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Situs Inversus Totalis: Single-Stage Anatomic Repair of Complex Congenital Heart Disease. | Transposition of the great arteries occurs rarely in patients with mirror image dextrocardia and situs inversus, while the combination with severe coarctation of the descending aorta (CoA) makes the anatomy even more unusual. Therefore, it is not surprising that a case with such unusual and complicated anatomy presents... | ['Abnormalities, Multiple', 'Aortic Coarctation', 'Humans', 'Infant, Newborn', 'Male', 'Situs Inversus', 'Transposition of Great Vessels'] | 27,881,809 | [['C16.131.077'], ['C14.240.400.090', 'C14.280.400.090', 'C16.131.240.400.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.131.810'], ['C14.240.400.915', 'C14.280.400.915', 'C16.131.240.400.915']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reversible in vitro packing of nucleosomal filaments into globular supranucleosomal units in chromatin of whole chick erythrocyte nuclei. | Structural transitions between extended and condensed forms of chromatin have been studied by electron microscopy of whole chicken erythrocyte nuclei incubated in low buffer concentrations (0.5 mM sodium borate; 1 to 5 mM Tris-HCl) with and without additions of monovalent or divalent cations. Both spread preparations a... | ['Animals', 'Calcium Chloride', 'Cell Nucleus', 'Chickens', 'Chromatin', 'DNA', 'Erythrocytes', 'Magnesium', 'Microscopy, Electron', 'Nucleosomes', 'Protein Conformation'] | 7,460,964 | [['B01.050'], ['D01.146.300', 'D01.210.450.150.150'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tuberculosis inequalities and socio-economic deprivation in Portugal. | OBJECTIVE: To analyse the geographical distribution of tuberculosis (TB) in Portugal and estimate the association between TB and socio-economic deprivation.METHODS: An ecological study at the municipality level using TB notifications for 2010-2014 was conducted. Spatial Bayesian models were used to calculate smoothed s... | ['Adult', 'Aged', 'Bayes Theorem', 'Disease Notification', 'Female', 'Health Status Disparities', 'Humans', 'Male', 'Middle Aged', 'Portugal', 'Poverty', 'Risk', 'Socioeconomic Factors', 'Spatial Analysis', 'Tuberculosis', 'Unemployment'] | 28,633,703 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.318.362', 'N06.850.520.373', 'N06.850.780.200.262'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Seroprevalence and social determinants of varicella in Turkey. | Background: In Turkey, varicella vaccine was introduced into routine childhood immunization in 2013, with a single dose administered to children aged 12 months. However, there is limited information on the morbidity (incidence and seroprevalence), mortality and burden of disease of varicella in the overall Turkish popu... | ['Chickenpox', 'Child', 'Child, Preschool', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Male', 'Seroepidemiologic Studies', 'Social Determinants of Health', 'Turkey'] | 29,908,025 | [['C01.925.256.466.930.250'], ['M01.060.406'], ['M01.060.406.448'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.950', 'N05.715.360.330.500.950', 'N06.850.520.450.500.950'], ['N01.2... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Risk, antepartum care, and outcome: impact of a maternity and infant care project. | A Title V Maternity and Infant Care (M&I) Project has been operating from Cleveland Metropolitan General Hospital for more than 13 years. To evaluate the effectiveness of its program of antepartum care, social and medical-obstetric risk factors and perinatal outcome were evaluated for pregnant women delivered during a ... | ['Female', 'Fetal Death', 'Fetal Viability', 'Health Facilities', 'Hospital Bed Capacity, 500 and over', 'Hospitals, Municipal', 'Humans', 'Maternal-Child Health Centers', 'Obstetric Labor, Premature', 'Ohio', 'Outcome and Process Assessment, Health Care', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Care', 'Risk'... | 7,393,502 | [['C13.703.223', 'C23.550.260.585'], ['G07.280', 'G07.345.500.325.235.875', 'G08.686.220'], ['N02.278'], ['N02.278.306.472.300'], ['N02.278.421.510.210', 'N02.278.421.660.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.035.310'], ['C13.703.420.491'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.54... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Relationship of Neisseria elongata subsp. Glycolytica to other members of the family Neisseriaceae. | Neisseria elongata subsp. glycolytica strain 6171/75 is closely similar to the type strain of N. elongata, M2, as regards DNA base composition, fatty acid content and electrophoretic mobility of two glutamate dehydrogenases, one of which showed a reaction of identity with the corresponding enzyme from M2 in double immu... | ['Clone Cells', 'DNA, Bacterial', 'Drug Resistance, Microbial', 'Glucose', 'Glutamate Dehydrogenase', 'Neisseriaceae', 'Streptomycin', 'Transformation, Genetic'] | 842,351 | [['A11.251.353'], ['D13.444.308.212'], ['G06.225', 'G07.690.773.984.269'], ['D09.947.875.359.448'], ['D08.811.682.664.500.398'], ['B03.440.400.425.550', 'B03.660.075.525'], ['D09.408.051.885'], ['G05.728.865']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigation of risk factors for mortality in aged guide dogs: A retrospective cohort study. | The overall median lifespan of domestic dogs has been estimated to 9-12 years, but little is known about risk factors for mortality in aged and a priori healthy dogs. The objective of this retrospective cohort study was to determine which characteristics are associated with mortality in aged and a priori healthy guide ... | ['Animals', 'Cause of Death', 'Cohort Studies', 'Dog Diseases', 'Dogs', 'Female', 'Life Tables', 'Longevity', 'Male', 'Pets', 'Retrospective Studies', 'Risk Factors', 'Skin Diseases', 'Species Specificity'] | 27,616,361 | [['B01.050'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.308.985.475', 'E05.318.740.100.500', 'N01.224... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Capillary electrochromatography of three â2-agonists in human urine using a lauryl methacrylate-based monolithic column. | A new method of online concentration capillary electrochromatography using a lauryl methacrylate-based monolithic column was developed for determination of three â(2)-agonists including salbutamol, procaterol, and formoterol. The separation parameters including acetonitrile concentration, running buffer pH, and concent... | ['Adrenergic beta-2 Receptor Agonists', 'Albuterol', 'Capillary Electrochromatography', 'Ethanolamines', 'Formoterol Fumarate', 'Humans', 'Procaterol'] | 22,689,490 | [['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['E05.196.181.400.150', 'E05.196.401.190.249', 'E05.301.300.190.500'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D02.033.100.291.425', 'D02.092.063.291.425']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Therapeutic use of topical corticosteroids in the vesiculobullous lesions of incontinentia pigmenti. | Incontinentia pigmenti (IP) is a rare genodermatosis caused by a mutation of nuclear factor kappa B essential modulator gene. There is no specific treatment for IP, therefore it has been claimed that there is no effective treatment to hasten resolution of any of the phases of IP. However, the initial vesiculobullous st... | ['Administration, Cutaneous', 'Chlorquinaldol', 'Diflucortolone', 'Female', 'Glucocorticoids', 'Humans', 'Incontinentia Pigmenti', 'Infant, Newborn'] | 19,489,863 | [['E02.319.267.120.060'], ['D03.633.100.810.350.625.250.260'], ['D04.210.500.745.432.719.320.250', 'D04.210.500.908.405.250'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.131.077.445', 'C16.131.831.580', 'C16.320.850.420', 'C17.800.621.497', 'C17.800.804.580', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prognostic factors following liver resection for hepatic metastases from colorectal cancer. | BACKGROUND/AIMS: We aimed to identify prognostic factors that may allow better patient selection for liver resection for colorectal liver metastases.METHODOLOGY: A retrospective analysis of the files of 120 patients undergoing liver resection for colorectal metastases between 9/85 and 12/96 was performed. Survival and ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Female', 'Hepatectomy', 'Humans', 'Likelihood Functions', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Patient Selection', 'Prognosis', 'Proportional Hazards Models', 'Retrospective Studies', 'Survival Rate', 'Treatment Outcome'] | 10,690,615 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.36... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reduction of field of view in MRI using a surface-spoiling local gradient insert. | Herein is presented a method for suppressing the magnetic resonance signal to a controlled depth by applying a spatially heterogeneous spoiler field between the slice-select and readout pulses. Eliminating the signal from near-surface regions allows one to shrink the field of view without introducing aliasing artifacts... | ['Artifacts', 'Heart', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Phantoms, Imaging'] | 9,702,901 | [['E05.047'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['E07.671']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Liver damage detected after a hepatectomy for liver metastasis after 12 courses of mFOLFOX6 therapy as an adjuvant chemotherapy for colorectal cancer]. | The FOLFOX regimen is approved as an adjuvant therapy for colon cancer in Japan. We report a case of pathological damage in the resected non-cancerous liver after 12 courses of mFOLFOX6 therapy as an adjuvant therapy for stage IIIb colon cancer. A 45-year-old man underwent laparoscopic right hemicolectomy for ascending... | ['Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis', 'Chemical and Drug Induced Liver Injury', 'Chemotherapy, Adjuvant', 'Colonic Neoplasms', 'Fluorouracil', 'Hepatectomy', 'Humans', 'Leucovorin', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Organoplatinum Compounds'] | 23,268,030 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G04.146.954.035'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['E02.186.170', 'E02.319.170'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D03.383.742.698.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The history of behavioral neurology. | Although often considered to be a relatively new subdivision of neurology, behavioral studies actually have a long and colorful history. The events that led originally to a consideration of behavior as a neurologic subspecialty are outlined, followed by a listing of some of the major occurrences and key figures that ha... | ['Behavioral Sciences', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'History, Ancient', 'Neurology'] | 8,441,365 | [['F04.096'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.470'], ['H02.403.600']] | ['Psychiatry and Psychology [F]', 'Humanities [K]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural analysis of the 5' region of mouse and human Huntington disease genes reveals conservation of putative promoter region and di- and trinucleotide polymorphisms. | We have previously cloned and characterized the murine homologue of the Huntington disease (HD) gene and shown that it maps to mouse chromosome 5 within a region of conserved synteny with human chromosome 4p16.3. Here we present a detailed comparison of the sequence of the putative promoter and the organization of the ... | ['Animals', 'Base Sequence', 'Chromosomes, Human, Pair 4', 'Cloning, Molecular', 'Conserved Sequence', 'DNA', 'DNA, Satellite', 'Exons', 'Humans', 'Huntington Disease', 'Introns', 'Mice', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'Nucleotides', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'Repetitive ... | 7,759,106 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.520.300.280.285', 'G05.360.162.520.300.280.285'], ['E05.393.220'], ['G02.111.570.580'], ['D13.444.308'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.15... