab is also common practice; with the most commonly taught design invol... | ['Acute Disease', 'Clinical Competence', 'Foot', 'Humans', 'Nursing Diagnosis', 'Palpation', 'Tibial Fractures'] | 27,236,718 | [['C23.550.291.125'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.508.480.110'], ['E01.370.600.600'], ['C26.404.875', 'C26.558.857']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Grief resolution among the bereaved in hospice and hospital wards. | As a study of grief resolution, 71 surviving spouses of patients who had died in a hospice or a hospital acute care oncology ward were interviewed in their homes 6 and 12 months following the death of their mate. It was hypothesized that hospice survivors would score significantly lower on measures of depression and an... | ['Acute Disease', 'Anxiety', 'Depression', 'Female', 'Grief', 'Hospices', 'Hospital Units', 'Humans', 'Interpersonal Relations', 'Interviews as Topic', 'Longitudinal Studies', 'Male', 'Neoplasms'] | 2,024,139 | [['C23.550.291.125'], ['F01.470.132'], ['F01.145.126.350'], ['F01.470.142.110'], ['N02.278.421.556.185', 'N02.421.143.550'], ['N02.278.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E05.318.372.500.750.500'... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy. | Autophagy plays a key role during Salmonella infection, by eliminating these pathogens following escape into the cytosol. In this process, selective autophagy receptors, including the myosin VI adaptor proteins optineurin and NDP52, have been shown to recognize cytosolic pathogens. Here, we demonstrate that myosin VI a... | ['Animals', 'Autophagy', 'Blotting, Western', 'Cells, Cultured', 'Gene Knockdown Techniques', 'HeLa Cells', 'Humans', 'Immunoprecipitation', 'Intracellular Signaling Peptides and Proteins', 'Magnetic Resonance Spectroscopy', 'Mice', 'Microscopy, Fluorescence', 'Molecular Sequence Data', 'Myosin Heavy Chains', 'Neoplasm... | 26,451,915 | [['B01.050'], ['G04.011'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['E05.393.335.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.150.639', 'E05.478.605'], ['D12.644.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Retrospective analyses of postoperative survival of laryngeal carcinoma patients at late stage]. | OBJECTIVE: To compare the postoperative survival rate of laryngeal carcinoma patient at stage III or IV whom accepted partial laryngectomy and total laryngectomy.METHOD: We performed a retrospective cohort follow-up study of 126 patients of stage III or IV who underwent operation for laryngeal carcinoma in Chinese PLA ... | ['Carcinoma, Squamous Cell', 'Humans', 'Laryngeal Neoplasms', 'Laryngectomy', 'Neoplasm Staging', 'Postoperative Period', 'Retrospective Studies', 'Survival Rate', 'Treatment Outcome'] | 24,364,114 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E04.580.369'], ['E01.789.625'], ['E04.614.750', 'N02.421.585.753.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genome research: fulfilling the public's expectations for knowledge and commercialization. | This article provides a historical perspective for the patenting of gene sequences and describes the fundamentals and evolution of patent law. It summarizes federal technology transfer law and policy and assesses the impacts of patenting on academic research. The patentability of gene sequences is then considered along... | ['Animals', 'Base Sequence', 'Biomedical Research', 'Biotechnology', 'DNA', 'Federal Government', 'Genome', 'Genome, Human', 'Government Regulation', 'Humans', 'Hybridomas', 'Information Dissemination', 'Patents as Topic', 'Research', 'United States'] | 1,502,557 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.770.644.145'], ['H01.158.550', 'J01.897.120'], ['D13.444.308'], ['I01.409.137', 'I01.409.418.625', 'N03.540.348.500', 'N03.540.400.750'], ['G05.360.340'], ['G05.360.340.350'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Peripheral neuropathy: a complication of systemic sclerosis. | We performed bedside testing for peripheral neuropathy in our systemic sclerosis (SSc) population to determine whether foot care guidelines should be developed for SSc. Twenty consecutive SSc patients and 20 healthy control (HC) patients were evaluated for peripheral neuropathy in both feet using the 10-g Semmes-Weinst... | ['Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Observer Variation', 'Peripheral Nervous System Diseases', 'Reproducibility of Results', 'Risk Factors', 'Scleroderma, Systemic', 'Ulcer', 'Vibration'] | 23,404,236 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['M01.060.116.630'], ['E01.354.753', 'N02.42... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dogs infected with the blood trypomastigote form of Trypanosoma cruzi display an increase expression of cytokines and chemokines plus an intense cardiac parasitism during acute infection. | The recent increase in immigration of people from areas endemic for Chagas disease (Trypanosoma cruzi) to the United States and Europe has raised concerns about the transmission via blood transfusion and organ transplants in these countries. Infection by these pathways occurs through blood trypomastigotes (BT), and the... | ['Animals', 'Chagas Disease', 'Chemokine CCL3', 'Chemokine CCL5', 'Cytokines', 'Disease Models, Animal', 'Dogs', 'Female', 'Heart', 'Host-Parasite Interactions', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-12 Subunit p40', 'Male', 'Myocardium', 'RNA, Messenger', 'Receptors, CCR5', 'Transforming Growth Factor bet... | 24,317,279 | [['B01.050'], ['C01.610.752.300.900.200', 'C01.920.625'], ['D12.644.276.374.200.110.150', 'D12.644.276.374.200.600.150', 'D12.776.467.374.200.110.150', 'D12.776.467.374.200.600.150', 'D23.125.300.110.150', 'D23.125.300.600.500', 'D23.469.200.110.150', 'D23.469.200.600.150', 'D23.529.374.200.110.150', 'D23.529.374.200.6... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Workplace violence against resident doctors in a tertiary care hospital in Delhi. | BACKGROUND: Healthcare workers particularly doctors are at high risk of being victims of verbal and physical violence perpetrated by patients or their relatives. There is a paucity of studies on work-related violence against doctors in India. We aimed to assess the exposure of workplace violence among doctors, its cons... | ['Adult', 'Communication', 'Emergency Service, Hospital', 'Female', 'Humans', 'India', 'Internship and Residency', 'Male', 'Physician-Patient Relations', 'Physicians', 'Prevalence', 'Risk Factors', 'Surveys and Questionnaires', 'Tertiary Care Centers', 'Workplace Violence'] | 28,327,484 | [['M01.060.116'], ['F01.145.209', 'L01.143'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F01.829.401.650.675', 'N05.300.660.625'], ['M01.526.485.810', 'N02.360.810'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Changes in shape, ossification and quality of bones in children with spina bifida. | Changes in the cross-sectional shape, size, bone mass and amount of unmineralised osteoid tissue were studied in 17 dissected tibiae from spina-bifida babies who died with paralysis and foot deformities and in 14 tibiae from non-spina bifida controls of matching age. In addition, 12 tibiae from young experimental rats ... | ['Animals', 'Animals, Newborn', 'Female', 'Fibula', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Muscles', 'Ossification, Heterotopic', 'Rats', 'Spinal Dysraphism', 'Tibia'] | 828,114 | [['B01.050'], ['B01.050.050.282'], ['A02.835.232.043.650.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A02.633', 'A10.690'], ['C23.550.751'], ['B01.050.150.900.649.313.992.635.505.700'], ['C10.500.680.800', 'C16.131.666.680.800'], ['A02.835.232.043.650.883']] | ['Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Environmental and social factors in rheumatoid factor epidemiology. | The effect of social and environmental conditions on the epidemiology of Rheumatoid Factor (RF) in healthy population was studied. For this purpose 2 sample of 828 subject was studied using 5 tests for RF. Our sample included: 419 randomized subjects from a quarter at the outskirts of Bologna (high rate immigration, no... | ['Adult', 'Agglutination Tests', 'Environment', 'Epidemiologic Methods', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Reference Values', 'Rheumatoid Factor', 'Rural Population', 'Socioeconomic Factors', 'Urban Population'] | 3,238,354 | [['M01.060.116'], ['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['G16.500.275', 'N06.230'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['E05.978.810'], ['D12.776.124.486.485.114.323.732', 'D12.776.124.790.651.114.323.73... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Activity of oxidative enzymes of the tricarboxylic acid cycle in the liver of rats during hypokinesia]. | The activity of oxidative enzymes of the Krebs cycle was examined in white rats during hypokinesia. On hypokinesia day 7 the cytosol activity of NAD-dependent isocitrate dehydrogenase (ICDH) increased and that of malic-enzyme decreased. On hypokinesia days 30 and 45 the activity of succinate dehydrogenase (SDH) and alp... | ['Animals', 'Citric Acid Cycle', 'Cytosol', 'Isocitrate Dehydrogenase', 'Ketoglutarate Dehydrogenase Complex', 'Liver', 'Malate Dehydrogenase', 'Male', 'Mitochondria, Liver', 'Rats', 'Restraint, Physical', 'Succinate Dehydrogenase'] | 6,843,075 | [['B01.050'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D08.811.682.047.820.475'], ['D05.500.562.468', 'D08.811.600.465', 'D08.811.682.657.350.750'], ['A03.620'], ['D08.811.682.047.820.496'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attraction of position preference by spatial attention throughout human visual cortex. | Voluntary spatial attention concentrates neural resources at the attended location. Here, we examined the effects of spatial attention on spatial position selectivity in humans. We measured population receptive fields (pRFs) using high-field functional MRI (fMRI) (7T) while subjects performed an attention-demanding tas... | ['Adult', 'Attention', 'Eye Movements', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Motion Perception', 'Photic Stimulation', 'Psychomotor Performance', 'Space Perception', 'Visual Cortex', 'Young Adult'] | 25,242,220 | [['M01.060.116'], ['F02.830.104.214'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['F02.463.593.932.567'], ['E05.723.729'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.463.593.778'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vestibular malformation in mice lacking Na-K-2Cl cotransporter 1 and expression of Na-K-2Cl cotransporter 1 in human vestibular end organs. | CONCLUSION: The Na-K-2Cl cotransporter-1 (NKCCl) may be essential for the maintenance and functioning of the vestibular morphology in mice and it is strongly expressed in human vestibular end organs.OBJECTIVE: NKCCl is a member of the cation-coupled chloride transporter which participates in salt transport and cell vol... | ['Animals', 'Biopsy, Needle', 'Gene Expression Regulation', 'Humans', 'Immunohistochemistry', 'Ion Transport', 'Membrane Transport Proteins', 'Mice', 'Mice, Knockout', 'Models, Animal', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sodium-Potassium-Chloride Symporters', 'Species Specificity', 'V... | 16,303,670 | [['B01.050'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cyanidin ameliorates the progression of osteoarthritis via the Sirt6/NF-êB axis in vitro and in vivo. | Osteoarthritis (OA) is the most prevalent form of human arthritis which is characterized by the degradation of cartilage and inflammation. As a rare Sirt6 activator, cyanidin is the major component of anthocyanins commonly found in the Mediterranean diet, and increasing evidence has shown that cyanidin exhibits anti-in... | ['Animals', 'Anthocyanins', 'Anti-Inflammatory Agents', 'Chondrocytes', 'Cyclooxygenase 2', 'Humans', 'Interleukin-1beta', 'Interleukin-6', 'Male', 'Matrix Metalloproteinase 13', 'Mice', 'Mice, Inbred C57BL', 'NF-kappa B', 'Osteoarthritis', 'Sirtuins'] | 31,464,310 | [['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D27.505.954.158'], ['A11.329.171'], ['D08.811.600.720.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute effect of cigarette smoke and nicotine on airway blood flow and airflow in healthy smokers. | Cigarette smoke contains irritants and vasoactive substances. We wanted to determine the effect of smoking a cigarette and of nasally or orally inhaled nicotine on airway blood flow (Q(aw)) and airflow in smokers. In ten healthy current smokers, Q(aw), FEV(1), and FEF(25-75) were measured before and at 5, 30, and 180 m... | ['Adult', 'Blood Pressure', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Nicotine', 'Regional Blood Flow', 'Respiratory System', 'Smoke', 'Smoking', 'Spirometry', 'Vasodilation'] | 17,111,093 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.760.570', 'D03.383.725.518'], ['G09.330.100.780'], ['A04'], ['D20.633.937'], ['F01.145.805'], ['E01.370.386.700.750'], ['G09.330.380.