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Soft tissue tumours and tumour like lesions - a demographic and clinicopathologic study of 461 cases from different regions of Bangladesh. | Soft tissue tumours and tumour like lesions are relatively rare. They pose diagnostic difficulty due to wide morphological variation as well as overlapping clinical and pathological features. The relative frequency of soft tissue tumours varies throughout world. This study was undertaken to find out the distribution of... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bangladesh', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Soft Tissue Neoplasms'] | 25,725,680 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.252.245.131'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C04.588.839']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
NMR imaging of forearms in healthy volunteers and patients with giant-cell tumor of bone. | Serial proton nuclear magnetic resonance (NMR) images of distal upper extremities were obtained in four healthy volunteers and four patients with giant cell tumor of the distal radius. The steady-state-free-precession (SSFP) data collection technique and an 8-cm bore superconducting magnet (1.44 tesla) were used. All i... | ['Adult', 'Biopsy', 'Bone Neoplasms', 'Female', 'Forearm', 'Giant Cell Tumors', 'Humans', 'Magnetic Resonance Spectroscopy', 'Male', 'Radiography', 'Radius', 'Tomography'] | 7,100,470 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.149', 'C05.116.231'], ['A01.378.800.585'], ['C04.557.450.565.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['E01.370.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of steroidal and non-steroidal antiinflammatory drugs on chronic muscle inflammation. | Zymosan (400 microgram) and thioglycollate medium (0.1 ml of 2.4% w/v) have each been shown to induce a chronic inflammation when injected into the hamstring muscle of the mouse. The inflammation is characterized by an increase in muscle weight and N-acetylglycosaminidase concentrations. The response is not inhibited b... | ['Acetylglucosaminidase', 'Animals', 'Anti-Inflammatory Agents', 'Chronic Disease', 'Dexamethasone', 'Female', 'Hydrocortisone', 'Mice', 'Muscles', 'Myositis', 'Naproxen', 'Prednisolone'] | 6,104,695 | [['D08.811.277.450.483.180.500'], ['B01.050'], ['D27.505.954.158'], ['C23.550.291.500'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['B01.050.150.900.649.313.992.635.505.500'], ['A02.633', 'A10.690'], ['C05.651.594', 'C1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA antigens and islet cell antibodies in gestational diabetes. | The HLA antigens of 136 patients with gestational diabetes are compared with control populations. No significant variations are observed in their frequencies, particularly for those antigens associated with Type 1 diabetes mellitus. Islet cell antibodies have also been studied in the serum of 52 of these patients and 2... | ['Adult', 'Antibodies', 'Autoimmune Diseases', 'Diabetes Mellitus', 'Female', 'HLA Antigens', 'Histocompatibility Antigens Class II', 'Humans', 'Islets of Langerhans', 'Phenotype', 'Pregnancy', 'Pregnancy in Diabetics'] | 7,031,028 | [['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C20.111'], ['C18.452.394.750', 'C19.246'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Direct, catalytic synthesis of carbapenams via cycloaddition/rearrangement cascade reaction: unexpected acetylenes' structure effect. | Reactions of acetylenes derived from glyceraldehyde and propargyl aldehyde show remarkable reactivity in Kinugasa cycloaddition/rearrangement cascade process catalyzed by Cu(I) ion. Reactions proceed by formation of a rigid dinuclear copper(I) complex in which each copper ion is coordinated to one or both oxygen atoms ... | ['Acetylene', 'Alkynes', 'Catalysis', 'Copper', 'Cycloaddition Reaction', 'Glyceraldehyde', 'Molecular Structure', 'Propanols', 'Stereoisomerism'] | 20,961,063 | [['D02.455.326.397.259'], ['D02.455.326.397'], ['G02.130'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.197.406', 'J01.897.836.249.374'], ['D02.047.587', 'D09.947.875.894.449'], ['G02.111.570', 'G02.466'], ['D02.033.755'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fast apple (Malus x domestica) and tobacco (Nicotiana tobacum) leaf polyphenol oxidase activity assay for screening transgenic plants. | A spectrophotometric assay method for the analysis of polyphenol oxidase (PPO), in apple and tobacco leaves, has been optimized to increase efficiency in the screening of large numbers of transgenic plants. Crude protein extracts from leaf punches were prepared in a FastPrep homogenizer. The addition of Triton X-100 du... | ['Biotechnology', 'Catechol Oxidase', 'Fruit', 'Kinetics', 'Plant Leaves', 'Plants, Genetically Modified', 'Plants, Toxic', 'Rosales', 'Spectrophotometry', 'Tobacco'] | 11,141,262 | [['H01.158.550', 'J01.897.120'], ['D08.811.682.690.708.125'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G01.374.661', 'G02.111.490'], ['A18.024.812'], ['B01.650.520', 'B05.620.600'], ['B01.650.660'], ['B01.650.940.800.575.912.250.859.937'], ['E05.196.712.726', 'E05.196.867.826'], ['B01.650.940.800.575.912.25... | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Association of VDR gene polymorphisms and 22 bp deletions in the promoter region of TLR2Ä22 (-196-174) with increased risk of pulmonary tuberculosis: A case-control study in tea garden communities of Assam. | BACKGROUND: A high number of pulmonary tuberculosis (PTB) cases have been reported from tea garden communities of Assam. Till date, no molecular epidemiological study was performed to investigate the association of candidate gene(s) with the risk PTB in this region. The present case-control study was aimed to investiga... | ['Adult', 'Case-Control Studies', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'India', 'Male', 'Middle Aged', 'Molecular Epidemiology', 'Receptors, Calcitriol', 'Toll-Like Receptor 2', 'Tuberculosis, Pulmonary', 'Young Adult'] | 29,727,015 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['E05.318.416', 'E05.393.522', 'H01.158.201.636.475.500', 'H01.158.273.343.595.475.500', 'H0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Pregnancy, delivery, and postpartum experiences of fifty-four women with ostomies. | OBJECTIVE: The pregnancy, labor, and delivery experiences of women with ostomies are described.DESIGN: Patient survey.SETTINGS AND SUBJECTS: Distribution of surveys to women with these experiences: patients of the Cleveland Clinic Foundation, referrals by networking of ET nurses, and distribution of surveys at a nation... | ['Aged', 'Delivery, Obstetric', 'Female', 'Humans', 'Ileostomy', 'Middle Aged', 'Nursing Methodology Research', 'Postpartum Period', 'Pregnancy', 'Pregnancy Complications', 'Surveys and Questionnaires', 'Urinary Diversion'] | 9,224,023 | [['M01.060.116.100'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['M01.060.116.630'], ['H01.770.644.145.390.634', 'H02.478.395.634', 'N04.590.233.508.613.634'], ['G08.686.702'], ['G08.686.784.769'], ['C13.703'], ['E05.318.308.980', 'N05.715.360.300.800', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Closure of the petrous apex of the temporal bone with ionomeric cement following translabyrinthine removal of an acoustic neuroma. | When performing translabyrinthine surgery for acoustic neuroma, the surgeon opens the cerebrospinal fluid space. To prevent the development of post-operative meningitis, the surgical defect should be closed reliably in a watertight fashion. To date, this has been done with success in 12 patients altogether using a self... | ['Bone Cements', 'Follow-Up Studies', 'Humans', 'Meningitis', 'Neuroma, Acoustic', 'Petrous Bone', 'Postoperative Complications'] | 8,169,499 | [['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.614'], ['C04.557.465.625.650.595.610', 'C04.557.580.600.610.595.610', '... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Lead-induced convulsions in young infants--a case history and the role of GABA and sodium valproate in the pathogenesis and treatment. | A detailed case history of lead poisoning in a young infant is presented. Attention is directed towards the nature of the induced convulsions observed in such cases and the possible role of the GABAergic neuroinhibitory system. In vitro data demonstrating direct lead-GABA interaction is presented and sodium valproate, ... | ['Chemical Phenomena', 'Chemistry', 'Citric Acid Cycle', 'Humans', 'Infant', 'Lead', 'Lead Poisoning', 'Male', 'Seizures', 'Valproic Acid', 'gamma-Aminobutyric Acid'] | 6,436,320 | [['G02'], ['H01.181'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D01.268.556.435', 'D01.552.544.435'], ['C25.723.522.750'], ['C10.597.742', 'C23.888.592.742'], ['D02.241.081.944.509.900', 'D10.251.400.895.593.900'], ['D02.241.081.114.500.350', 'D1... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Chemical modification of human neutrophil membrane proteins: effect on fMet-Leu-Phe binding and function. | [3H]fMet-Leu-Phe binding to human neutrophil membrane proteins was shown to be inhibited by pretreatment of membranes with the histidine-preferring reagent diethylpyrocarbonate in a concentration- and time-dependent fashion. The inhibition was partially reversed by hydroxylamine and was affected by pH. The pH profile f... | ['Diethyl Pyrocarbonate', 'Histidine', 'Humans', 'Hydrogen-Ion Concentration', 'Hydroxylamine', 'Hydroxylamines', 'Imidazoles', 'Membrane Proteins', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Protein Binding', 'Receptors, Formyl Peptide', 'Receptors, Immunologic', 'Superoxides'] | 3,011,934 | [['D02.241.081.420.750.250'], ['D12.125.072.329', 'D12.125.142.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D01.625.062.437'], ['D02.092.570'], ['D03.383.129.308'], ['D12.776.543'], ['D02.886.030.676.450.440', 'D12.125.072.050.685.445', 'D12.125.142.666.500', 'D12.125.166.676.450.440', 'D12.64... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis, analgesic and anti-inflammatory activities of novel 3-(4-acetamido-benzyl)-5-substituted-1,2,4-oxadiazoles. | A series of 3-(4-acetamido-benzyl)-5-substituted-1,2,4-oxadiazoles (7a-7n) were synthesized and screened for analgesic and in vivo anti-inflammatory activities using acetic acid writhing in mice model and carrageenan-induced paw oedema method in mice, respectively. The analgesic activity of compounds 7i and 7m is super... | ['Analgesics', 'Animals', 'Anti-Inflammatory Agents', 'Drug Evaluation, Preclinical', 'Edema', 'Mice', 'Oxadiazoles', 'Pain', 'Structure-Activity Relationship'] | 18,621,449 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.954.158'], ['E05.290.750', 'E05.337.550'], ['C23.888.277'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.383.129.462.580'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trimethylphosphine binding to horse-heart and sperm-whale myoglobins. Kinetics, proton magnetic resonance assignment and nuclear Overhauser effect investigation of the heme pocket. | Two-dimensional nuclear magnetic resonance techniques have been used to assign resonances corresponding to the heme pocket and several other residues of horse heart and sperm whale myoglobins ligated by trimethylphosphine. The assignment procedure was based mainly on the nuclear Overhauser effect connectivities with th... | ['Animals', 'Binding Sites', 'Heme', 'Horses', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Myoglobin', 'Phosphines', 'Protein Conformation', 'Species Specificity', 'Spectrophotometry', 'Whales'] | 8,513,790 | [['B01.050'], ['G02.111.570.120'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.050.150.900.649.313.984.235.472'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['D01.695.525', 'D02.705.