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Analysis of some immunological parameters in pulmonary tuberculosis]. | The role of humoral response in immunity to tuberculosis (TB) is unclear, and clinical studies have yield inconsistent conclusions. The aim of this study was to evaluate number of the lymphocytes B, concentrations of immunoglobulins A, G, M (IgA, IgG, IgM), circulating immune complexes (KI), components C3 and C4 of com... | ['Adult', 'Aged', 'Antigen-Antibody Complex', 'Antitubercular Agents', 'B-Lymphocytes', 'Biomarkers', 'Complement C3', 'Complement C4', 'Female', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Macrophage-1 Antigen', 'Male', 'Middle Aged', 'Monocytes', 'Receptors, Fc', 'Time Factors', 'Tuberculos... | 15,176,294 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D27.505.954.122.085.255'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D23.101'], ['D12.77... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cost-effectiveness Analysis of Sacubitril/Valsartan vs Enalapril in Patients With Heart Failure and Reduced Ejection Fraction. | IMPORTANCE: The angiotensin receptor neprilysin inhibitor sacubitril/valsartan was associated with a reduction in cardiovascular mortality, all-cause mortality, and hospitalizations compared with enalapril. Sacubitril/valsartan has been approved for use in heart failure (HF) with reduced ejection fraction in the United... | ['Aminobutyrates', 'Angiotensin Receptor Antagonists', 'Angiotensin-Converting Enzyme Inhibitors', 'Cost-Benefit Analysis', 'Drug Combinations', 'Enalapril', 'Female', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Stroke Volume', 'Tetrazoles', 'Valsartan'] | 27,438,344 | [['D02.241.081.114.500', 'D12.125.190'], ['D27.505.519.162'], ['D27.505.519.389.745.085'], ['N03.219.151.125'], ['D26.310'], ['D12.644.456.345.360'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E01.370.370.380.150.70... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. | A peripheral mononeuropathy was produced in adult rats by placing loosely constrictive ligatures around the common sciatic nerve. The postoperative behavior of these rats indicated that hyperalgesia, allodynia and, possibly, spontaneous pain (or dysesthesia) were produced. Hyperalgesic responses to noxious radiant heat... | ['Animals', 'Behavior, Animal', 'Cold Temperature', 'Hot Temperature', 'Hyperalgesia', 'Hyperesthesia', 'Ligation', 'Male', 'Neurons, Afferent', 'Pain', 'Peripheral Nervous System Diseases', 'Rats', 'Rats, Inbred Strains', 'Reaction Time', 'Sciatic Nerve', 'Skin', 'Time Factors'] | 2,837,713 | [['B01.050'], ['F01.145.113'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['C10.597.751.7... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
HLA-C Single Nucleotide Polymorphism Associated with Increased Viral Load Level in HIV-1 Infected Individuals from Northeast Brazil. | BACKGROUND: Genetic variations in Human leukocyte antigen C (HLA-C), Zinc ribbon domain containing 1 (ZNRD1) and its antisense RNA (ZNRD1-AS1) genes are known to influence the HIV-1 replication and disease progression.OBJECTIVE AND METHOD: We evaluated the distribution of HLA-C (rs10484554, rs9264942) and ZNRD1 (rs8321... | ['Adolescent', 'Adult', 'Brazil', 'CD4 Lymphocyte Count', 'DNA-Binding Proteins', 'Female', 'HIV Infections', 'HIV-1', 'HLA-C Antigens', 'Histocompatibility Antigens Class I', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Viral Load', 'Young Adult'] | 28,494,720 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.176'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['D12.776.260'], ['C01.221.250.875', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Kinetic simulation of enhanced biological phosphorus removal with fermentation broth as carbon source]. | As a high-quality carbon source, fermentation broth could promote the phosphorus removal efficiency in enhanced biological phosphorus removal (EBPR). The transformation of substrates in EBPR fed with fermentation broth was well simulated using the modified activated sludge model No. 2 (ASM2) based on the carbon source ... | ['Bacteria', 'Biodegradation, Environmental', 'Bioreactors', 'Carbon', 'Fermentation', 'Kinetics', 'Models, Theoretical', 'Phosphorus', 'Sewage', 'Waste Disposal, Fluid', 'Waste Water'] | 24,028,007 | [['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.115', 'J01.897.120.115'], ['D01.268.150'], ['G02.111.158.249', 'G03.191.249'], ['G01.374.661', 'G02.111.490'], ['E05.599'], ['D01.268.666'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.7... | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Self-supported chiral titanium cluster (SCTC) as a robust catalyst for the asymmetric cyanation of imines under batch and continuous flow at room temperature. | A robust heterogeneous self-supported chiral titanium cluster (SCTC) catalyst and its application in the enantioselective imine-cyanation/Strecker reaction is described under batch and continuous processes. One of the major hurdles in the asymmetric Strecker reaction is the lack of availability of efficient and reusabl... | ['Amino Alcohols', 'Benzhydryl Compounds', 'Catalysis', 'Imines', 'Nitriles', 'Temperature', 'Titanium'] | 22,438,070 | [['D02.033.100', 'D02.092.063'], ['D02.455.426.559.389.115'], ['G02.130'], ['D02.491'], ['D02.626'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Opposite effects of two thiazolidinediones, ciglitazone and troglitazone, on proteinase-activated receptor-1-triggered prostaglandin E(2) release. | Thiazolidinediones, known as peroxisome proliferator-activated receptor-gamma (PPARgamma) agonists, may modify prostaglandin formation and exert gastroprotective effects. Since activation of proteinase-activated receptor-1 (PAR1) reveals endogenous prostanoid-dependent gastroprotection, we investigated if two thiazolid... | ['Animals', 'Base Sequence', 'Cell Line', 'Chromans', 'DNA Primers', 'Dinoprostone', 'Gastric Mucosa', 'Phosphorylation', 'Polymerase Chain Reaction', 'Rats', 'Receptor, PAR-1', 'Signal Transduction', 'Thiazolidinediones', 'Troglitazone'] | 19,954,759 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['D03.383.663.283.240', 'D03.633.100.150.240'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['A03.556.875.875.440', 'A10.615.550.291'], ['G02.111.665'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reduction of asthenopia related to accommodative relaxation by means of far point stimuli. | PURPOSE: To conduct an experimental investigation of the effect of accommodative relaxation using far point shift stimuli for the reduction of asthenopia.METHODS: Twenty-two female students accommodated to a far point shift stimuli during a 2-min period immediately after a 15-min sustained task on a three-dimensional d... | ['Accommodation, Ocular', 'Adult', 'Asthenopia', 'Female', 'Generalization, Stimulus', 'Humans', 'Hyperopia', 'Myopia', 'Refraction, Ocular'] | 15,715,563 | [['G14.010'], ['M01.060.116'], ['C11.093'], ['F02.463.425.357.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.744.479'], ['C11.744.636'], ['E01.370.380.850.700', 'G01.590.775', 'G14.760']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Direct Observation of Ground-State Product Formation in a 1,3-Cyclohexadiene Ring-Opening Reaction. | Ultrafast photoelectron imaging using a 90 nm vacuum-UV probe pulse is applied to the ring-opening reaction of 1,3-cyclohexadiene (CHD) in the gas phase, and formation of 1,3,5-hexatriene (HT) and CHD in their electronic ground states is observed in real time. The analysis of the transient photoelectron kinetic energy ... | ['Cyclohexenes', 'Electrons', 'Gases', 'Models, Molecular', 'Molecular Conformation', 'Photoelectron Spectroscopy', 'Polyenes'] | 26,261,944 | [['D02.455.426.392.368.367.379'], ['G01.249.335', 'G01.358.500.750'], ['D01.362'], ['E05.599.595'], ['G02.111.570.820'], ['E05.196.867.618'], ['D02.455.326.271.665']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prospective capillaroscopy-based study on transition from primary to secondary Raynaud's phenomenon: preliminary results. | The objective of this prospective study was to investigate the transition from primary (PRP) to secondary (SRP) Raynaud's phenomenon (RP), in a large cohort of patients affected by isolated RP. A total of 2065 patients with RP were investigated by clinical interview, laboratory examinations, and nailfold videocapillaro... | ['Disease Progression', 'Humans', 'Microscopic Angioscopy', 'Middle Aged', 'Predictive Value of Tests', 'Prospective Studies', 'Raynaud Disease'] | 24,192,563 | [['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.277.500', 'E01.370.370.560', 'E05.595.185.500'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.75... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel sequential electrostatic-HILIC SPE within a quantitative method for bivalirudin in human plasma by LC-SRM. | AIM: This work set out to realize an idea for a novel means of extracting the peptide therapeutic bivalirudin from human plasma in what would be a uniquely selective means of SPE, a mixed-mode protocol involving electrostatic interactions followed by HILIC.RESULTS: Inter and intra-assay relative error ranged from 3.52 ... | ['Blood Chemical Analysis', 'Calibration', 'Chromatography, High Pressure Liquid', 'Hirudins', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Peptide Fragments', 'Recombinant Proteins', 'Solid Phase Extraction', 'Static Electricity', 'Tandem Mass Spectrometry'] | 27,678,052 | [['E01.370.225.124.100', 'E05.200.124.100'], ['E05.978.155'], ['E05.196.181.400.300'], ['D12.644.861.060.875', 'D12.776.872.060.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['D12.644.541'], ['D12.776.828'], ['E05.196.155.800'], ['G01.358.500.249.820'], ['E05.196.566.880']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incomplete removal of the RNA primer for minus-strand DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase. | A synthetic RNA oligonucleotide (15-mer) corresponding to the 3' end of the lysine tRNA primer was hybridized to single-stranded DNA containing the human immunodeficiency virus type 1 (HIV-1) primer-binding site and extended with a DNA polymerase. The resulting structures were used to study primer removal by the RNase ... | ['Base Sequence', 'DNA, Viral', 'HIV-1', 'Molecular Sequence Data', 'RNA, Transfer', 'RNA, Viral', 'RNA-Directed DNA Polymerase', 'Ribonucleotides', 'Templates, Genetic'] | 1,370,087 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.568'], ['B04.820.650.589.650.350.400'], ['L01.453.245.667'], ['D13.444.735.757'], ['D13.444.735.828'], ['D08.811.913.696.445.308.300.750', 'D12.776.964.775.375.750', 'D12.776.964.900.750.500.750', 'D12.776.964.970.600.850.375.750'], ['D13.695.827... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
