Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reduction in FSH Throughout the Menstrual Cycle After Omega-3 Fatty Acid Supplementation in Young Normal Weight but not Obese Women. | Dietary fish oil restores ovarian function in subfertile rats, which is thought to be associated with decreased transcription of follicle-stimulating hormone (FSH) â-subunit. We have previously demonstrated a reduction in early follicular serum FSH levels in normal weight but not obese women after treatment with omega-... | ['Adult', 'Dietary Supplements', 'Docosahexaenoic Acids', 'Eicosapentaenoic Acid', 'Estrogens', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Luteinizing Hormone', 'Menstrual Cycle', 'Obesity', 'Progestins', 'Young Adult'] | 30,773,100 | [['M01.060.116'], ['G07.203.300.456', 'J02.500.456'], ['D10.212.302.380.410.210', 'D10.251.355.337.250', 'D10.627.430.450.375'], ['D10.212.302.380.410.385', 'D10.251.355.255.200', 'D10.251.355.337.290', 'D10.627.430.450.390'], ['D27.505.696.399.472.277'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Studies on hemoglobinuria produced by venom from the Australian snake Tropidechis carinatus (rough-scaled snake). | Hemoglobinuria occurs in rats, but not in mice, after i.p. application of Tropidechis carinatus venom. By gel filtration on Sephadex G-75 and G-50 and chromatography on SP-Sephadex C-25 and DEAE-cellulose, a coagulant factor and a phospholipase A were isolated from the venom which in combination only, produced hemoglob... | ['Animals', 'Chromatography, Gel', 'Coagulants', 'Elapid Venoms', 'Hemoglobinuria', 'Phospholipases A', 'Rats'] | 7,164,111 | [['B01.050'], ['E05.196.181.400.250'], ['D27.505.954.502.270'], ['D20.888.850.325', 'D23.946.833.850.325'], ['C12.777.934.734.634', 'C13.351.968.934.734.634', 'C23.888.942.750.634'], ['D08.811.277.352.100.680.750'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clozapine treatment of bipolar disorder in a young adolescent. | A 13-year-old boy with a 4-year history of bipolar disorder and concomitant obsessive-compulsive disorder required four hospitalizations and two partial hospitalizations due to inadequate responses to combinations of neuroleptics and traditional treatments for bipolar disorder. The use of clozapine in combination with ... | ['Adolescent', 'Bipolar Disorder', 'Clozapine', 'Drug Interactions', 'Hallucinations', 'Humans', 'Male', 'Obsessive-Compulsive Disorder', 'Valproic Acid'] | 7,995,796 | [['M01.060.057'], ['F03.084.500'], ['D03.633.300.240.220'], ['G07.690.773.968'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.600'], ['D02.241.081.944.509.900', 'D10.251.400.895.593.900']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efficacy of clobazam as add-on therapy in patients with refractory partial epilepsy. | PURPOSE: Clobazam (CLB) has an important antiepileptic effect and is less expensive than the new antiepileptic drugs (AEDs), but still has not been considered as first-line drug in the treatment of epilepsy. We evaluated the efficacy of CLB as add-on therapy in patients with refractory partial epilepsy.METHODS: This wa... | ['Adolescent', 'Adult', 'Aged', 'Anti-Anxiety Agents', 'Anticonvulsants', 'Benzodiazepines', 'Clobazam', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Epilepsies, Partial', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Survival Analysis', 'Treatment Outcome'] | 11,440,350 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D27.505.954.427.080'], ['D03.633.100.079.080'], ['D03.633.100.079.080.165'], ['E02.319.283'], ['E02.319.310'], ['C10.228.140.490.360'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Novel and Faster Method to Obtain a Differentiated 3-Dimensional Tissue Engineered Bladder. | PURPOSE: We report what is to our knowledge a novel approach that led to the rapid development of a 3-dimensional bladder model, including a differentiated urothelium reconstructed without a period of exposure to the air-liquid interface.MATERIALS AND METHODS: Bilayered bladder constructs were produced using anchored m... | ['Cell Differentiation', 'Cells, Cultured', 'Humans', 'Time Factors', 'Tissue Engineering', 'Urinary Bladder', 'Urothelium'] | 25,758,608 | [['G04.152'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.857'], ['E05.481.500.311.500', 'J01.293.069.249.500'], ['A05.810.890'], ['A10.272.850']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode. | BACKGROUND: Bipolar disorder (BD) has been increasingly associated with abnormalities in neuroplasticity and cellular resilience. Brain Derived Neurotrophic Factor (BDNF) gene has been considered an important candidate marker for the development of bipolar disorder and this neurotrophin seems involved in intracellular ... | ['Adult', 'Biomarkers', 'Bipolar Disorder', 'Brain-Derived Neurotrophic Factor', 'Female', 'Humans', 'Male', 'Psychiatric Status Rating Scales', 'Reference Values', 'Statistics as Topic'] | 16,893,527 | [['M01.060.116'], ['D23.101'], ['F03.084.500'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.653'], ['E05.978.810'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Anomeric configuration, glycosidic linkage, and the solution conformational entropy of O-linked disaccharides. | Oligosaccharides perform a large number of biological roles, as dictated by their chemical structure and spatial arrangement. While conformational entropies are usually determined in vacuo by computer modeling, molecular recognition processes normally take place in solution. Here I show results of experiments using siz... | ['Carbohydrate Conformation', 'Disaccharides', 'Entropy', 'Glycosides'] | 12,670,236 | [['G02.111.570.820.235'], ['D09.698.629.305', 'D09.947.750'], ['G01.906.345'], ['D09.408']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MagiProbe: a novel fluorescence quenching-based oligonucleotide probe carrying a fluorophore and an intercalator (II). | MagiProbe is a fluorescence quenching-based oligonucleotide probe and applicable to homogeneous nucleic acid assays. Further advantage of this probe is its inherent ability to discriminate between matched and mismatched duplex without reliance on the difference of thermal stability. To improve discriminating ability, t... | ['Base Sequence', 'Fluorescence', 'Fluorescent Dyes', 'Heteroduplex Analysis', 'Intercalating Agents', 'Oligonucleotide Probes'] | 12,836,324 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E05.393.661.250'], ['D27.720.470.410.360'], ['D13.444.600.601', 'D27.505.259.750.600.650', 'D27.720.470.530.600.650']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Synthesis of new conformationally constrained pentasaccharides as molecular probes to investigate the biological activity of heparin. | We have synthesized three new antithrombin activating pentasaccharides displaying various sulfation patterns on the reducing end unit (H). We found that when L-iduronic acid stands in the 2S(0) conformation, the sulfate groups at positions 3 and 6 of the reducing end unit are practically devoid of influence on the acti... | ['Antithrombin III', 'Antithrombins', 'Binding Sites', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Glycoproteins', 'Heparin', 'Iduronic Acid', 'Molecular Probes', 'Molecular Sequence Data', 'Oligosaccharides', 'Structure-Activity Relationship', 'Sulfates'] | 12,765,779 | [['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['D27.505.519.389.745.800.449', 'D27.505.954.502.119.500'], ['G02.111.570.120'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D09.400.430', 'D12.776.395'], ['D09.698.373.400'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The in vitro and in vivo validation of a mobile non-contact camera-based digital imaging system for tooth colour measurement. | OBJECTIVE: To assess the reproducibility of a mobile non-contact camera-based digital imaging system (DIS) for measuring tooth colour under in vitro and in vivo conditions.METHODS: One in vitro and two in vivo studies were performed using a mobile non-contact camera-based digital imaging system. In vitro study: two ope... | ['Adolescent', 'Adult', 'Aged', 'Color', 'Colorimetry', 'Cuspid', 'Equipment Design', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Incisor', 'Male', 'Middle Aged', 'Observer Variation', 'Photography, Dental', 'Reproducibility of Results', 'Time Factors', 'Tooth'] | 18,646,365 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G01.590.540.199'], ['E05.196.922.250'], ['A14.549.167.860.200'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A14.549.167.860.425'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Materials used in drinking water distribution systems: contribution to taste-and-odor. | In order to assist drinking water utilities with identifying the possible sources and causes of taste-and-odor conditions associated with materials used in distribution systems, we evaluated information from case studies and a database from the National Sanitation Foundation (NSF), International. This database identifi... | ['Databases, Factual', 'Equipment Design', 'Materials Testing', 'Odorants', 'Reference Values', 'Sanitation', 'Taste', 'Water Supply'] | 15,237,628 | [['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.320'], ['E05.570'], ['G16.500.275.640', 'N06.230.480'], ['E05.978.810'], ['H02.229.782', 'N06.850.780.200.800', 'N06.850.860'], ['F02.830.816.724', 'G11.561.790.724'], ['J01.293.821.500']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Peri-implant osseointegration after low-level laser therapy: micro-computed tomography and resonance frequency analysis in an animal model. | The purpose of the present study is to evaluate the effects of low-level laser therapy on the osseointegration process by comparing resonance frequency analysis measurements performed at implant placement and after 30 days and micro-computed tomography images in irradiated vs nonirradiated rabbits. Fourteen male New Ze... | ['Animals', 'Dental Implantation, Endosseous', 'Disease Models, Animal', 'Lasers, Semiconductor', 'Low-Level Light Therapy', 'Male', 'Mandible', 'Osseointegration', 'Rabbits', 'Random Allocation', 'X-Ray Microtomography'] | 27,534,769 | [['B01.050'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E07.632.490.480', 'E07.710.520.480'], ['E02.594.540', 'E02.774.500'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['G11.427.213.140.570', 'G16.762.150.150.570'], ['B01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Reversible male sterility: a novel system for the production of hybrid corn. | Hybrid corn seed is traditionally produced using either mechanical/hand detasseling or cytoplasmic male sterility, or a combination of both. In recent years, the development of transgenic systems to produce hybrid seed in several crops has attracted much attention. Here we describe a transgenic mechanism for production... | ['Hybridization, Genetic', 'Phenotype', 'Plants, Genetically Modified', 'Reproduction', 'Zea mays'] | 10,645,437 | [['E05.820.150.390', 'G05.090.390'], ['G05.695'], ['B01.650.520', 'B05.620.600'], ['G08.686.784'], ['B01.650.940.800.575.912.250.822.966']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus. | Adenovirus (Ad) enters target cells by receptor-mediated endocytosis, escapes to the cytosol, and then delivers its DNA genome into the nucleus. Here we analyzed the trafficking of fluorophore-tagged viruses in HeLa and TC7 cells by time-lapse microscopy. Our results show that native or taxol-stabilized microtubules (M... | ['Adenoviruses, Human', 'Animals', 'Base Sequence', 'Cell Line', 'Cell Nucleus', 'Chlorocebus aethiops', 'Cytosol', 'DNA Primers', 'Dynactin Complex', 'Dyneins', 'Fluorescent Dyes', 'Green Fluorescent Proteins', 'HeLa Cells', 'Humans', 'Luminescent Proteins', 'Microscopy, Fluorescence', 'Microtubule-Associated Proteins... | 10,037,788 | [['B04.280.030.500.350'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D13.695.578.424.450.275... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A comparison of mental health of multiple sclerosis patients with silver/mercury dental fillings and those with fillings removed. | In this study was compared the mental health status of 47 multiple sclerosis patients with silver/mercury tooth fillings (amalgams) to that of 50 patients with their fillings removed. On the Beck Depression Inventory the multiple sclerosis subjects with amalgams suffered significantly more depression while their scores... | ['Adaptation, Psychological', 'Adult', 'Dental Amalgam', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mercury Poisoning', 'Multiple Sclerosis', 'Neuropsychological Tests', 'Personality Inventory', 'Risk Factors', 'Sick Role', 'Substance-Related Disorders'] | 1,496,084 | [['F01.058'], ['M01.060.116'], ['D25.339.208.291', 'J01.637.051.339.208.291'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.723.522.875'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F04.711.513'], ... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Modulating estrogen receptor-related receptor-alpha activity inhibits cell proliferation. | High expression of the estrogen receptor-related receptor (ERR)-alpha in human tumors is correlated to a poor prognosis, suggesting an involvement of the receptor in cell proliferation. In this study, we show that a synthetic compound (XCT790) that modulates the activity of ERRalpha reduces the proliferation of various... | ['Animals', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Down-Regulation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice', 'Neoplasms', 'Nitriles', 'Receptors, Estrogen', 'Thiazoles'] | 19,546,226 | [['B01.050'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04'], ['D02.626'], ['D12.776.826.750.350', 'D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppressive effect of prolactin on oestrogen-induced secretion of LH by sequentially perifused rat hypothalamus-pituitary. | The effect of prolactin (Prl) on oestrogen-induced gonadotrophin secretion was examined in vitro in a sequential double chamber perfusion system. As control groups, mediobasal hypothalamus (MBH)-pituitary pairs or pituitaries without the MBHs were perifused with Medium 199. As an experimental group, MBH-pituitary pairs... | ['Animals', 'Culture Media', 'Estradiol', 'Female', 'Hypothalamo-Hypophyseal System', 'Luteinizing Hormone', 'Perfusion', 'Prolactin', 'Rats', 'Rats, Inbred Strains'] | 3,969,813 | [['B01.050'], ['D27.720.470.305', 'E07.206'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['E05.680'], ['D06.472.699.32... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationships between wheelchair skills, wheelchair mobility and level of injury in individuals with spinal cord injury. | STUDY DESIGN: Cross-sectional.OBJECTIVES: To describe the manual wheelchair (MWC) skill profiles of experienced MWC users with spinal cord injury and their wheeled mobility (distance and speed) while considering their level of injury and age.SETTING: Rehabilitation centers, participant's home and the community.METHODS:... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Exercise Tolerance', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motor Skills', 'Paraplegia', 'Spinal Cord Injuries', 'Trauma Severity Indices', 'Wheelchairs', 'Young Adult'] | 21,931,330 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.680.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808.260'], ['C10.597.622.669', 'C23.888.592.636.637'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of thalamocortical and other synaptic inputs to dendrites of two non-spiny neurons in a single barrel of mouse SmI cortex. | A Golgi impregnated, non-spiny multipolar cell whose soma occurred in layer V of the region of mouse SmI cortex containing the posteromedial barrel subfield (PMBSF) (Woolsey and Van der Loos, '70) was gold-toned and deimpregnated (Fairen et al., '77). Two of its dendrites, contained within a single PMBSF barrel, were s... | ['Animals', 'Brain Mapping', 'Dendrites', 'Mice', 'Microscopy, Electron', 'Neural Pathways', 'Neurons', 'Somatosensory Cortex', 'Synapses', 'Thalamic Nuclei'] | 7,251,926 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.612'], ['A08.675', 'A11.671'], ['A08.186.211.200.885.287.500.670.675', 'A08.186.211.200.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. | The biochemical basis for the regulation of fibre-type determination in skeletal muscle is not well understood. In addition to the expression of particular myofibrillar proteins, type I (slow-twitch) fibres are much higher in mitochondrial content and are more dependent on oxidative metabolism than type II (fast-twitch... | ['Animals', 'Cell Line', 'Creatine Kinase', 'Creatine Kinase, MM Form', 'DNA-Binding Proteins', 'Electric Stimulation', 'Isoenzymes', 'MEF2 Transcription Factors', 'Mice', 'Mice, Transgenic', 'Muscle Fatigue', 'Muscle Fibers, Slow-Twitch', 'Muscle, Skeletal', 'Myogenic Regulatory Factors', 'Myoglobin', 'Promoter Region... | 12,181,572 | [['B01.050'], ['A11.251.210'], ['D08.811.913.696.640.150'], ['D08.811.913.696.640.150.875'], ['D12.776.260'], ['E05.723.402'], ['D08.811.348', 'D12.776.800.300'], ['D12.776.210.500.570.294', 'D12.776.260.103.750.294', 'D12.776.260.400.249.624', 'D12.776.930.125.750.294', 'D12.776.930.397.700'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeted metabolome analysis of the dog brain exposed to PCBs suggests inhibition of oxidative phosphorylation by hydroxylated PCBs. | Canis lupus familiaris (domestic dog) possess a high capacity to metabolize higher-chlorinated polychlorinated biphenyls (PCBs) to thyroid hormone (TH)-like hydroxylated PCB metabolites (OH-PCBs). As a result, the brain could be at high risk of toxicity caused by OH-PCBs. To evaluate the effect of OH-PCBs on dog brain,... | ['Adenosine Triphosphate', 'Animals', 'Brain Chemistry', 'Dogs', 'Electron Transport Chain Complex Proteins', 'Environmental Pollutants', 'Hydroxylation', 'Male', 'Metabolome', 'Neurotoxins', 'Oxidative Phosphorylation', 'Polychlorinated Biphenyls', 'Reactive Oxygen Species', 'Thyroid Hormones', 'Urea'] | 31,195,005 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G02.111.150', 'G03.185'], ['B01.050.150.900.649.313.750.250.216.200'], ['D08.811.600.250', 'D12.776.543.277'], ['D27.888.284'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['G03.500'], ['D27.888.569.504'], ['G02.111.665.550', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alcohol and coronary artery calcium prevalence, incidence, and progression: results from the Multi-Ethnic Study of Atherosclerosis (MESA). | BACKGROUND: Alcohol use has been consistently found to have a J-shaped association with coronary heart disease, with moderate drinkers exhibiting a decreased risk compared with both heavy drinkers and nondrinkers. However, results of studies of the association between alcohol use and subclinical coronary artery disease... | ['Aged', 'Aged, 80 and over', 'Alcohol Drinking', 'Calcinosis', 'Cohort Studies', 'Coronary Artery Disease', 'Coronary Vessels', 'Disease Progression', 'Ethnic Groups', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prevalence', 'Prospective Studies', 'Risk Factors', 'United States'] | 19,064,520 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.145.317.269'], ['C18.452.174.130'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['C23.550.291.656'], ['M01.686.754', 'N01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Feasibility of two low-cost organic substrates for inducing denitrification in artificial recharge ponds: Batch and flow-through experiments. | Anaerobic batch and flow-through experiments were performed to assess the capacity of two organic substrates to promote denitrification of nitrate-contaminated groundwater within managed artificial recharge systems (MAR) in arid or semi-arid regions. Denitrification in MAR systems can be achieved through artificial rec... | ['Algeria', 'Ammonium Compounds', 'Arecaceae', 'Chemical Fractionation', 'Denitrification', 'Environmental Monitoring', 'Groundwater', 'Nitrates', 'Nitrogen Isotopes', 'Oxidation-Reduction', 'Oxygen Isotopes', 'Plant Leaves', 'Ponds', 'Spain', 'Sulfates', 'Water Pollutants, Chemical', 'Water Purification'] | 28,131,436 | [['Z01.058.266.104'], ['D01.625.062'], ['B01.650.940.800.575.912.250.093'], ['E05.196.155'], ['G02.111.587.250', 'G02.607.560.250', 'G16.500.768.249'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.355'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.268.604.500', 'D01.362.625.500', 'D01.496.586'... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Multiple integrin ligands provide a highly adhesive and osteoinductive surface that improves selective cell retention technology. | Among various bone tissue engineering strategies, selective cell retention (SCR) technology has been used as a practical clinical method for bone graft manufacturing in real time. The more mesenchymal stem cells (MSCs) are retained, the better the osteoinductive microenvironment provided by the scaffold, which in turn ... | ['Adult', 'Amino Acid Sequence', 'Animals', 'Bone Marrow Cells', 'Bone Matrix', 'Cell Adhesion', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Collagen', 'Humans', 'Implants, Experimental', 'Integrins', 'Ligands', 'Male', 'Mesenchymal Stem Cells', 'Mice', 'Osseointegration', 'Osteogenesis', 'Peptide... | 30,557,698 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.148', 'A15.378.316'], ['A10.165.265.166'], ['G04.022'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.340'], ['D12.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Carrots, carotene and seeing in the dark. | Should older people eat more carrots, or at least increase their carotene intake to prevent loss of night vision? Participants in the Blue Mountains Eye Study were asked about their ability to see in the dark. Nutrient and food intake were estimated from a food frequency questionnaire. Associations between self-reporte... | ['Aged', 'Aged, 80 and over', 'Darkness', 'Daucus carota', 'Diet', 'Female', 'Humans', 'Male', 'Middle Aged', 'Vision, Ocular', 'Vitamin A', 'beta Carotene'] | 10,484,191 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G01.590.540.233'], ['B01.650.940.800.575.912.250.075.278'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935'], ['D02.455.326.271.665.202.