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Up regulation of miR-96-5p is responsible for TiO2
Titanium dioxide nanoparticles (TiO2 NPs) are used extensively in our daily lives, and their toxic effects on the placenta have been reported. Animal studies indicated that placental development is impaired after maternal exposure of TiO2 NPs, but the underlying mechanisms remain largely unknown. In the present study, ...
['Cell Line', 'Cell Movement', 'Cytoskeletal Proteins', 'Cytoskeleton', 'Humans', 'Metal Nanoparticles', 'MicroRNAs', 'Microtubules', 'RNA, Messenger', 'Titanium', 'Trophoblasts', 'Up-Regulation']
31,226,636
[['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['D12.776.220'], ['A11.284.430.214.190.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512.600.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['A11.284.430.214.190.750.602'], ['D13.444.735.544'], ['D01.268.557.800', 'D01....
['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]']
1
1
0
1
0
0
1
0
0
1
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Prostaglandin regulation of H+ secretion in amphibian epithelia.
The role of prostaglandins in regulating H+ excretion in amphibian epithelia was investigated. The abdominal skin of the southern leopard frog Rana pipiens and the urinary bladder of the toad Bufo marinus were used to measure proton excretion across their mucosal surface. Prostaglandin F2 alpha (PGF2 alpha) produced a ...
['Amphibians', 'Animals', 'Bufo marinus', 'Epithelium', 'Hydrogen', 'Ions', 'Mitochondria', 'Prostaglandins', 'Rana pipiens', 'Second Messenger Systems', 'Skin', 'Urinary Bladder']
1,903,604
[['B01.050.150.900.090'], ['B01.050'], ['B01.050.150.900.090.180.210.580'], ['A10.272'], ['D01.268.406', 'D01.362.340'], ['D01.248.497'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['B01.050.150.900.090.180.708.310'], ['G02.111.820.800', 'G04.835.800'], ['A17.815...
['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
1
1
0
1
0
0
1
0
0
0
0
0
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0
Association between distress and knowledge among parents of autistic children.
Understanding the overall utility of biological testing for autism spectrum disorder (ASD) is essential for the development and integration of biomarkers into routine care. One measure related to the overall utility of biological testing is the knowledge that a person has about the condition he/she suffers from. Howeve...
['Adult', 'Autism Spectrum Disorder', 'Biomarkers', 'Chromosomes, Human', 'Female', 'Genetic Counseling', 'Genetic Testing', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Longitudinal Studies', 'Male', 'Microarray Analysis', 'Middle Aged', 'Parents', 'Socioeconomic Factors', 'Stress, Psychological', 'Surveys and ...
31,557,237
[['M01.060.116'], ['F03.625.164.113'], ['D23.101'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.1...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Ph...
1
1
0
1
1
1
1
1
1
0
0
1
1
0
[Features of development, clinical picture and surgical treatment policy of destructive forms of pulmonary tuberculosis in the North].
In 135 patients, follow-up clinical, X-ray, immunological, and pathomorphological studies revealed that destructive changes in the form took place as an extensive specific process involving more than one lobe with bronchogenic dissemination and, commonly, as caseous pneumonia. Despite the extensive destructive changes,...
['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Siberia', 'Treatment Outcome', 'Tuberculosis, Pulmonary']
9,235,580
[['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['Z01.252.122.500.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C01.1...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]']
0
1
1
0
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High levels of thyrotropin-releasing hormone precursor peptide immunoreactivity and binding substance occur in human cerebrospinal fluid.
A thyrotropin-releasing hormone (TRH) precursor peptide, pGlu-His-Pro-Gly (TRH-Gly) and related peptides were measured in human cerebrospinal fluid (CSF) with a TRH-Gly radiommunoassay and the levels of immunoreactivity (IR) were found to be 136- to 352-fold higher than the corresponding levels of TRH-IR. TRH-IR levels...
['Alzheimer Disease', 'Amino Acid Sequence', 'Chromatography, High Pressure Liquid', 'Humans', 'Molecular Sequence Data', 'Multiple Sclerosis', 'Protein Precursors', 'Pyrrolidonecarboxylic Acid', 'Thyrotropin-Releasing Hormone']
1,904,138
[['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['D12.776.811'], ['D03.383.773.812.718', 'D12.125.067....
['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]']
0
1
1
1
1
1
1
0
0
0
1
0
0
0
A hybrid evolutionary data driven model for river water quality early warning.
China's fast pace industrialization and growing population has led to several accidental surface water pollution events in the last decades. The government of China, after the 2005 Songhua River incident, has pushed for the development of early warning systems (EWS) for drinking water source protection. However, there ...
['Ammonia', 'Biological Oxygen Demand Analysis', 'Carbon', 'China', 'Cities', 'Drinking Water', 'Environmental Monitoring', 'Models, Theoretical', 'Neural Networks, Computer', 'Nitrogen', 'Rivers', 'Time Factors', 'Water Pollution', 'Water Quality']
24,833,523
[['D01.362.075', 'D01.625.050'], ['N06.850.460.350.080.500', 'N06.850.780.375.349'], ['D01.268.150'], ['Z01.252.474.164'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['N06.850.460.350.080', 'N06.850.780....
['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]']
0
0
0
1
1
0
1
0
0
1
1
0
1
1
The diagnostic accuracy of CT-guided percutaneous core needle biopsy and fine needle aspiration in pulmonary lesions: a meta-analysis.
AIM: To determine and compare the diagnostic value of computed tomography (CT)-guided percutaneous core needle biopsy (PCNB) and percutaneous fine-needle aspiration biopsy (PNAB) in pulmonary lesions.MATERIALS AND METHODS: PubMed, EMBASE, and the Web of Science were systematically searched for relevant studies that inv...
['Biopsy, Fine-Needle', 'Biopsy, Large-Core Needle', 'Diagnosis, Differential', 'Humans', 'Image-Guided Biopsy', 'Lung Diseases', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed']
26,545,460
[['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.225.500.384.100.119.750', 'E01.370.225.998.054.119.750', 'E01.370.388.100.100.750', 'E04.07...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]']
0
1
1
0
1
0
1
0
0
0
0
0
1
0
Sphingosine-1-phosphate analogue FTY720 causes lymphocyte redistribution and hypercholesterolemia in ApoE-deficient mice.
OBJECTIVE: Resident immune cells are a hallmark of atherosclerotic lesions. The sphingolipid analogue drug FTY720 mediates retrafficking of immune cells and inhibits their homing to inflammatory sites. We have evaluated the effect of FTY720 on atherogenesis and lipid metabolism.METHODS AND RESULTS: ApoE-/- mice on a no...
['Animals', 'Apolipoproteins E', 'Atherosclerosis', 'Fingolimod Hydrochloride', 'Hypercholesterolemia', 'Immunosuppressive Agents', 'Lipid Metabolism', 'Lymphocyte Subsets', 'Lymphocytes', 'Lymphopenia', 'Lysophospholipids', 'Male', 'Mice', 'Mice, Knockout', 'Propylene Glycols', 'Sphingosine', 'Spleen']
17,761,943
[['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126.307'], ['D02.033.100.700.350', 'D02.033.455.706.431', 'D02.092.063.700.350'], ['C18.452.584.500.500.396'], ['D27.505.696.477.656'], ['G03.458'], ['A11.118.637.555.567.550', 'A15.145.229.637.555.567.550', 'A15.382.490.555....
['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
1
1
1
0
0
1
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Expression of CD24 in cholangiocarcinoma cells is associated with disease progression and reduced patient survival.
Cholangiocarcinoma is frequently found to invade local tissues and metastasize to distal organs. We investigated the expression of CD24 in cholangiocarcinoma samples and its prognostic significance. In addition, the cellular function of CD24 was studied in the RMCCA1 cholangiocarcinoma cell line. High CD24 expression s...
['Bile Duct Neoplasms', 'Bile Ducts, Intrahepatic', 'CD24 Antigen', 'Cell Adhesion', 'Cell Growth Processes', 'Cell Line, Tumor', 'Cell Movement', 'Cholangiocarcinoma', 'Disease Progression', 'Drug Resistance, Neoplasm', 'Humans', 'Lymphatic Metastasis', 'Matrix Metalloproteinase 7', 'Matrix Metalloproteinase 9', 'Mult...
21,687,942
[['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['A03.159.183.158', 'A03.620.150'], ['D12.776.395.550.200.098', 'D12.776.395.550.448.120', 'D12.776.543.484.500.120', 'D12.776.543.550.200.124', 'D12.776.543.550.418.120', 'D23.050.285.018', 'D23.050.301.350.098'], ['G04.022'], ['G04.161...
['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
HIV drug resistance mutations among patients failing second-line antiretroviral therapy in Rwanda.
BACKGROUND: Studies of patients failing second-line antiretroviral therapy (ART) in resource-limited settings (RLS) are few. Evidence suggests most patients who appear to be virologically failing do so not due to drug resistance but to poor adherence, which, if properly addressed, could allow continued use of less expe...
['Adult', 'Anti-HIV Agents', 'Drug Resistance, Viral', 'Female', 'HIV Infections', 'HIV-1', 'Humans', 'Male', 'Medication Adherence', 'Middle Aged', 'Mutation', 'Rwanda']
26,562,173
[['M01.060.116'], ['D27.505.954.122.388.077.088'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F0...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]']
0
1
1
1
0
1
1
0
0
0
0
1
1
1
Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals.
In addition to histamine, leukotriene C4 (LTC4) might also play a role in mediating cold urticaria wheals. To study the significance of LTC4 vs. histamine, 6 patients with cold urticaria were challenged with the ice cube test before and after ingestion of 10 mg cetirizine (antihistamine), 10 mg montelukast (leukotriene...
['Acetates', 'Adult', 'Anti-Allergic Agents', 'Cetirizine', 'Cold Temperature', 'Female', 'Histamine', 'Humans', 'Leukotriene Antagonists', 'Leukotriene C4', 'Male', 'Middle Aged', 'Quinolines', 'Urticaria']
17,225,008
[['D02.241.081.018', 'D10.251.400.045'], ['M01.060.116'], ['D27.505.954.016'], ['D03.383.606.515.200'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050....
['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]']
0
1
1
1
0
0
1
0
0
0
0
1
1
0
Effects of hydralazine on cardiac responsiveness to adrenergic agonists in streptozotocin-induced diabetic rats.
The present investigation was undertaken to study the effects of hydralazine treatment (50 mg/kg/day, p.o.) on methoxamine and isoproterenol-induced responses in cardiac preparations of control and streptozotocin (STZ)-induced diabetic rats. Triiodothyronine (T3) and thyroxine (T4) levels were found to be significantly...
['Adrenergic Agonists', 'Analysis of Variance', 'Animals', 'Atrial Function', 'Diabetes Mellitus, Experimental', 'Dose-Response Relationship, Drug', 'Female', 'Heart Atria', 'Heart Rate', 'Hydralazine', 'Isoproterenol', 'Methoxamine', 'Myocardial Contraction', 'Rats', 'Rats, Wistar', 'Thyroxine', 'Triiodothyronine']
7,906,674
[['D27.505.519.625.050.100', 'D27.505.696.577.050.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G09.330.040'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G07.690.773.875', 'G07.690.936.500'], ['A07.541.358'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D03....
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis.
