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Safety and Tolerability of Ketamine Use in Treatment-Resistant Bipolar Depression Patients with Regard to Central Nervous System Symptomatology: Literature Review and Analysis. | The current psychopharmacological treatment approaches for major depression focus on monoaminergic interventions, which are ineffective in a large proportion of patients. Globally, treatment-resistant bipolar depression (TRBD) affects up to 33% of depressive patients receiving treatment. Certain needs are still unmet a... | ['Administration, Intravenous', 'Administration, Oral', 'Antidepressive Agents', 'Bipolar Disorder', 'Comorbidity', 'Depressive Disorder, Major', 'Depressive Disorder, Treatment-Resistant', 'Dissociative Disorders', 'Humans', 'Ketamine'] | 32,050,466 | [['E02.319.267.082'], ['E02.319.267.100'], ['D27.505.954.427.700.122'], ['F03.084.500'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.300.375'], ['F03.600.300.388'], ['F03.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.392.368.367.652']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Changes of cholinergic, noradrenergic and serotonergic synaptic transmission indices elicited by ethylcholine aziridinium ion (AF64A) infused intraventricularly. | Bilateral (3 nmol/side) i.c.v. infusion of ethylcholine aziridinium ion (AF64A) causes a 70% decrease of hippocampal acetylcholine content lasting for longer than 30 days without changing the density of hippocampal recognition sites for muscarinic ligands. In hippocampal slices prepared from rats receiving i.c.v. AF64A... | ['Acetylcholine', 'Animals', 'Aziridines', 'Azirines', 'Binding Sites', 'Choline', 'Colforsin', 'Cyclic AMP', 'Hippocampus', 'Hydroxyindoleacetic Acid', 'Injections, Intraventricular', 'Norepinephrine', 'Prazosin', 'Rats', 'Rats, Inbred Strains', 'Serotonin', 'Synaptic Transmission'] | 2,437,288 | [['D02.092.211.111'], ['B01.050'], ['D03.383.097.217'], ['D03.383.097'], ['G02.111.570.120'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A08.186.211... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A body-weight-based method to estimate inorganic arsenic body burden through tilapia consumption in Taiwan. | In the present study, a stage-classified exposure model is developed to better characterize long-term arsenic (As) accumulation of both genders of children, adolescents, and adults through tilapia consumption in Taiwan. Ingestion rate as well as elimination rate of As are treated dynamically and are used to parameteriz... | ['Adolescent', 'Adult', 'Animals', 'Arsenic', 'Body Burden', 'Body Weight', 'Child', 'Female', 'Food Contamination', 'Humans', 'Male', 'Middle Aged', 'Risk Assessment', 'Tilapia', 'Water Pollutants, Chemical'] | 18,297,225 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D01.268.513.249'], ['E05.799.638.231', 'N06.850.460.200'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Stesolid emergency treatment: cave social fear! | PURPOSE: To explore psychosocial effects of rectiole emergency treatment.METHODS: Children who had at some time been treated with Stesolid rectiole for seizure relief were questioned about feelings of shame in relation to this treatment and their expectation of bullying by peers who might be aware of it. In addition to... | ['Administration, Rectal', 'Adolescent', 'Adult', 'Anticonvulsants', 'Child', 'Child, Preschool', 'Consciousness', 'Data Interpretation, Statistical', 'Diazepam', 'Emergency Medical Services', 'Female', 'Humans', 'Male', 'Parents', 'Schools', 'Seizures', 'Sex Characteristics', 'Shame', 'Surveys and Questionnaires'] | 18,065,244 | [['E02.319.267.120.655.750'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.080'], ['M01.060.406'], ['M01.060.406.448'], ['F02.463.188.409', 'F02.830.233'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['D03.633.100.079.080.070.216'], ['N02.421.297']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
[Lithium found in the total brain and brain lipids after intracranial injection of lithium in mice. Relation to the observed behavior disorders]. | Behavioural disturbances after lithium injection only appear in mice with concentrations above 8 microequivalents per brain. Below this value, no fixation of lithium occurs in the brain. At higher concentrations, the amount of lithium found in the brain and associated with brain lipids increases gradually to reach a pl... | ['Animals', 'Behavior, Animal', 'Brain Chemistry', 'Dose-Response Relationship, Drug', 'Injections', 'Lipids', 'Lithium', 'Mice', 'Mice, Inbred C57BL'] | 2,493,315 | [['B01.050'], ['F01.145.113'], ['G02.111.150', 'G03.185'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.267.530'], ['D10'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lung cancer stage-shift following a symptom awareness campaign. | BACKGROUND: Lung cancer outcomes in the UK are worse than in many other developed nations. Symptom awareness campaigns aim to diagnose patients at an earlier stage to improve cancer outcomes.METHODS: An early diagnosis campaign for lung cancer commenced in Leeds, UK in 2011 comprising public and primary-care facing com... | ['Abdominal Neoplasms', 'Aged', 'Aged, 80 and over', 'Diagnostic Self Evaluation', 'Early Detection of Cancer', 'Female', 'General Practice', 'Health Education', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Primary Health Care', 'Radiography, Thoracic'... | 29,950,525 | [['C04.588.033'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.360', 'F01.752.747.792.220'], ['E01.390.500'], ['H02.403.340'], ['I02.233.332', 'N02.421.726.407'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Evolution of nutrient export under urban development in areas affected by shallow watertable. | Surface water quality in catchments undergoing urbanisation may be affected by the release of pre-existing (or legacy) solutes, such as nutrients, as well as new sources associated with urban land use. This paper examines both for a number of urbanisation scenarios and adopting the modelling capability developed for th... | ['Hydrology', 'Models, Theoretical', 'Urbanization', 'Water Quality', 'Western Australia'] | 23,220,139 | [['H01.158.273.248.875', 'H01.277.249.875', 'J01.293.622'], ['E05.599'], ['I01.880.853.400.726'], ['N06.850.460.350.080.750', 'N06.850.460.790.730'], ['Z01.639.100.996', 'Z01.678.100.373.996']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Flavonoid constituents from Spiranthes australis LINDL. | Chemical investigation of the whole plant of Spiranthes australis (R. BROWN) LINDL. resulted in the isolation and characterization of three new flavonoid constituents, 5-hydroxy-4'-[(2-isopentenyl)oxy]-3,7,3'-trimethoxyflavone (1), 3-O-[[O-beta-D-xylopyranosyl]-(1-->2)-beta-D-glucopyranosyl]-8-(p-hydroxy-benzyl)-kaempf... | ['Cell Line, Tumor', 'Chromatography, Thin Layer', 'Dimethyl Sulfoxide', 'Drug Screening Assays, Antitumor', 'Flavonoids', 'Humans', 'Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Orchidaceae', 'Solvents', 'Spectrometry, Mass, Electrospray Ionization', 'Tetrazolium Salts', 'Thiazoles'] | 18,981,613 | [['A11.251.210.190', 'A11.251.860.180'], ['E05.196.181.400.537'], ['D02.886.640.150'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['E05.196.867.519'], ['B01.650.940.80... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relation among aldosterone, galectin-3, and myocardial fibrosis: a prospective clinical pilot follow-up study. | UNLABELLED: Primary aldosteronism has been associated with myocardial fibrosis, and is the most common cause of secondary hypertension. We previously showed that aldosterone can induce the secretion of galectin-3. The aim of this study was to investigate the association between myocardial fibrosis and plasma galectin-3... | ['Adrenalectomy', 'Aldosterone', 'Electrocardiography', 'Female', 'Fibrosis', 'Follow-Up Studies', 'Galectin 3', 'Humans', 'Male', 'Middle Aged', 'Myocardium', 'Pilot Projects', 'Prospective Studies'] | 27,190,071 | [['E04.270.115'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C23.550.355'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D12.776.503.307.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The oculocephalic response in the evaluation of the dizzy patient. | The oculocephalic response (OCR) is a simple office maneuver that assesses the vestibulo-ocular reflex (VOR). An abnormal response is manifested clinically as refixation saccades following a rapid horizontal head movement. Because little attention has been given to the OCR in the literature, a prospective study was und... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Caloric Tests', 'Child', 'Dizziness', 'Female', 'Fixation, Ocular', 'Head', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Movement', 'Prospective Studies', 'Saccades', 'Sensitivity and Specificity'] | 8,544,630 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.382.900.150'], ['M01.060.406'], ['C23.888.592.763.237'], ['G14.350.253'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['E05.318.372.500.750.625', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stress-induced impairment of inhibitory avoidance learning in female neuromedin B receptor-deficient mice. | Neuromedin B (NMB) is a mammalian bombesin (BN)-like peptide that exerts its function via the neuromedin B receptor (NMB-R). The NMB/NMB-R system is involved in stress response, and therefore we examined behavioral properties in female mice lacking NMB-R using a restraint-induced stress paradigm. Thirty minutes of rest... | ['Animals', 'Avoidance Learning', 'Blood Glucose', 'Electroshock', 'Female', 'Genotype', 'Maze Learning', 'Metabolism, Inborn Errors', 'Mice', 'Motor Activity', 'Pain', 'Receptors, Bombesin', 'Restraint, Physical', 'Stress, Physiological'] | 12,576,129 | [['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['D09.947.875.359.448.500'], ['E05.723.402.403', 'F04.669.224'], ['G05.380'], ['F02.463.425.874.500'], ['C16.320.565', 'C18.452.648'], ['B01.050.150.900.649.313.992.635.505.500'], ['F01.145.632', 'G11.427.410.698'], ['C23.888.592.612', 'F02.830.816.444', 'G11.56... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential induction of apoptosis in Swiss 3T3 cells by nitric oxide and the nitrosonium cation. | We have investigated the effect of nitric oxide (NO) on apoptosis in Swiss 3T3 fibroblasts and compared it to the effect of the nitrosonium cation (NO+). Both species induced apoptosis, confirmed by electron microscopy, propidium iodide staining, DNA laddering and activation of caspases. The kinetics of triggering apop... | ['3T3 Cells', 'Acetylcysteine', 'Animals', 'Antidotes', 'Antioxidants', 'Apoptosis', 'Ascorbic Acid', 'Carrier Proteins', 'Cations', 'DNA Fragmentation', 'Dose-Response Relationship, Drug', 'Free Radical Scavengers', 'Glutathione', 'Hydrogen-Ion Concentration', 'Membrane Proteins', 'Mice', 'Microscopy, Electron', 'Micr... | 9,378,780 | [['A11.251.210.100', 'A11.329.228.100'], ['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['D27.505.696.706.037', 'D27.720.799.037'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D12.776.157'], ['D01.248.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload. | Xanthine oxidoreductase (XOR) is increased in the left ventricle (LV) of humans with volume overload (VO), and mitochondrial inhibition of the respiratory chain occurs in animal models of VO. Because mitochondria are both a source and a target of reactive oxygen and nitrogen species, we hypothesized that activation of ... | ['Allopurinol', 'Animals', 'Arteriovenous Fistula', 'Cardiac Volume', 'Disease Models, Animal', 'Enzyme Inhibitors', 'Heart Failure', 'Mitochondria', 'Myocytes, Cardiac', 'Rats', 'Rats, Sprague-Dawley', 'Xanthine Oxidase'] | 21,925,594 | [['D03.633.100.759.160'], ['B01.050'], ['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['G09.330.380.249'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.389'], ['C14.280.434'], ['A11.284.430.214.190.875.564', 'A11.28... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