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mitochondrial DNA polymorphism in the French population. | One hundred unrelated individuals of French origin were screened for mtDNA variation as restriction fragment length polymorphisms (RFLPs) with the restriction enzymes HpaI, BamHI, HaeII, MspI, AvaII and HincII. Twenty enzyme morphs were detected, four of which (AvaII-37Fr, -38Fr, HincII-18Fr and -19Fr) are new. Of the ... | ['DNA Restriction Enzymes', 'DNA, Mitochondrial', 'Europe', 'European Continental Ancestry Group', 'France', 'Genetic Variation', 'Humans', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length'] | 10,392,292 | [['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.283.225'], ['Z01.542'], ['M01.686.508.400'], ['Z01.542.286'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795'], ['G05.365.795.595']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Negative Beliefs about Voices in Patients with Borderline Personality Disorder Are Associated with Distress: A Plea for Cognitive-Behavioural Therapy? | BACKGROUND: Auditory verbal hallucinations (AVH) are experienced by 21-54% of patients diagnosed with a borderline personality disorder (BPD), and ensuing distress is often high. Little is known about the beliefs these patients foster about their voices, and the influence thereof on distress and need for hospitalisatio... | ['Adult', 'Borderline Personality Disorder', 'Cognitive Behavioral Therapy', 'Cross-Sectional Studies', 'Female', 'Hallucinations', 'Humans', 'Male', 'Psychotic Disorders'] | 28,738,347 | [['M01.060.116'], ['F03.675.100'], ['F04.754.137.350'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.700.675']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Survey of the prevalence and methodology of quality assurance for B-mode ultrasound image quality among veterinary sonographers. | Image quality in B-mode ultrasound is important as it reflects the diagnostic accuracy and diagnostic information provided during clinical scanning. Quality assurance programs for B-mode ultrasound systems/components are comprised of initial quality acceptance testing and subsequent regularly scheduled quality control ... | ['Animal Technicians', 'Cross-Sectional Studies', 'Prospective Studies', 'Quality Control', 'Ultrasonography', 'Veterinarians'] | 29,528,172 | [['M01.526.485.067.040', 'N02.360.067.040'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['J01.897.608'], ['E01.370.350.850'], ['M01.526.485.905', 'N02.360.905']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Oral Mucosa Model for Electrochemotherapy Treatment of Dog Mouth Cancer: Ex Vivo, In Silico, and In Vivo Experiments. | Electrochemotherapy (EQT) is a local cancer treatment well established to cutaneous and subcutaneous tumors. Electric fields are applied to biological tissue in order to improve membrane permeability for cytotoxic drugs. This phenomenon is called electroporation or electropermeabilization. Studies have reported that ti... | ['Animals', 'Computer Simulation', 'Dog Diseases', 'Dogs', 'Electric Conductivity', 'Electrochemotherapy', 'Electrodes', 'Electroporation', 'Equipment Design', 'Male', 'Melanoma', 'Models, Biological', 'Mouth Mucosa', 'Mouth Neoplasms', 'Rats, Wistar'] | 29,027,689 | [['B01.050'], ['L01.224.160'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.358.500.249.277'], ['E02.319.341', 'E05.200.500.454.500', 'E05.242.448.500', 'E05.301.500.500'], ['E07.305.250'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['E05.320'], ['C04.557.465.625.650.510', 'C04.557.580.625.65... | ['Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Spectrum of corrosive esophageal injury after intentional paraquat ingestion. | INTRODUCTION: This is an observational study that examines the clinical features, the degrees of esophageal injury, physiological markers, and clinical outcomes after paraquat ingestion and seeks to determine what association, if any, may exist between these findings.METHODS: The study included 16 of 1410 paraquat subj... | ['Adult', 'Burns, Chemical', 'Cohort Studies', 'Emergency Service, Hospital', 'Endoscopy', 'Esophagus', 'Female', 'Herbicides', 'Humans', 'Male', 'Middle Aged', 'Paraquat', 'Retrospective Studies', 'Young Adult'] | 20,637,392 | [['M01.060.116'], ['C26.200.156'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E01.370.388.250', 'E04.502.250'], ['A03.556.875.500'], ['D27.720.031.700.366', 'D27.888.723.366'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Malignant effusion of chromophobe renal-cell carcinoma: cytological and immunohistochemical findings. | Malignant effusions because of renal-cell carcinoma (RCC) are an unusual event and occur in patients with papillary and clear cell tumors. We have studied a 65-year-old man who underwent right renal tumorectomy, diagnosed as chromophobe RCC (pT1). After 16 months, the patient presented cough and fever. Positron emissio... | ['Aged', 'Carcinoma, Renal Cell', 'Humans', 'Immunohistochemistry', 'Kidney Neoplasms', 'Male', 'Pleural Effusion, Malignant'] | 22,180,239 | [['M01.060.116.100'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.55... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Height Error Correction for Shoe-Mounted Inertial Sensors Exploiting Foot Dynamics. | Shoe-mounted inertial sensors are widespread deployed in satellite-denied scenarios because of the possibility to re-calibrate stepwise the estimated position. These re-calibrations, known as zero-velocity corrections, prevent an accumulated positioning error growth over time caused by the noise of current medium- and ... | ['Algorithms', 'Calibration', 'Foot', 'Humans', 'Shoes', 'Walking'] | 29,547,581 | [['G17.035', 'L01.224.050'], ['E05.978.155'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.215.800'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450.642.845.940']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 |
Expression and topography of integrins and basement membrane proteins in epidermal carcinomas: basal but not squamous cell carcinomas display loss of alpha 6 beta 4 and BM-600/nicein. | The expression and topography of some integrins and basement membrane proteins in cutaneous basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) have been studied by immunohistochemistry and Western blotting. It has been shown that the typical cell-to-cell distribution of alpha 2 beta 1 and alpha 3 beta 1 f... | ['Adenocarcinoma', 'Antibodies, Monoclonal', 'Basement Membrane', 'Blotting, Western', 'Carcinoma, Basal Cell', 'Carcinoma, Squamous Cell', 'Cell Adhesion Molecules', 'Humans', 'Immunoenzyme Techniques', 'Integrins', 'Pancreatic Neoplasms', 'Tumor Cells, Cultured'] | 8,370,973 | [['C04.557.470.200.025'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A10.272.220', 'A10.615.179'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.557.470.200.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Home apnea monitoring: mothers' mood states, family functioning, and support systems. | Home apnea monitoring has been used increasingly for infants with or at high risk for apnea. This study examined mood states, perceived family functioning, and perceived support systems of mothers with infants on home apnea monitors from the first week on the monitor through three months after discharge. It also compar... | ['Adult', 'Affect', 'Apnea', 'Community Health Nursing', 'Counseling', 'Family', 'Female', 'Home Care Services', 'Humans', 'Monitoring, Physiologic', 'Mothers', 'Social Support', 'Stress, Psychological', 'Surveys and Questionnaires'] | 1,946,149 | [['M01.060.116'], ['F01.470.047'], ['C08.618.085', 'C23.888.852.130'], ['H02.478.676.150', 'N02.421.143.150'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F01.829.263', 'I01.880.853.150'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of chronic heat and cold stressors on plasma immunoglobulin and mitogen-induced blastogenesis in calves. | Fifty-six Holstein calves were used to investigate effects of heat and cold stressors on mitogen-induced blastogenesis of isolated peripheral blood mononuclear cells and immunoglobulins G1 and M in blood plasma. Calves were exposed to constant hot (35 degrees C), constant cold (-5 degrees C), or thermoneutral (23 degr... | ['Animals', 'Cattle', 'Cold Temperature', 'Concanavalin A', 'Hot Temperature', 'Immunoglobulin G', 'Immunoglobulin M', 'Immunoglobulins', 'Lymphocyte Activation', 'Male', 'Mitogens', 'Phytohemagglutinins', 'Stress, Physiological'] | 7,142,529 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Robust joint entropy regularization of limited view transmission tomography using Gaussian approximations to the joint histogram. | Information theoretic measures to incorporate anatomical priors have been explored in the field of emission tomography, but not in transmission tomography. In this work, we apply the joint entropy prior to the case of limited angle transmission tomography. Due to the data insufficiency problem, the joint entropy prior ... | ['Algorithms', 'Computer Simulation', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Models, Biological', 'Models, Statistical', 'Normal Distribution', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, X-... | 19,694,300 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Pleiotropy analysis of quantitative traits at gene level by multivariate functional linear models. | In genetics, pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. A common approach is to analyze the phenotypic traits separately using univariate analyses and combine the test results through multiple comparisons. This approach may lead to low power. Multivariate functional linear m... | ['Cohort Studies', 'Genetic Markers', 'Genetic Pleiotropy', 'Genetic Variation', 'Genome, Human', 'Humans', 'Linear Models', 'Models, Genetic', 'Phenotype', 'Quantitative Trait Loci', 'Software'] | 25,809,955 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D23.101.387', 'G05.695.450'], ['G05.420.556', 'G05.695.550'], ['G05.365'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Hereditary progressive atrioventricular conduction defect. | New data on genetics, including an extensive pedigree and certain aspects of natural history, have been compiled on Family S, which is characterized by a hereditary progressive atrioventricular (A-V) conduction defect. Concordance analysis of heart block in affected parents and their offspring suggests as a working hyp... | ['Adolescent', 'Atrioventricular Node', 'Child', 'Female', 'Genes, Dominant', 'Heart Block', 'Heart Conduction System', 'Humans', 'Male', 'Pedigree', 'Risk', 'Sex Factors'] | 1,166,834 | [['M01.060.057'], ['A07.541.409.147'], ['M01.060.406'], ['G05.360.340.024.340.240', 'G05.420.320'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.673'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis. | The common acute lymphoblastic leukemia antigen (CALLA) is a 749-amino acid type II integral membrane protein expressed by most acute lymphoblastic leukemias, certain other lymphoid malignancies with an immature phenotype, and normal lymphoid progenitors. A computer search against the most recent GenBank release (no. 5... | ['Animals', 'Antigens, Differentiation', 'Antigens, Neoplasm', 'Cell Line', 'DNA, Neoplasm', 'Glycopeptides', 'Humans', 'Mice', 'Neprilysin', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Restriction Mapping', 'Transfection'] | 2,521,388 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['D23.050.285'], ['A11.251.210'], ['D13.444.308.425'], ['D09.400.420', 'D12.644.