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Occlusion properties of prosthetic contact lenses for the treatment of amblyopia. | BACKGROUND: The efficacy of opaque contact lenses as occlusion therapy for amblyopia has been established in the literature. Prosthetic contact lenses use similar tints to improve cosmesis in scarred or deformed eyes and may be an alternative in occlusion therapy. To test this idea, we determined the degree of vision p... | ['Adult', 'Amblyopia', 'Analysis of Variance', 'Color', 'Contact Lenses, Hydrophilic', 'Cosmetic Techniques', 'Equipment Design', 'Humans', 'Iris', 'Pupil', 'Treatment Outcome', 'Visual Acuity'] | 18,595,755 | [['M01.060.116'], ['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.590.540.199'], ['E07.632.500.276.360'], ['E02.218'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.450', 'A09.371... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Outcomes of Endovascular Thrombectomy Performed 6-24 h after Acute Stroke from Extracranial Internal Carotid Artery Occlusion. | Thrombectomy has demonstrated clinical efficacy against acute ischemic stroke caused by intracranial occlusion of the internal carotid artery (ICA), even if performed 6-24 h after onset. This study investigated the outcomes of thrombectomy performed 6-24 h after stroke onset caused by extracranial ICA occlusion. Of 586... | ['Carotid Artery Thrombosis', 'Databases, Factual', 'Endovascular Procedures', 'Registries', 'Stroke', 'Thrombectomy', 'Time-to-Treatment', 'Treatment Outcome'] | 31,281,169 | [['C10.228.140.300.200.355', 'C14.907.253.123.355', 'C14.907.253.566.206', 'C14.907.355.590.213.206'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.100.814.529', 'E04.502.382'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['C10.228.140.300.775', 'C14.907.253.85... | ['Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Parameter importance in FRAP acquisition and analysis: a simulation approach. | Fluorescence recovery after photobleaching (FRAP) is a widespread technique used to determine intracellular reaction and diffusion parameters. In recent years, due to technical advances and an increasing number of mathematical models for analysis, there was a resurging interest in FRAP applications. However, care has t... | ['Computer Simulation', 'Fluorescence Recovery After Photobleaching', 'Monte Carlo Method'] | 23,663,852 | [['L01.224.160'], ['E05.196.712.516.600.393'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
High virulent clinical isolates of Mycobacterium abscessus from patients with the upper lobe fibrocavitary form of pulmonary disease. | Pulmonary disease caused by nontuberculous mycobacteria (NTM), including Mycobacterium abscessus, can be classified into two distinct types of clinical disease; the upper lobe fibrocavitary (UC) form and nodular bronchiectatic (NB) form. However, the relationship between mycobacterial strain virulence and disease type ... | ['Adult', 'Aged', 'Animals', 'Anti-Bacterial Agents', 'Cell Survival', 'Clarithromycin', 'Cytokines', 'Drug Resistance, Bacterial', 'Female', 'Humans', 'Lung', 'Lung Diseases', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Middle Aged', 'Mycobacterium', 'Mycobacterium Infections', 'Specific Pathogen-Free Organi... | 19,800,962 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['D27.505.954.122.085'], ['G04.346'], ['D02.540.576.500.992.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381'], ['A11.329.37... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tumor shedding and metastatic progression after tumor excision in patient-derived orthotopic xenograft models of triple-negative breast cancer. | Patient-derived orthotopic xenograft (PDOX) models have been verified as a useful method for studying human cancers in mice. Previous studies on the extent of metastases in these models have been limited by the necessity of welfare euthanasia (primary tumors reaching threshold size), at which point metastases may only ... | ['Animals', 'Cell Count', 'Disease Progression', 'Female', 'Humans', 'Liver Neoplasms', 'Lung Neoplasms', 'Mice', 'Neoplasm Micrometastasis', 'Neoplastic Cells, Circulating', 'Triple Negative Breast Neoplasms', 'Vimentin', 'Xenograft Model Antitumor Assays'] | 32,335,861 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.697.650.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal plasma flow and cardiac output during hydralazine and propranolol treatment in essential hypertension. | Eleven patients with essential hypertension were given hydralazine (25 mg b.i.d.) for 2 weeks, hydralazine and propranolol (80 mg b.i.d.) for the next 2 weeks, and propranolol alone for the last 2 weeks. The changes in the renal and systemic circulation elicited by the drugs were studied before start of medication and ... | ['Adult', 'Cardiac Output', 'Drug Evaluation', 'Drug Therapy, Combination', 'Humans', 'Hydralazine', 'Hypertension', 'Kidney', 'Male', 'Middle Aged', 'Propranolol', 'Regional Blood Flow'] | 653,302 | [['M01.060.116'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E05.290.625', 'E05.337.425'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.710.605.500'], ['C14.907.489'], ['A05.810.453'], ['M01.060.116.630'], ['D02.033.100.624.698.711', 'D02.033.755.624.698.711', 'D02.092.063.624.698.711'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Atypical clinical variants of hypothyrosis]. | Timely diagnosis of hypothyrosis was noted in 34% of patients only. Considerable difficulties in the diagnosis of disease were associated with an atypical course of disease in a number of patients. The authors discuss some problems of a clinical picture of hypothyrosis with arterial hypertension, sympatico-adrenal cris... | ['Adolescent', 'Adult', 'Aged', 'Diagnosis, Differential', 'Humans', 'Hypothyroidism', 'Middle Aged', 'Retrospective Studies'] | 1,780,290 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of high altitude on echocardiographically determined cardiac morphology and function in patients with coronary artery disease and healthy controls. | AIMS: To evaluate the impact of high altitude on cardiac morphology and function in patients with coronary artery disease (CAD) and healthy controls.METHODS AND RESULTS: Eight patients with a history of acute myocardial infarction [53 +/- 8 years, left ventricular (LV) ejection fraction 54 +/- 6%] and a low risk score ... | ['Acceleration', 'Adult', 'Altitude', 'Biomarkers', 'Case-Control Studies', 'Coronary Artery Disease', 'Echocardiography, Doppler, Color', 'Exercise Test', 'Female', 'Health Status Indicators', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Myocardium', 'Risk Assessment', 'Risk Factors', 'Stroke Volume', 'Ventri... | 20,139,441 | [['G01.482.107'], ['M01.060.116'], ['G16.500.275.058', 'N06.230.058'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.350.130.750.220.220', 'E01.370.350.850.220.220.220', 'E01.370.350.850.850.22... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of glycophospholipid anchors on proteins. | Many eukaryotic proteins are tethered to the plasma membrane by glycosyl phosphatidylinositol (GPI) membrane anchors. This unit provides a general approach for detecting GPI-anchored proteins. First, the detergent-partitioning behavior of a protein of interest is examined for characteristics of GPI-linked species. The ... | ['Animals', 'Antibodies', 'Biochemistry', 'Cell Membrane', 'Detergents', 'Glycosylphosphatidylinositols', 'Hydrolysis', 'Nitrous Acid', 'Octoxynol', 'Phosphatidylinositol Diacylglycerol-Lyase', 'Phospholipases', 'Polyethylene Glycols', 'Proteins', 'Radioisotopes'] | 18,429,111 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['H01.158.201', 'H01.181.122'], ['A11.284.149'], ['D27.720.877.265', 'J01.516.381'], ['D09.400.410.475', 'D10.390.475', 'D10.570.755.375.760.400.942.250'], ['G02.380'], ['D01.029.260.575', 'D01.625.600'], ['D02.033.455.250.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. | Topoisomerases class II (topoII) cleave and re-ligate the DNA double helix to allow the passage of an intact DNA strand through it. Chemotherapeutic drugs such as etoposide target topoII, interfere with the normal enzymatic cleavage/re-ligation reaction and create a DNA double-strand break (DSB) with the enzyme covalen... | ['Antineoplastic Agents, Phytogenic', 'Carrier Proteins', 'Cell Cycle Proteins', 'Cells, Cultured', 'DNA Breaks, Double-Stranded', 'DNA Repair', 'DNA-Binding Proteins', 'Endodeoxyribonucleases', 'Etoposide', 'G1 Phase', 'Humans', 'MRE11 Homologue Protein', 'Nuclear Proteins', 'Phosphorylation', 'Threonine'] | 21,087,997 | [['D27.505.954.248.179'], ['D12.776.157'], ['D12.776.167'], ['A11.251'], ['G05.200.210.220'], ['G02.111.222', 'G05.219'], ['D12.776.260'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.250', 'D09.408.348.275'], ['G04.144.500.320'], ['B01.050.150.900... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The decreased antibacterial activity of oral polymorphonuclear leukocytes coincides with the occurrence of virus-carrying oral lymphocytes and epithelial cells. | Patients suffering from periodontitis or periodontosis were selected for the study. Further subdivision of these groups was based on the presence or absence of herpes and/or adenoviruses in their oral lymphocytes and epithelial cells. The phagocytic and bactericidal activities of oral leukocytes isolated from the same ... | ['Adenoviruses, Human', 'Adolescent', 'Adult', 'Aggressive Periodontitis', 'Chemotaxis, Leukocyte', 'Child', 'Epithelium', 'Humans', 'Kinetics', 'Lymphocytes', 'Middle Aged', 'Mouth Mucosa', 'Neutrophils', 'Periodontal Diseases', 'Periodontitis', 'Reference Values', 'Simplexvirus'] | 2,826,320 | [['B04.280.030.500.350'], ['M01.060.057'], ['M01.060.116'], ['C07.465.714.533.161'], ['G04.198.424.233'], ['M01.060.406'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['M01.060.116.630'], ['A10.6... | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Usefulness of arterial spin-labeling images in periictal state diagnosis of epilepsy. | PURPOSE: Arterial spin-labeling (ASL) perfusion MRI, a noninvasive method of assessing cerebral blood flow, is becoming a diagnostic tool of epilepsy. This study was undertaken to evaluate the diagnostic validity of ASL in patients with status epilepticus (SE) in a periictal state.METHOD: Twenty cases with SE were stud... | ['Adult', 'Aged', 'Aged, 80 and over', 'Electroencephalography', 'Epilepsy', 'Female', 'Functional Laterality', 'Humans', 'Imaging, Three-Dimensional', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged', 'Spin Labels'] | 26,478,131 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Immunosuppressive therapy in polymyositis. | Immunosuppressive drugs were given to seven patients with polymyositis. The in-vitro activity of peripheral blood lymphocytes had previously been studied in five of these patients with findings suggestive of disturbed immunological processes. Some improvement occurred in five cases, but only in two was the improvement ... | ['Adolescent', 'Adrenal Cortex Hormones', 'Adult', 'Arthritis, Rheumatoid', 'Dermatomyositis', 'Female', 'Humans', 'Immunosuppression', 'Immunosuppressive Agents', 'Lymphocytes', 'Male', 'Middle Aged', 'Myositis', 'Prognosis', 'Scleroderma, Systemic'] | 5,096,559 | [['M01.060.057'], ['D06.472.040'], ['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ['D27.505.696.477.656'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of nafronyl on lactate and pyruvate in the cerebrospinal fluid of patients with senile dementia. | In a single-blind study, 12 men (mean age 63 years) with senile dementia were given nafronyl in a dosage of 100 mg eight times daily for a week, followed by 100 mg four times daily for 12 weeks. Rigorous clinical, laboratory and psychometric assessments revealed no toxicity and no significant effects on vital functions... | ['3,4-Dihydroxyphenylacetic Acid', 'Aged', 'Dementia', 'Furans', 'Glucose', 'Homovanillic Acid', 'Humans', 'Hydroxyindoleacetic Acid', 'Lactates', 'Male', 'Methoxyhydroxyphenylglycol', 'Middle Aged', 'Nafronyl', 'Pyruvates'] | 6,173,407 | [['D02.241.223.601.220'], ['M01.060.116.100'], ['C10.228.140.380', 'F03.615.400'], ['D03.383.312'], ['D09.947.875.359.448'], ['D02.241.223.601.521'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['D02.241.511.459'], ['D02.033.455.250.610'], ['M01.060.116.630'], ['D03.