BCN Checkpoint: same-day confirmation of reactive HIV rapid test with Point Of Care HIV-RNA accelerates linkage to care and reduces anxiety. | BACKGROUND: The introduction in 2006 of the rapid HIV test by BCN Checkpoint in a non-clinical setting has been a successful step forwards in the uptake of testing. Nevertheless, HIV serostatus should be reported as HIV positive only when a reactive result has been tested again using a different assay (WHO guidelines 2... | ['Anxiety', 'Diagnostic Services', 'Diagnostic Tests, Routine', 'HIV Infections', 'Humans', 'Immunoassay', 'Molecular Diagnostic Techniques', 'Point-of-Care Systems', 'Time Factors'] | 29,488,706 | [['F01.470.132'], ['N02.421.726.233'], ['E01.370.395'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['E01.370.225.880', 'E05.200.880', 'E05.393.520'], ['N04.45... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparing the removal of perchlorate when using single-walled carbon nanotubes (SWCNTs) or granular activated carbon: adsorption kinetics and thermodynamics. | This study aims to remove perchlorate using single-walled carbon nanotubes (SWCNTs) or granular activated carbon (GAC). Dynamic and equilibrium adsorption experiments were performed to evaluate the thermodynamic behavior of perchlorate on SWCNTs and GAC. Key parameters affecting the adsorption, such as pH, ionic streng... | ['Adsorption', 'Charcoal', 'Kinetics', 'Nanotubes, Carbon', 'Osmolar Concentration', 'Perchlorates', 'Temperature', 'Thermodynamics', 'Water Pollutants, Chemical', 'Water Purification'] | 24,410,681 | [['G01.030', 'G02.020'], ['D01.268.150.150'], ['G01.374.661', 'G02.111.490'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['G02.640'], ['D01.029.260.650', 'D01.210.675'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906'], ['D27.888.284.903.6... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[The significance of colposcopy in surgical gynecologic emergent situations]. | There has been described the case of coexistence of ruptured extra-uterine cysts and cancer of cervix uteri diagnosed by preliminary colposcopic examination confirmed by cytology and the directed biopsy specimen what enabled simultaneous surgical treatment. The presented paper is sufficient example that the colposcopy ... | ['Adult', 'Colposcopy', 'Female', 'Humans', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Pregnancy, Ectopic', 'Rupture, Spontaneous', 'Uterine Cervical Neoplasms'] | 1,304,508 | [['M01.060.116'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C04.850', 'C13.703.720'], ['C13.703.733'], ['C23.300.909'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A retrospective clinical audit of cervical smears reported as 'glandular neoplasia'. | The aims of this study were to review the diagnostic pathway of women with smears reported as 'glandular neoplasia' and to outline the management, colposcopy findings, treatment and final histological diagnosis in these women. The design was a retrospective review. A total of 114 women were identified over a 5-year per... | ['Cervical Intraepithelial Neoplasia', 'Clinical Laboratory Techniques', 'Female', 'Humans', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 15,324,445 | [['C04.557.470.200.240.250'], ['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.762.850', 'C13.351.937.418.875.850'], ['E01.370.225.500.384.100.800', 'E01.370.225.998.054.800', 'E01.370.378.900', 'E04.074.800', 'E05.200.5... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation and Characterization of Hypoglycemic Nanoparticles for Oral Insulin Delivery. | Polymeric nanoparticles have been widely investigated as insulin delivery systems for oral administration. However, the toxic nature of many artificial polymers hampers their effective application, creating a demand for the further exploration of alternative natural polymers. In addition, ethnobotanical research has re... | ['Administration, Oral', 'Animals', 'Antimicrobial Cationic Peptides', 'Cell Survival', 'Diabetes Mellitus, Experimental', 'Drug Carriers', 'Drug Delivery Systems', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Nanoparticles', 'Rats', 'Rats, Sprague-Dawley'] | 29,059,517 | [['E02.319.267.100'], ['B01.050'], ['D12.644.050', 'D12.776.543.695.054'], ['G04.346'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Variability in dissolution rates of cholesterol pellets in bile acid solutions. | Large variations in dissolution rate behavior of cholesterol monohydrate pellets may result from small changes in experimental procedures. For example, when cholesterol monohydrate pellets were stored overnight prior to a dissolution run, the initial dissolution rates varied by more than a factor of 2. It is well known... | ['Bile Acids and Salts', 'Cholesterol', 'Cholic Acids', 'Humidity', 'Kinetics', 'Light', 'Solubility', 'Temperature'] | 7,264,913 | [['D04.210.500.105'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.105.225', 'D04.210.500.221.430'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['G01.374.661', 'G02.111.490'], ['G01.358.500.505.650', 'G01.590.540', 'G01.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structural basis for polymerase ç-promoted resistance to the anticancer nucleoside analog cytarabine. | Cytarabine (AraC) is an essential chemotherapeutic for acute myeloid leukemia (AML) and resistance to this drug is a major cause of treatment failure. AraC is a nucleoside analog that differs from 2'-deoxycytidine only by the presence of an additional hydroxyl group at the C2' position of the 2'-deoxyribose. The active... | ['Antineoplastic Agents', 'Crystallization', 'Cytarabine', 'Cytidine', 'DNA Repair', 'DNA Replication', 'DNA-Directed DNA Polymerase', 'Deoxycytidine', 'Humans', 'Molecular Structure', 'X-Ray Diffraction'] | 30,140,014 | [['D27.505.954.248'], ['E05.196.300', 'G02.171'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['D03.383.742.680.245', 'D13.570.685.245', 'D13.570.800.286'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['D08.811.913.696.445.308.300'], ['D03.383.742.680.245.500', 'D13.570.230.329', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hormonal therapy after the operation for catamenial pneumothorax - is it always necessary? | BACKGROUND: Our recent clinical observations put into question the routine hormonal therapy for pneumothorax recurrence prevention, in patients operated for catamenial pneumothorax (CP).METHODS: Retrospective review of the treatment of four women operated for CP in a recent 32-months period.RESULTS: The four presented ... | ['Adult', 'Female', 'Gonadotropin-Releasing Hormone', 'Hormone Replacement Therapy', 'Humans', 'Middle Aged', 'Pneumothorax', 'Postoperative Period', 'Recurrence', 'Retrospective Studies', 'Thoracic Surgery, Video-Assisted'] | 27,079,920 | [['M01.060.116'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['E02.319.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C08.528.778'], ['E04.614.750', 'N02.421.585.753.750'], ['C23.550.291.937'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fractures of osteochondroma during physical exercise. | BACKGROUND: The mechanism responsible and the best form of treatment for fractures of osteochondromas remain unclear.PURPOSE: We studied the incidence, cause, treatment, and outcome of fractures of osteochondroma over a 17-year period.STUDY DESIGN: Retrospective cohort study.METHODS: We retrospectively reviewed all cas... | ['Adolescent', 'Adult', 'Athletic Injuries', 'Bone Neoplasms', 'Child', 'Female', 'Fractures, Bone', 'Humans', 'Incidence', 'Male', 'Osteochondroma', 'Radiography', 'Retrospective Studies', 'Treatment Outcome'] | 14,623,671 | [['M01.060.057'], ['M01.060.116'], ['C26.115'], ['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04.557.450.565.575.610', 'C05.116.099.708.67... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polyamines and Ca2+ mediate hyperosmolal opening of the blood-brain barrier: in vitro studies in isolated rat cerebral capillaries. | We recently presented evidence that the reversible opening of the blood-brain barrier (BBB) by the infusion of 1.6 M mannitol into the rat internal carotid artery is mediated by a rapid stimulation of ornithine decarboxylase (ODC) activity and putrescine synthesis in cerebral capillaries. We have now investigated this ... | ['Aminoisobutyric Acids', 'Animals', 'Biological Transport', 'Blood-Brain Barrier', 'Calcium', 'Capillaries', 'Cerebrovascular Circulation', 'Deoxyglucose', 'Female', 'Horseradish Peroxidase', 'In Vitro Techniques', 'Mannitol', 'Ornithine Decarboxylase', 'Osmolar Concentration', 'Polyamines', 'Rats', 'Tetradecanoylphor... | 2,494,298 | [['D02.241.081.114.968.249', 'D12.125.070.075', 'D12.125.190.055'], ['B01.050'], ['G03.143'], ['A07.035', 'A08.186.211.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A07.015.461.165'], ['G09.330.100.159'], ['D09.254.229'], ['D08.811.682.732.512'], ['E05.481'], ['D02.033.800.609', 'D09.853.609'], ['D08.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Influencing factors on start-up period in a bioaugmented membrane bioreactor using genetically engineered microorganism (GEM)]. | High and stable atrazine removal could be obtained after a start-up period in a membrane bioreactor (MBR) bioaugmented with genetically engineered microorganism (GEM) and the removal efficiency was above 90% . The shortest start-up period was 2 d and the longest one was 12 d under different conditions. Initial influent... | ['Atrazine', 'Bioreactors', 'Escherichia coli', 'Genetic Engineering', 'Herbicides', 'Membranes, Artificial', 'Soil Pollutants'] | 17,633,186 | [['D03.383.931.247'], ['E07.115', 'J01.897.120.115'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.393.420'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D27.888.284.756']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evidence for the involvement of dopamine in stress-induced suppression of reproduction in the cichlid fish Oreochromis mossambicus. | In the present study, we examined whether stress-induced suppression of reproduction is mediated through the catecholaminergic neurotransmitter dopamine (DA) in the female cichlid fish Oreochromis mossambicus. In the first experiment, application of antibody against tyrosine hydroxylase (TH; a marker for DA) in brain s... | ['Animals', 'Cichlids', 'Domperidone', 'Dopamine', 'Dopamine Antagonists', 'Female', 'Luteinizing Hormone', 'Ovary', 'Pituitary Gland', 'Preoptic Area', 'Reproduction', 'Stress, Physiological', 'Tyrosine 3-Monooxygenase'] | 25,712,855 | [['B01.050'], ['B01.050.150.900.493.602.200'], ['D03.383.621.210', 'D03.633.100.103.370'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Helping More Patients Receive a Living Donor