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coexistence of Takayasu's arteritis with familial Mediterranean fever. | Familial Mediterranean fever (FMF) is the most common autoinflammatory disease characterized by recurrent self-limited attacks of fever, accompanied with peritonitis, pleuritis or arthritis. It is well known that FMF may coexist with vasculitic pathologies, especially with those involving small and medium vessels. Amon... | ['Adrenal Cortex Hormones', 'Antibodies, Monoclonal', 'Colchicine', 'Drug Resistance', 'Familial Mediterranean Fever', 'Humans', 'Immunosuppressive Agents', 'Infliximab', 'Male', 'Severity of Illness Index', 'Takayasu Arteritis', 'Treatment Failure', 'Tumor Necrosis Factor-alpha', 'Young Adult'] | 21,416,236 | [['D06.472.040'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D03.132.225'], ['G07.690.773.984'], ['C16.320.382.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['D12.776.124.486.485.114.224.608', 'D12.776.124.790.651.114.224.537', 'D1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A case of prolonged hyperemesis resulting in hepatorenal failure, foetal distress and neonatal mortality. | Hyperemesis gravidarum is defined as a condition emerging during pregnancy, is prominent with severe nausea and vomiting, a water-electrolyte imbalance and liver-kidney function disorder and causes more than 5% loss of body weight. In cases of severe hyperemesis gravidarum, maternal morbidities such as water-electrolyt... | ['Alkalosis', 'Female', 'Fetal Distress', 'Fetal Growth Retardation', 'Hepatorenal Syndrome', 'Humans', 'Hyperemesis Gravidarum', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Perinatal Death', 'Pregnancy', 'Young Adult'] | 29,385,934 | [['C18.452.076.354'], ['C23.888.380'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['C06.552.465', 'C12.777.419.291', 'C13.351.968.419.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.407.500', 'C23.888.821.937.049.500'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['C13.703.572', 'C23.550... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Probing the 121-136 domain of lecithin:cholesterol acyltransferase using antibodies. | Lecithin:cholesterol acyltransferase (LCAT) catalyzes the esterification of plasma lipoprotein cholesterol in mammals as part of the reverse cholesterol transport pathway. Studies of the natural mutations of LCAT revealed a region that is highly sensitive to mutations (residues 121-136) and it is highly conserved in si... | ['Adsorption', 'Amino Acid Substitution', 'Animals', 'Antibodies', 'Blotting, Western', 'Catalysis', 'Cell Line', 'Cricetinae', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Humans', 'Mutation', 'Phosphatidylcholine-Sterol O-Acyltransferase', 'Precipitin Tests', 'Protein Structure, Tertiary', 'Recombinant Proteins'... | 11,368,007 | [['G01.030', 'G02.020'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G02.130'], ['A11.251.210'], ['B01.050.150.900.649.313.99... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cardiac massage in the early days of the technique. An instrument of dubious usefulness]. | Authors expose a short historical profile of heart massage techniques purposed and realized in the second part of the 19th and beginning of the 20th century. Some methods were well known and diffused, and object of discussion, as demonstrated by Macaura's Blood Circulator, an instrument used for external heart massage,... | ['England', 'Heart Massage', 'History, 19th Century', 'History, 20th Century'] | 7,017,464 | [['Z01.542.363.300'], ['E02.365.647.375', 'E04.100.376.458', 'E04.928.220.380'], ['K01.400.504.937'], ['K01.400.504.968']] | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Comparison of the viability and developmental characteristics of Echinococcus multilocularis isolates from human patients in France. | Alveolar echinococcosis, due to E. multilocularis, is usually a fatal disease in patients whether treated by benzimidazolecarbamates or not. However, aborted infections have been described, suggesting the existence of strains of parasites of varying pathogenicity. These observations led us to analyse the viability of l... | ['Adolescent', 'Adult', 'Aged', 'Animals', 'Echinococcosis, Hepatic', 'Echinococcus', 'Female', 'Gerbillinae', 'Humans', 'Larva', 'Liver', 'Male', 'Mice', 'Mice, Inbred AKR', 'Middle Aged'] | 2,312,231 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['B01.050.500.500.736.215.327'], ['B01.050.150.900.649.313.992.635.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A03.620'], ['B0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Friend virus-induced immunodepression: effect of neuraminidase treatment on Thy-1.2 antigen expression and cytotoxic potential of splenocytes from virus-infected mice. | Infection of susceptible strains of mice with Friend leukemia virus (FLV) results in a profound depression of cell-mediated immunity as assessed by lymphocyte-mediated cytotoxicity. This depression occurs early in the disease, before the onset of splenomegaly, and is associated with a decline in the susceptibility of s... | ['Animals', 'Antilymphocyte Serum', 'Complement System Proteins', 'Cytotoxicity Tests, Immunologic', 'Female', 'Friend murine leukemia virus', 'Immunosuppression', 'Leukemia, Experimental', 'Lymphocytes', 'Mice', 'Mice, Inbred Strains', 'Neuraminidase', 'Spleen', 'T-Lymphocytes'] | 305,416 | [['B01.050'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['D12.776.124.486.274'], ['E01.370.225.812.160', 'E05.200.812.160', 'E05.478.594.160', 'E05.940.245'], ['B04.613.807.375.525.225', 'B04.820.650.375.525.2... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estrogen upregulates endothelial nitric oxide synthase gene expression in fetal pulmonary artery endothelium. | NO, produced by endothelial NO synthase (eNOS), is a key mediator of pulmonary vasodilation during cardiopulmonary transition at birth. The capacity for NO production is maximal at term because pulmonary eNOS expression increases during late gestation. Since fetal estrogen levels rise markedly during late gestation and... | ['Animals', 'Cells, Cultured', 'Endothelium, Vascular', 'Estradiol', 'Estrogen Antagonists', 'Fetus', 'Fulvestrant', 'Gene Expression Regulation, Enzymologic', 'Immunohistochemistry', 'Nitric Oxide Synthase', 'Pulmonary Artery', 'RNA, Messenger', 'Receptors, Estrogen', 'Sheep', 'Transfection', 'Up-Regulation', 'Vasodil... | 9,285,637 | [['B01.050'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.347.295', 'D27.505.696.399.450.327'], ['A16.378'], ['D04.210.500.365.415.248.660', 'D06.472.334.851.437.500.500'], ['G05.308.320'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel approach for classifying protruding ears is easy to calculate and implement in daily clinical practice. | AIM: Protruding ears are a prevalent deformity, with a reported incidence of 5% in the paediatric population, but it lacks a simple digital classification. The aim of this study was to find a parameter that would objectively allow the photographic classification of protrusion, by comparing frontal facial images of pati... | ['Adolescent', 'Child', 'Child, Preschool', 'Ear Auricle', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Prospective Studies', 'Reference Values', 'Severity of Illness Index'] | 28,394,456 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['A09.246.272.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.978.810'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effect of aspirin on blood-lipid interaction and lipid peroxidation phenomena in relation to partition coefficient and biological activity. | Considering the lipophilicity of aspirin (log P = -1.15), a significant contributor to its action mechanism, interaction of the drug with the whole lipids of goat blood have been investigated using phospholipid binding and lipid peroxidation phenomena as the parameters under investigation. The lipid content change alon... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Aspirin', 'Fatty Acids', 'Goats', 'Lipid Peroxidation', 'Lipids', 'Phosphorus'] | 12,561,950 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389.657.410.595.176'], ['D10.251'], ['B01.050.150.900.649.313.500.380.513'], ['G02.111.515', 'G03.295.531.587'], ['D10'], ['D01.268.666']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lithospermic acid and ischemia/reperfusion injury of the rat small intestine prevention. | BACKGROUND: Intestinal ischemia and reperfusion (I-R) injury of different causes, including cardiac insufficiency, sepsis, vasodepressant and cardiodepressant drugs, and complications of long-lasting surgery, represents a major clinical problem.OBJECTIVES: The purpose of the present study was to investigate whether lit... | ['Animals', 'Benzofurans', 'Catalase', 'Depsides', 'Glutathione Peroxidase', 'Intestine, Small', 'Malondialdehyde', 'Peroxidase', 'Rats', 'Rats, Sprague-Dawley', 'Reperfusion Injury', 'Superoxide Dismutase'] | 23,240,448 | [['B01.050'], ['D03.633.100.127'], ['D08.811.682.732.332'], ['D02.241.223.100.300.100', 'D02.241.511.390.100', 'D02.455.426.559.389.127.281.100', 'D02.455.426.559.389.657.410.100'], ['D08.811.682.732.500'], ['A03.556.124.684'], ['D02.047.700'], ['D08.811.682.732.