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.277.656.300.480.600', 'D08.811.277.656.675.374.600', 'D23.050.285.550', 'D23.10... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Angioarchitectural structure and functional distributive pattern of the filiform papillae on the meso-dorsal surface of the rabbit tongue. | The angioarchitectural classification and distributive patterns were investigated in the filiform papillae (FiP) on the meso-dorsal surface of the rabbit tongue by using microvascular cast specimens (MVCS) and the scanning electron microscope (SEM). The author examined the microvascular network structures, which consis... | ['Animals', 'Microcirculation', 'Microscopy, Electron, Scanning', 'Models, Structural', 'Rabbits', 'Tongue'] | 9,862,035 | [['B01.050'], ['G09.330.100.645'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['B01.050.150.900.649.313.968.700'], ['A03.556.500.885', 'A14.549.885']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Prospective evaluation of lactose malabsorption by lactose hydrogen breath test in individuals infected with Entamoeba histolytica and passing cysts. | The aim of the present prospective study was to detect lactose malabsorption in subjects in northern India infected with Entamoeba histolytica and passing cysts. The study group included forty-one patients with E. histolytica cysts in at least one of three consecutive faecal samples. Lactose malabsorption was detected ... | ['Adult', 'Breath Tests', 'Cysts', 'Entamoebiasis', 'Feces', 'Female', 'Humans', 'Lactose Intolerance', 'Male', 'Middle Aged', 'Prospective Studies'] | 15,333,150 | [['M01.060.116'], ['E01.370.100'], ['C04.182', 'C23.300.306'], ['C01.610.752.049.407'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.637.506', 'C16.320.565.202.589', 'C18.452.603.506', 'C18.452.648.202.589'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Liposomes Coloaded with Elacridar and Tariquidar To Modulate the P-Glycoprotein at the Blood-Brain Barrier. | This study prepared three liposomal formulations coloaded with elacridar and tariquidar to overcome the P-glycoprotein-mediated efflux at the blood-brain barrier. Their pharmacokinetics, brain distribution, and impact on the model P-glycoprotein substrate, loperamide, were compared to those for the coadministration of ... | ['ATP Binding Cassette Transporter, Subfamily B', 'Acridines', 'Animals', 'Antidiarrheals', 'Biological Transport', 'Blood-Brain Barrier', 'Brain', 'Chromatography, Liquid', 'Dose-Response Relationship, Drug', 'Drug Therapy, Combination', 'Gene Expression Regulation', 'Liposomes', 'Loperamide', 'Male', 'Quinolines', 'R... | 26,390,138 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['D03.633.300.046'], ['B01.050'], ['D27.505.954.483.161'], ['G03.143'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['E05.196.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The sources of convergence between measures of apathy and depression. | Apathy and depression are discriminable but related dimensions of behavior. The purpose of this study was to evaluate the source of the overlap between measures of apathy and depression. We evaluated the intercorrelations between the Apathy Evaluation Scale (AES) and the Hamilton Rating Scale for Depression (HamD) in 1... | ['Aged', 'Alzheimer Disease', 'Arousal', 'Cerebrovascular Disorders', 'Dementia, Multi-Infarct', 'Depression', 'Depressive Disorder', 'Dominance, Cerebral', 'Female', 'Humans', 'Male', 'Motivation', 'Personality Inventory', 'Psychometrics', 'Reference Values'] | 8,326,082 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F02.830.104', 'G11.561.035'], ['C10.228.140.300', 'C14.907.253'], ['C10.228.140.300.150.477.200.199', 'C10.228.140.300.400.408', 'C10.228.140.300.775.200.200.199', 'C10.228.140.380.230.250', 'C14.907.253.092.477.200.199', 'C14.907.25... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
V-cluster algorithm: a new algorithm for clustering molecules based upon numeric data. | Clustering molecules based on numeric data such as, gene-expression data, physiochemical properties, or theoretical data is very important in drug discovery and other life sciences. Most approaches use hierarchical clustering algorithms, non-hierarchical algorithms (for examples, K-mean and K-nearest neighbor), and oth... | ['Algorithms', 'Cluster Analysis', 'Gene Expression Profiling', 'Models, Biological', 'Models, Theoretical', 'Pattern Recognition, Automated'] | 16,896,541 | [['G17.035', 'L01.224.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.393.332'], ['E05.599.395'], ['E05.599'], ['L01.399.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Determination of the enterotoxigenicity of conditionally pathogenic microorganisms using the method of suppressing the dehydrogenase activity of the UV mutant Staphylococcus aureus 209 P]. | The S. aureus 209P UF mutant dehydrogenase activity suppression method was used for detection of enterotoxin of Enterobacteriaceae opportunistic bacteria. Comparison of V. cholerae non 01, E coli and K. pneumonia toxigenic and nontoxigenic strains, neutralization test with antitoxic anticholera serum, comparative study... | ['Bacteriological Techniques', 'Enterobacteriaceae', 'Enterotoxins'] | 1,699,048 | [['E01.370.225.875.150', 'E05.200.875.150'], ['B03.440.450.425', 'B03.660.250.150'], ['D23.946.330']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new biomedical sensor for measuring PCO2. | Measuring PCO2 (partial pressure of carbon dioxide) in an organ can enable early detection of ischemia. However, there are few clinical applicable solutions for measuring PCO2. Based upon the requirement for clinical applications, a conductivity based PCO2 sensor is proposed. A conductivity based PCO2 sensor measures c... | ['Biomedical Technology', 'Biosensing Techniques', 'Carbon Dioxide', 'Partial Pressure'] | 15,132,308 | [['J01.897.120.050'], ['E05.601.043'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G01.374.715.714']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy. | YiiP is a dimeric Zn(2+)/H(+) antiporter from Escherichia coli belonging to the cation diffusion facilitator family. We used cryoelectron microscopy to determine a 13-? resolution structure of a YiiP homolog from Shewanella oneidensis within a lipid bilayer in the absence of Zn(2+). Starting from the X-ray structure in... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Cation Transport Proteins', 'Cryoelectron Microscopy', 'Crystallography, X-Ray', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Molecular Sequence Data', 'Protein Conformation', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Shewanella', 'Zinc'] | 23,341,604 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['E05.196.309.742.225'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['L01.453.245.667'], ['G02.111.570.820.709'], ['D12.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The mucosal collar in hypospadias surgery. | Formation of a mucosal collar from the inner surface of the prepuce offers the surgeon who performs hypospadias repairs the opportunity to create a cosmetically normal-appearing phallus. This technique results in transposition of mucosal membrane type of tissue to the subglandular area to complete the normal repair. | ['Humans', 'Hypospadias', 'Infant', 'Male', 'Penis', 'Surgery, Plastic'] | 3,795,371 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.939.516'], ['M01.060.703'], ['A05.360.444.492'], ['H02.403.810.788']] | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Diagnosis of obstructive level in pharynx with obstructive sleep apnea hypopnea syndrome with multiple detector-row spiral CT]. | OBJECTIVE: To evaluate the diagnostic significance of multiple detector-row spiral CT(MSCT) in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).METHOD: Sixty-seven patients with OSAHS and 40 volunteers were scanned. The CT imagings from the nasopharyngeal floor to the glottis obtained. The relevant dimen... | ['Adult', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pharynx', 'Sleep Apnea, Obstructive', 'Tomography, Spiral Computed'] | 18,839,879 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A03.556.750', 'A04.623', 'A14.724'], ['C08.618.085.852.850', 'C10.886.425.800.750.850'], ['E01.370.350.350.810.800', 'E01.370.350.600.350.700.810.800',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypnotherapy and cognitive behaviour therapy of acute stress disorder: a 3-year follow-up. | The long-term benefits of cognitive behaviour therapy (CBT) for trauma survivors with acute stress disorder were investigated by assessing patients 3 years after treatment. Civilian trauma survivors (n=87) were randomly allocated to six sessions of CBT, CBT combined with hypnosis, or supportive counselling (SC), 69 com... | ['Adolescent', 'Adult', 'Cognitive Behavioral Therapy', 'Combined Modality Therapy', 'Counseling', 'Follow-Up Studies', 'Humans', 'Hypnosis', 'Middle Aged', 'Stress Disorders, Traumatic, Acute', 'Treatment Outcome'] | 16,368,074 | [['M01.060.057'], ['M01.060.116'], ['F04.754.137.350'], ['E02.186'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.217', 'F04.754.424'], ['M01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unicortical PEEK inset locking fixation for metacarpal fractures: a biomechanical study. | PURPOSE: There are numerous constructs employed in the treatment of metacarpal fractures with varying degrees of success. While plate fixation commonly involves dorsal application of a bicortical non-locking plate, there has been recent exploration of other fixation options including unicortical locked plating. The pur... | ['Animals', 'Biomechanical Phenomena', 'Bone Plates', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Humans', 'Metacarpal Bones', 'Swine'] | 24,121,825 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E04.555.300.