No effect of dose, hepatic function, or nutritional status on 5-FU clearance following continuous (5-day), 5-FU infusion. | One hundred and eighty seven patients (155 males, 32 females) with histologically proven and previously untreated head and neck cancer were entered in the study. A total of 222 cycles of therapy were analyzed (cisplatin 100 mg m-2 on day 1 and 5-day continuous intravenous infusion of 5-FU 550-1069 mg m-2 day-1, mean 87... | ['Blood Proteins', 'Dose-Response Relationship, Drug', 'Female', 'Fluorouracil', 'Head and Neck Neoplasms', 'Humans', 'Infusions, Intravenous', 'Liver', 'Liver Function Tests', 'Male', 'Nutritional Status'] | 1,419,604 | [['D12.776.124'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.383.742.698.875.404'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['A03.620'], ['E01.370.372.460'], ['G07.203.650.650', 'N01.224.425.525']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Different effects of anthocyanins and phenolic acids from wild blueberry (Vaccinium angustifolium) on monocytes adhesion to endothelial cells in a TNF-á stimulated proinflammatory environment. | SCOPE: Monocyte adhesion to the vascular endothelium is a crucial step in the early stages of atherogenesis. This study aims to investigate the capacity of an anthocyanin (ACN) and phenolic acid (PA) rich fraction (RF) of a wild blueberry, single ACNs (cyanidin, malvidin, delphinidin) and related metabolites (protocate... | ['Anthocyanins', 'Atherosclerosis', 'Blueberry Plants', 'Cell Adhesion', 'E-Selectin', 'Endothelium, Vascular', 'Gallic Acid', 'Glucosides', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Hydroxybenzoates', 'Intercellular Adhesion Molecule-1', 'Monocytes', 'NF-kappa B', 'Tumor Necrosis Factor-alpha', 'Vascular Ce... | 27,324,255 | [['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['C14.907.137.126.307'], ['B01.650.940.800.575.912.250.341.937.774.249'], ['G04.022'], ['D12.776.395.550.200.700.300', 'D12.776.503.843.300', 'D12.776.543.550.200.700.300', 'D23.050.301.350.700.300'], ['A07.015.700.500', 'A10... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Platelet function in sickle cell disease during steady state. | Platelet function was investigated in 37 patients with sickle cell disease during steady state. The measurement of platelet aggregation in whole blood, demonstrating interaction of sickle cells and platelets, showed increased activity in patients compared to controls. In contrast, by classical platelet aggregation in p... | ['Adenosine Triphosphate', 'Adolescent', 'Adult', 'Anemia, Sickle Cell', 'Blood Platelets', 'Child', 'Child, Preschool', 'Fibrinopeptide A', 'Humans', 'Platelet Aggregation', 'Platelet Factor 4', 'Thrombin', 'beta-Thromboglobulin'] | 2,143,013 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['M01.060.057'], ['M01.060.116'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['A11.118.188', 'A15.145.229.188'], ['M01.060.406'], ['M01.060.406.448'], ['D12.644.200', 'D12.776.124.125.515', 'D12.77... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antibiogram and plasmid profiling of carbapenemase and extended spectrum Beta-lactamase (ESBL) producing Escherichia coli and Klebsiella pneumoniae in Abeokuta, South western, Nigeria. | BACKGROUND: The increased reports of ESBL dissemination from various centres in south western, Nigeria and the recent emergence of carbapenem resistant bacteria prompted the conception of this study.OBJECTIVES: To demonstrate the relationship between high molecular weight plasmids and the expression of antibiotic multi... | ['Adolescent', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Child', 'Child, Preschool', 'Escherichia coli', 'Escherichia coli Infections', 'Humans', 'Infant', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Microbial Sensitivity Tests', 'Middle Aged', 'Nigeria', 'Plasmids', 'Prevalence', 'Young Adult', 'beta-Lactamase... | 24,940,337 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['M01.060.406'], ['M01.060.406.448'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.150.252.400.310.503'], ['B03.440.450.425.425... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Computed tomographic analysis of temporal maxillary stability and pterygomaxillary generate formation following pediatric Le Fort III distraction advancement. | BACKGROUND: Le Fort III distraction requires generation of bone in the pterygomaxillary region. The authors performed retrospective digital analysis on temporal fine-cut computed tomographic images to quantify both radiographic evidence of pterygomaxillary region bone formation and relative maxillary stability.METHODS:... | ['Acrocephalosyndactylia', 'Adolescent', 'Child', 'Child, Preschool', 'Craniofacial Dysostosis', 'Humans', 'Maxilla', 'Maxillofacial Abnormalities', 'Osteogenesis', 'Osteogenesis, Distraction', 'Osteotomy, Le Fort', 'Tomography, X-Ray Computed'] | 21,042,122 | [['C05.116.099.370.894.232.015', 'C05.116.099.370.894.819.100', 'C05.660.207.240.100', 'C05.660.585.800.100', 'C05.660.906.364.100', 'C05.660.906.819.100', 'C16.131.621.207.240.100', 'C16.131.621.585.800.100', 'C16.131.621.906.364.100', 'C16.131.621.906.819.100'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pulmonary oxidative stress, inflammation, and dysregulated iron homeostasis in rat models of cardiovascular disease. | Underlying cardiovascular disease (CVD) is a risk factor for the exacerbation of air pollution health effects. Pulmonary oxidative stress, inflammation, and altered iron (Fe) homeostasis secondary to CVD may influence mammalian susceptibility to air pollutants. Rodent models of CVD are increasingly used to examine mech... | ['Animals', 'Ascorbic Acid', 'Biomarkers', 'Bronchoalveolar Lavage Fluid', 'Cardiovascular Diseases', 'Disease Models, Animal', 'Ferritins', 'Gene Expression', 'Glutathione', 'Heart Failure', 'Hemodynamics', 'Homeostasis', 'Hypertension', 'Inflammation', 'Iron', 'Lung', 'Lung Diseases', 'Male', 'Obesity', 'Oxidative St... | 20,391,109 | [['B01.050'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D23.101'], ['E05.927.100.500'], ['C14'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['G05.297'], ['D12.644.456.448'], ['C14.280.434'], ['G09.330.380'], ['G07.410'], ['C14.907.489'], ['C23.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamic models of infectious diseases as regulators of population sizes. | Five SIRS epidemiological models for populations of varying size are considered. The incidences of infection are given by mass action terms involving the number of infectives and either the number of susceptibles or the fraction of the population which is susceptible. When the population dynamics are immigration and de... | ['Animals', 'Communicable Diseases', 'Humans', 'Incidence', 'Mathematics', 'Models, Biological', 'Population Density'] | 1,522,392 | [['B01.050'], ['C01.221', 'C23.550.291.531'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['H01.548'], ['E05.599.395'], ['N01.224.600', 'N06.850.505.400.600']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Effects of eye tracking stimulation on movement of body's center of gravity and head in elderly subjects]. | This study was designed to investigate the effects of eye tracking stimulation on the movement of the body's center of gravity (CG) and the head in aged persons 60 years old and above. Twenty-three healthy aged subjects ranging from 60 to 79 years old and 10 healthy young subjects were asked to pursue a pendulously mov... | ['Adult', 'Age Factors', 'Aged', 'Female', 'Fixation, Ocular', 'Gravitation', 'Head', 'Humans', 'Male', 'Middle Aged', 'Movement', 'Photic Stimulation', 'Postural Balance'] | 1,560,301 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G14.350.253'], ['G01.060.350'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['E05.723.729'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Failure of a Mycobacterium tuberculosis DeltaRD1 DeltapanCD double deletion mutant in a neonatal calf aerosol M. bovis challenge model: comparisons to responses elicited by M. bovis bacille Calmette Guerin. | An attenuated Mycobacterium tuberculosis RD1 knockout and pantothenate auxotroph (mc(2)6030) vaccine administered at 2 weeks of age failed to protect calves from low dose, aerosol M. bovis challenge at 2.5 months of age. In contrast, M. bovis bacille Calmette Guerin (BCG)-vaccinates had reduced tuberculosis-associated ... | ['Aerosols', 'Animals', 'Animals, Newborn', 'Antigens, Bacterial', 'BCG Vaccine', 'Bacterial Proteins', 'Cattle', 'Cells, Cultured', 'Gene Deletion', 'Leukocytes', 'Mycobacterium bovis', 'Mycobacterium tuberculosis', 'Tuberculosis Vaccines', 'Vaccination'] | 17,931,755 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['B01.050.050.282'], ['D23.050.161'], ['D20.215.894.135.825.100'], ['D12.776.097'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['G05.365.590.762.320', 'G05.558.800.320'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['B03.510.024.962.500.402', 'B03.510.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Failure to demonstrate peri-infarct depolarizations by repetitive MR diffusion imaging in acute human stroke. | BACKGROUND AND PURPOSE: Peri-infarct depolarizations (PIDs) have been demonstrated with diffusion-weighted MRI (DWI) in experimental stroke and are regarded as an important mechanism of ischemic injury. We tested the hypothesis that PIDs are of relevance for the early enlargement of human brain infarcts.METHODS: Ten st... | ['Acute Disease', 'Brain', 'Cerebral Infarction', 'Cortical Spreading Depression', 'Echo-Planar Imaging', 'Humans', 'Stroke', 'Subtraction Technique'] | 11,108,746 | [['C23.550.291.125'], ['A08.186.211'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['G11.561.200.500.300'], ['E01.370.350.825.500.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Influence of salivary Ph on the correlation between salivary and plasma levels of phenobarbital in the neonatal period]. | The influence of salivary pH on the estimate of blood barbiturates obtained by measuring phenobarbital on saliva at newborn age. | ['Barbiturates', 'Humans', 'Hydrogen-Ion Concentration', 'Infant, Newborn', 'Phenobarbital', 'Regression Analysis', 'Saliva'] | 2,733,641 | [['D03.383.742.698.