BACKGROUND: Topical 5-aminolaevulinic acid (ALA)-photodynamic therapy (PDT) for the treatment of psoriasis has been evaluated in a few studies. In these studies different treatment parameters were used, there was a variable clinical response, and a nonhomogeneous fluorescence was seen after irradiation with Wood's ligh...
['Adult', 'Aminolevulinic Acid', 'Cell Differentiation', 'Cell Proliferation', 'Dose Fractionation, Radiation', 'Drug Administration Schedule', 'Epidermis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Photochemotherapy', 'Photosensitizing Agents', 'Protoporphyrins', 'Psoriasis', 'Severity of Illness Index', 'Skin', 'T-...
16,882,185
[['M01.060.116'], ['D02.241.755.547.276', 'D12.125.262'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['E02.815.639.200'], ['E02.319.283'], ['A10.272.497', 'A17.815.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.186.500', 'E02.319.685', 'E02.774.722'], ['D27.505.954.444.600'...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
1
1
0
Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
BACKGROUND: Several novel susceptibility loci for type 2 diabetes have been identified through genome-wide association studies (GWAS) for type 2 diabetes or quantitative traits related to glucose metabolism in European populations. To investigate the association of the 13 new European GWAS-derived susceptibility loci w...
['Case-Control Studies', 'Diabetes Mellitus, Type 2', 'European Continental Ancestry Group', 'Genetic Predisposition to Disease', 'Genome-Wide Association Study', 'Humans', 'Japan', 'Polymorphism, Single Nucleotide']
22,046,406
[['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750.149', 'C19.246.300'], ['M01.686.508.400'], ['C23.550.291.687.500', 'G05.380.355'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]']
0
1
1
0
1
0
1
0
0
0
0
1
1
1
Is the Inflammasome Pathway Active in the Peripheral Blood of Sulfur Mustard-exposed Patients?
The mustard lung is a late consequence of exposure to sulfur mustard (SM) in veterans who had participated in the Iraq-Iran war. Three mechanisms are contributed in the pathogenesis of mustard lung including oxidative stress, protease-antiprotease imbalance, and dysregulated immune response. In the context of the immun...
['Adaptor Proteins, Signal Transducing', 'Apoptosis Regulatory Proteins', 'Chemical Warfare Agents', 'Cross-Sectional Studies', 'Environmental Exposure', 'Female', 'Humans', 'Inflammasomes', 'Inflammation Mediators', 'Interleukin-1', 'Interleukin-18', 'Iraq War, 2003-2011', 'Lung Diseases', 'Male', 'Middle Aged', 'Must...
31,066,258
[['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.644.360.075', 'D12.776.476.075'], ['D27.720.777.300', 'D27.888.569.612.150', 'J01.637.870.900.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D0...
['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Named Groups [M]']
0
1
1
1
1
0
0
0
1
1
0
1
1
0
Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease.
Activated B cells function in antibody production and antigen presentation, but whether they perform any pathophysiological functions at sites of inflammation is not fully understood. Here, we report that intravenous injection of an agonistic anti-CD40 monoclonal antibody (alphaCD40) causes a biphasic inflammatory live...
['Animals', 'Antibodies, Monoclonal', 'B-Lymphocytes', 'CD40 Antigens', 'Hepatitis', 'Interferon-gamma', 'Liver', 'Lymphocyte Activation', 'Mice', 'Mice, SCID', 'Necrosis', 'Tumor Necrosis Factor-alpha']
16,507,894
[['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
1
1
1
0
1
0
0
0
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5-Aminolevulinic acid induced endogenous porphyrin fluorescence in 9L and C6 brain tumours and in the normal rat brain.
A new approach in photodynamic therapy is the use of endogenous porphyrins for sensitisation of tumours to light. The induction of endogenous porphyrins after intravenous injection of 5-aminolevulinic acid (ALA, 200 mg kg-1) was studied in 23 rats, bearing intracranial 9L or C6 tumours. After 0, 2, 4, 6, 8, and 22 hour...
['Aminolevulinic Acid', 'Animals', 'Brain', 'Brain Neoplasms', 'Disease Models, Animal', 'Glioma', 'Gliosarcoma', 'Male', 'Photosensitizing Agents', 'Porphyrins', 'Rats', 'Rats, Inbred Strains', 'Time Factors', 'Tumor Cells, Cultured']
9,728,253
[['D02.241.755.547.276', 'D12.125.262'], ['B01.050'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['C04.557.465.625.600.380.400', 'C04.557.470.670.380.400', '...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
Observer variation of 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography in mediastinal staging of non-small cell lung cancer as a function of experience, and its potential clinical impact.
PURPOSE: To test the extent of variation among nuclear medicine physicians with respect to staging non-small cell lung cancer with positron emission tomography (PET).PROCEDURES: Two groups of nuclear medicine physicians with different levels of PET experience reviewed 30 PET scans. They were requested to identify and l...
['Algorithms', 'Carcinoma, Non-Small-Cell Lung', 'Fluorine Radioisotopes', 'Fluorodeoxyglucose F18', 'Humans', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Mediastinal Neoplasms', 'Neoplasm Staging', 'Observer Variation', 'Positron-Emission Tomography', 'Radiopharmaceuticals']
17,610,119
[['G17.035', 'L01.224.050'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D01.496.749.340'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650.560', 'C23.550.727.650.560'], ['C04.588.894....
['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
1
1
1
0
1
0
0
0
1
0
1
0
The endogenous development, described by light and electron microscopy, of Eimeria jamescooki sp. n. (Apicomplexa: Eimeriidae) from the skink Cryptoblepharus virgatus.
Eimeria jamescooki sp. n. was recovered from the skink Cryptoblepharus virgatus (Garman) found on the grounds of James Cook University, Townsville (type locality), North Queensland, Australia. Oocysts were 17.5-25.0 (22.1 +/- 1.9) x 15-22.5 (17.7 +/- 1.6) microm and sporocysts 6.25-10.0 (7.9 +/- 1.15) x 3.75-6.25 (5.3 ...
['Animals', 'Australia', 'Coccidiosis', 'Eimeria', 'Feces', 'Life Cycle Stages', 'Lizards', 'Microscopy, Electron', 'Oocysts']
14,560,968
[['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['C01.610.752.250'], ['B01.043.075.189.250.250.250'], ['A12.459'], ['B05.500', 'G07.345.500.550.500'], ['B01.050.150.900.833.393'], ['E01.370.350.515.402', 'E05.595.402'], ['A11.870.740.600', 'B05.500.675', 'B05.775.740.600', 'G07.345.500.550.500.675']]
['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
0
1
0
0
0
0
0
0
1
IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6- and SOCS-1-dependent mechanisms.
IL-4 develops Th2-biased immunity or allergic inflammation through activation of STAT6-dependent signaling. In vascular endothelial cells (ECs), IL-4 elicits regulatory effects on chemokine production and adhesion molecule expression to recruit T cells and eosinophils. In this study, we examined how IL-4 affects Weibel...
['Endothelial Cells', 'Gene Expression Regulation', 'Humans', 'Interleukin-4', 'Organ Specificity', 'P-Selectin', 'STAT6 Transcription Factor', 'Suppressor of Cytokine Signaling 1 Protein', 'Suppressor of Cytokine Signaling Proteins', 'Weibel-Palade Bodies']
19,419,769
[['A11.436.275'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.186', 'D12.776.467.374.465.178', 'D23.529.374.465.186'], ['G07.650'], ['D12.776.395.550.200.700.775', 'D12.776.395.550.625.905', 'D12.776.503.843.775', 'D12.776.543.550.200.700.775', 'D12.776.543.550.625.905', 'D23.050...
['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease.
OBJECTIVES: Infliximab, an anti-tumor necrosis factor (TNF) monoclonal antibody, might exert some of its long-term therapeutic effects in Crohn's disease (CD) by interacting directly with cells of the immune system such as monocytes and T lymphocytes via membrane TNF and by inducing apoptosis. Accordingly, the effects ...
['Antibodies, Monoclonal', 'Apoptosis', 'Case-Control Studies', 'Crohn Disease', 'Gastrointestinal Agents', 'Humans', 'Infliximab', 'Monocytes', 'Tumor Necrosis Factor-alpha']
15,626,899
[['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.146.954.035'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['D27.505.954.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12....
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
Characterization of neuropeptides by reversed-phase, ion-pair liquid chromatography with post-column detection by radioimmunoassay. Application to thyrotropin-releasing hormone, substance P, and vasopressin.
Neuropeptide contents of rat brain samples were determined by radioimmunoassay (RIA) after fractionation of tissue extracts by high-performance liquid chromatography (HPLC). Solvent systems were composed of acetic acid, acetonitrile and short-chain (5--8 carbons) alkylsulfonic acids. Separate solvent systems were devel...
['Animals', 'Brain Chemistry', 'Chromatography, High Pressure Liquid', 'Corpus Striatum', 'Hypothalamus', 'Microchemistry', 'Pituitary Gland, Posterior', 'Radioimmunoassay', 'Rats', 'Spectrophotometry, Ultraviolet', 'Substance P', 'Thyrotropin-Releasing Hormone', 'Vasopressins']
6,164,686
[['B01.050'], ['G02.111.150', 'G03.185'], ['E05.196.181.400.300'], ['A08.186.211.200.885.287.249.487'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['E05.196.620', 'H01.181.650'], ['A06.300.747.875', 'A06.688.178.875', 'A06.688.357.750.875', 'A08.186.211.180.497.352.435.500.875', 'A08.186.211.200.317.357.352.43...
['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
1
0
0
0
0
0
0
Hydrochlorothiazide exerts no direct vasoactivity in the human forearm.
BACKGROUND: Recently, hydrochlorothiazide has been shown to relax vascular smooth muscle in vitro in clinically relevant concentrations by the opening of calcium-activated potassium channels, leading to hyperpolarization and consequent closing of voltage-operated calcium channels. Long-term administration of hydrochlor...
['Antihypertensive Agents', 'Brachial Artery', 'Forearm', 'Hemodynamics', 'Humans', 'Hydrochlorothiazide', 'Infusions, Intra-Arterial', 'Male', 'Plethysmography']
8,903,662
[['D27.505.954.411.162'], ['A07.015.114.139'], ['A01.378.800.585'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.590.700.135.261.476', 'D02.886.655.500.261.476', 'D03.633.100.174.261.476'], ['E02.319.267.510.520'], ['E01.370.370.610']]
['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Phospho-LAT-independent activation of the ras-mitogen-activated protein kinase pathway: a differential recruitment model of TCR partial agonist signaling.
Stimulation of mature T cells with agonist ligands of the Ag receptor (TCR) causes rapid phosphorylation of tyrosine-based activation motifs in the intracellular portion of TCR-zeta and CD3 and activation of several intracellular signaling cascades. Coordinate activation of these pathways is dependent on Lck- and ZAP-7...
['Adaptor Proteins, Signal Transducing', 'Animals', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Carrier Proteins', 'Clone Cells', 'Enzyme Activation', 'GRB2 Adaptor Protein', 'Lymphocyte Activation', 'Lymphocyte Specific Protein Tyrosine Kinase p56(lck)', 'Membrane Proteins', 'Mice', 'Models, Biological', 'Oligope...
10,438,919
[['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['D12.776.157'], ['A11.251.353'], ['G02.111.263', 'G03.328'], ['D12.644.360.024.290', 'D12.776.157.057.041', 'D12.776.476.024.377'], ['E01.370.225.812.482', 'E05.200.812.48...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Condom use and vaginal Y-chromosome detection: the specificity of a potential biomarker.