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Report of the Cent Gardes HIV Vaccines Conference. Part 1: The antibody response; Fondation M?rieux Conference Center, Veyrier-du-Lac, France, 25-27 October 2015. | The 2015 Cent Gardes Conference on HIV vaccines took place on October 25-27 at the Merieux Foundation Conference Center in Veyrier du Lac, near Annecy, France. The meeting reviewed progress in the development of HIV vaccines and identified new directions of future research. The field has advanced incrementally over the... | ['AIDS Vaccines', 'Animals', 'Antibodies, Neutralizing', 'Antibody Formation', 'Congresses as Topic', 'France', 'HIV Antibodies', 'HIV Infections', 'Humans', 'Immunity, Humoral', 'Immunization, Passive'] | 27,216,761 | [['D20.215.894.899.050'], ['B01.050'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['G12.450.050.370.250'], ['N03.540.199'], ['Z01.542.286'], ['D12.776.124.486.485.114.254.150.440', 'D12.776.124.790.651.114.254.150.440', 'D12.776.377.715.548.114.254.150.440'], ['C01.22... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Changes in clinical characteristics, course, and prognosis of inflammatory bowel disease during the last 5 decades: a population-based study from Copenhagen, Denmark. | BACKGROUND: It remains uncertain whether the increasing incidence of inflammatory bowel disease (IBD) during the last decades has been accompanied by an alteration in the presentation, course, and prognosis of the disease. To answer this question, 3 consecutive population-based IBD cohorts from Copenhagen, Denmark (196... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Inflammatory Agents', 'Cause of Death', 'Child', 'Cohort Studies', 'Colitis, Ulcerative', 'Colorectal Neoplasms', 'Crohn Disease', 'Denmark', 'Disease Progression', 'Female', 'Humans', 'Immunologic Factors', 'Incidence', 'Male', 'Middle Aged', 'Prevalence', 'Pr... | 17,206,705 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.158'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C06.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Muscle glutamine production in diabetic ketoacidotic rats. | The mechanism of activation of glutamine production by the hindlimb during diabetic ketoacidosis (DKA) was investigated in rats. Muscle glutamine production was estimated to account for over 90% of the total glutamine produced by the hindlimb. DKA produced significant increases in the concentrations of NH4+ and IMP in ... | ['Adipose Tissue', 'Alanine', 'Amino Acids', 'Aminoisobutyric Acids', 'Animals', 'Body Water', 'Diabetic Ketoacidosis', 'Glutamine', 'Hindlimb', 'In Vitro Techniques', 'Leucine', 'Male', 'Muscles', 'Rats', 'Rats, Inbred Strains', 'Skin', 'Starvation'] | 6,414,461 | [['A10.165.114'], ['D12.125.042'], ['D12.125'], ['D02.241.081.114.968.249', 'D12.125.070.075', 'D12.125.190.055'], ['B01.050'], ['A12.207.200'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ['A13.473'], ['E05.481'], ['D12.125.070.637',... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An evaluation of the impact of maternity care coordination on Medicaid birth outcomes in North Carolina. | BACKGROUND: Care coordination is an important component of the enhanced prenatal care services provided under the recent expansions of the Medicaid program. The effect of maternity care coordination services on birth outcomes in North Carolina was assessed by comparing women on Medicaid who did and did not receive thes... | ['Continuity of Patient Care', 'Cost Savings', 'Female', 'Health Care Costs', 'Humans', 'Infant Mortality', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Logistic Models', 'Maternal Health Services', 'Medicaid', 'Medical Record Linkage', 'North Carolina', 'Poverty', 'Pregnancy', 'Pregnancy Outcome', 'Program Evaluati... | 1,746,659 | [['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['N03.219.151.160.200'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520.460'], ['M01.060.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Axonal defects in mouse models of motoneuron disease. | Human motoneuron disease is characterized by loss of motor endplates, axonal degeneration, and cell death of motoneurons. The identification of the underlying gene defects for familial ALS, spinal muscular atrophy (SMA), and spinal muscular atrophy with respiratory distress (SMARD) has pointed to distinct pathophysiolo... | ['Aged', 'Alternative Splicing', 'Amyotrophic Lateral Sclerosis', 'Animals', 'Axonal Transport', 'Axons', 'Carrier Proteins', 'Caspase 2', 'Caspases', 'Cell Survival', 'Cells, Cultured', 'Ciliary Neurotrophic Factor', 'Cyclic AMP Response Element-Binding Protein', 'DNA-Binding Proteins', 'Disease Models, Animal', 'Embr... | 14,704,958 | [['M01.060.116.100'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells. | The placenta is a multifunctional organ that protects the fetus from toxic compounds and the MRPs contribute to this function. The expression of MRP1, MRP2, MRP3, and MRP5 was compared in human placental tissue and in BeWo cells by real-time RT-PCR analysis; protein expression was assessed by Western blot. MRP1 and MRP... | ['Blotting, Western', 'Cell Line', 'Humans', 'Membrane Transport Proteins', 'Multidrug Resistance-Associated Proteins', 'Placenta', 'Protein Biosynthesis', 'RNA', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Time Factors', 'Transcription, Genetic', 'Tumor Cells, Cultur... | 12,646,196 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530', 'D12.776.543.585'], ['D12.776.157.530.100.304', 'D12.776.157.530.450.074.500.500.500', 'D12.776.543.585.100.304', 'D12.776.543.585.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of school-level variables on aggression and associated attitudes of middle school students. | This study sought to understand school-level influences on aggressive behavior and related social cognitive variables. Participants were 5106 middle school students participating in a violence prevention project. Predictors were school-level norms opposing aggression and favoring nonviolence, interpersonal climate (pos... | ['Adaptation, Psychological', 'Adolescent', 'Aggression', 'Attitude', 'Family', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Schools', 'Self Efficacy', 'Sex Factors', 'Social Behavior', 'Students', 'Violence'] | 21,930,006 | [['F01.058'], ['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.100'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['I02.783', 'J03.832'], ['F01.752.747.792.700'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.813'], ['M01.848'], ['I01.198.240.8... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Promoting a positive attitude in pediatric patients undergoing limb lengthening. | Pediatric patients undergoing external fixation for limb lengthening have to adjust to having the devices on their extremities for many months. This treatment requires a great deal of time and commitment from both the child and family in managing the device. Our hospital interdisciplinary limb lengthening (LLD) team di... | ['Adaptation, Psychological', 'Attitude to Health', 'Bone Lengthening', 'Child', 'Humans', 'Patient Care Planning', 'Patient Care Team', 'Patient Education as Topic'] | 8,164,987 | [['F01.058'], ['F01.100.150', 'N05.300.150'], ['E04.555.120'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.624'], ['N04.590.715'], ['I02.233.332.500', 'N02.421.726.407.680']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Early Diastolic Dysfunction after Cancer Chemotherapy: Primary Endpoint Results of a Multicenter Cardio-Oncology Study. | Asymptomatic diastolic dysfunction (DD) with preserved left ventricular ejection fraction (LVEF) is suspected to precede late cardiac events in cancer survivors treated by chemotherapy. We conducted the first multicenter study of early DD induced by chemotherapy. Patients who were candidates for standard dose chemother... | ['Adult', 'Antineoplastic Agents', 'Biomarkers', 'Case-Control Studies', 'Echocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Neoplasms', 'Peptide Fragments', 'Troponin I', 'Ventricular Dysfunction, Left'] | 29,428,939 | [['M01.060.116'], ['D27.505.954.248'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D06.472.699.584.625', 'D12.644.548.585.625', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