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Defining a recovery-oriented cascade of care for opioid use disorder: A community-driven, statewide cross-sectional assessment. | BACKGROUND: In light of the accelerating and rapidly evolving overdose crisis in the United States (US), new strategies are needed to address the epidemic and to efficiently engage and retain individuals in care for opioid use disorder (OUD). Moreover, there is an increasing need for novel approaches to using health da... | ['Analgesics, Opioid', 'Clinical Protocols', 'Cross-Sectional Studies', 'Drug Overdose', 'Humans', 'Naltrexone', 'Narcotic Antagonists', 'Opiate Substitution Treatment', 'Opioid-Related Disorders', 'Rhode Island', 'Risk Assessment', 'Risk Factors', 'Social Work', 'Stakeholder Participation', 'Substance-Related Disorder... | 31,743,335 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E02.183', 'N05.715.360.330.125'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development. | HeLa Tet-Off cells were transfected transiently as well as stably with a recombinant plasmid (pLuc/705) carrying the luciferase gene interrupted by a mutated human beta-globin intron 2 (IVS2-705). The mutation in the intron causes aberrant splicing of luciferase pre-mRNA, preventing translation of luciferase. However, ... | ['Alternative Splicing', 'Cell Line', 'Gene Expression Regulation, Enzymologic', 'HeLa Cells', 'Humans', 'Luciferases', 'Oligonucleotides, Antisense', 'Point Mutation', 'Protein Synthesis Inhibitors', 'RNA Precursors', 'Tetracycline', 'Transfection', 'Up-Regulation'] | 9,572,837 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['A11.251.210'], ['G05.308.320'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.517', 'D12.776.532.510'], ['D13.150.480', 'D13.444.600.150.640', 'D13.695.578.424.480', 'D27... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Image-Guided Lateral Mass Osteotomy for En Bloc Resection of Cervical Ewing Sarcoma: A Technical Note. | BACKGROUND: En bloc resection of Ewing sarcoma in the cervical spine according to Enneking's principles is technically challenging owing to the proximity of important neurovascular structures, the complex local anatomy, and the biomechanical instability of radical resection. The rarity of Ewing sarcoma and variability ... | ['Adult', 'Cervical Vertebrae', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Osteotomy', 'Positron-Emission Tomography', 'Sarcoma, Ewing', 'Spinal Neoplasms', 'Surgery, Computer-Assisted', 'Treatment Outcome'] | 28,532,919 | [['M01.060.116'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E04.555.580'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.825.800.399', 'E01.370.384.730.800.399'], ['C04.557.450.565.575.650.800', 'C04.557.450.... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Choice, Transparency, Coordination, and Quality Among Direct-to-Consumer Telemedicine Websites and Apps Treating Skin Disease. | IMPORTANCE: Evidence supports use of teleconsultation for improving patient access to dermatology. However, little is known about the quality of rapidly expanding direct-to-consumer (DTC) telemedicine websites and smartphone apps diagnosing and treating skin disease.OBJECTIVE: To assess the performance of DTC telederma... | ['Adult', 'Continuity of Patient Care', 'Contraindications', 'Data Collection', 'Dermatologists', 'Dermatology', 'Diagnostic Errors', 'Disclosure', 'Female', 'Guideline Adherence', 'Humans', 'Internet', 'Licensure, Medical', 'Male', 'Medical History Taking', 'Middle Aged', 'Mobile Applications', 'Patient Preference', '... | 27,180,232 | [['M01.060.116'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E02.208'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['M01.526.485.810.215', 'N02.360.810.215'], ['H02.403.225'], ['E01.354', 'N02.421.450.280'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Dise... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Methods for liquid filling inflated lungs and measuring any retained gas. | A method is described for liquid filling lungs without collapse by ventilating them on CO2 and then absorbing this gas with isotonic Tris buffer solution. The gas retained in each of 16 liquid-filled lungs has been measured by their compression in a dilatometer and averages 0.13% of lung volume. The liquid filling meth... | ['Absorption', 'Animals', 'Carbon Dioxide', 'Functional Residual Capacity', 'Gases', 'Lung', 'Pressure', 'Rabbits'] | 6,794,206 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E01.370.386.700.485.750.275', 'G09.772.850.390'], ['D01.362'], ['A04.411'], ['G01.374.715'], ['B01.050.150.900.649.313.968.700']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
â1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib. | INTRODUCTION: The overexpression of human epidermal growth factor receptor (HER)-2 in 20% of human breast cancers and its association with aggressive growth has led to widespread use of HER2-targeted therapies, such as trastuzumab (T) and lapatinib (L). Despite the success of these drugs, their efficacy is limited in p... | ['Antibodies', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cell Proliferation', 'Drug Resistance, Neoplasm', 'ErbB Receptors', 'Focal Adhesion Kinase 1', 'Humans', 'Integrin beta1', 'Lapatinib', 'Phosphorylation', 'Quinazolines', 'RNA, Small Interfering', 'Rece... | 21,884,573 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RNA processing enables predictable programming of gene expression. | Complex interactions among genetic components often result in variable systemic performance in designed multigene systems. Using the bacterial clustered regularly interspaced short palindromic repeat (CRISPR) pathway we develop a synthetic RNA-processing platform, and show that efficient and specific cleavage of precur... | ['Escherichia coli', 'Gene Expression', 'Genetic Engineering', 'Inverted Repeat Sequences', 'Operon', 'RNA Processing, Post-Transcriptional', 'Untranslated Regions'] | 22,983,090 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['E05.393.420'], ['G02.111.570.080.708.800.325', 'G05.360.080.708.800.325'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G02.111.760', 'G03.839', 'G05.308.700'], ['D13.444.735.544.875', 'D13.444.735.790.878', 'G05.360.340.024.220.880', 'G05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Where patients with cancer die in South Australia, 1990-1999: a population-based review. | OBJECTIVE: To determine the place of death of South Australians who die of cancer.DESIGN: A population-based, cross-sectional study of data from the South Australian Cancer Registry.PARTICIPANTS: 29,230 patients with cancer dying in 1990-1999.MAIN OUTCOME MEASURES: Place of death; patient demography; year of death; sur... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Cross-Sectional Studies', 'Female', 'Health Facilities', 'Home Nursing', 'Hospices', 'Hospitals, Rural', 'Hospitals, Urban', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Neoplasms', 'Nursing Homes', 'Socioeconomic Factors', 'South Australia', 'Statistics, N... | 11,795,541 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N02.278'], ['E02.760.611.470', 'N02.421.143.524.470', 'N02.421.533.320'], ['N02.278.421.556.185', 'N02.421.143.550'], ['N02.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Signal-detection, threshold, and dual-process models of recognition memory: ROCs and conscious recollection. | Threshold- and signal-detection-based models have dominated theorizing about recognition memory. Building upon these theoretical frameworks, we have argued for a dual-process model in which conscious recollection (a threshold process) and familiarity (a signal-detection process) contribute to memory performance. In the... | ['Adult', 'Awareness', 'Female', 'Humans', 'Male', 'Mental Recall', 'ROC Curve', 'Retention, Psychology', 'Semantics', 'Signal Detection, Psychological', 'Speech Perception', 'Verbal Learning'] | 9,063,609 | [['M01.060.116'], ['F02.463.188.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['F02.463.425.540.772'], ['L01.559.598.745'], ['E01.370.685.814', 'E05.796.908', 'F02.463.593.257.800', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication. | Nijmegen breakage syndrome (NBS) is characterized by genome instability and cancer predisposition. NBS patients contain a mutation in the NBS1 gene, which encodes the NBS1 component of the DNA double-strand break (DSB) response complex MRE11/RAD50/NBS1. To investigate the NBS phenotype in more detail, we combined the m... | ['Animals', 'Cell Cycle', 'Cell Cycle Proteins', 'Cells, Cultured', 'Chromosome Breakage', 'DNA', 'DNA Damage', 'DNA Helicases', 'DNA Replication', 'DNA-Binding Proteins', 'Female', 'Mice', 'Nijmegen Breakage Syndrome', 'Nuclear Proteins', 'Recombination, Genetic'] | 19,782,649 | [['B01.050'], ['G04.144'], ['D12.776.167'], ['A11.251'], ['C23.550.210.170', 'G05.200.210.170', 'G05.365.590.175.175'], ['D13.444.308'], ['G05.200'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['G02.111.225', 'G05.226'], ['D12.776.260'], ['B01.050.150.900.649.313.992.635.505.500'], ['C18.452.284.600'], ['D12.776.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Physico-chemical profiling of centrally acting molecules for prediction of pharmacokinetic properties]. | Physico-chemical profiling is a fundamental tool at the early stage of drug discovery in screening drug-like candidates. Complex physico-chemical profiling, including molecular properties such as solubility, ionization, lipophilicity and permeability, has been found to be of predictive power in ADME (absorption, distri... | ['Chemistry, Physical', 'Pharmaceutical Preparations', 'Pharmacokinetics', 'Piperazines', 'Piperidines', 'Potentiometry', 'Reproducibility of Results', 'Solubility'] | 18,986,088 | [['H01.181.529'], ['D26'], ['G03.787', 'G07.690.725'], ['D03.383.606'], ['D03.383.621'], ['E05.196.922.750', 'E05.301.710'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G02.805']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Recombinant human ciliary neurotrophic factor stimulates the metabolic activity of SH-SY5Y cells as measured by a cytosensor microphysiometer. | Information on the transmembrane signaling events and subsequent biochemical processes initiated by ciliary neurotrophic factor (CNTF) receptor activation in neurons is lacking. SH-SY5Y cells, a human neuroblastoma cell line expressing CNTF receptors, were used to study metabolic changes associated with functional liga... | ['Animals', 'Cell Line', 'Ciliary Neurotrophic Factor', 'Dose-Response Relationship, Drug', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Mice', 'Nerve Growth Factors', 'Nerve Tissue Proteins', 'Neuroblastoma', 'Phosphatidylinositol Diacylglycerol-Lyase', 'Phosphoinositide Phospholipase C', 'Phosphoric Diester H... | 8,069,684 | [['B01.050'], ['A11.251.210'], ['D12.644.276.860.212', 'D12.776.467.860.212', 'D12.776.631.600.212', 'D23.529.850.212'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.276.860', ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vaginal micronized progesterone in continuous hormone replacement therapy. A prospective randomized study. | BACKGROUND: In the non-hysterectomized post-menopausal woman undergoing estrogen replacement therapy, the co-administration of a progestogen is mandatory to counteract the estrogenic proliferative effect on the endometrium. Metabolic and tissue effects of the various progestins vary with dosage and route of administrat... | ['Administration, Intravaginal', 'Female', 'Hormone Replacement Therapy', 'Humans', 'Middle Aged', 'Progesterone', 'Prospective Studies'] | 12,432,337 | [['E02.319.267.120.500'], ['E02.319.