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rectal sensory evoked potentials: an assessment of their clinical value. | To assess abnormalities of sensory conduction in anorectal disease we have evaluated peripheral sensory perception and somatosensory evoked potentials produced by rectal stimulation in control subjects and patients with either constipation or idiopathic faecal incontinence. Evoked potentials were also recorded after po... | ['Adult', 'Case-Control Studies', 'Constipation', 'Electric Stimulation', 'Evoked Potentials, Somatosensory', 'Fecal Incontinence', 'Female', 'Humans', 'Male', 'Rectum', 'Reproducibility of Results', 'Sensation', 'Sensory Thresholds'] | 8,492,039 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.888.821.150'], ['E05.723.402'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['E05.318.370.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative evaluation of three selective media and a nonselective medium for the culture of Helicobacter pylori from gastric biopsies. | Plating on solid media is the standard technique used in most laboratories for the isolation of Helicobacter pylori from gastric biopsies. Recently, various selective media were developed for this purpose. We compared and evaluated three selective media, Skirrow's, Dent's CP, and modified Glupczynski's Brussels campylo... | ['Bacteriological Techniques', 'Biopsy', 'Culture Media', 'Evaluation Studies as Topic', 'Helicobacter pylori', 'Humans', 'Pyloric Antrum'] | 1,774,265 | [['E01.370.225.875.150', 'E05.200.875.150'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D27.720.470.305', 'E07.206'], ['E05.337', 'N05.715.360.335'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.90... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading. | Release of arachidonic acid (AA) and subsequent formation of a lipoxygenase (LOX) metabolite(s) is an obligatory signal to induce spreading of HeLa cells on a gelatin substratum (Chun and Jacobson, 1992). This study characterizes signaling pathways that follow the LOX metabolite(s) formation. Levels of diacylglycerol (... | ['Arachidonic Acid', 'Cell Adhesion', 'Diglycerides', 'Enzyme Activation', 'Feedback', 'HeLa Cells', 'Humans', 'Hydrolysis', 'Lipoxygenase', 'Phospholipases A', 'Phospholipases A2', 'Protein Kinase C'] | 8,485,318 | [['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['G04.022'], ['D10.351.303'], ['G02.111.263', 'G03.328'], ['L01.906.394.211'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['D08.811.682.690.416.583.625', 'D12.776.556.579.374.568.75... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The value of electroencephalography monitoring and analysis during anesthesia]. | Electroencephalography (EEG) records brain electrical activity at the scalp level. As a functional and non invasive witness of brain activity, EEG has long raised the interest of researchers and practitioners, notably in the domain of anesthesia. Thanks to technical advances, this complex signal can now be dissected, a... | ['Anesthesia', 'Electroencephalography', 'Humans', 'Intraoperative Neurophysiological Monitoring'] | 25,796,795 | [['E03.155'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.510.500', 'E01.370.520.596.500', 'E04.510.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Influence of loach egg- and embryo-extract on the activity of lactate dehydrogenase in the presence of insulin]. | Studies of the pig muscle lactate dehydrogenase (LDH) activity were permormed after incubating the enzyme solution with extracts of loach (Misgurnus fossilis) eggs and embryos, which were subjected to the influence of insulin hydrocortisone as well as to insulin combination with actinomycin D, cycloheximide or puromyci... | ['Animals', 'Cycloheximide', 'Dactinomycin', 'Enzyme Activation', 'Female', 'Fishes', 'Hydrocortisone', 'Insulin', 'L-Lactate Dehydrogenase', 'Muscles', 'Ovum', 'Puromycin', 'Swine', 'Tissue Extracts'] | 571,156 | [['B01.050'], ['D03.383.621.808.240'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.493'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D08.811.682.047.