OBJECTIVE: Detection of vaginal Y-chromosome sequences (YCS) may be a useful biomarker to validate sexual behavior reporting in women. We describe the effects of condom use on the detection of vaginal YCS.METHODS: Fifty-six women were asked to abstain from sexual intercourse for 14 days. On day 15, participants were as...
['Biomarkers', 'Chromosomes, Human, Y', 'Condoms', 'DNA', 'Female', 'Humans', 'Male', 'Polymerase Chain Reaction', 'Predictive Value of Tests', 'Semen', 'Sensitivity and Specificity', 'Sexually Transmitted Diseases', 'Vaginal Smears']
17,308,500
[['D23.101'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['E07.190.270.150'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], [...
['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
Gambling-related attitudes and behaviors in adolescents having received instant (scratch) lottery tickets as gifts.
OBJECTIVE: Instant (scratch) lottery ticket gambling is popular among adolescents. Prior research has not determined whether adolescents' gambling behavior and attitudes toward gambling are influenced by the receipt of scratch lottery tickets as gifts.METHOD: Cross-sectional survey data from 2,002 Connecticut high scho...
['Attitude', 'Connecticut', 'Cross-Sectional Studies', 'Female', 'Gambling', 'Gift Giving', 'Humans', 'Leisure Activities', 'Male', 'Motivation', 'Psychology, Adolescent', 'Risk', 'Social Facilitation']
23,299,004
[['F01.100'], ['Z01.107.567.875.550.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.722.408', 'F03.250.400'], ['F01.145.813.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.450'], ['F01.658', 'F01.752.543.500.750'], ['F04.096.628.065'], ['E05.318.740.600.800'...
['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]']
0
1
0
0
1
1
1
0
1
0
0
0
1
1
Early detection of type 2 diabetes: the role of the community nurse.
Recent changes to the diagnostic criteria for type 2 diabetes have raised concerns that if steps are not taken to address relevant issues, the number of diagnosed sufferers will escalate in future years, with a similar increase in the prevalence of associated complications. Research suggests that for many patients, com...
['Community Health Nursing', 'Diabetes Mellitus, Type 2', 'Humans', "Nurse's Role", 'Nursing Diagnosis', 'Risk Factors']
11,907,442
[['H02.478.676.150', 'N02.421.143.150'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['N04.590.233.508.480.110'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850...
['Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
1
0
1
0
0
0
0
1
0
Infant salt preference and mother's morning sickness.
Evidence for an association between early pregnancy sickness and offspring salt (NaCl) preference has been obtained from studying offspring as young adults. To determine whether effects on NaCl preference are expressed in infancy, the present study examined 16-week-old infants whose mothers reported either little or no...
['Adult', 'Female', 'Food Preferences', 'Humans', 'Infant', 'Pregnancy', 'Pregnancy Complications', 'Sodium Chloride, Dietary', 'Vomiting']
9,632,460
[['M01.060.116'], ['F01.145.407.516', 'G07.203.650.353.516'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G08.686.784.769'], ['C13.703'], ['D01.857.650.705', 'D01.857.875.705'], ['C23.888.821.937']]
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]']
0
1
1
1
0
1
1
0
0
0
0
1
0
0
Perilymph fistula.
Perilymph fistula occurs when endolymph and perilymph mix, or when perilymph leaks into the middle ear space. Sensorineural hearing loss and/or vertigo may result. This paper reviews the pertinent anatomy and physiology of the inner ear, clinical presentations, diagnosis, treatment, and prognosis as a guide for the cli...
['Adult', 'Athletic Injuries', 'Audiometry', 'Child', 'Female', 'Fistula', 'Hearing Loss', 'Hearing Loss, Sensorineural', 'Humans', 'Labyrinth Diseases', 'Labyrinthine Fluids', 'Male', 'Middle Aged', 'Perilymph', 'Prognosis', 'Vertigo']
4,071,174
[['M01.060.116'], ['C26.115'], ['E01.370.382.375.060'], ['M01.060.406'], ['C23.300.575'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.568'], ['A09.246....
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
0
0
1
0
0
Missense mutations in the beta(3) subunit have a different impact on the expression and function between alpha(IIb)beta(3) and alpha(v)beta(3).
Alpha(IIb)beta(3) and alpha(v)beta(3) belong to the beta(3) integrin subfamily. Although the beta(3) subunit is a key regulator for the biosynthesis of beta(3) integrins, it remains obscure whether missense mutations in beta(3) may induce the same defects in both alpha(IIb)beta(3) and alpha(v)beta(3). In this study, it...
['Adult', 'Amino Acid Sequence', 'Antigens, CD', 'Blood Platelets', 'Cell Line', 'DNA Mutational Analysis', 'Female', 'Fibrinogen', 'Gene Expression', 'Humans', 'Integrin beta3', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Mutation, Missense', 'Platelet Glycoprotein GPIIb-IIIa Complex', 'Platelet Membrane...
11,806,996
[['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.118.188', 'A15.145.229.188'], ['A11.251.210'], ['E05.393.760.700.300'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400...
['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]']
1
1
1
1
1
0
1
0
0
0
1
1
0
0
Juniper tar (cade oil) poisoning in new born after a cutaneous application.
Juniper tar (cade oil) is distilled from the branches and wood of Juniperus oxycedrus. It contains etheric oils, triterpene and phenols, used for many purposes in folk medicine. The authors report a case of a previously healthy new born treated with a topical application of Juniperus oxycedrus for atopic dermatosis The...
['Acute Kidney Injury', 'Administration, Cutaneous', 'Chemical and Drug Induced Liver Injury', 'Dermatitis, Atopic', 'Humans', 'Infant, Newborn', 'Plant Extracts', 'Pulmonary Edema', 'Seizures', 'Skin Absorption', 'Tars']
22,675,090
[['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['E02.319.267.120.060'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D20.215.784.500', 'D26.667...
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
0
0
1
0
0
Effects of unilateral PEEP on biomechanics of both lungs during independent lung ventilation in patients anaesthetised for thoracic surgery.
BACKGROUND: Synchronous independent lung ventilation (ILV) is the treatment of choice for unilateral pathology of lung parenchyma. Numerous studies have documented the improved blood oxygenation and clinical efficacy of this procedure. The aim of the present study was to evaluate the effects of ILV on the selected biom...
['Adult', 'Airway Resistance', 'Anesthesia, General', 'Biomechanical Phenomena', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Positive-Pressure Respiration', 'Respiration, Artificial', 'Thoracic Surgical Procedures', 'Tidal Volume']
25,751,288
[['M01.060.116'], ['E01.370.386.700.050', 'G09.772.060'], ['E03.155.197'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['E02.041.625.790', 'E02.880.820.790'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['E04.928'], ['E01.370.386.700.485.750....
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]']
1
1
0
0
1
0
1
0
0
0
0
1
0
0
The status of psychiatric nursing: characteristics and perceptions of nurses in the state of Michigan.
Concerned about the status of both mental health services and the role of professional nursing in the delivery of those services, the Michigan Nurses' Association Psychiatric-Mental Health Nursing Practice Section initiated a survey of psychiatric nurses in the state. One hundred forty psychiatric nurses returned quest...
['Adult', 'Aged', 'Attitude of Health Personnel', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Mental Health Services', 'Michigan', 'Middle Aged', 'Nurses', 'Psychiatric Nursing', 'Surveys and Questionnaires']
7,558,792
[['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.408', 'N02.421.461'], ['Z01.107.567.875.350.500', 'Z01.107.567.875.510.500'], ['M01.060.116.630'], ['M01.526.485.650', 'N02.360.650'], ['H02.478.676.710',...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
0
1
1
0
1
0
0
0
1
1
1
A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design.
We present the systematic prospective evaluation of a protein-based and a ligand-based virtual screening platform against a set of three G-protein-coupled receptors (GPCRs): the â-2 adrenoreceptor (ADRB2), the adenosine A(2A) receptor (AA2AR), and the sphingosine 1-phosphate receptor (S1PR1). Novel bioactive compounds ...
['Adenosine A2 Receptor Agonists', 'Adenosine A2 Receptor Antagonists', 'Adrenergic beta-2 Receptor Agonists', 'Adrenergic beta-2 Receptor Antagonists', 'Animals', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Databases, Factual', 'Drug Design', 'Drug Partial Agonism', 'HEK293 Cells', 'High-Throughput Screening Assays', 'H...
22,563,707
[['D27.505.519.625.725.200.100.200', 'D27.505.696.577.725.200.100.200'], ['D27.505.519.625.725.400.100.200', 'D27.505.696.577.725.400.100.200'], ['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['D27.505.519.625.050.200.200.200', 'D27.505.696.577.050.200.200.200'], ['B01.050'], ['A11.251.210.200'...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
0
1
1
0
1
1
0
0
1
0
1
0
Treatment of a Fetal Tracheal Obstruction by Fetoscopy and Laser.
We report below a case of in utero tracheoscopy with laser collapse of a bronchogenic cyst obstructing the fetal trachea. The patient was referred for ultrasonography at 24 weeks of gestation because of fetal hydrops. Tracheoscopy was performed via fetoscopic approach using a single trocar under local anesthesia with l...
['Adult', 'Airway Obstruction', 'Female', 'Fetoscopy', 'Humans', 'Mediastinal Cyst', 'Pregnancy', 'Ultrasonography, Prenatal']
25,660,567
[['M01.060.116'], ['C08.618.846.185'], ['E01.370.378.630.300', 'E01.370.388.250.280', 'E02.467.750', 'E04.502.250.280', 'E04.520.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.182.444', 'C08.846.187.145'], ['G08.686.784.769'], ['E01.370.350.850.865', 'E01.370.378.630.865']]
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
1
0
1
0
1
0
0
0
0
1
0
0
E-Health, another mechanism to recruit and retain healthcare professionals in remote areas: lessons learned from EQUI-ResHuS project in Mali.
BACKGROUND: The aim of this study was to evaluate the perceived influence of telehealth on recruitment and retention of healthcare professionals in remote areas in Mali.METHODS: After 15 months of diagnosis imaging training and telehealth activities at four project sites in remote Mali, between May 2011 and August 2012...
['Adult', 'Attitude of Health Personnel', 'Computer Communication Networks', 'Education, Continuing', 'Education, Distance', 'Evaluation Studies as Topic', 'Female', 'Health Care Surveys', 'Health Personnel', 'Humans', 'Job Satisfaction', 'Male', 'Mali', 'Middle Aged', 'Personnel Selection', 'Pilot Projects', 'Regressi...
25,539,841
[['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['L01.224.230.110'], ['I02.358.212'], ['I02.195'], ['E05.337', 'N05.715.360.335'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]']
0
1
0
0
1
1
0
1
1
0
1
1
1
1
Transcatheter coil embolization of abnormal vascular connections using a new type of delivery catheter for enhanced control.
A new type of delivery catheter, designed with a 0.033-inch distal tip that grips a 0.038-inch Gianturco coil, was used to occlude 61 abnormal vascular connections in 44 patients with a complete closure rate of 87%. Withdrawal (n = 6) or repositioning (n = 2) of an inappropriately positioned coil was necessary in 8 of ...