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.703.520'], ['D03.383.742.698.253.650'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['A12.200.666']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Spacer inhalation technique and deposition of extrafine aerosol in asthmatic children. | The aim of the present study was to measure airway, oropharyngeal and gastrointestinal deposition of (99m)Tc-labelled hydrofluoroalkane-beclomethasone dipropionate after inhalation via a pressurised metered-dose inhaler and spacer (Aerochamber Plus) in asthmatic children. A group of 24 children (aged 5-17 yrs) with mil... | ['Administration, Inhalation', 'Adolescent', 'Aerosols', 'Anti-Asthmatic Agents', 'Asthma', 'Beclomethasone', 'Child', 'Child, Preschool', 'Female', 'Gastrointestinal Tract', 'Humans', 'Lung', 'Male', 'Metered Dose Inhalers', 'Oropharynx', 'Radionuclide Imaging', 'Tissue Distribution'] | 17,005,581 | [['E02.319.267.050'], ['M01.060.057'], ['D20.280.055', 'D26.255.165.055'], ['D27.505.954.796.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D04.210.500.745.432.769.125', 'D04.210.500.883.154'], ['M01.060.406'], ['M01.060.406.448'], ['A03.556'], ['B01.050.150.900.649.313.988.400.112.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections. | INTRODUCTION: Measurement of prohormones representing different pathophysiological pathways could enhance risk stratification in patients with community-acquired pneumonia (CAP) and other lower respiratory tract infections (LRTI).METHODS: We assessed clinical parameters and five biomarkers, the precursor levels of adre... | ['Aged', 'Aged, 80 and over', 'Biomarkers', 'Cross Infection', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Models, Statistical', 'Pneumonia', 'Predictive Value of Tests', 'ROC Curve', 'Respiratory Tract Infections', 'Switzerland', 'Treatment Outcome'] | 20,529,344 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['C01.248', 'C23.550.291.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Free-feeding patterns of rats: effects of pyrogen and dietary protein content. | Infusion of bacterial pyrogen (Priomen) was accompanied by an increase in body temperature, an increase in heat production, and a decrease in the voluntary food intake ofrats fed high-as well as low-protein diets. The magnitude of this pyrogen-induced depression of food intake was comparable for both diets. However, in... | ['Animals', 'Body Temperature', 'Body Temperature Regulation', 'Chick Embryo', 'Depression, Chemical', 'Dietary Proteins', 'Eating', 'Male', 'Pyrogens', 'Rats', 'Time Factors'] | 1,130,528 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['A13.350.150', 'A16.331.200'], ['G07.690.773.750'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.283', 'G10.261.330'], ['D27.888.569.673'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.910.857... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Possible causative factors in epidemic incidence of plantar warts]. | A locally increased incidence of plantar warts in schoolchildren was demonstrated statistically, although the origins and causes of the epidemic remain unclear. Excessively sweating feet rather than barefoot gymnastics in school, and perhaps the wearing of rubber boots or nylon stockings appear to facilitate the infect... | ['Adolescent', 'Child', 'Epidemiologic Methods', 'Female', 'Foot', 'Humans', 'Male', 'Warts'] | 996,488 | [['M01.060.057'], ['M01.060.406'], ['E05.318', 'N06.850.520'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.256.650.810', 'C01.925.825.810', 'C01.925.928.914', 'C17.800.838.790.810']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isocitrate dehydrogenase 1 analysis differentiates gangliogliomas from infiltrative gliomas. | Recent work has identified novel point mutations in isocitrate dehydrogenase 1 (IDH1) in the majority of the World Health Organization grades II and III infiltrative gliomas and secondary grade IV glioblastomas. Gangliogliomas consist of neoplastic ganglion and glial cells and, in contrast to infiltrative gliomas, are ... | ['Adolescent', 'Adult', 'Aged', 'Analysis of Variance', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Cohort Studies', 'DNA Mutational Analysis', 'Female', 'Ganglioglioma', 'Glioma', 'Humans', 'Infant', 'Isocitrate Dehydrogenase', 'Male', 'Middle Aged', 'Mutation', 'Retrospective Studies', 'Risk Factors', 'Statistic... | 21,314,850 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.393.760.700... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Fossil platyrrhine forelimb bones from the early miocene of Argentina. | Primate scapula and ulna fragments of uncertain taxonomic affinity (MACN-SC 101) have been recovered from the Pinturas deposits at Arroyo Feo, Santa Cruz, Argentina in association with Santacrucian (Early Miocene) land mammals. Least-squares regression of body weight on surface area and on height of the glenoid fossa o... | ['Animals', 'Argentina', 'Cebidae', 'Fossils', 'Paleontology', 'Scapula', 'Ulna'] | 3,218,668 | [['B01.050'], ['Z01.107.757.077'], ['B01.050.150.900.649.313.988.400.600.150'], ['I01.076.368.584.311'], ['H01.277.875', 'I01.076.368.584'], ['A02.835.232.087.783'], ['A02.835.232.087.090.850']] | ['Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Changes induced by a fructose-rich diet on hepatic metabolism and the antioxidant system. | AIMS: The effect of a three-week fructose-rich diet (FRD) upon gene expression, protein and activity levels of liver antioxidant system and carbohydrate metabolism was studied.MAIN METHODS: Serum glucose (fasting and after a glucose load), triglyceride and insulin levels of normal male Wistar rats were measured. In liv... | ['Animals', 'Antioxidants', 'Blood Glucose', 'Body Weight', 'Carbohydrate Metabolism', 'Diet', 'Dietary Carbohydrates', 'Drinking Behavior', 'Fructose', 'Glucose Tolerance Test', 'Glutathione', 'Insulin', 'Lipid Peroxidation', 'Liver', 'Male', 'Protein Carbonylation', 'Rats', 'Rats, Wistar', 'Triglycerides'] | 20,470,786 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G02.111.158', 'G03.191'], ['G07.203.650.240'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Molecular morphology of the tetrodotoxin-binding sodium channel protein from Electrophorus electricus in solubilized and reconstituted preparations. | The appearance of detergent-solubilized voltage-regulated sodium channel protein was recently characterized by this laboratory. Negative-staining revealed rod-shaped particles measuring 40 X 170 A. Further studies have suggested that the actual configuration of this protein may be quite different from the rod-shaped st... | ['Animals', 'Carrier Proteins', 'Electric Organ', 'Electrophorus', 'Freeze Fracturing', 'Histocytochemistry', 'Ion Channels', 'Microscopy, Electron', 'Sodium', 'Sodium Channels', 'Solubility', 'Tetrodotoxin'] | 6,315,745 | [['B01.050'], ['D12.776.157'], ['A13.332'], ['B01.050.150.900.493.378.430.250'], ['E01.370.225.500.620.620.260', 'E01.370.225.750.600.620.260', 'E05.200.500.620.620.260', 'E05.200.750.600.620.260'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-biofilm and anti-inflammatory effect of a herbal nanoparticle mouthwash: a randomized crossover trial. | Laboratory evidence has demonstrated the antimicrobial effect of Melaleuca alternifolia (MEL) against oral microorganisms. This randomized, double-blind, crossover clinical trial, compared the anti-biofilm and anti-inflammatory effects of MEL nanoparticles with 0.12% chlorhexidine gluconate (CHX) on biofilm-free (BF) a... | ['Adolescent', 'Adult', 'Anti-Inflammatory Agents', 'Biofilms', 'Chlorhexidine', 'Cross-Over Studies', 'Dental Plaque', 'Dental Plaque Index', 'Double-Blind Method', 'Female', 'Gingival Crevicular Fluid', 'Humans', 'Male', 'Melaleuca', 'Mouthwashes', 'Nanoparticles', 'Oral Hygiene', 'Periodontal Diseases', 'Statistics,... | 31,859,706 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.158'], ['A20.593', 'G06.120'], ['D02.078.370.141.100'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Assuring the research competence of orthopedic graduates. | OBJECTIVES: To assure that orthopaedic residents have the knowledge needed to critically appraise the medical/surgical literature and the skills needed to design and conduct musculoskeletal and orthopaedic research.SETTING: Residency program of the Department of Orthopaedic Surgery, Sports Medicine and Rehabilitation a... | ['Adult', 'Biomedical Research', 'Curriculum', 'Humans', 'Internship and Residency', 'Mentors', 'Ohio', 'Orthopedics', 'Professional Competence', 'Research Support as Topic', 'Schools, Medical'] | 20,630,420 | [['M01.060.116'], ['H01.770.644.145'], ['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['M01.395'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.540', 'Z01.107.567.875.510.540'], ['H02.403.810.494'], ['I02.399.630'], ['N03.219.483.645'], ['I02.783.495.55... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
CMA conference to look at role research plays when critical policy decisions are being made. | Physician leaders will meet in Ottawa Feb. 28 and Mar. 1 for the CMA's 9th Annual Leadership Conference to examine how evidence, research and data influence health policy. For information or to register contact CMA Meetings and Travel Department, 800 663-7336, ext. 2274; fax 613 731-8047. | ['Breast Implants', 'Canada', 'Health Policy', 'Health Services Research', 'Humans', 'Leadership', 'Societies, Medical', 'United States', 'United States Food and Drug Administration'] | 9,033,431 | [['E07.695.140'], ['Z01.107.567.176'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['N03.540.828.589'], ['Z01.107.567.875'], ['I01.409.418.750.600.650.760', 'N03.540.348.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Effects of a nutrient-enriched water on water intake and indices of hydration in healthy domestic cats fed a dry kibble diet. | OBJECTIVE To evaluate the effects of drinking nutrient-enriched water (NW) on water intake and indices of hydration in healthy domestic cats fed a dry kibble diet ad libitum. ANIMALS 18 domestic shorthair cats. PROCEDURES Group-housed cats were assigned to tap water (TW; n = 9) or NW (9) groups. All cats received TW at... | ['Animal Feed', 'Animals', 'Cats', 'Diet', 'Drinking', 'Energy Intake', 'Female', 'Glomerular Filtration Rate', 'Glycerol', 'Male', 'Osmolar Concentration', 'Phosphates', 'Urinalysis', 'Water', 'Whey Proteins'] | 29,943,634 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G07.203.650.240'], ['G07.203.650.283.249', 'G10.261.330.249'], ['G07.203.650.240.340'], ['E01.370.390.400.300', 'G08.852.357'], ['D02.033.800.875.500', 'D09.853.875.500'], ['G02.640'], ['D01.029.260.700.675.374'... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Short-Term Efficacy and Correlates of Change in Health Weight Management Program for Chinese American Children. | A pretest and posttest study design was used to test a healthy weight management intervention with overweight and/or obese Chinese American children. Children attended 8-weekly small group sessions while parents attended a single 2-hour parent workshop. Children had their weight, height, blood pressure, waist and hip c... | ['Asian Americans', 'Body Mass Index', 'Body Weight', 'Child', 'Female', 'Health Status', 'Humans', 'Male', 'Parents', 'Pediatric Obesity', 'Program Evaluation', 'Quality of Life', 'Self Efficacy', 'Surveys and Questionnaires', 'Treatment Outcome', 'Weight Reduction Programs'] | 26,149,851 | [['M01.686.508.200.100', 'M01.686.754.225'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Baicalin inhibits breast cancer development via inhibiting I?B kinase activation in vitro and in vivo. | The aim of the present study was to investigate the effect and therapeutic potential of baicalin in breast cancer. Baicalin is used to treat inflammatory diseases. The effects of baicalin were assessed in breast cancer MCF-7 and MDA-MB‑231 cells, and human breast cancer xenograft mice. Cells were treated with 0, 20 or ... | ['Animals', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Drug Administration Schedule', 'Female', 'Flavonoids', 'Gene Expression Regulation, Neoplastic', 'Humans', 'I-kappa B Kinase', 'Injections, Intraperitoneal', 'MCF-7 Cells', 'Mice', 'Signal Transduction', 'Xenograft Model Antitum... | 30,320,365 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E02.319.283'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Foreign body in the middle ear, a hearing aid complication. | A 12-year-old boy with moderate to severe bilateral mixed hearing loss was planned for hearing aid placement. During the process of making ear mould impression, the impression material accidentally entered the right middle ear. Removal of the ear mould impression was possible permeatally under general anaesthesia. | ['Child', 'Ear, Middle', 'Foreign Bodies', 'Hearing Aids', 'Humans', 'Male'] | 19,248,709 | [['M01.060.406'], ['A09.246.397'], ['C26.392'], ['E07.305.906.500', 'E07.814.458'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blood eosinophilia, steroids, and rejection. | Blood eosinophilia is invariably associated with acute cellular episodes of rejection, characterized by blastogenic inflammation in fine-needle aspiration cytology of the renal transplant. The eosinophilic episode usually precedes the onset of inflammation by 1-4 days and carries no correlation with the intensity of th... | ['Clinical Trials as Topic', 'Cyclosporins', 'Eosinophilia', 'Graft Rejection', 'Humans', 'Immunosuppressive Agents', 'Inflammation', 'Random Allocation', 'Steroids'] | 3,901,441 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D04.345.566.235', 'D12.644.641.235'], ['C15.378.553.231'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C23.550.470'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibition of adhesion of Clostridium difficile to Caco-2 cells. | For many microorganisms, including Clostridium difficile, mucosal association is an important factor influencing intestinal colonisation and subsequent infection. Inhibition of adhesion of C. difficile to intestinal mucosa could be a new promising strategy for prevention and treatment of antibiotic-associated diarrhoea... | ['Animals', 'Bacterial Adhesion', 'Caco-2 Cells', 'Cattle', 'Clostridioides difficile', 'Colostrum', 'Enterocolitis, Pseudomembranous', 'Humans', 'Milk Proteins', 'Virulence', 'Whey Proteins', 'Xylitol'] | 8,856,319 | [['B01.050'], ['G06.099.050'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['B01.050.150.900.649.313.500.380.271'], ['B03.353.625.657.500'], ['A12.200.194'], ['C01.150.252.410.222.310', 'C06.405.205.596.800', 'C06.405.469.363.800'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.790.520', 'D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The postoperative course of gamma-glutamyl transpeptidase--a marker of cytomegalovirus (CMV) replication risk? | Cytomegalovirus (CMV) infection is a common complication in the postoperative course of liver transplantation. In order to start early prophylactic therapy, but to avoid unnecessary treatment, or expensive screening, a desirable goal in post-transplant monitoring is to find appropriate markers in standard laboratory di... | ['Biomarkers', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Humans', 'Immunohistochemistry', 'Liver Transplantation', 'Postoperative Complications', 'Virus Replication', 'gamma-Glutamyltransferase'] | 11,156,355 | [['D23.101'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of metallothioneins in peripheral nerve function and regeneration. | The physiological role of the metallothionein (MT) family of proteins during peripheral nerve injury and regeneration was examined in Mt1+ 2 and Mt3 knockout (KO) mice. To this end, the right sciatic nerve was crushed, and the regeneration distance was evaluated by the pinch test 2-7 days postlesion (dpl) and electroph... | ['Animals', 'Axons', 'Female', 'Metallothionein', 'Mice', 'Mice, Knockout', 'Nerve Regeneration', 'Nerve Tissue Proteins', 'Peripheral Nerves', 'Sciatic Nerve'] | 12,861,386 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D12.776.556.670'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['G11.561.585', 'G16.762.611'], ['D... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epidermal growth factor-like domain 7 predicts response to first-line chemotherapy and bevacizumab in patients with metastatic colorectal cancer. | The number of approved antiangiogenic drugs is constantly growing and emphasizes the need for predictive biomarkers. The aim of this study was to analyze the predictive value of epidermal growth factor-like domain 7 (EGFL7) and microRNA-126 (miR126) to first-line chemotherapy combined with bevacizumab, in patients with... | ['Adult', 'Aged', 'Angiogenesis Inhibitors', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Bevacizumab', 'Calcium-Binding Proteins', 'Cohort Studies', 'Colorectal Neoplasms', 'Disease-Free Survival', 'EGF Family of Proteins', 'Endothelial Growth Factors... | 25,140,000 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.776.124.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Your highness: vertical positions as perceptual symbols of power. | Metaphorically, power equals up. Drawing on embodied theories of cognition, the author argues that thinking about power involves mental simulation of space and can be interfered with by perception of vertical differences. Study 1 assessed image schemas for power and found a shared vertical difference metaphor. Studies ... | ['Adult', 'Analysis of Variance', 'Female', 'Germany', 'Humans', 'Inhibition, Psychological', 'Judgment', 'Male', 'Metaphor', 'Power, Psychological', 'Psychological Theory', 'Psychomotor Performance', 'Reaction Time', 'Social Perception', 'Symbolism'] | 16,060,739 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F02.463.785.626'], ['K01.400.899.500', 'K01.752.798.500'], ['F01.658.780'], ['F02.739'], ['F02.808', 'G11.427.70... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Improved plainfilm diagnosis of right aortic arch anomalies with high kilovoltage-selective filtration-magnification technique. | In the pediatric patient, the presence of a right aortic arch is an important roentgen observation. It may be associated with vascular rings and cyanotic heart disease and may complicate the repair of tracheoesophageal fistula. It may be missed on conventional low KVP radiographs but is easily detected on high kilovolt... | ['Airway Obstruction', 'Aorta, Thoracic', 'Esophageal Atresia', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Methods', 'Radiographic Magnification', 'Tetralogy of Fallot', 'Trachea', 'Tracheoesophageal Fistula'] | 714,526 | [['C08.618.846.185'], ['A07.015.114.056.372'], ['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.581'], ['E01.370.350.700.710'], ['C14.240.400.849', 'C14.280.400.849', 'C16.131.240.400.849'], ['A04.889'], ['C06.267.250.725... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Epidemiology and pathogenesis of ureaplasma urealyticum in spontaneous abortion and early preterm labor. | The role of U. urealyticum in spontaneous and recurrent spontaneous abortion was studied in 633 women. Cervical colonization with U. urealyticum was found in 42.6% of 310 normal pregnant women, in 41.6% of 84 patients who underwent induced abortion, in 41.5% of 41 normal fertile patients, in 53.3% of 122 patients with ... | ['Abortion, Spontaneous', 'Cervix Uteri', 'Female', 'Humans', 'Microbiological Techniques', 'Obstetric Labor, Premature', 'Placenta', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Ureaplasma'] | 3,321,869 | [['C13.703.039', 'G08.686.784.769.496.125'], ['A05.360.319.679.256'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875', 'E05.200.875'], ['C13.703.420.491'], ['A16.710'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['B03.440.860.580.553.900']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nursing from an ethanol-intoxicated dam induces short- and long-term disruptions in motor performance and enhances later self-administration of the drug. | RATIONALE: During interactions with an ethanol-intoxicated dam, preweanling rats encode ethanol-related chemosensory information. These experiences have been observed to enhance subsequent recognition of ethanol's chemosensory properties and to modulate learning about ethanol.OBJECTIVE: The present study tested the eff... | ['Alcoholic Intoxication', 'Animals', 'Ethanol', 'Female', 'Lactation', 'Male', 'Maternal Behavior', 'Psychomotor Performance', 'Rats', 'Rats, Wistar', 'Self Administration'] | 15,252,290 | [['C25.775.100.175', 'F03.900.100.300'], ['B01.050'], ['D02.033.375'], ['G08.686.523', 'G08.686.702.500'], ['F01.829.263.370.215'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['E02.319.890', 'E02.900.890']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Large congenital melanocytic nevi may reflect paradominant inheritance implying allelic loss. | Large congenital melanocytic nevi have so far always been considered to occur sporadically, and until now little has been written about a possible role of heredity as a cause of this disorder. We reviewed familial cases of large congenital melanocytic nevi as reported in the literature and found 14 case reports with a ... | ['Female', 'Genetic Predisposition to Disease', 'Humans', 'Inheritance Patterns', 'Loss of Heterozygosity', 'Male', 'Mosaicism', 'Nevus, Pigmented', 'Skin Neoplasms'] | 14,693,484 | [['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.420'], ['G05.365.590.029.530'], ['G05.365.590.175.595'], ['C04.557.665.560.615'], ['C04.588.805', 'C17.800.882']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg. | The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce ... | ['DNA, Recombinant', 'Hepatitis B Surface Antigens', 'Hepatitis B Vaccines', 'Lettuce', 'Plant Growth Regulators', 'Plants, Genetically Modified', 'Seedlings', 'Vaccines, Edible'] | 19,287,831 | [['D13.444.308.460'], ['D23.050.327.495.500.475'], ['D20.215.894.899.955.400'], ['B01.650.940.800.575.912.250.100.500'], ['D27.505.696.377.760'], ['B01.650.520', 'B05.620.600'], ['A18.550', 'B01.650.819'], ['D12.776.828.868.915', 'D20.215.894.860.915', 'D20.215.894.865.915', 'D23.050.865.915']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of antimicrotubular agents on the fine structure of the Golgi complex in embryonic chick osteoblasts. | Embryonic chick frontal bones were cultured in the presence of colchicine or vinblastine and subsequently examined by tranmission electron microscopy. In control cultures the osteoblasts showed a large Golgi complex consisting of dictyosomes arranged in a well-defined juxtanuclear area. Microtubules were particularly n... | ['Animals', 'Chick Embryo', 'Colchicine', 'Culture Techniques', 'Frontal Bone', 'Golgi Apparatus', 'Microtubules', 'Osteoblasts', 'Vinblastine'] | 569,017 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['D03.132.225'], ['E05.481.500'], ['A02.835.232.781.375'], ['A11.284.430.214.190.875.336'], ['A11.284.430.214.190.750.602'], ['A11.329.629'], ['D03.132.436.681.827.650', 'D03.633.100.473.402.681.827.650', 'D03.633.100.496.500.500.681.827.650']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Achieving stability and conformational specificity in designed proteins via binary patterning. | We have developed a method to determine the optimal binary pattern (arrangement of hydrophobic and polar amino acids) of a target protein fold prior to amino acid sequence selection in protein design studies. A solvent accessible surface is generated for a target fold using its backbone coordinates and "generic" side-c... | ['Animals', 'Calorimetry, Differential Scanning', 'Circular Dichroism', 'Databases as Topic', 'Guanidine', 'Homeodomain Proteins', 'Light', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Mutation', 'Protein Conformation', 'Protein Denaturation', 'Protein Engineering', 'Protein Folding', 'Recombinant Proteins'... | 11,152,617 | [['B01.050'], ['E05.196.131.310', 'E05.196.370.310'], ['E05.196.867.151'], ['L01.313.500.750.300.188', 'L01.470.750'], ['D02.078.370.472'], ['D12.776.260.