Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[Multiple Endocrine Neoplasia]. | Multiple endocrine neoplasia(MEN)is an autosomal dominantly inherited tumor syndrome which develop tumors in multiple endocrine organs and its subtype, MEN1 and MEN2, are well known. The causative gene for MEN1 is the MEN1 gene located on chromosome 11q13. Primary hyperparathyroidism, pancreatic gastroduodenal neuroend... | ['Adenoma', 'Adrenal Gland Neoplasms', 'Humans', 'Multiple Endocrine Neoplasia', 'Pheochromocytoma', 'Pituitary Neoplasms'] | 31,296,813 | [['C04.557.470.035'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.400', 'C04.651.600', 'C04.700.630', 'C16.320.700.630', 'C19.344.400'], ['C04.557.465.625.650.700.725', 'C04.557.580.625.650.700.725'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.... | ['Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical Analysis of Leucocyte Subsets in the Sinonasal Mucosa of Cats with Upper Respiratory Tract Aspergillosis. | Leucocyte populations in the sinonasal mucosa of cats with and without upper respiratory tract aspergillosis were compared using immunohistochemistry and computer-aided morphometry. Inflammation was identified in the nasal mucosa of all affected cats, comprising predominantly of lymphoplasmacytic infiltration of the la... | ['Animals', 'Aspergillosis', 'Cat Diseases', 'Cats', 'Female', 'Immunohistochemistry', 'Leukocytes', 'Male', 'Nasal Mucosa', 'Paranasal Sinuses', 'Respiratory Tract Infections'] | 27,576,043 | [['B01.050'], ['C01.150.703.080'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.12... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Heat shock protein 60 autoimmunity and early lipid lesions in cholesterol-fed C57BL/6JBom mice during Chlamydia pneumoniae infection. | Chronic Chlamydia pneumoniae infection and autoimmunity to heat shock protein 60 (Hsp60) have both been documented to be associated with atherosclerosis. Herein, we studied the effects of C. pneumoniae infection and a diet with a low-cholesterol supplement on the development of autoantibodies to mouse Hsp60 and early l... | ['Animals', 'Aortic Valve', 'Autoimmunity', 'Chaperonin 60', 'Chlamydia Infections', 'Chlamydophila pneumoniae', 'Cholesterol, Dietary', 'Lung Diseases', 'Mice'] | 15,530,906 | [['B01.050'], ['A07.541.510.110'], ['G12.450.192'], ['D08.811.277.040.025.142.500.500', 'D12.776.580.216.210.590.750'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.230.249'], ['D04.210.500.247.808.197.2... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unified Huntington's disease rating scale: a follow up. | An objective assessment of the clinical findings in patients with Huntington's disease (HD) is necessary for an evaluation of the longitudinal progression of the disease features. The Unified Huntington's Disease Rating Scale (UHDRS) is a scale to assess clinical performance and functional capacity. The authors examine... | ['Activities of Daily Living', 'Adult', 'Aged', 'Analysis of Variance', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Huntington Disease', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Neurologic Examination', 'Psychometrics', 'Statistics, Nonparametric'] | 9,827,615 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.98... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparison of neutrophil apoptosis, á-defensins and calprotectin in children with and without severe early childhood caries. | BACKGROUND: The infectious nature of severe early-childhood caries (S-ECC) points to the possible participation of immunologic host responses including neutrophils and their antimicrobial products.OBJECTIVES: The aim of this study was to determine the neutrophil apoptosis, á-defensins (HNP1-3) and calprotectin levels i... | ['Apoptosis', 'Child, Preschool', 'Dental Caries', 'Female', 'Humans', 'Iran', 'Leukocyte L1 Antigen Complex', 'Male', 'Neutrophils', 'Saliva', 'alpha-Defensins'] | 21,427,491 | [['G04.146.954.035'], ['M01.060.406.448'], ['C07.793.720.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['D12.776.157.125.750.500', 'D12.776.631.655.500', 'D23.050.301.562'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A1... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Hemispheric lateralization and language skill coherence in temporal lobe epilepsy. | Patients with an early onset of temporal lobe epilepsy (TLE) are at an increased risk for language reorganization. It is unknown whether this reorganization involves a full shift of all language skills to the contralateral hemisphere, or whether it can be partial and involve only a subset of language skills. In this st... | ['Adolescent', 'Adult', 'Amobarbital', 'Electroencephalography', 'Epilepsy, Temporal Lobe', 'Female', 'Functional Laterality', 'Humans', 'Language Tests', 'Male', 'Mental Recall', 'Middle Aged', 'Neuronal Plasticity', 'Reading', 'Recognition, Psychology', 'Speech Perception', 'Temporal Lobe', 'Verbal Behavior', 'Visual... | 19,286,172 | [['M01.060.057'], ['M01.060.116'], ['D03.383.742.698.253.077'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['F02.463.425.540.641'], ['M01.060.116.630'], ['G1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Cardiorenal syndrome in renal transplant recipients - It's the fistula at fault: A case series. | Complications arising from a functional arteriovenous fistula (AVF) in successful kidney transplant recipients (KT) have been overlooked despite some reports of its deleterious effect on heart, lungs, and kidney allograft. As such, there is no consensus regarding management of AVF after renal transplantation. We report... | ['Arteriovenous Fistula', 'Cardio-Renal Syndrome', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'Graft Survival', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prognosis', 'Renal Dialysis', 'Risk Factors', 'Transplant Recipients'] | 30,350,874 | [['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['C12.777.419.780.400', 'C13.351.968.419.780.400', 'C14.280.434.156'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.328'], ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Early asymmetric inter-hemispheric transfer in the auditory network: insights from infants with corpus callosum agenesis. | The left hemisphere specialization for language is a well-established asymmetry in the human brain. Structural and functional asymmetries are observed as early as the prenatal period suggesting genetically determined differences between both hemispheres. The corpus callosum is a large tract connecting mostly homologous... | ['Acoustic Stimulation', 'Agenesis of Corpus Callosum', 'Analysis of Variance', 'Auditory Pathways', 'Brain Mapping', 'Dichotic Listening Tests', 'Electroencephalography', 'Evoked Potentials, Auditory', 'Female', 'Functional Laterality', 'Humans', 'Infant', 'Male', 'Reaction Time', 'Transfer, Psychology'] | 29,687,282 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['C10.500.034', 'C16.131.666.034', 'C23.300.008'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A08.612.220.110'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.382.375.200'], ['E01.370.376.300', 'E01.370.405.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of bronchoalveolar lavage and catheter lavage to confirm ventilator-associated lower respiratory tract infection. | Lower respiratory tract infection (LRTI) is a well recognised complication of artificial ventilation in intensive care units (ICU). Ideally, specimens for microbiological analysis should be obtained during bronchoscopy, but this is not always possible. Therefore, the microbiological diagnosis of lower respiratory tract... | ['Adolescent', 'Adult', 'Aged', 'Bacteriological Techniques', 'Bronchoalveolar Lavage', 'Catheterization', 'Cell Count', 'Epithelium', 'Female', 'Gram-Negative Bacteria', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Respiratory Tract Infections', 'Staphylococcus aureus', 'Ventilators, Mechanical'] | 8,810,951 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E05.927.100'], ['E02.148', 'E05.157'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A10.272'], ['B03.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['M01.060.116.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. | It has been recently demonstrated that regulatory CD4(+)CD25(+) CD45RO(+) T cells are present in the peripheral blood of healthy adults and exert regulatory function similar to their rodent counterparts. It remains difficult to understand how the small fraction of these T cells that regulate via direct cell-to-cell con... | ['Adult', 'Animals', 'CD4-Positive T-Lymphocytes', 'Cell Adhesion', 'Clonal Anergy', 'Humans', 'In Vitro Techniques', 'Interleukin-1', 'Interleukin-10', 'Leukocyte Common Antigens', 'Lymphocyte Activation', 'Protein Tyrosine Phosphatase, Non-Receptor Type 1', 'Receptors, Interleukin-2', 'T-Lymphocytes'] | 12,119,349 | [['M01.060.116'], ['B01.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.022'], ['G12.535.425.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pulmonary hypertension and pulmonary artery dissection. | Pulmonary artery dissection is a fatal complication of long-standing pulmonary hypertension, manifesting as acute, stabbing chest pain, progressive dyspnea, cardiogenic shock, or sudden death. Its incidence has been underestimated, and therapeutic options are still scarce. In patients with pulmonary hypertension, new c... | ['Aneurysm, Dissecting', 'Chest Pain', 'Death, Sudden', 'Fatal Outcome', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Pulmonary Artery', 'Shock, Cardiogenic', 'Ultrasonography'] | 23,670,510 | [['C14.907.055.050'], ['C23.888.592.612.233'], ['C23.550.260.322'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.116.630'], ['A07.015.114.715'], ['C14.280.6... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Experimental population design for estimation of dominant molecular marker effect on egg-production traits. | A potential limitation of the use of a dominant molecular marker system such as DNA fingerprinting (DFP) is the inability to distinguish homozygous from heterozygous allele state in an individual, and a resulting inaccuracy in estimating effects of the marker alleles. The objective of this study was to accurately estim... | ['Alleles', 'Animals', 'Chickens', 'Crosses, Genetic', 'Genetic Markers', 'Ovum', 'Quantitative Trait Loci'] | 14,510,668 | [['G05.360.340.024.340.030'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.393.281'], ['D23.101.387', 'G05.695.450'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['G05.360.340.024.380.937']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Candidatus Cryptoplasma Associated with Green Lizards and Ixodes ricinus Ticks, Slovakia, 2004-2011. | During 2004-2011, we collected green lizards and Ixodes ricinus ticks in Slovak Karst National Park in Slovakia; 90% (36/40) of lizards and 37% of ticks removed from lizards were infected with family Anaplasmataceae bacteria. Only Candidatus Cryptoplasma sp. REP (reptile) was identified in these samples. Green lizards ... | ['Alphaproteobacteria', 'Animals', 'Bacterial Infections', 'Disease Reservoirs', 'Female', 'History, 21st Century', 'Humans', 'Ixodes', 'Lizards', 'Male', 'Phylogeny', 'Polymorphism, Single-Stranded Conformational', 'Public Health Surveillance', 'RNA, Ribosomal, 16S', 'Slovakia'] | 30,457,527 | [['B03.660.050'], ['B01.050'], ['C01.150.252'], ['N06.850.520.203.250'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.131.166.132.832.400.425'], ['B01.050.150.900.833.393'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.365.795.600'], ['E05.318.308.980.438.700.324', 'N05.715.36... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Kinetics of pulmonary gas exchange during and while recovering from exercise in patients after anterior myocardial infarction. | The effect of exercise intensity on gas exchange kinetics was investigated during exercise and recovery, as well as the relationship between the kinetics during exercise and recovery. Twenty-three patients with a history of anterior myocardial infarction performed low-intensity (38.7+/-8.3 W) and high-intensity (68.8+/... | ['Adult', 'Aged', 'Carbon Dioxide', 'Electrocardiography', 'Exercise', 'Exercise Test', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Kinetics', 'Linear Models', 'Male', 'Middle Aged', 'Models, Biological', 'Myocardial Infarction', 'Oxygen', 'Pulmonary Gas Exchange', 'Respiration', 'Time Factors', 'Ventricular Dys... | 10,406,586 | [['M01.060.116'], ['M01.060.116.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E01.370.370.380.240', 'E01.370.405.240'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. | Salmonella enterica subspecies I, serovar Typhimurium (S. typhimurium), is a leading cause of human gastroenteritis, and is used as a mouse model of human typhoid fever. The incidence of non-typhoid salmonellosis is increasing worldwide, causing millions of infections and many deaths in the human population each year. ... | ['Animals', 'Chromosomes, Bacterial', 'DNA, Bacterial', 'Enterobacteriaceae', 'Escherichia coli', 'Fimbriae, Bacterial', 'Genes, Bacterial', 'Genome, Bacterial', 'Humans', 'Molecular Sequence Data', 'Plasmids', 'Pseudogenes', 'Salmonella Vaccines', 'Salmonella typhimurium', 'Sequence Analysis, DNA', 'Species Specificit... | 11,677,609 | [['B01.050'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['D13.444.308.212'], ['B03.440.450.425', 'B03.660.250.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.284.180.285', 'A20.843'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.358.2... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Developmental aspects of timing behavior in children. | This research examined the association of age, sex, and intelligence on the performance of a time production (temporal response differentiation, TRD) task. Variations of this task have been used extensively with both animals and humans to study factors that affect aspects of timing ability. The participants in this stu... | ['Age Factors', 'Analysis of Variance', 'Child', 'Child Development', 'Child, Preschool', 'Female', 'Humans', 'Intelligence', 'Intelligence Tests', 'Male', 'Problem Solving', 'Psychomotor Performance', 'Reaction Time', 'Reward', 'Task Performance and Analysis', 'Time Factors', 'Time Perception'] | 15,113,607 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['F04.711.141.493'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.808',... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
4'-Acetamidochalcone derivatives as potential antinociceptive agents. | Nine acetamidochalcones were synthesized and evaluated as antinociceptive agents using the mice writhing test. Given intraperitoneally all the compounds were more effective than the two reference analgesic drugs (acetylsalicylic acid and acetaminophen) used for comparison. N-{4-[(2E)-3-(4-nitrophenyl)prop-2-enoyl]pheny... | ['Acetamides', 'Acetaminophen', 'Analgesics', 'Animals', 'Aspirin', 'Chalcone', 'Chalcones', 'Chromatography, Thin Layer', 'Drug Design', 'Drug Evaluation, Preclinical', 'Formaldehyde', 'Inflammation', 'Infusions, Parenteral', 'Magnetic Resonance Spectroscopy', 'Mice', 'Models, Chemical'] | 17,851,442 | [['D02.065.064', 'D02.241.081.018.110'], ['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['D02.522.818.222.500', 'D03.633.100.150.266.450.221.500'], ['D02.522.818.222', 'D03.383.663.283.266.450.221', 'D03.633.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptional rate and steady-state changes of retinoblastoma mRNA in regenerating rat liver. | This study characterizes the mRNA expression of the retinoblastoma tumor suppressor gene in regenerating rat liver during 96 hr after 70% partial hepatectomy. A 960-bp BglII-OxaNI fragment of murine retinoblastoma cDNA was used to probe Northern blots of poly(A)(+)-enriched RNA isolated from regenerating liver. Two spe... | ['Animals', 'Gene Expression Regulation', 'Genes, Retinoblastoma', 'Half-Life', 'Hepatectomy', 'Liver Regeneration', 'Male', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Time Factors', 'Transcription, Genetic', 'Transforming Growth Factor alpha'] | 8,175,144 | [['B01.050'], ['G05.308'], ['G05.360.340.024.340.375.249.400', 'G05.360.340.024.340.415.400.400'], ['G01.910.405'], ['E04.210.556'], ['G10.261.475', 'G16.762.468'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G01.910.857'], ['G02.111.873', 'G05.29... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Migration of endophytic diazotroph Azorhizobium caulinodans ORS571 inside wheat (Triticum aestivum L) and its effect on microRNAs. | Azorhizobium caulinodans ORS571, a novel rhizobium, forms endosymbionts with its nature host Sesbania rostrata, a semi-aquatic leguminous tree. Recent studies showed that A. caulinodans ORS571, as endophytic rhizobium, disseminated and colonized inside of cereal plants. However, how this rhizobium infects monocot plant... | ['Azorhizobium caulinodans', 'MicroRNAs', 'Triticum'] | 27,858,182 | [['B03.440.400.425.127.100', 'B03.585.110.100', 'B03.660.050.350.080.100'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['B01.650.940.800.575.912.250.822.918']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A New Electrocardiographic Marker of Sudden Death in Brugada Syndrome: The S-Wave in Lead I. | BACKGROUND: Risk stratification in asymptomatic patients remains by far the most important yet unresolved clinical problem in the Brugada syndrome (BrS).OBJECTIVES: This study sought to analyze the usefulness of electrocardiographic parameters as markers of sudden cardiac death (SCD) in BrS.METHODS: This study analyzed... | ['Brugada Syndrome', 'Death, Sudden, Cardiac', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Prevalence', 'Prognosis', 'Prospective Studies', 'Risk Assessment', 'Survival Rate', 'Time Factors'] | 27,012,403 | [['C14.280.067.322', 'C14.280.123.250', 'C16.320.100'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630']... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Incremental generation of answers during the comprehension of questions with quantifiers. | The paper presents a study on the online interpretation of quantified questions involving complex domain restriction, for instance, are all triangles blue that are in the circle. Two probe reaction time (RT) task experiments were conducted to study the incremental nature of answer generation while manipulating visual c... | ['Comprehension', 'Female', 'Humans', 'Language', 'Male', 'Reaction Time', 'Visual Perception', 'Young Adult'] | 28,599,167 | [['F02.463.188.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.932'], ['M01.060.116.815']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Psychosocial changes as correlates of weight regain vs. continued loss within 2-year trials of a self-regulation-focused community-based intervention. | Although health-enhancing weight reductions are associated with behavioural treatments initially, a trajectory towards full regain typically begins within 6-9 months. Women with obesity (body mass index = 30-40 kg m-2 ) who lost at least 3% of their baseline weight within two trials of a new cognitive-behavioural treat... | ['Adult', 'Cognitive Behavioral Therapy', 'Exercise', 'Feeding Behavior', 'Female', 'Fruit', 'Health Behavior', 'Humans', 'Longitudinal Studies', 'Middle Aged', 'Obesity', 'Self Efficacy', 'United States', 'Vegetables', 'Weight Gain', 'Weight Loss', 'Weight Reduction Programs'] | 28,079,977 | [['M01.060.116'], ['F04.754.137.350'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Di... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Sonographic assessment of fetal occiput position during labor for the prediction of labor dystocia and perinatal outcomes. | OBJECTIVES: To evaluate the effect of the occiput posterior (OP) position on dystocia and perinatal outcomes.METHODS: This was a prospective cohort study of 162 primiparous women. We performed intrapartum sonography, and fetal occiput positions were recorded. The relationships between the position of the occiput and th... | ['Adult', 'Delivery, Obstetric', 'Dystocia', 'Female', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Labor Presentation', 'Labor Stage, First', 'Labor Stage, Second', 'Logistic Models', 'Pregnancy', 'Prospective Studies', 'Sensitivity and Specificity', 'Ultrasonography, Prenatal'] | 26,948,718 | [['M01.060.116'], ['E04.520.252'], ['C13.703.420.288'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.520', 'G08.686.784.769.326.520'], ['G08.686.784.769.326.500.080'], ['G08.686.784.769.326.500.090'], ['E05.318.740.500.525', 'E05.318.740.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthetic lethal screening in the mammalian central nervous system identifies Gpx6 as a modulator of Huntington's disease. | Huntington's disease, the most common inherited neurodegenerative disease, is characterized by a dramatic loss of deep-layer cortical and striatal neurons, as well as morbidity in midlife. Human genetic studies led to the identification of the causative gene, huntingtin. Recent genomic advances have also led to the ide... | ['Animals', 'Behavior, Animal', 'Central Nervous System', 'Disease Models, Animal', 'Gene Expression Regulation', 'Glutathione Peroxidase', 'Humans', 'Huntington Disease', 'Mice', 'Motor Activity', 'Neostriatum'] | 25,535,386 | [['B01.050'], ['F01.145.113'], ['A08.186'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.308'], ['D08.811.682.732.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.545', 'C10.228.140.380.278', 'C10.228.662.262.249.750', 'C10.574.500.497', 'C16.320.400.430', 'F03.615.250.400', 'F03.615.40... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
National outbreak of Acanthamoeba keratitis associated with use of a contact lens solution, United States. | An outbreak of Acanthamoeba keratitis, a rare, potentially blinding, corneal infection, was detected in the United States in 2007; cases had been increasing since 2004. A case-control study was conducted to investigate the outbreak. We interviewed 105 case-patients from 30 states and 184 controls matched geographically... | ['Acanthamoeba', 'Acanthamoeba Keratitis', 'Adolescent', 'Adult', 'Aged', 'Animals', 'Case-Control Studies', 'Child', 'Communicable Diseases, Emerging', 'Contact Lens Solutions', 'Disease Outbreaks', 'Drug Contamination', 'Female', 'Humans', 'Male', 'Middle Aged', 'United States', 'Young Adult'] | 19,751,585 | [['B01.046.500.100.075.080'], ['C01.610.300.125', 'C01.610.752.049.203', 'C11.204.564.112', 'C11.294.725.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['C01.221.500', 'C23.550.291.531.750'], ['D2... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