Kidney Transplant. | The best treatment option for many patients with kidney failure is a kidney transplant from a living donor. Countries that successfully increase their rate of living kidney donation will decrease their reliance on dialysis, the most expensive and high-risk form of kidney replacement therapy. Outlined here are some barr... | ['Aged', 'Female', 'Health Services Accessibility', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Living Donors', 'Tissue and Organ Procurement', 'United States'] | 30,082,336 | [['M01.060.116.100'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.898.656'], ['N02.421.911'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Nurse educator performance standards. | In this article, the authors highlight the process by which one staff education department developed performance standards. These standards facilitate orientation of new educators, assist with the planning of developmental goals, and guide the evaluation process. This process can serve as a prototype for nurse educator... | ['Education, Nursing, Continuing', 'Employee Performance Appraisal', 'Faculty, Nursing', 'Guidelines as Topic', 'Humans', 'Job Description', 'Teaching'] | 8,954,402 | [['I02.358.212.450', 'I02.358.462.399'], ['N04.452.677.370'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.677.410'], ['I02.903']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Immunologic, virologic, and clinical consequences of episodes of transient viremia during suppressive combination antiretroviral therapy. | OBJECTIVE: To investigate immunologic, virologic, and clinical consequences of episodes of transient viremia in patients with sustained virologic suppression.METHODS: From the AIDS Therapy Evaluation Project, Netherlands cohort, 4447 previously therapy-naive patients were selected who were on continuous combination ant... | ['Anti-HIV Agents', 'Drug Therapy, Combination', 'HIV Infections', 'Humans', 'Viremia'] | 18,285,709 | [['D27.505.954.122.388.077.088'], ['E02.319.310'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.937', 'C23.550.470.790.500.900']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Erythrocyte insulin binding in a family with hereditary motor sensory neuropathy (Charcot-Marie-Tooth) with superimposed insulin-dependent type I diabetes mellitus. | Studies on erythrocyte insulin receptors were performed in a family with hereditary motor sensory neuropathy (Charcot-Marie-Tooth) with superimposed type I diabetes mellitus. The maximum specific insulin binding of the erythrocytes was high and the increase was shown to be due to increased affinity of the insulin recep... | ['Adolescent', 'Adult', 'Aged', 'C-Peptide', 'Charcot-Marie-Tooth Disease', 'Diabetes Mellitus, Type 1', 'Erythrocytes', 'Female', 'Humans', 'Insulin', 'Muscular Atrophy, Spinal', 'Receptor, Insulin', 'Reference Values'] | 2,667,841 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['A11.118.290', 'A11.443.240... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
High level of resistance to metronidazole and clarithromycin in Helicobacter pylori isolated from pediatric patients in Poland (1997-2001). | Resistance to metronidazole (Met), clarithromycin (Cla) and amoxycillin (Amo) was examined using H. pylori isolates from child patients before and after treatment in the period 1997-2001. The rate of Met and Cla resistance before treatment was 35.2 and 8.6%, respectively. Six weeks after treatment 48.4% of the isolated... | ['Adolescent', 'Amoxicillin', 'Anti-Bacterial Agents', 'Child', 'Clarithromycin', 'Drug Resistance, Multiple, Bacterial', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Metronidazole', 'Microbial Sensitivity Tests', 'Poland', 'Stomach'] | 15,227,783 | [['M01.060.057'], ['D02.065.589.099.750.750.050.050', 'D02.886.108.750.750.050.050', 'D03.633.100.300.750.750.050.050'], ['D27.505.954.122.085'], ['M01.060.406'], ['D02.540.576.500.992.100'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['C01.150.252.400.466'], ['B03... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The impact of subgroup type and subgroup configurational properties on work team performance. | Scholars have invoked subgroups in a number of theories related to teams, yet certain tensions in the literature remain unresolved. In this article, we address 2 of these tensions, both relating to how subgroups are configured in work teams: (a) whether teams perform better with a greater number of subgroups and (b) wh... | ['Cooperative Behavior', 'Decision Making', 'Food Industry', 'Group Processes', 'Humans', 'Interpersonal Relations', 'Organizational Innovation', 'Social Identification', 'Workplace'] | 23,915,429 | [['F01.145.813.115'], ['F02.463.785.373'], ['J01.576.423'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['N04.452.610'], ['F01.145.813.708'], ['N01.824.245.925', 'N04.452.677.975']] | ['Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancer. | BACKGROUND: Blockade of platelet activation and aggregation can inhibit metastasis in preclinical models and is associated with cancer prevention. To test whether disruption of platelet function with clopidogrel and aspirin would decrease the number of circulating tumor cells (CTCs) in patients with metastatic breast c... | ['Aspirin', 'Blood Platelets', 'Breast Neoplasms', 'Case-Control Studies', 'Clopidogrel', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplastic Cells, Circulating', 'Platelet Activation', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Progno... | 24,267,729 | [['D02.455.426.559.389.657.410.595.176'], ['A11.118.188', 'A15.145.229.188'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['E02.319.310'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An automated ocular microtremor feature extraction using the Gabor thresholding technique. | Ocular Microtremor (OMT) is a very fine continuous eye movement which has potential in monitoring and identifying a number of clinical conditions. There is a need for improved analysis and processing techniques to extract useful, quantifiable parameters from the OMT signal. A number of papers have shown the clinical si... | ['Algorithms', 'Artifacts', 'Eye Movements', 'Humans', 'Signal Processing, Computer-Assisted', 'Tremor'] | 18,002,589 | [['G17.035', 'L01.224.050'], ['E05.047'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.800'], ['C10.597.350.850', 'C23.888.592.350.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The outwardly rectifying chloride channel in rat peritoneal mast cells is regulated by serine/threonine kinases and phosphatases. | A slowly activating, outwardly rectifying Cl- channel (ORCC) has been described in rat peritoneal mast cells (RPMCs). This channel is activated by intracellular application of cAMP, an effect that might be mediated by a PKA-type serine/threonine protein kinase. To test this hypothesis, whole-cell patch-clamp experiment... | ['8-Bromo Cyclic Adenosine Monophosphate', 'Animals', 'Chloride Channels', 'Chlorides', 'Cyclic AMP-Dependent Protein Kinases', 'Enzyme Inhibitors', 'Male', 'Marine Toxins', 'Mast Cells', 'Membrane Potentials', 'Okadaic Acid', 'Oxazoles', 'Patch-Clamp Techniques', 'Peritoneal Cavity', 'Phosphoric Monoester Hydrolases',... | 11,907,822 | [['D03.633.100.759.646.138.395.225', 'D13.695.462.200.225', 'D13.695.667.138.395.225', 'D13.695.827.068.395.225'], ['B01.050'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A light-regulated host-guest-based nanochannel system inspired by channelrhodopsins protein. | The light-controlled gating of ion transport across membranes is central to nature (e.g., in protein channels). Herein, inspired by channelrhodopsins, we introduce a facile non-covalent approach towards light-responsive biomimetic channelrhodopsin nanochannels using host-guest interactions between a negative pillararen... | ['Azo Compounds', 'Channelrhodopsins', 'Ion Transport', 'Light', 'Ultraviolet Rays'] | 28,811,463 | [['D02.172'], ['D12.776.157.530.400.163', 'D12.776.543.550.450.163', 'D12.776.543.585.400.163', 'D12.776.765.593.250'], ['G03.143.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Glomerular thromboxane A2/prostaglandin H2 receptors: characterization and effect of adriamycin-induced nephrotic syndrome. | We have characterized the thromboxane (TX) A2/prostaglandin (PG) H2 receptor in glomeruli isolated from the rat using the agonist radioligand [125I]-BOP. Binding of [125I]-BOP was highly specific, stereoselective, and to a single class of high affinity binding sites (Kd = 1.16 +/- 0.22 nM and Bmax = 348 +/- 32 fmol/mg ... | ['Animals', 'Binding, Competitive', 'Bridged Bicyclo Compounds', 'Bridged Bicyclo Compounds, Heterocyclic', 'Doxorubicin', 'Fatty Acids, Unsaturated', 'Kidney Glomerulus', 'Kinetics', 'Male', 'Nephrotic Syndrome', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Prostaglandin', 'Receptors, Thromboxane', 'Receptors, Thrombox... | 8,481,403 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D02.455.426.100.080', 'D04.075.080'], ['D03.605.084'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D10.251.355'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['G01.374.661', 'G02.111.490'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does the bifunctional uridylate synthase channel orotidine 5'-phosphate? Kinetics of orotate phosphoribosyltransferase and orotidylate decarboxylase activities fit a noninteracting sites model. | Uridylate synthase is a bifunctional protein that first forms orotidine 5'-phosphate (OMP) from orotate via its orotate phosphoribosyltransferase activity (EC 2.4.2.10) and then converts OMP to uridine 5'-phosphate (UMP) via the OMP decarboxylase activity (EC 4.1.1.23). A computer modeling analysis of the experiments t... | ['Carboxy-Lyases', 'Kinetics', 'Models, Theoretical', 'Multienzyme Complexes', 'Orotate Phosphoribosyltransferase', "Orotidine-5'-Phosphate Decarboxylase", 'Pentosyltransferases', 'Time Factors', 'Uracil Nucleotides', 'Uridine Monophosphate'] | 3,651,388 | [['D08.811.520.224.125'], ['G01.374.661', 'G02.111.490'], ['E05.599'], ['D05.500.562', 'D08.811.600'], ['D08.811.913.400.725.700'], ['D08.811.520.224.125.450'], ['D08.811.913.400.725'], ['G01.910.857'], ['D03.383.742.686.850', 'D13.695.740.850', 'D13.695.827.919'], ['D03.383.742.686.850.877', 'D13.695.740.850.877', 'D1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Allograft interference screw fixation in meniscus transplantation. | Allograft meniscus transplantation is indicated to restore proper knee biomechanics and prevent subsequent articular degeneration in patients with a meniscus-deficient knee. A variety of techniques for fixation of meniscal transplants exist, with some techniques using soft-tissue fixation of the meniscal horns and othe... | ['Arthroscopy', 'Biomechanical Phenomena', 'Bone Screws', 'Humans', 'Knee Injuries', 'Menisci, Tibial', 'Tissue Transplantation', 'Transplantation, Homologous'] | 15,007,324 | [['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['G01.154.090', 'G01.374.089'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.165.308.538.500', 'A02.835.583.475.590', 'A10.165.382.350.163.500'], ['E02.095.14... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of possible occupational asthma in hairdressers working in hair salons for women. | BACKGROUND: The aim of this study was to determine the prevalence of possible occupational asthma (OA) in hairdressers.METHODS: A telephone questionnaire (Q1) was administered to 1,334 individuals from a total of 1,875 hairdressers working in hair salons for women in Barcelona (response rate 71%) to identify those with... | ['Adult', 'Asthma', 'Barbering', 'Dermatitis', 'Female', 'Hair Preparations', 'Humans', 'Male', 'Middle Aged', 'Occupational Diseases', 'Occupational Exposure', 'Prevalence', 'Rhinitis', 'Risk Factors', 'Spain', 'Surveys and Questionnaires'] | 21,346,368 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['J01.576.082'], ['C17.800.174'], ['D27.720.269.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C24'], ['N06.850.460.350.600'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.9... | ['Named Groups [M]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Etiology of specific types of dysphasia and dyslexia as well as their natural supporting mechanism (theoretical approach and therapeutic response)]. | The respective role of the organic and psychological factors is discussed. The importance of the individual's reaction to his own disorder is emphasized. This reaction according to the author promotes an evolution from a simple delay to a specific deviation. It is this reaction that the program "Natural Accompaniment" ... | ['Aphasia', 'Dyslexia', 'Humans', 'Language Therapy', 'Neuropsychology', 'Psychotherapy'] | 1,344,552 | [['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150.550.200', 'F03.625.562.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.727.344', 'E02.831.727.344'], ['F04.096.795... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of a radiation reduction campaign targeting children with gastrointestinal symptoms in a pediatric emergency department. | Children feature more active cellular division and a smaller body area, which leads to a greater radiation dosage accumulation. We tried to reduce radiation hazards by reducing unnecessary radiological studies in a pediatric emergency department (PED) through the radiation reduction campaign.Our campaign involved a red... | ['Child', 'Emergency Service, Hospital', 'Female', 'Gastrointestinal Diseases', 'Humans', 'Length of Stay', 'Male', 'Radiation Exposure', 'Radiography, Abdominal', 'Unnecessary Procedures'] | 28,099,351 | [['M01.060.406'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['C06.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['G01.750.748', 'N06.850.460.350.850'], ['E01.370.350.700.715'], ['N02.421.380.450.500', 'N05.300.150.395.450.500']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
On the pattern of organ growth in the common tern (Sterna hirundo). | Data are presented on the pattern of organ growth in the Common Tern, a semi-precocial bird species with a high growth rate, and are compared with data from some bird species within the altricial-precocial spectrum. The data show that a high growth rate is linked to a growth pattern characterized by a rapid early devel... | ['Animals', 'Birds', 'Body Weight', 'Digestive System', 'Feathers', 'Gizzard, Avian', 'Head', 'Heart', 'Intestines', 'Linear Models', 'Liver', 'Models, Biological', 'Muscle Development', 'Muscle, Skeletal', 'Neck', 'Pectoralis Muscles', 'Wings, Animal'] | 9,129,966 | [['B01.050'], ['B01.050.150.900.248'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A03'], ['A13.370'], ['A13.853.355'], ['A01.456'], ['A07.541'], ['A03.556.124'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Novel microarrays for simultaneous serodiagnosis of multiple antiviral antibodies. | We developed an automated diagnostic system for the detection of virus-specific immunoglobulin Gs (IgGs) that was based on a microarray platform. We compared efficacies of our automated system with conventional enzyme immunoassays (EIAs). Viruses were immobilized to microarrays using a radical cross-linking reaction th... | ['Antibodies, Viral', 'Azides', 'Herpesvirus 4, Human', 'Humans', 'Hydrocarbons, Fluorinated', 'Immunoenzyme Techniques', 'Immunoglobulin G', 'Mumps virus', 'Oligonucleotide Array Sequence Analysis', 'Rubella virus', 'Serologic Tests'] | 24,367,491 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D01.625.100', 'D02.159'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.510'], ['E05.478.566.350', 'E05.478.583.400', 'E05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dextromethorphan - A widely-used cough suppressant - Induces local anaphylaxis via MRGPRX2 on mast cells. | Dextromethorphan (DM) is a cough suppressant available in many prescribed and over-the-counter medications. Adverse reactions induced by DM have been regularly reported, including allergic skin reactions in some cases. However, the underlying mechanisms of local anaphylaxis induced by DM have not been elucidated. In th... | ['Anaphylaxis', 'Animals', 'Antitussive Agents', 'Cells, Cultured', 'Dextromethorphan', 'Gene Knockdown Techniques', 'HEK293 Cells', 'Humans', 'Mast Cells', 'Mice', 'Mice, Knockout', 'Nerve Tissue Proteins', 'Receptors, G-Protein-Coupled', 'Receptors, Neuropeptide'] | 32,871,113 | [['C20.543.480.099'], ['B01.050'], ['D27.505.954.427.153', 'D27.505.954.796.090'], ['A11.251'], ['D03.132.577.249.200', 'D03.605.497.212', 'D03.633.400.686.212', 'D04.615.723.795.200'], ['E05.393.335.500'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.427', 'A15.382... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age dependency of selenium and cadmium content in human liver, kidney, and thyroid. | Selenium and cadmium concentrations were investigated in 60 autopsy tissue samples obtained from fetal life up to adulthood (defined in this study as 25-87 y of age) in Styria, a moderately industrialized region in Austria that has a low selenium supply. During the first 2 y after birth, median liver selenium concentra... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Austria', 'Autopsy', 'Cadmium', 'Child', 'Child, Preschool', 'Female', 'Fetus', 'Gestational Age', 'Humans', 'Infant', 'Infant, Newborn', 'Kidney', 'Liver', 'Male', 'Middle Aged', 'Selenium', 'Spectrophotometry, Atomic', 'Thyro... | 7,618,958 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['Z01.542.088'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['M01... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Synthetic studies directed toward dideoxy lomaiviticinone lead to unexpected 1,2-oxazepine and isoxazole formation. | In the course of studies directed toward the synthesis of dideoxy lomaiviticinone, 3-(nitromethyl)cyclohexenones 2a (X = H) and 2b (X = I) were prepared. The corresponding enolates were reacted with naphthazarin (1) and unexpectedly afforded 1,2-oxazepine 3 and isoxazole 4, respectively. Rationale for their formation i... | ['Benzoquinones', 'Catalysis', 'Cyclohexanones', 'Isoxazoles', 'Molecular Structure', 'Oxazepines', 'Oxidation-Reduction', 'Polycyclic Compounds'] | 22,309,201 | [['D02.806.250'], ['G02.130'], ['D02.455.426.392.368.367.340', 'D02.522.400'], ['D03.383.129.385'], ['G02.111.570', 'G02.466'], ['D03.383.066.498'], ['G02.700', 'G03.295.531'], ['D04']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequency and size of micronuclei induced in gill cells of medaka fish (Oryzias latipes) after whole-body exposure to clastogenic chemicals. | Medaka fish (Oryzias latipes) were whole-bodily treated with various doses of mitomycin C (MMC), ethylmethanesulfonate (EMS), cyclophosphamide (CP), diethylnitrosamine (DEN), or colchicine (COL) for 24 h, and the frequency of micronucleated cells (MNCs) was measured in the gills at 24 and 48 h after treatment. In the p... | ['Animals', 'Cell Nucleus Size', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Gills', 'Micronuclei, Chromosome-Defective', 'Micronucleus Tests', 'Mutagens', 'Oryzias', 'X-Rays'] | 24,712,708 | [['B01.050'], ['G04.670.160'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['A13.421'], ['A11.284.430.106.570', 'A11.284.430.214.190.875.117.570', 'C23.550.210.570', 'G05.365.590.175.570'], ['E05.393.560.598'], ['D27.888.569.468'], ['B01.050.150.900.493.850.139.650'], ['G01.358.500.505.970', 'G01.750.250.970',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interrelationships among individual differences in alcohol demand, impulsivity, and alcohol misuse. | An Alcohol Purchase Task (APT) is a novel behavioral economic measure for characterizing the incentive value of alcohol to an individual (i.e., alcohol demand). Individual differences in alcohol demand have been associated with a number of alcohol-related outcomes and the current investigation sought to extend these pr... | ['Adult', 'Alcoholic Beverages', 'Alcoholism', 'Economics, Behavioral', 'Female', 'Humans', 'Impulsive Behavior', 'Individuality', 'Male', 'Motivation', 'Personality'] | 23,915,370 | [['M01.060.116'], ['G07.203.100.100', 'J02.200.100'], ['C25.775.100.250', 'F03.900.100.350'], ['F04.096.628.286', 'N03.219.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F01.752.488'], ['F01.658', 'F01.752.543.500.750'], ['F01.752']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Construction of a trifunctional cellulase and expression in Saccharomyces cerevisiae using a fusion protein. | BACKGROUND: Cellulose is the most important component of lignocellulose, and its degradation requires three different types of enzymes to act synergistically. There have been reports of single gene duality, but no gene has been described to have more than two functions. Cloning and expression of fusion cellulases conta... | ['Catalytic Domain', 'Cellulase', 'Cellulose', 'Lignin', 'Recombinant Fusion Proteins', 'Saccharomyces cerevisiae', 'beta-Glucosidase'] | 30,005,661 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.277.450.420.200.200'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['D12.776.828.300'], ['B01.300.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