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.319.550'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of the administration of a single dose of nateglinide on insulin secretion at two different concentrations of glucose in healthy individuals. | BACKGROUND: Nateglinide is a D-phenylalanine derivative that stimulates fast insulin secretion with a short activity span. It has been suggested that the hypoglycemic effect of nateglinide is related to the glucose concentration, an aspect that still has not been completely evaluated in human beings.OBJECTIVE: The aim ... | ['Adult', 'Blood Glucose', 'Body Mass Index', 'Cross-Over Studies', 'Cyclohexanes', 'Double-Blind Method', 'Female', 'Humans', 'Hyperglycemia', 'Hyperinsulinism', 'Hypoglycemic Agents', 'Insulin', 'Insulin Secretion', 'Male', 'Nateglinide', 'Phenylalanine', 'Placebos'] | 16,260,353 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D02.455.426.392.368.367'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility: A STROBE-Compliant Observational Study. | MicroRNAs (miRNAs) play an important role as regulators of tumor suppressors and oncogenes in cancer-related processes. Single nucleotide polymorphisms (SNPs) in miRNAs have been shown to be relevant to various different cancers, including breast cancer (BC). The aim of this study was to estimate the associations betwe... | ['Adult', 'Asian Continental Ancestry Group', 'Breast Neoplasms', 'Case-Control Studies', 'China', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'MicroRNAs', 'Middle Aged', 'Polymorphism, Single Nucleotide'] | 26,886,638 | [['M01.060.116'], ['M01.686.508.200'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.252.474.164'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The Neuro-Mental Index. An addition to the Barthel Index for detection of impairments in basic psychological-mental diemsnions in neurorehabilitation]. | The Barthel Index (BI) is the most commonly used scale for assessing impairment of activities of daily living (ADL). For a global view of patients' abilities and the care needed in everyday neurorehabilitation practice, additional information about basic psychological and cognitive functions is essential. We therefore ... | ['Activities of Daily Living', 'Adult', 'Aged', 'Cognition Disorders', 'Disability Evaluation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Neuropsychological Tests', 'Psychometrics', 'Reproducibility of Results'] | 11,139,992 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['F03.615.250'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10'], ['F04.711.513'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
mTM-align: a server for fast protein structure database search and multiple protein structure alignment. | With the rapid increase of the number of protein structures in the Protein Data Bank, it becomes urgent to develop algorithms for efficient protein structure comparisons. In this article, we present the mTM-align server, which consists of two closely related modules: one for structure database search and the other for ... | ['Algorithms', 'Amino Acid Sequence', 'Benchmarking', 'Databases as Topic', 'Databases, Protein', 'Humans', 'Internet', 'Models, Molecular', 'Protein Structure, Secondary', 'Proteins', 'Software', 'Structural Homology, Protein', 'Time Factors'] | 29,788,129 | [['G17.035', 'L01.224.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['L01.313.500.750.300.188', 'L01.470.750'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Substrate relay in an Hsp70-cochaperone cascade safeguards tail-anchored membrane protein targeting. | Membrane proteins are aggregation-prone in aqueous environments, and their biogenesis poses acute challenges to cellular protein homeostasis. How the chaperone network effectively protects integral membrane proteins during their post-translational targeting is not well understood. Here, biochemical reconstitutions show... | ['Adenosine Triphosphatases', 'Carrier Proteins', 'Endoplasmic Reticulum', 'Guanine Nucleotide Exchange Factors', 'HSP70 Heat-Shock Proteins', 'Membrane Proteins', 'Protein Transport', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 29,973,361 | [['D08.811.277.040.025'], ['D12.776.157'], ['A11.284.430.214.190.875.248'], ['D12.644.360.325.300', 'D12.776.476.325.300'], ['D12.776.580.216.375'], ['D12.776.543'], ['G03.143.700'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of tadalafil on platelets and endothelium in patients with erectile dysfunction and cardiovascular risk factors: a pilot study. | Activation of endothelial cells and platelets is an initial step toward the development of cardiovascular disease. Erectile dysfunction (ED) may be an early manifestation of endotheliopathy. We evaluated the effects of tadalafil on cyclic nucleotides (cGMP and cAMP) and soluble adhesion molecules (E- and P-selectin [ES... | ['Analysis of Variance', 'Blood Platelets', 'Carbolines', 'Cyclic AMP', 'Cyclic GMP', 'Dyslipidemias', 'E-Selectin', 'Endothelium, Vascular', 'Erectile Dysfunction', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Nitric Oxide', 'P-Selectin', 'Phosphodiesterase Inhibitors', 'Pilot Projects', 'Risk Factors', 'Smoking'... | 20,395,237 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A11.118.188', 'A15.145.229.188'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Generalization of distribution--free confidence intervals for bioavailability ratios. | The confidence interval approach to bioavailability assessment depends first on selection of the confidence level, usually 95%, and then determination of the confidence limits for the expected bioavailability ratio AUC(Test)/AUC(Reference). In practice, however, it is sometimes of greater interest to know the probabili... | ['Biological Availability', 'Delayed-Action Preparations', 'Digoxin', 'Food', 'Humans', 'Models, Biological', 'Reference Values', 'Statistics as Topic', 'Theophylline'] | 3,987,790 | [['G03.787.151', 'G07.690.725.129'], ['D26.255.210', 'E02.319.300.253'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.436'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.978.810'], ['E05.318.740', 'H01.548.832', 'N05.715.360.7... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Foetal hepatic calcification. | Thirty-three cases of 1,500 spontaneously-aborted foetuses showed hepatic calcifications. The exact location of these calcifications were confirmed by contrast studies, anatomic dissection, and further histology when necessary. Of them, 18 were calcified hepatic vein thrombi (CHVT), 12 were calcified portal vein thromb... | ['Abortion, Spontaneous', 'Budd-Chiari Syndrome', 'Calcinosis', 'Congenital Abnormalities', 'Contraceptives, Oral', 'Female', 'Fetal Diseases', 'Humans', 'Liver', 'Liver Diseases', 'Maternal Age', 'Parity', 'Portal Vein', 'Pregnancy', 'Radiography', 'Thrombosis'] | 2,216,588 | [['C13.703.039', 'G08.686.784.769.496.125'], ['C06.552.347', 'C14.907.355.830.925.275'], ['C18.452.174.130'], ['C16.131'], ['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C06.552'], ['G08.686.560', 'N05.715.350.0... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Epiphyseal distraction for preservation of epiphysis of osteosarcoma in children]. | OBJECTIVE: To investigate the feasibility of the preservation of the epiphysis and joint function of the distal femur in children with osteosarcoma with epiphyseal distraction by external fixator.METHODS: Between July 2007 and May 2011, 6 children with osteoblastic osteosarcoma of the distal femur underwent epiphyseal ... | ['Adolescent', 'Bone Neoplasms', 'Bone Transplantation', 'Child', 'Epiphyses', 'External Fixators', 'Female', 'Femur', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Neoplasm Staging', 'Osteosarcoma', 'Retrospective Studies', 'Transplantation, Homologous', 'Treatment Outcome'] | 23,230,659 | [['M01.060.057'], ['C04.588.149', 'C05.116.231'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['M01.060.406'], ['A02.835.232.251'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['A02.835.232.043.150'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['C04.557.450... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Electromyographic changes in automechanics with increased heavy metal levels. | Twenty automechanics possessing increased whole blood values of one or more of the following heavy metals; chromium, copper, lead, manganese and nickel, were studied for peripheral nerve affection by means of electromyography (both sensoric and motoric nerve potentials were recorded). The heavy metal contents were rela... | ['Action Potentials', 'Adult', 'Aged', 'Chromium', 'Copper', 'Electromyography', 'Environmental Exposure', 'Erythrocytes', 'Female', 'Humans', 'Lead', 'Levulinic Acids', 'Male', 'Manganese', 'Metals', 'Middle Aged', 'Neural Conduction', 'Nickel', 'Occupational Diseases', 'Oils', 'Oxidoreductases', 'Peripheral Nervous S... | 183,452 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['M01.060.116.100'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E01.370.405.255', 'E01.370.530.255'], ['N06.850.460.350'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An adolescent with chronic giardiasis mimicking anorexia nervosa. | A 13-year-old Hispanic female presented with symptoms of abdominal pain, amenorrhea, and unintentional weight loss of 11 kg. Preliminary investigation yielded no immediate causes, and an initial differential included inflammatory bowel disease (IBD), celiac disease, as well as viral, bacterial, or parasitic gastrointes... | ['Adolescent', 'Anorexia Nervosa', 'Antiprotozoal Agents', 'Chronic Disease', 'Diagnosis, Differential', 'Female', 'Giardiasis', 'Humans', 'Metronidazole', 'Missouri'] | 23,893,673 | [['M01.060.057'], ['F03.400.125'], ['D27.505.954.122.250.100'], ['C23.550.291.500'], ['E01.171'], ['C01.610.432.481', 'C01.610.752.400', 'C06.405.469.452.481'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.640.672.500', 'D03.383.129.308.658.500'], ['Z01.107.567.875.510.515']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Passive sampling coupled to ultraviolet irradiation: a useful analytical approach for studying oxygenated polycyclic aromatic hydrocarbon formation in bioavailable mixtures. | The authors investigated coupling passive sampling technologies with ultraviolet irradiation experiments to study polycyclic aromatic hydrocarbon (PAH) and oxygenated PAH transformation processes in real-world bioavailable mixtures. Passive sampling device (PSD) extracts were obtained from coastal waters impacted by th... | ['Environmental Monitoring', 'Gulf of Mexico', 'Oregon', 'Oxygen', 'Petroleum Pollution', 'Photolysis', 'Polycyclic Aromatic Hydrocarbons', 'Ultraviolet Rays', 'Water Pollutants, Chemical'] | 24,123,227 | [['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.756.092.325'], ['Z01.107.567.875.560.550', 'Z01.107.567.875.580.550'], ['D01.268.185.550', 'D01.362.670'], ['N06.850.460.660'], ['G02.740.685'], ['D02.455.426.559.847', 'D04.615'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659',... | ['Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Kainate activated single channel currents as revealed by domoic acid. | We have studied the properties of kainic acid receptor-activated channels using domoic acid as an agonist. Similarities of the electrophysiological, pharmacological and noise properties of domoic acid and kainic acid-evoked currents confirm that domoate is a potent and specific agonist of the kainate receptor. Single-c... | ['Animals', 'Cells, Cultured', 'Cerebellum', 'Electrophysiology', 'Ion Channels', 'Kainic Acid', 'Magnesium', 'Membrane Potentials', 'Neuromuscular Depolarizing Agents', 'Rats', 'Rats, Inbred Strains', 'Receptors, Kainic Acid', 'Receptors, Neurotransmitter'] | 1,705,880 | [['B01.050'], ['A11.251'], ['A08.186.211.132.810.428.200'], ['H01.158.344.528', 'H01.158.782.236'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D03.383.773.