White matter fiber tractography via anisotropic diffusion simulation in the human brain. | A novel approach to noninvasively tracing brain white matter fiber tracts is presented using diffusion tensor magnetic resonance imaging (DT-MRI). This technique is based on successive anisotropic diffusion simulations over the human brain, which are utilized to construct three dimensional diffusion fronts. The fiber p... | ['Algorithms', 'Anisotropy', 'Artificial Intelligence', 'Brain', 'Computer Simulation', 'Diffusion Magnetic Resonance Imaging', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Models, Neurological', 'Nerve Fibers, Myelinated', 'Neural Pathways', 'Pattern Recognit... | 16,156,351 | [['G17.035', 'L01.224.050'], ['G01.590.040', 'G02.050'], ['G17.035.250', 'L01.224.050.375'], ['A08.186.211'], ['L01.224.160'], ['E01.370.350.825.500.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A novel dextran hydrogel linking trans-ferulic acid for the stabilization and transdermal delivery of vitamin E. | Long-term exposure of the skin to UV light causes degenerative effects, which can be minimized by using antioxidant formulations. The major challenge in this regard is that a significant amount of antioxidant should reach at the site for effective photoprotection. However, barrier properties of the skin limit their use... | ['Administration, Cutaneous', 'Animals', 'Coumaric Acids', 'Dextrans', 'Free Radicals', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Hydrogels', 'Magnetic Resonance Spectroscopy', 'Malondialdehyde', 'Methacrylates', 'Oxidants', 'Polymers', 'Rabbits', 'Skin', 'Ultraviolet Rays', 'Vitamin E', 'tert-Butylhydroperoxide... | 18,976,708 | [['E02.319.267.120.060'], ['B01.050'], ['D02.241.223.200.210'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D01.339', 'D02.389'], ['D02.033.455.250.700.485', 'D05.750.219.500', 'D05.750.741.485', 'D20.280.320.609.500', 'D25.720.532.500', 'D25.720.741.485', 'D26.255.165.320.375.375', 'J01.637.051.720.584.500', 'J01.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Bone mineralization in former very low birth weight infants fed either human milk or commercial formula. | The bone mineral status of former very low birth weight infants previously fed fortified human milk was evaluated during the posthospitalization period. Anthropometric measurements, bone mineral content, bone width, serum calcium, phosphorus, and albumin concentrations, and alkaline phosphatase activity were evaluated ... | ['Alkaline Phosphatase', 'Bone and Bones', 'Female', 'Food, Fortified', 'Humans', 'Infant', 'Infant Food', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Male', 'Milk, Human', 'Minerals', 'Phosphorus'] | 3,373,406 | [['D08.811.277.352.650.035'], ['A02.835.232', 'A10.165.265'], ['G07.203.300.515', 'J02.500.515'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.300.525.500', 'J02.500.525.500'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Timing of initiation of renal replacement therapy for acute kidney injury: a survey of nephrologists and intensivists in Canada. | BACKGROUND: Little is known about factors that influence the timing of initiation of renal replacement therapy (RRT) for acute kidney injury (AKI). We sought to better describe these factors for Canadian physicians that prescribe RRT for AKI.METHODS: A web-based survey was conducted of physicians involved in the decisi... | ['Acute Kidney Injury', 'Aged', 'Canada', 'Critical Care', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nephrology', 'Physicians', 'Renal Replacement Therapy', 'Time Factors', 'Treatment Outcome'] | 22,207,332 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['Z01.107.567.176'], ['E02.760.190', 'N02.421.585.190'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.403.429.580'], ['M01.526.485.810',... | ['Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Interest in the serum color as an indirect criterion of selection of digestive efficiency in chickens. | Improving the digestive efficiency of birds is becoming increasingly important with the diversification of feedstuffs used in poultry diets. Compared with time-consuming chemical analyses that were previously used to measure digestive efficiency, near-infrared spectroscopy has been a great advance as it was fast and th... | ['Animal Feed', 'Animal Husbandry', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Biomarkers', 'Chickens', 'Color', 'Diet', 'Digestion', 'Female', 'Heredity', 'Male', 'Phenotype', 'Selection, Genetic', 'Serum'] | 32,036,974 | [['G07.203.300.300.100', 'J02.500.300.100'], ['J01.040.090'], ['G07.203.650.161'], ['B01.050'], ['D23.101'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G01.590.540.199'], ['G07.203.650.240'], ['G07.203.650.250', 'G10.261.190'], ['G05.390'], ['G05.695'], ['G05.783'], ['A12.207.152.846', 'A15.145.8... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evidence for minor structural variations of class II genes in wild and inbred mice. | We organized 29 B10.W lines into eight antigenic groups on the basis of similarities in the antigenic phenotypes of their class II antigens. Tryptic peptide fingerprint comparisons of class II antigens in different antigenic groups detected structural variations in 30 to 60% of the tryptic peptides. In contrast, less t... | ['Animals', 'Chemical Phenomena', 'Chemistry', 'Genes, MHC Class II', 'Genetic Variation', 'H-2 Antigens', 'Histocompatibility Antigens', 'Histocompatibility Antigens Class II', 'Mice', 'Mice, Inbred A', 'Mice, Inbred C57BL', 'Muridae', 'Phenotype', 'Protein Biosynthesis', 'Species Specificity'] | 6,401,784 | [['B01.050'], ['G02'], ['H01.181'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['G05.365'], ['D23.050.301.500.100.350', 'D23.050.301.500.400.199', 'D23.050.705.552.100.350', 'D23.050.705.552.410.199'], ['D23.050.301.500', 'D23.050.705.552'], ['D12.776.395.550.509', 'D12.776.543.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Yangjing capsule plus low-dose tadalafil for functional anejaculation]. | OBJECTIVE: To search for an effective therapy for functional anejaculation (AE).METHODS: Fifty-five AE patients were randomized into a treatment group (n = 30) and a control group (n = 25), the former treated with Yangjing Capsule (once 5 pills, tid) and low-dose tadalafil (5 mg, qd alt, 1 h before bedtime), while the ... | ['Adult', 'Capsules', 'Carbolines', 'Drug Therapy, Combination', 'Drugs, Chinese Herbal', 'Humans', 'Infertility, Male', 'Male', 'Phytotherapy', 'Sexual Dysfunction, Physiological', 'Tadalafil', 'Treatment Outcome', 'Young Adult'] | 23,405,799 | [['M01.060.116'], ['D26.255.150'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['E02.319.310'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['E02.190.755'], ['C12.294.644', 'C13.351.500.665'], ['D03.383.725.150.500', 'D03.633.100.473.155.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arsenic pollution and fractionation in sediments and mine waste samples from different mine sites. | A characterization of arsenic pollution and its associations with solid mineral phases in sediments and spoil heap samples from four different abandoned mines in Spain is performed. Three of them were mercury mines located in the same mining district, in the province of Asturias, and the other one, devoted to arsenic m... | ['Arsenic', 'Chemical Fractionation', 'Environmental Pollutants', 'Ferric Compounds', 'Geologic Sediments', 'Mercury', 'Mercury Compounds', 'Mining', 'Spain'] | 22,704,004 | [['D01.268.513.249'], ['E05.196.155'], ['D27.888.284'], ['D01.490.100'], ['G01.311.330', 'G16.500.320'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D01.538'], ['J01.576.655.875.500'], ['Z01.542.846']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Evidence for an essential arginine residue in the active site of Escherichia coli 2-keto-4-hydroxyglutarate aldolase. Modification with 1,2-cyclohexanedione. | Treatment of homogeneous preparations of Escherichia coli 2-keto-4-hydroxyglutarate aldolase with 1,2-cyclohexanedione, 2,3-butanedione, phenylglyoxal, or 2,4-pentanedione results in a time- and concentration-dependent loss of enzymatic activity; the kinetics of inactivation are pseudo-first order. Cyclohexanedione is ... | ['Amino Acids', 'Arginine', 'Binding Sites', 'Cyclohexanes', 'Cyclohexanones', 'Escherichia coli', 'Kinetics', 'Oxo-Acid-Lyases'] | 3,886,656 | [['D12.125'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G02.111.570.120'], ['D02.455.426.392.368.367'], ['D02.455.426.392.368.367.340', 'D02.522.400'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['D08.811.520.224.600']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Activity of blood serum enzymes in alpha-tocopheryl acetate administered rats with experimental myocardial infarction]. | The experimental myocardial infarction induced in rats by ligation of the descending branch of the coronary artery increases the activity of creatine phosphokinase, aspartate and alanine aminotransferases in blood serum. Administration of vitamin E promotes a reduction of excessive content of enzymes in the acute perio... | ['Alanine Transaminase', 'Animals', 'Aspartate Aminotransferases', 'Creatine Kinase', 'Disease Models, Animal', 'Male', 'Myocardial Infarction', 'Rats', 'Tocopherols', 'Vitamin E', 'alpha-Tocopherol'] | 7,281,246 | [['D08.811.913.477.700.100'], ['B01.050'], ['D08.811.913.477.700.225'], ['D08.811.913.696.640.150'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['D03.383.663.283.909.750', 'D03.633.100.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