T4 plus T3 treatment in children with hypothyroidism and inappropriately elevated thyroid-stimulating hormone despite euthyroidism on T4 treatment. | AIMS: To evaluate the effect of addition of T3 to L-T4 treatment in children with congenital hypothyroidism (CH) who have inappropriately elevated thyroid-stimulating hormone (TSH) levels despite high normal serum T4 levels on L-T4 treatment.METHODS: Ten children (age 7.1 +/- 2 years) with CH whose TSH levels were pers... | ['Child', 'Child, Preschool', 'Congenital Hypothyroidism', 'Female', 'Humans', 'Hyperthyroxinemia', 'Male', 'Pituitary Gland', 'Thyroid Gland', 'Thyrotropin', 'Thyroxine', 'Treatment Outcome', 'Triiodothyronine'] | 20,190,547 | [['M01.060.406'], ['M01.060.406.448'], ['C05.116.099.343.347', 'C05.116.132.256', 'C16.320.240.625', 'C19.297.155', 'C19.874.482.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.410'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.357.352.435.500', 'A08.713.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors that influence the provision of sexual health care by Dutch cancer nurses. | A descriptive-correlational design was used with a sample of Dutch cancer nurses (n = 104) to describe provision of sexual health care (SHC) and to explore influential factors. This report is limited to the second goal. The Theory of Reasoned Action provided the conceptual framework for investigation of five previously... | ['Adult', 'Curriculum', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Services Needs and Demand', 'Humans', 'Job Description', 'Male', 'Middle Aged', 'Models, Nursing', 'Nursing Evaluation Research', 'Nursing Staff', 'Oncology Nursing', 'Regression Analysis', 'Sex', 'Surveys and Questionnaires'] | 7,665,318 | [['M01.060.116'], ['I02.158'], ['F01.100.150.500', 'N05.300.150.410'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.677.410'], ['M01.060.116.630'], ['E05.599.645'], ['H01.770.644.145.390.432', 'H02.478.395.432', 'N04.590.233.508.613.432'], ['M01.526.485.680', 'N02.360.6... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Prevalence and typology of potential drug interactions occurring in primary care patients. | PURPOSE: To investigate the prevalence and types of potential drug interactions in primary care patients to detect risky prescriptions as an essential condition to design intervention policies leading to an improvement in patient safety.METHODS: Cross-sectional descriptive study.SETTING: Two areas in Spain comprising 7... | ['Age Factors', 'Aged', 'Chronic Disease', 'Cross-Sectional Studies', 'Drug Interactions', 'Drug-Related Side Effects and Adverse Reactions', 'Female', 'Humans', 'Male', 'Medication Errors', 'Middle Aged', 'Pharmaceutical Preparations', 'Polypharmacy', "Practice Patterns, Physicians'", 'Prevalence', 'Primary Health Car... | 20,504,263 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.690.773.968'], ['C25.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.529', 'N02.421.450.500'], ['M01.060.116.630'], ['D26'], ['E02.319... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of internal irradiation on the maturing Purkinje cells in the rat. A Golgi study. | Continuous irradiation in utero is reported to produce mental retardation and gross abnormalities of the brain in the human. A few experimental studies conducted so far also report gross brain defects in animals exposed to continuous irradiation in utero. Despite the increasing use of nuclear energy for power and radio... | ['Age Factors', 'Animals', 'Body Weight', 'Brain', 'Injections, Intraperitoneal', 'Iodine Radioisotopes', 'Organ Size', 'Phosphorus Radioisotopes', 'Purkinje Cells', 'Radiation Dosage', 'Rats', 'Rats, Inbred Strains', 'Staining and Labeling'] | 2,437,253 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['E02.319.267.530.490'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E01.370.600.115.100.660', 'E05.041.124... | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Molecular Mapping and Candidate Gene Analysis for GA3 | Plants with shorter internodes are suitable for high-density planting, lodging resistance and the preservation of land resources by improving yield per unit area. In this study, we identified a locus controlling the short internode trait in watermelon using Zhengzhouzigua (long internode) and Duan125 (short internode) ... | ['Animals', 'Chromosome Mapping', 'Citrullus', 'Genetic Association Studies', 'Genetic Linkage', 'Mixed Function Oxygenases', 'Nematoda', 'Plant Diseases', 'Plant Proteins'] | 31,906,246 | [['B01.050'], ['E05.393.183'], ['B01.650.940.800.575.912.250.300.140'], ['E05.393.385'], ['G05.348'], ['D08.811.682.690.708'], ['B01.050.500.500.294'], ['G15.610'], ['D12.776.765']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ser77]transforming growth factor-beta 1. Selective biological activity and receptor binding in mink lung epithelial cells. | Transforming growth factor-beta 1 (TGF-beta 1) is a homodimeric protein stabilized by a single disulfide bridge between Cys77 on the respective monomers and two paired complementary hydrophobic interfaces between the two subunits. A TGF-beta 1 mutant with Cys77 replaced by serine has been expressed in stably transfecte... | ['Animals', 'Biological Assay', 'CHO Cells', 'Cell Line', 'Cricetinae', 'Cysteine', 'Disulfides', 'In Vitro Techniques', 'Mice', 'Mink', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Protein Conformation', 'Receptors, Transforming Growth Factor beta', 'Recombinant Proteins', 'Serine', 'Structure-Activity Relation... | 7,961,688 | [['B01.050'], ['E05.091'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E05.481'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cervical specimen order and performance measures of Chlamydia trachomatis diagnostic testing. | The orders of three endocervical specimens of 3,561 women for Chlamydia trachomatis testing were randomized to determine whether test performance measures of two nucleic acid amplification tests and a DNA probe were affected by swab order. Specimen collection order did not appear to affect the diagnostic accuracy of th... | ['Cervix Uteri', 'Chlamydia Infections', 'Chlamydia trachomatis', 'DNA Probes', 'Female', 'Humans', 'Ligase Chain Reaction', 'Nucleic Acid Amplification Techniques', 'Polymerase Chain Reaction', 'Specimen Handling', 'Uterine Cervical Diseases'] | 16,208,001 | [['A05.360.319.679.256'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.190.750'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy? | BACKGROUND AND OBJECTIVES: Levels of parathyroid hormone (PTH) and the phosphaturic hormone FGF23, a fibroblast growth factor (FGF) family member, increase early in chronic kidney disease (CKD) before the occurrence of hyperphosphatemia. This short-term 6-wk dose titration study evaluated the effect of two phosphate bi... | ['Acetates', 'Adult', 'Biomarkers', 'Bone Diseases, Metabolic', 'Calcium Compounds', 'Chelating Agents', 'Chronic Disease', 'Female', 'Fibroblast Growth Factors', 'Humans', 'Hyperparathyroidism, Secondary', 'Kidney Diseases', 'Male', 'Middle Aged', 'Parathyroid Hormone', 'Phosphates', 'Pilot Projects', 'Polyamines', 'S... | 19,965,540 | [['D02.241.081.018', 'D10.251.400.045'], ['M01.060.116'], ['D23.101'], ['C05.116.198', 'C18.452.104'], ['D01.146'], ['D27.505.519.914.500', 'D27.720.832.500'], ['C23.550.291.500'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355.480'], ['C12.777.419'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Visualization of myocardial perfusion after percutaneous myocardial septal ablation for hypertrophic cardiomyopathy using superharmonic imaging. | Harmonic imaging is used for detection of ultrasound contrast agents in myocardial perfusion studies. However, harmonic imaging has limitations because of the presence of tissue harmonics, which results in less specificity and sensitivity, thus, lower contrast-to-tissue ratio. We describe a clinical example using super... | ['Cardiomyopathy, Hypertrophic', 'Catheter Ablation', 'Contrast Media', 'Coronary Angiography', 'Coronary Circulation', 'Echocardiography', 'Ethanol', 'Female', 'Humans', 'Middle Aged', 'Phospholipids', 'Sulfur Hexafluoride'] | 12,712,021 | [['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E02.808.750.500', 'E04.014.760.500'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['G09.330.100.324'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], [... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
T-1, a mitotic arrester, alters centrosome configurations in fertilized sea urchin eggs. | T-1 induces modifications in the shape of the centrosome at division in fertilized eggs of the North American sea urchin, Lytechinus pictus. Phase contrast microscopy observations of mitotic apparatus isolated from T-1-treated (1.7-8.5 microM) eggs at first division shows that the centrosomes already begin to spread or... | ['Animals', 'Antibodies, Monoclonal', 'Centromere', 'Chromosomes', 'Fertilization', 'Fluorescent Antibody Technique', 'Microscopy, Fluorescence', 'Mitosis', 'Ovum', 'Resorcinols', 'Sea Urchins', 'Spindle Apparatus'] | 2,198,112 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['G08.686.784.277'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibiotic resistance in diarrheagenic Escherichia coli and Shigella strains isolated from children in Hanoi, Vietnam. | The MICs for 162 diarrheagenic Escherichia coli strains and 28 Shigella strains were determined on the basis of NCCLS guidelines. More than 75% of the strains were resistant to ampicillin, chloramphenicol (53.6% of Shigella strains), and trimethoprim-sulfamethoxazole. Multiresistance was detected in 89.5% of E. coli st... | ['Ampicillin Resistance', 'Anti-Bacterial Agents', 'Child', 'Chloramphenicol Resistance', 'Diarrhea', 'Drug Resistance', 'Drug Resistance, Bacterial', 'Dysentery, Bacillary', 'Escherichia coli', 'Escherichia coli Infections', 'Humans', 'Microbial Sensitivity Tests', 'Shigella', 'Trimethoprim Resistance', 'Trimethoprim,... | 15,673,777 | [['G06.099.225.500.600.050', 'G06.225.347.500.600.050', 'G07.690.773.984.269.347.500.600.050'], ['D27.505.954.122.085'], ['M01.060.406'], ['G06.099.225.750', 'G06.225.347.750', 'G07.690.773.984.269.347.750'], ['C23.888.821.214'], ['G07.690.773.984'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['C01.150.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Leukotriene B4 induces in vitro fibroblast chemotaxis. | In vitro fibroblast chemotaxis was studied in the presence of synthetic leukotriene B4 (LTB4) and of supernatants from ionophore-stimulated lymphocytes, monocytes, and basophils (LMB-S). LTB4 and LMB-S induced a dose-related, directed migration of human and rat embryonic fibroblasts. By checkerboard analysis, this resp... | ['Animals', 'Basophils', 'Cell Line', 'Cell Transformation, Neoplastic', 'Chemotaxis', 'Embryo, Mammalian', 'Fibroblasts', 'Humans', 'Leukotriene B4', 'Lymphocytes', 'Monocytes', 'Sarcoma', 'Synovial Fluid'] | 6,317,764 | [['B01.050'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['A16.254'], ['A11.329.228'], ['B0... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Labor law update--Part 2. | As a nurse moves away from the patient's bedside, the liability exposure for malpractice decreases. However, the nurse who moves into a management position faces another kind of liability-one regarding disciplinary actions such as employee terminations. | ['Disabled Persons', 'Employee Discipline', 'Humans', 'Liability, Legal', 'Nurse Administrators', 'Nursing Staff', 'Nursing, Supervisory', 'United States'] | 9,287,737 | [['M01.150'], ['N04.452.677.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583.490', 'N03.706.535.547'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['M01.526.485.680', 'N02.360.680'], ['N04.452.758.377.750'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Joint Committee on Aviation Pathology: XIV. Ischaemic heart disease: a problem in aircraft accident reconstruction. | A twin-engine light aircraft crashed at night on the third ILS approach. Runway Visual Range was 300 m. All four occupants were killed. The owner, aged 61, one of the two crew members, occupied the left-hand seat and was found to have an old, extensive antero-lateral infarct and severe coronary artery disease. There wa... | ['Accidents, Aviation', 'Aerospace Medicine', 'Forensic Medicine', 'Humans', 'Licensure', 'Male', 'Middle Aged', 'Myocardial Infarction'] | 921,659 | [['N06.850.135.185'], ['H02.403.029'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.110.510', 'N05.700.200.450'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Tapered optical fiber sensor using near-infrared fluorophores to assay hybridization. | We present an all-fiber hybridization assay sensor that relies on the evanescent field excitation of fluorescence from surface-bound fluorophores. The evanescent field is made accessible through the use of a long, adiabatically tapered single-mode fiber probe. A laser diode with a 785-nm wavelength is used in a pulsed ... | ['Binding Sites', 'Biosensing Techniques', 'Fiber Optic Technology', 'Fluorescent Dyes', 'Helicobacter pylori', 'In Situ Hybridization, Fluorescence', 'Infrared Rays', 'Lasers', 'Oligonucleotides', 'Optical Fibers', 'Organic Chemicals', 'RNA, Bacterial', 'RNA, Ribosomal', 'Surface Properties'] | 9,608,842 | [['G02.111.570.120'], ['E05.601.043'], ['H01.671.617.249'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
