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Investigation of widespread neocortical pathology associated with hippocampal sclerosis in epilepsy: a postmortem study. | PURPOSE: One possible cause for surgical failure following temporal lobectomy for the treatment of epilepsy due to classical hippocampal sclerosis (CHS) is the presence of more widespread cortical changes. Neocortical changes in CHS shown by quantitative neuroimaging studies may involve hippocampal projection pathways.... | ['Adult', 'Aged', 'Epilepsy', 'Female', 'Hippocampus', 'Humans', 'Male', 'Middle Aged', 'Neocortex', 'Sclerosis'] | 21,198,557 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.490'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.420'], ['C23.550.823']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of age, location, and bicycle style on helmet usage by adults. | OBJECTIVE: Our objective was to describe current patterns of bicycle helmet usage in a university community using a direct observation approach.PARTICIPANTS: Cyclists in a university community observed in 2010 and 2011.METHODS: We identified 6 locations in Athens, Georgia, and recorded the type of bicycle, age group, s... | ['Adolescent', 'Adult', 'Age Factors', 'Analysis of Variance', 'Bicycling', 'Environment Design', 'Female', 'Georgia', 'Head Protective Devices', 'Humans', 'Male', 'Young Adult'] | 22,458,793 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['I03.450.642.845.140'], ['I01.283', 'I01.880.709.359', 'N06.230.145'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['E07.700.380', 'J01.637.708.560.750'], ['B01.050.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Retroviral vectors expressing soluble CD4: a potential gene therapy for AIDS. | Retroviral vectors have been developed which produce a secreted form of the helper/inducer T-cell antigen, CD4. Amphotropically packaged vectors were used to transduce cells, and these cells were shown to express the secreted CD4 (sCD4) gene product. The sCD4 produced by the viral vectors is immunoprecipitated by monoc... | ['Acquired Immunodeficiency Syndrome', 'Animals', 'Base Sequence', 'CD4 Antigens', 'Cell Line', 'Cloning, Molecular', 'Genetic Therapy', 'Genetic Vectors', 'HIV Envelope Protein gp120', 'HIV-1', 'Humans', 'Mice', 'Precipitin Tests', 'Solubility', 'Transduction, Genetic'] | 2,328,156 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lithium aspirinate hemihydrate. | The title compound {systematic name: catena-poly[lithium(I)-mu3-acetylsalicylato-hemi-mu2-aqua]}, {[Li(C9H7O4)] x 0.5 H2O}n, is the hemihydrate of the lithium salt of aspirin. The carboxylate groups and water molecules bridge between Li atoms to form a one-dimensional coordination chain composed of two distinct ring ty... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Aspirin', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Lithium Carbonate', 'Models, Molecular', 'Molecular Structure', 'Solubility', 'Water'] | 18,057,595 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389.657.410.595.176'], ['E05.196.309.742.225'], ['G02.282'], ['D01.045.125.500', 'D01.200.275.150.550', 'D01.510.475'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G02.805'], ['D01.045.250.875', 'D01.248.497.158.459... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison and analyses of therapeutic effects between metabolic management center (MMC) and conventional management modes. | AIMS: The past 3 decades witnessed the rapid growth of diabetes in China. To better serve large numbers of patients, the Chinese Medical Doctor Association launched metabolic management center (MMC) program which is featured with a one-stop and comprehensive diabetes management mode in 2016. It is worth exploring wheth... | ['China', 'Comprehensive Health Care', 'Diabetes Mellitus, Type 2', 'Female', 'Health Care Costs', 'Humans', 'Male', 'Middle Aged', 'Patient Education as Topic', 'Patient Satisfaction', 'Program Evaluation', 'Self-Management', 'Standard of Care', 'Surveys and Questionnaires'] | 32,248,347 | [['Z01.252.474.164'], ['N04.590.233'], ['C18.452.394.750.149', 'C19.246.300'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N... | ['Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Rab7 mutants associated with Charcot-Marie-Tooth disease cause delayed growth factor receptor transport and altered endosomal and nuclear signaling. | Rab7 belongs to the Ras superfamily of small GTPases and is a master regulator of early to late endocytic membrane transport. Four missense mutations in the late endosomal Rab7 GTPase (L129F, K157N, N161T, and V162M) cause the autosomal dominant peripheral neuropathy Charcot-Marie-Tooth type 2B (CMT2B) disease. As yet,... | ['Animals', 'Cell Line', 'Cell Nucleus', 'Charcot-Marie-Tooth Disease', 'Endosomes', 'ErbB Receptors', 'Genes, fos', 'Humans', 'Laminopathies', 'MAP Kinase Signaling System', 'Microscopy, Fluorescence', 'Mutagenesis', 'Mutation, Missense', 'Protein Transport', 'Reverse Transcriptase Polymerase Chain Reaction', 'Signal ... | 23,188,822 | [['B01.050'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['A11.284.430.214.190.875.190.880.337'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical treatment of Wolff-Parkinson-White syndrome: analysis of the methods and results]. | The authors analyse the outcomes of surgical management in 400 patients with the Wolff-Parkinson-White syndrome who had been operated on in the All-Union Centre for Surgical treatment of Severe Cardiac Arrhythmias and Electrocardiostimulation. Unique surgical procedures were applied, which made it possible to perform c... | ['Adult', 'Aged', 'Atrioventricular Node', 'Child', 'Contraindications', 'Cryosurgery', 'Extracorporeal Circulation', 'Humans', 'Intraoperative Care', 'Middle Aged', 'Wolff-Parkinson-White Syndrome'] | 2,087,028 | [['M01.060.116'], ['M01.060.116.100'], ['A07.541.409.147'], ['M01.060.406'], ['E02.208'], ['E04.014.180'], ['E04.292'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['M01.060.116.630'], ['C14.280.067.780.977', 'C14.280.123.750.977', 'C16.131.240.400.980']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lymphoproliferative disease presenting as obstructive uropathy after renal transplantation. | Lymphoproliferative disorders occur with a greater frequency in recipients of solid organ transplants. Unlike in the general population, these tumors tend to arise in extranodal sites and are often confined to a single organ. We report on a patient with lymphoproliferative disease confined to the hilum of the renal all... | ['Humans', 'Kidney Neoplasms', 'Kidney Transplantation', 'Lymphoma, B-Cell', 'Male', 'Middle Aged', 'Ureteral Obstruction'] | 7,815,594 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C04.557.386.480.150', 'C15.604.515.569.480.150', 'C20.683.515.761.480.150'], ['M01.060.116.630'], ['C12.