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-allergic activity of emodin on IgE-mediated activation in RBL-2H3 cells. | BACKGROUND: EMODIN (1,3,8-trihydroxy-6-methylanthraquinone) is a Chinese herbal anthraquinone derivative from the rhizome of rhubarb (Rheum palmatum L.) that exhibits numerous biological activities, such as antitumor, antibacterial, antiinflammatory, and immunosuppressive. In the present studies, the anti-allergic acti... | ['Animals', 'Anti-Allergic Agents', 'Calcium', 'Cell Line, Tumor', 'Emodin', 'Immunoglobulin E', 'Rats', 'Tumor Necrosis Factor-alpha', 'beta-N-Acetylhexosaminidases'] | 23,238,477 | [['B01.050'], ['D27.505.954.016'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.426.559.847.117.159.353', 'D02.806.100.353', 'D04.615.117.159.353'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['B0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictive factors of gastroduodenal toxicity in cirrhotic patients after three-dimensional conformal radiotherapy for hepatocellular carcinoma. | BACKGROUND AND PURPOSE: To identify predictive factors for the development of gastroduodenal toxicity (GDT) in cirrhotic patients treated with three-dimensional conformal radiotherapy (3D-CRT) for hepatocellular carcinoma (HCC).MATERIALS AND METHODS: We retrospectively analyzed dose-volume histograms (DVHs) and clinica... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Duodenum', 'Female', 'Gastric Mucosa', 'Humans', 'Liver Cirrhosis', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Radiotherapy, Conformal', 'Retrospective Studies'] | 19,524,314 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A03.556.124.684.124', 'A03.556.875.249'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['C04.588.274.623'... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Intrauterine necrosis in closed gastroschisis]. | INTRODUCTION: Strangulation of the intestine as the result of compression of its blood supply in a tightly closed gastroschisis defect is a very rare occurrence.CLINICAL CASES: We present the cases of two newborn patients who had extra-abdominal infarcted bowel and intra-abdominal jejunal atresia due to vascular compre... | ['Colon', 'Female', 'Gastroschisis', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Intestinal Diseases', 'Laparotomy', 'Male', 'Necrosis', 'Pregnancy', 'Pregnancy Complications', 'Radiography, Abdominal', 'Treatment Outcome'] | 15,310,450 | [['A03.556.124.526.356', 'A03.556.249.249.356'], ['C05.660.417', 'C16.131.621.417', 'C23.300.707.374.500'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C06.405.469'], ['E04.406'], ['C23.550.717'], ['G08.686.784.769'], ['C13.703'], ['E01.370.350.700... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ARHGEF9 mutations in epileptic encephalopathy/intellectual disability: toward understanding the mechanism underlying phenotypic variation. | ARHGEF9 resides on Xq11.1 and encodes collybistin, which is crucial in gephyrin clustering and GABAA receptor localization. ARHGEF9 mutations have been identified in patients with heterogeneous phenotypes, including epilepsy of variable severity and intellectual disability. However, the mechanism underlying phenotype v... | ['Adult', 'Biological Variation, Population', 'Child', 'Epilepsy', 'Female', 'Genotype', 'Humans', 'Intellectual Disability', 'Male', 'Mutation, Missense', 'Phenotype', 'Protein Domains', 'Rho Guanine Nucleotide Exchange Factors', 'Young Adult'] | 29,130,122 | [['M01.060.116'], ['G16.117'], ['M01.060.406'], ['C10.228.140.490'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['G05.365.590.650'], ['G05.695'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['D12.644.360.325... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expansion microscopy for the analysis of centrioles and cilia. | Centrioles are vital cellular structures that organise centrosomes and cilia. Due to their subresolutional size, centriole ultrastructural features have been traditionally analysed by electron microscopy. Here we present an adaptation of magnified analysis of the proteome expansion microscopy method, to be used for a r... | ['Cell Line', 'Centrioles', 'Cilia', 'Humans', 'Microscopy'] | 31,691,972 | [['A11.251.210'], ['A11.284.430.214.190.750.585.160.130', 'A11.284.430.214.190.750.820.500.500.130'], ['A11.284.180.