What are the determinants of gene expression levels and breadths in the human genome? | In complex organisms, different tissues express different genes, which ultimately shape the function and phenotype of each tissue. An important goal of modern biology is to understand how some genes are turned on and off in specific tissues and how the numbers of different gene expression products are determined. These... | ['Animals', 'DNA Methylation', 'Exons', 'Gene Expression Regulation', 'Genome, Human', 'Humans', 'Introns', 'Mice', 'Models, Genetic', 'Organ Specificity', 'Promoter Regions, Genetic'] | 21,945,885 | [['B01.050'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.360.340.024.340.137.232'], ['G05.308'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition by adrenergic neurone blocking agents of the relaxation induced by BRL 38227 in vascular, intestinal and uterine smooth muscle. | 1. The adrenergic neurone blocking agents, guanethidine and bretylium, have been tested for inhibitory activity against the actions of some relaxant drugs (BRL 38227, noradrenaline, sodium nitroprusside, theophylline) in vascular, intestinal and uterine smooth muscle. 2. In guinea-pig isolated taenia caeci pre-contract... | ['Animals', 'Aorta, Thoracic', 'Benzopyrans', 'Bretylium Compounds', 'Cromakalim', 'Female', 'Guanethidine', 'Guinea Pigs', 'Intestines', 'Male', 'Muscle Relaxation', 'Muscle, Smooth', 'Muscle, Smooth, Vascular', 'Nitroprusside', 'Norepinephrine', 'Potassium Chloride', 'Pyrroles', 'Rats', 'Rats, Sprague-Dawley', 'Sympa... | 1,422,581 | [['B01.050'], ['A07.015.114.056.372'], ['D03.383.663.283', 'D03.633.100.150'], ['D02.092.877.096.333'], ['D03.383.129.578.150', 'D03.383.663.283.455', 'D03.633.100.150.455'], ['D02.078.370.460'], ['B01.050.150.900.649.313.992.550'], ['A03.556.124'], ['G11.427.494.554'], ['A02.633.570', 'A10.690.467'], ['A02.633.570.491... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The localization of the lesion in patients with acute ophthalmoplegia, ataxia and areflexia (Miller Fisher syndrome). A serial multimodal neurophysiological study. | Results of comprehensive serial neurophysiological tests from onset to full recovery in 3 patients with the Miller Fisher syndrome (acute ophthalmoplegia, ataxia and areflexia) are presented. These included EMG and nerve conduction, late response (H and F wave) and direct facial motor and blink reflex studies, computer... | ['Acute Disease', 'Adolescent', 'Adult', 'Ataxia', 'Humans', 'Male', 'Middle Aged', 'Nervous System', 'Neurologic Examination', 'Ophthalmoplegia', 'Peripheral Nervous System Diseases', 'Reflex, Abnormal', 'Reflex, Pupillary', 'Syndrome'] | 2,835,120 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['C10.597.350.090', 'C23.888.592.350.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08'], ['E01.370.376.550', 'E01.370.600.550'], ['C10.292.562.750', 'C10.597.622.447', 'C11.590.472', 'C23.888.592.636.447'], ['C10.668.829'], ['C10.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Recurrent thrombotic thrombocytopenic purpura after viral infection. Clinical and histologic simulation of chronic glomerulonephritis. | We describe a patient with recurrent thrombotic thrombocytopenic purpura (TTP) manifested solely by aphasia after influenza infection. The clinical diagnosis was not made during acute episodes, and during the intercurrent period the patient had features of chronic glomerular disease, including hypertension, proteinuria... | ['Acute Kidney Injury', 'Aphasia', 'Chronic Disease', 'Glomerulonephritis', 'Humans', 'Influenza, Human', 'Kidney Glomerulus', 'Male', 'Middle Aged', 'Purpura, Thrombotic Thrombocytopenic', 'Recurrence'] | 7,194,623 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['C23.550.291.500'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['A05.810.453.324.359'... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of hypoxia on function and morphology of in vitro frog gastric mucosa. | The effects of gaseous hypoxia and reoxygenation on oxynticopeptic (OPC) and surface mucous cells (SMC) were examined in in vitro bullfrog gastric fundic mucosae mounted in Ussing chambers. Forskolin-stimulated H+ secretion, transmucosal potential difference (PD), and electrical resistance (R) were monitored in tissues... | ['Animals', 'Bicarbonates', 'Cell Hypoxia', 'Colforsin', 'Electric Conductivity', 'Gastric Acid', 'Gastric Mucosa', 'In Vitro Techniques', 'Kinetics', 'Membrane Potentials', 'Microscopy, Electron', 'Oxygen', 'Rana catesbeiana', 'Time Factors'] | 1,312,792 | [['B01.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['G03.197.300', 'G04.270.300'], ['D02.455.849.291.300'], ['G01.358.500.249.277'], ['A12.200.307.603'], ['A03.556.875.875.440', 'A10.615.550.291'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Safety and efficacy of Soyo-san for the treatment of functional dyspepsia: A protocol for systematic review and meta-analysis. | BACKGROUND: Functional dyspepsia (FD) is a common condition characterized by gastrointestinal symptoms, such as abdominal fullness and epigastric pain. With the limitations of conventional Western medical treatments, symptoms often recur and lead to poor quality of life. Soyo-san (SYS) is a traditional herbal medicine ... | ['Drugs, Chinese Herbal', 'Dyspepsia', 'Humans', 'Meta-Analysis as Topic', 'Phytotherapy', 'Systematic Reviews as Topic'] | 32,991,453 | [['D20.215.784.500.350', 'D26.335'], ['C23.888.821.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500', 'E05.581.500.501', 'N05.715.360.325.515', 'N06.850.520.445.500'], ['E02.190.755'], ['L01.178.682.759.575']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Premorbid personality in first-onset psychosis. | The data presented are those from a two-year prospective study of 69 patients identified in the Nottingham field centre of the WHO Study of Determinants of Outcome of Severe Mental Disorders. Premorbid personality, childhood adjustment and adolescent adjustment were assessed at the patients' first presentation to psych... | ['Adolescent', 'Adult', 'Bipolar Disorder', 'Female', 'Humans', 'Male', 'Middle Aged', 'Paranoid Disorders', 'Personality Assessment', 'Personality Development', 'Personality Disorders', 'Psychiatric Status Rating Scales', 'Psychotic Disorders', 'Schizoid Personality Disorder', 'Schizophrenia', 'Schizophrenic Psycholog... | 8,173,823 | [['M01.060.057'], ['M01.060.116'], ['F03.084.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.700.450'], ['F04.513'], ['F01.752.747'], ['F03.675'], ['F04.711.513.653'], ['F03.700.675'], ['F03.675.700'], ['F03.700.750'], ['F04.824']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL. | Activation-induced cytidine deaminase (AID) is required for somatic hypermutation (SHM) and class switch recombination (CSR) of the immunoglobulin (Ig) gene. AID has been reported to be specifically expressed in the germinal center (GC). Follicular lymphoma (FL) cells are known to be exposed to GC reaction, as characte... | ['Aged', 'Aged, 80 and over', 'B-Lymphocytes', 'Cell Differentiation', 'Cell Line, Tumor', 'Cytidine Deaminase', 'Female', 'Humans', 'Immunoglobulin Variable Region', 'Lymphoma, Follicular', 'Male', 'Middle Aged', 'RNA, Messenger', 'Somatic Hypermutation, Immunoglobulin', 'Tumor Cells, Cultured'] | 14,990,977 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.277.151.486.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.650... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computer assisted biopsy of breast tumors. | In this paper we report our preliminary results of the development of a computer assisted system for breast biopsy. The system is based on tracked ultrasound images of the breast. A three dimensional ultrasound volume is constructed from a set of tracked B-scan images acquired with a calibrated probe. The system has be... | ['Biopsy', 'Breast', 'Breast Neoplasms', 'Calibration', 'Diagnosis, Computer-Assisted', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Phantoms, Imaging', 'Ultrasonography'] | 21,097,108 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E05.978.155'], ['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An analytical comparison of the information in sorted and non-sorted cosine-tuned spike activity. | Spike sorting is a technologically expensive component of the signal processing chain required to interpret population spike activity acquired in a neuromotor prosthesis. No systematic analysis of the value of spike sorting has been carried out, and little is known about the effects of spike sorting error on the abilit... | ['Action Potentials', 'Brain', 'Computer Simulation', 'Electroencephalography', 'Models, Neurological', 'Nerve Net', 'Neurons'] | 17,873,434 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['A08.186.211'], ['L01.224.160'], ['E01.370.376.300', 'E01.370.405.245'], ['E05.599.395.642'], ['A08.511'], ['A08.675', 'A11.671']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Application of facial nerve ENoG and MEP in the diagnosis and prognosis of facial nerve palsy]. | Electroneurography (ENoG), an objective electrophysiologic measurement of compound muscle action potentials (CMAPs), is used to assess the integrity of a peripheral motor nerve. This method has been used for many years. In our study using an electrophysiologic instrument (Medelec MS6), the stimulating electrode was pla... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Electric Stimulation', 'Electrodiagnosis', 'Evoked Potentials', 'Facial Nerve', 'Facial Paralysis', 'Female', 'Humans', 'Male', 'Prognosis'] | 1,831,696 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E05.723.402'], ['E01.370.405'], ['G07.265.216.500', 'G11.561.200.500'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.636.214'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The impact of quality filter for RNA-Seq. | BACKGROUND: With the emergence of large-scale sequencing platforms since 2005, there has been a great revolution regarding methods for decoding DNA sequences, which have also affected quantitative and qualitative gene expression analyses through the RNA-Sequencing technique. However, issues related to the amount of dat... | ['Corynebacterium pseudotuberculosis', 'Microcystis', 'RNA', 'Reproducibility of Results', 'Sequence Analysis, RNA'] | 25,796,604 | [['B03.510.024.250.600', 'B03.510.460.400.400.200.600'], ['B03.280.500', 'B03.440.475.100.500'], ['D13.444.735'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.393.760.710']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An Arabidopsis protein that interacts with the cytokinin-inducible response regulator, ARR4, implicated in the His-Asp phosphorylay signal transduction. | Previously, Arabidopsis thaliana was shown to possess a set of response regulators (ARR-series), which are implicated in the prokaryotic type of signal transduction mechanism, generally referred to as the His-Asp phosphorylay. Among them, ARR4 is a typical phospho-accepting response regulator, whose expression was rece... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Aspartic Acid', 'Cloning, Molecular', 'DNA-Binding Proteins', 'Histidine', 'Hybrid Cells', 'Molecular Sequence Data', 'Phosphorylation', 'Plant Proteins', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Signal Transduction', 'Substrate Specificit... | 9,771,897 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['E05.393.220'], ['D12.776.260'], ['D12.125.072.329', 'D12.125.142.308'], ['A11.251.600'], ['L01.453.245.667'], ['G02.111.665', 'G02.607.780', 'G03.796'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Suicide risk in primary care patients with major physical diseases: a case-control study. | CONTEXT: Most previous studies have examined suicide risk in relation to a single physical disease.OBJECTIVES: To estimate relative risk across a range of physical diseases, to assess the confounding effect of clinical depression and effect modification by sex and age, and to examine physical illness multimorbidity.DES... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Depression', 'Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Odds Ratio', 'Prevalence', 'Risk Factors', 'Sex Factors', 'Suicide', 'United Kingdom', 'Young Adult'] | 22,393,218 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F01.145.126.350'], ['C23.550.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['E... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Plasticity in mesophyll volume fraction modulates light-acclimation in needle photosynthesis in two pines. | Acclimation potential of needle photosynthetic capacity varies greatly among pine species, but the underlying chemical, anatomical and morphological controls are not entirely understood. We investigated the light-dependent variation in needle characteristics in individuals of Pinus patula Schlect. & Cham., which has 19... | ['Acclimatization', 'Light', 'Nitrogen', 'Photosynthesis', 'Pinus', 'Plant Leaves', 'Species Specificity', 'Xylem'] | 17,472,940 | [['G07.025.133', 'G16.012.500.133'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D01.268.604', 'D01.362.625'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['B01.650.940.800.575.912.625.875.777'], ['A18.024.812'], ['G1... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimation of Prognostic Marker Genes by Public Microarray Data in Patients with Ovarian Serous Cystadenocarcinoma. | PURPOSE: Lymphatic invasion (LI) is regarded as a predictor of the aggressiveness of ovarian cancer (OC). However, LI is not always the major determinant of long-term patient survival. To establish proper diagnosis and treatment for OC, we analyzed differentially expressed genes (DEGs) for patients with serous epitheli... | ['Cystadenocarcinoma, Serous', 'Databases, Genetic', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Microarray Analysis', 'Middle Aged', 'Ovarian Neoplasms', 'Prognosis', 'Regression Analysis', 'Retrospective Studies', 'Survival Rate'] | 27,189,279 | [['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.588.570'], ['M01.060.116.630'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.6... | ['Diseases [C]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Quantitative and qualitative assessment of pollen DNA metabarcoding using constructed species mixtures. | Pollen DNA metabarcoding-marker-based genetic identification of potentially mixed-species pollen samples-has applications across a variety of fields. While basic species-level pollen identification using standard DNA barcode markers is established, the extent to which metabarcoding (a) correctly assigns species identit... | ['Computational Biology', 'DNA Barcoding, Taxonomic', 'DNA, Plant', 'Pollen', 'Sequence Analysis, DNA', 'Species Specificity'] | 30,118,180 | [['H01.158.273.180', 'L01.313.124'], ['E05.393.542.249', 'E05.393.760.700.149'], ['D13.444.308.435'], ['A18.024.249.500.249.500'], ['E05.393.760.700'], ['G16.824']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Cutting and incision instruments (II). Incision instruments]. | In a surgeon's tool chest there are a variety of incision-making tools, some of frequent, common use in general or specialized surgery such as scalpels or scissors. There also exists an abundant quantity of instruments considered to pertain exclusively to determined surgical specialties. | ['Equipment Design', 'Surgical Instruments'] | 16,813,207 | [['E05.320'], ['E07.858.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An evaluation of wellness assessment visualizations for older adults. | BACKGROUND: Smart home technologies provide a valuable resource to unobtrusively monitor health and wellness within an older adult population. However, the breadth and density of data available along with aging associated decreases in working memory, prospective memory, spatial cognition, and processing speed can make ... | ['Aged', 'Aging', 'Cognition', 'Decision Making', 'Decision Support Techniques', 'Female', 'Focus Groups', 'Geriatric Assessment', 'Health Status', 'Humans', 'Male', 'Mental Health', 'Middle Aged', 'Qualitative Research', 'Telemetry', 'User-Computer Interface'] | 25,401,414 | [['M01.060.116.100'], ['G07.345.124'], ['F02.463.188'], ['F02.463.785.373'], ['E05.245', 'L01.313.500.750.190'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['I01.24... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Political implications of the named-nurse concept. | This paper considers the role of the named nurse as a linchpin in the commissioning/providing cycle. It argues that, whatever the impact on patient care, nurses should be wary of claims that the introduction of named nursing through government policy demonstrates esteem for British nursing. | ['Health Policy', 'Humans', 'Politics', 'Primary Nursing', 'Quality of Health Care', 'State Medicine', 'United Kingdom'] | 7,479,133 | [['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.738'], ['N02.421.533.760'], ['N04.761', 'N05.715'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
A novel oxygen-sensitive potassium current in rat carotid body type I cells. | 1. Hypoxic stimuli depolarize carotid body type I cells causing voltage-gated calcium influx. This study investigates the cause of this membrane depolarization. Isolated type I cells from neonatal (11-16 day) rat carotid bodies were used in the experiments. 2. Tetraethylammonium (TEA; 10 mM), 1 and 5 mM 4-aminopyridine... | ['4-Aminopyridine', 'Animals', 'Animals, Newborn', 'Calcium', 'Carotid Body', 'Cell Separation', 'Electrophysiology', 'Hypoxia', 'Membrane Potentials', 'Oxygen', 'Patch-Clamp Techniques', 'Potassium Channels', 'Rats', 'Tetraethylammonium Compounds'] | 9,051,577 | [['D02.092.080.060', 'D03.383.725.050.060'], ['B01.050'], ['B01.050.050.282'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A08.675.650.915.500.600.150', 'A08.800.950.500.600.150', 'A11.671.650.915.500.600.150'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['H01.158.344.528', 'H01.158.782.236... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. | This investigation was directed at characterizing some of the pharmacological properties of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol (O-823), a compound with high affinity for cannabinoid binding sites (Ki = 0.77 nM). In mouse vasa deferentia, O-823 behaved as a potent partial cannabinoid CB1 receptor agonist (E... | ['Analgesics', 'Animals', 'Benzoxazines', 'Binding, Competitive', 'Cyclohexanols', 'Dronabinol', 'Guinea Pigs', 'Injections, Intraperitoneal', 'Intestine, Small', 'Male', 'Mice', 'Morpholines', 'Muscle Contraction', 'Naphthalenes', 'Receptors, Cannabinoid', 'Receptors, Drug', 'Vas Deferens'] | 8,960,884 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D03.383.533.249', 'D03.633.100.209'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['D02.455.849.090.810'], ['B01.050.150.900.649.313.992.550'], ['E02.319.267.530.490'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Geodesics-based image registration: applications to biological and medical images depicting concentric ring patterns. | In many biological or medical applications, images that contain sequences of shapes are common. The existence of high inter-individual variability makes their interpretation complex. In this paper, we address the computer-assisted interpretation of such images and we investigate how we can remove or reduce these image ... | ['Algorithms', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Subtraction Technique'] | 23,880,058 | [['G17.035', 'L01.224.050'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.399.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A Ca2+-induced Ca2+ release mechanism involved in asynchronous exocytosis at frog motor nerve terminals. | The extent to which Ca2+-induced Ca2+ release (CICR) affects transmitter release is unknown. Continuous nerve stimulation (20-50 Hz) caused slow transient increases in miniature end-plate potential (MEPP) frequency (MEPP-hump) and intracellular free Ca2+ ([Ca2+]i) in presynaptic terminals (Ca2+-hump) in frog skeletal m... | ['Action Potentials', 'Animals', 'Calcium', 'Calcium Channel Blockers', 'Chelating Agents', 'Egtazic Acid', 'Evoked Potentials, Motor', 'Exocytosis', 'Fluorescent Dyes', 'Gallic Acid', 'Ion Channel Gating', 'Magnesium', 'Motor Neurons', 'Neurotransmitter Agents', 'Presynaptic Terminals', 'Ranidae', 'Ryanodine Receptor ... | 9,806,968 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['G07.265.216.500.385', 'G11.