['Arteriovenous Fistula', 'Arteriovenous Malformations', 'Catheterization', 'Embolization, Therapeutic', 'Humans']
10,190,426
[['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['E02.148', 'E05.157'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400']]
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
1
0
1
0
0
0
0
0
0
0
0
0
[Benign tumors of the spine in the adolescent. Surgical considerations apropos of 4 cases].
About 4 observations of benign tumours of the spine of the adolescent, we have studied the surgical aspect of the treatment of these lesion. The choice of the surgical approach is fundamental in view of the necessity of a complete exeresis, which implies techniques of spinal reconstruction and stabilization. Those prob...
['Adolescent', 'Bone Cysts', 'Cervical Vertebrae', 'Child', 'Chondroma', 'Eosinophilic Granuloma', 'Female', 'Humans', 'Laminectomy', 'Lumbar Vertebrae', 'Male', 'Spinal Neoplasms', 'Thoracic Vertebrae']
3,366,821
[['M01.060.057'], ['C04.182.089', 'C05.116.070'], ['A02.835.232.834.151'], ['M01.060.406'], ['C04.557.450.565.265'], ['C05.116.391', 'C08.381.483.375.500', 'C15.378.553.231.348', 'C15.604.250.400.360', 'C23.550.382.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E0...
['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
0
0
0
0
0
0
1
0
0
Quality of Blood Pressure Tracking Apps for the iPhone: Content Analysis and Evaluation of Adherence With Home Blood Pressure Measurement Best Practices.
BACKGROUND: Blood pressure (BP) tracking apps may aid in hypertension (HTN) self-management, but app quality may be problematic.OBJECTIVE: This study aimed to develop a content-dependent rating system for BP tracking apps and systematically evaluate BP tracking features, content-independent quality, functional characte...
['Blood Pressure', 'Blood Pressure Determination', 'Canada', 'Equipment Design', 'Humans', 'Practice Guidelines as Topic', 'Self-Management', 'Technology Assessment, Biomedical']
30,977,739
[['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['Z01.107.567.176'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['N02.421.784.760'], ['N03.880', 'N05.715.360.825']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]']
0
1
0
0
1
0
1
0
0
0
0
0
1
1
Ecdysteroid-regulated heat-shock gene expression during Drosophila melanogaster development.
Peaks in hsp 26, 28, and 83 RNA levels are correlated with peaks in ecdysteroid titers during mid-embryogenesis, pupariation, and mid-pupation, and with a peak in the level of RNA from the 74EF ecdysone puff at pupariation. Inhibition of the ecdysteroid peak at pupariation by temperature shift of the conditionally ecdy...
['Animals', 'Drosophila melanogaster', 'Ecdysterone', 'Genes', 'Heat-Shock Proteins', 'Juvenile Hormones', 'Mutation']
3,086,161
[['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D04.210.500.247.222.265.165.750', 'D06.472.445.573.271.750'], ['G05.360.340.024.340'], ['D12.776.580.216'], ['D06.472.445.573.666'], ['G05.365.590']]
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
0
1
0
1
0
0
1
0
0
0
0
0
0
0
[A study of factors related to activities of daily living (ADL) of the elderly receiving in-home service longitudinal study using functional independence measures].
OBJECTIVE: We conducted a longitudinal study using Functional Independence Measures to clarify factor related to independence of activities of daily living of elderly receiving in-home service under the long-term care insurance systemMETHODS: Fifty-four elderly users of the in-home service of Ibaraki Prefecture assente...
['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Community Health Nursing', 'Female', 'Geriatric Assessment', 'Health Services for the Aged', 'Home Care Services', 'Humans', 'Insurance, Long-Term Care', 'Longitudinal Studies', 'Male']
17,419,402
[['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['H02.478.676.150', 'N02.421.143.150'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['N02.421.320'], ['N02.421....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]']
0
1
0
0
1
0
0
1
1
0
0
1
1
0
Protective effect of butylated hydroxytoluene on ferric nitrilotriacetate induced hepatotoxicity and oxidative stress in mice.
The present study was undertaken to evaluate the possible ameliorating effect of butylated hydroxyl toluene (BHT), associated with ferric nitrilotriacetate (Fe-NTA)-induced oxidative stress and liver injury in mice. The treatment of mice with Fe-NTA alone enhances ornithine decarboxylase activity to 4.6 folds, protein ...
['Animals', 'Butylated Hydroxytoluene', 'Enzyme Induction', 'Ferric Compounds', 'Lipid Peroxidation', 'Liver', 'Male', 'Mice', 'Nitrilotriacetic Acid', 'Ornithine Decarboxylase', 'Oxidative Stress', 'Protein Carbonylation']
23,444,334
[['B01.050'], ['D02.455.426.559.389.657.239.216'], ['G05.308.320.200'], ['D01.490.100'], ['G02.111.515', 'G03.295.531.587'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.241.081.018.588'], ['D08.811.520.224.125.425'], ['G03.673', 'G07.775.750'], ['G02.111.660.871.790.600.350', 'G02.111.691.600.350', ...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Metabolism of thyrotropin releasing hormone in brain extracts. Isolation and characterization of an imidopeptidase for histidylprolineamide.
An extract of porcine brain acetone powder incubated with thyrotropin-releasing hormone (TRH; pGlu-His-ProNH2) produces acid TRH (pGlu-His-Pro), histidine, and prolineamide. Fractionation of the brain extract by DEAE-cellulose chromatography produces three protein fractions which metabolize TRH. The activity of these f...
['Animals', 'Brain', 'Dipeptidases', 'Dipeptides', 'Histidine', 'Kinetics', 'Proline', 'Thyrotropin-Releasing Hormone']
107,159
[]
[]
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Opposing effects of circadian clock genes bmal1 and period2 in regulation of VEGF-dependent angiogenesis in developing zebrafish.
Molecular mechanisms underlying circadian-regulated physiological processes remain largely unknown. Here, we show that disruption of the circadian clock by both constant exposure to light and genetic manipulation of key genes in zebrafish led to impaired developmental angiogenesis. A bmal1-specific morpholino inhibited...
['ARNTL Transcription Factors', 'Animals', 'Animals, Genetically Modified', 'Neovascularization, Physiologic', 'Period Circadian Proteins', 'Response Elements', 'Vascular Endothelial Growth Factor A', 'Zebrafish', 'Zebrafish Proteins']
22,884,368
[['D12.644.360.138.049', 'D12.776.260.103.249', 'D12.776.476.156.100', 'D12.776.930.125.249'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G09.330.630'], ['D12.644.360.138.575', 'D12.776.157.530.750.687', 'D12.776.476.156.625', 'D12.776.543.585.750.687'], ['G02.111.570.080.689.330.700', 'G02.111.570.080.689.675....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
0
1
0
0
1
0
0
0
0
0
0
0
Development of an absorbance-based response model for monitoring the growth rates of Arcobacter butzleri as a function of temperature, pH, and NaCl concentration.
In this study, the growth of Arcobacter butzleri in poultry was evaluated as a function of storage temperature (5, 22.5, and 40°C), pH (5, 7, and 9), and NaCl concentration (0, 4, and 8%). A predictive model was developed using the absorbance-based response surface methodology to describe the growth rate. The primary m...
['Absorption, Physiological', 'Animals', 'Arcobacter', 'Hydrogen-Ion Concentration', 'Models, Biological', 'Poultry', 'Sodium Chloride', 'Temperature']
25,577,800
[['G03.015.500', 'G03.787.024.500', 'G07.690.725.015.500'], ['B01.050'], ['B03.440.050', 'B03.660.150.050'], ['G02.300'], ['E05.599.395'], ['B01.050.050.116.625', 'B01.050.150.900.248.690', 'G07.203.300.600.750', 'J02.500.600.750'], ['D01.210.450.150.875', 'D01.857.650'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16...
['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]']
0
1
0
1
1
0
1
0
0
1
0
0
1
0
Hormonal modulation of prolyl endopeptidase and dipeptidyl peptidase IV activities in the mouse uterus and ovary.
Prolyl endopeptidase and dipeptidyl peptidase IV are proline-specific peptidases, and are ubiquitously distributed in various tissues in mammals. The specific activities of these peptidases in both uterus and ovary were examined in the SHN strain of mice at estrus or diestrus. A marked change in prolyl endopeptidase ac...
['Animals', 'Dipeptidyl Peptidase 4', 'Dipeptidyl-Peptidases and Tripeptidyl-Peptidases', 'Estradiol', 'Estrus', 'Female', 'Hormones', 'Mice', 'Mice, Inbred Strains', 'Ovariectomy', 'Ovary', 'Perphenazine', 'Progesterone', 'Prolyl Oligopeptidases', 'Serine Endopeptidases', 'Uterus']
1,357,903
[['B01.050'], ['D08.811.277.656.350.350.126', 'D08.811.277.656.959.250', 'D23.050.301.264.894.160', 'D23.101.100.894.160'], ['D08.811.277.656.350.350'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Interaction between interleukin-1 and ciliary neurotrophic factor in the regulation of neuroblastoma cell functions.
Human neuroblastoma cells SK-N-SH express significant numbers of IL-1R type I on their surface, as detected by saturation binding and RT-PCR, and are responsive to IL-1beta activation by producing inflammatory cytokines IL-6 and IL-8. IL-1beta can also have an indirect effect on nervous cell functions, since it is able...
['Ciliary Neurotrophic Factor', 'Down-Regulation', 'Humans', 'Inflammation', 'Interleukin-1', 'Nerve Tissue Proteins', 'Neuroblastoma', 'Neurons', 'Polymerase Chain Reaction', 'Receptors, Interleukin-1', 'Transcription, Genetic']
9,459,616
[['D12.644.276.860.212', 'D12.776.467.860.212', 'D12.776.631.600.212', 'D23.529.850.212'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D2...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
Intra-axonal ferric ion-ferrocyanide staining of nodes of Ranvier and initial segments in central myelinated fibers.
Ferric ion and ferrocyanide were used to stain central nervous tissue from the spinal cords of rats following fixation in cacodylate-buffered aldehydes. At the nodes of Ranvier in myelinated fibers, the stain was localized primarily on the inner surface of the unmyelinated nodal axolemma, as had been reported previousl...
['Animals', 'Axons', 'Ferric Compounds', 'Ferrocyanides', 'Myelin Sheath', 'Nerve Fibers, Myelinated', 'Neurilemma', "Ranvier's Nodes", 'Rats', 'Spinal Cord', 'Staining and Labeling']
76,497
[['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D01.490.100'], ['D01.248.497.158.291.370', 'D01.490.200.250', 'D01.625.400.100.350'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149.165.600', 'A11.650.600.500', 'A...
['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
0
0
0
0
0
0
0
0
Bioinformatics Analysis of Stromal Molecular Signatures Associated with Breast and Prostate Cancer.
This study aimed to identify stromal molecular signatures associated with breast and prostate cancer. The microarray data GSE26910 was downloaded from Gene Expression Omnibus database, including six invasive breast tumor stroma, six matched normal controls, six invasive prostate tumor stroma, and six matched controls. ...
['Biomarkers, Tumor', 'Breast Neoplasms', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Gene Ontology', 'Gene Regulatory Networks', 'Genomics', 'Glutathione Transferase', 'Humans', 'Male', 'Neoplasm Invasiveness', 'Plakins', 'Prostatic Neoplasms', 'Protein Interaction Maps', 'Recepto...
31,180,245
[['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['E05.393.332'], ['G05.308.370'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['G05.360.080.689.360'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['D08.811....