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence of precipitating antibodies against mycoplasmas and viruses in egg-laying flocks in Northern Jutland. | Antibodies against infectious laryngotracheitis virus, influenavirus and Newcastle disease virus were not demonstrated. The prevalence of infections caused by adeno- and reovirus in egg-laying flocks was 85 and 74% respectively. Approximately 25% of the flocks had antibodies against infectious bronchitis virus and infe... | ['Animals', 'Antibodies, Bacterial', 'Antibodies, Viral', 'Chickens', 'Denmark', 'Female', 'Mycoplasma Infections', 'Poultry Diseases', 'Precipitin Tests', 'Virus Diseases'] | 643,540 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['Z01.542.816.124'], ['C01.150.252.400.610.610'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Isolation of pathogenic bacteria from induced sputum from hospitalized children with pneumonia in Bangladesh. | A prospective study was carried out on 157 patients admitted to a paediatric hospital in Dhaka, Bangladesh to determine the bacteria present in the induced sputum of paediatric patients with X-ray proven pneumonia. Their ages ranged from 21 days to 11 years; 65 per cent of them were male and 35 per cent were female. Th... | ['Age Distribution', 'Anti-Bacterial Agents', 'Bangladesh', 'Bronchial Provocation Tests', 'Child', 'Child, Preschool', 'Female', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacterial Infections', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Microbial Sensitivity Tests', 'Pharynx', 'Pneumonia, ... | 9,972,076 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['D27.505.954.122.085'], ['Z01.252.245.131'], ['E01.370.386.700.125'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.400'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Internal spermatic vein diameter and age at operation reflect the response to varicocelectomy. | It was evaluated whether the diameter of internal spermatic veins (measured directly during operation) correlates with the clinical grade and treatment outcome following varicocelectomy. Fifty-seven consecutive men undergoing left varicocelectomy were included in the study, and spermatic vein diameter was compared with... | ['Adult', 'Aged', 'Aging', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Sperm Count', 'Sperm Motility', 'Spermatic Cord', 'Treatment Outcome', 'Varicocele'] | 11,736,796 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['E01.370.225.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chemical constituents of Narcissus tazetta var. chinensis and their antioxidant activities. | Two new flavan derivatives tazettones C-D (1-2), one new â-coumaranone (tazettone E, 3), one new flavan (tazettone F, 4), and one new phenylpropanoid (tazettone G, 5), together with six known flavonoids (6-11), were isolated from the bulbs of Narcissus tazetta var. chinensis Roem. Their structures were elucidated by sp... | ['Antioxidants', 'Cell Line, Tumor', 'Flavanones', 'Humans', 'Hydrogen Peroxide', 'Molecular Structure', 'Narcissus', 'Plant Roots'] | 27,476,617 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of peripheral blood mononuclear cell prematurely condensed chromosomes for biological dosimetry. | Even though the premature chromosome condensation (PCC) technique has been shown to be a powerful cytogenetic tool, it has not yet been applied for biological dosimetry purposes. An improved and simple methodology for polyethylene glycol-mediated cell fusion and PCC induction has given the opportunity to explore the us... | ['Animals', 'Cell Line', 'Chromosome Aberrations', 'Cricetinae', 'Cricetulus', 'Female', 'Hybrid Cells', 'Monocytes', 'Ovary', 'Radiation Dosage'] | 6,539,927 | [['B01.050'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['A11.251.600'], ['A11.118.637.555.652', 'A11.148.580', 'A11.627.624', 'A11.733.547', 'A15.145.229.637.555.652', 'A15.378.316.580', 'A15.382.490.555.652', 'A15... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The acid tolerance response of Salmonella typhimurium involves transient synthesis of key acid shock proteins. | Although Salmonella typhimurium prefers neutral-pH environments, it can adapt to survive conditions of severe low-pH stress (pH 3.3). The process, termed the acid tolerance response (ATR), includes two distinct stages. The first stage, called pre-acid shock, is induced at pH 5.8 and involves the production of an induci... | ['Acids', 'Adaptation, Physiological', 'Bacterial Proteins', 'Drug Resistance', 'Homeostasis', 'Hydrogen-Ion Concentration', 'Iron', 'Repressor Proteins', 'Salmonella typhimurium', 'Time Factors'] | 8,458,840 | [['D01.029'], ['G07.025', 'G16.012.500'], ['D12.776.097'], ['G07.690.773.984'], ['G07.410'], ['G02.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D12.776.260.703', 'D12.776.930.780'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequency specific patterns of resting-state networks development from childhood to adolescence: A magnetoencephalography study. | OBJECTIVE: The present study investigated frequency dependent developmental patterns of the brain resting-state networks from childhood to adolescence.METHOD: Magnetoencephalography (MEG) data were recorded from 20 healthy subjects at resting-state with eyes-open. The resting-state networks (RSNs) was analyzed at sourc... | ['Adolescent', 'Alpha Rhythm', 'Beta Rhythm', 'Brain', 'Brain Mapping', 'Child', 'Child Development', 'Female', 'Humans', 'Magnetoencephalography', 'Male', 'Neural Pathways', 'Rest'] | 27,287,665 | [['M01.060.057'], ['E01.370.376.300.150.374', 'E01.370.405.245.287.374', 'G07.265.087.500', 'G11.561.127.500'], ['E01.370.376.300.150.750', 'E01.370.405.245.287.750', 'G07.265.087.750', 'G11.561.127.750'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['M01.060.406'], ['F01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Burns in children with special reference to the benefits of primary excision and immediate grafting. | This report gives an analysis of average types of burns seen in children in Finland. The majority were small infants under two years of age who had sustained the burns indoors from scalding with hot water. Cold water immersion was given in half of the cases as first aid treatment. Most of the cases were of a minor degr... | ['Adolescent', 'Age Factors', 'Burns', 'Child', 'Child, Preschool', 'Fluid Therapy', 'Humans', 'Infant', 'Length of Stay', 'Skin Transplantation', 'Transplantation, Autologous'] | 7,008,683 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C26.200'], ['M01.060.406'], ['M01.060.406.448'], ['E02.319.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['E04.936.664']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Invasive nematode larvae of the order Spirurida from pasture flies]. | A key for the identification of infective larvae is presented which has proved useful for epizootiological studies. | ['Animals', 'Diptera', 'Insect Vectors', 'Larva', 'Spiruroidea', 'USSR'] | 2,616,198 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.500.500.294.400.937.700.680'], ['Z01.542.931', 'Z01.586.950']] | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Assessment of commercial test kits for identification of spring viraemia of carp virus. | Two test kits for the identification of spring viraemia of carp virus (SVCV), one an enzyme-linked immunosorbent assay (ELISA) using a rabbit polyclonal antiserum, and the other an indirect fluorescent antibody test (IFAT) using a mouse monoclonal antibody, were assessed for specificity using a range of virus isolates.... | ['Animals', 'Carps', 'Enzyme-Linked Immunosorbent Assay', 'Fish Diseases', 'Fluorescent Antibody Technique, Indirect', 'Rhabdoviridae Infections', 'Species Specificity', 'Vesiculovirus'] | 16,385,804 | [['B01.050'], ['B01.050.150.900.493.200.244.248'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C22.362'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. | AIM: This paper reviews the proceedings and conclusions of a meeting of experts concerned with the problem of hypomineralised incisors and molars (MIH). The aims of this meeting were to establish criteria for the judgement of MIH, to select representative cases and to discuss how the name of the condition was best desc... | ['Child', 'Dental Enamel Hypoplasia', 'Diagnosis, Differential', 'Humans', 'Incisor', 'Molar', 'Terminology as Topic', 'Tooth Calcification'] | 14,529,329 | [['M01.060.406'], ['C07.650.800.255', 'C07.793.700.255', 'C16.131.850.800.255'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860.425'], ['A14.549.167.860.525'], ['L01.559.598.400'], ['G07.345.155.500.710', 'G10.549.800']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Salmonella Typhimurium outbreak associated with smoked pork tenderloin in Denmark, January to March 2011. | BACKGROUND: An outbreak of salmonellosis (Salmonella Typhimurium, phage type DT120) occurred from 26 January to 15 March 2011, in Denmark, with 22 laboratory confirmed cases. Hypothesis-generating patient interviews gave rise to the suspicion that smoked pork tenderloin was the source of infection. The primary objectiv... | ['Bacteriophage Typing', 'Case-Control Studies', 'Denmark', 'Disease Outbreaks', 'Feces', 'Foodborne Diseases', 'Humans', 'Minisatellite Repeats', 'Molecular Typing', 'Salmonella Infections', 'Salmonella typhimurium'] | 22,804,453 | [['E01.370.225.875.150.125.150', 'E05.200.875.150.125.