William Penn and the peace of Europe. | The Quaker William Penn proposed a European Union to ensure peace in the continent in 1693. Penn was unusual among Quakers in being of the landed upper classes. When converted, he became a leader of the Quakers and other Dissenters. He had the two related ideals of peace and religious toleration, and dreamed of realizi... | ['Christianity', 'Cultural Evolution', 'Emigration and Immigration', 'Europe', 'History, 17th Century', 'Humans', 'Religion and Science', 'Religious Philosophies', 'United Kingdom', 'United States'] | 15,015,545 | [['K01.844.188'], ['I01.076.201.450.370'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.542'], ['K01.400.504.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.844.709'], ['K01.844.799'], ['Z01.542.363'], ['Z01.107.567.875']] | ['Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Expression and localization of fibroblast growth factor (FGF) family members during the final growth of bovine ovarian follicles. | The aim of this study was to investigate the possible participation of fibroblast growth factor (FGF) family members: FGF1, FGF2, and FGF7, and their receptor variants: FGFR, FGFR2IIIb, and FGFR2IIIc in theca interna (TI) and granulosa cell (GC) compartments of bovine follicles during final growth. A classification of ... | ['Animals', 'Base Sequence', 'Cattle', 'Female', 'Fibroblast Growth Factor 1', 'Fibroblast Growth Factor 2', 'Fibroblast Growth Factor 7', 'Fibroblast Growth Factors', 'Gene Expression Regulation, Developmental', 'Granulosa Cells', 'Immunohistochemistry', 'Ovarian Follicle', 'RNA, Messenger', 'Receptor, Fibroblast Grow... | 14,694,431 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['D12.644.276.624.110', 'D12.776.467.624.110', 'D23.529.624.110'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['D12.644.276.624.170', 'D12.776.467.624.170', 'D23.529.624.170'], ['D12... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Additional qualifications in "special pain therapy"--an advantage to surgeons as well?]. | Deficits in the treatment of patients with chronic pain lead the German Parliament of Physicians (Deutscher Arztetag) in 1996 to adapt a special curriculum called "Special Pain Treatment". Objectives and contents are defined in detail in guidelines accepted from 10 out of 17 federal commissions in Germany at this time.... | ['Chronic Disease', 'Curriculum', 'Education, Medical, Continuing', 'Education, Medical, Graduate', 'General Surgery', 'Germany', 'Humans', 'Legislation, Medical', 'National Health Programs', 'Pain', 'Specialization'] | 9,931,697 | [['C23.550.291.500'], ['I02.158'], ['I02.358.212.350', 'I02.358.399.250'], ['I02.358.337.350', 'I02.358.399.350'], ['H02.403.810.300'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.615.473'], ['N03.349.550'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['H02.811']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Regional distribution of gamma- and beta-endorphin-like peptides in the pituitary and brain of the rat. | Sensitive and specific radioimmunoassays for gamma- and beta-endorphin-like peptides (gamma E and beta E) were used to examine the distribution and relationship of these peptides in the pituitary and in microdissected nuclear brain areas of the male rat. In the pituitary, the highest amounts of gamma E and beta E were ... | ['Animals', 'Antibody Formation', 'Antibody Specificity', 'Brain Chemistry', 'Endorphins', 'Pituitary Gland', 'Radioimmunoassay', 'Rats', 'beta-Endorphin', 'gamma-Endorphin'] | 6,167,971 | [['B01.050'], ['G12.450.050.370.250'], ['G12.100'], ['G02.111.150', 'G03.185'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.357.352.435.500', 'A08.713.357.750'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit. | We have characterized in adult rat the tissue-specific expression of the nicotinic ACh receptor (AChR) beta 2-subunit using antisera raised against fusion protein constructs. Immunohistochemical localization revealed immunoreactivity distributed throughout the neuraxis. Overall, beta 2-like immunoreactivity (beta 2-LI)... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Brain', 'Immunohistochemistry', 'In Situ Hybridization', 'Molecular Probes', 'Molecular Sequence Data', 'Neurons', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Nicotinic', 'Recombinant Fusion Proteins', 'Tissue Distribution'] | 8,463,835 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Evolutionary dynamics of the 5S rDNA gene family in the mussel Mytilus: mixed effects of birth-and-death and concerted evolution. | In higher eukaryotes, the gene family encoding the 5S ribosomal RNA (5S rRNA) has been used (together with histones) to showcase the archetypal example of a gene family subject to concerted evolution. However, recent studies have revealed conspicuous features challenging the predictions of this model, including heterog... | ['Animals', 'Cluster Analysis', 'DNA', 'Evolution, Molecular', 'Mytilus', 'Nucleic Acid Conformation', 'Phylogeny', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'RNA, Ribosomal, 5S', 'RNA, Transfer, Arg'] | 20,386,892 | [['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308'], ['G05.045.250', 'G16.075.250'], ['B01.050.500.644.080.537.500'], ['G02.111.570.820.486', 'G05.360.580'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.365.795'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.3... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of the novel KIR2DL4*036 allele in a Chinese Hani individual. | The novel KIR2DL4*036 allele differs from the closest allele KIR2DL4*00102 by a single missense mutation. | ['Alleles', 'Asian Continental Ancestry Group', 'Base Sequence', 'Ethnic Groups', 'Exons', 'Humans', 'Mutation, Missense', 'Receptors, KIR2DL4'] | 31,069,992 | [['G05.360.340.024.340.030'], ['M01.686.508.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.686.754', 'N01.224.317'], ['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.650'], ['D12.776.543.750.705.895.500.468']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Advantages of periodic medical examinations of asbestos plant workers at the Occupational Center]. | The article deals with results of periodic medical examination conducted in Regional Occupational Center MONICI for 90 subjects working in apparatus workshop of asbestos ware plant. Data presented are results of thorough evaluation of respiration biomechanics through electronic spirometry and body plethysmography, seru... | ['Adult', 'Asbestosis', 'CA-125 Antigen', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mucin-1', 'Mucins', 'Occupations', 'Plethysmography, Whole Body', 'Risk Factors', 'Spirometry', 'Time Factors'] | 12,593,152 | [['M01.060.116'], ['C08.381.483.581.125', 'C08.381.520.702.125', 'C24.800.127'], ['D12.776.395.560.631.050', 'D23.050.285.050.225', 'D23.050.550.325.225', 'D23.101.140.075.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.395.550.560', 'D12.776.395.560.631.115', 'D12.776.543.550.530... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Modeling effects of sagittal-plane hip joint stiffness on reciprocating gait orthosis-assisted gait. | Upright ambulation is believed to improve quality of life for persons with lower-limb paralysis (LLP). However, ambulatory orthoses for persons with LLP, like reciprocating gait orthoses (RGOs), result in a slow, exhausting gait. Increasing the hip joint stiffness of these devices may improve the efficiency of RGO-assi... | ['Adult', 'Female', 'Gait', 'Hip Joint', 'Humans', 'Male', 'Models, Biological', 'Orthotic Devices', 'Range of Motion, Articular', 'Walking'] | 24,699,979 | [['M01.060.116'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E07.858.442.743'], ['E01.370.600.700', 'G11.427.760'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450.642.845.940']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Ultraviolet laser-induced fluorescence of colonic polyps. | Ultraviolet laser-induced fluorescence was examined in vivo to determine whether the technique can reliably distinguish between hyperplastic and adenomatous polyps of the colon. Spectra from 86 normal colonic sites, 35 hyperplastic polyps, and 49 adenomatous polyps were recorded in vivo. Polyp type was independently de... | ['Aged', 'Aged, 80 and over', 'Colonic Polyps', 'Diagnosis, Differential', 'Female', 'Fluorescence', 'Humans', 'Lasers', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Ultraviolet Rays'] | 1,551,525 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.825.411.235'], ['E01.171'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490', 'E07.710.520'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500']... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Semiautomatic segmentation and stenosis quantification of 3D contrast-enhanced MR angiograms of the internal carotid artery. | A technique is presented for the segmentation and quantification of stenosed internal carotid arteries (ICAs) in 3D contrast-enhanced MR angiography (CE-MRA). Segmentation with sub-pixel accuracy of the ICA is achieved via level-set techniques in which the central axis serves as the initialization. The central axis is ... | ['Algorithms', 'Anatomy, Cross-Sectional', 'Carotid Artery, Internal', 'Carotid Stenosis', 'Contrast Media', 'Gadolinium DTPA', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Angiography', 'Models, Biological', 'Observer Variation'] | 15,065,248 | [['G17.035', 'L01.224.050'], ['H01.158.100.185'], ['A07.015.114.186.200.230'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['D27.505.259.500', 'D27.720.259'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Undesirable Effects of Working While in College: Work-School Conflict, Substance Use, and Health. | Inter-role conflict occurs when the demands of one area of an individual's life interfere with the responsibilities of another area. Although a large body of research exists on the health effects of the inter-role conflict between work and family (work-family conflict or WFC), far less exists on the inter-role conflict... | ['Adolescent', 'Adult', 'Conflict, Psychological', 'Depression', 'Education', 'Employment', 'Female', 'Health', 'Humans', 'Male', 'Occupational Health', 'Stress, Psychological', 'Students', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'United States', 'Universities', 'Young Adult'] | 28,486,029 | [['M01.060.057'], ['M01.060.116'], ['F01.658.209'], ['F01.145.126.350'], ['I02'], ['N01.824.245'], ['N01.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.400.525'], ['F01.145.126.990', 'F02.830.900'], ['M01.848'], ['C25.775', 'F03.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Interleukin-1 beta polymorphisms are associated with lymph node metastasis in Korean patients with papillary thyroid carcinoma. | In this study, we investigated whether single nucleotide polymorphisms (SNPs) of the interleukin-1 beta (IL-1B) were associated with papillary thyroid carcinoma (PTC). We also assessed the relationships between IL-1B SNPs and the clinicopathologic characteristics of PTC patients. Ninety-three PTC patients and 324 contr... | ['Adult', 'Aged', 'Carcinoma', 'Carcinoma, Papillary', 'DNA Mutational Analysis', 'Female', 'Gene Frequency', 'Genetic Association Studies', 'Genotype', 'Humans', 'Interleukin-1beta', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Republic of Korea', 'Thyroid Cancer, Papillary', 'Thy... | 23,215,728 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['E05.393.760.700.300'], ['G05.330'], ['E05.393.385'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Differences in Treating Tobacco Use Across National, State, and Public Hospital System Surveys. | The Louisiana Tobacco Control Initiative (TCI), a multidisciplinary program specializing in helping tobacco users quit, assisted health care providers in Louisiana's public hospitals with integrating evidence-based treatment of tobacco use into clinical practice. Our study compared smoking behavior, provider adherence ... | ['Adolescent', 'Adult', 'Aged', 'Behavioral Risk Factor Surveillance System', 'Female', 'Humans', 'Louisiana', 'Male', 'Middle Aged', "Practice Patterns, Physicians'", 'Smoking', 'Smoking Cessation', 'Tobacco Use Disorder', 'United States', 'Young Adult'] | 30,124,428 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.980.438.149', 'N05.715.360.300.800.438.149', 'N06.850.520.308.980.438.