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Freezing temperature of finger skin. | In 45 subjects, 154 frostnips of the finger were induced by cooling in air at -15 degrees C with various wind speeds. The mean supercooled skin temperature at which frostnip appeared was -9.4 degrees C. The mean skin temperature rise due to heat of fusion at ice crystallization was 5.3 degrees C. The skin temperature r... | ['Adult', 'Cold Temperature', 'Frostbite', 'Humans', 'Male', 'Middle Aged', 'Skin Temperature', 'Vasomotor System', 'Wind'] | 985,400 | [['M01.060.116'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['C26.212.500', 'C26.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.110.753', 'G13.750.844'], ['A08.800.050.800.900'], ['G16.500.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Study of the interaction of inorganic and organic compounds of cell culture medium with a Ti surface. | The interaction between Ti and each component of Dulbecco's modified Eagle's medium was studied in depth using different techniques, such as the measurement of the corrosion potential, electrochemical impedance spectroscopy and polarization curves. The characterization of metal surfaces was carried out by scanning elec... | ['Culture Media', 'Electrochemistry', 'Inorganic Chemicals', 'Microscopy, Electron, Scanning', 'Organic Chemicals', 'Spectrum Analysis', 'Titanium', 'X-Rays'] | 19,539,064 | [['D27.720.470.305', 'E07.206'], ['H01.181.529.307'], ['D01'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D02'], ['E05.196.867'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Inferior alveolar nerve regeneration and incisor pulpal reinnervation following intramandibular neurotomy in the cat. | Regeneration of the inferior alveolar nerve and mandibular incisor pulpal reinnervation was qualitatively and quantitatively examined by electron microscopy 2 days--11 months after intramandibular neurotomy in young adult cats. Fifteen millimeters central to the proximal stump moderate atrophic alterations of myelinate... | ['Animals', 'Axons', 'Cats', 'Denervation', 'Dental Pulp', 'Incisor', 'Mandibular Nerve', 'Microscopy, Electron', 'Nerve Degeneration', 'Nerve Fibers', 'Nerve Fibers, Myelinated', 'Nerve Regeneration'] | 7,116,174 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E04.525.210'], ['A14.549.167.900.260'], ['A14.549.167.860.425'], ['A08.800.800.120.760.500'], ['E01.370.350.515.402', 'E05.595.402'], ['C23.550.737'], ['A08.675.542', 'A11.671.501']... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rates and Reasons for Nonuse of Prescription Medication for Inflammatory Bowel Disease in a Referral Clinic. | BACKGROUND: We aimed to determine the rates and reasons for nonuse of inflammatory bowel disease (IBD)-specific medication in a referral clinic.METHODS: Consecutive persons with Crohn's disease (CD) (n = 423) and ulcerative colitis (UC) (n = 342) were followed in a single clinic over 2 years. At each patient visit, it ... | ['Adult', 'Colitis, Ulcerative', 'Crohn Disease', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Medication Adherence', 'Middle Aged', 'Prognosis', 'Referral and Consultation', 'Remission Induction', 'Treatment Refusal'] | 26,933,748 | [['M01.060.116'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.75... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Classical polyarteritis nodosa and microscopic polyarteritis with medium vessel involvement--a comparison of the clinical and laboratory features. | Microscopic polyarteritis may involve medium-sized and small blood vessels as well as arterioles, venules and capillaries. We have compared the clinical and laboratory features in patients with microscopic polyarteritis and medium vessel involvement, with the features found in patients with polyarteritis nodosa affecti... | ['Adult', 'Aged', 'Antibodies, Antineutrophil Cytoplasmic', 'Arteritis', 'Biomarkers', 'Biopsy', 'Female', 'Glomerulonephritis', 'Humans', 'Male', 'Middle Aged', 'Polyarteritis Nodosa', 'Prognosis'] | 9,105,764 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323.190', 'D12.776.124.790.651.114.323.190', 'D12.776.377.715.548.114.323.190', 'D23.101.050'], ['C14.907.940.090'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Finite element modelling of the glenohumeral capsule can help assess the tested region during a clinical exam. | The objective of this research was to examine the efficacy of evaluating the region of the glenohumeral capsule being tested by clinical exams for shoulder instability using finite element (FE) models of the glenohumeral joint. Specifically, the regions of high capsule strain produced by glenohumeral joint positions co... | ['Biomechanical Phenomena', 'Finite Element Analysis', 'Humans', 'Physical Examination', 'Shoulder Joint'] | 20,013,435 | [['G01.154.090', 'G01.374.089'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600'], ['A02.835.583.748']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolated tibial polyethylene insert exchange outcomes after total knee arthroplasty. | UNLABELLED: Total knee arthroplasty (TKA) using a modular design allows isolated tibial polyethylene insert exchange (ITPIE) as a treatment option for isolated polyethylene failure. We asked whether ITPIE in selected patients would provide high survivorship and identified factors predicting success or failure. We retro... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'Female', 'Health Status Indicators', 'Humans', 'Knee Joint', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Outcome Assessment, Health Care', 'Pain Measurement', 'Polyethylene', 'Prosthesis Design', 'Prosthesis Failure', 'Radiography'... | 19,672,671 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E07.695.400.410'], ['M01.060.116.630'], ['C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
IR-Met and IR-leu-enkephalin content in the perioesophageal ganglia of Helix aspersa seasonal variations. | 1. In order to determine the presence of opioid peptides and their possible variation throughout the year in the different ganglia of the perioesophageal ring of the terrestrial snail Helix aspersa, radioimmunoassays with highly specific antisera risen for Met-enkephalin (ME) and Leu-enkephalin (LE) were carried out mo... | ['Animals', 'Enkephalin, Leucine', 'Enkephalin, Methionine', 'Esophagus', 'Ganglia', 'Helix, Snails', 'Seasons'] | 1,687,560 | [['B01.050'], ['D12.644.400.575.281.231', 'D12.776.631.650.575.281.231'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['A03.556.875.500'], ['A08.340'], ['B01.050.500.644.400.750.450'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Large-scale separation of antipsychotic alkaloids from Rauwolfia tetraphylla L. by pH-zone-refining fast centrifugal partition chromatography. | pH-zone-refining centrifugal partition chromatography was successively applied in the large-scale separation of close R(f) antipsychotic indole alkaloids directly from CHCl(3) fraction of Rauwolfia tetraphylla leaves. Two experiments with increasing mass from 500 mg to 3 g of crude alkaloid extracts (1C) of R. tetrap... | ['Alkaloids', 'Antipsychotic Agents', 'Countercurrent Distribution', 'Hydrogen-Ion Concentration', 'Plant Extracts', 'Rauwolfia'] | 23,335,460 | [['D03.132'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.196.181.400.555', 'E05.196.278'], ['G02.300'], ['D20.215.784.500', 'D26.667'], ['B01.650.940.800.575.912.250.456.500.777']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different effect of ouabain on endothelin-1-induced extracellular signal-regulated kinase stimulation in rat heart and tail artery. | Endogenous ouabain may play a role in the control of cardiovascular system function. In this study, we investigated the effects of a long-term ouabain treatment on basal and endothelin-1 (ET-1)-induced phosphorylation of cardiac and vascular extracellular signal-regulated kinases 1 and 2 (ERK-1 and ERK-2), which are in... | ['Animals', 'Arteries', 'Coronary Vessels', 'Endothelin-1', 'Male', 'Mitogen-Activated Protein Kinases', 'Ouabain', 'Rats', 'Rats, Sprague-Dawley', 'Tail'] | 12,658,056 | [['B01.050'], ['A07.015.114'], ['A07.015.114.269', 'A07.015.908.194'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['D04.210.500.155.580.130.750.600', 'D09.408.180.810.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Supraventricular tachycardia in newborn infants and infants]. | Four types of supraventricular tachycardia were identified in a retrospective study of 71 babies who presented under the age of 3 months. The arrhythmia originated in the atrium in the first two types (25% of cases, atrial tachycardia 10 cases, chaotic atrial tachycardia 7 cases). In the other types the arrhythmia orig... | ['Arrhythmias, Cardiac', 'Atrioventricular Node', 'Electrocardiography', 'Female', 'Heart Atria', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Retrospective Studies', 'Tachycardia, Paroxysmal', 'Wolff-Parkinson-White Syndrome'] | 526,111 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The therapeutic effects of the free-associative state of consciousness. | Free association is therapeutically helpful in the regulation of states of consciousness. A person who free-associates enters a particular state of consciousness characterized by increased subjective self-awareness and disregard for reality, together with implicit pulls for objective self-awareness and reality adherenc... | ['Adult', 'Association', 'Consciousness', 'Female', 'Humans', 'Play and Playthings', 'Psychoanalytic Interpretation'] | 16,104,336 | [['M01.060.116'], ['F02.463.425.069', 'F04.754.720.346'], ['F02.463.188.409', 'F02.830.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.450.642.693'], ['F04.628']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Surface EMG shows distinct populations of muscle activity when measured during sustained sub-maximal exercise. | Muscle activity patterns were measured from the rectus femoris, biceps femoris, tibialis anterior and gastrocnemius medialis muscles using electromyography (EMG). Recordings were made from six runners while they ran for 30 mm around a track at a constant, self-selected pace. They were made from three sites along each m... | ['Adult', 'Electromyography', 'Exercise', 'Female', 'Humans', 'Male', 'Muscle Contraction', 'Muscle Fatigue', 'Muscle, Skeletal', 'Running'] | 11,820,321 | [['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494'], ['G11.427.550'], ['A02.633.567', 'A10.690.552.500'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Evidence for a defect in growth hormone-releasing factor signal transduction in the dwarf (dw/dw) rat pituitary. | Dwarf (dw/dw) rats exhibit a 40% reduction in body growth, isolated GH deficiency (less than 5% of normal pituitary content), and a decreased number of pituitary somatotrophs (15-20% of normal). Since GH-releasing factor (GRF) stimulates GH synthesis and secretion and somatotroph proliferation, and its effects are prob... | ['Alprostadil', 'Animals', 'Body Weight', 'Cells, Cultured', 'Cholera Toxin', 'Colforsin', 'Cyclic AMP', 'Dwarfism, Pituitary', 'Female', 'Growth Hormone', 'Growth Hormone-Releasing Hormone', 'Immunohistochemistry', 'Kinetics', 'Male', 'Pituitary Gland, Anterior', 'Rats', 'Rats, Mutant Strains', 'Signal Transduction', ... | 1,647,312 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A11.251'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['D02.455.849.291.