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Spectrofluorimetric determination of tetracycline and anhydrotetracycline in serum and urine. | A spectrofluorimetric method, involving alkaline degradation and formation of a magnesium complex, is described for the determination of tetracycline (TC) and anhydrotetracycline (ATC) in their mixed solution. Tetracycline is degraded and determined in alkaline solution. This treatment of ATC produces almost no fluores... | ['Humans', 'Spectrometry, Fluorescence', 'Tetracycline', 'Tetracyclines'] | 1,443,636 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['D02.455.426.559.847.562.900.875', 'D04.615.562.900.875'], ['D02.455.426.559.847.562.900', 'D04.615.562.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Additional Screening and Treatment of Malaria During Pregnancy Provides Further Protection Against Malaria and Nonmalarial Fevers During the First Year of Life. | Background: Although consensus exists that malaria in pregnancy (MiP) increases the risk of malaria in infancy, and eventually nonmalarial fevers (NMFs), there is a lack of conclusive evidence of benefits of MiP preventive strategies in infants.Methods: In Burkina Faso, a birth cohort study was nested to a clinical tri... | ['Adult', 'Antimalarials', 'Burkina Faso', 'Cohort Studies', 'Drug Combinations', 'Female', 'Humans', 'Incidence', 'Infant', 'Malaria, Falciparum', 'Male', 'Mass Screening', 'Plasmodium falciparum', 'Pregnancy', 'Pregnancy Complications, Parasitic', 'Pyrimethamine', 'Sulfadoxine'] | 29,659,897 | [['M01.060.116'], ['D27.505.954.122.250.100.085'], ['Z01.058.290.190.245'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mesenteric lymphatic obstruction in Crohn's disease. | The lymphatic drainage of diseased and normal bowel was studied in 21 patients undergoing surgery for Crohn's disease. Mesenteric lymphatic obstruction was a consistent feature, identified in areas of small bowel macroscopically affected by Crohn's disease. This finding was also observed in some areas of apparently una... | ['Animals', 'Crohn Disease', 'Disease Models, Animal', 'Female', 'Humans', 'Lymphatic Diseases', 'Male', 'Rats'] | 7,390,055 | [['B01.050'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Role of NF-êB inhibitor in Acute Myeloid Leukemia]. | OBJECTIVE: To investigate the role of NF-êB inhibitor in occurence and development of AML.METHODS: AML and normal bone marrow samples were collected from 8 AML patients and 8 normal persons. The expression of NF-êB signaling pathway genes was detected by NF-êB PCR array. Then, AML mouse model was constructed to test th... | ['Animals', 'Apoptosis', 'Bone Marrow', 'Cell Cycle', 'Hematopoietic Stem Cells', 'Humans', 'Leukemia, Myeloid, Acute', 'Mice', 'NF-kappa B', 'Signal Transduction', 'Transcription Factor RelA', 'Tumor Necrosis Factor Ligand Superfamily Member 14'] | 28,024,466 | [['B01.050'], ['G04.146.954.035'], ['A15.382.216'], ['G04.144'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['G02.111.8... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular Diffusion in Plasma Membranes of Primary Lymphocytes Measured by Fluorescence Correlation Spectroscopy. | Fluorescence correlation spectroscopy (FCS) is a powerful technique for studying the diffusion of molecules within biological membranes with high spatial and temporal resolution. FCS can quantify the molecular concentration and diffusion coefficient of fluorescently labeled molecules in the cell membrane. This techniqu... | ['Animals', 'Cell Membrane', 'Diffusion', 'Fluorescent Dyes', 'Killer Cells, Natural', 'Membrane Proteins', 'Mice', 'Microscopy, Confocal', 'Spectrometry, Fluorescence'] | 28,190,071 | [['B01.050'], ['A11.284.149'], ['G01.202', 'G02.196'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.395', 'E05.595.395'], ['E05.196.712.516.600.676', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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