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['D27.505.6... | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamic mechanical analysis of collagen fibrils at the nanoscale. | Low frequency (0.1-2 Hz) dynamic mechanical analysis on individual type I collagen fibrils has been carried out using atomic force microscopy (AFM). Both the elastic (static) and viscous (dynamic) responses are correlated to the characteristic axial banding, gap and overlap regions. The elastic modulus (?5 GPa) on the ... | ['Animals', 'Biomechanical Phenomena', 'Collagen Type I', 'Elasticity', 'Hardness Tests', 'Mechanical Phenomena', 'Nanostructures', 'Rats', 'Tendons', 'Viscosity'] | 22,100,091 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['G01.374.590'], ['E05.417', 'E05.570.500.500', 'G01.374.647.457', 'G01.374.687.500'], ['G01.374'], ['J01.637.512'], ['B01.050.150.900.649.313.992.635.505.700'], ['A02.880'], ['G02.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Neurophysiological findings among workers exposed to organic solvents. | Neurophysiological findings among patients with solvent poisoning and among groups with long-term occupational exposure to various solvents are reviewed. Hydrocarbons with six carbon atoms have been shown to cause peripheral neuropathy, which can be revealed with electroneurography and electromyography. Various mixture... | ['Central Nervous System', 'Electric Conductivity', 'Electroencephalography', 'Environmental Exposure', 'Evoked Potentials, Visual', 'Humans', 'Nervous System', 'Nervous System Physiological Phenomena', 'Peripheral Nerves', 'Solvents', 'Time Factors'] | 6,962,646 | [['A08.186'], ['G01.358.500.249.277'], ['E01.370.376.300', 'E01.370.405.245'], ['N06.850.460.350'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08'], ['G11.561'], ['A08.800.800'], ['D27.720.844'], ['G01.910.857']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Diagnosis of the presence of meconium in amniotic fluid by dispersion curves of the longitudinal relaxations of protons]. | Dispersion curves of the longitudinal relaxation T1 of protons in healthy amniotic fluid in a meconium solution are distinct at low Larmor frequencies (V0 less than 100 kHz). We are thus able to distinguish these fluids by T1 measurements in this range. | ['Amniotic Fluid', 'Female', 'Fetal Diseases', 'Humans', 'Magnetic Resonance Spectroscopy', 'Meconium', 'Pregnancy', 'Prenatal Diagnosis'] | 120,784 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distinct effects of tetragastrin in rat gastroduodenal mucosa on mucin content and mucosal protective action against histamine-induced injury. | We examined the effects of tetragastrin on mucin (mucus glycoprotein) content and mucosal damage in the rat stomach and duodenum. Following an injection of tetragastrin (12, 120, or 400 microg/kg subcutaneously), no macroscopic damage was found to the gastric mucosa but an increase in corpus mucin content was noted, wh... | ['Animals', 'Dose-Response Relationship, Drug', 'Duodenum', 'Gastric Mucosa', 'Histamine', 'Intestinal Mucosa', 'Male', 'Mucins', 'Rats', 'Rats, Wistar', 'Tetragastrin'] | 9,590,421 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['A03.556.124.684.124', 'A03.556.875.249'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['A03.556.124.369', 'A10.615.550.444'], ['D12.776.395.560.631'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Cytokinin Oxidase/Dehydrogenase CKX1 Is a Membrane-Bound Protein Requiring Homooligomerization in the Endoplasmic Reticulum for Its Cellular Activity. | Degradation of the plant hormone cytokinin is controlled by cytokinin oxidase/dehydrogenase (CKX) enzymes. The molecular and cellular behavior of these proteins is still largely unknown. In this study, we show that CKX1 is a type II single-pass membrane protein that localizes predominantly to the endoplasmic reticulum ... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Endoplasmic Reticulum', 'Green Fluorescent Proteins', 'Membrane Proteins', 'Oxidoreductases', 'Protein Domains', 'Protein Multimerization', 'Protein Sorting Signals', 'Protein Stability', 'Recombinant Fusion Proteins'] | 29,301,955 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['A11.284.430.214.190.875.248'], ['D12.776.532.265'], ['D12.776.543'], ['D08.811.682'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['G02.111.694'], ['D12.644.770', 'G02.111.570.060.670'], ['G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
High-level expression of three members of the murine angiogenin family in Escherichia coli and purification of the recombinant proteins. | Angiogenin (Ang) is a small basic protein which belongs to the pancreatic ribonuclease superfamily. It potently induces the formation of new blood vessels and has emerged as a promising anticancer target. Mice possess genes encoding one ortholog (mAng) and three homologs of Ang, designated angiogenin-related protein (m... | ['Angiogenesis Inducing Agents', 'Animals', 'Escherichia coli', 'Mice', 'Multigene Family', 'Protein Biosynthesis', 'Proteins', 'Recombinant Proteins', 'Ribonuclease, Pancreatic', 'Ribonucleases'] | 11,437,607 | [['D27.505.696.377.077.077'], ['B01.050'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.360.340.024.340.645'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D12.776'], ['D12.776.828'], ['D08.811.277.352.355.350.715', 'D08.811.277.352.700.350.715'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ASHP guidelines on surgery and anesthesiology pharmaceutical services. American Society of Health-System Pharmacists. | Pharmaceutical services in surgery and anesthesiology should be the standard of practice in health care organizations across the United States. Although not essential, an onsite satellite pharmacy would help in the provision of these services. A majority of distribution-related activities should be done by technicians.... | ['Anesthesiology', 'Drug Compounding', 'Economics, Hospital', 'General Surgery', 'Humans', 'Pharmaceutical Services', 'Public Policy'] | 10,344,614 | [['H02.403.066'], ['E05.916.270'], ['N03.219.262'], ['H02.403.810.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.668'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Bio-inspired motifs via tandem assembly of polypeptides for mineralization of stable CaCO3 structures. | A macromolecular-assembly of polypeptides constructs a network of anionic and cationic charges vital for recognizing and coassembling Ca(2+) and CO(3)(2-) ions to mineralize and stabilize different mineral forms of CaCO(3) with core-shell or solid morphologies in an aqueous solution. | ['Calcium Carbonate', 'Crystallization', 'Microscopy, Electron, Scanning', 'Peptides'] | 22,792,540 | [['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['E05.196.300', 'G02.171'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D12.644']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Matrix-driven translocation: dependence on interaction of amino-terminal domain of fibronectin with heparin-like surface components of cells or particles. | During the process of matrix-driven translocation, certain types of cells or polystyrene latex beads are transported between compositionally different regions of a collagen matrix. Under appropriate conditions this translocation depends on an interaction between the cell or particle surface and fibronectin. We now show... | ['Amino Acid Sequence', 'Antibodies, Monoclonal', 'Binding Sites', 'Biophysical Phenomena', 'Biophysics', 'Collagen', 'Dextran Sulfate', 'Dextrans', 'Epitopes', 'Fibronectins', 'Gels', 'Heparin', 'Heparitin Sulfate', 'Humans', 'Latex', 'Microspheres', 'Motion', 'Peptide Fragments', 'Protein Binding', 'Surface Propertie... | 2,440,029 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.120'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D09.698.365.272.300'], ['D05.750.078.562.272', 'D09.698.365.272'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Effects of maternal genetic polymorphisms in vitamin D-binding protein and serum 25-hydroxyvitamin D concentration on infant birth weight. | OBJECTIVE: Vitamin D deficiency is a common problem during pregnancy and might contribute to adverse birth outcomes. Vitamin D-binding protein plays a key role in regulating vitamin D metabolism. We investigated whether maternal genetic variation in GC, the gene encoding vitamin-D binding protein, modulates the relatio... | ['Adult', 'Alleles', 'Birth Weight', 'Body Mass Index', 'Chromatography, Liquid', 'Female', 'Fetal Blood', 'Gene Expression Regulation', 'Genotype', 'Genotyping Techniques', 'Humans', 'Infant', 'Male', 'Maternal Nutritional Physiological Phenomena', 'Multivariate Analysis', 'Polymorphism, Single Nucleotide', 'Pregnancy... | 28,241,988 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.196.181.400'], ['A12.207.152.200', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Purification and characterization of fish surface mucin. | Fish surface mucin from Pampus argenteus was extracted with different organic solvents and the residue passed through Sephadex G-200. The major peak was purified by DEAE-Cellulose chromatography and five fractions were obtained. Carbohydrate and protein contents showed that major peak is a glycoprotein. Rechromatograph... | ['Amino Acids', 'Animals', 'Carbohydrate Conformation', 'Carbohydrates', 'Chemical Fractionation', 'Chromatography, DEAE-Cellulose', 'Chromatography, Gel', 'Fishes', 'Fucose', 'Hydrolysis', 'Mucins', 'N-Acetylneuraminic Acid', 'Sialic Acids', 'Sulfates'] | 3,610,597 | [['D12.125'], ['B01.050'], ['G02.111.570.820.235'], ['D09'], ['E05.196.155'], ['E05.196.181.400.383.349'], ['E05.196.181.400.250'], ['B01.050.150.900.493'], ['D09.254.488'], ['G02.380'], ['D12.776.395.560.631'], ['D02.241.081.844.562.668.050', 'D02.241.511.902.562.668.050', 'D09.067.687.668.030', 'D09.811.589.668.030']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pigment sludge and stone formation in the acutely ligated dog gallbladder. | We studied the effects of stasis of gallbladder bile in a dog model. Three days after cystic duct ligation, all gallbladders contained sludge, and the mucosa was covered by densely adherent mucus with solid particles 1-4 mm in diameter (gravel). Thirty percent of the animals developed stones (greater than 4 mm), which ... | ['Animals', 'Bile Acids and Salts', 'Bile Pigments', 'Bilirubin', 'Cholelithiasis', 'Cholestasis', 'Cholesterol', 'Cystic Duct', 'Dogs', 'Female', 'Gallbladder', 'Ligation', 'Male', 'Mucins', 'Time Factors'] | 6,618,107 | [['B01.050'], ['D04.210.500.105'], ['D03.383.129.578.840.249', 'D03.633.400.909.249', 'D04.345.783.249', 