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.750.480'], ['M01.060.116.630'], ['N04.590.374.577', 'N05.300.625'], ['F01.145.805'], ['F01.145.488.732'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clinical feasibility of computer-aided surgical simulation (CASS) in the treatment of complex cranio-maxillofacial deformities. | PURPOSE: The purpose of this study was to establish clinical feasibility of our 3-dimensional computer-aided surgical simulation (CASS) for complex craniomaxillofacial surgery.MATERIALS AND METHODS: Five consecutive patients with complex craniomaxillofacial deformities, including hemifacial microsomia, defects after tu... | ['Computer Simulation', 'Craniofacial Abnormalities', 'Craniotomy', 'Feasibility Studies', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Jaw Neoplasms', 'Male', 'Models, Anatomic', 'Patient Care Planning', 'Reconstructive Surgical Procedures', 'Surgery, Computer-Assisted', 'Temporomandibular Joint Disorders', 'Tom... | 17,368,370 | [['L01.224.160'], ['C05.660.207', 'C16.131.621.207'], ['E04.525.190'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['C04.588.149.721.450', 'C05.116.231.754.450', 'C05.500.499', 'C07.320.515'], ... | ['Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Peptide nucleic acids (PNAs): potential antisense and anti-gene agents. | The binding of peptide nucleic acids (PNAs) T10-LysNH2, T5CT4-LysNH2 and T2CT2CT4-LysNH2 to double-stranded DNA targets A10, A5GA4 and A2GA2GA4 was studied by nuclease S1 probing. It is found that the PNAs bind preferentially to their complementary targets, weaker to targets containing one mismatch and not to targets c... | ['Base Sequence', 'DNA', 'DNA-Directed DNA Polymerase', 'DNA-Directed RNA Polymerases', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Oligonucleotides, Antisense', 'Oligopeptides', 'Sensitivity and Specificity', 'Taq Polymerase', 'Transcription, Genetic'] | 8,476,502 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D08.811.913.696.445.308.300'], ['D08.811.913.696.445.735.270'], ['L01.453.245.667'], ['D13.695.578.424.450'], ['D13.150.480', 'D13.444.600.150.640', 'D13.695.578.424.480', 'D27.720.470.530.600.150.640'], ['D12.644.456'], ['E05.318.370.800', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Influence of postural anxiety on postural reactions to multi-directional surface rotations. | Previous studies have shown significant effects of increased postural anxiety in healthy young individuals when standing quietly or performing voluntary postural tasks. However, little is known about the influence of anxiety on reactive postural control. The present study examined how increased postural anxiety influen... | ['Adult', 'Anxiety', 'Electromyography', 'Female', 'Humans', 'Leg', 'Male', 'Muscle, Skeletal', 'Perception', 'Postural Balance', 'Posture', 'Rotation', 'Shoulder'] | 15,295,016 | [['M01.060.116'], ['F01.470.132'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['A02.633.567', 'A10.690.552.500'], ['F02.463.593'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G11.427.695'], ['G01.482.703'], ['A01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Are primary health care providers prepared to implement an anti-smoking program in Syria? | OBJECTIVE: To document primary health care (PHC) providers' tobacco use, and how this influences their smoking cessation practices and attitudes towards tobacco-control policies.METHODS: Anonymous questionnaires were distributed to PHC providers in 7 randomly selected PHC centers in Aleppo, Syria.RESULTS: All PHC provi... | ['Adult', 'Attitude of Health Personnel', 'Chi-Square Distribution', 'Female', 'Humans', 'Logistic Models', 'Male', 'Nurses', 'Physicians', 'Prevalence', 'Primary Health Care', 'Smoking', 'Smoking Cessation', 'Smoking Prevention', 'Surveys and Questionnaires', 'Syria'] | 21,168,300 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.71... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Escin induces apoptosis in human bladder cancer cells: An in vitro and in vivo study. | Escin (â-escin) is used as traditional folk medicine. The anti-tumour effects of escin have been demonstrated in vitro in certain cell lines, but its effect on bladder cancer has not been well investigated. In this study, the apoptotic activity of escin dissolved in dimethyl sulfoxide (DMSO) in bladder cancer cells and... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Caspases', 'Cell Cycle Checkpoints', 'Cell Proliferation', 'Escin', 'Female', 'Humans', 'Mice', 'Mitochondria', 'Reactive Oxygen Species', 'Receptors, Death Domain', 'Urinary Bladder Neoplasms', 'Xenograft Model Antitumor Assays'] | 30,287,153 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.144.109'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.455.849.919.530.333', 'D09.408.782.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conformational change of spermidine upon interaction with adenosine triphosphate in aqueous solution. | Endogenous polyamines, represented by putrescine, spermidine, and spermine, are known to exert their physiological functions by interacting with polyanionic biomolecules such as DNA, RNA, adenosine triphosphate (ATP), and phospholipids. Very few examples of conformation analysis have been reported for these highly flex... | ['Adenosine Triphosphate', 'Carbon Isotopes', 'Deuterium', 'Diamines', 'Hydrogen Bonding', 'Isomerism', 'Isotope Labeling', 'Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Polyphosphates', 'Putrescine', 'Spermidine', 'Water'] | 19,130,510 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D01.268.150.075', 'D01.496.123'], ['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['D02.092.782.258'], ['G02.282'], ['G02.111.570.685', 'G02.607.445'], ['E05.522'], ['E05.196.867.519'], ['G02.111.570.820'], ['D01.029.260.700.675.37... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease. | Caveolin-1 (Cav-1) is a regulatory protein of the arterial wall, but its role in human atherosclerosis remains unknown. We have studied the relationships between Cav-1 abundance, atherosclerotic plaque characteristics and clinical manisfestations of atherosclerotic disease.We determined Cav-1 expression by western blot... | ['Aged', 'Animals', 'Atherosclerosis', 'Carotid Artery Diseases', 'Caveolin 1', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Interleukin-6', 'Interleukin-8', 'Male', 'Matrix Metalloproteinase 9', 'Mice'] | 18,596,970 | [['M01.060.116.100'], ['B01.050'], ['C14.907.137.126.307'], ['C10.228.140.300.200', 'C14.907.253.123'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.05... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Pathology and epidemiology of canine distemper in raccoon dogs (Nyctereutes procyonoides). | From September to December 1991, a large number of free-ranging raccoon dogs (Nyctereutes procyonoides) died from a highly contagious disease in the vicinity of Tokyo. Eighteen seriously ill or dead animals were submitted for necropsy. The pathological findings resembled those in a masked palm civet (Paguma larvata) fo... | ['Acute Disease', 'Animals', 'Animals, Wild', 'Antigens, Viral', 'Carnivora', 'Central Nervous System', 'Disease Outbreaks', 'Distemper', 'Distemper Virus, Canine', 'Gastroenteritis', 'Inclusion Bodies, Viral', 'Japan', 'Lung', 'Lymphoid Tissue', 'Pneumonia, Viral'] | 8,366,205 | [['C23.550.291.125'], ['B01.050'], ['B01.050.050.300'], ['D23.050.327'], ['B01.050.150.900.649.313.750'], ['A08.186'], ['N06.850.290'], ['C01.925.782.580.600.500.285', 'C22.268.265'], ['B04.820.480.937.600.650.500.280'], ['C06.405.205'], ['A11.284.420.390', 'G06.920.400'], ['Z01.252.474.463', 'Z01.639.595'], ['A04.411'... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI. | BACKGROUND AND PURPOSE: This study uses T(2)* weighted imaging (T2*WI) to measure the temporal evolution of cerebral angiogenesis in rats subjected to embolic stroke up to 6 weeks after stroke onset with or without sildenafil treatment. Method- Male Wistar rats were subjected to embolic stroke and treated with saline (... | ['Animals', 'Brain', 'Brain Mapping', 'Cerebral Arteries', 'Diffusion Magnetic Resonance Imaging', 'Disease Models, Animal', 'Intracranial Embolism', 'Male', 'Microcirculation', 'Neovascularization, Physiologic', 'Piperazines', 'Predictive Value of Tests', 'Purines', 'Rats', 'Rats, Wistar', 'Recovery of Function', 'Sil... | 18,356,548 | [['B01.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A07.015.114.228'], ['E01.370.350.825.500.150'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.300.525.400', 'C14.907.253.566.300', 'C14.907.355.590.213.300'], ['G09.330.100.645'], ['G09.330.630'], ... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Late-Emerging and Resolving Dyslexia: A Follow-Up Study from Age 3 to 14. | This study focuses on the stability of dyslexia status from Grade 2 to Grade 8 in four groups: (a) no dyslexia in either grade (no-dyslexia, n = 127); (b) no dyslexia in Grade 2 but dyslexia in Grade 8 (late-emerging, n = 18); (c) dyslexia in Grade 2 but not in Grade 8 (resolving, n = 15); and (d) dyslexia in both grad... | ['Adolescent', 'Adult', 'Age of Onset', 'Child', 'Child Development', 'Child, Preschool', 'Disease Progression', 'Disease Susceptibility', 'Dyslexia', 'Female', 'Follow-Up Studies', 'Humans', 'Language Tests', 'Male', 'Parents', 'Prognosis', 'Risk'] | 25,772,426 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['C23.550.291.656'], ['C23.550.291.687', 'G07.100.250'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mp colorectal cancer should be defined as early colorectal cancer. | Little is known about the clinicopathologic features of mp colorectal cancer, defined as a cancer where the depth of invasion is limited to within the mucosa, the submucosa and the proper muscle. This study was designed to determine the clinicopathologic features of mp colorectal cancers. From 1973 to 1993, 83 mp color... | ['Colorectal Neoplasms', 'Female', 'Humans', 'Japan', 'Male', 'Multivariate Analysis', 'Neoplasm Invasiveness', 'Stomach Neoplasms', 'Survival Analysis', 'Time Factors'] | 9,699,244 | [['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C04.697.6... | ['Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Response to measles, mumps and rubella vaccine in paediatric bone marrow transplant recipients. | Bone marrow transplant (BMT) recipients are routinely reimmmunized with the childhood vaccine series after transplantation excluding the live attenuated vaccines. In this study, the clinical and serologic responses to measles, mumps and rubella (MMR) vaccine in children after BMT was assessed. Twenty-two BMT recipients... | ['Anemia, Aplastic', 'Antibodies, Viral', 'Bone Marrow Transplantation', 'Child', 'Child, Preschool', 'Contraindications', 'Genetic Diseases, Inborn', 'Graft vs Host Disease', 'Humans', 'Immunocompromised Host', 'Leukemia', 'Measles Vaccine', 'Measles virus', 'Measles-Mumps-Rubella Vaccine', 'Mumps Vaccine', 'Mumps vir... | 8,722,367 | [['C15.378.071.085', 'C15.378.190.223.250'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ['M01.060.406.448'], ['E02.208'], ['C16.320'], ['C20.