Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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CD133 positive U87 glioblastoma cells-derived exosomal microRNAs in hypoxia- versus normoxia-microenviroment. | Hypoxia is a major regulator of glioma development and aggressiveness. However, how CD133 positive U87 glioblastoma cells adapt to hypoxia and communicate with their surrounding microenvironment during tumor development remain important questions. Communication with host cells and stroma via exosomes represents one pat... | ['AC133 Antigen', 'Cell Hypoxia', 'Cell Line, Tumor', 'Cell Survival', 'Coculture Techniques', 'Endothelial Cells', 'Exosomes', 'Glioblastoma', 'Humans', 'MicroRNAs', 'Microarray Analysis', 'Microscopy, Electron, Transmission', 'Microvessels', 'Tumor Microenvironment'] | 28,948,499 | [['D12.776.395.550.007', 'D12.776.543.550.023'], ['G03.197.300', 'G04.270.300'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['E05.481.500.374'], ['A11.436.275'], ['A11.284.295.588.750', 'A11.284.430.214.190.875.190.880.495'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine. | The critical micelle concentrations (CMC) of lysophosphatidic acid (LPA) and sphingosylphosphorylcholine (SPC) were measured by isothermal titration calorimetry. The CMC of LPA decreases with salt concentration and acyl chain length. In water at 25 degrees C, the CMC values of 1-acyl-2-lyso-sn-glycero-3-phosphatidic ac... | ['Lysophospholipids', 'Micelles', 'Molecular Structure', 'Phosphorylcholine', 'Sodium Chloride', 'Sphingosine', 'Water'] | 15,172,836 | [['D10.570.755.375.760.550'], ['D05.374', 'D26.255.560'], ['G02.111.570', 'G02.466'], ['D02.092.877.883.333.700', 'D02.675.276.232.700'], ['D01.210.450.150.875', 'D01.857.650'], ['D02.033.100.700', 'D02.033.455.843', 'D02.092.063.700'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transformation of triclosan and triclocarban in soils and biosolids-applied soils. | Triclosan (TCS) and triclocarban (TCC), widely used as antibacterial agents, have been frequently detected in biosolids. Biosolids land application may introduce pharmaceuticals and personal care products (PPCPs) such as TCS and TCC into the environment. Microcosm studies were conducted to investigate TCS and TCC trans... | ['Anti-Bacterial Agents', 'Carbanilides', 'Environmental Monitoring', 'Refuse Disposal', 'Soil Pollutants', 'Triclosan'] | 20,830,900 | [['D27.505.954.122.085'], ['D02.065.199.326', 'D02.065.950.681.202', 'D02.092.146.113.326', 'D02.455.426.559.389.703.202'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['D27.888.284.756'], ['D02.355.726.900', 'D02.455.426.559.389.657.654.900']] | ['Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A novel approach to rapid rewarming of a frostbitten extremity: The sous vide method. | BACKGROUND: Rapid rewarming of an acutely frostbitten extremity has been the standard treatment for nearly 60 years, however, there are no existing practical recommendations to create a warm water bath. Our study describes a novel approach to rapid rewarming using a sous vide cooking device to create and maintain a cir... | ['Animals', 'Cooking and Eating Utensils', 'Disease Models, Animal', 'Frostbite', 'Hot Temperature', 'Humans', 'Hydrotherapy', 'Swine', 'Water'] | 31,079,978 | [['B01.050'], ['J01.494.300', 'J01.576.423.200.300', 'J01.637.370'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C26.212.500', 'C26.417'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.4... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Large-Scale Conformational Transitions in Supercoiled DNA Revealed by Coarse-Grained Simulation. | Topological constraints, such as those associated with DNA supercoiling, play an integral role in genomic regulation and organization in living systems. However, physical understanding of the principles that underlie DNA organization at biologically relevant length scales remains a formidable challenge. We develop a co... | ['Algorithms', 'Computer Simulation', 'DNA, Bacterial', 'DNA, Superhelical', 'Escherichia coli', 'Hydrodynamics', 'Models, Genetic', 'Monte Carlo Method', 'Nucleic Acid Conformation', 'Transcription, Genetic'] | 27,705,758 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['D13.444.308.212'], ['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.156.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.342'], ['E05.599.395.397'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Beta-adrenoceptor-mediated cAMP accumulation in cardiac cells: effects of nebivolol. | The effects of nebivolol, the racemic mixture of the SRRR and RSSS enantiomers, on beta-adrenoceptor-mediated cAMP accumulation in living cardiac cells were compared to those of beta-adrenoceptor antagonists. Serum-free cultivation of cardiac cells from ventricles of 2 to 3-day-old Wistar rats resulted in a population ... | ['Adrenergic beta-Antagonists', 'Animals', 'Benzopyrans', 'Cells, Cultured', 'Cyclic AMP', 'Ethanolamines', 'Isoproterenol', 'Lung', 'Myocardium', 'Nebivolol', 'Norepinephrine', 'Rabbits', 'Rats', 'Receptors, Adrenergic, beta', 'Stereoisomerism'] | 2,575,531 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['D03.383.663.283', 'D03.633.100.150'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D02.033.100.291.439', 'D02.092... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age-related quantitative changes in mitochondria of satellite cell sheaths enveloping spinal ganglion neurons in the rabbit. | We studied mitochondria in the satellite cell sheaths which envelope the spinal ganglion neurons of rabbits aged 12, 42, and 79 months. While the mean cytoplasmic volume of satellite cell sheaths did not change significantly with age, the mean percentage of cytoplasmic volume occupied by mitochondria decreased with age... | ['Aging', 'Animals', 'Cytoplasm', 'Ganglia, Spinal', 'Microscopy, Electron', 'Mitochondria', 'Neurons', 'Rabbits', 'Satellite Cells, Perineuronal'] | 12,832,000 | [['G07.345.124'], ['B01.050'], ['A11.284.430.214'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['E01.370.350.515.402', 'E05.595.402'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.968.700'], ['A08.340.685', 'A08.637.685', 'A11.650.775']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indomethacin inhibits cell growth of medullary thyroid carcinoma by reducing cell cycle progression into S phase. | Indomethacin, a non-steroidal anti-inflammatory drug (NSAID), has been reported to inhibit the growth of medullary thyroid carcinoma (MTC) cells in vitro. However, the mechanism of inhibition of MTC cell growth by indomethacin and its potency have yet to be revealed. We examined the effect of indomethacin on three diff... | ['Antineoplastic Agents', 'Apoptosis', 'Calcitonin', 'Carcinoembryonic Antigen', 'Carcinoma, Medullary', 'Cell Cycle', 'Cell Line', 'Cell Proliferation', 'Cyclooxygenase Inhibitors', 'Dinoprostone', 'Gene Expression', 'Humans', 'Indoles', 'Indomethacin', 'Phosphorylation', 'Pyrroles', 'Retinoblastoma Protein', 'S Phase... | 18,791,128 | [['D27.505.954.248'], ['G04.146.954.035'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['C04.557.465.625.650.240.315', 'C04.557.470.200.025.370.31... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effectiveness of workplace dietary interventions: protocol for a systematic review and meta-analysis. | BACKGROUND: The lack of evidence of the role of workplaces as settings for behaviour change delivery and the failure to recognise and address the complexity of the work environment has been acknowledged. This systematic review and meta-analysis will identify the effectiveness of dietary interventions in the workplace f... | ['Diet', 'Feeding Behavior', 'Health Behavior', 'Health Promotion', 'Humans', 'Research Design', 'Systematic Reviews as Topic', 'Workplace'] | 26,842,069 | [['G07.203.650.240'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500', 'H01.770.644.728'], ['L01.178.682.759.575'], ['N01.824.245.925', 'N04.452.677.975']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Early results of cardiac transplantation at the Texas Heart Institute. | From July 1982 to November 1983 18 patients (one female) underwent orthotopic cardiac transplantation at the Texas Heart Institute. Prednisone and cyclosporin were used for maintenance immunosuppression in all patients. Cumulative follow up has now been for 90 patient months (0.75-20 months). Rejection occurred in 10 r... | ['Adult', 'Cyclosporins', 'Female', 'Graft Rejection', 'Heart Transplantation', 'Humans', 'Immunosuppression', 'Male', 'Middle Aged', 'Prednisone', 'Tissue Donors'] | 6,382,676 | [['M01.060.116'], ['D04.345.566.235', 'D12.644.641.235'], ['G12.875.545.328'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ['M01.060.116.630'], ['D04.210.500.745.432.719.702'], ['M01.898']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhancement Effect of Microbubble-Enhanced Ultrasound in Microwave Ablation in Rabbit VX2 Liver Tumors. | Objectives: One reason for the high recurrence and metastatic rates of tumors such as hepatocellular carcinoma (HCC) treated by microwave ablation (MWA) is the presence of residual foci in the tumor due to heat sink effect. Microbubble-enhanced ultrasound (MEUS) can noninvasively disrupt and block the tumor blood perfu... | ['Animals', 'Contrast Media', 'Liver', 'Liver Function Tests', 'Liver Neoplasms', 'Microbubbles', 'Microwaves', 'Necrosis', 'Perfusion', 'Rabbits', 'Temperature', 'Ultrasonography'] | 32,090,074 | [['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['A03.620'], ['E01.370.372.460'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E07.553'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['C23.550.717'], ['E05.680'], ['B01.050.150.900.649.313.968.700'], ['G01.906.595', 'G16.500.275.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Association of cardiovascular events and lipoprotein particle size: Development of a risk score based on functional data analysis. | BACKGROUND: Functional data is data represented by functions (curves or surfaces of a low-dimensional index). Functional data often arise when measurements are collected over time or across locations. In the field of medicine, plasma lipoprotein particles can be quantified according to particle diameter by ion mobility... | ['Aged', 'Cardiovascular Diseases', 'Case-Control Studies', 'Female', 'Humans', 'Lipoproteins', 'Male', 'Middle Aged', 'Particle Size', 'Proportional Hazards Models', 'Risk Factors'] | 30,845,215 | [['M01.060.116.100'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532', 'D12.776.521'], ['M01.060.116.630'], ['G02.712'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Osteoporosis in postmenopausal women (Mexico City): 1. Risk factors. | OBJECTIVE: To determine risk factors for osteoporosis in postmenopausal women from Mexico City.METHOD: The following prognostic variables for low bone density were analyzed in 400 postmenopausal women: age, body mass index (BMI), time since menopause (TM), previous and current hormone replacement therapy (HRT), previou... | ['Absorptiometry, Photon', 'Adult', 'Age Factors', 'Body Mass Index', 'Bone Density', 'Female', 'Humans', 'Logistic Models', 'Mexico', 'Middle Aged', 'Osteoporosis, Postmenopausal', 'Predictive Value of Tests', 'Prognosis', 'Risk Factors', 'Time Factors', 'Urban Population'] | 11,900,271 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Beta 2-microglobulin is not a bone cell mitogen. | During the purification of skeletal growth factor/insulin-like growth factor-II and transforming growth factor-beta (TGF beta) from EDTA extracts of bovine bone matrix significant mitogenic activity for cultured osteoblast (Ob)-like cells eluted in fractions that contained a nearly homogeneous peptide with a mol wt of ... | ['Amino Acid Sequence', 'Animals', 'Bone Marrow', 'Bone and Bones', 'Chromatography, High Pressure Liquid', 'Mitogens', 'Osmolar Concentration', 'Osteoblasts', 'Transforming Growth Factors', 'beta 2-Microglobulin'] | 2,661,210 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A15.382.216'], ['A02.835.232', 'A10.165.265'], ['E05.196.181.400.300'], ['D27.505.519.593.624'], ['G02.640'], ['A11.329.629'], ['D12.644.276.963', 'D12.776.467.960', 'D23.529.960'], ['D12.776.124.790.223.100', 'D12.776.377.715.182.100', 'D12.776.395.550.489.10... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The correlation between magnetic resonance imaging and ultrastructural patterns of brown adipose tissue. | The present paper reports on magnetic resonance imaging (MRI) at high spatial resolution of the brown adipose tissue (BAT) in laboratory rodents, in comparison with light and electron microscopy findings. Our aim was to assess whether MRI correlates with the expected ultrastructural differences between newborn and adul... | ['Adipose Tissue, Brown', 'Animals', 'Animals, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Mice', 'Neck', 'Rats', 'Rats, Inbred Strains', 'Scapula'] | 2,036,625 | [['A10.165.114.322'], ['B01.050'], ['B01.050.050.282'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['A01.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A02.835.232.087.783']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The development of cement and concrete additive: based on xylonic acid derived via bioconversion of xylose. | The present work attempted to utilize xylose by converting it to an aldonic acid. In the present study, xylose was converted to xyloni acid by using commercial glucose oxidase enzyme, palladium catalysis, and microbial bioconversion. The enzyme conversion was successfully done using a commercial glucose oxidase. The mi... | ['Acids', 'Biotransformation', 'Construction Materials', 'Gluconobacter oxydans', 'Glucose Oxidase', 'Materials Testing', 'Wood', 'Xylose'] | 18,563,642 | [['D01.029'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['J01.637.241'], ['B03.440.400.425.100.550.550', 'B03.660.050.755.050.415.550'], ['D08.811.682.047.239'], ['E05.570'], ['A18.450.500.500', 'J01.637.241.900'], ['D09.947.875.627.867']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Foundation of the bineme model for eukaryote chromosome]. | The fitness of two alternative chromosome models (unineme and bineme) to the vast body of biochemical, genetic, radiobiological and ultrastructural data is tested. Unineme model postulates the existence of only one DNA molecule (Watson--Crick double helix) per higher eukaryote chromosome at the G1 stage of the cell cyc... | ['Animals', 'Cell Cycle', 'Chromosomes', 'DNA', 'Genetic Code', 'Interphase', 'Models, Genetic'] | 7,070,381 | [['B01.050'], ['G04.144'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['D13.444.308'], ['G05.360.335'], ['G04.144.500'], ['E05.599.395.397']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of beta-catenin, p63 and CD34 in hair follicles during the course of androgenetic alopecia. | During the hair growth cycle, the hair follicle appears to recapitulate part of its embryogenesis where both beta-catenin and p63 participate. The aim of the present study was to investigate the hypothesis that beta-catenin and p63 protein may be involved in the pathogenesis of androgenetic alopecia. Second, expression... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Alopecia', 'Antigens, CD34', 'Gene Expression Regulation', 'Hair Follicle', 'Humans', 'Immunohistochemistry', 'Male', 'Membrane Proteins', 'Middle Aged', 'beta Catenin'] | 16,133,456 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C17.800.329.937.122', 'C23.300.035'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['G05.308'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhaled nitric oxide and intravenous magnesium sulphate for the treatment of persistent pulmonary hypertension of the newborn. | INTRODUCTION: The aim of this study was to compare the response and survival rates of term infants with persistent pulmonary hypertension of the newborn (PPHN) on high frequency oscillatory ventilation (HFOV) treated with either inhaled nitric oxide (iNO) or intravenous magnesium sulphate (MgSO4).METHODS: This was a ra... | ['Administration, Inhalation', 'Female', 'High-Frequency Ventilation', 'Humans', 'Infant, Newborn', 'Infusions, Intravenous', 'Intention to Treat Analysis', 'Magnesium Sulfate', 'Male', 'Nitric Oxide', 'Persistent Fetal Circulation Syndrome', 'Respiratory Therapy', 'Survival Analysis', 'Vasodilator Agents'] | 20,358,154 | [['E02.319.267.050'], ['E02.041.625.508', 'E02.880.820.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E05.318.372.250.250.365.500.500', 'N05.715.360.330.250.250.365.500.500', 'N06.850.520.450.250.250.365.500.500'], ['D01.524.550', 'D01.875.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lung health care for Aboriginal and Torres Strait Islander Queenslanders: breathing easy is not so easy. | OBJECTIVES: In Aboriginal and Torres Strait Islander peoples in Queensland, to (a) determine the disease burden of common chronic lung diseases and (b) identify areas of need with respect to lung health services.METHODS: Literature reviews and analyses of hospitalisation and mortality data were used to describe disease... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Health Care Surveys', 'Health Policy', 'Health Services Accessibility', 'Health Workforce', 'Humans', 'Infant', 'Interviews as Topic', 'Lung Diseases', 'Middle Aged', 'Oceanic Ancestry Group', 'Primary Health Care', 'Queensland', 'Young Adult'] | 22,126,958 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N04.590.374.350', 'N05.300.430'], ['N02.350', 'N04.452.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Comparison Between Manual Auditing and a Natural Language Process With Machine Learning Algorithm to Evaluate Faculty Use of Standardized Reports in Radiology. | PURPOSE: When implementing or monitoring department-sanctioned standardized radiology reports, feedback about individual faculty performance has been shown to be a useful driver of faculty compliance. Most commonly, these data are derived from manual audit, which can be both time-consuming and subject to sampling error... | ['Documentation', 'Faculty, Medical', 'Humans', 'Machine Learning', 'Medical Audit', 'Natural Language Processing', 'Radiology Information Systems', 'Software'] | 29,269,244 | [['L01.453.245'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['N04.761.700.250.500', 'N05.700.175.500'], ['L01.224.050.375.580'], ['N04.452.515.825'], ['L01.224.900']] | ['Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Becker's nevus syndrome. | Becker's nevus (BN) is a unilateral hyperpigmented, often hairy, cutaneous hamartoma, with geographic borders. It is usually localized on the shoulder, anterior chest, scapula, or upper arm, but there have been reports of BN in other areas (eg, lower extremities, face). In most cases, the lesion appears in late childho... | ['Adolescent', 'Axilla', 'Breast', 'Female', 'Follow-Up Studies', 'Humans', 'Mammaplasty', 'Nevus, Pigmented', 'Skin Neoplasms', 'Syndrome'] | 11,534,913 | [['M01.060.057'], ['A01.378.800.090'], ['A01.236'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['C04.557.665.560.615'], ['C04.588.805', 'C17.800.882'], ['C23.550.288.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Small Molecule Microarray Based Discovery of PARP14 Inhibitors. | Poly(ADP-ribose) polymerases (PARPs) are key enzymes in a variety of cellular processes. Most small-molecule PARP inhibitors developed to date have been against PARP1, and suffer from poor selectivity. PARP14 has recently emerged as a potential therapeutic target, but its inhibitor development has trailed behind. Herei... | ['Drug Discovery', 'High-Throughput Screening Assays', 'Humans', 'Microarray Analysis', 'Poly(ADP-ribose) Polymerase Inhibitors', 'Poly(ADP-ribose) Polymerases', 'Small Molecule Libraries', 'Structure-Activity Relationship'] | 27,918,638 | [['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['E05.916.680'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.588.570'], ['D27.505.519.389.739', 'D27.505.954.248.692'], ['D08.811.913.400.725.115.690'], ['D27.720.470.765'], ['G02.111.830', 'G07.690.773.997']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A nine-segment influenza a virus carrying subtype H1 and H3 hemagglutinins. | Influenza virus genomic RNAs possess segment-specific packaging signals that include both noncoding regions (NCRs) and adjacent terminal coding region sequences. Using reverse genetics, an A/Puerto Rico/8/34 (A/PR/8/34) virus was rescued that contained a modified PB1 gene such that the PB1 packaging sequences were exch... | ['Animals', 'Female', 'Genome, Viral', 'Hemagglutinin Glycoproteins, Influenza Virus', 'Influenza A virus', 'Influenza Vaccines', 'Mice', 'Mice, Inbred C57BL', 'Orthomyxoviridae Infections', 'RNA, Viral', 'Reassortant Viruses', 'Recombination, Genetic', 'Viral Proteins', 'Virus Assembly'] | 20,519,387 | [['B01.050'], ['G05.360.340.358.840'], ['D12.776.964.970.880.345.500'], ['B04.820.480.968.405.400'], ['D20.215.894.899.302'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['C01.925.782.620'], ['D13.444.735.828'], ['B04.800'], ['G05.728'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An ab initio theoretical study of the stereoisomers of tetrahydrocannabinols. | An extensive theoretical study of the stereoisomers of tetrahydrocannabinols has been performed at the ab initio HF/6-31G* and B3LYP/6-31G* levels. Effects of solvation were calculated with the Onsager model (with full geometry optimization), SCRF with Tomasi's PCM, and isodensity polarization continuum models. Single-... | ['Computer Simulation', 'Dronabinol', 'Models, Molecular', 'Stereoisomerism', 'Thermodynamics'] | 11,349,815 | [['L01.224.160'], ['D02.455.849.090.810'], ['E05.599.595'], ['G02.607.445.682'], ['G01.906']] | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acute kidney injury from immune checkpoint inhibitor use. | Immune checkpoint inhibitors are novel oncological medications, current classes of which include monoclonal antibodies that target inhibitory receptors cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), programmed