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The anatomic relation among the nerve roots, intervertebral foramina, and intervertebral discs of the cervical spine. | STUDY DESIGN: An anatomic study of the cervical intervertebral foramina, nerve roots, and intradural rootlets performed using a surgical microscope.OBJECTIVES: To investigate the anatomy of cervical root compression, and to obtain the anatomic findings related to cervical foraminotomy for the treatment of cervical radi... | ['Aged', 'Aged, 80 and over', 'Cervical Vertebrae', 'Female', 'Humans', 'Intervertebral Disc', 'Male', 'Middle Aged', 'Radiculopathy', 'Spinal Nerve Roots'] | 10,703,098 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['M01.060.116.630'], ['C10.668.829.820'], ['A08.800.800.720.725']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. | The human DNA polymerase gamma catalytic subunit was overexpressed in recombinant baculovirus-infected insect cells, and the 136 000 Da protein was purified to homogeneity. Application of the same purification protocol to HeLa mitochondrial lysates permitted isolation of native DNA polymerase gamma as a single subunit,... | ['Amino Acid Sequence', 'Amino Acids', 'Catalysis', 'DNA Polymerase gamma', 'DNA-Directed DNA Polymerase', 'Deoxyribonucleotides', 'Escherichia coli', 'Exonucleases', 'Humans', 'Mutagenesis, Site-Directed', 'Peptide Fragments', 'Recombinant Proteins', 'Substrate Specificity'] | 9,671,525 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['G02.130'], ['D08.811.913.696.445.308.300.169', 'D12.776.575.280'], ['D08.811.913.696.445.308.300'], ['D13.695.201'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.352.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.420... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Host community structure and infestation by ixodid ticks: repeatability, dilution effect and ecological specialization. | Abundance of a species in a location results from the interplay between the intrinsic properties of that species and the extrinsic properties, both biotic and abiotic, of the local habitat. Intrinsic factors promote among-population stability in abundance, whereas extrinsic factors generate variation among populations ... | ['Animals', 'Ecosystem', 'Host-Parasite Interactions', 'Ixodidae', 'Mammals', 'Population Dynamics', 'Species Specificity'] | 17,684,769 | [['B01.050'], ['G16.500.275.157', 'N06.230.124'], ['G16.527.200.400'], ['B01.050.500.131.166.132.832.400'], ['B01.050.150.900.649'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G16.824']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Study of human epithelial cell detachment and damage: development of a model. | Detachment of epithelial structures from underlying basement membrane (BM) represents an important component of a number of human disease processes e.g. airway and alveolar diseases, gastrointestinal ulceration, and retinal diseases. This study describes a method of evaluating human epithelial cell detachment from BM t... | ['Amnion', 'Basement Membrane', 'Cell Count', 'Cells, Cultured', 'Collagen', 'Epithelial Attachment', 'Epithelial Cells', 'Epithelium', 'Extraembryonic Membranes', 'Fibronectins', 'Humans', 'Immunoenzyme Techniques', 'Laminin', 'Models, Biological', 'Periodontium', 'Spectrophotometry'] | 2,696,726 | [['A10.615.284.277', 'A16.254.750.277'], ['A10.272.220', 'A10.615.179'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A14.549.167.646.374'], ['A11.436'], ['A10.272'], ['A10.615.284', 'A16.254.750'], ['D12.776.377.715.390', 'D12.776.395.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statins use and female lung cancer risk in Taiwan. | In this present study, we found that the use of rosuvastatin with cumulative using duration >12 months could correlate with 2.8-fold increased risk of lung cancer in women. We did not have specific comments on these results. Further prospective clinical studies of statins use are needed to elucidate this issue. | ['Adult', 'Aged', 'Dyslipidemias', 'Female', 'Fluorobenzenes', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Logistic Models', 'Lung Neoplasms', 'Middle Aged', 'Pyrimidines', 'Risk Assessment', 'Risk Factors', 'Rosuvastatin Calcium', 'Sulfonamides', 'Taiwan', 'Time Factors'] | 23,272,648 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.584.500'], ['D02.455.426.559.389.358', 'D02.455.526.510.432'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450'... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The controllability beliefs scale used with carers of people with intellectual disabilities: psychometric properties. | BACKGROUND: Beliefs about the controllability of behaviour have been consistently shown to be important in understanding the responses of carers to the challenging behaviour of people with intellectual disabilities (IDs). This paper reports the reliability and validity of the controllability beliefs scale (CBS), a 15-i... | ['Adult', 'Attention Deficit and Disruptive Behavior Disorders', 'Attitude of Health Personnel', 'Caregivers', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Middle Aged', 'Power, Psychological', 'Psychometrics', 'Reproducibility of Results', 'Self-Injurious Behavior', 'Surveys and Questionnaires', 'Theory of ... | 22,471,440 | [['M01.060.116'], ['F03.625.094'], ['F01.100.050', 'N05.300.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['M01.060.116.630'], ['F01.658.780'], ['F04.711.780'], ['E05.318.370.725', 'E05.337... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tracing cytoplasmic Ca(2+) ion and water access points in the Ca(2+)-ATPase. | Sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) transports two Ca(2+) ions across the membrane of the sarco(endo)plasmic reticulum against the concentration gradient, harvesting the required energy by hydrolyzing one ATP molecule during each transport cycle. Although SERCA is one of the best structurally characteriz... | ['Binding Sites', 'Calcium', 'Cell Membrane', 'Cytoplasm', 'Molecular Dynamics Simulation', 'Protein Structure, Tertiary', 'Sarcoplasmic Reticulum Calcium-Transporting ATPases', 'Static Electricity', 'Water'] | 22,339,863 | [['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['A11.284.430.214'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709.610'], ['D08.811.277.040.025.314.250.500', 'D12.776.157.530.450.250.500.500', 'D12.776.157.530.813.250.500', 'D12.776.543.58... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Generative Anatomy Modeling Language (GAML). | BACKGROUND: This paper presents the Generative Anatomy Modeling Language (GAML) for generating variation of 3D virtual human anatomy in real-time. This framework provides a set of operators for modification of a reference base 3D anatomy. The perturbation of the 3D models is satisfied with nonlinear geometry constraint... | ['Computer Graphics', 'Computer Simulation', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Intubation, Intratracheal', 'Language', 'Male', 'Models, Anatomic', 'Nonlinear Dynamics', 'Programming Languages', 'Reference Values', 'Thyroid Gland', 'Trachea', 'User-Computer Interface'] | 28,260,232 | [['L01.224.108', 'L01.296.110'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['F01.145.209.399', 'L01.559'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['E05.599.850', 'H01.548.675'], ['L01.224.900.... | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Subdural hematoma caused by rupture of a posterior cerebral artery aneurysm. | Subdural hematoma (SDH) caused by rupture of a cerebral aneurysm is rare and is usually associated with delayed diagnosis and treatment. We present a patient of a posterior cerebral artery aneurysm presenting as subacute SDH. The incidence, mechanisms and treatment of this condition are discussed. | ['Aneurysm, Ruptured', 'Hematoma, Subdural', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 27,094,528 | [['C14.907.055.185'], ['C10.228.140.300.535.450.400', 'C10.900.300.837.600', 'C14.907.253.573.400.450', 'C23.550.414.838.700', 'C23.550.414.913.700', 'C26.915.300.490.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['M01.060.116.630'], ['E01... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Patterns of cough in the clinic. | Current guidelines for the management of cough highlight the value of a taking a careful history to establish specific features of the cough in particular its duration, typical triggers or aggravants and associated symptoms. Unfortunately the diagnostic yield from a history alone is poor and there is a need to understa... | ['Ambulatory Care', 'Animals', 'Biomedical Technology', 'Cough', 'Humans', 'Practice Guidelines as Topic'] | 21,296,676 | [['E02.760.106', 'N02.421.585.106'], ['B01.050'], ['J01.897.120.050'], ['C08.618.248', 'C23.888.852.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Factor VIII lacking the C2 domain retains cofactor activity in vitro. | Factor (F) VIII consists of a heavy chain (A1A2B domains) and light chain (A3C1C2 domains). The activated form of FVIII, FVIIIa, functions as a cofactor for FIXa in catalyzing the membrane-dependent activation of FX. Whereas the FVIII C2 domain is believed to anchor FVIIIa to the phospholipid surface, recent x-ray crys... | ['Blotting, Western', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Factor IXa', 'Factor VIII', 'Humans', 'Kinetics', 'Phospholipids', 'Protein Binding', 'Protein Structure, Tertiary', 'Thrombin'] | 20,529,839 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D08.811.277.656.300.760.310', 'D08.811.277.656.959.350.310'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of collision energy optimization on the measurement of peptides by selected reaction monitoring (SRM) mass spectrometry. | Proteomics experiments based on Selected Reaction Monitoring (SRM, also referred to as Multiple Reaction Monitoring or MRM) are being used to target large numbers of protein candidates in complex mixtures. At present, instrument parameters are often optimized for each peptide, a time and resource intensive process. Lar... | ['Mass Spectrometry', 'Peptides', 'Proteomics', 'Software'] | 21,090,646 | [['E05.196.566'], ['D12.644'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Bandages: indications for use and Drug Tariff status. | Community nurses need to have an up-to-date knowledge of which bandages are available on NHS prescription (i.e. on Drug Tariff) so that they can select the most appropriate bandage for their patient from those currently available. It seems that, for many years, both doctors and nurses have selected bandages for their p... | ['Bandages', 'Community Health Nursing', 'Humans', 'State Medicine', 'United Kingdom'] | 9,423,353 | [['E07.101'], ['H02.478.676.150', 'N02.421.143.