cDNA cloning and mRNA expression of retinoid-X-receptor in the ovary of the shrimp Metapenaeus ensis. | Retinoid-X-receptor (RXR) plays an essential role in the molting process of decapod crustaceans, by forming a heterodimeric complex with the ecdysteroid receptor. However, its role during female reproduction, especially in the process of ovarian maturation, has not been characterized. To get an insight into the molecul... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'DNA, Complementary', 'Female', 'Gene Expression', 'Gene Expression Regulation', 'Molecular Sequence Data', 'Organ Specificity', 'Ovary', 'Penaeidae', 'Phylogeny', 'Retinoid X Receptors', 'Retinoids', 'Sequence Alignment', 'Transcriptome'] | 24,091,942 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.297'], ['G05.308'], ['L01.453.245.667'], ['G07.650'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Effect of Conditioning Agent Combined with Flooding Measures on Absorption and Accumulation of Cadmium in Rice]. | In order to evaluate the effects and mechanisms of flooding measures, soil conditioner, silicon mineral fertilizer and sprayed foliar fertilizer, gypsum powder, and their multiple treatments for reducing Cd accumulation in rice grown in Cd-contaminated soil. A plot experiment was conducted in three different Cd-contami... | ['Cadmium', 'Fertilizers', 'Floods', 'Oryza', 'Soil', 'Soil Pollutants'] | 31,854,896 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D27.720.031.400'], ['G16.500.175.812', 'N06.230.100.230.250'], ['B01.650.940.800.575.912.250.822.616'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Unrestricted evening use of light-emitting tablet computers delays self-selected bedtime and disrupts circadian timing and alertness. | Consumer electronic devices play an important role in modern society. Technological advancements continually improve their utility and portability, making possible the near-constant use of electronic devices during waking hours. For most people, this includes the evening hours close to bedtime. Evening exposure to ligh... | ['Adult', 'Brain', 'Circadian Rhythm', 'Computers, Handheld', 'Electroencephalography', 'Female', 'Humans', 'Light', 'Male', 'Melatonin', 'Sleep', 'Wakefulness', 'Young Adult'] | 29,845,764 | [['M01.060.116'], ['A08.186.211'], ['G07.180.562.190'], ['L01.224.230.260.550.500'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D03.633.100.473.914.481', 'D06.472.506'], ['F02.830.855', 'G11.561... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Phosphoketolase pathway contributes to carbon metabolism in cyanobacteria. | Central carbon metabolism in cyanobacteria comprises the Calvin-Benson-Bassham (CBB) cycle, glycolysis, the pentose phosphate (PP) pathway and the tricarboxylic acid (TCA) cycle. Redundancy in this complex metabolic network renders the rational engineering of cyanobacterial metabolism for the generation of biomass, bio... | ['Acetates', 'Aldehyde-Lyases', 'Aldose-Ketose Isomerases', 'Bacterial Proteins', 'Carbon', 'Genetic Complementation Test', 'Heterotrophic Processes', 'Ketoglutaric Acids', 'Nitrogen', 'Pentosephosphates', 'Phosphotransferases (Alcohol Group Acceptor)', 'Synechocystis', 'Xylose'] | 27,250,745 | [['D02.241.081.018', 'D10.251.400.045'], ['D08.811.520.224.062'], ['D08.811.399.475.200'], ['D12.776.097'], ['D01.268.150'], ['E05.393.281.526'], ['G02.111.375', 'G03.393'], ['D02.241.081.337.351.502', 'D02.241.755.465'], ['D01.268.604', 'D01.362.625'], ['D09.894.643'], ['D08.811.913.696.620'], ['B03.280.750', 'B03.440... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vital Signs: Trends in Human Rabies Deaths and Exposures - United States, 1938-2018. | INTRODUCTION: Each year, rabies causes approximately 59,000 deaths worldwide, including approximately two deaths in the United States. Before 1960, dogs were a common reservoir of rabies in the United States; however, increasingly, species of wildlife (e.g., bats, raccoons) are the main reservoirs. This report characte... | ['Animals', 'Bites and Stings', 'Chiroptera', 'Dog Diseases', 'Dogs', 'Environmental Exposure', 'Humans', 'Internationality', 'Mortality', 'Population Surveillance', 'Post-Exposure Prophylaxis', 'Rabies', 'Risk Factors', 'Travel-Related Illness', 'United States'] | 31,194,721 | [['B01.050'], ['C25.723.127', 'C26.176'], ['B01.050.150.900.649.313.937'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['E05.... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Determination of fatty acid amides as trimethylsilyl derivatives by gas chromatography with mass spectrometric detection. | Fatty acid amides are a newly emerging class of compounds with biological activity. The amides are formed enzymatically in vivo. Analysis of fatty acid amides has been accomplished by gas chromatography coupled with mass spectrometry. Fatty acid amides required derivatization prior to analysis at high temperatures due ... | ['Amides', 'Fatty Acids', 'Gas Chromatography-Mass Spectrometry', 'Trimethylsilyl Compounds'] | 10,457,449 | [['D02.065'], ['D10.251'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.756.715']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphorylation of Ser-180 of rat aquaporin-4 shows marginal affect on regulation of water permeability: molecular dynamics study. | Water permeation through rat aquaporin-4 (rAQP4), predominantly found in mammalian brain is regulated by phosphorylation of Ser-180. The present study has been carried out to understand the structural mechanism of regulation of water permeability across the channel. Molecular dynamics (MD) simulations have been carried... | ['Animals', 'Aquaporin 4', 'Molecular Dynamics Simulation', 'Permeability', 'Phosphorylation', 'Protein Conformation', 'Protein Interaction Domains and Motifs', 'Rats', 'Serine', 'Water'] | 23,651,078 | [['B01.050'], ['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.723'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G02.111.570.820.709'], ['G02.111.570.820.709.275.750.500'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Influences of frailty syndrome on open-loop and closed-loop postural control strategy. | BACKGROUND: As the population of older adults quickly increases, the incidence of frailty syndrome, a reduction in physiological reserve across multiple physiological systems, likewise increases. To date, impaired balance has been associated with frailty; however, the underlying frailty-related postural balance mechani... | ['Aged', 'Aged, 80 and over', 'Aging', 'Female', 'Frail Elderly', 'Humans', 'Logistic Models', 'Male', 'Postural Balance', 'Proprioception', 'Visual Perception'] | 25,278,191 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['M01.060.116.100.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates. | NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) catalyzes the oxidation of the 15(S) hydroxyl group of prostaglandins to a 15-keto group resulting in a significant reduction of the biological activities of prostaglandins. Although the key residues involved in NAD+ binding and in catalytic activity have b... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Western', 'Catalysis', 'DNA Primers', 'DNA, Complementary', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Hydroxyprostaglandin Dehydrogenases', 'Molecular Sequence Data', 'NAD', 'Prostaglandins', 'Rats', 'Recombinant Fusion Proteins', 'Sequence Homology... | 11,422,365 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G02.130'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.497.220', 'D13.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Redox processes in allergic reactions of the delayed type to microbial antigens]. | The influence of common allergic response of delayed type to brucellosis antigen on the processes of glycolysis and dehydrogenase activity of Krebs' cycle in guinea pigs' blood and organs was studied. Along with inhibitory activity of four dehydrogenases investigated there was a depression of the glucolysis processes c... | ['Animals', 'Antigens, Bacterial', 'Brucella abortus', 'Citric Acid Cycle', 'Glycolysis', 'Guinea Pigs', 'Hypersensitivity, Delayed', 'Isocitrate Dehydrogenase', 'L-Lactate Dehydrogenase', 'Lactates', 'Malate Dehydrogenase', 'Organ Specificity', 'Oxidoreductases', 'Pyruvates'] | 100,150 | [['B01.050'], ['D23.050.161'], ['B03.440.400.425.215.500.100', 'B03.660.050.070.100.100'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['B01.050.150.900.649.313.992.550'], ['C20.543.418'], ['D08.811.682.047.820.475'], ['D08.811.682.047.551.400', 'D08.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elastic strain and twist analysis of protein structural data and allostery of the transmembrane channel KcsA. | The abundance of available static protein structural data makes the more effective analysis and interpretation of this data a valuable tool to supplement the experimental study of protein mechanics. Structural displacements can be difficult to analyze and interpret. Previously, we showed that strains provide a more nat... | ['Allosteric Regulation', 'Bacterial Proteins', 'Biomechanical Phenomena', 'Potassium Channels', 'Protein Conformation', 'Streptomyces lividans'] | 29,116,053 | [['G02.111.044'], ['D12.776.097'], ['G01.154.090', 'G01.374.089'], ['D12.776.157.530.400.600', 'D12.776.543.550.450.750', 'D12.776.543.585.400.750'], ['G02.111.570.820.709'], ['B03.300.390.400.810.768.500', 'B03.510.024.997.775.500', 'B03.510.415.400.810.768.500', 'B03.510.460.410.810.768.500']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The multi-factorial model of satisfaction of medical care by hospital patients suffering from borderline psychic disorders]. | The satisfaction of patients with medical care determines their consumer behavior. The factors of satisfaction with medical care vary depending on level of its provision and profile of medical specialty. At that, there are only sporadic studies dedicated to factors of satisfaction with psychiatric care. The study was c... | ['Adult', 'Anxiety Disorders', 'Depressive Disorder', 'Hospitals, Psychiatric', 'Humans', 'Neuroticism', 'Patient Satisfaction'] | 26,012,273 | [['M01.060.116'], ['F03.080'], ['F03.600.300'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.723'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is selecting better than modifying? An investigation of arguments against germline gene editing as compared to preimplantation genetic diagnosis. | BACKGROUND: Recent scientific advances in the field of gene editing have led to a renewed discussion on the moral acceptability of human germline modifications. Gene editing methods can be used on human embryos and gametes in order to change DNA sequences that are associated with diseases. Modifying the human germline,... | ['Gene Editing', 'Genetic Enhancement', 'Germ Cells', 'Humans', 'Morals', 'Personal Autonomy', 'Personhood', 'Philosophy, Medical', 'Preimplantation Diagnosis', 'Prejudice', 'Reproductive Medicine'] | 31,752,935 | [['E05.393.420.270'], ['E05.104.500', 'E05.393.420.451', 'J01.897.120.050.250.500'], ['A05.360.490', 'A11.497'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['F02.600', 'I01.880.604.473.380.500', 'K01.752.566.479.830.650', 'N03.706.437.380.500', 'N05.350.958.650'], ['K01.752.566.479... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Convergent validity of the international physical activity questionnaire (IPAQ): meta-analysis. | OBJECTIVE: The purpose of the present study was to use a meta-analytic approach to examine the convergent validity of the international physical activity questionnaire (IPAQ).DESIGN: Systematic review by meta-analysis.SETTING: The relevant studies were surveyed from five electronic databases. Primary outcomes of intere... | ['Exercise', 'Humans', 'Reproducibility of Results', 'Surveys and Questionnaires'] | 22,874,087 | [['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