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.542.816.124'], ['N06.850.290'], ['A12.459'], ['C25.723.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.708.800.550', 'G05.360.080.708.800.550', 'G05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A new species of the genus Oxyporus Fabricius (Coleoptera: Staphylinidae: Oxyporinae) in Yunnan Province, China. | A new species of the genus Oxyporus Fabricius, 1775 is described based on specimens collected in Yunnan Province, China, namely Oxyporus (Oxyporus) tuantianius sp. nov. from Xinping County. The number of Oxyporus species worldwide is thus increased to 131. Color images of the habitus and aedeagus of the new species are... | ['Animals', 'China', 'Coleoptera'] | 30,790,825 | [['B01.050'], ['Z01.252.474.164'], ['B01.050.500.131.617.720.500.500.375']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Fetal bone marrow CD34+CD41+ cells are enriched for multipotent hematopoietic progenitors, but not for pluripotent stem cells. | We have investigated the expression of CD41a (gpIIbIIIa) on a subpopulation of human fetal bone marrow (FBM) CD34+ progenitor cells. Human FBM CD34+Lin- cells were subfractionated into CD41a+ and CD41a- subpopulations by flow cytometry. All the megakaryocyte colony-forming cells (CFU-MK) and almost all the burst-formin... | ['Antigens, CD34', 'Bone Marrow', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Lineage', 'Cell Separation', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Flow Cytometry', 'Hematopoietic Stem Cells', 'Humans', 'Immunophenotyping', 'Megakaryocytes', 'Platelet Glycoprotein GPIIb-IIIa Complex', 'Stem Cells', 'Thr... | 8,641,347 | [['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of lentivirus-mediated CREB expression in the dorsolateral striatum: memory enhancement and evidence for competitive and cooperative interactions with the hippocampus. | Neural systems specialized for memory may interact during memory formation or recall, and the results of interactions are important determinants of how systems control behavioral output. In two experiments, we used lentivirus-mediated expression of the transcription factor CREB (LV-CREB) to test if localized manipulati... | ['Animals', 'Conditioning, Psychological', 'Corpus Striatum', 'Cyclic AMP Response Element-Binding Protein', 'Fear', 'Gene Expression', 'Genetic Vectors', 'Hippocampus', 'Learning', 'Lentivirus', 'Male', 'Maze Learning', 'Memory', 'Rats', 'Rats, Long-Evans', 'Rats, Transgenic', 'Recombinant Proteins', 'Systems Biology'... | 23,939,934 | [['B01.050'], ['F02.463.425.179'], ['A08.186.211.200.885.287.249.487'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['F01.470.361'], ['G05.297'], ['G05.360.337'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['F02.463.425', 'F02.784.629.529'], ['B04.820.650.589'], ['F02.463.425.874.500'], ['F02.463.4... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
N-terminal B-type natriuretic peptide urinary concentrations and retinopathy of prematurity. | BackgroundTo validate the findings of a single-center pilot study showing elevated urinary N-terminal B-type natriuretic peptide (NTproBNP) concentrations in preterm infants subsequently developing severe retinopathy of prematurity (ROP) in a multicenter setting across eight European and Middle East countries.MethodsPr... | ['Female', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Natriuretic Peptide, Brain', 'Pilot Projects', 'Prospective Studies', 'Retinopathy of Prematurity', 'Survival Analysis'] | 28,738,027 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776.631.590'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450... | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Determine the structure of phosphorylated modification of icariin and its antiviral activity against duck hepatitis virus A. | BACKGROUND: Our previous research showed that icariin (1) and its phosphorylated structural modification (2) improved the survival and attenuated oxidative stress and liver dysfunction induced by duck virus hepatitis. In this paper, we were one step closer to determine the structure of phosphorylation icariin (2) by th... | ['Animals', 'Antiviral Agents', 'Ducks', 'Flavonoids', 'Hepatitis Virus, Duck', 'Hepatitis, Viral, Animal', 'Molecular Structure', 'Phosphorylation', 'Poultry Diseases', 'Virus Replication'] | 26,272,639 | [['B01.050'], ['D27.505.954.122.388'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B04.450.416', 'B04.820.578.750.284.645'], ['C01.436.430', 'C01.925.407', 'C06.552.380.315.430', 'C22.467.435'], ['G02.111.570', 'G02.466'], ['G02.111.665', 'G0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HU-211, a non-psychotropic cannabinoid, rescues cortical neurones from excitatory amino acid toxicity in culture. | The present study examined potential neuroprotective effects of HU-211, a synthetic non-psychotropic cannabinoid with non-competitive NMDA antagonist properties on neurones exposed to various excitotoxins in culture. HU-211 was found to protect neurones from NMDA and quisqualate-induced toxicity but not that produced b... | ['Amino Acids', 'Animals', 'Cannabinoids', 'Cell Survival', 'Cells, Cultured', 'Cerebral Cortex', 'Dizocilpine Maleate', 'Dronabinol', 'Immunohistochemistry', 'Membranes', 'Neurons', 'Phosphopyruvate Hydratase', 'Radioligand Assay', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate'] | 8,298,080 | [['D12.125'], ['B01.050'], ['D02.455.849.090'], ['G04.346'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['D02.455.849.090.810'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting protein. | Tail-interacting 47-kDa protein (TIP47) binds the cytoplasmic domains of the cation-dependent (CD) and cation-independent (CI) mannose 6-phosphate receptors (MPRs) and is required for their transport from endosomes to the Golgi complex. TIP47 recognizes a phenylalanine-tryptophan signal in the CD-MPR. We show here that... | ['Amino Acid Sequence', 'Binding Sites', 'Cytoplasm', 'DNA-Binding Proteins', 'Intracellular Signaling Peptides and Proteins', 'Perilipin-3', 'Pregnancy Proteins', 'Protein Binding', 'Receptor, IGF Type 2', 'Recombinant Fusion Proteins', 'Vesicular Transport Proteins'] | 10,908,666 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['A11.284.430.214'], ['D12.776.260'], ['D12.644.360', 'D12.776.476'], ['D12.776.157.464.500.875'], ['D12.776.780'], ['G02.111.679', 'G03.808'], ['D12.776.543.750.750.400.780.410'], ['D12.776.828.300'], ['D12.776.543.990']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