['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]']
0
1
1
1
1
0
1
1
0
0
1
0
0
0
Separate pathways for p53 induction by ionizing radiation and N-(phosphonoacetyl)-L-aspartate.
The tumor suppressor gene product, p53, appears to be a significant participant in signaling pathways that mediate cellular responses to cytotoxic stresses. In particular, p53 appears to be a critical determinant of whether the cell lives or dies and how it progresses through the cell cycle after the cytotoxic exposure...
['Antimetabolites, Antineoplastic', 'Aspartic Acid', 'Base Sequence', 'Cell Cycle', 'Cell Line', 'DNA Damage', 'Gene Expression Regulation', 'Genes, p53', 'Humans', 'Molecular Sequence Data', 'Phosphonoacetic Acid', 'Tumor Suppressor Protein p53']
8,706,003
[['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144'], ['A11.251.210'], ['G05.200'], ['G05.308'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
1
0
0
1
0
0
0
1
0
0
0
Safety of 9.3-GHz microwave radiant heating for possible caloric supplement and medical treatment.
The hematological and blood-chemistry effects of chronic microwave radiation on unrestrained rhesus monkeys trained to expose their face and eyes to 9.3GHz microwave radiation at an average incident power density of 150 or 300mW/cm2 are reported. Only inconsistent transient effects were found. The lack of significant h...
['Animals', 'Blood', 'Heating', 'Macaca mulatta', 'Microwaves']
3,847,503
[['B01.050'], ['A12.207.152', 'A15.145'], ['N06.230.150.300'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500']]
['Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]']
1
1
0
0
0
0
1
0
0
0
0
0
1
0
Indolent T-lymphoblastic proliferation: report of a case with an 11-year history and association with myasthenia gravis.
T-lymphoblastic lymphoma is a high-grade malignant lymphoma with frequent occurrence in young males, mediastinal involvement, and systemic dissemination. Indolent T-lymphoblastic proliferations have rarely been recognized. In the present case, we report on an indolent T-lymphoblastic proliferation involving the orophar...
['Adult', 'Antigens, CD', 'Antigens, Neoplasm', 'DNA Nucleotidylexotransferase', 'DNA, Neoplasm', 'Humans', 'Immunoenzyme Techniques', 'Immunophenotyping', 'Lymph Nodes', 'Male', 'Myasthenia Gravis', 'Oropharynx', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma']
11,224,614
[['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.285'], ['D08.811.913.696.445.308.325'], ['D13.444.308.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['A10.549.400', ...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]']
1
1
1
1
1
0
0
0
0
0
0
1
0
0
A comparison of four tests for assessing the pain sensitivity of different subjects and test areas.
Four different testing methods were used to estimate the sensitivity of body surfaces to pain-causing stimuli for a group of 24 healthy male subjects. These methods were (a) determination of the heat pain threshold, (b) determination of the pain threshold for pinching of a skin fold, (c) discrimination of a sharp prick...
['Abdomen', 'Cold Temperature', 'Hot Temperature', 'Humans', 'Male', 'Neck', 'Nociceptors', 'Pain', 'Physical Stimulation', 'Skin', 'Stress, Mechanical', 'Thigh']
909,713
[['A01.923.047'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.98...
['Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
1
1
0
0
0
0
0
1
0
Lesional infiltration of receptor activator of nuclear factor-êB ligand⁺ cells in experimental autoimmune neuritis rats.
Experimental autoimmune neuritis (EAN) is a T cell-mediated autoimmune demyelinating inflammatory disease of the peripheral nervous system. Receptor activator of NF-êB ligand (RANKL), a member of the tumor necrosis factor family, regulates proliferation of mature T cells. Here, we have studied the expression of RANKL i...
['Analysis of Variance', 'Animals', 'Antigens, CD', 'B-Lymphocytes', 'Cell Count', 'Disease Models, Animal', 'Encephalomyelitis, Autoimmune, Experimental', "Freund's Adjuvant", 'Macrophages', 'Male', 'Microglia', 'Neutrophil Infiltration', 'Oligopeptides', 'Rats', 'Rats, Inbred Lew', 'Receptor Activator of Nuclear Fact...
22,810,119
[['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C2...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
Cost-effectiveness analysis of different rescue therapies in patients with lamivudine-resistant chronic hepatitis B in China.
BACKGROUND: Several rescue therapies have been used in patients with lamivudine (LAM)-resistant chronic hepatitis B (CHB); however, the economic outcome of these therapies is unclear. The object of the current analysis was to evaluate the lifetime cost-effectiveness of rescue therapies among patients with LAM-resistant...
['Adult', 'Antiviral Agents', 'China', 'Cohort Studies', 'Cost-Benefit Analysis', 'Drug Resistance, Viral', 'Drug Therapy, Combination', 'Emergency Treatment', 'Female', 'Hepatitis B e Antigens', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Lamivudine', 'Male', 'Markov Chains', 'Organophosphonates', 'Patient...
23,137,013
[['M01.060.116'], ['D27.505.954.122.388'], ['Z01.252.474.164'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N03.219.151.125'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['E02.319.310'], ['E02.365'], ['D23.050.327.495.500.469'], ['B04.280.375.650.425', 'B04.450.390.6...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
0
1
1
1
1
0
1
0
1
0
0
1
1
1
Synthesis and analysis of a fluorinated product analogue as an inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
1-deoxy-D-xylulose 5-phosphate (DXP) reductoisomerase (DXR) is an NADPH-dependent enzyme catalyzing the rearrangement and reduction of DXP to methyl-D-erythritol 4-phosphate (MEP). Two mechanisms for this enzymatic reaction have been proposed, involving either an alpha-ketol rearrangement or a retroaldol/aldol rearrang...
['Aldose-Ketose Isomerases', 'Enzyme Inhibitors', 'Erythritol', 'Molecular Structure', 'Multienzyme Complexes', 'Oxidation-Reduction', 'Oxidoreductases']
18,078,746
[['D08.811.399.475.200'], ['D27.505.519.389'], ['D02.033.800.329', 'D09.853.329'], ['G02.111.570', 'G02.466'], ['D05.500.562', 'D08.811.600'], ['G02.700', 'G03.295.531'], ['D08.811.682']]
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
0
0
0
1
0
0
1
0
0
0
0
0
0
0
Fast activated charcoal prepurification of Fusarium solani â-glucosidase for an efficient oleuropein bioconversion.
Fungal â-glucosidases were extensively studied regarding their various potential biotechnology applications. Here, we report the selection of Fusarium solani strain producing high yield of â-glucosidase activity. The effect of some factors on â-glucosidase production was studied including: Initial pH, medium compositio...
['Charcoal', 'Culture Media', 'Fusarium', 'Hydrogen-Ion Concentration', 'Iridoids', 'beta-Glucosidase']
27,340,756
[['D01.268.150.150'], ['D27.720.470.305', 'E07.206'], ['B01.300.381.366'], ['G02.300'], ['D02.455.426.392.368.450.675.500', 'D02.455.849.575.188.500', 'D03.383.663.491'], ['D08.811.277.450.420.200.100']]
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Oxacillin-susceptible methicillin-resistant Staphylococcus aureus (OS-MRSA), a hidden resistant mechanism among clinically significant isolates in the Wessex region/UK.
PURPOSE: Methicillin-resistant Staphylococcus aureus (MRSA) is defined as S. aureus genetically having the mecA or mecC genes or phenotypically showing minimum inhibitory concentration (MIC) of oxacillin higher than 2 mg/L. However, recently, cefoxitin/oxacillin-susceptible mecA-positive S. aureus (OS-MRSA) has been re...
['Anti-Bacterial Agents', 'Bacterial Proteins', 'Bacterial Toxins', 'Drug Resistance, Multiple, Bacterial', 'Electrophoresis, Gel, Pulsed-Field', 'England', 'Exotoxins', 'Humans', 'Leukocidins', 'Methicillin', 'Methicillin-Resistant Staphylococcus aureus', 'Oxacillin', 'Penicillin-Binding Proteins', 'Prevalence', 'Stap...
24,919,530
[['D27.505.954.122.085'], ['D12.776.097'], ['D23.946.123'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['E05.196.401.220', 'E05.301.300.220'], ['Z01.542.363.300'], ['D23.946.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.695.750'], ['D02.065....
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]']
0
1
1
1
1
0
1
0
0
0
0
0
1
1
Sericin improves heart and liver mitochondrial architecture in hypercholesterolaemic rats and maintains pancreatic and adrenal cell biosynthesis.
Hypercholesterolaemia is well known to be associated with mitochondrial dysfunction, subsequently leading to multiple organ failure. Similar to other natural products, sericin is a candidate for adjunctive therapy in hyperlipidaemic conditions. However, the cholesterol-lowering mechanisms of sericin are multifactorial ...
['Animals', 'Antioxidants', 'Cells, Cultured', 'Cholesterol', 'Heart', 'Hypercholesterolemia', 'Liver', 'Mitochondria', 'Oxidative Stress', 'Pancreas', 'Rats, Sprague-Dawley', 'Sericins', 'Triglycerides', 'Up-Regulation']
28,684,113
[['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A11.251'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['A07.541'], ['C18.452.584.500.500.396'], ['A03.620'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G03.673', 'G07.775.750'], ['A03.734'], ['B01.0...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Primary signet-ring cell carcinoma of the urinary bladder.
Sixty-one cases of adenocarcinoma of the urinary bladder presenting between 1966 and 1981 were reviewed. Among the only seven cases of primary adenocarcinoma of the urinary bladder, three were classified as primary signet-ring cell carcinoma. These 3 cases were reviewed with the 11 previously reported cases in the lite...
['Adenocarcinoma', 'Adenocarcinoma, Mucinous', 'Adult', 'Aged', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged', 'Urinary Bladder Neoplasms']
6,322,967
[['C04.557.470.200.025'], ['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707']]
['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
1
0
1
0
0
0
0
0
0
1
0
0
Virulence factors of uropathogenic Escherichia coli of urinary tract infections and asymptomatic bacteriuria in children.
BACKGROUND/PURPOSE: The clinical aspects of virulence genes of uropathogenic Escherichia coli (UPEC) are not fully understood. This study compared the presence of virulence genes in UPEC isolated from urinary tract infections (UTIs) and asymptomatic bacteriuria (ABU) in children.METHODS: The study included children wit...
['Bacteriuria', 'Child', 'Child, Preschool', 'DNA, Bacterial', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Female', 'Hospitals', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Microbial Sensitivity Tests', 'Polymerase Chain Reaction', 'Republic of Korea', 'Urinary Tract Infections', 'Uropathogenic Esc...
24,064,288
[['C01.915.219', 'C12.777.892.219', 'C13.351.968.892.219'], ['M01.060.406'], ['M01.060.406.448'], ['D13.444.308.212'], ['C01.150.252.400.310.330'], ['D12.776.097.275'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05...
['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]']
0
1
1
1
1
0
0
0
0
0
0
1
1
1
Influence of certain clinical variables on black preschoolers' nonstandard phonological and grammatical performance.
The influence of socioeconomic background, sex, and clinicians' race on the frequency of implementation of nonstandard phonological and grammatical structures was examined in 72 black preschoolers. In order to generalize findings to typical clinical settings, language samples were elicited by 3 black and 3 white clinic...