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of high-dose intravenous dexamethasone on postlumbar discectomy pain. | STUDY DESIGN: A prospective, randomized triple-blind clinical trial.OBJECTIVE: To evaluate the effect of 40 and 80 mg intravenous (IV) dexamethasone versus placebo to reduce postlumbar diskectomy pain.SUMMARY OF BACKGROUND DATA: Lumbar discectomy is a procedure to ablate radicular and low pack pain (LBP) in select pati... | ['Adult', 'Dexamethasone', 'Diskectomy', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Humans', 'Injections, Intravenous', 'Intervertebral Disc Displacement', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Pain', 'Pain Measurement', 'Pain, Postoperative', 'Prospective Studies'] | 17,023,848 | [['M01.060.116'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['E02.718.444', 'E04.188.350', 'E04.555.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unrecognized trauma and PTSD among public mental health consumers with chronic and severe mental illness. | Lifetime prevalence of traumatic events and current PTSD was assessed among 142 mental health consumers with serious mental illness served by a psychosocial rehabilitation day program. Lifetime exposure to trauma was high (87%). The rate of PTSD based on the PTSD Checklist (PCL) was also high (19-30% depending on diffe... | ['Adult', 'Chronic Disease', 'Community Mental Health Centers', 'Female', 'Humans', 'Male', 'Medical Audit', 'Mental Disorders', 'Middle Aged', 'Severity of Illness Index', 'Stress Disorders, Post-Traumatic', 'United States', 'Wounds and Injuries'] | 16,868,841 | [['M01.060.116'], ['C23.550.291.500'], ['N02.278.035.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.700.175.500'], ['F03'], ['M01.060.116.630'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['F03.950.750.500'], [... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Accuracy of Physical Function Questions to Predict Moderate-Vigorous Physical Activity as Measured by Hip Accelerometry. | BACKGROUND: Functional capacity assessment is a core component of current perioperative cardiovascular evaluation and management guidelines for noncardiac surgery. The authors investigated the ability of standardized physical function questions to predict whether participants engaged in moderate physical activity as me... | ['Accelerometry', 'Adult', 'Aged', 'Aged, 80 and over', 'Exercise', 'Female', 'Forecasting', 'Hip Joint', 'Humans', 'Male', 'Middle Aged', 'Nutrition Surveys', 'Surveys and Questionnaires', 'Walking'] | 31,490,293 | [['E05.003'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G11.427.410.698.277', 'I03.350'], ['I01.320'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.980.485', 'N05.715.360.300.800.469', 'N06.850.505.616', 'N06.850.520.308.980.469'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. | BACKGROUND: Androgenetic alopecia (AGA) is characterized by the structural miniaturization of androgen-sensitive hair follicles in susceptible individuals and is anatomically defined within a given pattern of the scalp. Biochemically, one contributing factor of this disorder is the conversion of testosterone (T) to dih... | ['Adult', 'Alopecia', 'Cholestenone 5 alpha-Reductase', 'Double-Blind Method', 'Enzyme Inhibitors', 'Humans', 'Male', 'Middle Aged', 'Oxidoreductases', 'Phytotherapy', 'Pilot Projects', 'Plant Extracts', 'Serenoa', 'Sitosterols', 'Treatment Outcome'] | 12,006,122 | [['M01.060.116'], ['C17.800.329.937.122', 'C23.300.035'], ['D08.811.682.660.200'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D08.811.682'], ['E02.190.755'], ['E05.318.372.750', 'E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of Aerobic Training on Cognition and Brain Glucose Metabolism in Subjects with Mild Cognitive Impairment. | BACKGROUND: Aerobic training (AT) is a promising intervention for mild cognitive impairment (MCI).OBJECTIVE: To evaluate the effects of AT on cognition and regional brain glucose metabolism (rBGM) in MCI patients.METHODS: Subjects performed a twice-a-week, moderate intensity, AT program for 24 weeks. Assessment with AD... | ['Aged', 'Brain', 'Cognitive Dysfunction', 'Exercise', 'Exercise Therapy', 'Female', 'Fluorodeoxyglucose F18', 'Glucose', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Mental Status Schedule', 'Middle Aged', 'Neuropsychological Tests', 'Oxygen Consumption', 'Positron-Emission T... | 25,835,427 | [['M01.060.116.100'], ['A08.186.211'], ['F03.615.250.700'], ['G11.427.410.698.277', 'I03.350'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['D09.254.229.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['F04.711.513.603.500', ... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Short Term Fate of Great Saphenous Vein after Radiofrequency Ablation for Varicose Veins. | Background Radiofrequency ablation of varicose vein have gained popularity compared to conventional surgery due to comparable long term results in addition to definite immediate superiorities. This modality has been started in Nepal since August 2003 and the study on short term fate of ablated vein segment confirms the... | ['Adult', 'Catheter Ablation', 'Female', 'Femoral Vein', 'Humans', 'Male', 'Middle Aged', 'Nepal', 'Saphenous Vein', 'Thigh', 'Time Factors', 'Treatment Outcome', 'Ultrasonography, Doppler', 'Varicose Veins'] | 27,180,370 | [['M01.060.116'], ['E02.808.750.500', 'E04.014.760.500'], ['A07.015.908.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.252.245.674'], ['A07.015.908.819'], ['A01.378.610.750'], ['G01.910.857'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E01.370.350.850.850'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Transesophageal echocardiographic monitoring of critical left ventricular outflow tract obstruction following mitral xenograft replacement--a case report. | Left ventricular outflow tract obstruction (LVOTO) is a critical complication after mitral bioprosthesis. Intraoperative transesophageal echocardiographic (TEE) monitoring enables early diagnosis and guides prompt subsequent treatment. Here we report a case of mitral heart disease who developed critical LVOTO following... | ['Animals', 'Bioprosthesis', 'Echocardiography, Transesophageal', 'Female', 'Heart Valve Prosthesis', 'Humans', 'Middle Aged', 'Mitral Valve', 'Ventricular Outflow Obstruction'] | 12,194,395 | [['B01.050'], ['E07.695.100'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.507'], ['C14.280.955']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Two CGTCA motifs and a GHF1/Pit1 binding site mediate cAMP-dependent protein kinase A regulation of human growth hormone gene expression in rat anterior pituitary GC cells. | We established the cis-acting elements which mediate cAMP responsiveness of the human growth hormone (hGH) gene in transiently transfected rat anterior pituitary tumor GC cells. Analysis of the intact hGH gene or hGH 5'-flanking DNA (5'-FR) coupled to the hGh cDNA or chloramphenicol acetyltransferase or luciferase gene... | ['Animals', 'Base Sequence', 'Binding Sites', 'Cell Line', 'Cell Nucleus', 'Colforsin', 'Cyclic AMP', 'Cyclic AMP Response Element-Binding Protein', 'Cyclic AMP-Dependent Protein Kinases', 'DNA Primers', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Growth Hormone', 'HeLa Cells', 'Humans', 'Immunoblotting', 'M... | 8,294,429 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.776.260.108.184', 'D12.776.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The endo-beta-1,3-glucanase eng1p is required for dissolution of the primary septum during cell separation in Schizosaccharomyces pombe. | Schizosaccharomyces pombe cells divide by medial fission throughout contraction of an actomyosin ring and deposition of a multilayered division septum that must be cleaved to release the two daughter cells. Although many studies have focused on the actomoysin ring and septum assembly, little information is available co... | ['Base Sequence', 'Cell Division', 'DNA, Fungal', 'DNA-Binding Proteins', 'Gene Deletion', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Fungal', 'Genes, Fungal', 'Glucan Endo-1,3-beta-D-Glucosidase', 'Microscopy, Electron', 'Molecular Sequence Data... | 12,665,550 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D13.444.308.300'], ['D12.776.260'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308.310'], ['G05.308.320'], ['G05.308.330'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies. | AIMS: The insulin receptor substrate-1 (IRS-1) gene is among the most frequently studied candidate genes for Type 2 diabetes, but findings have been inconsistent. This may have been due to generally small study sizes, or to interaction with body fatness as suggested by studies of insulin sensitivity. The aim of this st... | ['Amino Acid Substitution', 'Anthropometry', 'Blood Glucose', 'Body Mass Index', 'Case-Control Studies', 'Diabetes Mellitus', 'Diabetes Mellitus, Type 2', 'Female', 'Genetic Predisposition to Disease', 'Glucose Intolerance', 'Humans', 'Insulin Receptor Substrate Proteins', 'Male', 'Middle Aged', 'Obesity', 'Odds Ratio'... | 15,209,769 | [['E05.393.420.601.035', 'G05.558.109'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750', 'C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of the effect of Block Level Awareness Campaign on performance indicators of National Leprosy Elimination Program in Vadodara district, Gujarat, India. | BACKGROUND: Leprosy is probably the oldest disease afflicting mankind and a public health problem for centuries. Many cases are hidden or undiagnosed, especially due to social stigma, and neglect of painless patches. Between years 2001 and 2005, during which time active surveillance for detection of leprosy was in prac... | ['Adolescent', 'Adult', 'Awareness', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Health Surveys', 'Humans', 'India', 'Leprosy', 'Male', 'National Health Programs', 'Rural Population', 'Urban Population', 'Young Adult'] | 25,851,761 | [['M01.060.057'], ['M01.060.116'], ['F02.463.188.150'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[What is the potential number of indications for liver grafts in France per year?]