A new potent inhibitor of horse liver alcohol dehydrogenase: p-methylbenzyl hydroperoxide. | A product of p-xylene auto-oxidation, p-methylbenzyl hydroperoxide, acts as a very strong reversible inhibitor of the ethanol dehydrogenating activity of horse liver alcohol dehydrogenase. Concentrations of hydroperoxide as low as that of the enzyme active site (about 10(-8) mol.dm-3) in the assay depresses the activit... | ['Alcohol Dehydrogenase', 'Animals', 'Benzyl Compounds', 'Horses', 'In Vitro Techniques', 'Kinetics', 'Liver', 'Peroxides'] | 1,610,388 | [['D08.811.682.047.820.250'], ['B01.050'], ['D02.455.426.559.389.140'], ['B01.050.150.900.649.313.984.235.472'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D01.248.497.158.685.750', 'D01.339.431.374', 'D01.650.550.750', 'D02.389.338']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Atrial natriuretic peptide relaxes arterial basal tone induced by coarctation hypertension. | We have investigated the vasorelaxant effect of atrial natriuretic peptide (ANP) on isolated non-contracted aorta from coarctation hypertensive rats (HR) and the role of endothelium in this vasorelaxant action. After 7-14 days of surgery, mean blood pressure was higher (P < 0.01) in HR compared with sham operated rats ... | ['Acetylcholine', 'Animals', 'Aorta, Abdominal', 'Aorta, Thoracic', 'Atrial Natriuretic Factor', 'Calcium', 'Endothelium, Vascular', 'Hypertension', 'Isometric Contraction', 'Male', 'Muscle Relaxation', 'Muscle Tonus', 'Muscle, Smooth, Vascular', 'Protein Kinase C', 'Rats', 'Rats, Sprague-Dawley'] | 10,458,519 | [['D02.092.211.111'], ['B01.050'], ['A07.015.114.056.205'], ['A07.015.114.056.372'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A07.015.700.500', 'A10.272.491.355'], ['C14.907.489'], ['G11.427.494.472'], ['G11.427.494.554'], ['G11.427.565'], ['A02.633.570.49... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of ascorbic acid on the induction of uterine sarcomas in mice]. | Administration of ascorbic acid (0.3, 0.75 or 1.5%) in drinking water started after the treatment of female CBA mice with 1,2-dimethylhydrazine and estradiol-dipropionate inhibited the growth of uterine sarcomas. The inhibitory effect depended upon dosage to some extent. When administered together with estradiol-diprop... | ['1,2-Dimethylhydrazine', 'Animals', 'Ascorbic Acid', 'Body Weight', 'Dimethylhydrazines', 'Estradiol', 'Estrogen Antagonists', 'Female', 'Mice', 'Mice, Inbred CBA', 'Organ Size', 'Sarcoma, Experimental', 'Uterine Neoplasms', 'Uterus'] | 3,686,923 | [['D02.442.600.400.200'], ['B01.050'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.442.600.400'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.347.295', 'D27.505... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exercise training improves neurovascular control and functional capacity in heart failure patients regardless of age. | BACKGROUND: Exercise training is a non-pharmacological strategy for treatment of heart failure. Exercise training improves functional capacity and quality of life in patients. Moreover, exercise training reduces muscle sympathetic nerve activity (MSNA) and peripheral vasoconstriction. However, most of these studies hav... | ['Adult', 'Age Factors', 'Aged', 'Brazil', 'Exercise Therapy', 'Exercise Tolerance', 'Female', 'Forearm', 'Heart Failure', 'Hemodynamics', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Muscle, Skeletal', 'Oxygen Consumption', 'Peroneal Nerve', 'Plethysmography', 'Recovery of Function', '... | 21,697,210 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.107.757.176'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['G11.427.680.270'], ['A01.378.800.585'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Treatment of local recurrences of rectal carcinoma. | From 1978-1992, 159 patients were treated for local recurrences of rectal carcinoma. They could be subdivided into three groups according to the type of primary treatment given; 82 patients underwent primary surgery without irradiation, 37 patients had preoperative and 40 patients postoperative radiotherapy. The locali... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Combined Modality Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Palliative Care', 'Prognosis', 'Radiotherapy Dosage', 'Rectal Neoplasms', 'Retrospective Studies', 'Survival Rate'] | 7,543,209 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E02.760.666', 'N02.421.585.666'], ['E01.789'], ['E02.815.639'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of orthostatic stress on umbilical Doppler waveforms in normal and hypertensive pregnancies. | OBJECTIVE: Our study examined the effects of orthostatic stress and maternal hemodynamics on umbilical systolic/diastolic ratios in normal and hypertensive pregnancies.STUDY DESIGN: Eighteen normal and 20 hypertensive third-trimester pregnancies were examined in the left lateral recumbent, sitting, and standing positio... | ['Diastole', 'Female', 'Fetus', 'Hemodynamics', 'Humans', 'Hypertension', 'Posture', 'Pregnancy', 'Pregnancy Complications, Cardiovascular', 'Reference Values', 'Systole', 'Ultrasonography, Prenatal', 'Umbilical Cord', 'Vascular Resistance'] | 1,530,017 | [['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['A16.378'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['G11.427.695'], ['G08.686.784.769'], ['C13.703.634', 'C14.583'], ['E05.978.810'], ['G09.330.580.880', 'G11.427.494.570.880'], ['E01.370.350.850.865', 'E01.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hip, Knee, and Ankle Functional Demand During Habitual and Fast-Pace Walking in Younger and Older Women. | This study compared functional demand (FD) between older and younger women walking at habitual and fast speed and determined strength thresholds necessary to maintain FD below 80%. FD was calculated by expressing walking flexion and extension joint torques of the ankle, knee, and hip as a percentage of maximal strength... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Ankle Joint', 'Female', 'Hip Joint', 'Humans', 'Knee Joint', 'Middle Aged', 'Muscle Strength', 'Range of Motion, Articular', 'Torque', 'Walking', 'Walking Speed', 'Young Adult'] | 30,117,347 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['A02.835.583.378.062'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['M01.060.116.630'], ['E01.370.600.425', 'G11.427.560'], ['E01.370.600.700', 'G11.427.760'], ['G01.374.860.5... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Visible signs of illness from the 14th to the 20th century: systematic review of portraits. | OBJECTIVES: To see whether a collection of portraits depicting inhabitants of a defined geographical region and covering several centuries is a useful source for studying the sociocultural significance and epidemiology of particular visible diseases, such as goitre, which is known to have been common in this region.DES... | ['Female', 'Goiter', 'History, 15th Century', 'History, 16th Century', 'History, 19th Century', 'History, 20th Century', 'History, Medieval', 'Humans', 'Male', 'Medicine in the Arts', 'Obesity', 'Portraits as Topic'] | 12,493,682 | [['C19.874.283'], ['K01.400.475.500'], ['K01.400.475.750'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.093.530'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['K01.093.742']] | ['Diseases [C]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visual illusions and the control of children arm movements. | The aim of the present study was to determine whether children like adults (Gentilucci M, Chieffi S, Daprati E, Saetti MC, Toni I. Visual illusion and action. Neuropsychologia 1996;34:369-76; Gentilucci M, Daprati E, Gangitano M, Toni I. Eye position tunes the contribution of allocentric and egocentric information to t... | ['Acceleration', 'Adult', 'Analysis of Variance', 'Arm', 'Child', 'Female', 'Humans', 'Male', 'Movement', 'Optical Illusions', 'Psychomotor Performance', 'Psychophysics', 'Visual Perception'] | 11,163,371 | [['G01.482.107'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A01.378.800.075'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['F02.463.593.446.659'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E01.370.685', 'F04.096.753'], ['F... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Retinal topography in reef teleosts. II. Some species with prominent horizontal streaks and high-density areae. | The retinal ganglion cell layer of five species of reef teleosts was studied from Nissl-stained whole-mounts and the distribution of neural elements determined quantitatively. Iso-density contour maps of neurons in the ganglion cell layer revealed a temporal area centralis (ranging from 3.5 to 8.3 x 10(4) cells/mm2) wh... | ['Animals', 'Cell Count', 'Fishes', 'Retina', 'Retinal Ganglion Cells', 'Species Specificity', 'Vision, Ocular'] | 3,395,837 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['B01.050.150.900.493'], ['A09.371.729'], ['A08.675.650.850.875', 'A09.371.729.831.875', 'A11.671.650.850.875'], ['G16.824'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clonal chromosomal abnormalities in cutaneous T-cell lymphoma. | Chromosome analysis from stimulated and unstimulated lymphocytes of blood, skin, and lymph nodes demonstrated a clonal chromosomal abnormality in eight of 46 patients with cutaneous T-cell lymphoma (CTCL). Nonclonal abnormalities were found in nine other patients. Unstimulated lymph node cultures identified the highest... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Chromosome Aberrations', 'Chromosomes, Human, Pair 10', 'Female', 'Genetic Markers', 'Humans', 'Karyotyping', 'Lymphoma', 'Male', 'Middle Aged', 'Skin Neoplasms', 'T-Lymphocytes'] | 3,497,708 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.325.350', 'G05.360.162.520.300.325.350'], ['D23.101.387', 'G05.695.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pleomorphic carcinoma of the breast with expression of macrophage markers: report of two cases. | Pleomorphic ductal carcinoma of the breast is a rare variant included in the morphological group of infiltrating ductal carcinoma. The pleomorphic carcinoma is composed predominantly of epithelial and multinucleated tumor giant cells. We report here two cases presenting a lesion composed microscopically of a proliferat... | ['Aged', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'Biomarkers', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'ErbB Receptors', 'Female', 'Giant Cells', 'Humans', 'Keratins', 'Macrophages', 'Middle Aged', 'Receptors, Cell Surface', 'Tumor Suppressor Protein p53'] | 22,726,069 | [['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['D23.101'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['D08.811.913.696.620.682.725.400.009', 'D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of some arylhydrazones of p-aminobenzoic acid hydrazide as antimicrobial agents and their in vitro hepatic microsomal metabolism. | Benzoic acid p-amino-[(substituted phenyl/pyridyl) methylene] hydrazide derivatives were synthesised by interaction of p-aminobenzoic acid hydrazide with various aromatic aldehydes. The structures of the compounds were elucidated by use of their UV, IR, 1H-NMR and mass spectral data. These compounds were also evaluated... | ['Animals', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Bacteria', 'Fungi', 'Hydrazones', 'In Vitro Techniques', 'Male', 'Microbial Sensitivity Tests', 'Microsomes, Liver', 'Rats'] | 7,546,542 | [['B01.050'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['B03'], ['B01.300'], ['D02.442.288'], ['E05.481'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['A11.284.835.540.541'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Supplemental triiodothyronine, feeding regimens, and metabolic responses by the broiler chicken. | There are conflicting