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.867.519'], ['E05.599.595'], ['G05.365.590'], ['G02.111.570.820.709'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein. | A compendium of different types of abiotic chemical syntheses identifies a consensus set of 10 "prebiotic" á-amino acids. Before the emergence of biosynthetic pathways, this set is the most plausible resource for protein formation (i.e., proteogenesis) within the overall process of abiogenesis. An essential unsolved qu... | ['Amino Acids', 'Biophysical Phenomena', 'Calorimetry, Differential Scanning', 'Crystallography, X-Ray', 'Evolution, Molecular', 'Models, Molecular', 'Mutagenesis', 'Origin of Life', 'Protein Folding', 'Protein Stability', 'Proteins', 'Static Electricity'] | 23,341,608 | [['D12.125'], ['G01.154'], ['E05.196.131.310', 'E05.196.370.310'], ['E05.196.309.742.225'], ['G05.045.250', 'G16.075.250'], ['E05.599.595'], ['G05.558'], ['G16.650', 'I01.076.368.584.542'], ['G01.154.651', 'G02.111.688'], ['G02.111.700'], ['D12.776'], ['G01.358.500.249.820']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Lifetime growth and blood pressure in adolescence: Hong Kong's "Children of 1997" birth cohort. | OBJECTIVES: Blood pressure tracks from adolescence to adulthood and is positively associated with low birth weight and faster infant growth. Most observations are from Western populations; it is unclear whether these are biologically based or contextually specific. We examined the associations of growth with blood pres... | ['Adolescent', 'Birth Weight', 'Blood Pressure', 'Child', 'Child Development', 'Child, Preschool', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Hong Kong', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Prospective Studies'] | 23,230,068 | [['M01.060.057'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.600.875.249', 'G09.330.380.076'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.75... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice. | AIMS: To evaluate the effects of the beta-3 adrenoceptor agonist, mirabegron in a mouse model of detrusor overactivity induced by obesity.METHODS: C57BL/6 male mice were fed with standard chow or high-fat diet for 12 weeks. Lean and obese mice were treated orally with mirabegron (10 mg/kg/day) from the last 2 weeks of ... | ['Acetanilides', 'Adrenergic beta-3 Receptor Agonists', 'Animals', 'Body Weight', 'Carbachol', 'Cyclic AMP', 'Cyclic Nucleotide Phosphodiesterases, Type 4', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Obese', 'Muscle Contraction', 'Muscle, Smooth', 'Obesity', 'Thiazoles', 'Urinary Bladder', 'Urinary Bladder, Overactiv... | 27,794,199 | [['D02.065.199.092', 'D02.092.146.113.092'], ['D27.505.519.625.050.100.200.300', 'D27.505.696.577.050.100.200.300'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['D03.633.100.759.646... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of nicardipine prolonged-release implants after clipping for preventing cerebral vasospasm: from laboratory to clinical trial. | We have developed a drug delivery system using a vasodilating drug that can be implanted intracranially at the time of surgery for aneurysm clipping, without systemic side effects or side effects associated with long-term intrathecal drug administration. We started our project on 1994 for making a slowly releasing drug... | ['Animals', 'Disease Models, Animal', 'Dogs', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Drug Delivery Systems', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Nicardipine', 'Retrospective Studies', 'Subarachnoid Hemorrhage', 'Time Factors', 'Treatment Outcome', 'Vasodilator Agents', 'Vasospasm, Int... | 22,890,641 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Racial and ethnic differences in secular trends for childhood BMI, weight, and height. | OBJECTIVES: The prevalence of childhood overweight in the United States has markedly increased over the last 30 years. We examined differences in the secular trends for BMI, weight, and height among white, black, and Mexican-American children.RESEARCH METHODS AND PROCEDURES: Analyses were based on nationally representa... | ['Adolescent', 'African Americans', 'Age Factors', 'Body Height', 'Body Mass Index', 'Body Weight', 'Child', 'Child Nutrition Disorders', 'Child, Preschool', 'Chronic Disease', 'Ethnic Groups', 'European Continental Ancestry Group', 'Female', 'Hispanic Americans', 'Humans', 'Male', 'Mexican Americans', 'Nutrition Surve... | 16,571,857 | [['M01.060.057'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.3... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
From 'ecopathology' to 'agroecosystem health'. | The 'epidemiologic revolution' of the 1960s arose in response to the inability of reductionist methods to provide practical solutions to the complex problems of health and production in livestock systems. In a farm, there are not only interactions between animal factors and herd husbandry factors such as feeding, housi... | ['Animal Diseases', 'Animal Husbandry', 'Animals', 'Animals, Domestic', 'Ecosystem', 'France', 'Humans', 'Models, Organizational'] | 10,223,315 | [['C22'], ['J01.040.090'], ['B01.050'], ['B01.050.050.116'], ['G16.500.275.157', 'N06.230.124'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.670', 'N04.452.534']] | ['Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Use of the Sleep Apnea Scale of the Sleep Disorders Questionnaire (SA-SDQ) in adults with epilepsy. | OBJECTIVE: A growing body of literature supports the importance of sleep comorbidities in epilepsy. The prevalence of obstructive sleep apnea (OSA) in adults with epilepsy exceeds that of the general population, and its presence adversely impacts seizure control in some cases. The Sleep Apnea Scale of the Sleep Disorde... | ['Adult', 'Electroencephalography', 'Epilepsy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polysomnography', 'ROC Curve', 'Reproducibility of Results', 'Sleep Apnea, Obstructive', 'Surveys and Questionnaires', 'Video Recording'] | 24,397,915 | [['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520.625'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The effects of underrecorded forced expirations on spirometric lung function indexes. | A problem with short recorded lengths of expiration, encountered in a large heart attack intervention trial, illustrates the importance of standardization and training in spirometric lung function testing. At baseline, half of the trial's clinical centers had mean FVC values that were between 500 and 1,100 ml below tho... | ['Adult', 'Forced Expiratory Volume', 'Humans', 'Male', 'Middle Aged', 'Spirometry', 'Vital Capacity'] | 7,125,372 | [['M01.060.116'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.386.700.750'], ['E01.370.386.700.485.750.900', 'G09.772.850.970']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Learner-centred teaching in a non-learner-centred world: An interpretive phenomenological study of the lived experience of clinical nursing faculty. | BACKGROUND: With the growing complexities in the contemporary health care system, there is a challenge of preparing nurses for the practice demands. To this end, learner-centred teaching has emerged in many nursing curricula in Canada and evidence indicates its effectiveness in developing the essential practice skills ... | ['Adult', 'Canada', 'Clinical Competence', 'Curriculum', 'Faculty, Nursing', 'Female', 'Humans', 'Interviews as Topic', 'Middle Aged', 'Problem-Based Learning', 'Students, Nursing', 'Surveys and Questionnaires', 'Teaching'] | 29,857,305 | [['M01.060.116'], ['Z01.107.567.176'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Scale insects and mealy bugs (Homoptera: Coccoidea) attacking deciduous fruit trees in the western north coast of Alexandria, Egypt. | This investigation covered a survey of scale insects and mealy bugs infesting ten growing species of deciduous fruit trees in three localities in Alexandria govemorate. These localities were Merghem, Burg El-Arab, and El-Nahda about 50 Km. West of Alexandria under both rain-fed and irrigation system conditions. The com... | ['Animals', 'Climate', 'Ecosystem', 'Egypt', 'Ficus', 'Fruit', 'Geography', 'Hemiptera', 'Malus', 'Olea', 'Trees'] | 19,226,793 | [['B01.050'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.275.157', 'N06.230.124'], ['Z01.058.266.317'], ['B01.650.940.800.575.912.250.859.937.406.500'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['H01.277.500'], ['B01.050.500.131.617.412'], ['B01.650.940.800.575.912.250.859.937.500.444'], ['B01.650.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Multiple host-switching of Haemosporidia parasites in bats. | BACKGROUND: There have been reported cases of host-switching in avian and lizard species of Plasmodium (Apicomplexa, Haemosporidia), as well as in those infecting different primate species. However, no evidence has previously been found for host-swapping between wild birds and mammals.METHODS: This paper presents the r... | ['Animals', 'Birds', 'Chiroptera', 'Cytochrome b Group', 'Haemosporida', 'Host-Parasite Interactions', 'Phylogeny'] | 18,045,505 | [['B01.050'], ['B01.050.150.900.248'], ['B01.050.150.900.649.313.937'], ['D08.244.187', 'D12.776.422.220.187'], ['B01.043.075.380'], ['G16.527.200.400'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Lichen planus pemphigoides--report of a case and binding sites of circulating anti-basement membrane zone antibodies]. | In this paper, we initially report a case which had clinical, histological and immuno-histochemical features consistent with the diagnosis of lichen planus pemphigoides (LPP). We then examined in vitro binding sites of circulating anti-basement membrane zone (BMZ) antibodies (Ab) from the patient using skin substrate s... | ['Autoantibodies', 'Basement Membrane', 'Binding Sites, Antibody', 'Cell Membrane', 'Desmosomes', 'Female', 'Humans', 'Lichen Planus', 'Middle Aged', 'Pemphigoid, Bullous', 'Skin Diseases, Vesiculobullous'] | 2,691,740 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A10.272.220', 'A10.615.179'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['A11.284.149'], ['A11.284.149.165.420.