. | The progress recently made in liver transplantation requires an estimation of the potential number of cases per year in France. The study of French Death Rate per age group, compared with either formal, discutable or aleatory indications of transplantation, is a valuable basis for that calculation. It confirms the rela... | ['Adult', 'Child', 'Evaluation Studies as Topic', 'France', 'Humans', 'Liver Diseases', 'Liver Transplantation', 'Statistics as Topic'] | 3,542,687 | [['M01.060.116'], ['M01.060.406'], ['E05.337', 'N05.715.360.335'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Global proficiency study of human papillomavirus genotyping. | Internationally comparable quality assurance of Human Papillomavirus (HPV) DNA detection and typing methods is essential for evaluation of HPV vaccines and effective monitoring and implementation of HPV vaccination programs. Therefore, the World Health Organization (WHO) HPV Laboratory Network (LabNet) designed an inte... | ['Clinical Laboratory Techniques', 'DNA, Viral', 'Genotype', 'Papillomaviridae', 'Papillomavirus Infections', 'Quality Assurance, Health Care', 'Sensitivity and Specificity', 'Virology', 'World Health Organization'] | 20,844,222 | [['E01.370.225', 'E05.200'], ['D13.444.308.568'], ['G05.380'], ['B04.280.210.655', 'B04.613.204.655'], ['C01.925.256.650', 'C01.925.928.725'], ['N04.761.700', 'N05.700'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['H01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Use of animal-operated folding perches by rhesus macaques (Macaca mulatta). | Providing captive or laboratory animals with the best possible living conditions has led to many ideas about how caging environments can be enhanced and the animals' lives can be enriched. This study focused primarily on 2 issues: more efficient use of existing caging and providing animals with a measure of control ove... | ['Animals', 'Animals, Laboratory', 'Behavior, Animal', 'Environment, Controlled', 'Female', 'Housing, Animal', 'Learning', 'Macaca mulatta', 'Male', 'Social Behavior', 'Time Factors'] | 17,994,671 | [['B01.050'], ['B01.050.050.199'], ['F01.145.113'], ['N06.230.150'], ['J03.340.250', 'N06.230.150.360.250'], ['F02.463.425', 'F02.784.629.529'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['F01.145.813'], ['G01.910.857']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses. | PURPOSE: Balanced steady-state free precession (bSSFP) sequences can provide superior signal-to-noise ratio efficiency for hyperpolarized (HP) carbon-13 (13 C) magnetic resonance imaging by efficiently utilizing the nonrecoverable magnetization, but managing their spectral response is challenging in the context of meta... | ['Animals', 'Artifacts', 'Carbon Isotopes', 'Computer Simulation', 'Imaging, Three-Dimensional', 'Lactates', 'Magnetic Resonance Imaging', 'Mice', 'Phantoms, Imaging', 'Pyruvic Acid'] | 27,770,458 | [['B01.050'], ['E05.047'], ['D01.268.150.075', 'D01.496.123'], ['L01.224.160'], ['E01.370.350.400', 'L01.224.308.410'], ['D02.241.511.459'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E07.671'], ['D02.241.755.812.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sex chromosomes and the brain: a study of neuroanatomy in XYY syndrome. | AIM: To assess global and regional brain matter variations associated with XYY syndrome by comparison with Klinefelter syndrome and typical development.METHODS: We used two conceptually distinct voxel-based magnetic resonance imaging methods to examine brain structure in young males with XYY syndrome: (1) volumetric co... | ['Brain', 'Child', 'Child Development Disorders, Pervasive', 'Chromosomes, Human, X', 'Chromosomes, Human, Y', 'Frontal Lobe', 'Humans', 'Klinefelter Syndrome', 'Magnetic Resonance Imaging', 'Male', 'Neuropsychological Tests', 'Sex Chromosome Disorders', 'Temporal Lobe', 'XYY Karyotype'] | 23,057,627 | [['A08.186.211'], ['M01.060.406'], ['F03.625.164'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['A08.186.211.200.885.287.500.27... | ['Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Coordination chemistry of conformation-flexible 1,2,3,4,5,6-cyclohexanehexacarboxylate: trapping various conformations in metal-organic frameworks. | To study the conformations of 1,2,3,4,5,6-cyclohexanehexacarboxylic acid (H(6)L), eleven new coordination polymers have been isolated from hydrothermal reactions of different metal salts with 1e,2a,3e,4a,5e,6a-cyclohexanehexacarboxylic acid (3e+3a, H(6)L(I)) and characterized. They are [Cd(12)(mu(6)-L(II))(mu(10)-L(II)... | ['Cyclohexanes', 'Ligands', 'Metals', 'Models, Molecular', 'Molecular Conformation'] | 18,618,562 | [['D02.455.426.392.368.367'], ['D27.720.470.480'], ['D01.552'], ['E05.599.595'], ['G02.111.570.820']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantifiable hearing and no ABR: paradox or error? | Reports concerning the inability to record at least wave V of the ABR in patients with quantifiable hearing have generally been confined to patients with demonstrable neurological diseases. Four patients with no neurological evidence of brainstem dysfunction in whom the ABR's were either absent or showed thresholds ina... | ['Adult', 'Audiometry', 'Audiometry, Evoked Response', 'Child', 'Child, Preschool', 'Evoked Potentials, Auditory', 'False Positive Reactions', 'Female', 'Humans', 'Male', 'Vestibulocochlear Nerve Diseases'] | 7,429,038 | [['M01.060.116'], ['E01.370.382.375.060'], ['E01.370.382.375.060.050'], ['M01.060.406'], ['M01.060.406.448'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.807.800', 'C10.292.910']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Breast cancer risk factors in women participating in a breast screening program: a study on 11,850 Iranian females. | The incidence rate of breast cancer in developed countries is almost three-fold higher than in developing countries. Iran has had one of the lowest incidence rates for breast cancer in the world, but during the recent decades a marked increase has been seen. The purpose of this study was to investigate some established... | ['Adult', 'Aged', 'Anthropometry', 'Breast Neoplasms', 'Case-Control Studies', 'Early Detection of Cancer', 'Female', 'Follow-Up Studies', 'Humans', 'Iran', 'Logistic Models', 'Middle Aged', 'Pregnancy', 'Prognosis', 'Reproductive History', 'Risk Factors'] | 25,339,054 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.390.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Joint inference and alignment of genome structures enables characterization of compartment-independent reorganization across cell types. | BACKGROUND: Comparisons of Hi-C data sets between cell types and conditions have revealed differences in topologically associated domains (TADs) and A/B compartmentalization, which are correlated with differences in gene regulation. However, previous comparisons have focused on known forms of 3D organization while pote... | ['Algorithms', 'Cell Line', 'Chromosome Structures', 'Cluster Analysis', 'Computational Biology', 'Databases, Genetic', 'Enhancer Elements, Genetic', 'Genetic Loci', 'Genome, Fungal', 'Genome, Human', 'Histone Code', 'Humans', 'Polycomb-Group Proteins', 'Saccharomyces'] | 31,594,535 | [['G17.035', 'L01.224.050'], ['A11.251.210'], ['A11.284.430.106.279.345.190.160', 'G05.360.160'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Management of radiation maculopathy. | Radiation maculopathy is a delayed onset complication of radiation exposure. Various host and radiation parameters determine the risk of developing radiation maculopathy, which may be progressive. Total radiation dose delivered to the macula is the most important modifiable factor. Radiation maculopathy is not a singul... | ['Angiogenesis Inhibitors', 'Brachytherapy', 'Choroid Neoplasms', 'Fluorescein Angiography', 'Humans', 'Incidence', 'Iodine Radioisotopes', 'Laser Coagulation', 'Melanoma', 'Photochemotherapy', 'Radiation Dosage', 'Radiation Injuries', 'Retina', 'Retinal Neovascularization', 'Risk Factors', 'Tomography, Optical Coheren... | 22,907,147 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['E02.815.150'], ['C04.588.364.978.223', 'C11.319.494.198', 'C11.941.160.238', 'C11.941.855.198'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The metabolism of benzo(a)pyrene by the lungs of asbestos exposed rats. | A group of Fischer F344 rats were exposed to an aerosol of crocidolite asbestos for 36 d. Short-term organ cultures were established from the lungs of these animals and from a similar control group. The ability of these cultures to metabolise benzo(a)pyrene to water-soluble and ether-soluble forms was measured. Crocido... | ['Animals', 'Asbestos', 'Benzo(a)pyrene', 'In Vitro Techniques', 'Inactivation, Metabolic', 'Lung', 'Lung Neoplasms', 'Male', 'Rats', 'Rats, Inbred F344'] | 6,542,527 | [['B01.050'], ['D01.578.725.050', 'D01.837.725.700.760.070'], ['D02.455.426.559.847.799.306.300', 'D04.615.799.306.300'], ['E05.481'], ['G03.171.450', 'G03.787.225.450', 'G07.690.725.225.450'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of putative DNA repair inhibitors on DNA adduct levels and unscheduled DNA synthesis in rat hepatocytes exposed to 2-acetylaminofluorene. | The enzymology of DNA repair is currently under active investigation. The purpose of the present study was to examine the involvement of a number of enzymes (DNA polymerase alpha and beta, DNA topoisomerase II and ribonucleotide reductase) in the repair of chemically induced DNA damage in a mammalian cell system. This ... | ['2-Acetylaminofluorene', 'Animals', 'Aphidicolin', 'Cells, Cultured', 'Cytarabine', 'DNA Damage', 'DNA Repair', 'Dideoxynucleosides', 'Diterpenes', 'Hydroxyurea', 'In Vitro Techniques', 'Liver', 'Male', 'Nalidixic Acid', 'Nucleic Acid Synthesis Inhibitors', 'Rats', 'Topoisomerase I Inhibitors'] | 2,537,461 | [['D02.065.064.150', 'D02.241.081.018.110.080', 'D02.455.426.559.847.389.050', 'D04.615.389.050'], ['B01.050'], ['D02.455.849.291.075'], ['A11.251'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['G05.200'], ['G02.111.222', 'G05.219'], ['D13.570.230.500'], ['D02.455.849.291'], ['D02.065.950.39... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigating the recheck rules for urine analysis in children. | The aim of this study was to establish recheck rules of urinalysis in children by investigating the concordance rate of the results obtained using the LabUMat urine dry chemistry analyzer (referred to as dry chemistry) and the UriSed tangible composition analyzer with that of the microscopic examination. First, 1040 ur... | ['Adolescent', 'Cell Count', 'Child', 'Child, Preschool', 'Erythrocytes', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Kidney Diseases', 'Leukocytes', 'Male', 'Microscopy', 'Occult Blood', 'Urinalysis'] | 27,173,232 | [['M01.060.057'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['M01.060.406'], ['M01.060.406.448'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C12.777.419', 'C13.351.968.419'], ['A11.118.637', 'A15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Altered postreceptor signal transduction of formyl-Met-Leu-Phe receptors in polymorphonuclear leukocytes of patients with non-insulin-dependent diabetes mellitus. | The signal transduction of the formyl-Met-Leu-Phe (FMLP) receptor in polymorphonuclear leukocytes (PMNLs) from patients with non-insulin-dependent diabetes mellitus (NIDDM) was compared to that of PMNLs obtained from healthy volunteers. According to our previous studies in this group of patients neither the decrease in... | ['Arachidonic Acid', 'Calcium', 'Cell Membrane', 'Cells, Cultured', 'Diabetes Mellitus, Type 2', 'Enzyme Activation', 'Humans', 'Inositol Phosphates', 'Insulin', 'Male', 'Middle Aged', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Pertussis Toxin', 'Protein Kinase C', 'Receptor, Insulin', 'Receptors, Formy... | 9,434,801 | [['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['A11.251'], ['C18.452.394.750.149', 'C19.246.300'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.519.400', 'D09.853.519.400', 'D09.894.480'], ['... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Overexpression of the rice Osmyb4 gene increases chilling and freezing tolerance of Arabidopsis thaliana plants. | The expression of the gene Osmyb4, detected at low level in rice (Oryza sativa) coleoptiles grown for 3 days at 29 degrees C, is strongly induced by treatments at 4 degrees C. At sublethal temperatures of 10 and 15 degrees C, its expression in rice seedlings is already evident, but this effect cannot be vicariated by o... | ['Acclimatization', 'Arabidopsis', 'Base Sequence', 'Cold Temperature', 'Gene Expression Regulation, Plant', 'Molecular Sequence Data', 'Oryza', 'Plant Proteins', 'Plants, Genetically Modified', 'Promoter Regions, Genetic', 'Sequence Homology, Nucleic Acid', 'Transcription Factors'] | 14,675,437 | [['G07.025.133', 'G16.012.500.133'], ['B01.650.940.800.575.912.250.157.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G05.308.375'], ['L01.453.245.667'], ['B01.65... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Dopaminergic influence on rat tongue function and limb movement initiation. | Altering dopamine synaptic transmission can affect both cranial and limb sensorimotor function, but often to a different degree of severity. We hypothesized that haloperidol has dose-dependent but differential effects on lingual forces, lingual movement rates, and limb movement initiation. We measured average and maxim... | ['Analysis of Variance', 'Animals', 'Dopamine', 'Dopamine Antagonists', 'Dose-Response Relationship, Drug', 'Extremities', 'Haloperidol', 'Male', 'Motor Activity', 'Muscle Strength', 'Rats', 'Rats, Inbred F344', 'Tongue'] | 19,247,644 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['G07.690.773.875', 'G07.690.936.500'], ['A01.378'], ['D02.522.352.506'], ['F01.145.632', 'G11.427.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Extremely Low Frequency Electromagnetic Field in Mesenchymal Stem Cells Gene Regulation: Chondrogenic Markers Evaluation. | There is little evidence demonstrating the effects of electromagnetic fields (EMFs) generated within the biological entity and the effect of extrinsic fields on cellular programing. Taking the path of the more studied stimuli into attention, mechanical forces, it could be understood that nonchemical factors play a cons... | ['Alginates', 'Animals', 'Cells, Cultured', 'Chondrogenesis', 'Electromagnetic Fields', 'Gene Expression Regulation', 'Glucuronic Acid', 'Hexuronic Acids', 'Mesenchymal Stem Cells', 'Rabbits', 'SOX9 Transcription Factor', 'Tissue Scaffolds'] | 27,086,585 | [['D09.698.068'], ['B01.050'], ['A11.251'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['G01.358.500.260', 'G01.358.750.500'], ['G05.308'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptional regulation of the leukocyte adherence protein beta subunit during human myeloid cell differentiation. | Adherence reactions involving human leukocytes are mediated by a family of glycoprotein surface antigens composed of three different alpha subunits designated alpha L, alpha M, and alpha X, each of which is associated with a single beta subunit in an alpha 1 beta 1 heterodimer structure. We cloned the cDNA for the comm... | ['CD18 Antigens', 'Cell Adhesion', 'Cell Differentiation', 'Cloning, Molecular', 'DNA', 'Dimethylformamide', 'Gene Expression Regulation', 'Granulocytes', 'Humans', 'Leukemia, Myeloid', 'Macromolecular Substances', 'Membrane Glycoproteins', 'Nucleic Acid Hybridization', 'RNA, Messenger', 'Tetradecanoylphorbol Acetate',... | 2,901,419 | [['D12.776.395.550.200.275.750', 'D12.776.543.550.200.275.750', 'D12.776.543.750.705.408.200.249', 'D12.776.543.750.705.408.600.100.750', 'D12.776.543.750.705.833.249.750', 'D23.050.301.264.894.118', 'D23.050.301.350.275.750', 'D23.101.100.894.118'], ['G04.022'], ['G04.152'], ['E05.393.220'], ['D13.444.308'], ['D02.065... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome. | Rett syndrome (RTT) results from loss-of-function mutations in the gene encoding the methyl-CpG-binding protein 2 (MeCP2) and is characterized by abnormal motor, respiratory and autonomic control, cognitive impairment, autistic-like behaviors and increased risk of seizures. RTT patients and Mecp2-null mice exhibit redu... | ['Animals', 'Benzamides', 'Disease Models, Animal', 'Drug Partial Agonism', 'Female', 'Male', 'Methyl-CpG-Binding Protein 2', 'Mice', 'Mice, 129 Strain', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mice, Transgenic', 'Phosphorylation', 'Receptor, trkB', 'Respiratory Mechanics', 'Rett Syndrome'] | 22,302,819 | [['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.968.154.500'], ['D12.776.260.536', 'D12.776.660.235.550', 'D12.776.664.235.700'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.400.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improving treatment for obese women with early stage cancer of the uterus: rationale and design of the levonorgestrel intrauterine device ± metformin ± weight loss in endometrial cancer (feMME) trial. | PURPOSE: Endometrial adenocarcinoma (EC) is the most common gynaecologic cancer. Up to 90% of EC patients are obese which poses a health threat to patients post-treatment. Standard treatment for EC includes hysterectomy, although this has significant side effects for obese women at high risk of surgical complications a... | ['Adenocarcinoma', 'Biomarkers, Tumor', 'Diet', 'Endometrial Neoplasms', 'Exercise', 'Female', 'Humans', 'Intrauterine Devices', 'Levonorgestrel', 'Metformin', 'Neoplasm Staging', 'Obesity', 'Prospective Studies', 'Research Design', 'Weight Loss'] | 24,999,075 | [['C04.557.470.200.025'], ['D23.101.140'], ['G07.203.650.240'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.190.250.510'], ['D04.210.500.668.651.693.762.450'], ['D02.078.370.141.450'], ['E01... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
A general probabilistic model for group independent component analysis and its estimation methods. | Independent component analysis (ICA) has become an important tool for analyzing data from functional magnetic resonance imaging (fMRI) studies. ICA has been successfully applied to single-subject fMRI data. The extension of ICA to group inferences in neuroimaging studies, however, is challenging due to the unavailabili... | ['Brain', 'Brain Mapping', 'Computer Simulation', 'Data Interpretation, Statistical', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Models, Neurological', 'Models, Statistical', 'Principal Component Analysis'] | 21,517,789 | [['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Assessment of Health-Related Quality of Life between People with Parkinson's Disease and Non-Parkinson's: Using Data Drawn from the '100 for Parkinson's' Smartphone-Based Prospective Study. | Background: This study aims to assess the specific difference of the health-related quality of life between people with Parkinson's and non-Parkinson's. Methods: A total of 1710 people were drawn from a prospective study with a smartphone-based survey named '100 for Parkinson's' to assess health-related quality of life... | ['Aged', 'Case-Control Studies', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Parkinson Disease', 'Prospective Studies', 'Quality of Life', 'Smartphone', 'Surveys and Questionnaires'] | 30,428,518 | [['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Human erythrocyte acetylcholinesterase bears the Yta blood group antigen and is reduced or absent in the Yt(a-b-) phenotype. | The Cartwright (Yt) blood group antigens have previously been shown likely to reside on a phosphatidylinositol-linked erythrocyte membrane protein. In this study, an unusual individual whose red blood cells (RBCs) were of the previously unreported Yt(a-b-) phenotype were used, along with normal Yt(a+) cells, to investi... | ['Acetylcholinesterase', 'Antibodies, Monoclonal', 'Blood Group Antigens', 'Erythrocytes', 'Humans', 'Molecular Weight', 'Phenotype', 'Radioimmunoassay'] | 8,427,972 | [['D08.811.277.352.100.170.176'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.290', 'D23.050.705.230'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.494'], ['G05.695'], ['E01.370.384.700', 'E05.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of macrophage phagocytic activity by group A streptococcal cell walls. | Group A streptococcal cell walls inhibited phagocytosis of polystyrene latex particles by rat peritoneal macrophages in vitro. This inhibition was not accompanied by a measurable loss of cell viability. Group D streptococcal cell walls were relatively ineffective in altering phagocytosis. The effectiveness of group A v... | ['Animals', 'Cell Survival', 'Cell Wall', 'Latex', 'Macrophages', 'Microspheres', 'Peptidoglycan', 'Phagocytosis', 'Rats', 'Streptococcus pyogenes', 'Time Factors'] | 352,930 | [['B01.050'], ['G04.346'], ['A11.284.183'], ['D05.750.078.625', 'D20.215.721.124', 'D25.720.099.625', 'D25.720.099.750.500', 'D25.720.327.840.239', 'J01.637.051.720.099.625', 'J01.637.051.720.540'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['E07.565'], ['D09.400.420.700', 'D0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The clinical features of late onset acne compared with early onset acne in women. | BACKGROUND: Little is known about the clinical characteristics of acne based on the age of onset.OBJECTIVES: The aim of this study was to investigate the clinical characteristics of patients according to the age of onset of acne and evaluate whether the findings were related to regional differences in the density of Pr... | ['Acne Vulgaris', 'Adolescent', 'Adult', 'Age of Onset', 'Child', 'Female', 'Humans', 'Middle Aged', 'Sebum'] | 20,659,307 | [['C17.800.030.150', 'C17.800.794.111'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A12.200.702']] | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Do levels of perceived stress increase with increasing age after age 65? A population-based study. | BACKGROUND: psychological and health-related stressors often occur in advanced ages, but little is known about perceived stress in adults aged 65 and over. This study aimed to test the hypothesis that levels of perceived stress increase with increasing age and to detect factors that may account for the association.METH... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Chi-Square Distribution', 'Female', 'Health Status', 'Humans', 'Linear Models', 'Male', 'Multivariate Analysis', 'Perception', 'Prevalence', 'Risk Factors', 'Sex Factors', 'Stress, Psychological', 'Surveys and Questionnaires', 'Sweden'] | 26,187,986 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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