death 1 protein (PD-1) and programmed death-ligand 1. While they are novel in their ability to treat ca... | ['Acute Kidney Injury', 'Aged', 'Antibodies, Monoclonal', 'Antineoplastic Agents, Immunological', 'Diagnosis, Differential', 'Humans', 'Male', 'Melanoma', 'Nephritis, Interstitial', 'Skin Neoplasms', 'Steroids'] | 31,653,633 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248.384'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased intracellular cyclic AMP levels block PKC-mediated T cell activation by inhibition of c-jun transcription. | Antigen binding to specific receptors on T cells (TCR) results in a rapid and transient phosphoinositide hydrolysis followed by activation of protein kinase C (PKC). Activators of adenylate cyclase or cell permeable cyclic AMP (cAMP) derivatives antagonize this effect and inhibit T cell activation by interfering with p... | ['Animals', 'Blotting, Northern', 'Bucladesine', 'DNA-Binding Proteins', 'Female', 'Ionomycin', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred BALB C', 'Mitogens', 'Protein Kinase C', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-fos', 'Proto-Oncogene Proteins c-jun', 'RNA, Messenger', 'T-Lymphocytes', 'Tetrade... | 1,851,138 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['D12.776.260'], ['D10.251.355.391'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Levels of small molecules and enzymes in the mother cell compartment and the forespore of sporulating Bacillus megaterium. | We have determined the amounts of a number of small molecules and enzymes in the mother cell compartment and the developing forespore during sporulation of Bacillus megaterium. Significant amounts of adenosine 5'-triphosphate and reduced nicotinamide adenine dinucleotide were present in the forespore compartment before... | ['Adenine Nucleotides', 'Adenosine Triphosphate', 'Amino Acids', 'Bacillus megaterium', 'Bacterial Proteins', 'Citric Acid Cycle', 'DNA, Bacterial', 'Glycerophosphates', 'NAD', 'Peptide Hydrolases', 'Picolinic Acids', 'RNA, Bacterial', 'Spores, Bacterial'] | 193,830 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.125'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['D12.776.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of heart failure on hip fracture outcomes: a population-based study. | BACKGROUND: Hip fracture and heart failure are becoming more prevalent conditions in hospitalized patients. Despite differences in postoperative outcomes from other intermediate risk procedures, guidelines classify hip fracture repair as an intermediate risk operation.OBJECTIVE: This population-based study sought to ex... | ['Aged, 80 and over', 'Confidence Intervals', 'Female', 'Heart Failure', 'Hip Fractures', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Male', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Preoperative Care', 'Prevalence', 'Retrospective Studies', 'Risk Assessment', 'United States'] | 22,042,721 | [['M01.060.116.100.080'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C14.280.434'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Functional Role of Bacteria from Invasive Phragmites australis in Promotion of Host Growth. | We hypothesize that bacterial endophytes may enhance the competitiveness and invasiveness of Phragmites australis. To evaluate this hypothesis, endophytic bacteria were isolated from P. australis. The majority of the shoot meristem isolates represent species from phyla Firmicutes, Proteobacteria, and Actinobacteria. We... | ['Antibiosis', 'Bacteria', 'Biomass', 'Fungi', 'Indoleacetic Acids', 'Lipopeptides', 'Nitrogen Fixation', 'Phosphates', 'Plant Roots', 'Poaceae', 'Soil Microbiology', 'Symbiosis'] | 27,260,154 | [['G06.550.050', 'G16.062'], ['B03'], ['G16.500.275.157.100', 'N06.230.124.100'], ['B01.300'], ['D03.066.288', 'D03.633.100.473.404'], ['D10.477', 'D12.644.365'], ['G02.111.071.630', 'G02.111.587.750', 'G02.607.560.750', 'G03.087.630', 'G06.625', 'G16.500.768.600'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Reducing drug administration errors using "Do not disturb" tabards and signs]. | INTRODUCTION: According to the report published by the Italian Ministry Health on sentinel events collected between 2005-2010, 873 events were reported, of which 4% (about 35) led to mortality, coma or serious functional disorders due to drug administration errors made by nurses. The link between interruptions and pati... | ['Delivery of Health Care', 'Hospitals, Teaching', 'Humans', 'Italy', 'Medication Errors', 'Nursing Staff, Hospital', 'Patient Safety', 'Quality of Health Care'] | 30,029,297 | [['N04.590.374', 'N05.300'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E02.319.529', 'N02.421.450.500'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['N06.850.135.060.075.399'], ['N04.761', 'N05.715']] | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of estrogen treatment on coagulation and fibrinolysis in postmenopausal women. With special reference to cold activation of factor VII. | Estriol (E3) and estradiol (E2) was given to 81 women with perimenopausal complaints. Venous blood was sampled before and after 2 weeks' treatment. In plasma coagulation and fibrinolysis the most marked estrogen effects were seen within the extrinsic coagulation system, with increased Thrombotest and Normotest activiti... | ['Administration, Oral', 'Blood Coagulation', 'Cold Temperature', 'Dose-Response Relationship, Drug', 'Estradiol', 'Estriol', 'Factor VII', 'Female', 'Fibrinolysis', 'Humans', 'Injections, Intramuscular', 'Kallikreins', 'Kinins', 'Menopause', 'Protease Inhibitors'] | 738,649 | [['E02.319.267.100'], ['G09.188.390.150'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G07.690.773.875', 'G07.690.936.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500.365.415.331', 'D06.472.334.851... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The metastasis suppressor CD82/KAI1 inhibits fibronectin adhesion-induced epithelial-to-mesenchymal transition in prostate cancer cells by repressing the associated integrin signaling. | The transmembrane protein CD82/KAI1 suppresses the metastatic potential of various cancer cell types. Moreover, decrease or loss of CD82 expression is closely associated with malignancy and poor prognosis in many human cancers including prostate cancer. Despite intense scrutiny, the mechanisms underlying the metastasis... | ['Cadherins', 'Cell Line, Tumor', 'Cell Movement', 'Epithelial-Mesenchymal Transition', 'Fibronectins', 'Focal Adhesion Kinase 1', 'Humans', 'Integrin alpha3beta1', 'Integrin alpha5beta1', 'Kangai-1 Protein', 'Male', 'Neoplasm Metastasis', 'Prostate', 'Prostatic Neoplasms', 'Protein-Serine-Threonine Kinases', 'Signal T... | 27,926,483 | [['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.356.500'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D08.811.913.696.620.682.725.049.500', 'D12.776.744.493'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RASOnD-a comprehensive resource and search tool for RAS superfamily oncogenes from various species. | BACKGROUND: The Ras superfamily plays an important role in the control of cell signalling and division. Mutations in the Ras genes convert them into active oncogenes. The Ras oncogenes form a major thrust of global cancer research as they are involved in the development and progression of tumors. This has resulted in t... | ['Databases, Genetic', 'Genomics', 'Internet', 'Proteomics', 'User-Computer Interface', 'ras Proteins'] | 21,729,256 | [['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['L01.224.230.110.500'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['L01.224.900.910'], ['D08.811.277.040.330.300.400.500', 'D12.644.360.525.500', 'D12.776.157... | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. | High levels of IL-6 were found in 50% of 114 patients with primary ovarian cancer. IL-6 sensitivity was lower than that of CA 125, and the combination of both assays did not increase the sensitivity of CA 125 alone. However, elevated IL-6 serum levels were correlated with a poor prognosis since patients with low IL-6 l... | ['Adult', 'Aged', 'Ascites', 'Biomarkers, Tumor', 'CA-125 Antigen', 'Female', 'Humans', 'Interleukin-6', 'Life Tables', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Proteins', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Prognosis', 'Sensitivity and Specificity', 'Survival Analysis'] | 7,841,052 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.081'], ['D23.101.140'], ['D12.776.395.560.631.050', 'D23.050.285.050.225', 'D23.050.550.325.225', 'D23.101.140.075.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E05.318.308.985.475... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relevance of the number of positive bottles in determining clinical significance of coagulase-negative staphylococci in blood cultures. | Coagulase-negative staphylococci (CNS) are the most commonly isolated contaminants from blood cultures, yet they frequently cause true infections. Determining the clinical significance of CNS is difficult, and clinicians often consider the number of positive bottles within a set of blood culture bottles in their assess... | ['Bacteriological Techniques', 'Blood', 'Coagulase', 'Culture Media', 'Equipment Contamination', 'Humans', 'Sepsis', 'Staphylococcal Infections', 'Staphylococcus'] | 11,526,163 | [['E01.370.225.875.150', 'E05.200.875.150'], ['A12.207.152', 'A15.145'], ['D08.811.277.656.300.174', 'D12.776.097.181'], ['D27.720.470.305', 'E07.206'], ['N06.850.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.757', 'C23.550.470.790.500'], ['C01.150.252.410.868'], ['B03.300.390.400.800.750', 'B03.353.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conformational transitions in fluorescein-labeled (Na,K)ATPase reconstituted into phospholipid vesicles. | Fluorescein-labeled (Na,K)ATPase reconstituted into phospholipid vesicles has been used to study conformational transitions. Addition of K+ or Na+ to the vesicle medium induces fluorescence changes characteristic of the E2(K) or E1Na states of fluorescein-labeled (Na,K)ATPase (Karlish, S.J.D. (1980) J. Bioenerg. Biomem... | ['Animals', 'Choline', 'Fluorescein-5-isothiocyanate', 'Fluoresceins', 'Kidney', 'Lithium', 'Potassium', 'Protein Conformation', 'Sodium', 'Sodium-Potassium-Exchanging ATPase', 'Spectrometry, Fluorescence', 'Substrate Specificity', 'Swine', 'Thiocyanates'] | 3,009,450 | [['B01.050'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.400', 'D04.711.347.400'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['A05.810.453'], ['D01.268.549.450', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hormone-induced phosphorylation of the plasma membrane calcium pump in cultured aortic endothelial cells. | The regulation of the plasma membrane Ca2+ pump by hormones via phosphorylation in intact cells has not been clearly established. We now present evidence that the Ca2+ pump is phosphorylated on both serine and threonine residues in unstimulated and stimulated cultured rat aortic endothelial cells. Among the stimuli tes... | ['Animals', 'Aorta, Thoracic', 'Biological Transport, Active', 'Calcium', 'Cell Membrane', 'Cells, Cultured', 'Cyclic AMP', 'Endothelium, Vascular', 'Enzyme Activation', 'Hormones', 'Peptide Mapping', 'Phosphoproteins', 'Phosphorylation', 'Phosphoserine', 'Phosphothreonine', 'Protein Kinase C', 'Protein Kinases', 'Rats... | 1,654,840 | [['B01.050'], ['A07.015.114.056.372'], ['G03.143.310'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A07.015.700.500', 'A10.272.491.355'], ['G02.111.263', 'G03.328'], ['D06.472', '... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arginyl-glycyl-aspartic acid sequences and fibrinogen binding to platelets. | Human fibrinogen has an Arg-Gly-Asp-Ser (RGDS) sequence at residues 572-575 of its A alpha-chain. Although RGDS-containing peptides inhibit fibrinogen binding to stimulated platelets, these peptides also inhibit platelet binding of human fibrinogen fragment X and rat fibrinogen, which lack RGDS sequences corresponding ... | ['Adenosine Diphosphate', 'Amino Acid Sequence', 'Blood Platelets', 'Cell Adhesion', 'Fibrinogen', 'Humans', 'Oligopeptides', 'Platelet Aggregation', 'Protein Binding', 'Receptors, Cell Surface', 'Serine'] | 3,036,276 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['G02.111.570.060', 'L01.453.245.667.060'], ['A11.118.188', 'A15.145.229.188'], ['G04.022'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.456'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Delayed enhancement on cardiac magnetic resonance and clinical, morphological, and electrocardiographical features in hypertrophic cardiomyopathy. | BACKGROUND: The clinical, morphological, and electrocardiographical relevance of delayed enhancement (DE) in cardiac magnetic resonance (CMR) was studied in patients with hypertrophic cardiomyopathy (HCM).METHODS AND RESULTS: A total of 56 patients underwent both gadolinium-enhanced CMR and 12-lead electrocardiogram. T... | ['Cardiomyopathy, Hypertrophic', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Heart Ventricles', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Retrospective Studies', 'Ventricular Function, Left'] | 19,477,402 | [['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Polypyrrole Composite Nanoparticles with Morphology-Dependent Photothermal Effect and Immunological Responses. | Polypyrrole composite nanoparticles with controlled shape are synthesized, which exhibit a morphology-dependent photothermal effect: the raspberry-like composite nanoparticles have a much better photothermal effect than the spherical ones, and the immune responses to the nanocomposites are also dependent on their morph... | ['Animals', 'Antigens, CD', 'Cell Line, Tumor', 'Cell Survival', 'Dendritic Cells', 'Humans', 'Hyperthermia, Induced', 'Immunity', 'Mice, Inbred BALB C', 'Mice, Nude', 'Nanoparticles', 'Phototherapy', 'Polymers', 'Pyrroles', 'Temperature'] | 26,701,670 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['G12.450'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Myocardial demands of atrial-triggered versus fixed-rate ventricular pacing in patients with complete heart block. | Hemodynamics, myocardial oxygen consumption, and lactate concentration were determined by cardiac catheterization at rest and during exercise in eight patients treated with AV universal pacemakers (DDD) for high degree AV block. The pulse generator was alternately programmed in ventricular inhibited (VVI) or atrial syn... | ['Aged', 'Aged, 80 and over', 'Cardiac Output', 'Cardiac Pacing, Artificial', 'Female', 'Heart Atria', 'Heart Block', 'Heart Ventricles', 'Humans', 'Lactates', 'Lactic Acid', 'Male', 'Myocardium', 'Oxygen Consumption', 'Physical Exertion', 'Stroke Volume'] | 2,444,940 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E02.331.200'], ['A07.541.358'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['A02.633.580', 'A07.541... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Competing causes of death and medical comorbidities among patients with human papillomavirus-positive vs human papillomavirus-negative oropharyngeal carcinoma and impact on adherence to radiotherapy. | IMPORTANCE: Survival of patients with head and neck cancer can be affected by competing causes of mortality, as well as comorbidities that result in radiation treatment interruptions.OBJECTIVE: To discern how differences in preexisting medical and psychosocial comorbidities potentially influence adherence to radiation ... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Cause of Death', 'Comorbidity', 'Female', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Oropharyngeal Neoplasms', 'Papillomaviridae', 'Patient Compliance', 'Prevalence', 'Retrospective Studies', 'Risk Factors'] | 24,526,276 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['M01.060.116... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chronic myelogenous leukemia in chronic phase transforming into acute leukemia under treatment with dasatinib 4 months after diagnosis. | We report a 64-year-old woman morphologically diagnosed with chronic myelogenous leukemia in the chronic phase. Despite having achieved a complete hematological response following treatment with dasatinib, she developed lymphoblastic crisis 4 months later. Blastic cells were in a CD45-negative and SSC-low fraction, and... | ['Acute-Phase Reaction', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Asparaginase', 'Blast Crisis', 'Cyclophosphamide', 'Dasatinib', 'Dexamethasone', 'Disease Progression', 'Doxorubicin', 'Female', 'Fetal Blood', 'Humans', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Middle Aged'... | 26,662,559 | [['C23.550.470.099'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D08.811.277.087.116'], ['C04.557.337.539.250.100', 'C04.697.098.500.110', 'C15.378.190.636.370.100', 'C23.550.727.098.500.110'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02.886.675.184', 'D03.383.12... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Design of 5' untranslated sequences in retroviral vectors developed for medical use. | Utilizing genetic modules of simple retroviruses, we have developed a novel generation of gene transfer vectors with improved therapeutic potential. In the 5' untranslated "leader" sequences, all AUG codons which may aberrantly initiate translation and all viral coding sequences were removed. Thus, the probability of e... | ["5' Untranslated Regions", 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Codon, Initiator', 'DNA, Viral', 'Drug Resistance, Microbial', 'Gene Expression', 'Gene Transfer Techniques', 'Genetic Vectors', 'Humans', 'Introns', 'K562 Cells', 'Mice', 'Molecular Sequence Data', 'Mutagenesis', 'Retroviridae', 'Transgene... | 10,196,304 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355.225', 'G05.360.335.355.225', 'G05.360.340.024.340.137.190.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells. | Apoptin has been described to induce apoptosis in various human cancer cell lines, but not in normal cells, thus making it an interesting candidate for the development of novel therapeutic strategies. Apoptin was generated and cloned into several mammalian expression vectors. Transfection or microinjection of apoptin c... | ['Active Transport, Cell Nucleus', 'Apoptosis', 'Capsid Proteins', 'Cell Line, Tumor', 'Cell Nucleus', 'Cytoplasm', 'Gene Products, tat', 'Genetic Therapy', 'Genetic Vectors', 'Green Fluorescent Proteins', 'HeLa Cells', 'Humans', 'Kinetics', 'Luminescent Proteins', 'Neoplasms', 'Protein Structure, Tertiary', 'Recombina... | 14,691,460 | [['G03.143.310.100', 'G03.143.700.100'], ['G04.146.954.035'], ['D12.776.964.970.600.550'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['D12.776.260.755.199', 'D12.776.930.900.199', 'D12.776.964.900.750.750', 'D12.776.964.925.984.400'], ['E02.095.301'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Home nasal continuous positive airway pressure in infants with sleep-disordered breathing. | OBJECTIVE: To review our experience with home nasal continuous positive airway pressure (CPAP) in infants with small upper airways and abnormal breathing during sleep.STUDY DESIGN: Seventy-four infants with sleep-disordered breathing and narrow upper airways, as identified by nocturnal polygraphic recording and endosco... | ['Airway Obstruction', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Patient Compliance', 'Polysomnography', 'Positive-Pressure Respiration', 'Respiratory Tract Diseases', 'Severity of Illness Index', 'Sleep Apnea Syndromes', 'Sleep, REM'] | 8,523,187 | [['C08.618.846.185'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['E01.370.520.625'], ['E02.041.625.79... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibitory mechanism of N(G)-nitro-L-arginine on acetylcholine-induced depressor responses in dogs. | The significance of the blood pressure elevation caused by N(G)-nitro-L-arginine (L-NNA) to inhibitory mechanism of the drug on depressor responses to acetylcholine in anesthetized dogs was investigated. L-NNA (50 mg kg(-1), i.v.) elevated blood pressure to a plateau of 30-50 mm Hg above baseline level and shifted the ... | ['Acetylcholine', 'Animals', 'Atropine', 'Blood Pressure', 'Carbachol', 'Carcinogens', 'Cholinergic Agents', 'Cholinesterases', 'Dogs', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Female', 'Hydrazines', 'Male', 'Neostigmine', 'Nitroarginine', 'Vasodilator Agents'] | 10,414,440 | [['D02.092.211.111'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['D27.888.569.100'], ['D27.505.519.625.120', 'D27.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemically defined media for auxotyping of Campylobacter jejuni. | A set of chemically defined media has been developed for the cultivation of Campylobacter jejuni strains of human origin. A minimal medium, a complete medium and 5 different nutrient-deficient media (NDM1-NDM5) are described. Some of the strains investigated required L-methionine(lacking in NDM1), L-cystine and L-cyste... | ['Campylobacter fetus', 'Culture Media', 'Cysteine', 'Cystine', 'Feces', 'Hot Temperature', 'Humans', 'Hydrogen-Ion Concentration', 'Methionine', 'NAD', 'Pantothenic Acid', 'Phosphates', 'Potassium', 'Potassium Compounds', 'Thiamine'] | 4,060,921 | [['B03.440.180.325', 'B03.660.150.235.250.500.220'], ['D27.720.470.305', 'E07.206'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Treatment of an exposed breast implant by muscle flap and by fascia graft. | An exposed breast implant was salvaged on one occasion by a lateral muscle flap from the serratus anterior and a second time medially by a fascia lata graft. | ['Adult', 'Breast', 'Fascia', 'Fascia Lata', 'Female', 'Humans', 'Muscles', 'Postoperative Complications', 'Prostheses and Implants', 'Surgery, Plastic', 'Surgical Wound Infection', 'Transplantation, Autologous'] | 727,661 | [['M01.060.116'], ['A01.236'], ['A02.340', 'A10.165.425'], ['A02.340.424', 'A10.165.425.