'D23.767.193'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['C06.130.409'], ['C06.130.120.135'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide--V. Factors governing the response of murine tumors to tiazofurin. | The pharmacological effects and metabolism of tiazofurin have been compared in the six transplantable tumors comprising the NCI rodent tumor panel, viz. the P388 leukemia (S); the L1210 leukemia (S); the Lewis lung carcinoma (S); the B16 melanoma (R); the colon 38 carcinoma (R); and the M5076 sarcoma (R), where (S) den... | ['Adenine Nucleotides', 'Animals', 'Antineoplastic Agents', 'Biotransformation', 'Dose-Response Relationship, Drug', 'Drug Resistance', 'Female', 'IMP Dehydrogenase', 'Male', 'Mice', 'Neoplasms, Experimental', 'Nucleotides', 'Ribavirin', 'Ribonucleosides'] | 6,143,562 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['B01.050'], ['D27.505.954.248'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984'], ['D08.811.682.047.820.450'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.619', 'E05.598.500.496'], ['D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Methadone conversion in infants and children: Retrospective cohort study of 199 pediatric inpatients. | OBJECTIVE: Methadone administration has increased in pediatric clinical settings. This review is an attempt to ascertain an equianalgesic dose ratio for methadone in the pediatric population using standard adult dose conversion guidelines.SETTING: US tertiary children's hospital.PATIENTS: Hospitalized pediatric patient... | ['Administration, Oral', 'Adolescent', 'Age Factors', 'Analgesics, Opioid', 'Child', 'Child, Preschool', 'Consciousness', 'Drug Administration Schedule', 'Drug Dosage Calculations', 'Drug Monitoring', 'Drug Overdose', 'Drug Substitution', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Infant, Newborn', 'Inpatients', 'Int... | 27,194,197 | [['E02.319.267.100'], ['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['M01.060.406'], ['M01.060.406.448'], ['F02.463.188.409', 'F02.830.233'], ['E02.319.283'], ['E02.319.305'], ['E01.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endoplasmic reticulum stress and glycogen synthase kinase-3â activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis. | OBJECTIVE: The goal of this study was to examine the role of endoplasmic reticulum (ER) stress signaling and the contribution of glycogen synthase kinase (GSK)-3â activation in hyperglycemic, hyperhomocysteinemic, and high-fat-fed apolipoprotein E-deficient (apoE(-/-)) mouse models of accelerated atherosclerosis.METHOD... | ['Animals', 'Aorta', 'Apolipoproteins E', 'Atherosclerosis', 'Diet, High-Fat', 'Disease Models, Animal', 'Endoplasmic Reticulum Stress', 'Enzyme Activation', 'Enzyme Inhibitors', 'Fatty Liver', 'Female', 'Glycogen Synthase Kinase 3', 'Glycogen Synthase Kinase 3 beta', 'Hep G2 Cells', 'Humans', 'Hyperglycemia', 'Hyperho... | 21,998,135 | [['B01.050'], ['A07.015.114.056'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126.307'], ['G07.203.650.240.267'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G04.434'], ['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['C06.552.241'], ['D05.500.117.875', 'D08.811.913.696.620.6... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of formaldehyde on the isolated phrenic nerve and the phrenic nerve-diaphragm preparation of the rat, in vitro. | Formaldehyde, 0.5-4.5 mM, increased the threshold for electrical excitation of the nerve, and led to a partial and reversible inhibition of the compound action potential (cAP). The depression was not enhanced by high frequency stimulation. At 8.9 mM or higher, the depression of the nerve excitability could not be rever... | ['Action Potentials', 'Animals', 'Diaphragm', 'Electric Stimulation', 'Electromyography', 'Female', 'Formaldehyde', 'In Vitro Techniques', 'Male', 'Microelectrodes', 'Neuromuscular Junction', 'Phrenic Nerve', 'Rats', 'Rats, Inbred Strains', 'Synaptic Transmission'] | 2,995,883 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A02.633.567.900.300'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['D02.047.407'], ['E05.481'], ['E07.305.250.500'], ['A08.800.550.550.550', 'A08.850.550.550', 'A11.284.149.165.420.780.550.550'], ['A08.800.800.720.150.700'], ['B01.050.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mortality among residents of Uravan, Colorado who lived near a uranium mill, 1936-84. | A cohort mortality study was conducted of all adult residents who ever lived in Uravan, Colorado, a company town built around a uranium mill. Vital status was determined through 2004 and standardised mortality analyses conducted for 1905 men and women alive after 1978 who lived for at least 6 months between 1936 and 19... | ['Adult', 'Causality', 'Cohort Studies', 'Colorado', 'Demography', 'Environmental Exposure', 'Female', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Male', 'Mining', 'Occupational Exposure', 'Radon', 'Retrospective Studies', 'Sex Distribution', 'Uranium'] | 17,768,330 | [['M01.060.116'], ['N05.715.350.200', 'N06.850.490.625'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.107.567.875.760.210'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['N06.850.460.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'],... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential. | Apolipoprotein A-II (apoA-II), the second major high-density lipoprotein (HDL) apolipoprotein, has been linked to familial combined hyperlipidemia. Human apoA-II transgenic mice constitute an animal model for this proatherogenic disease. We studied the ability of human apoA-II transgenic mice HDL to protect against oxi... | ['1-Alkyl-2-acetylglycerophosphocholine Esterase', 'Animals', 'Aorta', 'Aortic Diseases', 'Apolipoprotein A-I', 'Apolipoprotein A-II', 'Arteriosclerosis', 'Aryldialkylphosphatase', 'Cholesterol, HDL', 'Diet, Atherogenic', 'Dinoprost', 'Disease Models, Animal', 'Female', 'Gene Expression Regulation', 'Humans', 'Hyperlip... | 15,388,641 | [['D08.811.277.352.100.680.750.937.249'], ['B01.050'], ['A07.015.114.056'], ['C14.907.109'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D10.532.091.200.150', 'D12.776.070.400.200.150', 'D12.776.521.120.200.150'], ['C14.907.137.126'], ['D08.811.277.352.660.500'], ['D04.210.500.247.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. | Metabolomics can be used to identify potential markers and discover new targets for future therapeutic interventions. Here, we developed a novel application of the metabonomics method based on gas chromatography-mass spectrometry (GC/MS) analysis and principal component analysis (PCA) for rapidly exploring the anticanc... | ['Antineoplastic Agents', 'Apoptosis', 'Carcinoma, Hepatocellular', 'Cell Proliferation', 'Glycolysis', 'Hep G2 Cells', 'Humans', 'Liver Neoplasms', 'Metabolomics', 'Mitochondria', 'Models, Biological', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction', 'Tumor Suppressor Protein p53', 'Withanolides'] | 27,416,811 | [['D27.505.954.248'], ['G04.146.954.035'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Routes to improving the reliability of low level DNA analysis using real-time PCR. | BACKGROUND: Accurate quantification of DNA using quantitative real-time PCR at low levels is increasingly important for clinical, environmental and forensic applications. At low concentration levels (here referring to under 100 target copies) DNA quantification is sensitive to losses during preparation, and suffers fro... | ['Artifacts', 'Base Sequence', 'Computer Simulation', 'Computer Systems', 'Microchemistry', 'Models, Genetic', 'Molecular Sequence Data', 'Oligonucleotide Array Sequence Analysis', 'Quality Control', 'Reproducibility of Results', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Sequenc... | 16,824,215 | [['E05.047'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['L01.224.160'], ['L01.224.230'], ['E05.196.620', 'H01.181.650'], ['E05.599.395.397'], ['L01.453.245.667'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['J01.897.608'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Topographic anatomy of the lingual nerve and variations in communication pattern of the mandibular nerve branches. | We made a thorough observation of the morphology and course of the lingual nerve (LN) and inferior alveolar nerve (IAN) to clarify their topographical relationships in the infratemporal fossa and in the paralingual area. Thirty-two Korean hemi-sectioned heads were dissected macroscopically and microscopically from a cl... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cadaver', 'Female', 'Humans', 'Lingual Nerve', 'Male', 'Mandibular Nerve', 'Middle Aged'] | 14,586,562 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.120.760.500.450'], ['A08.800.800.120.760.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genomic aberrations in the HTPAP promoter affect tumor metastasis and clinical prognosis of hepatocellular carcinoma. | We previously reported that the intronic tagSNP +357G/C in the metastasis suppressor HTPAP is associated with metastasis and prognosis of hepatocellular carcinoma (HCC). The aim of this study was to investigate whether SNPs in the HTPAP promoter modulate HTPAP expression and prognosis of HCC. Genomic DNA from 572 micro... | ['Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Female', 'Gene Expression Regulation, Neoplastic', 'Genomics', 'Haplotypes', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Phosphatidate Phosphatase', 'Polymorphism, Single Nucleotide', 'Prognosis', 'Promoter Regio... | 24,603,412 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.308.370'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.0... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Is elderspeak appropriate? A survey of certified nursing assistants. | Elderspeak is a form of patronizing speech that is sometimes used with older adults and can result in unintended negative consequences. Certified nursing assistants (CNAs) working in long-term care facilities may be particularly prone to using elderspeak because they frequently interact with vulnerable and frail older ... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Attitude of Health Personnel', 'Communication', 'Female', 'Geriatric Nursing', 'Homes for the Aged', 'Humans', 'Language', 'Long-Term Care', 'Male', 'Midwestern United States', 'Nurse-Patient Relations', 'Nursing Assistants', 'Nursing ... | 24,716,644 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.050', 'N05.300.100'], ['F01.145.209', 'L01.143'], ['H02.478.676.236', 'N02.421.533.245'], ['J03.775.462', 'N02.278.825.462... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Org... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Application of transglutaminase and fermizyme for sensory quality improvement of pastry. | The objective of the model experiment was to find out the improving effect of two selected enzymes, transglutaminase (i) and fermizyme (ii), added at different concentrations of 4.5 mg and 7.5 mg/300 g flour (i) and 15 mg and 60 mg/300 g flour (ii) to the pastry dough on the quality of end products. The investigation w... | ['Amylases', 'Chemical Phenomena', 'Chemistry, Physical', 'Color', 'Cooking', 'Endopeptidases', 'Flour', 'Food Handling', 'Food Preservation', 'Food Technology', 'Food-Processing Industry', 'Glycoside Hydrolases', 'Humans', 'Odorants', 'Taste', 'Time Factors', 'Transglutaminases'] | 12,866,618 | [['D08.811.277.450.066'], ['G02'], ['H01.181.529'], ['G01.590.540.199'], ['J01.576.423.200.200'], ['D08.811.277.656.300'], ['G07.203.300.484', 'J02.500.484'], ['J01.576.423.200'], ['J01.576.423.850.700'], ['J01.576.423.850'], ['J01.576.423.200.400'], ['D08.811.277.450'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Antitumor effect of TAT-oxygen-dependent degradation-caspase-3 fusion protein specifically stabilized and activated in hypoxic tumor cells. | Human solid tumors contain hypoxic regions that have considerably lower oxygen tension than normal tissues. These impart resistance to radiotherapy and anticancer chemotherapy, as well as predisposing to increased tumor metastases. To develop a potentially therapeutic protein drug highly specific for solid tumors, we c... | ['3T3 Cells', 'Adenocarcinoma', 'Amino Acid Sequence', 'Animals', 'Caspase 3', 'Caspases', 'Cell Hypoxia', 'Gene Products, tat', 'Humans', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Lung Neoplasms', 'Mice', 'Mice, Nude', 'Molecular Sequence Data', 'Oxygen', 'Pancreatic Neoplasms', 'Peptide Fragments', 'Protein Struc... | 11,929,818 | [['A11.251.210.100', 'A11.329.228.100'], ['C04.557.470.200.025'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.20... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Continued expansion of aortic necks after endovascular repair of abdominal aortic aneurysms. EVT Investigators. EndoVascular Technologies, Inc. | BACKGROUND: Longitudinal studies have revealed that the aortic segment proximal to an infrarenal abdominal aortic aneurysm (AAA) is at risk for continued enlargement after a standard aneurysm repair. Similarly, preliminary reports have shown expansion of one or both aortic necks after endovascular repair. Although some... | ['Aged', 'Aorta, Abdominal', 'Aortic Aneurysm, Abdominal', 'Blood Vessel Prosthesis Implantation', 'Dilatation, Pathologic', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Reoperation', 'Tomography, X-Ray Computed'] | 9,737,451 | [['M01.060.116.100'], ['A07.015.114.056.205'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E04.100.814.868.500', 'E04.650.200'], ['C23.300.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E04.690'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Born captive: A survey of the lion breeding, keeping and hunting industries in South Africa. | Commercial captive breeding and trade in body parts of threatened wild carnivores is an issue of significant concern to conservation scientists and policy-makers. Following a 2016 decision by Parties to the Convention on International Trade in Endangered Species of Wild Fauna and Flora, South Africa must establish an a... | ['Animals', 'Animals, Wild', 'Breeding', 'Commerce', 'Conservation of Natural Resources', 'Endangered Species', 'Female', 'Industry', 'Internationality', 'Lions', 'Male', 'Population Density', 'Pregnancy', 'South Africa', 'Sports', 'Surveys and Questionnaires'] | 31,136,596 | [['B01.050'], ['B01.050.050.300'], ['E05.820.150', 'G05.090'], ['J01.219'], ['J01.256', 'N06.230.080'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['J01.576'], ['I01.615'], ['B01.050.150.900.649.313.750.377.750.600.500'], ['N01.224.600', 'N06.850.505.400.600'], ['G08.686.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Expression of á-crystallin in the retina of human sympathetic ophthalmia. | Sympathetic ophthalmia (SO) is a bilateral, granulomatous, intraocular inflammation that occurs following a penetrating injury to one eye, and has the potential to cause blindness of both eyes. The aim of this study was to examine the expression of á-crystallin and to detect apoptotic cells in the retina of human eyes ... | ['Apoptosis', 'Gene Expression Regulation', 'Humans', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'Ophthalmia, Sympathetic', 'Photoreceptor Cells', 'Retina', 'alpha-Crystallin A Chain', 'alpha-Crystallin B Chain', 'alpha-Crystallins'] | 22,052,021 | [['G04.146.954.035'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Procedural risks versus theology: chorionic villus sampling for Orthodox Jews at less than 8 weeks' gestation. | OBJECTIVE: According to Orthodox Jewish law, abortion is only permitted before 40 days post conception. This evaluation was performed to determine the feasibility and safety of performing chorionic villus sampling (CVS) at 7 to 8 weeks' gestation so that genetic results would be useful for these patients.STUDY DESIGN: ... | ['Abortion, Spontaneous', 'Chorionic Villi Sampling', 'Female', 'Humans', 'Judaism', 'Limb Deformities, Congenital', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimester, First', 'Risk Assessment'] | 12,066,086 | [['C13.703.039', 'G08.686.784.769.496.125'], ['E01.370.225.500.384.100.149', 'E01.370.225.998.054.149', 'E01.370.378.630.150', 'E01.370.388.100.150', 'E04.074.149', 'E05.200.500.384.100.149', 'E05.200.998.054.149', 'E05.242.384.100.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.844.385'], ['C05.660.585',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
IgG4-Aortopathy: An Underappreciated Cause of Non-Infectious Thoracic Aortitis. | IgG4 related thoracic aortitis is a recent addition to the differential diagnosis for inflammatory aortic disease - a condition which is often underappreciated until complications arise such as aneurysmal formation or aortic dissection. Currently, IgG4 aortitis remains a post-surgical diagnosis reliant on positive immu... | ['Adrenal Cortex Hormones', 'Aortic Aneurysm, Thoracic', 'Aortic Rupture', 'Aortitis', 'Autoimmune Diseases', 'Female', 'Humans', 'Immunoglobulin G', 'Middle Aged'] | 28,511,923 | [['D06.472.040'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['C14.907.109.320', 'C14.907.940.080'], ['C20.111'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.3... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Are Doctors familiar with enteral nutrition at home? Opinion poll in the province of Tarragona]. | At our hospital, there is an At-Home Enteral Nutrition programme (NED in its Spanish acronym) with participation of the Clinical Nutrition Unit and the Pharmacy Service. The products and all necessary material are dispensed directly to the patient's home and nutritional follow-up is carried out. As a lack of informatio... | ['Enteral Nutrition', 'Health Knowledge, Attitudes, Practice', 'Home Care Services', 'Humans', 'Spain', 'Surveys and Questionnaires'] | 14,682,180 | [['E02.421.360', 'E02.642.500.360'], ['F01.100.150.500', 'N05.300.150.410'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.846'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Lung function abnormalities after acute bronchiolitis. | Measurements of thoracic gas volume, airways resistance, and total respiratory resistance were measured in a group of babies with acute severe bronchiolitis. Assessments were made at convalescence, three to four months later, and after 12 months. Clinical histories were also taken 12 months after the acute episode. Res... | ['Acute Disease', 'Airway Resistance', 'Bronchiolitis, Viral', 'Humans', 'Infant', 'Lung Diseases, Obstructive', 'Lung Volume Measurements'] | 7,229,787 | [['C23.550.291.125'], ['E01.370.386.700.050', 'G09.772.060'], ['C01.748.099.135.321', 'C01.925.109', 'C08.127.446.135.321', 'C08.381.495.146.135.321', 'C08.730.099.135.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08.381.495'], ['E01.370.386.700.485']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
TRPV1 and TRPA1 channels in inflammatory pain: elucidating mechanisms. | Transient receptor potential (TRP) receptors are ion channels that mediate pain and inflammation. We provide evidence for the distinct roles of TRPV1 and TRPA1 in arthritis. | ['Animals', 'Arthritis, Experimental', 'Disease Models, Animal', "Freund's Adjuvant", 'Humans', 'Inflammation', 'Mice', 'Mice, Knockout', 'Pain', 'TRPA1 Cation Channel', 'TRPV Cation Channels', 'Transient Receptor Potential Channels'] | 22,211,974 | [['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D20.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of team experience on outcomes of endovascular stenting of abdominal aortic aneurysms. | OBJECTIVE: To determine whether the experience of the specialist team was associated with adverse events following endovascular treatment of abdominal aortic aneurysms.METHODS: The EUROSTAR database is a voluntary registry of 2863 patients admitted to 93 hospitals in Europe with an abdominal aortic aneurysm treated wit... | ['Adult', 'Aged', 'Aortic Aneurysm, Abdominal', 'Aortic Rupture', 'Blood Vessel Prosthesis Implantation', 'Clinical Competence', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Patient Care Team', 'Postoperative Complications', 'Retrospective Studies', 'Stents', 'Surv... | 12,389,234 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['E04.100.814.868.500', 'E04.650.200'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Phase II study of a combination of S-1 and paclitaxel in patients with unresectable or metastatic gastric cancer. | OBJECTIVES: A phase II study of weekly paclitaxel combined with S-1, a novel oral fluoropyrimidine, was performed to evaluate the efficacy and tolerability in unresectable or metastatic gastric cancer.PATIENTS AND METHODS: Twenty-nine patients with unresectable and/or metastatic gastric cancer were enrolled in the stud... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Drug Combinations', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oxonic Acid', 'Paclitaxel', 'Stomach Neoplasms', 'Tegafur', 'Treatment Outcome'] | 18,544,958 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.383.931.640'], ['D02.455.426.392.368.242.888.777', 'D02.455.849.291.850.777'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.24... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
"Referred visual sensations": rapid perceptual elongation after visual cortical deprivation. | Visual perceptual distortion (i.e., elongation) has been demonstrated in a single case study after several months of cortical deprivation after a stroke. Here we asked whether similar perceptual elongation can be observed in healthy participants after deprivation and, crucially, how soon after deprivation this elongati... | ['Adult', 'Dominance, Ocular', 'Female', 'Humans', 'Judgment', 'Male', 'Middle Aged', 'Optic Disk', 'Pattern Recognition, Visual', 'Reaction Time', 'Sensory Deprivation', 'Time Factors', 'Visual Cortex', 'Visual Fields', 'Young Adult'] | 19,605,633 | [['M01.060.116'], ['G11.561.225.425.500', 'G14.264'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['M01.060.116.630'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.696... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.