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.859.475.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rural general practice training: experience of a rural general practice team and a postgraduate year two registrar. | INTRODUCTION: Undertaking training in rural areas is a recognised way of helping recruit staff to work in rural communities. Postgraduate year two medical doctors in New Zealand have been able to undertake a three-month placement in rural practice as part of their pre-vocational training experience since November 2010.... | ['Attitude of Health Personnel', 'Career Choice', 'Clinical Competence', 'General Practice', 'Humans', 'Internship and Residency', 'Personnel Selection', 'Program Evaluation', 'Rural Health Services', 'Students, Medical', 'Workforce'] | 23,998,175 | [['F01.100.050', 'N05.300.100'], ['F02.463.785.373.346.400'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['H02.403.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['N04.452.677.500'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N02.421.816'], ['M0... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Intrahepatic cholestasis of pregnancy: a retrospective case-control study of perinatal outcome. | OBJECTIVES: Intrahepatic cholestasis of pregnancy has been related to a high frequency of abnormal intrapartum fetal heart rate, amniotic fluid meconium, prematurity, and perinatal mortality. To determine whether these adverse perinatal outcomes could be improved with active intervention, we evaluated our results.STUDY... | ['Adult', 'Cesarean Section', 'Cholestasis, Intrahepatic', 'Female', 'Fetal Death', 'Fetal Membranes, Premature Rupture', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Obstetric Labor, Premature', 'Pre-Eclampsia', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Retrospective Studies'] | 8,141,222 | [['M01.060.116'], ['E04.520.252.500'], ['C06.130.120.135.250', 'C06.552.150'], ['C13.703.223', 'C23.550.260.585'], ['C13.703.420.339'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relationship between impaired adipogenesis of retroperitoneal adipose tissue and hypertrophic obesity: role of endogenous glucocorticoid excess. | Although the pro-adipogenic effect of glucocorticoid (GC) on adipose tissue (AT) precursor cell differentiation is openly accepted, the effect of chronically high peripheral levels of GC on AT mass expansion is not fully understood. In the present study, we aim to assess the in vitro adipogenic capacity of AT precursor... | ['Adipocytes', 'Adipogenesis', 'Adipose Tissue', 'Animals', 'Cell Differentiation', 'Cell Proliferation', 'Glucocorticoids', 'Humans', 'Inflammation', 'Intra-Abdominal Fat', 'Male', 'Obesity', 'Rats', 'Rats, Sprague-Dawley', 'Stromal Cells'] | 24,913,911 | [['A11.329.114'], ['G04.152.149'], ['A10.165.114'], ['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['A10.165.114.830.500.500'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Allograft prosthetic composite replacement for bone tumors. | Limb salvage for bone tumors has become the standard method of treatment. This technique involves removal of large segments of bone, most commonly around the hip and knee. Various types of reconstructive options are currently available, including osteoarticular allograft arthroplasty, modular oncology prosthetic arthro... | ['Adolescent', 'Adult', 'Aged', 'Arthroplasty', 'Bone Neoplasms', 'Bone Transplantation', 'Child', 'Extremities', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteosarcoma', 'Postoperative Complications', 'Prosthesis Design', 'Reoperation', 'Tendons', 'Transplantation, Homologous'] | 9,025,178 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110', 'E04.680.101'], ['C04.588.149', 'C05.116.231'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['M01.060.406'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.450.565.575.650', 'C04.557.450.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation of soluble and insoluble PrP oligomers in the normal human brain. | The central event in the pathogenesis of prion diseases involves a conversion of the host-encoded cellular prion protein PrP(C) into its pathogenic isoform PrP(Sc 1). PrP(C) is detergent-soluble and sensitive to proteinase K (PK)-digestion, whereas PrP(Sc) forms detergent-insoluble aggregates and is partially resistant... | ['Blotting, Western', 'Brain', 'Brain Chemistry', 'Centrifugation', 'Chromatography, Gel', 'Humans', 'PrPC Proteins'] | 23,070,047 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['E05.181'], ['E05.196.181.400.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.785.340.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Racial disparity in hypertension control: tallying the death toll. | PURPOSE: Black Americans with hypertension have poorer blood pressure control than their white counterparts, but the impact of this disparity on mortality among black adults is not known. We assessed differences in systolic blood pressure (SBP) control among white and black adults with a diagnosis of hypertension, and ... | ['Adult', 'African Americans', 'Aged', 'Comorbidity', 'European Continental Ancestry Group', 'Female', 'Health Status Disparities', 'Heart Diseases', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Risk Assessment', 'Stroke', 'United States'] | 19,001,301 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['M01.686.508.400'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E05.318... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Relationship between the tumor necrosis factor system and the serum interleukin-4, interleukin-5, interleukin-8, eosinophil cationic protein, and immunoglobulin E levels in the bronchial hyperreactivity of adults and their children. | The aim of the study was to investigate the activation of inflammatory mediators interleukin (IL)-4, IL-5, and IL-8; immunoglobulin E (IgE); and eosinophil cationic protein (ECP) and to evaluate the regulatory role of the tumor necrosis system (TNF) system in bronchial hyperreactivity. Adults who had suffered from bron... | ['Adolescent', 'Adult', 'Biomarkers', 'Blood Proteins', 'Child', 'Eosinophil Granule Proteins', 'Female', 'Forced Expiratory Volume', 'Humans', 'Hungary', 'Immunoglobulin E', 'Inflammation Mediators', 'Interleukin-4', 'Interleukin-5', 'Interleukin-8', 'Male', 'Parent-Child Relations', 'Ribonucleases', 'Spirometry', 'Tu... | 12,776,444 | [['M01.060.057'], ['M01.060.116'], ['D23.101'], ['D12.776.124'], ['M01.060.406'], ['D12.776.124.486.379'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The contribution of color to global motion processing. | This study investigates the contribution of color vision to global motion. We present evidence demonstrating that performance on a global motion task attains similar levels for both types of chromatic (L/M-cone opponent and S-cone opponent) and luminance stimuli at suprathreshold contrasts. We show, however, that the m... | ['Artifacts', 'Color Perception', 'Discrimination, Psychological', 'Humans', 'Motion Perception', 'Perceptual Masking', 'Photic Stimulation', 'Psychophysics', 'Sensory Thresholds'] | 18,842,081 | [['E05.047'], ['F02.463.593.932.217'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932.567'], ['F02.463.593.071.594', 'F02.463.593.932.733', 'G07.888.125.594'], ['E05.723.729'], ['E01.370.685', 'F04.096.753'], ['F02.463.593.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes. | The rat pancreatic AR42J-B13 (B-13) cell line differentiates into non-replicative hepatocyte-like (B-13/H) cells in response to glucocorticoid. Since this response is dependent on an induction of serine/threonine protein kinase 1 (SGK1), this may suggest that a general pivotal role for SGK1 in hepatocyte maturation. To... | ['Animals', 'Cell Differentiation', 'Cell Line', 'Endoderm', 'HEK293 Cells', 'Hepatocytes', 'Humans', 'Induced Pluripotent Stem Cells', 'L-Serine Dehydratase', 'Rats'] | 31,242,206 | [['B01.050'], ['G04.152'], ['A11.251.210'], ['A16.504.407'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['D08.811.520.232.400.600'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection. | Polymorphonuclear neutrophils (PMN) are key components of the inflammatory response contributing to the development of pathogen-specific immune responses. Following infection with Leishmania major, neutrophils are recruited within hours to the site of parasite inoculation. C57BL/6 mice are resistant to infection, and B... | ['Animals', 'Cells, Cultured', 'Disease Susceptibility', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Immunity, Innate', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-12 Subunit p40', 'Leishmania major', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Neutrophils', 'Nitrites', 'Phenotype', 'RNA, Messenger... | 17,449,725 | [['B01.050'], ['A11.251'], ['C23.550.291.687', 'G07.100.250'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['G12.450.564'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.5... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid analysis of 226Ra in waters by gamma-ray spectrometry. | Techniques for the determination of 226Ra in waters by gamma-ray spectrometry are examined, with an emphasis on methods capable of completion within 1-3 days of sample collection. Methods discussed utilise either: (i) the 186 keV 226Ra gamma ray, with the contribution from 235U being subtracted after a separate uranium... | ['Chemical Precipitation', 'Mining', 'Radon', 'Spectrometry, Gamma', 'Time Factors', 'Uranium', 'Water Pollutants, Radioactive'] | 9,204,522 | [['E05.196.150', 'G02.159'], ['J01.576.655.875.500'], ['D01.268.271.800', 'D01.268.613.700', 'D01.362.641.745', 'D01.496.749.305.800'], ['E05.196.867.776', 'E05.799.801'], ['G01.910.857'], ['D01.268.271.100.950', 'D01.268.556.900', 'D01.496.749.305.100.950', 'D01.552.020.940', 'D01.552.544.900'], ['D20.693.903', 'D27.