miR-2703 regulates the chitin biosynthesis pathway by targeting chitin synthase 1a in Nilaparvata lugens. | The chitin biosynthesis pathway is an important physiology process in arthropods. However, few microRNAs (miRNAs) involved in the regulation of the chitin biosynthesis pathway in insects have been reported until now. In this study, four groups of samples that either upregulated or downregulated the chitin biosynthesis ... | ['Animals', 'Chitin', 'Chitin Synthase', 'Ecdysterone', 'Hemiptera', 'Insect Proteins', 'MicroRNAs', 'Molting', 'Nymph', 'RNA Interference', 'RNA, Double-Stranded', 'Transcription Factors'] | 31,260,146 | [['B01.050'], ['D05.750.078.139', 'D09.698.211'], ['D08.811.913.400.450.460.200'], ['D04.210.500.247.222.265.165.750', 'D06.472.445.573.271.750'], ['B01.050.500.131.617.412'], ['D12.776.093.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G07.345.500.550.750'], ['B05.500.650', 'G07.345.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of metal-free sulfonated phthalocyanine in subcutaneously transplanted murine tumors. | Metal-free sulfonated phthalocyanine with the average number of sulfonate groups per molecule 2.4 (H(2)PcS(2.4)) was recently proved to be an efficient photosensitizer for the photodynamic therapy. Fluorescence spectral imaging microscopy was applied here to study localization and relative concentration of H(2)PcS(2.4)... | ['Animals', 'Breast Neoplasms', 'Carcinoma, Lewis Lung', 'Female', 'Indoles', 'Injections, Intravenous', 'Leukemia, Lymphoid', 'Melanoma, Experimental', 'Metals', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Photochemotherapy', 'Photosensitizing Agents', 'Tissue Distribution'] | 15,246,354 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.280', 'C04.619.230'], ['D03.633.100.473'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['C04.557.337.428', 'C15.604.515.560', 'C20.683.515.528'], ['C04.557.465.625.650.510.525', 'C04.557.580.625.650.510.525', 'C04.557.665.510.525', 'C04.619.600', '... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-dose daclizumab for the treatment of juvenile idiopathic arthritis-associated active anterior uveitis. | PURPOSE: To provide preliminary data regarding the safety and efficacy of high-dose intravenous daclizumab (Zenapax; Roche Inc, Nutley, New Jersey, USA) therapy for the treatment of juvenile idiopathic arthritis (JIA)-associated active anterior uveitis.DESIGN: Interventional case series; open-label prospective, phase I... | ['Adolescent', 'Anterior Chamber', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Arthritis, Juvenile', 'Child', 'Daclizumab', 'Female', 'Humans', 'Immunoglobulin G', 'Immunosuppressive Agents', 'Infusions, Intravenous', 'Male', 'Pilot Projects', 'Prospective Studies', 'Treatment Outcome', 'Uveitis, An... | 19,664,754 | [['M01.060.057'], ['A09.371.060.067'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.060... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Strabismus in Cameroon]. | PURPOSE: We undertook a study on strabismus in order to determine the characteristics of this disease in Cameroon.MATERIAL AND METHODS: A prospective study was carried out in the ophthalmological unit of the Douala General Hospital from November 1991 to October 1995. All patients were examined and followed regularly by... | ['Adolescent', 'Amblyopia', 'Cameroon', 'Child', 'Child, Preschool', 'Esotropia', 'Exotropia', 'Female', 'Humans', 'Infant', 'Male', 'Nystagmus, Pathologic', 'Prospective Studies', 'Strabismus'] | 9,033,892 | [['M01.060.057'], ['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['Z01.058.290.100.110'], ['M01.060.406'], ['M01.060.406.448'], ['C10.292.562.887.300', 'C11.590.810.400'], ['C10.292.562.887.650', 'C11.590.810.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'],... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Inter- and intraobserver reproducibility in radiographic diagnosis and classification of femoral trochlear dysplasia. | Dejour's radiographic criteria are commonly used to diagnose and assess femoral trochlear dysplasia in case of patello-femoral instability. The aim of this study was to establish the intra- and interobserver reliability of these radiographic criteria. Sixty-eight lateral knee radiographs were examined independently by ... | ['Adult', 'Female', 'Femur', 'Humans', 'Joint Dislocations', 'Joint Instability', 'Knee Joint', 'Male', 'Observer Variation', 'Patella', 'Radiography'] | 9,787,397 | [['M01.060.116'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['C05.550.521'], ['A02.835.583.475'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['A02.835.232.043.650.624', 'A02.835.232.730.500'], ['E01.370.350.700']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A new acidophilic thermostable endo-1,4-â-mannanase from Penicillium oxalicum GZ-2: cloning, characterization and functional expression in Pichia pastoris. | BACKGROUND: Endo-1,4-â-mannanase is an enzyme that can catalyze the random hydrolysis of â-1, 4-mannosidic linkages in the main chain of mannans, glucomannans and galactomannans and has a number of applications in different biotechnology industries. Penicillium oxalicum is a powerful hemicellulase-producing fungus (Bio... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Enzyme Stability', 'Fungal Proteins', 'Galactans', 'Kinetics', 'Mannans', 'Molecular Sequence Data', 'Penicillium', 'Phylogeny', 'Pichia', 'Plant Gums', 'Sequence Alignment', 'Substrate Specificity', 'beta-Mannosidase'] | 25,348,022 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['E05.916.360', 'G02.111.700.500'], ['D12.776.354'], ['D09.698.360'], ['G01.374.661', 'G02.111.490'], ['D09.698.550'], ['L01.453.245.667'], ['B01.300.381.662'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.300.107.795.700', 'B01.300.930.600'], ['D05.750.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cycling Versus Continuous Mode In Neuromodulator Programming: A Crossover, Randomized, Controlled Trial. | This is a randomized, controlled, blind, crossover trial comparing cycling versus continuous programming of a sacral neuromodulator in women diagnosed with overactive bladder (OAB). At 6 months, treatment order significantly affected Overactive Bladder Questionnaire - Short Form (OABq-SF) symptom scores. The cycling fo... | ['Aged', 'Aged, 80 and over', 'Cross-Over Studies', 'Double-Blind Method', 'Electric Stimulation Therapy', 'Female', 'Humans', 'Lumbosacral Plexus', 'Middle Aged', 'Surveys and Questionnaires', 'Treatment Outcome', 'Urinary Bladder, Overactive'] | 27,501,593 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.450'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Utility of Combining Whole Genome Sequencing with Traditional Investigational Methods To Solve Foodborne Outbreaks of Salmonella Infections Associated with Chicken: A New Tool for Tackling This Challenging Food Vehicle. | High consumption rates and a multitude of brands make multistate foodborne outbreaks of Salmonella infections associated with chicken challenging to investigate, but whole genome sequencing is a powerful tool that can be used to assist investigators. Whole genome sequencing of pathogens isolated from clinical, environm... | ['Animals', 'Chickens', 'Disease Outbreaks', 'Food Microbiology', 'Humans', 'Polymorphism, Single Nucleotide', 'Salmonella Infections'] | 28,294,686 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['N06.850.290'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.598'], ['C01.150.252.400.310.... | ['Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Peripheral Nerve Ultrasound Imaging Shows Enlargement of Peripheral Nerves Outside the Brachial Plexus in Neuralgic Amyotrophy. | PURPOSE: Neuralgic amyotrophy is characterized by acute or subacute onset of shoulder and arm pain, followed by muscle atrophy and weakness, and variable sensory abnormalities. Historically, the site of inflammation has been localized to the brachial plexus, although the involvement of individual nerve branches has bee... | ['Adult', 'Brachial Plexus Neuritis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peripheral Nerves', 'Ultrasonography'] | 27,749,462 | [['M01.060.116'], ['C10.668.829.100.500', 'C10.668.829.650.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.800.800'], ['E01.370.350.850']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