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bioxanthracenes from the insect pathogenic fungus Cordyceps pseudomilitaris BCC 1620. II. Structure elucidation. | Structures of eleven bioxanthracenes (1 approximately 11) and two monomers (12 and 13), isolated from the insect pathogenic fungus Cordyceps pseudomilitaris BCC 1620, were elucidated. The structure, including the axial stereochemistry, of one of the major symmetrical dimers (1) was determined by X-ray crystallographic ... | ['Animals', 'Anthracenes', 'Crystallography, X-Ray', 'Dimerization', 'Hypocreales', 'Insecta', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Stereoisomerism'] | 11,269,713 | [['B01.050'], ['D02.455.426.559.847.117', 'D04.615.117'], ['E05.196.309.742.225'], ['G02.206', 'G03.230'], ['B01.300.107.501'], ['B01.050.500.131.617'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['G02.607.445.682']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomy changes in radiotherapy detected using portal imaging. | BACKGROUND AND PURPOSE: Localisation images normally acquired to verify patient positioning also contain information about the patient's internal anatomy. The aim of this study was to investigate the anatomical changes observed in localisation images and examples of dosimetric consequences.PATIENTS AND METHODS: Localis... | ['Diagnostic Imaging', 'Female', 'Head', 'Head and Neck Neoplasms', 'Humans', 'Lung', 'Lung Neoplasms', 'Male', 'Neck', 'Prostate', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted'] | 16,698,097 | [['E01.370.350'], ['A01.456'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['A01.598'], ['A05.360.444.575', 'A10.336.707'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.639'], ['E02.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vitreous relapse following primary chemotherapy for retinoblastoma: is adjuvant diode laser a risk factor? | AIMS: To evaluate rates of vitreous relapse among retinoblastoma patients treated with primary chemotherapy and assess diode laser as a potential risk factor for relapse.METHODS: Retrospective review of all patients treated with primary chemotherapy at a large ocular oncology centre. Eyes that developed vitreous relaps... | ['Antineoplastic Combined Chemotherapy Protocols', 'Child, Preschool', 'Combined Modality Therapy', 'Humans', 'Hyperthermia, Induced', 'Infant', 'Laser Therapy', 'Lasers', 'Neoplasm Seeding', 'Retinal Neoplasms', 'Retinoblastoma', 'Retrospective Studies', 'Risk Factors', 'Salvage Therapy', 'Survival Analysis', 'Vitreou... | 16,707,528 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['M01.060.406.448'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['M01.060.703'], ['E02.594', 'E04.014.520'], ['E07.632.490', 'E07.710.520'], ['C04.697.650.830', 'C23.550.727.650.830'], ['C04.588.364.818', 'C11.319.475', 'C11.768... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhancement of phagocytosis and bacterial killing by heterophils from neonatal chicks after administration of Salmonella enteritidis-immune lymphokines. | During the first week post-hatch, chickens demonstrate an increased susceptibility to infection by bacteria such as Salmonella. The purpose of the present study was to evaluate the effects of immune lymphokines on phagocytosis and killing activities of heterophils in chicks during the first 1-7 days of life. Lymphokine... | ['Animals', 'Chickens', 'Female', 'Granulocytes', 'Immunization', 'Lymphokines', 'Male', 'Phagocytosis', 'Poultry Diseases', 'Salmonella Infections, Animal', 'Salmonella enteritidis', 'Spleen', 'T-Lymphocytes'] | 10,078,597 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['D12.644.276.374.480... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Behavioral and mutagenic biomarkers in tadpoles exposed to different abamectin concentrations. | It is known that pesticides such as abamectin (ABA) present cytotoxic effects on target organisms; however, the effects from ABA on non-target organisms such as amphibians are poorly understood. The aim of the current study is to investigate whether the exposure of Lithobates catesbeianus tadpoles to different abamecti... | ['Animals', 'Behavior, Animal', 'Biomarkers', 'Ivermectin', 'Larva', 'Mutagenesis', 'Mutagens', 'Pesticides', 'Rana catesbeiana', 'Swimming'] | 29,478,167 | [['B01.050'], ['F01.145.113'], ['D23.101'], ['D02.540.576.500.997'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G05.558'], ['D27.888.569.468'], ['D27.720.031.700', 'D27.888.723'], ['B01.050.150.900.090.180.708.180'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845.945.500']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Implantation markers and endometriosis. | The receptive phase of the endometrium seems to occur in close association with the appearance of pinopodes and endometrial integrins that may be activated by the interleukin-1 system (IL-1). Embryo attachment is the result of adhesion protein expression, and the invasion of the embryo is governed by proteolytic enzyme... | ['Biomarkers', 'Embryo Implantation', 'Endometriosis', 'Endometrium', 'Estrogens', 'Female', 'Fertilization', 'Hormones', 'Humans', 'Infertility, Female', 'Interleukin-1', 'Interleukin-6', 'Killer Cells, Natural', 'Leukemia Inhibitory Factor', 'Lymphocytes', 'Models, Biological', 'Ovulation', 'Pregnancy', 'Urokinase-Ty... | 16,274,610 | [['D23.101'], ['G08.686.784.170.104.500'], ['C13.351.500.163'], ['A05.360.319.679.490'], ['D27.505.696.399.472.277'], ['G08.686.784.277'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obestatin does not modify weight and nutritional behaviour but is associated with metabolic syndrome in old women. | OBJECTIVE: Ghrelin and obestatin have apparent opposite orexigenic and anorexigenic effects, although the latter has not been firmly demonstrated in humans. So far, little data have been reported in relation to its potential association with metabolic syndrome (MS). The objective was to study obestatin concentrations i... | ['Aged', 'Aged, 80 and over', 'Anorexia Nervosa', 'Cohort Studies', 'Female', 'Ghrelin', 'Humans', 'Metabolic Syndrome', 'Nutritional Status', 'Obesity', 'Prospective Studies', 'Spain', 'Waist Circumference', 'Weight Loss'] | 22,775,400 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.400.125'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D06.472.699.301', 'D12.644.548.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['G07.203.650.650', 'N01.224.425.525'], ['C1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Biometric estimation of chest wall thickness of females. | Optimal use of whole-body counting data to estimate pulmonary deposition of many of the actinides is dependent upon accurate measurement of the thickness of the chest wall because of severe attenuation of low-energy x rays and photons associated with the decay of these radionuclides. An algorithm for estimation of fema... | ['Actinoid Series Elements', 'Adult', 'Anthropometry', 'Body Burden', 'Female', 'Humans', 'Lung', 'Thorax', 'Ultrasonography'] | 2,993,197 | [['D01.268.271.100', 'D01.496.749.305.100', 'D01.552.020'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E05.799.638.231', 'N06.850.460.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['A01.923.761'], ['E01.370.350.850']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation. | The action of some vascular smooth muscle relaxants depends on the presence of the endothelium. We have recently shown that relaxation may be mediated through the formation of cyclic GMP. The nitrovasodilators are another class of relaxants which exert their effects through the formation of cyclic GMP, although their r... | ['Acetylcholine', 'Animals', 'Aorta', 'Cyclic GMP', 'Endothelium', 'Isoelectric Point', 'Male', 'Molecular Weight', 'Muscle Contraction', 'Muscle Proteins', 'Muscle Relaxation', 'Muscle, Smooth, Vascular', 'Myosins', 'Nitroprusside', 'Phosphoproteins', 'Rats'] | 6,316,142 | [['D02.092.211.111'], ['B01.050'], ['A07.015.114.056'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['A10.272.491'], ['E05.301.300.663.500', 'G02.300.500'], ['G02.494'], ['G11.427.494'], ['D12.776.210.500'], ['G11.427.494.554'], ['A02.633.570.491', 'A07.015.733.500'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumor necrosis factor-alpha-induced lung injury and its modulation by synthetic polynucleotide: a physiologic-morphometric analysis. | PolyI:C, a potent interferon (IFN) inducer, protects the isolated perfused lung (IPL) against platelet-activating factor (PAF)-induced injury. Because the release of PAF is stimulated by tumor necrosis factor (TNF), this study was designed to measure the effects of polyI:C on TNF-induced lung inflammation and injury. T... | ['Animals', 'Arachidonic Acid', 'Hypertension, Pulmonary', 'In Vitro Techniques', 'Leukocytes, Mononuclear', 'Lung', 'Lung Injury', 'Male', 'Microscopy, Electron', 'Perfusion', 'Peroxidase', 'Poly I-C', 'Pulmonary Circulation', 'Pulmonary Edema', 'Rabbits', 'Recombinant Proteins', 'Tumor Necrosis Factor-alpha', 'Vascul... | 7,882,905 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['C08.381.423', 'C14.907.489.556'], ['E05.481'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['A04.411'], ['C08.381.520', 'C26.891.554'], ['E01.370.350.515.402', 'E05.595.402'], ['E05.680'], ['D08.811.682.732.700'], ['D13.695.578.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control of growth in cultured rat thyroid cells. | The purpose of this study was to determine the role of cAMP in the growth of FRTL and FRTL5 cells, 2 continuous cultured thyroid lines. TSH, at concentrations similar to those reported to induce growth in primary dog thyroid cultures, played an essential role for growth. Stimulators of adenylate cyclase, cholera toxin ... | ['1-Methyl-3-isobutylxanthine', 'Animals', 'Bucladesine', 'Cell Division', 'Cell Line', 'Cholera Toxin', 'Colforsin', 'Cyclic AMP', 'Rats', 'Rats, Inbred F344', 'Thyroid Gland', 'Thyrotropin'] | 2,420,657 | [['D03.633.100.759.758.824.751.500'], ['B01.050'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PEG Insertion in Patients With Dementia Does Not Improve Nutritional Status and Has Worse Outcomes as Compared With PEG Insertion for Other Indications. | BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) tubes are commonly utilized as a method of enteral feeding in patients unable to obtain adequate oral nutrition. Although some studies have shown improved mortality in select populations, the safety and effectiveness of PEG insertion in patients with dementia compar... | ['Aged', 'Aged, 80 and over', 'Biomarkers', 'Clinical Decision-Making', 'Databases, Factual', 'Dementia', 'Enteral Nutrition', 'Female', 'Gastroscopy', 'Gastrostomy', 'Geriatric Assessment', 'Humans', 'Male', 'Malnutrition', 'Middle Aged', 'Nutrition Assessment', 'Nutritional Status', 'Patient Readmission', 'Patient Se... | 27,505,401 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['E01.055'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C10.228.140.380', 'F03.615.400'], ['E02.421.360', 'E02.642.500.360'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['E04.210.496... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
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