results concerning the role of the thyroid hormones in lipid metabolism. The experiments in this report were designed to examine the role of T(3) in modifying responses obtained by shifting birds from moderate to low protein diets. Birds were grown from 7 to 28 d on a diet containing 18% protein. ... | ['Animals', 'Blood Glucose', 'Chickens', 'Diet', 'Diet, Protein-Restricted', 'Fatty Acids, Nonesterified', 'Insulin-Like Growth Factor II', 'Isocitrate Dehydrogenase', 'Lipids', 'Liver', 'Malate Dehydrogenase', 'Male', 'Thyroxine', 'Triglycerides', 'Triiodothyronine'] | 10,962,195 | [['B01.050'], ['D09.947.875.359.448.500'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['E02.642.249.280', 'G07.203.650.240.280'], ['D10.251.310'], ['D12.644.276.937.420', 'D12.776.124.862.425', 'D12.776.467.937.420', 'D23.529.937.420'], ['D08.811.682.047.820.475'], ['D10'], ['A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Justification and reporting of subgroup analyses were lacking or inadequate in randomized controlled trials. | OBJECTIVES: The aim of the article was to assess the appropriateness and rationales of subgroup analyses planned in protocols of randomized controlled trials and reported in subsequent corresponding trial publications.STUDY DESIGN AND SETTING: We searched PubMed to identify trial protocols published in journals during ... | ['Data Interpretation, Statistical', 'Humans', 'Publications', 'Randomized Controlled Trials as Topic'] | 30,557,676 | [['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Tpl2 (tumor progression locus 2) phosphorylation at Thr290 is induced by lipopolysaccharide via an Ikappa-B Kinase-beta-dependent pathway and is required for Tpl2 activation by external signals. | The serine-threonine protein kinase encoded by the tumor progression locus 2 (Tpl2) proto-oncogene transduces Toll-like receptor and death receptor signals in a variety of cell types. Here we show that Tpl2 undergoes phosphorylation at Thr(290) both in cells overexpressing Tpl2 and in cells stimulated with lipopolysacc... | ['Animals', 'Binding Sites', 'Bone Marrow Cells', 'Cells, Cultured', 'Enzyme Inhibitors', 'Extracellular Signal-Regulated MAP Kinases', 'Heterocyclic Compounds, 3-Ring', 'I-kappa B Kinase', 'Immunosorbent Techniques', 'Lipopolysaccharides', 'MAP Kinase Kinase Kinases', 'Macrophages', 'Mice', 'Mice, Knockout', 'Mutagene... | 15,778,223 | [['B01.050'], ['G02.111.570.120'], ['A11.148', 'A15.378.316'], ['A11.251'], ['D27.505.519.389'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['D03.633.300'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['E05.478.566.380', 'E05.601.470.380'], ['D0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of orally administered Aloe marlothii leaves on Boophilus decoloratus tick burdens on cattle. | The effect of a decoction of pulverized aloe leaves (Aloe marlothii) mixed with tap water and administered orally through a gastric tube was determined against ticks on cattle. The decoction was administered to six randomly selected calves seven times at 3-day intervals while the remaining calves received an equivalent... | ['Administration, Oral', 'Aloe', 'Animals', 'Cattle', 'Cattle Diseases', 'Ixodidae', 'Phytotherapy', 'Plant Extracts', 'Plant Leaves', 'Reproduction', 'Tick Infestations'] | 17,342,347 | [['E02.319.267.100'], ['B01.650.940.800.575.912.250.618.100.970.500'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['B01.050.500.131.166.132.832.400'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['G08.686.784'], ['C01.610.858.211.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intercellular junctions in the Xenopus embryo prior to gastrulation. | A freeze-fracture study of Xenopus embryos at the eight-cell stage revealed the presence of tight junctions and small aggregations of 120 A diameter intramembranous particles. These aggregations consisted of up to ten particles and resembled forming gap junctions. Examination of early blastulae showed that fully develo... | ['Animals', 'Embryo, Nonmammalian', 'Intercellular Junctions', 'Xenopus'] | 965,918 | [['B01.050'], ['A13.350', 'A16.331'], ['A11.284.149.165.420'], ['B01.050.150.900.090.180.610.500']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protective effect of mucosal administration of recombinant human macrophage colony-stimulating factor (rhM-CSF) on mucosal infection of Sendai virus in mice. | We investigated the protection confered by the mucosal administration of recombinant human macrophage colony-stimulating factor (rhM-CSF) against mucosal infection of Sendai virus in mice. In an experimental infection model using Sendai virus, an intranasal (i.n.) administration of rhM-CSF (20 micrograms per mouse) 2 d... | ['Animals', 'Cytokines', 'Dose-Response Relationship, Drug', 'Immunity, Mucosal', 'Macrophage Colony-Stimulating Factor', 'Mice', 'Mice, Inbred BALB C', 'Recombinant Proteins', 'Respirovirus', 'Respirovirus Infections', 'Virus Replication'] | 9,041,671 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['G12.450.573'], ['D12.644.276.374.410.240.500', 'D12.776.395.240.500', 'D12.776.467.374.410.240.500', 'D23.529.374.410.240.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Recommendation for organization of special stroke departments (stroke units). 1997 implementation]. | Stroke units are hospital-based special wards aiming at optimal care by a specialized team with an integrated concept for patients with acute strokes. Following the initial neurological and neuroradiological evaluation, early treatment will be initiated based on the assumed pathophysiology of the stroke. Acute manageme... | ['Cerebrovascular Disorders', 'Combined Modality Therapy', 'Germany', 'Hospital Departments', 'Humans', 'Length of Stay', 'Patient Care Team', 'Quality Assurance, Health Care'] | 9,551,466 | [['C10.228.140.300', 'C14.907.253'], ['E02.186'], ['Z01.542.315'], ['N02.278.216.500.968', 'N04.452.442.452.422'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['N04.590.715'], ['N04.761.700', 'N05.700']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Impaired activation of cytosolic phospolipase A(2) in inflamed canine colonic circular muscle. | BACKGROUND & AIMS: Arachidonic acid (AA) is a critical second messenger in several cell types. We examined whether cholinergic AA acts as a second messenger in contraction of colonic circular muscle cells and if this role is altered by inflammation.METHODS: The experiments were performed on single dispersed cells. AA r... | ['Acetylcholine', 'Animals', 'Arachidonic Acid', 'Colon', 'Cytosol', 'Dogs', 'Enteritis', 'Enzyme Activation', 'Gastrointestinal Motility', 'Melitten', 'Muscle, Smooth', 'Phospholipases A'] | 10,889,155 | [['D02.092.211.111'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['C06.405.205.462', 'C06.405.469.326'], ['G02.111.263', 'G03.328'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of isoniazid preventive therapy on the evaluation of long-term effectiveness of infant MVA85A vaccination. | SETTING: South Africa.OBJECTIVE: To evaluate the long-term effectiveness of infant modified vaccinia Ankara virus-expressing antigen 85A (MVA85A) vaccination against tuberculosis (TB).DESIGN: We analysed data from a double-blind randomised placebo-controlled Phase 2b MVA85A infant TB vaccine trial (2009-2012), with ext... | ['Antitubercular Agents', 'Child, Preschool', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant', 'Isoniazid', 'Male', 'Poisson Distribution', 'South Africa', 'Survival Analysis', 'Treatment Outcome', 'Tuberculosis', 'Tuberculosis Vaccines', 'Vaccination'] | 28,633,702 | [['D27.505.954.122.085.255'], ['M01.060.406.448'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.59... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Failure of anti-hypertensive drugs to control blood pressure rise with isometric exercise in hypertension. | Isometric exercise causes a substantial rise in BP in normotensive and untreated hypertensives. The authors studied the isometric hand-grip test in 5 groups of treated hypertensives, namely beta-blockers, beta-blockers + diuretics, beta-blockers + diuretics + vasodilators, alpha-methyldopa alone and labetalol. All grou... | ['Adrenergic beta-Antagonists', 'Adult', 'Antihypertensive Agents', 'Blood Pressure', 'Diuretics', 'Drug Therapy, Combination', 'Female', 'Humans', 'Hypertension', 'Isometric Contraction', 'Labetalol', 'Male', 'Methyldopa', 'Middle Aged', 'Physical Exertion', 'Pulse', 'Vasodilator Agents'] | 6,120,507 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.696.560.500'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['G11.427.494.472'], ['D02.033.100.291.460', 'D02.065.793.324... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer. | Accumulating evidence demonstrates important roles for histone deacetylase in tumorigenesis (HDACs), highlighting them as attractive targets for antitumor drug development. Histone deactylase inhibitors (HDACIs), which have shown favorable anti-tumor activity with low toxicity in clinical investigations, are a promisin... | ['Anilides', 'Animals', 'Antineoplastic Agents', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cell Proliferation', 'Disease Models, Animal', 'Female', 'Histone Deacetylase Inhibitors', 'Histone Deacetylases', 'Humans', 'Hydroxamic Acids', 'Mice', 'Molecular Docking Simulation', 'Neoplasm Metastasis', 'Tumor Burden', 'Xenog... | 25,220,594 | [['D02.065.199', 'D02.092.146.113'], ['B01.050'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.389.360'], ['D08.811.277.087.520'], ['B01.050.150.900.649.313.988.400.11... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Simultaneous pressure and 19F NMR pH measurements of smooth muscle cells of intact hog carotid arteries at rest and during contractions with norepinephrine. | Using 19F NMR we have measured the intracellular pH of the vascular smooth muscle cells of hog carotid arteries at rest and during contractions induced with norepinephrine. Experiments were performed on single, intact arteries closed at both ends, superfused from the lumen and loaded with the 19F NMR pH indicator alpha... | ['Animals', 'Carotid Arteries', 'Fluorine', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Magnetic Resonance Spectroscopy', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Norepinephrine', 'Pressure', 'Reference Values', 'Swine'] | 3,172,972 | [['B01.050'], ['A07.015.114.186'], ['D01.268.380.300'], ['G02.300'], ['E05.481'], ['E05.196.867.519'], ['G11.427.494'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['G01.374.715'],... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ligament bracing--augmented primary suture repair in multiligamentous knee injuries]. | OBJECTIVE: Reconstruction of knee stability by primary ligament sutures and additional augmentation after knee dislocation.INDICATIONS: Acute knee dislocation Schenck type III and IV. Operative treatment should be performed within 7 days after injury.CONTRAINDICATIONS: Chronic instability after knee dislocation, refixa... | ['Adolescent', 'Adult', 'Braces', 'Equipment Failure Analysis', 'Female', 'Humans', 'Knee Dislocation', 'Knee Injuries', 'Ligaments, Articular', 'Male', 'Middle Aged', 'Multiple Trauma', 'Prosthesis Design', 'Suture Techniques', 'Treatment Outcome', 'Young Adult'] | 24,553,686 | [['M01.060.057'], ['M01.060.116'], ['E07.858.442.743.319'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518.500', 'C26.289.500', 'C26.558.554.500'], ['C26.558.554'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['M01.060.116.630'], ['C26.640'], ['E05.320.550', 'E07.695.680'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Laparoscopic versus open surgical exploration in premenopausal women with suspected acute appendicitis. | OBJECTIVES: To assess the utility of laparoscopic versus conventional surgical exploration in premenopausal women with suspected acute appendicitis.METHOD: Female patients aged 15-45 years in whom an independent decision to undertake surgical exploration had been made, were randomised to laparoscopic or open procedures... | ['Acute Disease', 'Adolescent', 'Adult', 'Appendectomy', 'Appendicitis', 'Female', 'Humans', 'Laparoscopy', 'Premenopause', 'Prospective Studies', 'Statistics, Nonparametric', 'Treatment Outcome'] | 14,768,141 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['E04.210.078'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['G08.686.157.500.812', 'G08.686.841.249.500.812'], ['E05.318.372.500.750.625', 'N05.715.360.33... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Aggregation of lipoprotein(a) to apolipoprotein A-I underlying HDL dysfunction as a major coronary risk factor. | OBJECTIVE: Dysfunction of high-density lipoprotein (HDL) may contribute to coronary heart disease (CHD) risk. We determined whether aggregation to lipoprotein (Lp)(a) of apolipoprotein (apo) A-I underlies HDL dysfunction conferring incident CHD risk.METHODS: A representative sample of 1509 middle-aged Turkish adults wa... | ['Aged', 'Apolipoprotein A-I', 'Coronary Artery Disease', 'Female', 'Follow-Up Studies', 'Humans', 'Hyperlipidemias', 'Incidence', 'Lipoprotein(a)', 'Male', 'Middle Aged', 'Regression Analysis', 'Risk Factors', 'Turkey'] | 23,835,300 | [['M01.060.116.100'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.45... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glucuronides in mussel Mytilus galloprovincialis as a possible biomonitor of environmental carcinogens. | 1. The in vitro incubation of mussel digestive gland with 1 mM aminofluorene resulted in the formation of glucuronides that (a) became mutagenic with carp liver S9, and (b) liberated S9-dependent mutagenic aglucones after beta-glucuronidase treatment. 2. Natural populations of mussels from unpolluted and polluted sites... | ['Animals', 'Bivalvia', 'Carcinogens, Environmental', 'Environmental Monitoring', 'Glucuronates', 'Glucuronidase', 'Mutagenicity Tests'] | 2,565,191 | [['B01.050'], ['B01.050.500.644.080'], ['D27.888.569.100.125'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.241.081.844.915.162', 'D02.241.152.811.162', 'D02.241.511.902.915.162', 'D09.811.922.162'], ['D08.811.277.450.426'], ['E05.393.560', 'E05.940.560']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
No Impact of Calorie or Unit Information on Ad Libitum Alcohol Consumption. | Aims: To investigate the impact of unit and calorie information on drinking behaviour in an ad libitum taste test paradigm.Methods: In this experimental human laboratory study, participants were randomized to one of four conditions, balanced by gender, using a 2 (unit information: present vs. absent) ? 2 (calorie infor... | ['Affect', 'Alcohol Drinking', 'Alcoholic Beverages', 'Alcoholic Intoxication', 'Beer', 'Consumer Health Information', 'Craving', 'Energy Intake', 'Female', 'Humans', 'Male', 'Motivation', 'Product Labeling', 'Students', 'Surveys and Questionnaires', 'Taste', 'Universities', 'Young Adult'] | 29,016,721 | [['F01.470.047'], ['F01.145.317.269'], ['G07.203.100.100', 'J02.200.100'], ['C25.775.100.175', 'F03.900.100.300'], ['G07.203.100.100.200', 'G07.203.200.250', 'J02.200.100.200', 'J02.350.250'], ['I02.233.332.186', 'N02.421.726.407.229'], ['F01.658.293.195'], ['G07.203.650.240.340'], ['B01.050.150.900.649.313.988.400.112... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
The effect of an acetic acid dip on carcass appearance, microbiological quality, and cooked breast meat texture and flavor. | In Experiment 1, broiler carcasses were subjected to a 10-min prechill treatment with and without a food grade vinegar at a concentration of .6% acetic acid. After treatment the carcasses were monitored for visual appearance and microbiological quality. Color change and skin appearance were subjectively monitored. Micr... | ['Acetates', 'Acetic Acid', 'Animals', 'Chickens', 'Color', 'Evaluation Studies as Topic', 'Food Handling', 'Food Microbiology', 'Meat'] | 8,202,437 | [['D02.241.081.018', 'D10.251.400.045'], ['D02.241.081.018.165', 'D10.251.400.045.500'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G01.590.540.199'], ['E05.337', 'N05.715.360.335'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Test-retest reliability and factor stability of the behavioral evaluation for epidemiology studies test battery. | The Behavioral Evaluation for Epidemiology Studies test battery uses touch-screen technology and novel methodologies to enhance neurobehavioral assessment. Scores generally show differential stability from the first trial with individual test reliabilities at or above .80 when normalized to a 3-min. administration. Six... | ['Adult', 'Brain Diseases', 'Computer Terminals', 'Diagnosis, Computer-Assisted', 'Environmental Exposure', 'Epidemiologic Studies', 'Humans', 'Male', 'Mass Screening', 'Microcomputers', 'Middle Aged', 'Neuropsychological Tests', 'Occupational Diseases', 'Occupational Exposure', 'Psychometrics', 'Reference Values', 'Re... | 12,509,185 | [['M01.060.116'], ['C10.228.140'], ['L01.224.230.260.115.500'], ['E01.158', 'L01.313.500.750.100.158'], ['N06.850.460.350'], ['E05.318.372.500', 'N05.715.360.330.500', 'N06.850.520.450.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.... | ['Named Groups [M]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Poor preoperative left ventricular function is associated with decreased insulin sensitivity during cardiac surgery. | OBJECTIVE: To investigate the association between preoperative left ventricular ejection function (LVEF) and whole-body insulin sensitivity during cardiac surgery.DESIGN: A prospective, non-randomized trial.SETTING: A tertiary care hospital setting.PARTICIPANTS: Patients undergoing elective cardiac surgery.INTERVENTION... | ['Aged', 'Blood Glucose', 'Cardiac Surgical Procedures', 'Cardiopulmonary Bypass', 'Female', 'Glucose Clamp Technique', 'Humans', 'Insulin Resistance', 'Male', 'Middle Aged', 'Preoperative Period', 'Prospective Studies', 'Ventricular Function, Left'] | 24,917,058 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E04.100.376', 'E04.928.220'], ['E04.292.413'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['M01.060.116.630'], ['E04.614.937', 'N02.421.585.753.93... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Modelling and estimation of multicomponent T(2) distributions. | Estimation of multiple T2 components within single imaging voxels typically proceeds in one of two ways; a nonparametric grid approximation to a continuous distribution is made and a regularized nonnegative least squares algorithm is employed to perform the parameter estimation, or a parametric multicomponent model is ... | ['Algorithms', 'Animals', 'Bayes Theorem', 'Brain', 'Least-Squares Analysis', 'Magnetic Resonance Imaging', 'Mice', 'Models, Statistical', 'Optic Nerve', 'Signal Processing, Computer-Assisted', 'Signal-To-Noise Ratio'] | 23,629,849 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['A08.186.211'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.318.740.500', 'E05.599.835'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Induction of Mouse Peritoneum Mesenchymal Stem Cells into Germ Cell-Like Cells Using Follicular Fluid and Cumulus Cells-Conditioned Media. | The peritoneum mesothelium lines body cavities and has the same origin as ovarian surface epithelium with probable existence of peritoneum mesenchymal stem cells (PMSCs). In the present research, PMSCs were isolated from peritoneum and differentiated into ovarian cell-like cells using human follicular fluid (HFF) and h... | ['Adipocytes', 'Animals', 'Cell Differentiation', 'Cell Transdifferentiation', 'Cells, Cultured', 'Culture Media, Conditioned', 'Cumulus Cells', 'Female', 'Follicular Fluid', 'Germ Cells', 'Humans', 'Mesenchymal Stem Cells', 'Mice', 'Oocytes', 'Osteocytes', 'Peritoneum'] | 30,767,610 | [['A11.329.114'], ['B01.050'], ['G04.152'], ['G04.356'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['A05.360.319.114.630.535.200.500', 'A06.300.312.497.535.300.500', 'A11.382.812.500', 'A11.436.329.500'], ['A05.360.319.114.630.535.150', 'A06.300.312.497.535.150', 'A12.207.270.340'], ['A05.360.490', 'A11.497'... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Partial trisomy of the long arm of the chromosme 11 by malsegregation of a maternal translocation t(11;22)(q23 1;q1 11)]. | A case of partial trisomy for the long arm of chromosome 11 due to malsegregation of a balanced maternal translocation is reported. | ['Chromosome Aberrations', 'Chromosomes, Human, 6-12 and X', 'Dermatoglyphics', 'Female', 'Humans', 'Infant', 'Psychomotor Disorders', 'Translocation, Genetic', 'Trisomy'] | 1,085,603 | [['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.325', 'G05.360.162.520.300.325'], ['E05.318.740.225.500.375', 'I01.198.780.937.343', 'N04.452.910.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C10.597.606.881', 'C23.888.592.604.882', 'F01.700.875'], ['C23.550.210.870', 'G05.36... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Expression patterns of parathyroid hormone-related peptide (PTHrP) and parathyroid hormone receptor type 1 (PTHR1) during human development are suggestive of roles specific for each gene that are not mediated through the PTHrP/PTHR1 paracrine signaling pathway. | Close temporal and spatial relationships between Pthrp and Pthr1 gene expression are reported during fetal life in rats, suggestive of a developmental role via a paracrine signaling pathway. In agreement, disruption of this signaling pathway is associated with developmental defects, as documented in mice and humans. Su... | ['Gene Expression Profiling', 'Humans', 'Mesoderm', 'Paracrine Communication', 'Parathyroid Hormone-Related Protein', 'Peptide Hormones', 'RNA, Messenger', 'Receptor, Parathyroid Hormone, Type 1', 'Receptors, Parathyroid Hormone', 'Signal Transduction'] | 12,609,604 | [['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A16.504.660'], ['G04.085.600'], ['D06.472.699.591', 'D12.644.276.908', 'D12.644.548.588', 'D12.776.467.890', 'D23.529.890'], ['D06.472.699', 'D12.644.548'], ['D13.444.735.544'], ['D12.776.543.750.695.650.100', 'D12.776.543.750.750.600.100'], ['D12.776... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High levels of urinary leukotriene E4 excretion in steroid treated patients with severe asthma. | Urinary LTE4 reflects the whole body production of the cysteinyl-leukotrienes (LTC4, LTD4 and LTE4) that are established mediators in asthma. The influence of chronic inhaled and oral glucocorticoid treatment on urinary excretion of leukotriene (LT) E4 was investigated in subjects with asthma. Enzyme immunoassay analys... | ['Administration, Oral', 'Adult', 'Aged', 'Asthma', 'Chronic Disease', 'Female', 'Follow-Up Studies', 'Forced Expiratory Volume', 'Humans', 'Leukotriene E4', 'Male', 'Middle Aged', 'Steroids'] | 14,635,978 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C23.550.291.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bilateral renal artery thrombotic occlusion: a unique complication following removal of a transthoracic intraaortic balloon. | An intraaortic balloon pump (IABP) was inserted through the ascending aorta during a coronary artery bypass operation. Five days later, after removal of the IABP and ligation of the end-to-side Dacron graft, the patient became acutely anuric. Abdominal aortography demonstrated a large "trapeze-shaped" thrombus which oc... | ['Aged', 'Assisted Circulation', 'Humans', 'Intra-Aortic Balloon Pumping', 'Male', 'Postoperative Complications', 'Radiography', 'Renal Artery Obstruction', 'Thrombosis'] | 7,092,390 | [['M01.060.116.100'], ['E04.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.050.215.400'], ['C23.550.767'], ['E01.370.350.700'], ['C12.777.419.775', 'C13.351.968.419.775', 'C14.907.137.727'], ['C14.907.355.830']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Oxidizing agents in hair cosmetic products and methods of their identification and determination]. | Hydrogen peroxide and oxidazing agents are used in hair lightening products, in oxidants of permanent wave products, hair dyeing products and toothpastes. In accordance with the Cosmetic Directive of the European Union (Council Directive of 27 July 1976 r. Annex III p. 12) maximum permitted concentration in the finishe... | ['Europe', 'Hair Preparations', 'Health Promotion', 'Humans', 'Oxidants'] | 10,846,940 | [['Z01.542'], ['D27.720.269.430'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.642', 'D27.888.569.540']] | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Bilocal visual noise as a probe of wide field motion computation. | Using an apparent visual motion stimulus with motion energies limited to specific separations in space and time, we study the computational structure of wide-field motion sensitive neurons in the fly visual brain. There is ample experimental evidence for correlation-based motion computation in many biological systems, ... | ['Animals', 'Diptera', 'Models, Animal', 'Motion', 'Motion Perception', 'Noise', 'Photic Stimulation', 'Psychophysics'] | 27,177,388 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750'], ['E05.598'], ['G01.482'], ['F02.463.593.932.567'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['E05.723.729'], ['E01.370.685', 'F04.096.753']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Linkage disequilibrium]. | The linkage disequilibrium which measures the association between linked genes is a temporary phenomenon in a population because of crossing over. But such associations persist in HLA system. These persistent linkage disequilibria may be due to the very small fraction of recombinaison between the loci but other explana... | ['Female', 'Genetic Linkage', 'Genetics, Medical', 'Genetics, Population', 'Humans', 'Male', 'Mathematics', 'Models, Genetic'] | 7,463,010 | [['G05.348'], ['H01.158.273.343.385.500', 'H02.403.350'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['E05.599.395.397']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid-freezing transmural cardiac biopsy drill. | We have built a transmural cardiac biopsy drill that uses an air turbine (10,000 rpm) to turn a stainless steel bore of either 2.0 or 4.5 mm diam. Vacuum draws the cut biopsies through the drill into isopentane chilled to -150 degrees C with liquid nitrogen. The steel bores cut through the beating canine left ventricul... | ['Animals', 'Biopsy, Needle', 'Coronary Circulation', 'Dogs', 'Freezing', 'Heart Diseases', 'Myocardium'] | 7,457,616 | [['B01.050'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relative lengths of fingers and toes in human males and females. | Digital scans of the hands and feet were obtained from 62 heterosexual females and 60 heterosexual males. Scans only of the hands were obtained from 29 homosexual females and 35 homosexual males. The lengths of the individual fingers and toes were estimated from those images by two experienced judges, and length ratios... | ['Adult', 'Androgens', 'Anthropometry', 'Female', 'Fingers', 'Functional Laterality', 'Homosexuality, Female', 'Homosexuality, Male', 'Humans', 'Male', 'Orientation', 'Otoacoustic Emissions, Spontaneous', 'Pattern Recognition, Visual', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Problem Solving', 'Reference Valu... | 12,488,115 | [['M01.060.116'], ['D27.505.696.399.472.161'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['A01.378.800.667.430'], ['F02.830.297.425', 'G11.561.225.425'], ['F01.145.802.975.500.400', 'G08.686.867.500.400'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Relief effect of CT-guided (125)I seed implantation on patients with spinal and paraspinal osteolytic metastatic tumors]. | Objective: To evaluate the clinical value of computed tomography (CT)-guided (125)I seed implantation in the treatment of patients with spinal and/or paraspinal osteolytic metastatic tumors. Methods: The radiation dose distribution was planned for 27 patients with 35 spinal and paraspinal osteolytic metastatic tumors b... | ['Brachytherapy', 'Cancer Pain', 'Female', 'Humans', 'Iodine Radioisotopes', 'Karnofsky Performance Status', 'Lymphatic Metastasis', 'Male', 'Osteolysis', 'Pain Measurement', 'Radiotherapy Dosage', 'Radiotherapy, Image-Guided', 'Spinal Neoplasms', 'Survival Rate', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 28,316,224 | [['E02.815.150'], ['C23.888.592.612.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E05.318.308.980.438.475.456.500.500', 'N05.715.360.300.800.438.375.364.500.500', 'N06.850.520.308.980.438.475.364.500.500'], ['C04.697.650.560', 'C23.550.727.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors. | During brain development, neural progenitor cells extend across the thickening brain wall and undergo mitosis. To understand how these two completely different cellular events are coordinated, we focused on the transcription pattern of the nestin gene (Nes), which encodes an intermediate filament protein strongly expre... | ['Animals', 'Cell Cycle', 'Electrophoretic Mobility Shift Assay', 'Embryonic Stem Cells', 'Female', 'Intermediate Filament Proteins', 'Mice', 'Mice, Transgenic', 'Nerve Tissue Proteins', 'Nervous System', 'Nestin', 'Pregnancy'] | 18,349,072 | [['B01.050'], ['G04.144'], ['E05.196.401.500'], ['A11.872.700.250'], ['D05.750.078.593', 'D12.776.220.475'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['D12.776.631'], ['A08'], ['D05.750.078.593.540', 'D12.776.220.475.540', 'D12.776.631.607'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationship between entry into child welfare and mental health service use. | OBJECTIVE: This study examined the relationship between initiation of outpatient mental health service use and level of child welfare involvement.METHODS: Three levels of child welfare involvement were examined: in-home care and no child welfare services beyond an initial investigation, in-home care and additional chil... | ['Adolescent', 'Child', 'Child Welfare', 'Child, Preschool', 'Cohort Studies', 'Female', 'Humans', 'Interviews as Topic', 'Male', 'Mental Health Services', 'Multivariate Analysis', 'Outpatients', 'United States'] | 16,088,016 | [['M01.060.057'], ['M01.060.406'], ['I01.880.787.293'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F04.408', 'N02.421.461'], [... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Absence of immunoreactive vasoactive intestinal polypeptide in tissue from the lungs of patients with asthma. | Vasoactive intestinal polypeptide (VIP) is a neuropeptide present in the nerve fibers of normal lungs, where it acts to relax bronchial smooth muscle. To determine its presence or absence in the lungs of patients with asthma, we examined lung tissue obtained at autopsy or lobectomy from five patients with asthma and ni... | ['Adolescent', 'Adult', 'Asthma', 'Humans', 'Immunohistochemistry', 'Lung', 'Middle Aged', 'Vasoactive Intestinal Peptide'] | 2,610,738 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.51... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Roentgenographically occult bronchogenic carcinoma of non-polypoid type: histological patterns of longitudinal growth within the bronchus. | Microscopy of the serial block-sections of the entire bronchial tree of all the resected specimens of roentgenographically occult bronchogenic carcinoma revealed new findings with respect to the histological patterns of longitudinal growth within the bronchial wall. Twenty-seven lesions which were non-polypoid on gross... | ['Bronchi', 'Carcinoma, Bronchogenic', 'Humans', 'Lung Neoplasms', 'Neoplasm Invasiveness', 'Radiography'] | 3,376,100 | [['A04.411.125'], ['C04.588.894.797.520.109.220', 'C08.381.540.140', 'C08.785.520.100.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.645', 'C23.550.727.645'], ['E01.370.350.700']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The kinetic studies on the intramolecular SH, S-S exchange reaction of bovine mercaptalbumin. | Bovine mercaptalbumin (BMA) has 17 disulfide bonds and one SH group at Cys-34 which catalyzes the intramolecular SH, S-S exchange reaction (N-A isomerization, molecular aging) in the alkaline region at low ionic strength, resulting in the formation of the aged form (A-form). The aging reaction was completely reversible... | ['Animals', 'Cattle', 'Disulfides', 'Fatty Acids', 'Hot Temperature', 'Isomerism', 'Osmolar Concentration', 'Serum Albumin', 'Serum Albumin, Bovine', 'Sulfhydryl Compounds'] | 8,155,715 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D10.251'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.111.570.685', 'G02.607.445'], ['G02.64... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block. | The role of electrical heterogeneity in development of cardiac arrhythmias is well recognized. The extent to which transmembrane action potential (TAP) heterogeneity contributes to the normal electrophysiology of well-oxygenated atria is not well defined. The principal objective of the present study was to define regio... | ['Action Potentials', 'Animals', 'Arrhythmias, Cardiac', 'Atrial Function, Right', 'Delayed Rectifier Potassium Channels', 'Dogs', 'Heart', 'Heart Atria', 'In Vitro Techniques', 'Perfusion', 'Potassium Channels', 'Potassium Channels, Voltage-Gated'] | 15,148,061 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['C14.280.067', 'C23.550.073'], ['G09.330.040.200'], ['D12.776.157.530.400.600.900.124', 'D12.776.543.550.450.750.900.124', 'D12.776.543.585.400.750.900.124'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['A07.541.358'], ['E05.481'], ['E... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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