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy and safety of apatinib in advance osteosarcoma with pulmonary metastases: A single-center observational study. | This study was designed to evaluate the efficacy and safety of apatinib in patients with advanced osteosarcoma and pulmonary metastases following failed first-line chemotherapy.There were 10 patients with osteosarcoma pulmonary metastases, whose first-line chemotherapy had failed, had received apatinib treatment as a s... | ['Adolescent', 'Adult', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Bone Neoplasms', 'Child', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Osteosarcoma', 'Pyridines', 'Survival Analysis', 'Young Adult'] | 30,075,583 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selective caries removal with air abrasion. | The purpose of this study was to evaluate selective caries removal using an air-abrasive technique. Alumina powders, glass beads, crushed glass powders, and crushed powders of polycarbonate resin were applied to intact human enamel, dentin, and artificially demineralized dentin (caries-model dentin). Furthermore, the e... | ['Air', 'Air Pressure', 'Aluminum Oxide', 'Analysis of Variance', 'Dental Cavity Preparation', 'Dental Enamel', 'Dentin', 'Glass', 'Humans', 'Microscopy, Electron, Scanning', 'Particle Size', 'Polycarboxylate Cement'] | 9,863,444 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['G16.500.750.274.100', 'N06.230.300.100.185.100'], ['D01.056.050', 'D01.650.550.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E06.931.325'], ['A14.549.167.900.255'], ['A14.549.167.900.280'], ['J01.637.437'], ['B01.050.150.900.649.313.988.40... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Ifosfamide induced Fanconi syndrome. | Ifosfamide (IFA) is a powerful chemotherapeutic drug that is active against a variety of paediatric malignancies. However, renal toxicities such as haemorrhagic cystitis and Fanconi syndrome are major hazards that hinder its use in clinical practice. The authors present a case of a patient treated for Wilms' tumour wit... | ['Antineoplastic Agents, Alkylating', 'Child, Preschool', 'Fanconi Syndrome', 'Humans', 'Ifosfamide', 'Male'] | 22,669,992 | [['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['M01.060.406.448'], ['C12.777.419.815.450', 'C13.351.968.419.815.450', 'C16.320.831.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.728.650.730.243.250', 'D02.705.672.500.243.250', 'D03.383.533.500']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Double strandedness of nascent DNA of a higher plant (Vicia faba). | After a pulse of 5-10 min with [3H]thymidine, labeled DNA extracted from embryonic axes of Vicia seeds sedimented as a rather homogeneous peak at approx. 10S in an alkaline sucrose density gradient, as described in our previous paper ((1975) Biochim. Biophys. Acta 395, 314-321). The sedimentation pattern of the same pu... | ['Centrifugation, Density Gradient', 'DNA', 'DNA Replication', 'Molecular Weight', 'Plants'] | 963,083 | [['E05.181.724.336', 'E05.196.941.336'], ['D13.444.308'], ['G02.111.225', 'G05.226'], ['G02.494'], ['B01.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of various compounds on the degradation of hyaluronic acid by a myeloperoxidase system. | Myeloperoxidase in the presence of 0.7 mM hydrogen peroxide degrades hyaluronic by a mechanism which involves iron. Degradation is enhanced in the presence of chloride ion, which is attributed to the formation of hypochlorous acid. Myeloperoxidase-dependent degradation of hyaluronic acid is inhibited by superoxide dism... | ['Anti-Inflammatory Agents', 'Enzyme Activation', 'Granulocytes', 'Humans', 'Hyaluronic Acid', 'Hydrogen Peroxide', 'Hydroxyl Radical', 'In Vitro Techniques', 'Iron', 'Peroxidase', 'Sodium Chloride'] | 8,131,215 | [['D27.505.954.158'], ['G02.111.263', 'G03.328'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-range 1H-15N J couplings providing a method for direct studies of the structure and azide-tetrazole equilibrium in a series of azido-1,2,4-triazines and azidopyrimidines. | The selectively (15)N labeled azido-1,2,4-triazine 2*A and azidopyrimidine 4*A were synthesized by treating hydrazinoazines with (15)N-labeled nitrous acid. The synthesized compounds were studied by (1)H, (13)C, and (15)N NMR spectroscopy in DMSO, TFA, and DMSO/TFA solutions, where the azide-tetrazole equilibrium could... | ['Azides', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Nitrogen Isotopes', 'Protons', 'Pyrimidines', 'Reference Standards', 'Tetrazoles', 'Triazines'] | 23,751,069 | [['D01.625.100', 'D02.159'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D01.268.604.500', 'D01.362.625.500', 'D01.496.586'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D03.383.742'], ['E05.978.808'], ['D03.383.129.617'], ['D03.383.931']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diagnosis of pulmonary embolism]. | The diagnosis of pulmonary embolism (PE) is challenging because the symptoms are unspecific and an objective confirmation of the disease is required. Clinical symptoms and physical examination can be used to estimate the clinical probability of the disease used to interpret the results of the diagnostic tests. In patie... | ['Age Factors', 'Antifibrinolytic Agents', 'Contrast Media', 'Diagnosis, Differential', 'Female', 'Femoral Vein', 'Fibrin Fibrinogen Degradation Products', 'Humans', 'Lung', 'Physical Examination', 'Popliteal Vein', 'Pregnancy', 'Pregnancy Complications', 'Probability', 'Pulmonary Embolism', 'Radionuclide Imaging', 'Ri... | 17,626,317 | [['N05.715.350.075', 'N06.850.490.250'], ['D27.505.519.421.500', 'D27.505.954.502.270.463.091'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'], ['A07.015.908.314'], ['D12.776.124.270.300', 'D12.776.811.300.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E01.370.600'], ['A07.015.908.641'], ['G08... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A second high affinity HU binding site in the phage Mu transpososome. | The bacteriophage Mu in vitro transposition reaction proceeds through several higher order nucleoprotein intermediates (transpososomes). One of the requirements for complex assembly is the Escherichia coli sequence-independent DNA-binding protein, HU. This protein has an affinity for Mu transpososomes, which is at leas... | ['Bacterial Proteins', 'Bacteriophage mu', 'Binding Sites', 'DNA, Viral', 'DNA-Binding Proteins', 'Escherichia coli', 'Kinetics', 'Microscopy, Immunoelectron', 'Nucleic Acid Conformation', 'Nucleoproteins', 'Sequence Deletion'] | 8,195,202 | [['D12.776.097'], ['B04.123.150.500.260', 'B04.123.205.260', 'B04.280.090.500.260'], ['G02.111.570.120'], ['D13.444.308.568'], ['D12.776.260'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.515.402.625', 'E05.595.402.625'], ['G02.111.570.820.486', 'G05.360.580'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of splenectomy and glucocorticoids on survival and hepatic uptake of damaged red cells in the mouse. | We have studied the effects of splenectomy and glucocorticoids on the survival and sequestration of Heinz body-containing red blood cells (RBC-HZB). Mice were injected with phenylhydrazine damaged 51Cr labeled isologous red blood cells (RBCs). The spleen removed 36% and the liver 19% of the injected dose after 120 hrs.... | ['Animals', 'Cortisone', 'Erythrocytes', 'Heinz Bodies', 'Kupffer Cells', 'Liver', 'Male', 'Mice', 'Phagocytosis', 'Spleen', 'Splenectomy'] | 602,926 | [['B01.050'], ['D04.210.500.745.745.183', 'D06.472.040.585.478.195'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.118.290.330.315.335', 'A11.284.420.204.335', 'A15.145.229.334.330.340.335'], ['A11.329.372.588', 'A11.627.482.588', 'A11.733.397.588', 'A15.382.670.522.588', 'A15.382.680.397.588'], ['A03.620']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate. | Macrophage polarization contributes to a number of human pathologies. This is exemplified for tumor-associated macrophages (TAMs), which display a polarized M2 phenotype, closely associated with promotion of angiogenesis and suppression of innate immune responses. We present evidence that induction of apoptosis in tumo... | ['Anti-Inflammatory Agents', 'Apoptosis', 'Cell Line, Tumor', 'Cell Polarity', 'Cell Survival', 'Coculture Techniques', 'Cytokines', 'Humans', 'Lysophospholipids', 'Macrophage Activation', 'Macrophages', 'NF-kappa B', 'Neoplasms', 'Phosphotransferases (Alcohol Group Acceptor)', 'Sphingosine', 'Staurosporine'] | 17,652,460 | [['D27.505.954.158'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.250'], ['G04.346'], ['E05.481.500.374'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.755.375.760.550'], ['G12.287.500'], ['A11.329.372', 'A11.627.482', 'A11.733.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pressure injury prevalence and predictors among older adults in the first 36 hours of hospitalisation. | AIMS AND OBJECTIVE: To describe the prevalence and predictors of pressure injuries among older adults with limited mobility, within the first 36 hr of their hospital admission in Australia.BACKGROUND: Pressure injuries are significant health, safety and quality of care issues for patients and healthcare organisations. ... | ['Aged', 'Aged, 80 and over', 'Australia', 'Early Diagnosis', 'Female', 'Hospitalization', 'Humans', 'Male', 'Pressure Ulcer', 'Prevalence', 'Prospective Studies', 'Risk Assessment'] | 31,216,388 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['E01.390'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.893.665'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E0... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