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['C23.550.767'], ['E07.695'], ['H02.403.810.788'], ['C01.947.692', 'C23.550.767.925'], ['E04.936.664']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Cochlear implant in a patient with dilatation of the endolymphatic sac and vestibular aqueduct]. | We present an 8 years patient old with a giant dilatation of the vestibular aqueduct associated with profound and progressive bilateral sensorineural hearing loss. The patient received a cochlear implant and during the surgery a pulsatile clear fluid via the cochleostomy was observed, without gusher. We present all the... | ['Child', 'Cochlear Implantation', 'Dilatation, Pathologic', 'Endolymphatic Sac', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Vestibular Aqueduct'] | 15,819,521 | [['M01.060.406'], ['E04.580.450.220', 'E04.650.220'], ['C23.300.325'], ['A09.246.300.909.957.360.701'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.246.300.909.957']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Women at risk: predictors of financial stress for retired women workers. | Research on women workers tends to neglect older workers, and much of the literature on retirement has focused on male experiences. This analysis uses data from the 1982 New Beneficiary Survey to examine financial stress in retirement for a sample of highly committed women workers. Separate regressions are done for mar... | ['Aged', 'Female', 'Humans', 'Logistic Models', 'Middle Aged', 'Poverty', 'Prejudice', 'Retirement', 'Risk Factors', 'Socioeconomic Factors', 'Women, Working'] | 1,778,492 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830.500.525', 'N06.850.520.830.600.800.450', 'N06.850.520.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[The role of the occupational physician in the prevention of the spreading of H5N1 virus avian influenza in exposed workers]. | BACKGROUND: Avian influenza caused by H5N1 virus can be transmitted to exposed workers from contact with infected poultry, and is thus, like other zoonoses, the responsibility of occupational physicians (OP). The high pathogenicity of H5N1 virus has caused a 30-75% mortality among infected humans. Most of those subject... | ['Animals', 'Birds', 'Humans', 'Influenza A Virus, H5N1 Subtype', 'Influenza in Birds', 'Influenza, Human', 'Laboratory Infection', 'Occupational Diseases', 'Occupational Exposure', 'Occupational Medicine', "Physician's Role"] | 17,009,673 | [['B01.050'], ['B01.050.150.900.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.500'], ['C01.925.782.620.300', 'C22.131.450'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['C01.503', 'C24.506'], ['C24'], ['N06.850.460.350.600'], ['H02.403.720.750.510'], ['F01.829.316.616.625... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Increased risk of anterior uveitis following herpes zoster: a nationwide population-based study. | OBJECTIVE: To investigate the relationship between herpes zoster (HZ) and the subsequent risk of anterior uveitis during the year following an HZ diagnosis, using a nationwide population-based data set.METHODS: This study used the Taiwan National Health Insurance Research Database. The study cohort consisted of 314,405... | ['Adolescent', 'Adult', 'Cohort Studies', 'Databases, Factual', 'Female', 'Follow-Up Studies', 'Herpes Zoster Ophthalmicus', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Population Groups', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk Factors', 'Taiwan', 'Uveitis, Anterior', 'Young Adult'] | 22,491,915 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.375.725.450', 'C01.925.256.466.930.750.466', 'C01.925.325... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Involvement of the colon in gastric and pancreatic processes]. | Using representative case studies the diagnostic problems of colonic infiltration in cases of gastric and pancreatic neoplastic or inflammatory lesions are discussed. Typical signs in both barium enema and ultrasonography lead to the detection of secondary bowel wall lesions. Characteristic intraperitoneal pathways of ... | ['Adenocarcinoma, Scirrhous', 'Aged', 'Barium Sulfate', 'Colonic Neoplasms', 'Female', 'Foreign-Body Reaction', 'Humans', 'Linitis Plastica', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Stomach Neoplasms', 'Tomography, X-Ray Computed'] | 6,299,913 | [['C04.557.470.200.025.095'], ['M01.060.116.100'], ['D01.103.075', 'D01.875.800.800.850.075'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C23.550.470.251', 'C26.392.560'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of varied pH, growth rate and temperature using controlled fermentation and batch culture on matrix assisted laser desorption/ionization whole cell protein fingerprints. | Rapid identification of microorganisms using matrix assisted laser desorption/ionization (MALDI) is a rapidly growing area of research due to the minimal sample preparation, speed of analysis and broad applicability of the technique. This approach relies on expressed biochemical markers, often proteins, to identify mic... | ['Bacterial Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Fermentation', 'Hydrogen-Ion Concentration', 'Microbiological Techniques', 'Peptide Mapping', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Temperature', 'Yersinia enterocolitica'] | 15,979,749 | [['D12.776.097'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G02.111.158.249', 'G03.191.249'], ['G02.300'], ['E01.370.225.875', 'E05.200.875'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['E05.196.566.755'], ['G01.906.595', 'G16.500.275.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid acute physiology scoring in transport systems. | A multi-institutional study was undertaken to define the predictive power for mortality of the Rapid Acute Physiology Score (RAPS) in a large and diverse group of transported patients. RAPS is a truncated version of the Acute Physiology and Chronic Health Evaluation (APACHE II) score that uses definitions and weighting... | ['Adult', 'Aged', 'Aircraft', 'Emergency Medical Services', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Predictive Value of Tests', 'Severity of Illness Index', 'Transportation of Patients'] | 2,209,039 | [['M01.060.116'], ['M01.060.116.100'], ['J01.937.285.100'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Detection and localization of virus-specific DNA by in situ hybridization of cells during infection and rapid transformation by the murine sarcoma-leukemia virus. | Cytological preparations of interphase nuclei and chromosomes from mouse 3T6 cells prepared at various times after infection with the murine sarcomaleukemia virus complex were hybridized with the [(3)H]DNA product of the viral RNA-directed DNA polymerase. While uninfected nuclei had an average of 4 autoradiographic gra... | ['Animals', 'Autoradiography', 'Cell Nucleus', 'Cell Transformation, Neoplastic', 'Cells, Cultured', 'Chromosomes', 'DNA, Viral', 'Gammaretrovirus', 'Heterochromatin', 'Karyotyping', 'Leukemia Virus, Murine', 'Mice', 'Nucleic Acid Hybridization', 'RNA-Directed DNA Polymerase', 'Sarcoma', 'Time Factors', 'Tritium'] | 4,139,710 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.251'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['D13.444.308.568'], ['B04.613.807.375', 'B04.820.650.375'], ['A11.284.430.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five-millimeter balloon trocar site herniation: report of two cases and review of literature. | Trocar site herniation is a well-known potential complication of minimally invasive surgery. We present the cases of two herniations after use of 5-mm non-bladed balloon trocars. In both patients, surgical management was required, with no subsequent sequelae to date. The hernias were attributed to excessive fascial str... | ['Aged', 'Aged, 80 and over', 'Female', 'Hernia, Ventral', 'Humans', 'Laparoscopy', 'Surgical Instruments'] | 23,714,747 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.707.374.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E07.858.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regional pulmonary function in patients with mitral stenosis in relation to haemodynamic data. | Central haemodynamics in 23 patients with mitral stenosis and 7 control subjects were compared with the results of regional lung perfusion studied by (133)Xe, pulmonary scintigraphy with (99)mTc-labelled macro-aggregates of albumin, and regional ventilation by (133)Xe.A close correlation was found between both methods ... | ['Adult', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve Stenosis', 'Pulmonary Circulation', 'Radioisotopes', 'Radiometry', 'Respiration', 'Technetium', 'Ventilation-Perfusion Ratio', 'Xenon'] | 5,420,077 | [['M01.060.116'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.484.517'], ['G09.330.100.770', 'G09.772.593'], ['D01.496.749'], ['E05.799'], ['G09.772.705'], ['D01.268.271.870', 'D01.268.556.843', 'D01.268.956.875', 'D01.496.749.305.870', 'D01.552.544.843'], ['E01.370.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos. | To investigate whether the human pro alpha 1(I) collagen chain could form an in vivo functional interspecies heterotrimer with the mouse pro alpha 2(I) collagen chain, we introduced the human COL1A1 gene into Mov13 mice which have a functional deletion of the endogenous COL1A1 gene. Transgenic mouse strains (HucI and H... | ['Animals', 'Blotting, Northern', 'Bone and Bones', 'Collagen', 'DNA', 'Embryo, Mammalian', 'Genes', 'Genes, Lethal', 'Humans', 'Macromolecular Substances', 'Mice', 'Mice, Mutant Strains', 'Mice, Transgenic', 'Mutation', 'Phenotype', 'Procollagen', 'RNA', 'Skin'] | 1,690,840 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A02.835.232', 'A10.165.265'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D13.444.308'], ['A16.254'], ['G05.360.340.024.340'], ['G05.360.340.024.