Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Visual search for transparency and opacity: attentional guidance by cue combination? | A series of seven experiments explored search for opaque targets among transparent distractors or vice versa. Static stimuli produced very inefficient search. With moving items, search for an opaque target among transparent distractors was quite efficient while search for transparent targets was less efficient (Experim... | ['Attention', 'Cues', 'Humans', 'Visual Perception'] | 15,929,650 | [['F02.830.104.214'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932']] | ['Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
It's important, but not important enough: eHealth as a curriculum priority in medical education in Australia. | Information and communications technology has become central to the way in which health services are provided. Technology-enabled services in healthcare are often described as eHealth, or more recently, digital health. Practitioners may require new knowledge, skills and competencies to make best use of eHealth, and whi... | ['Adult', 'Australia', 'Curriculum', 'Education, Medical', 'Female', 'Health Personnel', 'Humans', 'Male', 'Medical Informatics', 'Telemedicine'] | 30,343,657 | [['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['I02.158'], ['I02.358.399'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800']] | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
The relationship between therapy intensity and rehabilitative outcomes after traumatic brain injury: a multicenter analysis. | OBJECTIVES: To identify factors relating to the intensity of rehabilitation services received and to ascertain the relation between injury outcomes, demographics, types of therapy, and the intensity of rehabilitation services provided.DESIGN: A multicenter, prospective, nonrandomized study with inpatient rehabilitation... | ['Adult', 'Brain Injuries', 'Cognition', 'Female', 'Health Status', 'Health Status Indicators', 'Humans', 'Male', 'Motor Skills', 'Physical Therapy Modalities', 'Prospective Studies', 'Regression Analysis', 'Rehabilitation Centers', 'Time Factors', 'Treatment Outcome'] | 14,586,910 | [['M01.060.116'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F02.463.188'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808.260'], ['E02.779', 'E... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Isolation and characterization of LNCaP sublines differing in hormone sensitivity. | Prostate cancer is a heterogeneous disease with varying degrees of androgen sensitivity. In this study, we performed a limiting dilution of human prostate LNCaP cells, and isolated two sublines, LNCaP-E9 and LNCaP-G4, with differential hormone-sensitivity. Two LNCaP sublines were obtained by the limiting dilution metho... | ['Androgens', 'Animals', 'Carcinoma', 'Carrier Proteins', 'Cell Culture Techniques', 'Cell Line, Tumor', 'Cell Proliferation', 'Clone Cells', 'Humans', 'Male', 'Mice', 'Mice, SCID', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Zinc'] | 17,409,465 | [['D27.505.696.399.472.161'], ['B01.050'], ['C04.557.470.200'], ['D12.776.157'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased melatonin may play dual roles in the striata of a 6-hydroxydopamine model of Parkinson's disease. | AIMS: To investigate dynamic changes and roles of melatonin (MLT) in the striata of 6-hydroxydopamine (6-OHDA)-treated rats.MAIN METHODS: A Parkinson's disease (PD) rat was established by a unilateral injection of 6-OHDA into the right substantia nigra pars compacta (SNc) and the right medial forebrain bundle (MFB) to ... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Chromatography, High Pressure Liquid', 'Corpus Striatum', 'Data Interpretation, Statistical', 'Disease Models, Animal', 'Dopamine', 'Homovanillic Acid', 'Male', 'Melatonin', 'Microdialysis', 'Oxidopamine', 'Parkinson Disease, Secondary', 'Rats', 'Rats, Sprague-Dawley'] | 23,333,823 | [['D02.241.223.601.220'], ['B01.050'], ['E05.196.181.400.300'], ['A08.186.211.200.885.287.249.487'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Inhibition of Tnf-á R1 signaling can rescue functional cortical plasticity impaired in early post-stroke period. | Tumor necrosis factor-á (TNF-á) is one of the key players in stroke progression and can interfere with brain functioning. We previously documented an impairment of experience-dependent plasticity in the cortex neighboring the stroke-induced lesion, which was accompanied with an upregulation of Tnf-á level in the brain ... | ['Animals', 'Binding, Competitive', 'Brain', 'Female', 'Infusion Pumps', 'Mice, Inbred C57BL', 'Molecular Targeted Therapy', 'Neuronal Plasticity', 'Receptors, Tumor Necrosis Factor, Type I', 'Signal Transduction', 'Somatosensory Cortex', 'Stroke', 'Time Factors', 'Tumor Necrosis Factor-alpha'] | 26,189,092 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A08.186.211'], ['E07.505', 'E07.858.082.505'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E02.319.574'], ['G11.561.638'], ['D12.776.543.750.690.750', 'D12.776.543.750.705.852.760.597'], ['G02.111.820', 'G04... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Substrate recognition by a sucrose transporting protein. | Protoplasts derived from developing soybean cotyledons were used to study substrate recognition by a sucrose transporting protein in plant membranes. When used as alternate substrate inhibitors of [14C] sucrose influx, five different fructosyl-substituted sucrose derivatives, phenyl-alpha-D-glucopyranoside, and phenyl-... | ['Carrier Proteins', 'Models, Molecular', 'Plant Proteins', 'Soybeans', 'Substrate Specificity', 'Sucrose', 'Thioglycosides'] | 3,745,177 | [['D12.776.157'], ['E05.599.595'], ['D12.776.765'], ['B01.650.940.800.575.912.250.401.750'], ['G02.111.835'], ['D09.698.629.305.770', 'D09.947.750.770'], ['D02.886.740', 'D09.408.903']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fasting induces modifications of the endoplasmic reticulum in intestinal cells. | The polymorphism of the endoplasmic reticulum (ER) in epithelial cells with different transport functions such as the enterocyte suggests that the ER may be involved in some way in molecular transport. To further access this possibility, we examined the ER from the intestine of winter flounder, Pseudopleuronectes ameri... | ['Animals', 'Biological Transport', 'Cecum', 'Endoplasmic Reticulum', 'Epithelium', 'Fasting', 'Flounder', 'Intestinal Mucosa', 'Intestines', 'Jejunum', 'Leucyl Aminopeptidase', 'Osmium', 'Phenylalanine', 'Rats', 'Seasons'] | 2,213,232 | [['B01.050'], ['G03.143'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['A11.284.430.214.190.875.248'], ['A10.272'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['B01.050.150.900.493.418.438'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['A03.556.124.684.500', 'A03.556.249.750']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of the AdhSL regulatory mutation in Drosophila melanogaster. | We describe the characterization of a previously reported control mutation, AdhSL, in the alcohol dehydrogenase gene of Drosophila melanogaster, which results in decreased production of ADH molecules and subsequently lower ADH activity in adults. We find that the regulatory element modifies ADH mRNA levels and acts cis... | ['Aldehyde Dehydrogenase', 'Animals', 'DNA Restriction Enzymes', 'Drosophila melanogaster', 'Gene Expression Regulation', 'Genes', 'Genes, Regulator', 'Mutation', 'Nucleotide Mapping', 'RNA, Messenger', 'Transcription, Genetic'] | 2,841,189 | [['D08.811.682.657.163.249'], ['B01.050'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.308'], ['G05.360.340.024.340'], ['G05.360.340.024.340.425'], ['G05.365.590'], ['E05.196.181.400.454.655', 'E05.196.401.319.670', 'E05.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interleukin 10 treatment of patients with rheumatoid arthritis enhances Fc gamma receptor expression on monocytes and responsiveness to immune complex stimulation. | OBJECTIVE: Several clinical studies performed with human recombinant interleukin 10 (IL-10) in patients with rheumatoid arthritis (RA) have shown little efficacy. We investigated potentially proinflammatory in vivo effects of IL-10 in humans. We evaluated the upregulation of Fc gamma receptor (Fc gamma R) expression on... | ['Antigen-Antibody Complex', 'Arthritis, Rheumatoid', 'C-Reactive Protein', 'Humans', 'In Vitro Techniques', 'Interleukin-10', 'Macrophages', 'Monocytes', 'Receptors, IgG', 'Up-Regulation'] | 12,672,180 | [['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment for infertility: counting the cost. | This paper looks at the provision of infertility treatment in the UK. In August this year the College of Health reported on the funding and provision of fertility services and found that local variations in access to services still exist. | ['Female', 'Financing, Government', 'Health Care Costs', 'Health Services Accessibility', 'Humans', 'Infertility', 'Male', 'United Kingdom'] | 7,991,373 | [['N03.219.521.346'], ['N03.219.151.400', 'N05.300.375'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365', 'C13.351.500.365'], ['Z01.542.363']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Cytoplasm segmentation on cervical cell images using graph cut-based approach. | This paper proposes a method to segment the cytoplasm in cervical cell images using graph cut-based algorithm. First, the A* channel in CIE LAB color space is extracted for contrast enhancement. Then, in order to effectively extract cytoplasm boundaries when image histograms present non-bimodal distribution, Otsu multi... | ['Algorithms', 'Automation', 'Cell Nucleus', 'Cervix Uteri', 'Contrast Media', 'Cytoplasm', 'Female', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Programming Languages', 'Software', 'Uterine Cervical Neoplasms'] | 24,212,005 | [['G17.035', 'L01.224.050'], ['J01.897.104'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A05.360.319.679.256'], ['D27.505.259.500', 'D27.720.259'], ['A11.284.430.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['L01.224.308'], ['L01.224.900.780'], ['L01.224... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Isolation and characterization of a high-molecular-weight polysaccharide from the slime of Pseudomonas aeruginosa. | A procedure is described for isolating a high-molecular-weight polysaccharide (PS) from the slime of Pseudomonas aeruginosa immunotype 1. The resultant material, obtained from the void volume of a Sephadex G-100 column, was composed of carbohydrate and water. No lipopolysaccharide (LPS), 2-keto-3-deoxyoctonoate, heptos... | ['Antigens, Bacterial', 'Lipopolysaccharides', 'Molecular Weight', 'Polysaccharides, Bacterial', 'Pseudomonas aeruginosa'] | 103,840 | [['D23.050.161'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['G02.494'], ['D09.698.718', 'D23.050.161.616'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of a glycogen-loading regimen on the capacity to perform anaerobic exercise. | The effect of a pattern of exercise and dietary modifications, which was designed to produce alterations in the muscle glycogen content, on the capacity to perform anaerobic exercise was investigated. Six young male subjects worked to exhaustion on a bicycle ergometer at a supramaximal work load equivalent to 104 +/- 5... | ['Adult', 'Blood Glucose', 'Diet', 'Glycogen', 'Humans', 'Lactates', 'Male', 'Muscles', 'Physical Exertion', 'Respiration'] | 7,195,804 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['G07.203.650.240'], ['D05.750.078.562.388', 'D09.698.365.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459'], ['A02.633', 'A10.690'], ['G11.427.683'], ['G09.772.705']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism. | Mevalonate kinase (MK), which catalyzes a key reaction in polyisoprenoid and sterol metabolism in many organisms, is subject to feedback regulation by farnesyl diphosphate and related compounds. The structures of human mevalonate kinase and a binary complex of the rat enzyme incubated with farnesyl thiodiphosphate (FSP... | ['Adenosine Triphosphate', 'Amino Acid Sequence', 'Animals', 'Binding Sites', 'Crystallography, X-Ray', 'Feedback, Physiological', 'Humans', 'Models, Molecular', 'Phosphotransferases (Alcohol Group Acceptor)', 'Polyisoprenyl Phosphates', 'Rats', 'Sequence Alignment', 'Streptococcus pneumoniae'] | 18,302,342 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['G07.410.732'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['D08.811.913.696.620'], ['D02.455.849.690', 'D02.705.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Visualization and unsupervised predictive clustering of high-dimensional multimodal neuroimaging data. | BACKGROUND: Neuroimaging machine learning studies have largely utilized supervised algorithms - meaning they require both neuroimaging scan data and corresponding target variables (e.g. healthy vs. diseased) to be successfully 'trained' for a prediction task. Noticeably, this approach may not be optimal or possible whe... | ['Adolescent', 'Adult', 'Algorithms', 'Artificial Intelligence', 'Brain', 'Cluster Analysis', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Neuroimaging', 'Principal Component Analysis', 'Sex Characteristics', 'Stochastic Processes... | 25,117,552 | [['M01.060.057'], ['M01.060.116'], ['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['A08.186.211'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.567'], ['E0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A simple, cheap, one-minute method to mount insect pins for use as sharp-tipped probes in plant dissection. | A new method is presented for twist mounting insect pins onto standard dissecting (teasing) needles. Insect pins, with their sharp points, are ideal for fine dissection of plants, especially of shoot tips and early developing flower buds. Twist mounting makes them convenient and effective dissecting tools to prepare sp... | ['Animals', 'Dissection', 'Flowers', 'Heliotropium', 'Insecta', 'Microscopy, Electron, Scanning', 'Needles', 'Plants'] | 16,143,702 | [['B01.050'], ['E01.370.225.998.221', 'E04.221', 'E05.200.998.221'], ['A18.024.249.500'], ['B01.650.940.800.575.912.250.150.444'], ['B01.050.500.131.617'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E07.612'], ['B01.650']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative characterization of the binding of plasminogen to intact fibrin clots, lysine-sepharose, and fibrin cleaved by plasmin. | The binding of human Glu- and Lys-plasminogens to intact fibrin clots, to lysine-Sepharose, and to fibrin cleaved by plasmin was quantitatively characterized. On intact fibrin clots, there was one strong binding site for Glu-plasminogen with a dissociation constant, Kd, of 25 microM and one strong binding site for Lys-... | ['Affinity Labels', 'Blood Coagulation', 'Fibrin', 'Fibrinolysin', 'Humans', 'Iodine Radioisotopes', 'Kinetics', 'Peptide Fragments', 'Plasminogen', 'Protein Binding', 'Sepharose'] | 3,161,540 | [['D27.720.470.410.080'], ['G09.188.390.150'], ['D12.776.124.270'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['G01.374.661', 'G02.111.490'], ['D12.644.541'], ['D08.622.610', 'D12.77... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Some serological cross-reactions between Streptococcus mutans, S sanguis, and other dental plaque streptococci. | From the preliminary observations described in this report, the following conclusions may be drawn. When attempting to produce diagnostic antiserums specific for S mutans, S mitior, or S sanguis, care must be taken to eliminate cross-reactions as a result of antibodies against extracellular glucans or dextrans. Other a... | ['Agglutination', 'Antigens, Bacterial', 'Cell Wall', 'Chemical Fractionation', 'Chemical Precipitation', 'Chromatography, Gel', 'Chromatography, Ion Exchange', 'Cross Reactions', 'Dental Plaque', 'Glucose', 'Humans', 'Immune Sera', 'Polysaccharides, Bacterial', 'Streptococcus', 'Streptococcus mutans', 'Streptococcus s... | 1,063,153 | [['G02.111.026', 'G12.122.100'], ['D23.050.161'], ['A11.284.183'], ['E05.196.155'], ['E05.196.150', 'G02.159'], ['E05.196.181.400.250'], ['E05.196.181.400.383'], ['G12.122.281'], ['C07.793.208.377'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.1... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stable homogeneous gel for molecular-sieving of DNA fragments in capillary electrophoresis. | A polyacrylamide gel crosslinked with allyl-beta-cyclodextrin can be used repeatedly for several weeks for the separation of DNA fragments, since bubbles are not generated during a run. Allyl-beta-cyclodextrin can easily be synthesized in one step from allylglycidylether and beta-cyclodextrin. The plate numbers for DNA... | ['Base Pairing', 'DNA', 'Electrophoresis, Capillary'] | 12,150,560 | [['G02.111.570.820.486.100', 'G02.111.611.500', 'G05.360.580.100'], ['D13.444.308'], ['E05.196.401.190', 'E05.301.300.190']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Restricted appearance of tenascin and chondroitin sulphate proteoglycans after transection and sprouting of adult rat postcommissural fornix. | Transected fibres of the adult rat postcommissural fornix sprout over short distances but fail to traverse the lesion site and terminate in close vicinity to the wound. As a step in defining the molecular environment responsible for regeneration failure at the lesion site, we have used immunocytochemistry to analyse th... | ['Animals', 'Axons', 'Brain', 'Brain Injuries', 'Chondroitin Sulfates', 'Female', 'Immunohistochemistry', 'Male', 'Nerve Fibers', 'Nerve Regeneration', 'Proteoglycans', 'Rats', 'Rats, Wistar', 'Tenascin'] | 7,595,661 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.186.211'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['D09.698.373.200.300'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.65... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Maximizing Ion-Tagged Oligonucleotide Loading on Magnetic Ionic Liquid Supports for the Sequence-Specific Extraction of Nucleic Acids. | Targeted nucleic acid analysis requires the highly selective extraction of desired DNA fragments in order to minimize interferences from samples with abundant heterogeneous sequences. We previously reported a method based on functionalized oligonucleotide probes known as ion-tagged oligonucleotides (ITOs) that hybridiz... | ['DNA, Bacterial', 'Escherichia coli', 'Humans', 'Immunomagnetic Separation', 'Ionic Liquids', 'Nucleic Acids', 'Oligonucleotide Probes', 'Proto-Oncogene Proteins p21(ras)', 'Real-Time Polymerase Chain Reaction'] | 30,995,833 | [['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.437', 'E05.200.500.363.441', 'E05.242.363.441'], ['D27.720.844.500'], ['D13.444'], ['D13.444.600.601', 'D27.505.259.750.600.650', 'D27.720.470.530.600.650'], ['D08.811.277.040.330.300... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
De novo metagenomic assembly reveals abundant novel major lineage of Archaea in hypersaline microbial communities. | This study describes reconstruction of two highly unusual archaeal genomes by de novo metagenomic assembly of multiple, deeply sequenced libraries from surface waters of Lake Tyrrell (LT), a hypersaline lake in NW Victoria, Australia. Lineage-specific probes were designed using the assembled genomes to visualize these ... | ['Australia', 'Euryarchaeota', 'Genome, Archaeal', 'Lakes', 'Metagenomics', 'Molecular Sequence Data', 'Phylogeny', 'Salinity', 'Victoria'] | 21,716,304 | [['Z01.639.100', 'Z01.678.100.373'], ['B02.200'], ['G05.360.340.358.050'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['H01.158.273.343.350.261'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.640.500'], ['Z01.639.100.992', 'Z01.678.100.373.992']] | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Semi-mechanistic model for neutropenia after high dose of chemotherapy in breast cancer patients. | PURPOSE: To describe the absolute neutrophil counts (ANC) profile in breast cancer patients receiving high-dose of chemotherapy and peripheral blood stem-cells (PBSC) transplantation.METHODS: Data from 41 subjects receiving cyclophosphamide, thiotepa and carboplatin were used to develop the ANC model consisting of a dr... | ['Antineoplastic Agents', 'Breast Neoplasms', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Middle Aged', 'Models, Biological', 'Neutropenia'] | 19,488,837 | [['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.395'], ['C15.378.553.546.184.564']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A malignant carcinoid tumour of the supraglottic larynx. | A rare case of carcinoid tumour of the laryngeal surface of the epiglottis in a 49-year-old woman is presented. This is the fourth report of this tumour in the world literature. The clinical features, and the light and electron microscopical appearances are discussed. The literature and the relationship to other carcin... | ['Carcinoid Tumor', 'Epiglottis', 'Female', 'Humans', 'Laryngeal Neoplasms', 'Microscopy, Electron', 'Middle Aged'] | 7,288,280 | [['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['A02.165.257.625.411', 'A02.165.407.500.411', 'A04.329.591.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E01.370.350.515.402', 'E05.595.40... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Experience with the dynamic compression plate (DCP) in 418 recent fractures of the tibial shaft. | A consecutive series of 435 fresh fractures of the tibial shaft was internally fixed by the new dynamic compression plate (ASIF-DCP). All but 2 cases could be reviewed personally within 1-2 years after operation, while 15 patients had died. The functional results and postoperative complications are reported separately ... | ['Adolescent', 'Adult', 'Aged', 'Bone Plates', 'Evaluation Studies as Topic', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Fractures, Closed', 'Fractures, Open', 'Humans', 'Male', 'Middle Aged', 'Osteitis', 'Postoperative Complications', 'Tibia', 'Tibial Fractures', 'Wound Healing', 'Wound Infection'] | 1,278,983 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E05.337', 'N05.715.360.335'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['C26.404.124'], ['C26.404.311'], ['B01.050.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[New principles and technology in the management of medical research]. | New principles of management, planning, and finance of medical science with the aim to increase its efficacy are discussed. The transfer from financing the scientific administration to financing research is taken into account. The technology of expert examination is analysed as this is a basis for adopting decisions in... | ['Health Planning', 'Health Planning Technical Assistance', 'Health Services Research', 'Humans', 'USSR'] | 2,368,483 | [['N03.349', 'N03.706.615.302'], ['N03.349.325'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.931', 'Z01.586.950']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Regulation of fat synthesis by conjugated linoleic acid: lactation and the ruminant model. | Conjugated linoleic acid (CLA) isomers effect an impressive range of biological processes including the ability to inhibit milk fatty acid synthesis. Although this has been demonstrated in several mammals, research has been most extensive with dairy cows. The first isomer shown to affect milk fat synthesis during lacta... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Cattle', 'Diet', 'Fats', 'Female', 'Lactation', 'Linoleic Acids, Conjugated', 'Milk', 'Models, Animal'] | 18,203,911 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['D10.212'], ['G08.686.523', 'G08.686.702.500'], ['D10.251.355.343.500.750'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The risk of infection-related hospitalization with decreased kidney function. | BACKGROUND: Moderate kidney disease may predispose to infection. We sought to determine whether decreased kidney function, estimated by serum cystatin C level, was associated with the risk of infection-related hospitalization in older individuals.STUDY DESIGN: Cohort study.SETTING & PARTICIPANTS: 5,142 Cardiovascular H... | ['Aged', 'Cohort Studies', 'Female', 'Glomerular Filtration Rate', 'Hospitalization', 'Humans', 'Infections', 'Kidney', 'Male', 'Risk Factors'] | 21,906,862 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.390.400.300', 'G08.852.357'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['A05.810.453'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immune response and protective effect against spring viremia of carp virus induced by intramuscular vaccination with a SWCNTs-DNA vaccine encoding matrix protein. | To elicit the immune protective of vaccine against the highly contagious and pathogenic disease caused by spring viremia of carp virus (SVCV), a novel functionalized single-walled carbon nanotubes (SWCNTs) were applied as a delivery vehicle for DNA vaccine. In this study, we report a SWCNTs-DNA vaccine encoding matrix ... | ['Animals', 'Fish Diseases', 'Injections, Intramuscular', 'Nanotubes, Carbon', 'Rhabdoviridae', 'Rhabdoviridae Infections', 'Vaccination', 'Vaccines, DNA', 'Viral Matrix Proteins', 'Viral Vaccines'] | 29,777,766 | [['B01.050'], ['C22.362'], ['E02.319.267.530.460'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['B04.820.480.937.750'], ['C01.925.782.580.830'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.421.726.758.310.890', 'N06.850.780.200.425.900', 'N06.850.780.680.310.890'], ['D12.776.828.868.910', 'D20.215.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The impact and outcome of transplant coronary artery disease in a pediatric population: a 9-year multi-institutional study. | BACKGROUND: Transplant coronary artery disease (TCAD) limits survival in heart transplant recipients; however, its incidence in children is unknown. The purpose of this study was to determine the angiographic incidence of TCAD, potential risk factors, and outcomes in a large pediatric cohort.METHODS: From January 1993 ... | ['Adolescent', 'Child', 'Child, Preschool', 'Coronary Angiography', 'Coronary Artery Disease', 'Follow-Up Studies', 'Graft Survival', 'Heart Transplantation', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Survival Rate', 'Treatment Outcome'] | 15,949,722 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[
Investing in human resources for health in French-speaking Africa: the contribution of the Muskoka project.] | This introduction presents the articles included in this special issue on “investing in human resources for health in French-speaking Africa”. It starts by placing the human resources issue in the context of the pursuit of the Sustainable Development Goals adopted by the United Nations General Assembly in 2015. It then... | ['Africa', 'France', 'Health Workforce', 'Humans', 'International Cooperation', 'Language', 'United Nations', 'World Health Organization'] | 30,066,554 | [['Z01.058'], ['Z01.542.286'], ['N02.350', 'N04.452.525.500', 'N05.300.420.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['F01.145.209.399', 'L01.559'], ['N03.540.514.718'], ['N03.540.514.718.800']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Polymerase chain reaction (PCR) for the detection of Salmonella in artificially inoculated chicken meat. | The aim of this study was to develop a polymerase chain reaction (PCR) protocol for the detection of Salmonella in artificially contaminated chicken meat. Tests were performed with different dilutions of Salmonella Typhimurium or Salmonella Enteritidis cells (10(-7), 10(-8) or 10(-9) CFU/mL) inoculated in chicken meat ... | ['Animals', 'Chickens', 'DNA, Bacterial', 'Polymerase Chain Reaction', 'Poultry Products', 'Salmonella', 'Time Factors'] | 11,696,845 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.444.308.212'], ['E05.393.620.500'], ['G07.203.300.600.750.500', 'J02.500.600.750.500'], ['B03.440.450.425.800', 'B03.660.250.150.710'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The influence of training length on generalization of visual feature assemblies in honeybees. | Generalization is a fundamental cognitive ability that allows treating similar stimuli as equivalents, and thus responding to them in the same manner. Here, we show that after training free-flying bees with a single, constant pair of patterns made of four quadrants, each displaying different oriented gratings, bees ext... | ['Analysis of Variance', 'Animals', 'Bees', 'Behavior, Animal', 'Conditioning, Classical', 'Discrimination Learning', 'Generalization, Psychological', 'Generalization, Stimulus', 'Homing Behavior', 'Maze Learning', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Spatial Behavior', 'Time Factors'] | 15,904,705 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['F01.145.113'], ['F02.463.425.179.308'], ['F02.463.425.280'], ['F02.463.425.357'], ['F02.463.425.357.526'], ['F01.145.113.646'], ['F02.463.425.874.500'], ['F02.463.593.524.500', 'F02.463.593.93... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of dietary calcium and cadmium on cadmium accumulation, calcium and cadmium uptake from the water, and their interactions in juvenile rainbow trout. | The objective of this study was to examine the effects of chronically elevated dietary Ca2+ (as CaCO3), alone and in combination with elevated dietary Cd, on survival, growth, and Cd and Ca2+ accumulation in several internal compartments in juvenile rainbow trout (Oncorhynchus mykiss). In addition, effects on short-ter... | ['Animals', 'Biological Transport', 'Cadmium', 'Cadmium Radioisotopes', 'Calcium Radioisotopes', 'Calcium, Dietary', 'Fresh Water', 'Gills', 'Ion Transport', 'Oncorhynchus mykiss', 'Scintillation Counting', 'Time Factors', 'Tissue Distribution'] | 15,748,750 | [['B01.050'], ['G03.143'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.496.749.108'], ['D01.268.552.100.500.325', 'D01.496.098.325', 'D01.496.749.113', 'D01.552.539.288.500.325'], ['D01.146.395'], ['G16.500.275.280', 'N06.230.232'], ['A13.421'], ['G03.143.500'], ['B01.050.150.900.493.817.750.825.58... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The psychological implications of spontaneous abortions. | Spontaneous abortion occurs in approximately 15% of obstetric patients. Our efforts to decrease bleeding and prevent infection do not take into account the emotional stress of the patient or the sense of grief and loss she might be feeling. Predominantly, the women in this study were concerned with what caused the misc... | ['Abortion, Spontaneous', 'Adult', 'Emotions', 'Family Planning Services', 'Female', 'Humans', 'Pregnancy'] | 7,431,363 | [['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.116'], ['F01.470'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A panel of specific monoclonal antibodies directed against various phosphorylated histones H3. | Modification of histone plays a critical role in the epigenetic regulation of gene expression. However, unlike the widely studied roles of histone methylation or acetylation of histone H3, relatively little is known about the molecular mechanisms involved in translating histone phosphorylation into a specific outcome. ... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal, Murine-Derived', 'Antibody Specificity', 'Female', 'Fluorescent Antibody Technique, Indirect', 'HeLa Cells', 'Histones', 'Humans', 'Hybridomas', 'Mice', 'Mice, Inbred C57BL', 'Peptide Fragments', 'Phosphoproteins', 'Rats', 'Rats, Inbred WKY'] | 23,607,347 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['G12.100'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Revision of the drinking water regulations]. | The revision the Drinking Water Regulations will come into effect on 01.11.2011. Surveillance authorities and owners of drinking water supply systems had hoped for simplifications and reductions because of the new arrangements. According to the official statement for the revision the legislature intended to create more... | ['Drinking Water', 'Environmental Monitoring', 'Germany', 'Guidelines as Topic', 'Water Pollutants, Chemical'] | 22,113,379 | [['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.542.315'], ['N04.761.700.350', 'N05.700.350'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The Staged Urethroplasty with Vascularised Scrotal Flap and Buccal Mucosa Graft after Failed Hypospadias Surgery: A Reliable Technique with a Novel Tool. | Background/Aims/Objectives: To report the outcome of staged urethroplasty with buccal mucosa and vascularised scrotal flap after failed hypospadias surgery.METHODS: n = 35.INCLUSION CRITERIA: destroyed urethral plate, deficient local skin, fistula and penile deviation. Five out of 35 patients also had a secondary proxi... | ['Adolescent', 'Adult', 'Child', 'Disease-Free Survival', 'Humans', 'Hypospadias', 'Male', 'Middle Aged', 'Mouth Mucosa', 'Penis', 'Postoperative Complications', 'Prospective Studies', 'Recurrence', 'Reoperation', 'Scrotum', 'Surgical Flaps', 'Time Factors', 'Treatment Failure', 'Urethra', 'Urethral Stricture', 'Urinar... | 28,285,314 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Orthodontic occlusal reconstruction after conservative treatment of unicystic ameloblastoma in an adolescent patient: 10-year follow-up. | Conservative treatment of an ameloblastoma often requires an occlusal reconstruction. In this article, we report the successful interdisciplinary treatment of a 14-year-old girl with a unicystic ameloblastoma in the mandible. One year after the marsupialization, enucleation with bone curettage was performed with extrac... | ['Adolescent', 'Ameloblastoma', 'Female', 'Follow-Up Studies', 'Humans', 'Malocclusion, Angle Class II', 'Mandibular Neoplasms', 'Occlusal Splints', 'Open Bite', 'Palatal Obturators', 'Tooth, Impacted'] | 23,992,819 | [['M01.060.057'], ['C04.557.695.065'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494.630'], ['C04.588.149.721.450.583', 'C05.116.231.754.450.583', 'C05.500.499.583', 'C05.500.607.442', 'C07.320.515.583', 'C07.320... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stage-specific differences of a perhaps signal-transferring system in Leishmania donovani. | There are stage-specific differences of adenosine 5'-monophosphate (AMP)-catabolizing reactions in amastigote and promastigote Leishmania donovani cells: 1. the pH-optimum of nucleotidase activity is 9.2 in amastigote cells and 5.4 in promastigote cells, 2. adenosine, product of the nucleotidase reaction, is metabolize... | ['Adenosine Monophosphate', 'Animals', 'Cell Membrane', 'Cricetinae', 'Hydrogen-Ion Concentration', 'Leishmania', 'Nucleotidases'] | 6,262,957 | [['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['B01.050'], ['A11.284.149'], ['B01.050.150.900.649.313.992.635.075.250'], ['G02.300'], ['B01.268.475.868.488'], ['D08.811.277.352.650.600']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparing transplant glomerulopathy in the absence of C4d deposition and donor-specific antibodies to chronic antibody-mediated rejection. | INTRODUCTION: Transplant glomerulopathy (TG) is the characteristic lesion of chronic antibody-mediated rejection (AMR). However, in some patients presents with no circulating HLA antibodies or C4d positivity.AIM: Patients with TG accomplishing criteria for chronic AMR were compared to patients with isolated TG.PATIENTS... | ['Adult', 'Chronic Disease', 'Complement C4b', 'Female', 'Fluorescent Antibody Technique', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Glomerulonephritis', 'Graft Rejection', 'Graft Survival', 'Humans', 'Immunoenzyme Techniques', 'Isoantibodies', 'Kidney Failure, Chronic', 'Kidney Function Tests', 'Kidney Trans... | 25,103,874 | [['M01.060.116'], ['C23.550.291.500'], ['D12.776.124.486.274.350.260'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.30... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Population-based analysis of arteriovenous malformation treatment. | OBJECT: The author sought to describe overall management data on cerebral arteriovenous malformations (AVMs) and to focus the actuarial need for different treatment modalities on a population-based scale. Such data would seem important in the planning of regional or national multimodality strategies for the treatment o... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cerebral Hemorrhage', 'Child', 'Embolization, Therapeutic', 'Female', 'Hematoma', 'Humans', 'Intracranial Arteriovenous Malformations', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Neurosurgical Procedures', 'Radiosurgery', 'Retrospective Studies', 'Rupture, S... | 11,596,958 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['M01.060.406'], ['E02.520.360', 'E02.926.500'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.520', 'C10.500.190.500', 'C... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is capitonnage unnecessary in the surgery of intact pulmonary hydatic cyst? | BACKGROUND: Hydatid disease, a parasitosis, is still an important health problem in Turkey. Surgery is the choice of treatment for pulmonary hydatid cyst. In this study, cystotomy and capitonnage were compared to cystotomy.METHODS: Fifty-nine patients with 70 pulmonary intact hydatid cysts were surgically treated betwe... | ['Adult', 'Echinococcosis, Pulmonary', 'Female', 'Humans', 'Male', 'Thoracic Surgical Procedures', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 14,725,704 | [['M01.060.116'], ['C01.610.335.190.396.480', 'C01.610.582.314', 'C01.748.450.314', 'C08.381.517.314', 'C08.730.450.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A rare case of partial diaphragmatic agenesis with thoracic liver herniation and anteriorly displaced intrathoracic kidney in an adult diagnosed by displaced diaphragmatic crus. | Diaphragmatic agenesis is a rare anomaly and usually occurs in the early neonatal period. Its exact pathogenesis from the embryologic viewpoint is still unknown. Its presentation in adulthood is extremely rare, with only 7 cases of hemidiaphragmatic agenesis reported in adults. They are usually associated with herniati... | ['Adult', 'Colon', 'Diaphragm', 'Female', 'Hernias, Diaphragmatic, Congenital', 'Humans', 'Kidney', 'Liver', 'Radiography', 'Thorax'] | 23,483,266 | [['M01.060.116'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['A02.633.567.900.300'], ['C16.131.433', 'C23.300.707.960.500.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A03.620'], ['E01.370.350.700'], ['A01.923.761']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
3D phase contrast MRI in models of human airways: Validation of computational fluid dynamics simulations of steady inspiratory flow. | BACKGROUND: Knowledge of airflow patterns in the large airways is of interest in obstructive airways disease and in the development of inhaled therapies. Computational fluid dynamics (CFD) simulations are used to study airflow in realistic airway models but usually need experimental validation.PURPOSE: To develop MRI-b... | ['Case-Control Studies', 'Computer Simulation', 'Humans', 'Hydrodynamics', 'Imaging, Three-Dimensional', 'Larynx', 'Lung', 'Magnetic Resonance Imaging', 'Models, Biological', 'Phantoms, Imaging', 'Regression Analysis', 'Reproducibility of Results', 'Software', 'Trachea', 'Water'] | 29,630,757 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.342'], ['E01.370.350.400', 'L01.224.308.410'], ['A04.329'], ['A04.411'], ['E01.370.350.825.500'], ['E05.599.395'], ['E07.671'], ['E05.318.740.750', 'N05.715.360.750.695... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A theory-based evaluation of a community-based funding scheme in a disadvantaged suburban city area. | Community-driven development (CDD) initiatives frequently involve funding schemes which are aimed at channelling financial investment into local need and fostering community participation and engagement. This exploratory study examined, through a program theory approach, the design and implementation of a small-scale, ... | ['Community Participation', 'Financing, Organized', 'Humans', 'Ireland', 'Organizational Case Studies', 'Poverty Areas', 'Program Development', 'Program Evaluation', 'Social Change', 'Suburban Population', 'Vulnerable Populations'] | 25,933,408 | [['N02.421.143.212', 'N03.540.245.360'], ['N03.219.521'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.467', 'Z01.639.587'], ['N03.349.380.710', 'N05.715.360.455'], ['I01.880.853.996.535.550', 'N01.824.600.550'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['I01.076.201.450.776', '... | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The somatostatin receptor-targeted radiotherapeutic [90Y-DOTA-DPhe1, Tyr3]octreotide (90Y-SMT 487) eradicates experimental rat pancreatic CA 20948 tumours. | Somatostatin receptor-expressing tumours are potential targets for therapy with radiolabelled somatostatin analogues. We have synthesized a number of such analogues in the past and identified [DOTA-dPhe1, Tyr3]octreotide (SMT 487) as the most promising candidate molecule because of its advantageous properties in cellul... | ['Animals', 'Humans', 'Octreotide', 'Pancreatic Neoplasms', 'Polymerase Chain Reaction', 'Radiopharmaceuticals', 'Rats', 'Rats, Inbred Lew', 'Receptors, Somatostatin', 'Tissue Distribution', 'Yttrium Radioisotopes'] | 9,662,587 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.345.566.650', 'D12.644.641.650'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['E05.393.620.500'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.410.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transesophageal Endoscopic Ultrasound-guided Fine Needle Aspiration for the Diagnosis of a Lung Nodule that Was Non-abutting on CT. | An 80-year-old man presented with a right side lung tumor. The tumor was not abutting the bronchus or chest wall; thus, endobronchial ultrasound (EBUS) and CT-guided biopsy were considered to be technically difficult. We therefore attempted endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Although the nod... | ['Aged, 80 and over', 'Endoscopic Ultrasound-Guided Fine Needle Aspiration', 'Esophagus', 'Humans', 'Lung Neoplasms', 'Male', 'Neoplasm Staging'] | 28,924,107 | [['M01.060.116.100.080'], ['E01.370.225.500.384.100.119.500.500', 'E01.370.225.500.384.100.370.500', 'E01.370.225.998.054.119.500.500', 'E01.370.225.998.054.370.500', 'E01.370.350.850.855.500', 'E01.370.388.100.100.500.500', 'E01.370.388.100.370.500', 'E04.074.119.500.500', 'E04.074.370.500', 'E04.502.890.500', 'E05.20... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Laparoscopic transumbilical cholecystectomy: surgical technique. | BACKGROUND: Laparoscopic cholecystectomy is generally performed using 4 ports by transperitoneal access. Recent developments regarding laparoscopic surgery have been directed toward reducing the size or number of ports to achieve the goal of minimally invasive surgery, by minilaparoscopy, natural orifice access, and th... | ['Adult', 'Biliary Tract Diseases', 'Cholecystectomy, Laparoscopic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Treatment Outcome', 'Umbilicus'] | 20,042,128 | [['M01.060.116'], ['C06.130'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['A01.923.047.849']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of FK506 on glycemic response as assessed by the hyperglycemic clamp technique. | We studied seven nondiabetic subjects with the autoimmune diseases psoriasis, multiple sclerosis, and primary biliary sclerosis who were to receive FK506 as experimental immunotherapy. All subjects underwent two standard oral glucose tolerance tests and two 180-min hyperglycemic clamps immediately before and 10 weeks a... | ['Blood Glucose', 'Glucose Clamp Technique', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Insulin Secretion', 'Tacrolimus'] | 7,542,815 | [['D09.947.875.359.448.500'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['D02.540.505.8... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Baclofen, a GABAB receptor agonist, inhibits human hepatocellular carcinoma cell growth in vitro and in vivo. | Gamma aminobutyric acid (GABA) has been reported to affect cancer development, but the activation of its type B receptor (GABABR) has shown contradictory effects on the progress of human carcinoma. In this study, we investigated the antitumor effect of the GABABR agonist baclofen (Bac) on growth of human hepatocellular... | ['Animals', 'Baclofen', 'Carcinoma, Hepatocellular', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cyclic AMP', 'Cyclin-Dependent Kinase Inhibitor p21', 'GABA Agonists', 'GABA-B Receptor Agonists', 'Humans', 'Liver Neoplasms, Experimental', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'RNA, Messenger... | 18,222,491 | [['B01.050'], ['D02.241.081.114.500.350.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patients' stories: science, clinical facts or fairy tales? | OBJECTIVE: To explore potentials and attributes of the qualitative research interview as a tool for acquiring knowledge about illness.DESIGN: A qualitative approach, comparing knowledge about consultations originating from 1) data from interviews with immigrant female patients, and 2) evaluative data from registration ... | ['Adult', 'Communication Barriers', 'Emigration and Immigration', 'Ethnic Groups', 'Female', 'Humans', 'Interviews as Topic', 'Medical History Taking', 'Middle Aged', 'Norway', 'Pakistan', 'Referral and Consultation'] | 7,777,737 | [['M01.060.116'], ['L01.143.230'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E01.370.510'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Prognostic value of cardiac I-123 metaiodobenzylguanidine imaging in patients with non-insulin-dependent diabetes mellitus. | BACKGROUND: 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy is a useful tool for diagnosing cardiac autonomic neuropathy (CAN) in non-insulin-dependent diabetes mellitus (NIDDM). However, the long-term prognostic value for cardiac events or mortality in NIDDM has not been clarified.METHODS AND RESULTS: We i... | ['3-Iodobenzylguanidine', 'Autonomic Nervous System Diseases', 'Comorbidity', 'Diabetes Mellitus, Type 2', 'Diabetic Neuropathies', 'Female', 'Heart Diseases', 'Humans', 'Incidence', 'Japan', 'Male', 'Middle Aged', 'Prognosis', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Reproducibility of Results', 'Risk Assessme... | 16,464,715 | [['D02.078.370.510', 'D02.455.426.559.389.454.300', 'D02.455.526.581.496.300'], ['C10.177'], ['N05.715.350.225', 'N06.850.490.687'], ['C18.452.394.750.149', 'C19.246.300'], ['C10.668.829.300', 'C19.246.099.937'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Phonological network fluency identifies phonological restructuring through mental search. | We investigated network principles underlying mental search through a novel phonological verbal fluency task. Post exclusion, 95 native-language Mandarin speakers produced as many items that differed by a single lexical tone as possible within one minute. Their verbal productions were assessed according to several nove... | ['Adolescent', 'Adult', 'Female', 'Hong Kong', 'Humans', 'Language Tests', 'Male', 'Multilingualism', 'Verbal Behavior', 'Young Adult'] | 31,690,737 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['L01.559.423.452'], ['F01.145.209.908'], ['M01.060.116.815']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Pelvic MRI findings in relapsed prostate cancer after radical prostatectomy. | PURPOSE/OBJECTIVE: Little is known about the clinical impact of using multiparametric MRI to plan early salvage radiotherapy after radical prostatectomy. We aimed to evaluate the incidence and location of recurrence based on pelvic multiparametric MRI findings and to identify clinical variables predictive of positive i... | ['Aged', 'Aged, 80 and over', 'Humans', 'Image Interpretation, Computer-Assisted', 'Lymphatic Metastasis', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pelvis', 'Prostatectomy', 'Prostatic Neoplasms', 'Radiotherapy', 'Retrospective Studies', 'Salvage Therapy'] | 26,704,623 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['A01.923.600'], ['E04.950.774.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Increased circulating trimethylamine N-oxide contributes to endothelial dysfunction in a rat model of chronic kidney disease. | Chronic kidney disease (CKD) is strongly associated with increased cardiovascular risk. Impaired endothelial function, a key initiating step in the pathogenesis of cardiovascular disease, has been reported in patients with CKD, but the mechanisms responsible for endothelial dysfunction in CKD remain elusive. Emerging e... | ['Animals', 'Biomarkers', 'Cytokines', 'Endothelium, Vascular', 'Male', 'Methylamines', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species', 'Renal Insufficiency, Chronic', 'Vascular Diseases'] | 29,247,650 | [['B01.050'], ['D23.101'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.092.668'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D01.339.431', 'D01.650.775'], ['C12.777.419.780.750', 'C13.351.968.419.780.750'], ['C... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Necessity of a uniform start for scanning after FDG injection in brain PET study. | UNLABELLED: The authors' goal was to show the importance of starting scanning at a uniform time after F-18 fluorodeoxyglucose injection in positron emission tomography (PET) brain study.METHOD: Fifteen healthy normal subjects underwent FDG-PET to obtain glucose metabolic images starting 60 min and 70 min after FDG inje... | ['Adult', 'Artifacts', 'Brain', 'Fluorodeoxyglucose F18', 'Humans', 'Image Enhancement', 'Injections, Intraventricular', 'Male', 'Metabolic Clearance Rate', 'Middle Aged', 'Positron-Emission Tomography', 'Radiopharmaceuticals', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Time Factors'] | 16,856,579 | [['M01.060.116'], ['E05.047'], ['A08.186.211'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E02.319.267.530.550'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['M01.060.116.630'], ['E01.370.350.350.800.700', 'E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Association study of three polymorphisms of kinesin light-chain 1 gene with Alzheimer's disease. | The transport of amyloid precursor protein is mediated through its interaction with kinesin light-chain 1 (KNS2). We hypothesized that kinesin light-chain dysfunction might be involved in the pathogenesis of Alzheimer's disease (AD). To assess the physiological relevance of an allelic variation in the KNS2 gene, the as... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Chi-Square Distribution', 'Confidence Intervals', 'Female', 'Gene Frequency', 'Humans', 'Male', 'Microtubule-Associated Proteins', 'Middle Aged', 'Odds Ratio', 'Polymorphism, Single Nucleotide'] | 15,364,413 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['G05.330'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Use of atracurium in cardiac surgery involving cardiopulmonary bypass with induced hypothermia. | Atracurium was administered by infusion to 12 anaesthetized patients undergoing cardiac surgery with cardiopulmonary bypass and induced hypothermia. Following an initial bolus dose of 0.6 mg kg-1, an infusion of atracurium was continued at an average rate of 0.0066 +/- 0.0003 mg kg-1 min-1 (0.4 mg kg-1 h-1) which was s... | ['Adult', 'Aged', 'Atracurium', 'Cardiopulmonary Bypass', 'Heart Valve Prosthesis', 'Humans', 'Hypothermia, Induced', 'Infusions, Parenteral', 'Isoquinolines', 'Middle Aged', 'Muscle Contraction', 'Neuromuscular Blocking Agents', 'Time Factors'] | 6,547,844 | [['M01.060.116'], ['M01.060.116.100'], ['D03.633.100.531.085.061'], ['E04.292.413'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['E02.319.267.510'], ['D03.633.100.531'], ['M01.060.116.630'], ['G11.427.494'], ['D27.505.696.663.700.710'], ['G01.910.857']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hypothalamic projections of renal afferent nerves in the cat. | In 10 cats anaesthetized with chloralose the electrical activity of spontaneously active hypothalamic units was recorded for changes in discharge rate during electrical stimulation of renal afferent nerves. The discharge rate of 141 single units was altered by stimulation of either the ipsilateral or contralateral rena... | ['Afferent Pathways', 'Animals', 'Cats', 'Female', 'Hypothalamus', 'Kidney', 'Male', 'Water-Electrolyte Balance'] | 7,417,886 | [['A08.612.220'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A05.810.453'], ['G02.111.635.500', 'G03.615.500', 'G07.410.810.500']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer. | This issue of Molecular Medicine contains 14 original research reports and state-of-the-art reviews on histone deacetylase inhibitors (HDACi's), which are being studied in models of a broad range of diseases not related to the proapoptotic properties used to treat cancer. The spectrum of these diseases responsive to HD... | ['Anti-Inflammatory Agents', 'Arthritis', 'HIV Infections', 'Histone Deacetylase Inhibitors', 'Humans', 'Neoplasms', 'Neurodegenerative Diseases'] | 21,556,484 | [['D27.505.954.158'], ['C05.550.114'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['D27.505.519.389.