['African Americans', 'Child, Preschool', 'Female', 'Humans', 'Language Disorders', 'Male', 'Phonetics', 'Sex Factors', 'Socioeconomic Factors', 'Verbal Behavior', 'Verbal Learning']
802,978
[['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.500', 'C23.888.592.604.150.500'], ['L01.559.598.518'], ['N05.715.350.675', 'N06.850.490.875'], ['I01.880.853.996', 'N01.824'], ['F01.145.209.908'], ['F02.463.425.952']]
['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]']
0
1
1
0
0
1
0
0
1
0
1
1
1
0
Characterization of the hydrogen peroxide-enzyme reaction for two cytochrome c peroxidase mutants.
The bimolecular reaction between Escherichia coli-produced cytochrome-c peroxidase (CcP(MI)) and hydrogen peroxide is identical to that of native yeast cytochrome-c peroxidase (CcP) and hydrogen peroxide in the neutral pH region. Both enzymes have pH-independent bimolecular rate constants of 46 microM-1.s-1 for the rea...
['Cytochrome-c Peroxidase', 'Escherichia coli', 'Free Radicals', 'Hydrogen Peroxide', 'Hydrogen-Ion Concentration', 'Kinetics', 'Mutation', 'Peroxidases', 'Saccharomyces cerevisiae', 'Spectrum Analysis', 'Structure-Activity Relationship']
2,156,573
[['D08.811.682.732.380'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.339', 'D02.389'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['G05.365.590'], ['D08.811.682.732'], ['B01.300.107.795.785.800', 'B01....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
[The hypophysis and haemoblastoses].
In necropsies of 165 patients with malignant haemoblastoses, infiltrates in the pituitary were found in 38 cases (23%). The most frequent occurrence was found in lymphoblastic leucosis (33.3%) and in non-Hodgkin lymphomas (29%). Hypophyseal manifestations were found in 21% for myoblastic leucosis and in 5.5% in case of...
['Hodgkin Disease', 'Humans', 'Leukemia, Lymphoid', 'Leukemia, Myeloid, Acute', 'Lymphoma', 'Lymphoma, Large B-Cell, Diffuse', 'Pituitary Gland', 'Pituitary Neoplasms']
384,729
[]
[]
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Effect of FK 506 and lipo prostaglandin E1 on heart allograft survival in rats.
FK 506 (FK) has a strong immunosuppressive effect, but a low-grade, dose-dependent nephrotoxicity and diabetogenicity, which means that reducing the dose of FK is of considerable interest. Lipo-prostaglandin E1 (LPGE1) is a preparation of PGE1 that has potent immunosuppressive properties, and its duration of action is ...
['Alprostadil', 'Animals', 'Delayed-Action Preparations', 'Disease Models, Animal', 'Drug Therapy, Combination', 'Female', 'Graft Rejection', 'Graft Survival', 'Heart Transplantation', 'Immunosuppressive Agents', 'Injections, Intramuscular', 'Male', 'Rats', 'Rats, Inbred Strains', 'Tacrolimus', 'Transplantation, Homolo...
10,622,549
[['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['D26.255.210', 'E02.319.300.253'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.310'], ['G12.875.545.328'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['D27.505.696.477....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]']
0
1
1
1
1
0
1
0
0
0
0
0
1
0
Laparoscopic wedge resection of gastric leiomyoma.
Gastric leiomyoma is a relatively rare gastric neoplasm. Before the routine use of laparoscopy, various methods of treatment for gastric leiomyoma included open celiotomy with gastric wedge resection, partial gastrectomy, enucleation, and extended gastrectomy with en bloc resection of adjacent organs. Below, we describ...
['Female', 'Gastrectomy', 'Humans', 'Laparoscopy', 'Leiomyoma', 'Middle Aged', 'Stomach Neoplasms', 'Treatment Outcome']
14,974,670
[['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C04.557.450.590.450'], ['M01.060.116.630'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Endometrial aspiration studies on Isaacs cell sampler with cytohistologic correlation.
Endometrial aspiration material obtained with the Isaacs cell sampler from 220 patients was studied and correlated with tissue biopsy from 172 of these patients. Of 52 endometrial carcinomas, there were two false-negative readings. In addition, five cases thought to be malignancies by cytologic criteria were not confir...
['Adenocarcinoma', 'Adult', 'Aged', 'Biopsy, Needle', 'Cytodiagnosis', 'Diagnosis, Differential', 'Endometrial Hyperplasia', 'Female', 'Humans', 'Middle Aged', 'Uterine Neoplasms']
294,773
[]
[]
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Unique case of gyrate atrophy with a well-preserved electroretinogram (ERG).
Gyrate atrophy is a rare autosomal recessive disorder caused by a mutation in the ornithine-ä-amino transferase gene. We present an interesting case of a 33-year-old woman who presented with increasing myopia, nyctalopia and failing vision. Examination revealed posterior subscapsular cataracts, narrowed peripheral visu...
['Adult', 'Cataract', 'Cataract Extraction', 'Diet, Protein-Restricted', 'Disease Progression', 'Electroretinography', 'Female', 'Gyrate Atrophy', 'Humans', 'Lens Implantation, Intraocular', 'Ornithine', 'Pyridoxine', 'Retinal Degeneration', 'Treatment Outcome', 'Visual Fields', 'Vitamins']
29,437,727
[['M01.060.116'], ['C11.510.245'], ['E04.540.825.249'], ['E02.642.249.280', 'G07.203.650.240.280'], ['C23.550.291.656'], ['E01.370.380.225', 'E01.370.405.270'], ['C11.270.468', 'C11.941.160.578', 'C16.320.290.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['D12.125.068.665', 'D12.125.095.7...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]']
0
1
1
1
1
1
1
0
0
1
0
1
1
0
Clinical economics and sleep disorders.
Sleep disorders have been shown to have substantial psychosocial sequelae with large economic impact. Numerous studies have examined the psychosocial aspects of sleep disorders; however, there has been little published on the associated economic implications. With increasing pressure to contain health care expenditures...
['Costs and Cost Analysis', 'Health Care Costs', 'Humans', 'Quality of Life', 'Sleep Wake Disorders']
9,415,941
[['N03.219.151'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['C10.886', 'C23.888.592.796', 'F03.870']]
['Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Psychiatry and Psychology [F]']
0
1
1
0
0
1
0
0
1
0
0
0
1
0
Spectral analysis highlight developmental EEG changes in preterm infants without overt brain damage.
Early markers of neurological outcome in the absence of overt brain damage are scarce in extreme prematurity. The aim of this study was to compare spectral EEG values of infants born near term with those of infants born at extremely low gestational age (ELGA) but having attained near term age. We aimed also to evaluate...
['Brain', 'Brain Waves', 'Electroencephalography', 'Female', 'Gestational Age', 'Humans', 'Infant, Extremely Premature', 'Infant, Newborn', 'Male', 'Signal Processing, Computer-Assisted']
28,412,532
[['A08.186.211'], ['E01.370.376.300.150', 'E01.370.405.245.287', 'G07.265.087', 'G11.561.127'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.520.500'], ['M01.060.703.520'], ['L01.224.800']]
['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]']
1
1
0
0
1
0
1
0
0
0
1
1
0
0
Anti-arthritic potential of the plant Justicia gendarussa Burm F.
OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models.MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. Th...
['Acanthaceae', 'Adjuvants, Immunologic', 'Animals', 'Arthritis, Experimental', 'Cattle', 'Collagen Type II', 'Drug Evaluation, Preclinical', "Freund's Adjuvant", 'Phytotherapy', 'Plant Extracts', 'Rats', 'Rats, Wistar']
19,488,595
[['B01.650.940.800.575.912.250.583.040'], ['D27.505.696.477.067'], ['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280.300.200', 'D12.776.860.300.250.300.200'], ['E05.290.750', 'E05.337.550'], ['D20.475'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['B01...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
1
1
0
0
0
0
0
0
0
0
0
A geometrical model of speed skating the curves.
The centripetal force in speed skating the curves has to be delivered by the push off force which also does the external work to maintain the speed. Based on the geometry of the speed skating oval and the sideward push off characteristics in speed skating, a mathematical model of the power output in skating the curves ...
['Acceleration', 'Adult', 'Biomechanical Phenomena', 'Computer Simulation', 'Female', 'Humans', 'Mathematics', 'Microcomputers', 'Skating', 'Sports']
3,209,589
[['G01.482.107'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['L01.224.230.260.550'], ['I03.450.642.845.700'], ['I03.450.642.845']]
['Phenomena and Processes [G]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
0
1
0
0
0
0
1
1
1
0
1
1
0
0
Simultaneous enzymatic and SERS properties of bifunctional chitosan-modified popcorn-like Au-Ag nanoparticles for high sensitive detection of melamine in milk powder.
In this work, we suggest a chitosan-modified popcorn-like Au-Ag nanoparticles (CSPNPs) based assay for high sensitive detection of melamine, in which CSPNPs not only provide with an intrinsic peroxidase-like activity but also act as surface enhanced Raman scattering (SERS) substrates. CSPNPs can catalyze the oxidation ...
['Animals', 'Chitosan', 'Food Analysis', 'Gold', 'Limit of Detection', 'Metal Nanoparticles', 'Milk', 'Peroxidase', 'Silver', 'Spectrum Analysis, Raman', 'Triazines']
26,048,843
[['B01.050'], ['D05.750.078.139.500', 'D09.698.211.500'], ['E05.362', 'J01.576.423.850.100'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['J01.637.512.600.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350....
['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
1
0
0
1
0
Influence of patient age and sex on delivery of guideline-recommended heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF.
BACKGROUND: The influence of patient age and sex on delivery of guideline-recommended heart failure (HF) therapies in contemporary outpatient settings has not been well studied. The Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF) is a prospective cohort study...
['Age Factors', 'Aged', 'Cardiology', 'Delivery of Health Care', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Morbidity', 'Outpatients', 'Practice Guidelines as Topic', 'Prospective Studies', 'Registries', 'Sex Factors', 'Survival Rate', 'United States']
19,332,206
[['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['H02.403.429.163'], ['N04.590.374', 'N05.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525', 'N01.22...
['Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]']
0
1
1
0
1
0
0
1
0
0
0
1
1
1
Longitudinal in vivo MRI of alterations in perilesional tissue after transient ischemic stroke in rats.
Spontaneous restoration of function after stroke is associated with remodelling of functional neuronal networks in and around the ischemic lesion. However, the spatiotemporal profile of structural alterations in (peri)lesional tissue in relation to post-stroke recovery of neuronal function remains largely to be elucida...
['Animals', 'Brain', 'Brain Infarction', 'Brain Ischemia', 'Diffusion Magnetic Resonance Imaging', 'Disease Models, Animal', 'Disease Progression', 'Ischemic Attack, Transient', 'Magnetic Resonance Imaging', 'Male', 'Nerve Fibers, Myelinated', 'Neural Pathways', 'Rats', 'Rats, Wistar', 'Reperfusion Injury', 'Time', 'Ti...
18,501,349
[['B01.050'], ['A08.186.211'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E01.370.350.825.500.150'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.656'], ...
['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
1
0
1
0
1
0
0
0
0
0
0
0
Prevalence of methicillin-resistant Staphylococcus aureus in skin and soft tissue infections in patients presenting to Canadian emergency departments.
BACKGROUND: Community-associated methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common cause of skin and soft tissue infection (SSTI) worldwide. The prevalence of MRSA in SSTIs across Canada has not been well described. Studies in the United States have shown significant geographic variability in...