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quality of life in high-functioning adults with autism spectrum disorder: The predictive value of disability and support characteristics. | Although the concept of quality of life has increasingly been used in the field of intellectual disabilities over the past three decades, the factors contributing to quality of life of persons with autism spectrum disorder (ASD) have received relatively little attention. In this study, disability and support characteri... | ['Adolescent', 'Adult', 'Autistic Disorder', 'Demography', 'Disability Evaluation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Quality of Life', 'Severity of Illness Index', 'Social Support', 'Wechsler Scales'] | 16,940,316 | [['M01.060.057'], ['M01.060.116'], ['F03.625.164.113.500'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Detection of Toxoplasma-specific IgM in cord blood sera by antibody-class capture enzyme-linked immunosorbent assay. | An antibody class capture (ACC) enzyme-linked immunosorbent assay (ELISA) utilizing an F(ab)2 conjugate was established and its specificity and reproducibility were determined. The test was further validated by comparing its results with those obtained by 2 overseas reference laboratories which used the indirect immuno... | ['Antigens, Protozoan', 'Australia', 'Enzyme-Linked Immunosorbent Assay', 'Fetal Blood', 'Fluorescent Antibody Technique', 'Humans', 'Hydrocephalus', 'Immunoglobulin M', 'Toxoplasma', 'Toxoplasmosis, Congenital'] | 3,912,711 | [['D23.050.293'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Identification and characterisation of regional variations in the material properties of ureter according to microstructure. | There are few previous studies on the elastic properties of ureter and most have been limited to essentially one-dimensional deformation measurements. The object of this study was, therefore, to identify regional variations in the multiaxial behaviour of rabbit ureter, subjected to in vitro inflation/extension testing ... | ['Adventitia', 'Animals', 'Anisotropy', 'Biomechanical Phenomena', 'Collagen', 'Elasticity', 'Elastin', 'Male', 'Models, Theoretical', 'Mucous Membrane', 'Pressure', 'Rabbits', 'Stress, Mechanical', 'Ureter'] | 23,439,210 | [['A07.015.057', 'A10.165.189'], ['B01.050'], ['G01.590.040', 'G02.050'], ['G01.154.090', 'G01.374.089'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.374.590'], ['D05.750.078.421', 'D12.776.860.300.350'], ['E05.599'], ['A10.615.550'], ['G01.374.715'], ['B01.050.150.900.649.313.968.700'], ['G01.374.835'], ['A05.81... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorodeoxyglucose positron emission tomography in leiomyosarcoma: imaging characteristics. | OBJECTIVE: Leiomyosarcoma, a malignant neoplasm of smooth muscle, accounts for 7% of the sarcomas. Patients with leiomyosarcoma tumors have an average survival of 5 years. These tumors, which are derived from mesenchymal tissues, are difficult to diagnose, and treatment options remain controversial. The relatively rare... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Leiomyosarcoma', 'Linear Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Positron-Emission Tomography'] | 19,440,162 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.455', 'C04.557.450.795.455'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
One Health proof of concept: Bringing a transdisciplinary approach to surveillance for zoonotic viruses at the human-wild animal interface. | As the world continues to react and respond inefficiently to emerging infectious diseases, such as Middle Eastern Respiratory Syndrome and the Ebola and Zika viruses, a growing transdisciplinary community has called for a more proactive and holistic approach to prevention and preparedness - One Health. Such an approach... | ['Animals', 'Animals, Wild', 'Communicable Diseases, Emerging', 'Global Health', 'Humans', 'Sentinel Surveillance', 'Zoonoses'] | 28,034,593 | [['B01.050'], ['B01.050.050.300'], ['C01.221.500', 'C23.550.291.531.750'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.700.650', 'E05.318.650', 'N05.715.360.300.800.438.625.650', 'N06.850.520.308.980.438.700.650', 'N06.850.520.699', 'N06.850.780.675.650'], ['C0... | ['Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Chronic myeloid leukemia in the Netherlands: a population-based study on incidence, treatment, and survival in 3585 patients from 1989 to 2012. | OBJECTIVE: To assess the impact and results of treatment of CML in the general population, we conducted a population-based, nationwide study on 3585 CML patients diagnosed between 1989 and 2012 in the Netherlands.METHODS: Patient demographics were obtained from the Netherlands Cancer Registry. Information on age, gende... | ['Antineoplastic Agents', 'Female', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Incidence', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Netherlands', 'Population Surveillance', 'Prognosis', 'Protein Kinase Inhibitors', 'Treatment Outcome'] | 26,519,944 | [['D27.505.954.248'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04.557.337.539.250', 'C15.378.190.636.370'], ['Z01.542.651'], ['E05.318.308.980.438.700', ... | ['Chemicals and Drugs [D]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Some pharmaceutical properties of 3-hydroxypropyl- and 2,3-dihydroxypropyl-beta-cyclodextrins and their solubilizing and stabilizing abilities. | 3-Hydroxypropyl- and 2,3-dihydroxypropyl-beta-cyclodextrins (3-HP- and DHP-beta-CyDs) with different degrees of substitution (D.S.) were prepared and their pharmaceutical properties were investigated. The aqueous solubility of 3-HP- and DHP-beta-CyDs was much higher than that of the parent beta-CyD and the dissolution ... | ['Cyclodextrins', 'Dextrins', 'Drug Stability', 'Excipients', 'Hemolysis', 'Humans', 'In Vitro Techniques', 'Irritants', 'Solubility', 'Starch'] | 2,766,408 | [['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['D05.750.078.562.855.375', 'D09.301.915.400', 'D09.698.365.855.400'], ['E05.916.330'], ['D26.650.700.419', 'D27.720.744.770.419'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D27.720.400', 'D27.888.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intraspecific allometry of standard metabolic rate in green iguanas, Iguana iguana. | To study the allometric relationship between standard metabolic rate and body mass (mass range 16-3627 g) in green iguanas, Iguana iguana (n=32), we measured rates of oxygen consumption (V(O(2))) at 30 degrees C during scotophase. The relationship could be described as: V(O(2))(ml h(-1))=0.478W(0.734). The resulting ma... | ['Acclimatization', 'Animals', 'Body Constitution', 'Female', 'Hot Temperature', 'Iguanas', 'Male', 'Models, Biological', 'Oxygen Consumption'] | 14,511,749 | [['G07.025.133', 'G16.012.500.133'], ['B01.050'], ['E01.370.600.115', 'G07.100'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.833.393.500'], ['E05.599.395'], ['G03.680']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fathers' motives for birth attendance. | Thirty-seven couples expecting their first child served as subjects in an open-ended interview and questionnaire study concerning fathers' motives for birth attendance. Both interview and questionnaire data confirm the fact that motives, beliefs, and expectations concerning paternal participation in labor and delivery ... | ['Adult', 'Delivery, Obstetric', 'Fathers', 'Female', 'Humans', 'Labor, Obstetric', 'Male', 'Mothers', 'Motivation', 'Object Attachment', 'Pregnancy'] | 3,682,948 | [['M01.060.116'], ['E04.520.252'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['F01.658', 'F01.752.543.500.750'], ['F02.739.794.624'], ['G0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Bone formation in TiO2 bone scaffolds in extraction sockets of minipigs. | The osteoconductive capacity of TiO(2) scaffolds was investigated by analysing the bone ingrowth into the scaffold structure following their placement into surgically modified extraction sockets in Gottingen minipigs. Non-critical size defects were used in order to ensure sufficient bone regeneration for the evaluation... | ['Animals', 'Bone Density', 'Bone Development', 'Female', 'Materials Testing', 'Swine', 'Swine, Miniature', 'Tissue Engineering', 'Titanium', 'Tomography'] | 22,395,069 | [['B01.050'], ['G11.427.100'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['E05.570'], ['B01.050.150.900.649.313.500.880'], ['B01.050.150.900.649.313.500.880.399.800'], ['E05.481.500.311.500', 'J01.293.069.249.500'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['E01.370.350.825']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
No evidence of linkage between Mitsuda reaction and the NRAMP1 locus. | Thirty sib-pairs were ascertained through unrelated lepromatous probands. They consisted of 22 healthy individuals and 8 leprosy patients. The Mitsuda reactions of all sibs were evaluated both macroscopically and histologically, and high molecular weight genomic DNA was extracted from the white blood cells of all sib-p... | ['Adult', 'Cation Transport Proteins', 'Genetic Linkage', 'Genetic Predisposition to Disease', 'Humans', 'Lepromin', 'Leprosy', 'Middle Aged', 'Mycobacterium leprae', 'Nuclear Family'] | 11,757,172 | [['M01.060.116'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['G05.348'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D23.050.161.386'], ['C01.150.252.410.040.552.475.371'], ['M01.060.116.630'], ['B03.510.024.962.500.502', 'B03.510.460.400.410.552.552.502'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Lectin immuno tests: quantitation and titration of antigens and antibodies using lectin-antibody conjugates. | We have investigated the possibility of using lectin-antibody conjugates as general reagents in immunological procedures requiring a labeled antigen or antibody. Using these conjugates, labeling is achieved through saccharide binding sites of lectins which operate as acceptors for glycoconjugate marker substances added... | ['Animals', 'Antibodies', 'Antigen-Antibody Complex', 'Antigens', 'Concanavalin A', 'Erythrocytes', 'Escherichia coli', 'Immunoenzyme Techniques', 'Immunologic Techniques', 'Immunosorbent Techniques', 'Rabbits', 'Sheep'] | 7,007,506 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D23.050'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of seven measures of sickness absence based on data from three counties in Sweden. | The objective was to compare the applicability of and results provided by the two measures of sickness absence used most often within the Swedish social insurance administration (that is, unadjusted sick-leave rate and adjusted sick-leave rate) and five measures suggested by epidemiological researchers. Data consisted ... | ['Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sick Leave', 'Sweden'] | 16,788,261 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N01.824.417.700.662', 'N04.452.677.800.662'], ['Z01.542.816.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mortality following emergency groin hernia surgery in Denmark. | PURPOSE: The mortality following emergency groin hernia repair in Denmark is more than twice as high (7%) as in comparable countries. This article describes in detail the population that died following emergency herniotomy in order to identify aspects of care that may improve outcome.METHODS: Patients > or =18 years of... | ['Abdomen, Acute', 'Aged', 'Aged, 80 and over', 'Databases as Topic', 'Denmark', 'Emergencies', 'Female', 'Groin', 'Hernia', 'Herniorrhaphy', 'Humans', 'Male', 'Middle Aged', 'Surgical Procedures, Operative'] | 20,396,920 | [['C23.888.592.612.054.200', 'C23.888.821.030.249'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['L01.313.500.750.300.188', 'L01.470.750'], ['Z01.542.816.124'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['A01.923.047.365'], ['C23.300.707'], ['E04.680.325'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Diseases [C]', 'Named Groups [M]', 'Information Science [L]', 'Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Posttraumatic stress symptoms among adults caring for orphaned children in HIV-endemic South Africa. | There is growing evidence that mental health is a significant issue among families affected by AIDS-related parental deaths. The current study examined posttraumatic stress symptoms and identified risk factors among adults caring for AIDS-orphaned and other-orphaned children in an HIV-endemic South African community. A... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Caregivers', 'Child', 'Child, Orphaned', 'Cross-Sectional Studies', 'Female', 'Humans', 'Life Change Events', 'Logistic Models', 'Male', 'Risk Factors', 'Socioeconomic Factors', 'South Africa', 'Stress Disorders, Post-Traumatic'] | 23,539,187 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.108'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.85... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Bacterioplanes sanyensis gen. nov., sp. nov., a PHB-accumulating bacterium isolated from a pool of Spirulina platensis cultivation. | A Gram-negative, poly-3-hydroxybutyrate-accumulating rod bacterium, strain GYP-2(T), was isolated from a pool of marine Spirulina platensis cultivation, Sanya, China. Growth was observed at 10-45 °C and pH 6-10 in the presence of 1-10 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequences indicated that t... | ['Bacterial Typing Techniques', 'Base Composition', 'China', 'Culture Media', 'DNA, Bacterial', 'Fatty Acids', 'Hydroxybutyrates', 'Oceanospirillaceae', 'Phosphatidylethanolamines', 'Phospholipids', 'Phylogeny', 'Polyesters', 'Quinones', 'RNA, Ribosomal, 16S', 'Seawater', 'Sequence Analysis, DNA', 'Spirulina'] | 25,038,945 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['Z01.252.474.164'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['D10.251'], ['D02.241.081.114.937', 'D02.241.511.429', 'D10.251.400.143.781'], ['B03.440.595', 'B03.660.250.540'], ['D10.570.755.375.760.400.840'], ['D10.570.755'], ['G05.697'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Effectiveness of two methods of obtaining feedback on mental health services provided to anonymous recipients. | OBJECTIVE: The authors examined alternative methods for obtaining feedback from people receiving anonymous mental health services via Project Liberty, an initiative that provided free counseling to residents of the New York City area after the 2001 attacks on the World Trade Center.METHODS: Counselors offered all Engli... | ['Adult', 'Community Mental Health Services', 'Consumer Behavior', 'Crisis Intervention', 'Feedback, Psychological', 'Female', 'Follow-Up Studies', 'Freedom', 'Humans', 'Interview, Psychological', 'Male', 'New York City', 'Program Evaluation', 'September 11 Terrorist Attacks', 'Stress Disorders, Post-Traumatic', 'Surve... | 16,968,765 | [['M01.060.116'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['F01.145.236'], ['F04.754.252'], ['F01.058.288', 'F04.754.308'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.880.604.473.380', 'N03.706.437.380'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Applying controlled non-uniform deformation for in vitro studies of cell mechanobiology. | Cells within connective tissues routinely experience a wide range of non-uniform mechanical loads that regulate many cell behaviors. In this study, we developed an experimental system to produce complex strain patterns for the study of strain magnitude, anisotropy, and gradient effects on cells in culture. A standard e... | ['Anisotropy', 'Cells, Cultured', 'Elastic Modulus', 'Equipment Design', 'Equipment Failure Analysis', 'Fibroblasts', 'Flow Cytometry', 'Hardness', 'Humans', 'Mechanotransduction, Cellular', 'Physical Stimulation', 'Stress, Mechanical'] | 20,169,395 | [['G01.590.040', 'G02.050'], ['A11.251'], ['G01.374.590.605'], ['E05.320'], ['E05.325.192'], ['A11.329.228'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['G01.374.647'], ['B01.050.150.900.649.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissociation of the functional relevance of different pre-stimulus oscillatory activity for memory formation. | The state of a neural assembly preceding an incoming stimulus modulates the processing of that subsequently presented stimuli. For human memory formation, the role of oscillatory brain activity within different frequency ranges has been discussed but a more functional relation could not be established. In the present E... | ['Adult', 'Brain', 'Brain Mapping', 'Brain-Computer Interfaces', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Memory', 'Photic Stimulation', 'User-Computer Interface'] | 26,484,828 | [['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E07.305.076'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['E05.723.729'], ['L01.224.900.910']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Quantification of breast density using dual-energy mammography with liquid phantom calibration. | Breast density is a widely recognized potential risk factor for breast cancer. However, accurate quantification of breast density is a challenging task in mammography. The current use of plastic breast-equivalent phantoms for calibration provides limited accuracy in dual-energy mammography due to the chemical compositi... | ['Adipose Tissue', 'Animals', 'Breast', 'Calibration', 'Cattle', 'Mammography', 'Phantoms, Imaging'] | 24,971,873 | [['A10.165.114'], ['B01.050'], ['A01.236'], ['E05.978.155'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.350.700.500'], ['E07.671']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bisphosphonate therapy and osteonecrosis of the jaw complicated with a temporal abscess in an elderly woman with rheumatoid arthritis: a case report. | Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of bisphosphonate therapy. Orally administered bisphosphonates, widely used for the treatment of osteoporosis, are rarely associ... | ['Abscess', 'Aged', 'Anti-Bacterial Agents', 'Arthritis, Rheumatoid', 'Bisphosphonate-Associated Osteonecrosis of the Jaw', 'Diagnosis, Differential', 'Female', 'Humans', 'Mandibular Diseases', 'Radiography, Panoramic', 'Tomography, X-Ray Computed'] | 25,187,700 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C05.116.852.087', 'C05.500.086', 'C07.320.086', 'C23.550.717.732.183'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.500.607', 'C07.320.61... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Study of the degree of sanitary culture among students (study including several colleges in the country)]. | Laboratory of healthy lifestyle formation among students conducted a survey, the object of the study being first-year students. The study was conducted in three higher educational institutions of pedagogical orientation in different regions of the country. Students' opinions and views were studied as well as their actu... | ['Adolescent', 'Adult', 'Georgia (Republic)', 'Health Education', 'Humans', 'Latvia', 'Life Style', 'Russia', 'Students', 'Surveys and Questionnaires', 'Teaching', 'Vocational Education'] | 2,150,718 | [['M01.060.057'], ['M01.060.116'], ['Z01.542.900.420', 'Z01.542.931.420', 'Z01.586.950.420'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.136.560'], ['F01.829.458'], ['Z01.252.122.500', 'Z01.542.248.775'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N0... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Diversification and conservation of the extraembryonic tissues in mediating nutrient uptake during amniote development. | The transfer of nutrients from the mother through the chorioallantoic placenta meets the nutritional needs of the embryo during human prenatal development. Although all amniotes start with a similar "tool kit" of extraembryonic tissues, an enormous diversity of extraembryonic tissue formation has evolved to accommodate... | ['Animals', 'Chorioallantoic Membrane', 'Embryonic Development', 'Extraembryonic Membranes', 'Female', 'Humans', 'Maternal-Fetal Exchange', 'Placenta', 'Pregnancy', 'Vertebrates'] | 23,050,970 | [['B01.050'], ['A10.615.284.375', 'A13.350.575', 'A16.331.400'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['A10.615.284', 'A16.254.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.455'], ['A16.710'], ['G08.686.784.769'], ['B01.050.150.900']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro antiparasitic activity of microbial pigments and their combination with phytosynthesized metal nanoparticles. | Bioactive pigments were extracted and purified from cultures of Serratia marcescens and Chromobacterium violaceum. Spectroscopic, FTIR, and HPLC analyses showed prodigiosin and violacein as the principle molecules in the extract. Bioactive microbial pigments prodigiosin, violacein and their combinations with phytosynth... | ['Anti-Bacterial Agents', 'Antimalarials', 'Chromobacterium', 'Drug Carriers', 'Gold', 'Humans', 'Indoles', 'Leukocytes, Mononuclear', 'Metal Nanoparticles', 'Pigments, Biological', 'Plants', 'Plasmodium falciparum', 'Prodigiosin', 'Serratia', 'Silver', 'Trypanocidal Agents', 'Trypanosoma brucei gambiense'] | 25,986,963 | [['D27.505.954.122.085'], ['D27.505.954.122.250.100.085'], ['B03.440.450.360', 'B03.660.075.525.100'], ['D26.255.260', 'E02.319.300.380'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Simultaneous determination of cefamandole and cefamandole nafate in human plasma and urine by high-performance liquid chromatography with column switching. | A high-performance liquid chromatographic method with column switching has been developed for the simultaneous determination of cefamandole and cefamandole nafate in plasma and urine. The plasma and urine samples were injected onto a precolumn packed with Corasil RP C18 (37-50 microns) after simple dilution with an int... | ['Cefamandole', 'Chromatography, High Pressure Liquid', 'Humans', 'Reproducibility of Results'] | 2,384,580 | [['D02.065.589.099.249.150', 'D02.886.665.074.150', 'D03.633.100.300.249.150'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Surgical and prosthodontic treatment of a patient with significant trauma to the middle and lower face secondary to a gunshot wound: a clinical report. | Large defects of dentofacial structures may result from trauma, disease (including neoplasms), and congenital anomalies. The location and size of the defects are related to difficulties that patients report relative to speech, mastication, swallowing, facial esthetics, and self-image. This article reports on the evalua... | ['Adolescent', 'Alveolar Ridge Augmentation', 'Bone Transplantation', 'Cephalometry', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Prosthesis, Implant-Supported', 'Denture Design', 'Denture, Overlay', 'Facial Bones', 'Facial Injuries', 'Fracture Fixation', 'Humans', 'Jaw, Edentulous, Partially', 'Male'... | 19,515,164 | [['M01.060.057'], ['E04.545.550.100', 'E06.645.550.100'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