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Curcumin and Cinnamaldehyde as PTP1B Inhibitors With Antidiabetic and Anticancer Potential. | BACKGROUND/AIM: Protein tyrosine phosphatase (PTP1B) is a potential target for the treatment of type 2 diabetes and cancer. Curcumin and cinnamaldehyde have been previously reported to have antidiabetic and anticancer potentials. The aim of this study was to investigate the effect of curcumin in comparison to cinnamald... | ['Acrolein', 'Antineoplastic Agents', 'Breast Neoplasms', 'Cell Survival', 'Curcumin', 'Diabetes Mellitus, Type 2', 'Drug Screening Assays, Antitumor', 'Female', 'Humans', 'Hypoglycemic Agents', 'MCF-7 Cells', 'Protein Tyrosine Phosphatase, Non-Receptor Type 1'] | 30,711,953 | [['D02.047.122'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['G04.346'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['C18.452.394.750.149', 'C19.246.300'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synergistic potential of Juniperus communis and Helichrysum italicum essential oils against nontuberculous mycobacteria. | OBJECTIVE: The present study evaluated the possible synergistic antimycobacterial interactions of Juniperus communis and Helichrysum italicum essential oils (EO).METHODS: Antimycobacterial potential was tested against Mycobacterium avium and Mycobacterium intracellulare using broth and water dilution method and checker... | ['Anti-Bacterial Agents', 'Biofilms', 'Drug Synergism', 'HeLa Cells', 'Helichrysum', 'Humans', 'Juniperus', 'Microbial Sensitivity Tests', 'Nontuberculous Mycobacteria', 'Oils, Volatile', 'Plant Oils'] | 30,916,640 | [['D27.505.954.122.085'], ['A20.593', 'G06.120'], ['G07.690.773.968.477'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.650.940.800.575.912.250.100.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.650.940.800.575.912.625.750.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thyroxine-binding prealbumin--an index of disease activity or nutritional status in rheumatoid arthritis? | Thyroxine-binding prealbumin (TBPA) concentrations were measured in 54 patients with rheumatoid arthritis (RA) and 50 control subjects. TBPA levels were significantly depressed in the RA patients, of whom 15 had values below the laboratory reference range. Although significant negative correlations were seen between TB... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Blood Sedimentation', 'C-Reactive Protein', 'Chymotrypsin', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nutrition Disorders', 'Prealbumin', 'Thyroxine-Binding Proteins', 'alpha 1-Antichymotrypsin'] | 6,430,378 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E01.370.225.625.125', 'E05.200.625.125'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. | Leukocyte infiltration in the CNS after trauma or inflammation is triggered in part by upregulation of the chemokine, monocyte chemoattractant protein-1 (MCP-1), in astrocytes. However the signals that induce the upregulation of MCP-1 in astrocytes are unknown. We have investigated the roles for ATP P2X7 receptor activ... | ['Adenosine Triphosphate', 'Animals', 'Astrocytes', 'Cells, Cultured', 'Cerebral Decortication', 'Chemokine CCL2', 'Dose-Response Relationship, Drug', 'Glial Fibrillary Acidic Protein', 'Hippocampus', 'Immunohistochemistry', 'Male', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Mitogen-Ac... | 11,549,724 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['E04.525.160'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['G07.69... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Autogenous dermal grafts for repair of temporomandibular joint disc perforations. | In five Macaca fascicularis monkeys bilateral 5-mm perforations of the intra-articular disc were followed by unilateral repair with autogenous dermal grafts. The monkeys were killed at three, six, 12, 24, and 36 weeks after surgery. The temporomandibular joints (TMJs) were removed en bloc, decalcified, and sectioned in... | ['Animals', 'Cartilage, Articular', 'Connective Tissue', 'Macaca fascicularis', 'Mandibular Condyle', 'Skin Transplantation', 'Temporal Bone', 'Temporomandibular Joint Disorders', 'Wound Healing'] | 3,531,442 | [['B01.050'], ['A02.165.407.150', 'A02.835.583.192'], ['A10.165'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['A02.835.232.781.324.502.632.600', 'A14.521.632.600'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['A02.835.232.781.885'], ['C05.500.607.221.897', 'C05.550.905', 'C05.651.243.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Four isoforms of the signal-transduction and RNA-binding protein QKI expressed during chicken spermatogenesis. | Genes expressed during spermatogenesis undergo alternative initiation and alternative splicing and may be under the control of a coordinated mechanism of RNA processing. A family of proteins that combine features of signal-transduction and RNA-binding molecules could be instrumental in this process. We have characteriz... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Binding Sites', 'Chickens', 'Conserved Sequence', 'DNA, Complementary', 'Gene Expression', 'Humans', 'Isomerism', 'Male', 'Mice', 'Mice, Quaking', 'Molecular Sequence Data', 'RNA', 'RNA, Messenger', 'RNA-Binding Proteins', 'Sequence Homology, Amino Acid', 'Signal Tra... | 9,547,512 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G02.111.570.580'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.297'], ['B01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Effect of central and peripheral serotonin-reactive structures on the cardiovascular system and respiration]. | In chronic experiments on dogs, the heterogenic effect of serotoninergic structures of the upper and lower parts of the limbic cortex's anterior area was revealed in respect to the heart rate and respiration. Administration of 0.2 mg of serotonin-adipinate (through chemotrodes, bilaterally, in 0.02 ml of saline) into t... | ['5-Hydroxytryptophan', 'Adipates', 'Animals', 'Cardiovascular Physiological Phenomena', 'Cardiovascular System', 'Dogs', 'Heart Rate', 'Limbic System', 'Receptors, Serotonin', 'Respiration', 'Serotonin'] | 6,607,182 | [['D12.125.072.050.850.479'], ['D02.241.081.337.052'], ['B01.050'], ['G09.330'], ['A07'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.600.875.500', 'G09.330.380.500'], ['A08.186.211.180'], ['D12.776.543.750.670.800', 'D12.776.543.750.695.800', 'D12.776.543.750.720.850'], ['G09.772.705'], ['D02.092.211.215.80... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. | Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by the glutamate transporter GLT1 (also known as EAAT2; refs 1, 2), the physiologically dominant astroglial protein. In spite of its critical importance in normal and abnormal synaptic activity, n... | ['Animals', 'Anti-Bacterial Agents', 'Ceftriaxone', 'Cell Count', 'Cells, Cultured', 'Central Nervous System', 'Drug Evaluation, Preclinical', 'Excitatory Amino Acid Transporter 2', 'Gene Expression Regulation', 'Genes, Reporter', 'In Vitro Techniques', 'Ischemic Preconditioning', 'Mice', 'Mice, Transgenic', 'Motor Neu... | 15,635,412 | [['B01.050'], ['D27.505.954.122.085'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.251'], ['A08.186'], ['E05.290.750', 'E05.337.550'], ['D12.776.157.530.200.249.500.500.750', 'D12.776.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Sagittal contour restoration and canal clearance in burst fractures of the thoracolumbar junction (T12-L1): the efficacy of timing of the surgery. | The efficacy of timing of surgery (short segment fixation using transpedicular screws), in burst fractures of thoracolumbar spine was evaluated between May 1993 and October 1994. The patients were divided into two groups according to time elapsed between injury and operation. Cases operated on within the first 24 h wer... | ['Adult', 'Female', 'Humans', 'Kyphosis', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Retrospective Studies', 'Spinal Fractures', 'Spinal Fusion', 'Thoracic Vertebrae', 'Time Factors'] | 8,592,262 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.800.500'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Assessment of the proliferative activity of tumor cells based on long-term phase-contrast microscopy CELL-IQ]. | This work presents results of long-term phase-contrast microscopy research of proliferative potential of tumor cell lines utilizing live-cell imaging technology Cell-IQ (Chip-Man Technologies Ltd, Finland). It was found that the machine vision technology allowed to obtain sufficient body of evidence about high-quality ... | ['Breast Neoplasms', 'Cell Line, Tumor', 'Cell Proliferation', 'Female', 'Humans', 'Kidney Neoplasms', 'Leiomyosarcoma', 'Male', 'Melanoma', 'Microscopy, Phase-Contrast', 'Neoplasms', 'Reproducibility of Results', 'Skin Neoplasms', 'Time Factors'] | 25,816,663 | [['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.557.450.590.455', 'C04.557.450.795.455'... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Possible contribution of cytomegalovirus infection to the high risk of (recurrent) venous thrombosis after renal transplantation. | Renal transplant recipients are at an increased risk of venous thrombosis, which has been regarded as a postoperative complication, although it may persist afterwards. As numerous case reports have shown that active cytomegalovirus (CMV) infection can be found at time of onset of venous thrombosis, and is frequently fo... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cytomegalovirus Infections', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Recurrence', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Time Factors', 'Venous Thrombosis'] | 18,217,144 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.925.256.466.245'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.52... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ghrelin and NUCB2/nesfatin-1 are expressed in the same gastric cell and differentially correlated with body mass index in obese subjects. | The orexigenic peptide ghrelin and the anorexigenic peptide nesfatin-1 are expressed by the same endocrine cell of the rat stomach, the X/A-like cell. However, data in humans are lacking, especially under conditions of obesity. We collected gastric tissue of obese patients undergoing sleeve gastrectomy and investigated... | ['Acyltransferases', 'Adaptation, Physiological', 'Adult', 'Aged', 'Blotting, Western', 'Body Mass Index', 'Calcium-Binding Proteins', 'DNA-Binding Proteins', 'Female', 'Gastric Mucosa', 'Ghrelin', 'Humans', 'Male', 'Middle Aged', 'Nerve Tissue Proteins', 'Nucleobindins', 'Obesity, Morbid'] | 23,515,787 | [['D08.811.913.050'], ['G07.025', 'G16.012.500'], ['M01.060.116'], ['M01.060.116.