['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Canada', 'Child', 'Child, Preschool', 'Electrophoresis, Gel, Pulsed-Field', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Middle Aged', 'Prevalence', 'Prospective Studies', 'So...
23,663,462
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.176'], ['M01.060.406'], ['M01.060.406.448'], ['E05.196.401.220', 'E05.301.300.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750....
['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]']
0
1
1
0
1
0
0
0
0
0
0
1
1
1
Genetic links, family ties, and social bonds: rights and responsibilities in the face of genetic knowledge.
Currently, some of the most significant moral issues involving genetic links relate to genetic knowledge. In this paper, instead of looking at the frequently addressed issues of responsibilities professionals or institutions have to individuals, I take up the question of what responsibilities individuals have to one an...
['Beneficence', 'Disclosure', 'Ethics, Medical', 'Family Relations', 'Female', 'Friends', 'Genetic Counseling', 'Genetic Diseases, Inborn', 'Genetic Privacy', 'Genetic Research', 'Genetics, Medical', 'Genetics, Population', 'Humans', 'Male', 'Moral Obligations', 'Patient Advocacy', 'Patient Participation', 'Personal Au...
9,555,632
[['K01.752.566.479.830.500', 'N05.350.958.500'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['F01.829.263.370', 'I01.880.853.150.439'], ['M01.252'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['C16.320'], ['I01.880.604.473.352.500.320'...
['Humanities [K]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]']
0
1
1
0
0
1
0
1
1
0
1
1
1
0
Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities.
New microtubule depolymerizing agents with potent cytotoxic activities have been prepared with a 5-cyano or 5-oximino group attached to a pyrrole core. The utilization of ortho activation of a bromopyrrole ester to facilitate successful Suzuki-Miyaura cross-coupling reactions was a key aspect of the synthetic methodolo...
['Animals', 'Antineoplastic Agents', 'Cattle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Halogenation', 'Humans', 'Microtubules', 'Molecular Docking Simulation', 'Neoplasms', 'Pyrroles', 'Rats']
28,433,513
[['B01.050'], ['D27.505.954.248'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G02.111.323', 'G03.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.750.602'], ['E05.599.595.249', 'L01.224.160.249'], [...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]']
1
1
1
1
1
0
1
0
0
0
1
0
0
0
A novel germ line p53 mutation in intron 6 in diverse childhood malignancies.
Screening for p53 mutations in exons 5 to 8 in 124 pediatric malignancies identified 18 abnormal shifts using single strand conformation polymorphism: 12 were missense mutations and in 6, no mutation was detected in the exon or in the splice donor acceptor sequences. Sequencing was then performed in the adjacent intron...
['Brain Neoplasms', 'Child', 'Exons', 'Female', 'Genes, p53', 'Germ-Line Mutation', 'Humans', 'Introns', 'Li-Fraumeni Syndrome', 'Lymph Nodes', 'Male', 'Point Mutation', 'Polymorphism, Single-Stranded Conformational', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'RNA Splicing', 'Rhabdomyosarcoma', 'Tumor Suppresso...
9,129,144
[['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['G05.365.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['C0...
['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
1
1
0
0
1
0
0
0
0
1
0
0
Simultaneous calcium fluorescence imaging and MR of ex vivo organotypic cortical cultures: a new test bed for functional MRI.
Recently, several new functional (f)MRI contrast mechanisms including diffusion, phase imaging, proton density, etc. have been proposed to measure neuronal activity more directly and accurately than blood-oxygen-level dependent (BOLD) fMRI. However, these approaches have proved difficult to reproduce, mainly because of...
['Animals', 'Biomimetics', 'Brain Mapping', 'Calcium', 'Calcium Signaling', 'Cells, Cultured', 'Cerebral Cortex', 'Equipment Design', 'Equipment Failure Analysis', 'Magnetic Resonance Imaging', 'Microscopy, Fluorescence', 'Multimodal Imaging', 'Nerve Net', 'Organ Culture Techniques', 'Rats', 'Rats, Sprague-Dawley', 'Re...
26,510,537
[['B01.050'], ['H01.158.550.100', 'J01.897.120.100'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['E05.320'], ['E05.325.192'...
['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]']
1
1
0
1
1
0
1
1
0
1
0
0
1
0
Surgical management of flash pulmonary edema secondary to renovascular hypertension.
BACKGROUND: Flask pulmonary edema (FPE) may be a manifestation of renovascular hypertension (RVHTN) and unresponsive to antihypertensive therapy.METHODS: Response to antihypertensive therapy and perioperative outcomes were determined in 5 consecutive patients with FPE.RESULTS: A mean of 2.3 admissions for the treatment...
['Aged', 'Analysis of Variance', 'Anastomosis, Surgical', 'Aorta, Abdominal', 'Blood Vessel Prosthesis', 'Humans', 'Hypertension, Renovascular', 'Iliac Artery', 'Middle Aged', 'Pulmonary Edema', 'Renal Artery', 'Retrospective Studies', 'Saphenous Vein', 'Treatment Outcome', 'Vascular Surgical Procedures']
9,293,835
[['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E04.035'], ['A07.015.114.056.205'], ['E07.695.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.331.490', 'C13.351.968.419.331.490', 'C14.907.489.631.485'], ['A07.015.114.444'], ['M01.060.116.630'], ['C08.381....
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting.
PURPOSE: To update the 1999 American Society of Clinical Oncology (ASCO) guideline on breast cancer follow-up and management in the adjuvant setting.METHODS: An ASCO Expert Panel reviewed pertinent information from the literature through March 2006. More weight was given to studies that tested a hypothesis directly rel...
['Breast Neoplasms', 'Chemotherapy, Adjuvant', 'Expert Testimony', 'Female', 'Genetic Counseling', 'Humans', 'Mammography', 'Mass Screening', 'Medical History Taking', 'Medical Oncology', 'Palpation', 'Physical Examination', 'Population Surveillance', 'Radiotherapy, Adjuvant', 'Referral and Consultation', 'Societies, M...
17,033,037
[['C04.588.180', 'C17.800.090.500'], ['E02.186.170', 'E02.319.170'], ['I01.880.604.583.232', 'N03.706.535.253'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.30...
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
1
0
1
0
1
1
1
0
0
0
1
0
Risk and prevention of graft failure in patients with preexisting donor-specific HLA antibodies undergoing unmanipulated haploidentical SCT.
A role of donor-specific HLA antibodies (DSA) in graft failure after SCT has been suggested, but the relevance of DSA in unmanipulated haploidentical SCT (haplo-SCT) remains unknown. We prospectively examined HLA antibodies using the Luminex-based single Ag assay for 79 adult patients undergoing unmanipulated haplo-SCT...
['Adolescent', 'Adult', 'Donor Selection', 'Female', 'Graft Rejection', 'HLA Antigens', 'Hematologic Neoplasms', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Isoantibodies', 'Male', 'Risk Factors', 'Tissue Donors', 'Transplantation, Homologous']
21,691,261
[['M01.060.057'], ['M01.060.116'], ['E04.936.537.500', 'N02.421.911.600'], ['G12.875.545.328'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['C04.588.448', 'C15.378.400'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.664', 'D12.776.12...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]']
0
1
1
1
1
0
1
0
0
0
0
1
1
0
Photoacoustic analysis of the ultrasonic irradiation effect in the photosynthetic activity in aquatic lirium plants.
We report, the application of the photoacoustic technique for monitoring the photosynthesis evolution in aquatic lirium (Eichhornia Crassipes), before and after it was exposed to ultrasonic irradiations. We obtained the disappearance of the phototobaric contribution in the PA signal measured for the irradiated samples ...
['Acoustics', 'Eichhornia', 'Photochemical Processes', 'Photosynthesis', 'Ultrasonics']
23,916,598
[['H01.671.031'], ['B01.650.940.800.575.912.250.827.500'], ['G02.740'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['H01.671.031.849']]
['Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
0
0
0
0
1
1
0
0
0
0
0
0
Effects of growth factors on acid-induced damage to rat gastric epithelial cells.
We previously established a model of cell damage induced by an acidified medium in the rat gastric epithelial cell line RGM1. Treatment of the cells with epidermal growth factor (EGF, 1-10 ng/ml) for 4 h prevented acid-induced cell damage in a concentration-dependent manner. In contrast, basic fibroblast growth factor ...
['Amiloride', 'Animals', 'Becaplermin', 'Cell Division', 'Cell Line', 'Culture Media', 'Cycloheximide', 'Epidermal Growth Factor', 'Fibroblast Growth Factor 2', 'Gastric Acid', 'Gastric Mucosa', 'Humans', 'Platelet-Derived Growth Factor', 'Proto-Oncogene Proteins c-sis', 'Rats', 'Recombinant Proteins', 'Sodium-Hydrogen...
9,479,630
[['D03.383.679.149'], ['B01.050'], ['D12.644.276.910.650.500', 'D12.776.260.690.500', 'D12.776.467.910.650.500', 'D23.529.910.650.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D27.720.470.305', 'E07.206'], ['D03.383.621.808.240'], ['D06.472.317.350', 'D12.644.276.38...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Multiple brain parenchymal neurocysticercosis with extraocular muscle cysticercosis affecting levator palpebral superioris and superior rectus complex: an unusual association.
An 8-year-old girl presented to the neurology department with a complaint of insidious onset of left-sided ptosis and restricted elevation of the left eye. A CT scan orbit and brain revealed a ring-enhancing lesion in the levator palpebral superioris (LPS) and superior rectus (SR) muscle complex of the left eye and lef...
['Albendazole', 'Anti-Inflammatory Agents', 'Anticestodal Agents', 'Blepharoptosis', 'Brain Diseases', 'Child', 'Cysticercosis', 'Dexamethasone', 'Female', 'Humans', 'Neurocysticercosis', 'Oculomotor Muscles', 'Radiography']
23,355,567
[['D02.241.081.251.022', 'D03.633.100.103.070'], ['D27.505.954.158'], ['D27.505.954.122.250.075.100.040'], ['C11.338.204'], ['C10.228.140'], ['M01.060.406'], ['C01.610.335.190.902.185'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.207.205.250.550', 'C01...
['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
1
1
0
0
0
0
0
0
1
0
0
An atypic pattern of the azygos venous system in man.
A rare variation of the azygos system, found in an 84 year old man, is described. A "double-columned" azygos system runs in front of the spine, and the azygos major crosses the superior lobe of the right lung and enters the right subclavian vein.
['Aged', 'Aged, 80 and over', 'Azygos Vein', 'Humans', 'Male']
3,400,891
[['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.908.106'], ['B01.050.150.900.649.313.988.400.112.400.400']]
['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
0
0
0
0
0
0
0
0
1
0
0
Fractionation and characterization of the phosphoenolpyruvate: fructose 1-phosphotransferase system from Pseudomonas aeruginosa.
The initial reactions involved in the catabolism of fructose in Pseudomonas aeruginosa include the participation of a phosphoenolpyruvate:fructose 1-phosphotransferase system (F-PTS). Fractionation of crude extracts of fructose-grown cells revealed that both membrane-associated and soluble components were essential for...
['Enzyme Induction', 'Escherichia coli', 'Hydrogen-Ion Concentration', 'Kinetics', 'Magnesium', 'Phosphoenolpyruvate Sugar Phosphotransferase System', 'Pseudomonas aeruginosa', 'Salmonella typhimurium', 'Species Specificity', 'Substrate Specificity']
6,799,490
[['G05.308.320.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D05.500.562.484', 'D08.811.600.700', 'D08.811.913.696.620.650'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['B03.440.4...