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C10.574']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laboratory studies on salmonella-contaminated cheese involved in a major outbreak of gastroenteritis. | A major outbreak of gastroenteritis was traced to Cheddar cheese contaminated with Salmonella typhimurium. There were no significant differences in pH values of the contaminated (mean pH 5.31) and non-contaminated (mean pH 5.39) cheese. The isolation rates of Salm. typhimurium were about the same when cheese samples we... | ['Animals', 'Canada', 'Cheese', 'Disease Outbreaks', 'Food Microbiology', 'Gastroenteritis', 'Humans', 'Hydrogen-Ion Concentration', 'Salmonella Food Poisoning', 'Salmonella typhimurium'] | 3,531,140 | [['B01.050'], ['Z01.107.567.176'], ['G07.203.200.500.444', 'G07.203.300.350.300.444', 'J02.350.500.444', 'J02.500.350.300.444'], ['N06.850.290'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['C06.405.205'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Functional Outcomes After the Prosthetic Training Phase of Rehabilitation After Dysvascular Lower Extremity Amputation. | OBJECTIVE: To describe physical function outcomes and modes of physical therapy intervention for a cohort of patients with dysvascular lower extremity amputation (LEA) during the prosthetic training phase of rehabilitation.DESIGN: A retrospective cohort study.SETTING: Physical rehabilitation clinics at a Veterans Affai... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amputation', 'Artificial Limbs', 'Dependent Ambulation', 'Female', 'Gait', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Peripheral Vascular Diseases', 'Physical Therapy Modalities', 'Recovery of Function', 'Retrospective Studies'] | 25,978,948 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.080'], ['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['G11.427.410.568.900.500'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['H01.770.644.14... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Localized reactive angioendotheliomatosis. | We present a unique case of a woman with multiple painful dermal lesions localized to the left upper quadrant of the body. Histological investigation revealed microvascular thrombosis with capillary-wall proliferation. Further investigation revealed a very high anticardiolipin IgG titre and a left subclavian stenosis, ... | ['Antibodies, Anticardiolipin', 'Aortic Valve Stenosis', 'Female', 'Hemangioendothelioma', 'Humans', 'Middle Aged', 'Neoplasms, Vascular Tissue', 'Protein C Deficiency', 'Thrombosis'] | 17,004,988 | [['D12.776.124.486.485.114.323.210.100', 'D12.776.124.790.651.114.323.210.100', 'D12.776.377.715.548.114.323.210.100'], ['C14.280.484.048.750', 'C14.280.955.249'], ['C04.557.645.375.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.645'], ['C15.378.100.100.690', 'C15.378.147.880', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Purification of the catalyst of adenylate cyclase. | The catalytic moiety of hormone-sensitive adenylate cyclase has been purified from bovine brain. It is isolated largely without its guanine nucleotide-binding regulatory protein, Gs, by affinity chromatography on 7-O-hemisuccinyldeacetylforskolin-agarose. It appears to be a single polypeptide which migrates on sodium d... | ['Adenylyl Cyclases', 'Animals', 'Calmodulin', 'Cattle', 'Chromatography, Affinity', 'Chromatography, Agarose', 'Colforsin', 'Enzyme Activation', 'GTP-Binding Proteins', 'Lectins', 'Membrane Proteins', 'Wheat Germ Agglutinins'] | 3,080,431 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.170'], ['E05.196.181.400.250.200'], ['D02.455.849.291.300'], ['G02.111.263', 'G03.328'], ['D08.811.277.040.33... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fatigue at sea in Swedish shipping-a field study. | BACKGROUND: Today many merchant ships sail with only two nautical officers, working a shift schedule of 6 hr on and 6 hr off. There are concerns that such a shift schedule is related to fatigue. However, little data exist from onboard studies of seafarers.METHODS: Data were collected on board 13 ships. Fifteen particip... | ['Adult', 'Fatigue', 'Female', 'Humans', 'Male', 'Middle Aged', 'Ships', 'Sleep', 'Sweden', 'Time Factors', 'Wakefulness', 'Work Schedule Tolerance'] | 20,187,001 | [['M01.060.116'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.937.817'], ['F02.830.855', 'G11.561.803'], ['Z01.542.816.500'], ['G01.910.857'], ['F02.830.104.821', 'G11.561.035.738'], ['I03.946.225.375', 'N04.452.677.650.375']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Myosin heavy chain kinase inactivated by Ca2+/calmodulin from aggregating cells of Dictyostelium discoideum. | Soluble myosin heavy chain kinases (MHC kinases) were partially purified from growth phase and aggregation-competent cells of Dictyostelium discoideum. In the aggregation-competent cells, two MHC kinases were distinguishable. One of these enzymes, called MHC kinase II, was inactivated by Ca2+ and calmodulin in a highly... | ['Calcium', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Calmodulin', 'Cell Aggregation', 'Chemotaxis', 'Cyclic AMP', 'Dictyostelium', 'Phosphorylation', 'Phosphothreonine', 'Phosphotransferases', 'Protozoan Proteins'] | 6,313,344 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['G04.198.251'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of cytomegalovirus colitis with endoscopic finding resembling Crohn's disease]. | Cytomegalovirus (CMV) colitis is common among immunocompromised patients, and often diagnosed by pathologic confirmation because it is associated with a diverse spectrum of clinical and endoscopic features. However, Crohn's disease has no definitive diagnostic criteria, but longitudinal ulcers and cobble stone appearan... | ['Aged, 80 and over', 'Antiviral Agents', 'Colitis', 'Colonoscopy', 'Crohn Disease', 'Cytomegalovirus Infections', 'Ganciclovir', 'Humans', 'Immunohistochemistry', 'Injections, Intravenous', 'Male', 'Tomography, X-Ray Computed'] | 22,544,028 | [['M01.060.116.100.080'], ['D27.505.954.122.388'], ['C06.405.205.265', 'C06.405.469.158.188'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['C01.925.256.466.245'], ['D03.633.100.759.758.399.454.250.300'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Capsule-splitting phenomenon during capsulorhexis in pseudoexfoliation. | We present the case of a 78-year-old white woman with a 2+ nuclear sclerotic cataract and pseudoexfoliation syndrome who had cataract extraction with intraocular lens implantation. The initial continuous curvilinear capsulorhexis (CCC) was performed with a cystotome. Due to unusual tearing characteristics, there was co... | ['Aged', 'Capsulorhexis', 'Cataract', 'Cataract Extraction', 'Coloring Agents', 'Exfoliation Syndrome', 'Female', 'Humans', 'Intraoperative Complications', 'Lens Capsule, Crystalline', 'Staining and Labeling', 'Trypan Blue'] | 26,100,956 | [['M01.060.116.100'], ['E04.540.825.249.352'], ['C11.510.245'], ['E04.540.825.249'], ['D27.720.233'], ['C11.941.375.285'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['A09.371.060.500.155'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670'], ['D0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regional volumetric coronary blood flow measurement by digital angiography: in vivo validation. | RATIONALE AND OBJECTIVES: There are well-known limitations to the use of visual estimation to assess the severity of coronary artery disease and luminal stenosis. This is especially true in the case of an intermediate coronary lesion (30%-70% diameter stenosis), where coronary arteriography is very limited in distingui... | ['Absorptiometry, Photon', 'Angiography, Digital Subtraction', 'Animals', 'Blood Flow Velocity', 'Blood Volume', 'Contrast Media', 'Coronary Angiography', 'Coronary Circulation', 'Swine', 'Video Recording'] | 15,217,593 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.188.130', 'G09.330.380.092'], ['D27.505.259.500', 'D27.720.259'], ['E01.370... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence of iron-deficiency anaemia and risk factors in 1010 adolescent girls from rural Maharashtra, India: a cross-sectional survey. | OBJECTIVE: Iron-deficiency anaemia (IDA) is the most common nutritional disorder observed in adolescent girls in India. Our aim was to investigate the prevalence and risk factors associated with IDA in rural Maharashtra, India, to address current evidence gaps.STUDY DESIGN: Cross-sectional survey.METHODS: The study rec... | ['Adolescent', 'Anemia, Iron-Deficiency', 'Cross-Sectional Studies', 'Diet', 'Female', 'Fruit', 'Hemoglobins', 'Humans', 'India', 'Logistic Models', 'Nutrition Surveys', 'Nutritional Status', 'Prevalence', 'Risk Factors', 'Rural Health', 'Rural Population', 'Socioeconomic Factors', 'Surveys and Questionnaires'] | 27,592,006 | [['M01.060.057'], ['C15.378.071.196.300', 'C18.452.565.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology,... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Health Effects of Dietary Oxidized Tyrosine and Dityrosine Administration in Mice with Nutrimetabolomic Strategies. | This study aims to investigate the health effects of long-term dietary oxidized tyrosine (O-Tyr) and its main product (dityrosine) administration on mice metabolism. Mice received daily intragastric administration of either O-Tyr (320 ìg/kg body weight), dityrosine (Dityr, 320 ìg/kg body weight), or saline for consecut... | ['Animals', 'Female', 'Liver', 'Metabolomics', 'Mice', 'Oxidation-Reduction', 'Tyrosine'] | 28,742,334 | [['B01.050'], ['A03.620'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.700', 'G03.295.531'], ['D12.125.072.050.875']] | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Lipid composition and fertility of human ejaculate]. | The morpho-functional indexes of ejaculates from 35 healthy and 145 infertile men were studied. The depression of functional sperm activity was found in the majority of infertile men. Phospholipid analysis of whole ejaculates from 12 healthy and 35 infertile subjects was performed. It was shown that inorganic phosphoru... | ['Fatty Acids', 'Fertility', 'Humans', 'Lipids', 'Lysophosphatidylcholines', 'Lysophospholipids', 'Male', 'Phosphatidylinositols', 'Phospholipids', 'Phosphorus', 'Semen'] | 8,284,822 | [['D10.251'], ['G08.686.