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D12.776.157.125'], ['D12.776.260'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oxidative damage to food and human serum proteins: Radical-mediated oxidation vs. glyco-oxidation. | This study compared a hydroxyl radical-generating system (HRGS) (0.05-0.2mM Fe3++0.6mM H2O2) and a glycation system (GLY) (0.05-0.2mM Fe3++0.05M glucose) for their ability to promote protein carbonylation and tryptophan depletion in myofibrillar proteins, ovalbumin, â-lactoglobulin, soy protein and human serum albumin.... | ['Animals', 'Blood Proteins', 'Dietary Proteins', 'Glucose', 'Humans', 'Hydrogen Peroxide', 'Hydroxyl Radical', 'Iron', 'Oxidation-Reduction', 'Plants', 'Protein Carbonylation'] | 29,934,144 | [['B01.050'], ['D12.776.124'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Identification of Xanthomonas citri ssp. citri host specificity genes in a heterologous expression host. | We provide the first conclusive evidence that Xanthomonas axonopodis pv. citri Asiatic strain (Xac-A) and, in particular, Xac-A(w), a unique citrus canker A strain isolated from Key lime in Wellington, Florida, induces a hypersensitive reaction (HR) in grapefruit leaves. Using the heterologous tomato pathogen X. perfor... | ['Bacterial Proteins', 'Citrus aurantiifolia', 'Citrus paradisi', 'Gene Library', 'Genes, Bacterial', 'Host-Pathogen Interactions', 'Lycopersicon esculentum', 'Molecular Sequence Data', 'Nucleic Acid Hybridization', 'Plant Diseases', 'Plant Leaves', 'Selection, Genetic', 'Sequence Analysis, DNA', 'Sequence Homology, Am... | 19,236,573 | [['D12.776.097'], ['B01.650.940.800.575.912.250.875.177.077'], ['B01.650.940.800.575.912.250.875.177.538'], ['G05.360.325'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G06.462', 'G16.527.200'], ['B01.650.940.800.575.912.250.908.500.322'], ['L01.453.245.667'], ['E05.393.661'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Recruitment of periventricular parietal regions in processing cluttered point-light biological motion. | Recent findings point to the existence of a cortical-subcortical parietal network that drives attention-related integration of features and elements. Here we ask whether the functioning of this network might be modulated by early periventricular lesions. To this end, a cohort of adolescents who were born premature with... | ['Adolescent', 'Attention', 'Female', 'Humans', 'Infant, Newborn', 'Leukomalacia, Periventricular', 'Male', 'Motion Perception', 'Nerve Net', 'Parietal Lobe', 'Photic Stimulation', 'Psychomotor Performance', 'Recruitment, Neurophysiological', 'Severity of Illness Index'] | 15,319,314 | [['M01.060.057'], ['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C10.228.140.300.700', 'C10.228.140.461.550', 'C14.907.253.612', 'C16.614.521.450'], ['F02.463.593.932.567'], ['A08.511'], ['A08.186.211.200.885.287.500.670'], ['E05.723.729'], ['F02.808', 'G11.427.700', 'G11.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cardiotocography supplemented with continuous fetal pH monitoring during labor. Effect on rate of obstetrical interventions and neonatal condition. | Continuous monitoring of the fetal scalp tissue pH (tpH) was performed in 96 consecutive cases. Of these 96, 72 (75%) had acceptable pH tracings which were used for the management of labor (series II). These 72 patients were compared with 72 patients from an earlier series (series I) of tpH monitoring in which pH was n... | ['Apgar Score', 'Delivery, Obstetric', 'Electrodes', 'Female', 'Fetal Blood', 'Fetal Distress', 'Fetal Heart', 'Fetal Monitoring', 'Heart Rate', 'Humans', 'Hydrogen-Ion Concentration', 'Infant, Newborn', 'Pregnancy', 'Scalp'] | 7,148,410 | [['E01.370.600.050'], ['E04.520.252'], ['E07.305.250'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['C23.888.380'], ['A07.541.278', 'A16.378.303'], ['E01.370.378.230', 'E01.370.520.230'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.703.520'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Use of beta-lactamase from Bacillus licheniformis 749/C for solid-phase immunoenzyme analysis]. | beta-Lactamase from Bacillus licheniformis 749/c was used as a marker for ELISA. Conjugates of the beta-lactamase with the capsule antigen of the plague causative agent and with the monoclonal antibodies to it were prepared by glutaric aldehyde "linking". The conjugates preserved high immunospecific and beta-lactamase ... | ['Antibodies, Monoclonal', 'Antigens, Bacterial', 'Bacillus', 'Immunoenzyme Techniques', 'Indicators and Reagents', 'Yersinia pestis', 'beta-Lactamases'] | 3,904,622 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.161'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D27.720.470.410']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interaction of cyclosporine A and nonsteroidal anti-inflammatory drugs on renal function in patients with rheumatoid arthritis. | PURPOSE: To determine the additive renal effects of nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclosporine A (CYA) in patients with rheumatoid arthritis (RA) and to determine the effects of CYA on active RA.PATIENTS AND METHODS: Eleven patients with RA refractory to other agents were treated separately for 2-we... | ['Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Arthritis, Rheumatoid', 'Cyclosporine', 'Drug Interactions', 'Drug Therapy, Combination', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Renal Circulation'] | 1,415,303 | [['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G07.690.773.968'], ['E02.319.310'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of triple antibiotic paste removal by different irrigation procedures. | INTRODUCTION: Regenerative endodontics aims to re-establish a functional pulp-dentin complex. First, the root canal system is disinfected primarily by irrigants and medicaments. Triple antibiotic paste (TAP), a commonly used intracanal medicament, has been shown to be directly toxic to stem cells at concentrations grea... | ['Anti-Bacterial Agents', 'Calcium Hydroxide', 'Calcium Radioisotopes', 'Ciprofloxacin', 'Dental Pulp Cavity', 'Dentin', 'Equipment Design', 'Humans', 'Iodine Radioisotopes', 'Metronidazole', 'Minocycline', 'Needles', 'Root Canal Irrigants', 'Root Canal Preparation', 'Syringes', 'Therapeutic Irrigation', 'Tooth Apex', ... | 25,069,927 | [['D27.505.954.122.085'], ['D01.045.250.313', 'D01.146.335', 'D01.248.497.158.459.150'], ['D01.268.552.100.500.325', 'D01.496.098.325', 'D01.496.749.113', 'D01.552.539.288.500.325'], ['D03.633.100.810.835.322.186'], ['A14.549.167.900.265'], ['A14.549.167.900.280'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
New insight into the autoimmunogenicity of the complement protein C1q. | C1q along with its physiological role in maintenance of homeostasis and normal function of the immune system is involved in pathological conditions associated with repetitive generation of anti-C1q autoantibodies. The time and events that cause their first appearance are still unknown. We addressed this issue by analyz... | ['Autoimmunity', 'Collagen', 'Complement C1q', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Health', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Lupus Nephritis', 'Male', 'Pregnancy', 'Protein Structure, Tertiary'] | 21,159,384 | [['G12.450.192'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.776.124.486.274.050.270'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['N01.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.1... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Direct DNA delivery into zebrafish embryos employing tissue culture techniques. | The production of transfected fish embryos requires expertise in injecting the fertilized eggs and/or expensive equipment for electroporation or microprojectiles. This article demonstrates that by exposure to DNA constructs conjugated with transfecting reagents dechorionated Danio rerio embryos are capable of acquiring... | ['Animals', 'Culture Techniques', 'DNA', 'DNA-Binding Proteins', 'Embryo, Nonmammalian', 'Gene Expression', 'Green Fluorescent Proteins', 'Luciferases', 'Luminescent Proteins', 'Time Factors', 'Transfection', 'Zebrafish'] | 11,668,671 | [['B01.050'], ['E05.481.500'], ['D13.444.308'], ['D12.776.260'], ['A13.350', 'A16.331'], ['G05.297'], ['D12.776.532.265'], ['D08.811.682.517', 'D12.776.532.510'], ['D12.776.532'], ['G01.910.857'], ['E05.393.350.810', 'G05.728.860'], ['B01.050.150.900.493.200.244.828']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling. | Nasopharyngeal carcinoma (NPC) is a rare disease in children with good prognosis and high cure rate. Nevertheless, certain patients have an unfavorable prognosis due to development of refractory NPC that is unresponsive to any therapeutic strategies. The current study studies a case of a 17 years-old female with non-ke... | ['Adolescent', 'Biomarkers, Tumor', 'Child', 'Drug Resistance, Neoplasm', 'Female', 'Gene Expression Profiling', 'Herpesvirus 4, Human', 'Humans', 'Immunocompromised Host', 'Immunohistochemistry', 'Lymphocytes, Tumor-Infiltrating', 'Male', 'Nasopharyngeal Carcinoma', 'Neoplasm Recurrence, Local', 'Prognosis', 'Prospect... | 30,066,889 | [['M01.060.057'], ['D23.101.140'], ['M01.060.406'], ['G07.690.773.984.395'], ['E05.393.332'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of acute and chronic electroconvulsive shock on noradrenaline release in the rat hippocampus and frontal cortex. | 1. Changes in the extracellular content of endogenous noradrenaline (NA) in frontal cortex and hippocampus were determined by in vivo microdialysis following acute and chronic electroconvulsive shock (ECS) in rats anaesthetized with chloral hydrate. 2. Basal release of NA in the frontal cortex (4.9 +/- 0.3 pg/sample) d... | ['Adrenergic alpha-Antagonists', 'Animals', 'Cerebral Cortex', 'Dialysis', 'Dioxanes', 'Electroshock', 'Frontal Lobe', 'Hippocampus', 'Idazoxan', 'Male', 'Norepinephrine', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic, alpha'] | 1,356,561 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['E05.196.353', 'G02.186'], ['D03.383.188'], ['E05.723.402.403', 'F04.669.224'], ['A08.186.211.200.885.287.500.270'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D03.383.129.308.428', 'D03.38... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A twin arginine signal peptide and the pH gradient trigger reversible assembly of the thylakoid [Delta]pH/Tat translocase. | The thylakoid DeltapH-dependent/Tat pathway is a novel system with the remarkable ability to transport tightly folded precursor proteins using a transmembrane DeltapH as the sole energy source. Three known components of the transport machinery exist in two distinct subcomplexes. A cpTatC-Hcf106 complex serves as precur... | ['Arginine', 'Cross-Linking Reagents', 'Dipeptides', 'Escherichia coli Proteins', 'Hydrogen-Ion Concentration', 'Macromolecular Substances', 'Membrane Proteins', 'Membrane Transport Proteins', 'Models, Biological', 'Peas', 'Plant Proteins', 'Plasmids', 'Protein Binding', 'Protein Sorting Signals', 'Protein Transport', ... | 11,956,224 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D27.720.470.410.210'], ['D12.644.456.345'], ['D12.776.097.275'], ['G02.300'], ['D05'], ['D12.776.543'], ['D12.776.157.530', 'D12.776.543.585'], ['E05.599.395'], ['B01.650.940.800.575.912.250.401.630'], ['D12.776.765'], ['G05.360.600'], ['G02.111.679', 'G03.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial mapping of extracellular oxidant production by a white rot basidiomycete on wood reveals details of ligninolytic mechanism. | Oxidative cleavage of the recalcitrant plant polymer lignin is a crucial step in global carbon cycling, and is accomplished most efficiently by fungi that cause white rot of wood. These basidiomycetes secrete many enzymes and metabolites with proposed ligninolytic roles, and it is not clear whether all of these agents ... | ['Benzyl Alcohols', 'Half-Life', 'Hyphae', 'Lignin', 'Oxidants', 'Phanerochaete', 'Wood'] | 23,206,186 | [['D02.033.160', 'D02.455.426.559.389.140.200'], ['G01.910.405'], ['A19.687.400'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['D27.720.642', 'D27.888.569.540'], ['B01.300.179.120.570'], ['A18.450.500.500', 'J01.637.241.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
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