['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]']
0
1
0
1
0
0
1
0
0
0
0
0
0
0
Physical interaction with monocytes rescues human mature CD4+ T-cell lines from anti-CD3-induced apoptosis.
Crosslinking of the TcR-CD3 complex with immobilized anti-CD3 antibodies without sufficient co-stimulation induced cell death in human mature CD4+ T-cell lines. In these T cells, DNA fragmentation and morphological characteristics of apoptosis were seen. The anti-CD3-induced apoptosis was inhibited by co-culture with m...
['Antibodies, Monoclonal', 'Apoptosis', 'CD3 Complex', 'CD4-Positive T-Lymphocytes', 'Cell Communication', 'Cell Differentiation', 'Cell Line', 'DNA Replication', 'Humans', 'Immunosuppressive Agents', 'Monocytes']
7,590,934
[['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.146.954.035'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.085'], ['G04.152'], ['A11.251.210'], ['G02.111...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
[Manufacturing inspection in ensuring sanitary and epidemiological well-being of the population].
The paper shows the role and place of manufacturing control over the observance of the sanitary-and-epidemiological well-being of the population. Necessary conditions for the effective functioning of a manufacturing control system are formulated.
['Humans', 'Hygiene', 'Occupational Health', 'Quality of Life', 'Russia', 'Sanitation']
20,135,866
[['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547', 'N06.850.670'], ['N01.400.525'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['Z01.252.122.500', 'Z01.542.248.775'], ['H02.229.782', 'N06.850.780.200.800', 'N06.850.860']]
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]', 'Disciplines and Occupations [H]']
0
1
0
0
1
0
0
1
1
0
0
0
1
1
Tests of the sorption and olfactory "fovea" hypotheses in the mouse.
The spatial distribution of receptors within sensory epithelia (e.g., retina and skin) is often markedly nonuniform to gain efficiency in information capture and neural processing. By contrast, odors, unlike visual and tactile stimuli, have no obvious spatial dimension. What need then could there be for either nearest-...
['Air Movements', 'Analysis of Variance', 'Animals', 'Chemoreceptor Cells', 'Computer Simulation', 'Electrodiagnosis', 'Female', 'Hydrodynamics', 'Mice', 'Models, Neurological', 'Odorants', 'Olfactory Mucosa', 'Physical Stimulation', 'Respiration', 'Smell']
28,877,965
[['G16.500.175.249', 'G16.500.275.063.725.154', 'N06.230.300.100.150.185'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.675.650.915.500', 'A08.800.950.500', 'A11.671.650.915.500'], ['L01.224.160'], ['E01.370.405'], ['G01.342'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05...
['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Psychiatry and Psychology [F]']
1
1
0
0
1
1
1
0
0
0
1
0
1
0
Novel guanidinylated bioresponsive poly(amidoamine)s designed for short hairpin RNA delivery.
Two different disulfide (SS)-containing poly(amidoamine) (PAA) polymers were constructed using guanidino (Gua)-containing monomers (ie, arginine [Arg] and agmatine [Agm]) and N,N'-cystamine bisacrylamide (CBA) by Michael-addition polymerization. In order to characterize these two Gua-SS-PAA polymers and investigate the...
['Cell Survival', 'DNA', 'Fanconi Anemia Complementation Group E Protein', 'Humans', 'MCF-7 Cells', 'Microscopy, Atomic Force', 'Particle Size', 'Plasmids', 'Polyamines', 'Polyethyleneimine', 'Polymerization', 'Polymers', 'RNA, Small Interfering', 'Transfection']
27,994,462
[['G04.346'], ['D13.444.308'], ['D12.776.313.843', 'D12.776.660.289'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['G02.712'], ['G05.360.600'], ['D02.092.782'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D05.750.716.507.600', 'D25.720.7...
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]']
1
1
0
1
1
0
1
0
0
1
0
0
0
0
Optical control of protein activity and gene expression by photoactivation of caged cyclofen.
The use of light to control the expression of genes and the activity of proteins is a rapidly expanding field. While many of these approaches use a fusion between a light activatable protein and the protein of interest to control the activity of the latter, it is also possible to control the activity of a protein by un...
['Animals', 'Gene Expression', 'Light', 'Optogenetics', 'Photochemical Processes', 'Polycyclic Compounds', 'Receptors, Estrogen', 'Transcriptional Activation', 'Zebrafish', 'Zebrafish Proteins']
31,370,925
[['B01.050'], ['G05.297'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.393.667'], ['G02.740'], ['D04'], ['D12.776.826.750.350', 'D12.776.930.778.350'], ['G05.308.800'], ['B01.050.150.900.493.200.244.828'], ['D12.776.325.500']]
['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Risk factors for surgical site infections among 1,772 patients operated on for lumbar disc herniation: a multicentre observational registry-based study.
BACKGROUND: There are no previous studies evaluating risk factors for surgical site infections (SSIs) and the effectiveness of prophylactic antibiotic treatment (PAT), specifically for patients operated on for lumbar disc herniation.METHOD: This observational multicentre study comprises a cohort of 1,772 consecutive pa...
['Adult', 'Aged', 'Antibiotic Prophylaxis', 'Female', 'Humans', 'Intervertebral Disc Displacement', 'Laminectomy', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Registries', 'Risk Factors', 'Surgical Wound Infection']
28,424,918
[['M01.060.116'], ['M01.060.116.100'], ['E02.319.162.150', 'E02.319.703.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E05.318.308.970', 'N04.452.859.819', 'N05....
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
Cyclic voltammetry modeling, geometries, and electronic properties for metallofullerene complexes with mu3-eta2:eta2:eta2-C60 bonding mode.
Reduction potential (E(red)) values have been calculated and compared with available cyclic voltammetry (CV) data for 10 metallofullerene complexes with the mu(3)-eta(2):eta(2):eta(2)-C(60) (M(3)-C(6)[C(60)]) bonding mode. Consideration of bulk solvent effects is essential for the calculation of the E(red) values. Scal...
['Electrochemistry', 'Fullerenes', 'Iridium', 'Metals, Heavy', 'Models, Chemical', 'Molecular Conformation', 'Osmium', 'Oxidation-Reduction', 'Rhenium', 'Rhodium', 'Solubility', 'Static Electricity']
17,279,498
[['H01.181.529.307'], ['D01.268.150.250', 'J01.637.512.600.612.350'], ['D01.268.556.401', 'D01.268.956.280', 'D01.552.544.401'], ['D01.268.556', 'D01.552.544'], ['E05.599.495'], ['G02.111.570.820'], ['D01.268.556.660', 'D01.268.956.702', 'D01.552.544.660'], ['G02.700', 'G03.295.531'], ['D01.268.556.787', 'D01.268.956.7...
['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
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Prohibitin expression is increased in phorbol ester-treated chronic leukemic B-lymphocytes.
Chronic lymphocytic leukemia (CLL) is characterized by the gradual accumulation of immature B-lymphocytes. CLL B-lymphocytes mature to a plasmacytoid phenotype when treated in vitro with phorbol esters. CLL B-cell apparent maturation is associated with altered expression of specific plasma membrane and mitochondrial pr...
['Antineoplastic Agents', 'B-Lymphocytes', 'Blotting, Western', 'Cell Division', 'Cell Size', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Oligonucleotides, Antisense', 'Phorbol Esters', 'Protein Biosynthesis', 'Proteins', 'Repressor Proteins', 'Tetradecanoylphorbol Acetate', 'Up-Regulation']
11,162,143
[['D27.505.954.248'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['...
['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]']
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Stroke and renal artery stenosis from Takayasu's arteritis diagnosed in a 57-year-old male patient.
Takayasu arteritis (TA) is a rare chronic granulomatous inflammatory arterial disease of unknown etiology that affects the aorta, its main branches and pulmonary artery. The clinical presentation is nonspecific, with signs and symptoms that vary according to the affected arterial segment. The most commonly affected ves...
['Cardiovascular Agents', 'Glucocorticoids', 'Humans', 'Infarction, Middle Cerebral Artery', 'Male', 'Middle Aged', 'Renal Artery Obstruction', 'Takayasu Arteritis', 'Treatment Outcome']
31,249,238
[['D27.505.954.411'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.150.477.200.450', 'C10.228.140.300.510.200.387', 'C10.228.140.300.775.200.200.450', 'C14.907.253.092.477.200.450', 'C14.907.253.560.200.387', 'C14.907.253.855.200.200.450', 'C23.550.5...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
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Sociodemographic characteristics and beverage intake of children who drink tap water.
BACKGROUND: Tap water provides a calorie-free, no-cost, environmentally friendly beverage option, yet only some youth drink it.PURPOSE: To examine sociodemographic characteristics, weight status, and beverage intake of those aged 1-19 years who drink tap water.METHODS: National Health and Nutrition Examination Survey d...
['Adolescent', 'Age Factors', 'Beverages', 'Child', 'Child, Preschool', 'Drinking Behavior', 'Drinking Water', 'Educational Status', 'Ethnic Groups', 'Female', 'Humans', 'Infant', 'Male', 'Nutrition Surveys', 'Sex Factors', 'Socioeconomic Factors', 'United States', 'Young Adult']
23,790,991
[['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['G07.203.100', 'J02.200'], ['M01.060.406'], ['M01.060.406.448'], ['F01.145.317'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['N01.824.196'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900...
['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenome...
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Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila.
Model organisms such as the fruit fly Drosophila melanogaster can help to elucidate the molecular basis of complex diseases such as cancer. Mutations in the Drosophila gene lethal (3) malignant brain tumor cause malignant growth in the larval brain. Here we show that l(3)mbt tumors exhibited a soma-to-germline transfor...
['Animals', 'Argonaute Proteins', 'Brain', 'Brain Neoplasms', 'Cell Transformation, Neoplastic', 'DEAD-box RNA Helicases', 'DNA-Binding Proteins', 'Disease Models, Animal', 'Drosophila Proteins', 'Drosophila melanogaster', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Genes, Insect', 'Genes, T...
21,205,669
[['B01.050'], ['D08.811.277.352.355.350.810.500', 'D08.811.277.352.700.350.810.500', 'D12.776.157.725.500.906.500', 'D12.776.664.962.500.906.500'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D08.811.913.696.445.735.720.249'], ['D12.776.2...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
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Clinical response to chemotherapy and hormone therapy as first treatment after therapeutic ovariectomy in advanced breast cancer patients.
The results of chemotherapy and hormone therapy, administered after relapse of the disease, were evaluated in 106 patients with homogeneous clinical characteristics who were subjected to bilateral ovariectomy for advanced breast cancer, whether the response to castration was favorable or not. In spite of an unfavorable...
['Adult', 'Antineoplastic Agents', 'Breast Neoplasms', 'Castration', 'Cyclophosphamide', 'Dexamethasone', 'Doxorubicin', 'Female', 'Fluorouracil', 'Hormones', 'Humans', 'Methotrexate', 'Methyltestosterone', 'Middle Aged', 'Neoplasms, Hormone-Dependent', 'Progestins', 'Tamoxifen', 'Testosterone', 'Vincristine']
6,214,880
[['M01.060.116'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['E04.270.282', 'E04.950.165'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D03....
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
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