RECG maintains plastid and mitochondrial genome stability by suppressing extensive recombination between short dispersed repeats. | Maintenance of plastid and mitochondrial genome stability is crucial for photosynthesis and respiration, respectively. Recently, we have reported that RECA1 maintains mitochondrial genome stability by suppressing gross rearrangements induced by aberrant recombination between short dispersed repeats in the moss Physcomi... | ['Bryopsida', 'Chloroplast Proteins', 'DNA Helicases', 'Genome, Mitochondrial', 'Genomic Instability', 'Mitochondrial Proteins', 'Plants'] | 25,769,081 | [['B01.650.940.800.575.137.500'], ['D12.776.765.199'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['G05.360.340.360'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['D12.776.575'], ['B01.650']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of temperature on mineralisation of petroleum in contaminated Antarctic terrestrial sediments. | Although petroleum contamination has been identified at many Antarctic research stations, and is recognized as posing a significant threat to the Antarctic environment, full-scale in situ remediation has not yet been used in Antarctica. This is partly because it has been assumed that temperatures are too low for effect... | ['Alkanes', 'Antarctic Regions', 'Biodegradation, Environmental', 'Carbon Dioxide', 'Carbon Radioisotopes', 'Chromatography, Gas', 'Environmental Monitoring', 'Geologic Sediments', 'Kinetics', 'Petroleum', 'Regression Analysis', 'Temperature', 'Water Pollutants, Chemical'] | 12,781,231 | [['D02.455.326.146'], ['Z01.158'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['E05.196.181.349'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['G01.374.661', 'G02.111.4... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Low-cost materials yield high resolution assessment of anatomic knowledge in surgical residents. | INTRODUCTION: Knowledge of anatomy is essential for surgeons. We sought to determine whether it is possible to effectively assess and differentiate the anatomic knowledge of general surgery residents, using pieces of fabric and yarn.METHODS: Postgraduate years 2, 3, and 4 general surgery residents were assessed during ... | ['Anatomy', 'Clinical Competence', 'Education, Medical, Graduate', 'Educational Measurement', 'General Surgery', 'Humans', 'Internship and Residency'] | 30,922,547 | [['H01.158.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.337.350', 'I02.358.399.350'], ['I02.399'], ['H02.403.810.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750']] | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Ultrasonic extraction of oil from tobacco (Nicotiana tabacum L.) seeds. | The ultrasonic extraction (UE) of oil from the seeds of a semi-oriental tobacco (Nicotiana tabacum L.) plant strain by using n-hexane and petroleum ether was studied at different temperatures and seeds-to-solvent ratios. The oil yield depended on the seed comminution, the extraction temperature, the seeds-to-solvent ra... | ['Plant Oils', 'Seeds', 'Solvents', 'Tobacco', 'Ultrasonics'] | 17,142,082 | [['D10.627.700', 'D20.215.784.750'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D27.720.844'], ['B01.650.940.800.575.912.250.908.500.900'], ['H01.671.031.849']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Non-Hodgkin's lymphoma of the stomach. A case report]. | Clinical supervision diffuse large B-cell lymphoma of the stomach at the patient of young age is presented. Difficulties of the differential diagnostics of lymphom have been caused by macroscopical polyphormism. With the purpose of verification of disease are used the chromoendoscopy and immunohistochemical research. | ['Adult', 'Biopsy', 'Diagnosis, Differential', 'Female', 'Gastroscopy', 'Humans', 'Immunohistochemistry', 'Lymphoma, Large B-Cell, Diffuse', 'Stomach Neoplasms', 'Young Adult'] | 20,623,961 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Appearance and elaboration of the ethylene receptor family during land plant evolution. | Ethylene is perceived following binding to endoplasmic reticulum-localized receptors, which in Arabidopsis thaliana, include ETR1, ERS1, EIN4, ETR2, and ERS2. These receptors fall into two subfamilies based on conservation of features within their histidine kinase domain. Subfamily 1 contains ETR1 and ERS1 whereas subf... | ['Arabidopsis Proteins', 'Biological Evolution', 'Bryopsida', 'Plant Proteins', 'Receptors, Cell Surface'] | 25,682,121 | [['D12.776.765.149'], ['G05.045', 'G16.075'], ['B01.650.940.800.575.137.500'], ['D12.776.765'], ['D12.776.543.750']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An intervention program for ADHD in patients with substance use disorders: preliminary results of a field trial. | The comorbidity of attention deficit hyperactivity disorder (ADHD) is frequently not well recognized in substance abuse treatment institutions in The Netherlands. As a consequence, patients with substance use disorder (SUD) and ADHD often receive suboptimal treatment. To prevent every treatment center from having to in... | ['Activities of Daily Living', 'Adult', 'Attention Deficit Disorder with Hyperactivity', 'Clinical Protocols', 'Education', 'Family', 'Humans', 'Interview, Psychological', 'Peer Group', 'Psychiatric Status Rating Scales', 'Psychotherapy', 'Social Support', 'Substance-Related Disorders'] | 16,616,170 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['F03.625.094.150'], ['E02.183', 'N05.715.360.330.125'], ['I02'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['F01.829.316.483'], ['F04.711.513.653'], ['F04.754'], ['I01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Bocavirus Viremia and Hepatitis in an Immunocompetent Child. | BACKGROUND: So far, many studies have shown that Human Bocavirus ( HBoV) is the main pathogen of the respiratory tract. Until now, there is no study that proves the association between HBoV and hepatitis. HBoV viremia/DNAemia has been associated closely with acute primary infection and moderate-to-severe illness but, m... | ['Abdominal Pain', 'Child, Preschool', 'Female', 'Fever', 'Hepatitis A', 'Human bocavirus', 'Humans', 'Parvoviridae Infections', 'Pharynx', 'Respiratory Tract Infections', 'Turkey', 'Viremia', 'Vomiting'] | 28,443,581 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.406.448'], ['C23.888.119.344'], ['C01.925.440.420', 'C01.925.782.687.359.500', 'C06.552.380.705.422'], ['B04.280.580.650.085.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.256.700'], ['A03.556.750', 'A04.623', 'A14.724'], ['C01.748', 'C08.730'], ... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Sleep disturbances in patients with generalized anxiety: a clinical and EEG sleep study]. | All night EEG sleep recordings and clinical evaluations of sleep were performed in order to compare patients with generalized anxiety and normal controls. Patients were selected according to DSM III-R criteria and went through a two weeks phase treatment with placebo before the sleep evaluation. As compared to normals,... | ['Adult', 'Analysis of Variance', 'Anxiety Disorders', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sleep'] | 1,767,708 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F03.080'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.830.855', 'G11.561.803']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells. | We recently reported that cADP-ribose (cADPR) and ADP-ribose (ADPR) play an important role in the regulation of the Ca(2+)-activated K(+) (K(Ca)) channel activity in coronary arterial smooth muscle cells (CASMCs). The present study determined whether these novel signaling nucleotides participate in 11,12-epoxyeicosatri... | ['8,11,14-Eicosatrienoic Acid', 'Adenosine Diphosphate Ribose', 'Animals', 'Arachidonic Acid', 'Arterioles', 'Cattle', 'Coronary Vessels', 'Hydroxyeicosatetraenoic Acids', 'In Vitro Techniques', 'Kinetics', 'Muscle, Smooth, Vascular', 'Nitroprusside', 'Patch-Clamp Techniques', 'Potassium Channels, Calcium-Activated', '... | 11,893,556 | [['D10.251.355.255.207'], ['D03.633.100.759.646.138.124.070.125', 'D09.408.620.569.070.125', 'D13.695.667.138.124.070.125', 'D13.695.827.068.124.070.125', 'D13.695.827.708.070.125'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['A07.015.114.060', 'A07.015.461.080'], ['B01.050.150.900.649.313.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low molecular weight PEIs modified by hydrazone-based crosslinker and betaine as improved gene carriers. | Low-molecular-weight polyethyleneimine (LMW PEI) exhibits poorer transfection efficiency but lower cytotoxicity compared to high-molecular-weight polyethyleneimine (such as PEI 25kDa). To enhance the gene transfection performance of LMW PEI, we herein demonstrate a new strategy for modifying LMW PEI. A crosslinker cont... | ['Animals', 'Betaine', 'Genetic Vectors', 'HEK293 Cells', 'HeLa Cells', 'Hemolysis', 'Humans', 'Hydrazones', 'Molecular Weight', 'Polyethyleneimine', 'Proton Magnetic Resonance Spectroscopy', 'Rabbits'] | 25,092,585 | [['B01.050'], ['D02.092.877.883.077', 'D02.675.276.125'], ['G05.360.337'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.288'], ['G02.494'], ['D02.455.326.271.665.550.600',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Research on living tree volume forecast based on PSO embedding SVM]. | In order to establish volume model,living trees have to be fallen and be divided into many sections, which is a kind of destructive experiment. So hundreds of thousands of trees have been fallen down each year in China. To solve this problem, a new method called living tree volume accurate measurement without falling t... | ['Algorithms', 'China', 'Nonlinear Dynamics', 'Support Vector Machine', 'Trees'] | 24,783,556 | [['G17.035', 'L01.224.050'], ['Z01.252.474.164'], ['E05.599.850', 'H01.548.675'], ['G17.035.250.500.500.500', 'L01.224.050.375.530.500.500'], ['B01.650.915']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
Oxidative stress in rats experimentally infected by Sporothrix schenckii. | The aim of this study was to evaluate whether oxidative stress occurs in rats experimentally infected by Sporothrix schenckii, and its possible effect on disease pathogenesis. Thirty rats were divided into two groups: the group A (uninfected, n = 18) and the group B (infected by S. schenckii, n=21). Blood samples were ... | ['Animals', 'Antioxidants', 'Biomarkers', 'Catalase', 'Cytokines', 'Disease Models, Animal', 'Granuloma', 'Hyperplasia', 'Inflammation', 'Interferon-gamma', 'Interleukin-6', 'Lipid Peroxidation', 'Liver', 'Male', 'Oxidative Stress', 'Rats', 'Serum', 'Spleen', 'Splenic Diseases', 'Sporothrix', 'Sporotrichosis', 'Superox... | 28,286,151 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D23.101'], ['D08.811.682.732.332'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C15.604.515.292', 'C23.550.382'], ['C23.550.444'], ['C23.550.470'], ['D12.644.276.374.440.893', 'D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oligolysine-conjugated zinc(II) phthalocyanines as efficient photosensitizers for antimicrobial photodynamic therapy. | A series of zinc(II) phthalocyanines conjugated with an oligolysine chain (n=2, 4, and 8) were synthesized and characterized by using various spectroscopic methods. As shown by using UV/Vis and fluorescence spectroscopic methods, these compounds were nonaggregated in N,N-dimethylformamide, and gave a weak fluorescence ... | ['Animals', 'Anti-Infective Agents', 'Antiviral Agents', 'Cell Line', 'Chemistry Techniques, Synthetic', 'Dogs', 'Humans', 'Indoles', 'Influenza A Virus, H1N1 Subtype', 'Madin Darby Canine Kidney Cells', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Organometallic Compounds', 'Photochem... | 24,799,418 | [['B01.050'], ['D27.505.954.122'], ['D27.505.954.122.388'], ['A11.251.210'], ['E05.197', 'J01.897.836.249'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['B04.820.480.968.405.400.214'], ['A11.251.210.827', 'A11.436.589'], ['B03.300.390.400.800.750.