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['D10.570.755.375.760.550.550'], ['D10.570.755.375.760.550'], ['D10.570.755.375.760.400.942'], ['D10.570.755'], ['D01.268.666'], ['A12.200.732']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simulation of chaotic EEG patterns with a dynamic model of the olfactory system. | The main parts of the central olfactory system are the bulb (OB), anterior nucleus (AON), and prepyriform cortex (PC). Each part consists of a mass of excitatory or inhibitory neurons that is modelled in its noninteractive state by a 2nd order ordinary differential equation (ODE) having a static nonlinearity. The model... | ['Animals', 'Brain', 'Central Nervous System', 'Electroencephalography', 'Mathematics', 'Models, Neurological', 'Neurons', 'Olfactory Bulb', 'Olfactory Pathways'] | 3,593,783 | [['B01.050'], ['A08.186.211'], ['A08.186'], ['E01.370.376.300', 'E01.370.405.245'], ['H01.548'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['A08.186.211.200.885.388'], ['A08.186.211.180.699', 'A08.612.220.640']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Assessment of nutritional status and of intestinal absorption in asymptomatic patients infected with the human immunodeficiency virus (HIV) with and without chronic hepatitis]. | OBJECTIVE: To compare nutritional status and intestinal absorption in asymptomatics HIV patients co-infected or not with hepatitis C virus.MATERIAL AND METHODS: 15 patients (9 men and 6 women) HIV seropositive in A1-A2 stage were classified in two groups, A were asymptomatics HIV patients and B were asymptomatic HIV pa... | ['Data Interpretation, Statistical', 'Female', 'HIV Infections', 'HIV Seropositivity', 'Hepatitis C, Chronic', 'Humans', 'Intestinal Absorption', 'Malabsorption Syndromes', 'Male', 'Nutritional Status', 'Xylose'] | 16,913,214 | [['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The Linking Lives health education program: a randomized clinical trial of a parent-based tobacco use prevention program for african american and latino youths. | OBJECTIVES: We evaluated the effectiveness of a parent-based add-on component to a school-based intervention to prevent cigarette smoking among African American and Latino middle school youths.METHODS: Mother-adolescent dyads (n=1386) were randomly assigned to 2 groups: (1) a school-based smoking-prevention interventio... | ['Adolescent', 'Adolescent Behavior', 'African Americans', 'Female', 'Health Education', 'Hispanic Americans', 'Humans', 'Male', 'Mother-Child Relations', 'New York City', 'Regression Analysis', 'Smoking', 'Smoking Prevention', 'Treatment Outcome'] | 20,634,469 | [['M01.060.057'], ['F01.145.022'], ['M01.686.508.100.100', 'M01.686.754.100'], ['I02.233.332', 'N02.421.726.407'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290.170'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', 'Z01.433.741'], ['E05.318.740.750', 'N05.71... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Breast Cancer in Transgender Veterans: A Ten-Case Series. | All known cases of breast cancer in patients with a diagnosis consistent with transgender identification were identified in the Veterans Health Administration (1996-2013). Ten cases were confirmed: seven birth sex females and three birth sex males. Of the three birth sex males, two identified as gender dysphoric male-t... | ['Adult', 'Aged', 'Breast Neoplasms, Male', 'Early Detection of Cancer', 'Fatal Outcome', 'Female', 'Gender Dysphoria', 'Humans', 'Male', 'Middle Aged', 'Transgender Persons', 'Veterans'] | 26,790,021 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180.260', 'C17.800.090.500.260'], ['E01.390.500'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['F03.835.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.777.500'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of the frequency of Pneumocystis jirovecii occurrence in a group of children hospitalized for acute respiratory infections. | Primary infection with Pneumocystis jirovecii in small children may cause inflammation of the respiratory tract which requires hospitalization. Lack of characteristic clinical symptoms makes it impossible to recognize P. jirovecii infections without performing laboratory analyses. Nasopharyngeal swabs from 70 children ... | ['Child, Preschool', 'Coinfection', 'Comorbidity', 'Cross Infection', 'Diagnosis, Differential', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Pneumocystis carinii', 'Pneumonia, Pneumocystis', 'Poland', 'Respiratory Tract Infections'] | 21,682,093 | [['M01.060.406.448'], ['C01.218'], ['N05.715.350.225', 'N06.850.490.687'], ['C01.248', 'C23.550.291.875.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['M01.060.703.52... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A systematic review of studies measuring health-related quality of life of general injury populations: update 2010-2018. | BACKGROUND: Studies examining the impact of injury on health-related quality of life (HRQL) over time are necessary to understand the short- and long-term consequences of injury for population health. The aim of this systematic review was to provide an evidence update on studies that have measured HRQL over time in gen... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Disabled Persons', 'Female', 'Follow-Up Studies', 'Health Status Indicators', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Research Design', 'Wounds and Injuries', 'Young Adult'] | 32,471,430 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['M01.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)]. | Adult mongrel dogs were used. The posterior communicating artery was punctured with a fine needle and subarachnoid hemorrhage was produced, which simulated aneurysmal rupture in human. The cerebral basal arteries were constricted remarkably after the puncture. However this vasospasm disappeared in about 60-120 minutes.... | ['Animals', 'Autonomic Agents', 'Cerebral Arteries', 'Dogs', 'Ischemic Attack, Transient', 'Isoxsuprine', 'Methysergide', 'Papaverine', 'Phentolamine', 'Propranolol', 'Subarachnoid Hemorrhage', 'Sympathectomy', 'Sympathetic Nervous System'] | 1,239,688 | [['B01.050'], ['D27.505.696.663.050'], ['A07.015.114.228'], ['B01.050.150.900.649.313.750.250.216.200'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['D02.033.100.624.427', 'D02.033.755.624.427', 'D02.092.471.683.560'], ['D03.132.327.287.689', 'D03.633.400.439.689'], ['D03.132.098.666', 'D03.132.577.750', 'D03.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spinal myxopapillary ependymoma with Down syndrome: exploring an unusual association. | SUMMARY: In patients with Down syndrome, cancers like leukemia and testicular tumors are frequent, but association with central nervous system tumors is rare. Only 1 case of ependymoma has been observed as an incidental autopsy finding in a 19-week-old female fetus. We herein report the second case of ependymoma and th... | ['Adolescent', 'Combined Modality Therapy', 'Down Syndrome', 'Ependymoma', 'Female', 'Humans', 'Karyotyping', 'Remission Induction', 'Spinal Cord Neoplasms'] | 20,051,776 | [['M01.060.057'], ['E02.186'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['C04.557.465.625.600.380.290', 'C04.557.470.670.380.290', 'C04.557.580.625.600.380.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Can we differentiate minimally invasive adenocarcinoma and non-invasive neoplasms based on high-resolution computed tomography features of pure ground glass nodules? | OBJECTIVE: The purpose of our study was to assess the differentially diagnostic value of radiographic characteristics of pure ground glass nodules (GGNs) between minimally invasive adenocarcinoma and non-invasive neoplasm.METHODS: Sixty-seven pure GGNs (28 minimally invasive adenocarcinomas (MIA) and 39 pre-invasive le... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Tomography, X-Ray Computed'] | 28,683,126 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.727.645'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Symptomatic lithiasic biliary disease. Comparison between men and women undergoing cholecystectomy]. | A prospective survey was carried out in 205 males and 667 females who had their gallbladder removed for gallstone disease during 1989 at a general hospital in Chile. Females had a greater prevalence of disease with an earlier appearance of symptoms leading to surgery at a younger age. In contrast, males developed a mor... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Cholecystectomy', 'Cholelithiasis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies'] | 9,723,091 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.120.172'], ['C06.130.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia. | Antley-Bixler syndrome (ABS) is a rare multiple anomaly syndrome comprising radiohumeral synostosis, bowed femora, fractures of the long bones, premature fusion of the calvarial sutures, severe midface hypoplasia, proptosis, choanal atresia, and, in some, ambiguous genitalia. Of fewer than 40 patients described to date... | ['Abnormalities, Multiple', 'Craniosynostoses', 'Cytochrome P-450 Enzyme System', 'DNA Mutational Analysis', 'Fatal Outcome', 'Female', 'Fetal Death', 'Genitalia', 'Humans', 'Infant', 'Male', 'Oxidoreductases', 'Receptor Protein-Tyrosine Kinases', 'Receptor, Fibroblast Growth Factor, Type 2', 'Receptors, Fibroblast Gro... | 12,116,245 | [['C16.131.077'], ['C05.116.099.370.894.232', 'C05.660.207.240', 'C05.660.906.364', 'C16.131.621.207.240', 'C16.131.621.906.364'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['E05.393.760.700.300'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.30... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition and kinetic alterations by excess free ATP and ADP of the ATP diphosphohydrolase activity (EC 3.6.1.5) from rat blood platelets. | ATP diphosphohydrolase (EC 3.6.1.5) catalyzes the hydrolysis of diphospho- and triphosphonucleosides and is activated by divalent cations. The enzyme described in rat blood platelets hydrolyzes Ca(2+)-ATP and Ca(2+)-ADP with a high affinity for these Ca(2+)-nucleotide complexes as substrates. In the present paper, we d... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Animals', 'Apyrase', 'Binding Sites', 'Blood Platelets', 'Calcium', 'Cations, Divalent', 'Enzyme Activation', 'Kinetics', 'Male', 'Rats', 'Rats, Wistar', 'Substrate Specificity'] | 7,773,186 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.277.040.050'], ['G02.111.570.120'], ['A11.118.188', 'A15.145.229.188'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gender differences in restricted and repetitive behaviors and interests in youth with autism. | Previous work has found gender differences in restricted and repetitive behaviors and interests (RRBI) for autism spectrum disorder (ASD). Compared to girls, affected boys have increased stereotyped and restricted behaviors; however much less is known about gender differences in other areas of RRBI. This study aims to ... | ['Adolescent', 'Autism Spectrum Disorder', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Sex Factors', 'Stereotyped Behavior'] | 30,561,911 | [['M01.060.057'], ['F03.625.164.113'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.896']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Commonly used diagnostic criteria for pelvic inflammatory disease have poor sensitivity for plasma cell endometritis. | BACKGROUND: The majority of women with tubal damage do not have a history of acute pelvic inflammatory disease. The prevalence of upper genital tract inflammation was evaluated in women deemed not to have pelvic inflammatory disease by common diagnostic criteria.GOAL OF THIS STUDY: To compare clinical signs and laborat... | ['Adolescent', 'Adult', 'Biopsy', 'Case-Control Studies', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Endometritis', 'Female', 'Gonorrhea', 'Humans', 'Pelvic Inflammatory Disease', 'Plasma Cells', 'Sensitivity and Specificity', 'Uterine Cervicitis', 'Vaginosis, Bacterial'] | 8,578,403 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Catalysis with phosphine-containing amino acids in various "turn" motifs. | We have been actively involved in the development of parallel approaches for the discovery of phosphine ligands. Our approach has been based on the incorporation of phosphine-containing amino acids into peptide sequences that are designed to have stable secondary structures. We have examined helical and turn secondary ... | ['Amino Acid Sequence', 'Amino Acids', 'Catalysis', 'Ligands', 'Models, Molecular', 'Oligopeptides', 'Phosphines', 'Protein Structure, Secondary', 'Stereoisomerism'] | 15,527,293 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['G02.130'], ['D27.720.470.480'], ['E05.599.595'], ['D12.644.456'], ['D01.695.525', 'D02.705.621'], ['G02.111.570.820.709.600'], ['G02.607.445.682']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation. | The cholinergic agonist carbachol (1.1 mM) and the adenosinergic agonist cyclohexyladenosine (0.1 mM) were microinjected (60 nl) into the region of the caudal, oral pontine reticular formation of the rat. Local intracerebral infusion of each receptor agonist resulted in significant, long-lasting (at least 8 h) elevatio... | ['Adenosine', 'Animals', 'Atropine', 'Brain Mapping', 'Carbachol', 'Infusions, Parenteral', 'Male', 'Microinjections', 'Muscarinic Antagonists', 'Pons', 'Purinergic P1 Receptor Agonists', 'Purinergic P1 Receptor Antagonists', 'Rats', 'Reticular Formation', 'Sleep', 'Sleep, REM', 'Theophylline', 'Time Factors', 'Wakeful... | 9,692,741 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D02.092.877.883.333.115',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter. | We have identified oncogene-responsive sequences in the human c-fos promoter that mediate induction of transcription by several nonnuclear oncoproteins and the tumor promoter TPA. These sequences are regulated in a cell-specific manner. (i) In NIH 3T3 cells, the CArG box of the c-fos promoter is sufficient to mediate a... | ['Base Sequence', 'Gene Expression Regulation, Neoplastic', 'Genes, ras', 'HeLa Cells', 'Humans', 'Molecular Sequence Data', 'Mutation', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins c-fos', 'Proto-Oncogenes', 'Recombinant Fusion Proteins', 'Regulatory Sequences, Nucleic Acid', 'Tetradecanoylphorbol Acetate'] | 1,922,053 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.370'], ['G05.360.340.024.340.375.500.791.550'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G05.365.590'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Surgical treatment of pulmonary emphysema]. | The paper presents the results of surgical treatment of 139 patients with different forms of pulmonary emphysema and its variations complicated with spontaneous pneumothorax or development of bullae of different sizes and patients with congenital lobar and unilateral emphysema (McLeod syndrome). The pathophysiological ... | ['Adolescent', 'Adult', 'Follow-Up Studies', 'Humans', 'Lung', 'Lung Volume Measurements', 'Middle Aged', 'Pleura', 'Pneumonectomy', 'Pulmonary Emphysema'] | 3,765,713 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E01.370.386.700.485'], ['M01.060.116.630'], ['A04.716', 'A10.615.789.736'], ['E04.620', 'E04.928.600.600'], ['C08.381.495.389.750'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Myoarthropathies of the masticatory system. Diagnosis]. | Guidelines are presented for the diagnosis of myoarthropathy of the masticatory system. Attention should especially be paid to the history of the patient and the importance of a careful clinical inspection. | ['Humans', 'Stomatognathic System', 'Temporomandibular Joint Dysfunction Syndrome'] | 2,639,259 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A14'], ['C05.500.607.221.897.897', 'C05.550.905.905', 'C05.651.243.897.897', 'C05.651.550.905', 'C07.320.610.291.897.897', 'C07.678.949']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Xanthine oxidase inhibition attenuates endothelial dysfunction caused by chronic intermittent hypoxia in rats. | BACKGROUND: Xanthine oxidase is a major source of superoxide in the vascular endothelium. Previous work in humans demonstrated improved conduit artery function following xanthine oxidase inhibition in patients with obstructive sleep apnea.OBJECTIVES: To determine whether impairments in endothelium-dependent vasodilatio... | ['Acetylcholine', 'Allopurinol', 'Animals', 'Endothelium, Vascular', 'Free Radical Scavengers', 'Hypoxia', 'Male', 'Nitroprusside', 'Oxidative Stress', 'Rats', 'Rats, Sprague-Dawley', 'Vascular Resistance', 'Xanthine Oxidase'] | 21,846,958 | [['D02.092.211.111'], ['D03.633.100.759.160'], ['B01.050'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.217.500'], ['C23.888.852.079'], ['D01.248.497.158.291.350.550', 'D01.490.100.300.550', 'D01.625.400.100.325.550'], ['G03.673', 'G07.775.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Influence of Acceptance Goals on Relational Perceptions. | We examined whether relational perceptions (social involvement, relational value, interaction experience) differ depending on interaction acceptance goals (establish, maintain, or repair). Results indicated that relational perceptions were more positive in the maintain condition compared to the establish condition, whi... | ['Adult', 'Female', 'Goals', 'Humans', 'Interpersonal Relations', 'Male', 'Self Concept', 'Social Perception', 'Young Adult'] | 25,635,652 | [['M01.060.116'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.752.747.792'], ['F02.463.593.752'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antidepressant drug consumption and public health indicators in Italy, 1955 to 2000. | OBJECTIVE: This study investigated the impact of the increasing consumption of selective serotonin reuptake inhibitors (SSRIs) and newer anti-depressants on the following public health indicators: (1) suicide rates, (2) proportion of completed suicides by poisoning with solid or liquid substances, and (3) hospital admi... | ['Adult', 'Aged', 'Antidepressive Agents', 'Cause of Death', 'Depressive Disorder', 'Drug Industry', 'Drug Utilization', 'Female', 'Humans', 'Italy', 'Male', 'Mortality', 'Patient Admission', 'Poisoning', "Practice Patterns, Physicians'", 'Serotonin Uptake Inhibitors', 'Sex Distribution', 'Suicide'] | 15,960,569 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.427.700.122'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['F03.600.300'], ['J01.576.655.750'], ['N04.452.706.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E05.318.308... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social P... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Controlled clinical trials on the Pizhen and massage for the treatment of thoracic lateral cutaneous nerve entrapment syndrome]. | OBJECTIVE: To investigate the clinical effects of Pizhen for the treatment of thoracic lateral cutaneous nerve entrapment syndrome.METHODS: From March 2004 to April 2008, among the 320 patients with thoracic lateral cutaneous nerve entrapment syndrome, 160 patients (105 patients were male and 55 patients were female, r... | ['Acupuncture Therapy', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Massage', 'Middle Aged', 'Nerve Compression Syndromes', 'Treatment Outcome', 'Young Adult'] | 19,817,193 | [['E02.190.044'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.599.750.750', 'E02.779.867.880.750', 'E02.831.535.867.880.750'], ['M01.060.116.630'], ['C10.668.829.550'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['M01.060.116.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. | Experimental allergic encephalomyelitis (EAE) was generated in SJL and B10.PL mice by using the synthetic myelin basic protein peptides. Inflammation in brain and spinal cord preceded clinical signs of disease. Infiltrating lymphocytes were predominantly Lyt1+ (CD5+), L3T4+ (CD4+) T cells, until day 18. After that, F4/... | ['Animals', 'Antigens, Differentiation', 'Encephalomyelitis, Autoimmune, Experimental', 'Female', 'Histocompatibility Antigens Class II', 'Inflammation', 'Interferon-gamma', 'Interleukin-2', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred Strains', 'Monocytes', 'Myelin Basic Protein', 'Peptides', 'T-Lymphocyte Subsets',... | 1,370,583 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['C23.550.470'], ['D12.644.276.374.440.893', 'D12.644.276.374.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Discharge patterns of chicken cochlear ganglion neurons following kanamycin-induced hair cell loss and regeneration. | Hair cells in the basal, high frequency region (> 1100 Hz) of the chicken cochlea were destroyed with kanamycin (400 mg/kg/d x 10 d) and allowed to regenerate. Afterwards, single unit recordings were made from cochlear ganglion neurons at various times post-treatment. During the first few weeks post-treatment, only neu... | ['Animals', 'Auditory Threshold', 'Chickens', 'Cochlea', 'Electrophysiology', 'Ganglia, Sensory', 'Hair Cells, Vestibular', 'Kanamycin', 'Microscopy, Electron, Scanning', 'Nerve Regeneration', 'Neurons'] | 8,151,523 | [['B01.050'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A09.246.300.246'], ['H01.158.344.528', 'H01.158.782.236'], ['A08.340.390', 'A08.800.350'], ['A08.675.650.395', 'A08.675.650.915.750.600.675', 'A08.800.950.750.600.675', 'A09... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mucin-like protein, a saliva component involved in brown planthopper virulence and host adaptation. | The rice brown planthopper (BPH), Nilaparvata lugens, can rapidly adapt to new resistant rice varieties within several generations, rendering its management burdensome. However, the molecular mechanism underlying its adaptability remains unclear. In this study, we investigated the potential role of mucin-like protein (... | ['Animals', 'Antibiosis', 'Feeding Behavior', 'Hemiptera', 'Insect Proteins', 'Mucins', 'Oryza', 'RNA Interference', 'RNA, Double-Stranded', 'Saliva', 'Sequence Analysis, DNA'] | 28,115,117 | [['B01.050'], ['G06.550.050', 'G16.062'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.500.131.617.412'], ['D12.776.093.500'], ['D12.776.395.560.631'], ['B01.650.940.800.575.912.250.822.616'], ['G05.308.203.374.790'], ['D13.444.735.490', 'G02.111.570.820.486.775', 'G05.360.580.775'], ['A12.200.666']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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