HY5, Circadian Clock-Associated 1, and a cis-element, DET1 dark response element, mediate DET1 regulation of chlorophyll a/b-binding protein 2 expression. | DET1 is a pleiotropic regulator of Arabidopsis development and controls the expression of many light-regulated genes. To gain a better understanding of the mechanism by which DET1 controls transcription from light-regulated promoters, we identified elements in the chlorophyll a/b-binding protein 2 (CAB2) promoter that ... | ['Animals', 'Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Basic-Leucine Zipper Transcription Factors', 'Binding Sites', 'Circadian Rhythm', 'Coleoptera', 'Darkness', 'Gene Expression Regulation, Plant', 'Genes, Reporter', 'Intracellular Signaling Peptides and Proteins', 'Light', 'Luciferases', 'Molecular Seq... | 14,563,928 | [['B01.050'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260.108', 'D12.776.930.127'], ['G02.111.570.120'], ['G07.180.562.190'], ['B01.050.500.131.617.720.500.500.375'], ['G01.590.540.233'], ['G05.308.375'], ['G05.360.340.024.340.43... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Antibody-dependent cell-mediated cytotoxicity against cell lines generated by liver-specific idiotype-bearing antibody. | We produced a murine monoclonal antibody (mAb), designated H2-mAb, against a fractionated soluble phase of human liver homogenate which antibody reacted with human liver cells. A human antibody possessing the same idiotype as the H2-mAb, designated LSIA (liver-specific idiotype-bearing antibody), can be measured by a s... | ['Adult', 'Antibodies, Monoclonal', 'Antibody-Dependent Cell Cytotoxicity', 'Cell Line', 'Chronic Disease', 'Enzyme-Linked Immunosorbent Assay', 'Fluorescent Antibody Technique', 'Hepatitis', 'Humans', 'Isoantibodies', 'Sensitivity and Specificity'] | 7,773,351 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.287.070'], ['A11.251.210'], ['C23.550.291.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512.240', 'E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Accelerated arterial hypertension in a young male]. | Hypertensive crises are situations when arterial hypertension shows its immediate damaging potential, and in such circumstance, antihypertensive therapy provides its life-saving effectiveness. Among these situations are hypertensive emergencies, hypertensive urgencies, hypertensive encephalopathy, and also accelerated-... | ['Acute Kidney Injury', 'Adult', 'Anemia, Hemolytic', 'Antihypertensive Agents', 'Drug Therapy, Combination', 'Heart Failure', 'Hematuria', 'Humans', 'Hyperlipidemias', 'Hypertension, Malignant', 'Hyperuricemia', 'Male', 'Obesity', 'Papilledema', 'Recurrence', 'Renal Dialysis', 'Retinal Hemorrhage', 'Treatment Refusal'... | 15,219,076 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['C15.378.071.141'], ['D27.505.954.411.162'], ['E02.319.310'], ['C14.280.434'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500'], ['C14.907.489.330'], ['C23.550.44... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Association of Periodontitis with the Concentration Levels of Germanium and Tin in Hair. | The purpose of this study was to investigate whether or not the concentration levels of certain kinds of trace elements in hair are associated with periodontitis. We studied a total of 109 participants, which are composed of 25 participants with periodontitis and 84 participants without periodontitis. Periodontal condi... | ['Adult', 'Female', 'Germanium', 'Hair', 'Humans', 'Male', 'Mass Spectrometry', 'Middle Aged', 'Multivariate Analysis', 'Periodontitis', 'Tin'] | 29,525,849 | [['M01.060.116'], ['D01.268.513.750', 'D01.268.556.305', 'D01.552.544.305'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C07.465.714.533'], ['D01.268.556.875', 'D01.552.544.875']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Contribution of Bacteriophages to the Biology and Virulence of Pathogenic Clostridia. | Bacteriophages are key players in the evolution of most bacteria. Temperate phages have been associated with virulence of some of the deadliest pathogenic bacteria. Among the most notorious cases, the genes encoding the botulinum neurotoxin produced by Clostridium botulinum types C and D and the á-toxin (TcnA) produced... | ['Bacteriophages', 'Clostridioides difficile', 'Humans', 'Prophages', 'Virulence'] | 29,050,666 | [['B04.123'], ['B03.353.625.657.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.123.655'], ['G06.930']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuroimaging genetic analyses of novel candidate genes associated with reading and language. | Neuroimaging measures provide useful endophenotypes for tracing genetic effects on reading and language. A recent Genome-Wide Association Scan Meta-Analysis (GWASMA) of reading and language skills (N=1862) identified strongest associations with the genes CCDC136/FLNC and RBFOX2. Here, we follow up the top findings from... | ['Alternative Splicing', 'Brain Mapping', 'Chromosomes, Human', 'Female', 'Genome-Wide Association Study', 'Gray Matter', 'Humans', 'Male', 'Neoplasm Proteins', 'Polymorphism, Single Nucleotide', 'RNA Splicing Factors', 'Reading', 'Repressor Proteins'] | 27,476,042 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.8... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Diagnosis and treatment of infantile congenital subglottic hemangioma]. | OBJECTIVE: To discuss the diagnosis and treatment of infantile congenital subglottic hemangioma.METHOD: Nine patients with recurrent stridor, feeding difficulties and laryngeal obstruction were diagnosed as congenital subglottic hemangioma with bronchial endoscopy. The lesions were unilateral in 7 cases and bilateral i... | ['Antibiotics, Antineoplastic', 'Bleomycin', 'Female', 'Glottis', 'Hemangioma', 'Humans', 'Infant', 'Laryngeal Neoplasms', 'Male', 'Treatment Outcome'] | 19,947,255 | [['D27.505.954.248.106'], ['D09.400.420.110', 'D12.644.233.110'], ['A04.329.364'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
What do speech-language pathologists describe as most important when trying to achieve client participation during aphasia rehabilitation? A qualitative focus group interview study. | Purpose: The aim of this study was to investigate what speech-language pathologists describe as most important when trying to achieve client-oriented participation during aphasia rehabilitation. Method: A qualitative study including semi-structured focus group interviews with 11 speech-language pathologists. Interviews... | ['Aphasia', 'Attitude of Health Personnel', 'Clinical Decision-Making', 'Female', 'Focus Groups', 'Goals', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interviews as Topic', 'Language', 'Patient Participation', 'Patient-Centered Care', 'Professional-Patient Relations', 'Qualitative Research', 'Speech-Language Pa... | 29,252,012 | [['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['F01.100.050', 'N05.300.100'], ['E01.055'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.658.500'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Maternal serum angiopoietin-2 at 11 to 13 weeks of gestation in hypertensive disorders of pregnancy. | OBJECTIVE: In women with preeclampsia (PE), the serum concentration of the growth factor angiopoietin-2 (Ang-2) is significantly lower than in unaffected controls. The objective of this study is to determine if the decrease in serum Ang-2 is evident from the first trimester of pregnancy before the clinical onset of PE.... | ['Adult', 'Angiopoietin-2', 'Case-Control Studies', 'Female', 'Humans', 'Hypertension, Pregnancy-Induced', 'Mothers', 'Parity', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimester, First', 'Ultrasonography, Doppler', 'Ultrasonography, Prenatal'] | 19,499,513 | [['M01.060.116'], ['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.395', 'C14.907.489.480'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Balance between NF-êB p100 and p52 regulates T cell costimulation dependence. | c-IAP1 and c-IAP2 are ubiquitin protein ligases (E3s) that repress noncanonical NF-êB activation. We have created mice that bear a mutation in c-IAP2 that inactivates its E3 activity and interferes, in a dominant-negative fashion, with c-IAP1 E3 activity (c-IAP2(H570A)). The immune response of these animals was explore... | ['Animals', 'Enzyme Activation', 'I-kappa B Kinase', 'Immunologic Memory', 'Inhibitor of Apoptosis Proteins', 'Interferon-gamma', 'Interleukin-2', 'Lymphocyte Activation', 'Mice', 'Mice, Knockout', 'Mutation', 'NF-kappa B p52 Subunit', 'T-Lymphocytes', 'Toxoplasma', 'Toxoplasmosis'] | 23,248,260 | [['B01.050'], ['G02.111.263', 'G03.328'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['G12.450.050.500'], ['D08.811.464.938.750.210', 'D12.644.360.075.437', 'D12.776.476.075.437'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of LINE-1 methylation in predicting survival among colorectal cancer patients: a meta-analysis. | BACKGROUND: The prognostic value of long interspersed nucleotide element-1 (LINE-1) methylation in patients with colorectal cancer (CRC) remains uncertain. We have therefore performed a meta-analysis to elucidate this issue.METHODS: The PubMed and Web of Science databases were searched for studies published up to 30 Ju... | ['Colorectal Neoplasms', 'DNA Methylation', 'Disease-Free Survival', 'Humans', 'Long Interspersed Nucleotide Elements', 'Prognosis', 'Proportional Hazards Models'] | 28,343,299 | [['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modulation of suppressor mechanisms in allergic contact dermatitis: 2. Inhibition of suppressor T-lymphocytes by Corynebacterium parvum. | Pretreatment of BALB/c mice with Corynebacterium parvum inhibited the induction of tolerance to the contact sensitizing agent 2,4-dinitrofluorobenzene induced by intravenous injection of DNBSO3. The suppressive effect on tolerance induction has further been analyzed by adoptive transfer experiments. Injection of C. par... | ['Adjuvants, Immunologic', 'Animals', 'Dermatitis, Contact', 'Dinitrofluorobenzene', 'Dose-Response Relationship, Immunologic', 'Immune Tolerance', 'Mice', 'Propionibacterium acnes', 'T-Lymphocytes, Regulatory'] | 6,453,168 | [['D27.505.696.477.067'], ['B01.050'], ['C17.800.174.255', 'C17.800.815.255'], ['D02.455.426.559.389.565.280', 'D02.640.529.240.280'], ['G12.300'], ['G12.535.425'], ['B01.050.150.900.649.313.992.635.505.500'], ['B03.510.024.990.600.600', 'B03.510.460.400.400.600.600.600'], ['A11.118.637.555.567.550.500.700', 'A11.118.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The duodenal epithelium in duodenal diseases]. | The purpose of the study was to define duodenal epithelial function in duodenal diseases and to assess the potentialities of correction of detected dysfunctions. The electrical properties (EPs) of the duodenal epithelium were explored in patients with primary chronic duodenitis, duodenal peptic ulcer (DPU) on an exacer... | ['Chronic Disease', 'Duodenal Ulcer', 'Duodenitis', 'Duodenoscopy', 'Duodenum', 'Gastroscopy', 'Humans', 'Intestinal Mucosa'] | 15,656,395 | [['C23.550.291.500'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['C06.405.205.462.249', 'C06.405.469.275.600', 'C06.405.469.326.750'], ['E01.370.372.250.250.225', 'E01.370.388.250.250.250.200', 'E04.210.240.250.200', 'E04.502.250.250.250.200'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E01.370.372.250.250... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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