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Study on the kinetic properties of phosphor in deoxycholate aggregates by phosphorescent quenching methodology. | Owing to the unique molecular structure and aggregate behaviors in aqueous solution, dihydroxy bile salts can provide phosphorescent probe with a special microenvironment in which the room temperature phosphorescence of probe can be detected in the presence of dissolved oxygen. It, however, is not very clear how the bi... | ['Bile Acids and Salts', 'Deoxycholic Acid', 'Fluorescent Dyes', 'Kinetics', 'Luminescent Measurements', 'Oxygen', 'Quinolines'] | 17,570,675 | [['D04.210.500.105'], ['D04.210.500.105.225.272', 'D04.210.500.221.430.342'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G01.374.661', 'G02.111.490'], ['E05.196.712.516'], ['D01.268.185.550', 'D01.362.670'], ['D03.633.100.810']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA-restricted responses to M and N determinants in the primed lymphocyte test. | We have studied the role of MNSs determinants in the primed lymphocyte test (PLT). The data demonstrate that incompatibility associated with the M or N antigens causes HLA-restricted proliferative responses in PLT. Responses to the M or N determinants required the presence of the same HLA-A antigen(s) on both the stimu... | ['Cytotoxicity Tests, Immunologic', 'Epitopes', 'HLA Antigens', 'Humans', 'Lymphocyte Culture Test, Mixed', 'MNSs Blood-Group System'] | 6,173,363 | [['E01.370.225.812.160', 'E05.200.812.160', 'E05.478.594.160', 'E05.940.245'], ['D23.050.550'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.385.475', 'E05.200.812.385.475', 'E05.478.594.385.429'], ['D23.050.301.290.606', 'D23.050.705.230.606']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of chemotherapy treatment on hemostasis of patients with lung cancer]. | Chemotherapy is known to raise the risk of developing thrombotic complications. The aim of our work is to study the system of hemostasis in patients with the lung cancer under chemotherapy treatment. 61 patients were examined (40 men, 21 women) between the ages of 32 and 75 years (the principal group). Chemotherapy was... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Blood Platelets', 'Female', 'Hemostasis', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging'] | 18,830,029 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['A11.118.188', 'A15.145.229.188'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E01.789.625']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of UV scanning techniques in the identification of serum constituents separated by high-performance liquid chromatography. | Serum constituents separated by the reversed-phase partition mode of high-performance liquid chromatography were identified by using a stopped-flow UV scanning technique. This method of peak identification eliminates post-chromatographic sample handling. Results from UV scanning were correlated with those obtained from... | ['Chromatography, High Pressure Liquid', 'Depression', 'Humans', 'Kinetics', 'Purine-Nucleoside Phosphorylase', 'Spectrophotometry, Ultraviolet', 'Urate Oxidase', 'Xanthine Oxidase'] | 102,655 | [['E05.196.181.400.300'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D08.811.913.400.725.800'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D08.811.682.943'], ['D08.811.682.047.928']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First report on mould and mycotoxin contamination of pistachios sampled in Algeria. | Mycotoxin contamination of pistachios represents a serious food safety hazard. The aim of this study was to evaluate fungal contamination and aflatoxin (AF) and ochratoxin A (OTA) occurrence in pistachio sampled in Algeria and to study the mycotoxigenic capacities of the isolates. A total of 31 pistachio samples were c... | ['Aflatoxins', 'Algeria', 'Fungi', 'Ochratoxins', 'Pistacia'] | 20,556,658 | [['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['Z01.058.266.104'], ['B01.300'], ['D03.383.663.283.446.800.500', 'D03.633.100.150.446.800.500', 'D23.946.587.697'], ['B01.650.940.800.575.912.250.044.555']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Pulmonary artery banding in complete atrioventricular septal defect. | OBJECTIVES: To analyze outcomes after pulmonary artery banding (PAB) in complete atrioventricular septal defect (AVSD), with a focus on surgical pathway outcome and timing, survival, and atrioventricular valve function.METHODS: PAB was performed in 50 of 474 infants (11%) from 28 institutions between 2012 and 2018 at a... | ['Cohort Studies', 'Echocardiography', 'Female', 'Heart Septal Defects', 'Humans', 'Infant', 'Male', 'Pulmonary Artery', 'Reoperation', 'Survival Rate', 'Treatment Outcome'] | 31,669,019 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.240.400.560', 'C14.280.400.560', 'C16.131.240.400.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A07.015.114.715'], ['E04.690'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Blood volume pulse biofeedback in the treatment of migraine headache: a controlled evaluation. | In order to evaluate the specific effects of blood volume pulse (BVP) biofeedback in the treatment of migraine headaches, 21 female migraine patients were randomly assigned to one of three experimental conditions: temporal artery constriction feedback, temporal artery dilation feedback, or waiting list. Biofeedback tra... | ['Adolescent', 'Adult', 'Biofeedback, Psychology', 'Female', 'Humans', 'Middle Aged', 'Migraine Disorders', 'Pulse', 'Random Allocation', 'Temporal Arteries', 'Vasoconstriction', 'Vasodilation'] | 6,671,106 | [['M01.060.057'], ['M01.060.116'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.546.399.750'], ['E01.370.370.380.650', 'G09.330.380.750'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A rare tumor of the lung in childhood--inflammatory myofibroblastic tumor]. | Inflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm, mainly involving the lungs of the children. It represents 0.7% of all lung tumors. It was first described by Brunn in 1939.2 Diagnosis is very difficult and often only possible after resection of the tumor. We would like to present a case of pulmonary ... | ['Adolescent', 'Biopsy, Needle', 'Female', 'Humans', 'Lung Neoplasms', 'Plasma Cell Granuloma, Pulmonary', 'Rare Diseases', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 24,720,152 | [['M01.060.057'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C08.381.60... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An environmental hazard assessment of low-level dermal exposure to hexavalent chromium in solution among chromium-sensitized volunteers. | To evaluate the potential for elicitation of allergic contact dermatitis from contact with standing water in the environment, 26 persons known to be allergic to hexavalent chromium [Cr(VI)] were exposed to 25 to 29 mg/L Cr(VI) by immersion of one arm for 30 minutes per day on 3 consecutive days in a potassium dichromat... | ['Biopsy', 'Chromium', 'Dermatitis, Allergic Contact', 'Dermatitis, Occupational', 'Dose-Response Relationship, Drug', 'Hazardous Substances', 'Humans', 'Patch Tests', 'Patient Selection', 'Potassium Dichromate', 'Risk Assessment', 'Skin', 'Solutions'] | 10,091,138 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['C17.800.174.255.100', 'C17.800.815.255.100', 'C20.543.418.150'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fibroma of tendon sheath. A light and electron-microscopic study of 6 cases. | The clinical picture, the light and electron microscopic appearance, and the histochemical findings are described in six cases of fibroma of tendon sheath. The ages at onset for the four men and two women range between 16 and 54 years. The lesions were well circumscribed, rounded or oval, and had a diameter of about 1 ... | ['Adolescent', 'Adult', 'Female', 'Fibroma', 'Humans', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Tendons'] | 6,516,840 | [['M01.060.057'], ['M01.060.116'], ['C04.557.450.565.590.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'], ['A02.880']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
PP2Cä inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer. | Although nuclear type 2C protein phosphatase (PP2Cä) has been demonstrated to be pro-oncogenic with an important role in tumorigenesis, the underlying mechanisms that link aberrant PP2Cä levels with cancer development remain elusive. Here, we found that aberrant PP2Cä activity decreases p53 acetylation and its transcri... | ['Acetylation', 'Animals', 'Apoptosis', 'Ataxia Telangiectasia Mutated Proteins', 'BRCA1 Protein', 'Breast Neoplasms', 'Cell Cycle Proteins', 'Cell Line, Tumor', 'DNA Damage', 'E1A-Associated p300 Protein', 'Female', 'Humans', 'MCF-7 Cells', 'Mice', 'Mice, Nude', 'Phosphorylation', 'Protein Phosphatase 2C', 'Signal Tra... | 31,663,018 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['G04.146.954.035'], ['D08.811.913.696.620.682.700.097', 'D12.776.157.687.125', 'D12.776.660.720.125'], ['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Soybean ATP sulfurylase, a homodimeric enzyme involved in sulfur assimilation, is abundantly expressed in roots and induced by cold treatment. | Soybeans are a rich source of protein and a key feed ingredient in livestock production, but lack sufficient levels of cysteine and methionine to meet the nutritional demands of swine or poultry as feed components. Although engineering the sulfur assimilatory pathway could lead to increased sulfur-containing amino acid... | ['Chloroplasts', 'Cloning, Molecular', 'Cold Temperature', 'DNA, Complementary', 'Dimerization', 'Escherichia coli', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Multigene Family', 'Plant Proteins', 'Plant Roots', 'Protein Structure, Quate... | 16,684,499 | [['A11.284.430.214.190.875.700.140'], ['E05.393.220'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G02.206', 'G03.230'], ['B03.440.450.425.325.300... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Vaccination with human pluripotent stem cells generates a broad spectrum of immunological and clinical responses against colon cancer. | The history of immunizing with embryonic materials to generate an antitumor immune response dates back to a century ago. The premise is that cancer cells share the expression of oncofetal antigens with embryonic materials and that the immune response against these antigens in the embryonic tissues is cross-protective a... | ['Adenocarcinoma', 'Animals', 'Autoimmunity', 'Cell Differentiation', 'Cell Line', 'Colonic Neoplasms', 'Female', 'Humans', 'Immunotherapy', 'Mice', 'Mice, Inbred BALB C', 'Pluripotent Stem Cells', 'Spleen', 'Vaccination', 'Xenograft Model Antitumor Assays'] | 19,816,950 | [['C04.557.470.200.025'], ['B01.050'], ['G12.450.192'], ['G04.152'], ['A11.251.210'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['B01.050.150.900.649.3... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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