GATA DNA-binding protein expressed in mouse I-10 Leydig testicular tumor cells. | A nuclear extract of the mouse I-10 Leydig tumor cell line was analyzed by gel mobility shift assay with a combination of antibodies for various mammalian GATA proteins. Antibodies for GATA-4 caused a super-shift of the DNA-protein complex, which is formed through GATA-4 binding to an oligonucleotide with a typical GAT... | ['Animals', 'Base Sequence', 'Binding Sites', 'Bucladesine', 'DNA Primers', 'DNA, Neoplasm', 'DNA-Binding Proteins', 'GATA4 Transcription Factor', 'Gene Expression', 'Leydig Cell Tumor', 'Leydig Cells', 'Male', 'Mice', 'Neoplasm Proteins', 'Testicular Neoplasms', 'Transcription Factors', 'Tumor Cells, Cultured', 'Zinc ... | 11,327,717 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.425'], ['D12.776.260'], ['D12.776.260.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of menstrual cycle on metabolic responses to exercise. | Selected substrate and hormonal responses to exercise were compared in two phases of the menstrual cycle. Exercise-induced changes in substrate [glucose, lactate, free fatty acids (FFA), glycerol] and hormonal patterns [luteinizing hormone (LH), follicle-stimulating hormone (FSH), insulin, progesterone (P), growth horm... | ['Adult', 'Blood Glucose', 'Endocrine Glands', 'Fatty Acids, Nonesterified', 'Female', 'Follicle Stimulating Hormone', 'Glycerol', 'Growth Hormone', 'Humans', 'Hydrocortisone', 'Insulin', 'Lactates', 'Luteinizing Hormone', 'Menstruation', 'Metabolism', 'Physical Exertion', 'Progesterone'] | 6,417,083 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['A06.300'], ['D10.251.310'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40). | BACKGROUND: SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been implicated in the control of wound healing. Here we examined the function of SPARC in cutaneous wound healing using SPARC-null mice and dermal fibroblasts de... | ['Animals', 'Cells, Cultured', 'Collagen', 'Extracellular Matrix Proteins', 'Fibroblasts', 'Fibronectins', 'Granulation Tissue', 'Kinetics', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Osteonectin', 'RNA, Messenger', 'Skin', 'Skin Physiological Phenomena', 'Wound Healing'] | 11,532,190 | [['B01.050'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.776.860.300'], ['A11.329.228'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['A10.165.450'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.5... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cerebrospinal fluid leak following acoustic neuroma removal. | Cerebrospinal fluid (CSF) leak has been a constant and unresolved complication of acoustic tumor surgery. This study retrospectively reviews 381 primary acoustic tumor surgeries performed by a single, senior, neurotologist and neurosurgeon team from 1979 through 1991. There were 68 cerebrospinal fluid leaks in 66 patie... | ['Cerebrospinal Fluid Rhinorrhea', 'Cohort Studies', 'Drainage', 'Female', 'Fibrin Tissue Adhesive', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Neuroma, Acoustic', 'Postoperative Complications', 'Retrospective Studies', 'Suture Techniques'] | 8,295,455 | [['C10.597.114.750', 'C10.900.300.109.750', 'C23.888.592.114.624', 'C23.888.852.834.500', 'C26.915.300.225.750'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.309', 'E04.237'], ['D12.776.124.270.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', '... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival. | Cells from Bloom's syndrome patients display genome instability due to a defective BLM and the downregulation of cytidine deaminase. Here, we use a genome-wide RNAi-synthetic lethal screen and transcriptomic profiling to identify genes enabling BLM-deficient and/or cytidine deaminase-deficient cells to tolerate constit... | ['Bloom Syndrome', 'Cell Survival', 'Cytidine Deaminase', 'DNA, Ribosomal', 'Down-Regulation', 'Genomic Instability', 'HeLa Cells', 'Humans', 'RecQ Helicases', 'Up-Regulation', 'tau Proteins'] | 28,947,735 | [['C16.131.077.137', 'C16.320.798.313', 'C18.452.284.100', 'C20.673.795.313'], ['G04.346'], ['D08.811.277.151.486.250'], ['D13.444.308.475'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical and hemodynamic effects of combined propranolol and nifedipine therapy versus propranolol alone in patients with angina pectoris. | To determine the comparative effectiveness and hemodynamic effects of long-term oral treatment with propranolol alone and combined with nifedipine in patients with stable angina pectoris, 20 patients with coronary disease were studied by equilibrium radionuclide ventriculography. Measurements were performed at rest and... | ['Administration, Oral', 'Adult', 'Aged', 'Angina Pectoris', 'Blood Pressure', 'Drug Therapy, Combination', 'Heart Rate', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Nifedipine', 'Propranolol', 'Stroke Volume'] | 3,976,473 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E02.319.310'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[New photoreactive N(4)-substituted dCTP analogues:synthesis, photochemical characteristics, and substrate properties in HIV-1 reverse transcriptase catalyzed DNA synthesis]. | Photochemical characteristics and substrate properties of four newly synthesized dCTP analogues: N4-[2-(2-nitro-5-azidobenzoylamino)ethyl]-, N4-[2-(4-azidotetrafluorobenzylideneaminooxymethylcarbamoyl)ethyl] -, N4-[4-(4-azidotetrafluorobenzylideneaminooxy)butyloxy]-, and N4-[4-(4-azidotetrafluorobenzylidene hydrazinoca... | ['Catalysis', 'DNA', 'DNA Primers', 'Deoxycytosine Nucleotides', 'HIV Reverse Transcriptase', 'Photochemistry', 'Structure-Activity Relationship', 'Substrate Specificity', 'Ultraviolet Rays'] | 9,471,978 | [['G02.130'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D03.383.742.686.246.425', 'D13.695.201.150', 'D13.695.740.246.425'], ['D08.811.913.696.445.308.300.750.187', 'D12.776.964.775.375.545.875', 'D12.776.964.775.375.750.187', 'D12.776.964.775.562.764.875', 'D12.776.964.900.750.500.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationship of response to transurethral hyperthermia and prostate volume in BPH patients. | A response to transurethral microwave hyperthermia (TUHT) at 915 MHz and its relationship to prostate volume was examined in 63 poor surgical risk benign prostatic hyperplasia (BPH) patients. All patients had moderate-to-severe obstructive signs and symptoms, and received > or = 5 TUHT one-hour sessions. Treatment temp... | ['Aged', 'Follow-Up Studies', 'Humans', 'Hyperthermia, Induced', 'Male', 'Prostate', 'Prostatic Hyperplasia', 'Time Factors', 'Treatment Outcome'] | 1,384,220 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['A05.360.444.575', 'A10.336.707'], ['C12.294.565.500'], ['G01.910.857'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tryptophan levels in human cerebrospinal fluid after acute and chronic ethanol consumption. | The essential amino acid tryptophan was measured in human cerebrospinal fluid by a fluorometric high-performance liquid chromatographic method. Acute ethanol consumption (80 g) by healthy volunteers lead to a decrease in tryptophan levels during intoxication. After intoxication no difference from base levels was eviden... | ['Adolescent', 'Adult', 'Aged', 'Alcoholism', 'Brain', 'Chromatography, High Pressure Liquid', 'Ethanol', 'Humans', 'Male', 'Middle Aged', 'Serotonin', 'Tryptophan'] | 6,653,393 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C25.775.100.250', 'F03.900.100.350'], ['A08.186.211'], ['E05.196.181.400.300'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650'], ['D12.125.072.050.85... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Diagnosis of epidemic gastroenteritis]. | Epidemic gastroenteritis is a rather widespread disease, though as yet little known to medical practitioners. Its diagnosis is base on the correct evaluation of the complex of characteristics, both clinical and epidemiological; clinical characteristics include typical gastroenteritis with normal or subfebrile temperatu... | ['Acute Disease', 'Adolescent', 'Adult', 'Age Factors', 'Aged', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Gastroenteritis', 'Humans', 'Infant', 'Infant, Newborn', 'Middle Aged'] | 7,234,242 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['C06.405.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.630']] | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Screening for induction of differentiation and toxicity to blast cells by chemotherapeutic compounds in human myeloid leukemia. | Bone marrow cells from 9 patients with acute myeloid leukemia and 1 patient with a blast crisis of chronic myeloid leukemia were cultured to determine their ability to be induced to differentiate by different chemotherapeutic compounds. Five of these 10 patients showed differentiation to granulocytic and/or monocytic c... | ['Antineoplastic Agents', 'Bone Marrow', 'Cell Differentiation', 'Cells, Cultured', 'Dactinomycin', 'Drug Evaluation, Preclinical', 'Humans', 'Leukemia, Myeloid', 'Leukemia, Myeloid, Acute', 'Time Factors'] | 3,857,410 | [['D27.505.954.248'], ['A15.382.216'], ['G04.152'], ['A11.251'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539'], ['C04.557.337.539.275'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spontaneous thymoma in a juvenile cynomolgus macaque (Macaca fascicularis). | A single, solid, yellow-white thymic mass was found at necropsy of a two-year-old female cynomolgus macaque from a four-week, repeat-dose toxicity and immunogenicity study. Microscopically, the mass was multilobular and well encapsulated, surrounded by a thick connective tissue capsule, and composed of dense sheets of ... | ['Animals', 'Female', 'Immunohistochemistry', 'Macaca fascicularis', 'Thymoma', 'Thymus Gland', 'Thymus Neoplasms'] | 21,558,469 | [['B01.050'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['C04.557.435... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Early and long-term (one-year) effects of the association of aspirin and oral anticoagulant on thrombi and morbidity after replacement of the mitral valve with the St. Jude medical prosthesis: a clinical and transesophageal echocardiographic study. | OBJECTIVES: The aim of the study was to test the value of low dose aspirin associated with standard oral anticoagulants (OAC) after mechanical mitral valve replacement (MMRV) to reduce strands, thrombi and thromboembolic events.BACKGROUND: Strands and thrombi are thought to increase the risk of embolic events after MMV... | ['Administration, Oral', 'Anticoagulants', 'Aspirin', 'Drug Therapy, Combination', 'Echocardiography, Transesophageal', 'Female', 'Follow-Up Studies', 'Heart Valve Diseases', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Mitral Valve', 'Platelet Aggregat... | 10,716,478 | [['E02.319.267.100'], ['D27.505.954.502.119'], ['D02.455.426.559.389.657.410.595.176'], ['E02.319.310'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.484'], ['E07.695.310'], ['E04.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Risk, Overdiagnosis and Ethical Justifications. | Many healthcare practices expose people to risks of harmful outcomes. However, the major theories of moral philosophy struggle to assess whether, when and why it is ethically justifiable to expose individuals to risks, as opposed to actually harming them. Sven Ove Hansson has proposed an approach to the ethical assessm... | ['Clinical Decision-Making', 'Ethics', 'Humans', 'Medical Overuse', 'Preventive Medicine', 'Risk'] | 31,055,702 | [['E01.055'], ['K01.752.566.479', 'N05.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.380.450', 'N05.300.150.395.450'], ['H02.403.720.750'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Sonographic diagnosis and follow-up of diffuse neutropenic colitis: case report of a child treated for osteogenic sarcoma. | The sonographic features of total neutropenic colitis in a 14-year-old girl with osteogenic sarcoma are presented. Sonography disclosed characteristic diffuse thickening of the colonic wall with hyperechoic bowel mucosa. Serial sonograms were performed to monitor the progress of the disease. | ['Adolescent', 'Antineoplastic Combined Chemotherapy Protocols', 'Bone Neoplasms', 'Colitis', 'Colon', 'Female', 'Follow-Up Studies', 'Humans', 'Neutropenia', 'Osteosarcoma', 'Ultrasonography'] | 7,567,268 | [['M01.060.057'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.149', 'C05.116.231'], ['C06.405.205.265', 'C06.405.469.158.188'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Large-depth-of-field full-field optical angiography. | A large-depth-of-field full-field optical angiography (LD-FFOA) method is developed to expand the depth-of-field (DOF) using a contrast pyramid fusion algorithm (CPFA). The absorption intensity fluctuation modulation effect is utilized to obtain full-field optical angiography (FFOA) images at different focus positions.... | ['Angiography', 'Optical Imaging'] | 30,315,638 | [['E01.370.350.700.060', 'E01.370.370.050'], ['E01.370.350.589', 'E05.642']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insights into organ-specific pathogen defense responses in plants: RNA-seq analysis of potato tuber-Phytophthora infestans interactions. | BACKGROUND: The late blight pathogen Phytophthora infestans can attack both potato foliage and tubers. Although interaction transcriptome dynamics between potato foliage and various pathogens have been reported, no transcriptome study has focused specifically upon how potato tubers respond to pathogen infection. When i... | ['Disease Resistance', 'Gene Expression Profiling', 'Genomics', 'Genotype', 'Host-Pathogen Interactions', 'Organ Specificity', 'Phytophthora infestans', 'Plant Diseases', 'Plant Tubers', 'Plants, Genetically Modified', 'RNA, Messenger', 'Sequence Analysis, RNA', 'Solanum tuberosum'] | 23,702,331 | [['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['E05.393.332'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['G05.380'], ['G06.462', 'G16.527.200'], ['G07.650'], ['B01.750.580.715.600'], ['G15.610'], ['A18.400.625'], ['B01.650.520', 'B05.620.600'], ['D13.444.735.544'], ['E05.393.760.710'... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The incidence of mosquitoes feeding on mothers and babies at Kisumu, Kenya. | Blood fed mosquitoes were collected inside four bed nets in which mother/child pairs, having different haptoglobin types, slept. The bloodmeals were analysed by gradient gel electrophoresis to determine on which person the mosquitoes had fed. The results suggest that the mothers are fed on much more than babies by both... | ['Anopheles', 'Culex', 'Culicidae', 'Feeding Behavior', 'Female', 'Haptoglobins', 'Humans', 'Infant', 'Kenya'] | 25,970 | [['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.37... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Knowledge structures and linear separability: integrating information in object and social categorization. | These experiments were designed to determine if the naturalness of abstract category structures varies with content domain. Specifically, the degree to which linear separability constrains categorization was investigated in object and social domains. Linearly separable (LS) categories are categories that can be perfect... | ['Adult', 'Attention', 'Concept Formation', 'Female', 'Humans', 'Male', 'Mental Recall', 'Pattern Recognition, Visual', 'Personality', 'Problem Solving', 'Social Perception'] | 7,606,905 | [['M01.060.116'], ['F02.830.104.214'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F01.752'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.463.593.752']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Immunoglobulins in man. Biological properties and therapeutic aspects]. | The therapy with (modified) immune serum globulin implies critical limitation of therapeutic indications as well as the knowledge of the biological and physical properties of the immunoglobulin preparations. While the therapeutic effect in prophylaxis and substitution therapy is well established, the benefit has still ... | ['Antibody Formation', 'Antigen-Antibody Complex', 'Blood Platelets', 'Complement System Proteins', 'Humans', 'Immunization, Passive', 'Immunoglobulin Fragments', 'Immunoglobulins', 'Lymphocytes', 'Phagocytosis', 'Sepsis'] | 6,664,343 | [['G12.450.050.370.250'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['A11.118.188', 'A15.145.229.188'], ['D12.776.124.486.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['D12.644.541.500', 'D12.7... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A U.S. population dietary exposure assessment for 4-methylimidazole (4-MEI) from foods containing caramel colour and from formation of 4-MEI through the thermal treatment of food. | 4-Methylimidazole (4-MEI) is formed in caramel colours produced using ammonium compounds (Class III and Class IV caramel colours). 4-MEI can also form in food through Maillard reactions between reducing sugars and amino acids during cooking, roasting or dry-heating. The USFDA has analysed over 700 food and beverage sam... | ['Adolescent', 'Adult', 'Candy', 'Carbohydrates', 'Child', 'Child, Preschool', 'Cooking', 'Dietary Exposure', 'Food Contamination', 'Humans', 'Imidazoles', 'Infant', 'Molecular Structure', 'Temperature', 'United States', 'Young Adult'] | 30,130,454 | [['M01.060.057'], ['M01.060.116'], ['G07.203.300.140', 'J02.500.140'], ['D09'], ['M01.060.406'], ['M01.060.406.448'], ['J01.576.423.200.200'], ['N06.850.460.350.040'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['M01.0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Primary orbital meningioma: a study of six cases at a single institution. | Primary orbital meningioma is a rare tumor of the anterior visual pathway and constitutes approximately 2% of all orbital tumors and 1-2% of all meningiomas. The differentiation from secondary orbital meningioma of intracranial origin is sometimes difficult on image. As the tumor often leads to visual loss if left untr... | ['Adult', 'Female', 'Humans', 'Immunohistochemistry', 'Magnetic Resonance Imaging', 'Male', 'Meningioma', 'Middle Aged', 'Orbital Neoplasms', 'Tomography, X-Ray Computed'] | 21,143,524 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['E01.370.350.825... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Proteomic profiling of root system development proteins in chrysanthemum overexpressing the CmTCP20 gene. | Plant root systems ensure the efficient absorption of water and nutrients and provide anchoring into the soil. Although root systems are a highly plastic set of traits that vary both between and among species, the basic root system morphology is controlled by inherent genetic factors. TCP20 has been identified as a key... | ['Chlorophyll', 'Chromatography, High Pressure Liquid', 'Chrysanthemum', 'Gas Chromatography-Mass Spectrometry', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Indoleacetic Acids', 'Photosynthesis', 'Plant Growth Regulators', 'Plant Proteins', 'Plant Roots', 'Proteomics', 'Real-Time Polymerase Chain Reaction', '... | 31,481,217 | [['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['E05.196.181.400.300'], ['B01.650.940.800.575.912.250.100.206'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D03.066.288', 'D03.633.100.473.404'], ['G02.111.158.937', 'G02.111.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Robot-assisted laparoscopic versus open middle pancreatectomy: short-term results of a randomized controlled trial. | OBJECTIVE: This first prospective randomized controlled trial was performed to compare short-term outcomes of robot-assisted laparoscopic middle pancreatectomy (RA-MP) with open middle pancreatectomy (OMP).BACKGROUND: RA-MP is a novel minimally invasive surgical technique for benign or borderline tumors in the pancreat... | ['Female', 'Humans', 'Laparoscopy', 'Length of Stay', 'Male', 'Middle Aged', 'Operative Time', 'Pancreatectomy', 'Pancreatic Neoplasms', 'Postoperative Complications', 'Prospective Studies', 'Robotic Surgical Procedures', 'Treatment Outcome'] | 27,402,095 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['E04.210.752'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['C23.550.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Determination of the prognostic value of loss of heterozygosity at the retinoblastoma gene in osteosarcoma. | The retinoblastoma (RB) tumour suppressor gene is implicated in the development of several malignancies including osteosarcoma. Recent studies postulated its loss of heterozygosity (LOH) to be a poor prognostic factor at diagnosis of osteosarcoma (OS). It remains unclear whether LOH of the RB gene is suitable as a prog... | ['Adolescent', 'Adult', 'Antineoplastic Agents', 'Child', 'Child, Preschool', 'Electrophoresis, Agar Gel', 'Female', 'Humans', 'Loss of Heterozygosity', 'Male', 'Microsatellite Repeats', 'Osteosarcoma', 'Polymorphism, Genetic', 'Prognosis', 'Retinoblastoma Protein'] | 17,390,023 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.248'], ['M01.060.406'], ['M01.060.406.448'], ['E05.196.401.153', 'E05.301.300.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.029.530'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['C04.557.450.565.575.650... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Squamous cell carcinoma of bronchus: polypoid granules and mitochondrial densities found by electron microscopy. | In the course of studying a series of human bronchial and lung carcinomas by electron microscopy, we have come across a squamous cell (epidermoid) carcinoma containing two different kinds of small bodies that have not been described previously. One of them took the form of small round dense granules projecting from the... | ['Bronchial Neoplasms', 'Carcinoma, Squamous Cell', 'Cytoplasmic Granules', 'Humans', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Mitochondria'] | 7,140,505 | [['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'], ['A11.284.430.214.190.875.564', 'A... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Glycaemic rises after waking up in response to an alarm clock in type 1-diabetic patients analysed with continuous glucose monitoring (GlucoDay® S). | AIMS: Waking up in response to an alarm-clock may evoke a stress reaction that leads to rising glucose concentrations.METHOD: 30 type 1-diabetic patients participated in 3 overnight conditions: (a) with an alarm-clock set at 2 h intervals for glucose self monitoring, (b) with a nurse performing blood glucose determinat... | ['Adult', 'Arousal', 'Blood Glucose', 'Blood Glucose Self-Monitoring', 'Cross-Over Studies', 'Diabetes Mellitus, Type 1', 'Humans', 'Middle Aged', 'Prospective Studies', 'Stress, Psychological'] | 21,246,465 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['D09.947.875.359.448.500'], ['E01.370.225.124.100.105', 'E01.370.374.100', 'E01.370.520.100', 'E02.900.950.500', 'E05.200.124.100.105'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phakic posterior chamber lenses for high myopia: functional and anatomical outcomes. | PURPOSE: To evaluate the functional and the anatomical outcomes after implantation of phakic posterior chamber intraocular lenses (IOLs) in highly myopic eyes.SETTING: Service d'Ophtalmologie, H?pital Purpan, Toulouse, France.METHODS: Fifty-eight eyes of 46 patients that had implantation of phakic posterior chamber len... | ['Adult', 'Aqueous Humor', 'Cell Count', 'Endothelium, Corneal', 'Fluorophotometry', 'Humans', 'Lens Implantation, Intraocular', 'Lens, Crystalline', 'Lenses, Intraocular', 'Myopia', 'Prognosis', 'Refraction, Ocular', 'Retina', 'Visual Acuity'] | 10,713,231 | [['M01.060.116'], ['A09.371.060.067.070', 'A12.207.270.040'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A09.371.060.067.318', 'A09.371.060.217.318', 'A10.272.491.318'], ['E01.370.380.255', 'E05.196.712.516.600.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['A... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reduction of silicone particle release during haemodialysis. | Spallation of silicone was evaluated in an in vitro system, using a commercial blood pump and dialysis tubing. Silicone particle release was assessed at various occlusion forces (5.5-22 kp). When the occlusion force was reduced from 22 to 5.5 kp, the number of released silicone particles decreased by approximately 80 p... | ['In Vitro Techniques', 'Kidneys, Artificial', 'Renal Dialysis', 'Silicones'] | 3,991,512 | [['E05.481'], ['E07.858.082.585'], ['E02.870.300', 'E02.912.800'], ['D02.756.650.700', 'D05.750.900.850', 'D25.720.900.850', 'J01.637.051.720.900.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. | Deltamethrin [(S)-alpha-cyano-3-phenoxybenzyl-cis-(1 R,3R)-3(2,2-dibromovinyl)(2,2-dimethyl-cyclopropane-carboxylate] and permethrin [3-phenoxybenzyl(1RS)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylate] are pyrethroid insecticides used in agriculture, public health and military deployments. Pyreth... | ['Adenylate Kinase', 'Adult', 'Caspase 3', 'Caspase 7', 'Cell Death', 'Cells, Cultured', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 Enzyme System', 'Dose-Response Relationship, Drug', 'Enzyme Induction', 'Gene Expression Regulation, Enzymologic', 'Hepatocytes', 'Humans', 'Insecticides', 'Isoenzymes', 'Nitriles', 'Perm... | 19,326,768 | [['D08.811.913.696.650.025'], ['M01.060.116'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126.350.700', 'D08.811.277.656.300.200.126.350.700', 'D12.644.360.075.405.350.700', 'D12.776.476.075.405.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alanine and terbutaline in treatment of hypoglycemia in IDDM. | OBJECTIVE: To test the hypothesis that, in contrast to administration of glucose or glucagon, administration of the amino acid Ala or of the beta 2-adrenergic agonist terbutaline produces sustained glucose recovery from hypoglycemia.RESEARCH DESIGN AND METHODS: We developed a model of clinical hypoglycemia using subcut... | ['3-Hydroxybutyric Acid', 'Administration, Oral', 'Alanine', 'Blood Glucose', 'C-Peptide', 'Diabetes Mellitus, Type 1', 'Epinephrine', 'Fatty Acids, Nonesterified', 'Glucagon', 'Humans', 'Hydroxybutyrates', 'Hypoglycemia', 'Injections, Subcutaneous', 'Insulin', 'Lactates', 'Pancreatic Polypeptide', 'Terbutaline', 'Time... | 8,375,243 | [['D02.241.081.114.937.349', 'D02.241.511.429.349', 'D02.522.585.087', 'D10.251.400.143.781.500'], ['E02.319.267.100'], ['D12.125.042'], ['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D02.033.100.291.310', 'D02.092.06... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Representation and propagation of epileptic activity in absences and generalized photoparoxysmal responses. | Although functional imaging studies described networks associated with generalized epileptic activity, propagation patterns within these networks are not clear. In this study, electroencephalogram (EEG)-based coherent source imaging dynamic imaging of coherent sources (DICS) was applied to different types of generalize... | ['Brain', 'Brain Mapping', 'Electroencephalography', 'Epilepsy', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Signal Processing, Computer-Assisted'] | 22,431,268 | [['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['L01.224.800']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Expression studies of two novel in CIS-mutations identified in an intermediate case of Hunter syndrome. | Hunter syndrome (Mucopolysaccharidosis type II) is a rare X-linked recessive lysosomal storage disorder caused by the deficiency of the enzyme iduronate-2-sulfatase (IDS). To date, more than 200 different mutations have been reported in the IDS gene, located on Xq27.3-q28. Here, we report two new mutations (M488I and G... | ['Animals', 'Base Sequence', 'COS Cells', 'DNA Mutational Analysis', 'DNA, Complementary', 'Genetic Counseling', 'Genetic Linkage', 'Genotype', 'Humans', 'Iduronate Sulfatase', 'In Vitro Techniques', 'Molecular Sequence Data', 'Mucopolysaccharidosis II', 'Mutagenesis, Site-Directed', 'Mutation', 'Oligonucleotides', 'Ph... | 12,794,697 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.172.500', 'A11.329.228.220'], ['E05.393.760.700.300'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['G05.348'], ['G05.380'], ['B01.050.150.900.649... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Dual action of isoflurane on the gamma-aminobutyric acid (GABA)-mediated currents through recombinant alpha(1)beta(2)gamma(2L)-GABA(A)-receptor channels. | Isoflurane (ISO) increased the agonist-induced chloride flux through the gamma-aminobutyric acid A receptor (GABA(A)R). This may reflect an anesthetic-induced increase in the apparent agonist affinity. A dual effect of anesthetics was postulated for both the nicotinic acetylcholine receptor (nAChR) and the GABA(A)R. We... | ['Anesthetics, Inhalation', 'Animals', 'Cell Line', 'Chloride Channels', 'Electrophysiology', 'Humans', 'Isoflurane', 'Patch-Clamp Techniques', 'Rats', 'Receptors, GABA-A', 'Recombinant Proteins', 'Transfection', 'gamma-Aminobutyric Acid'] | 10,781,477 | [['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['B01.050'], ['A11.251.210'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.355.601.570'], ['E05.200.500.905', 'E05.242... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Genome inside genome: NGS based identification and assembly of endophytic Sphingopyxis granuli and Pseudomonas aeruginosa genomes from rice genomic reads. | The interactions between crop plants and the endophytic bacteria colonizing them are poorly understood and experimental methods were found to be inadequate to meet the complexities associated with the interaction. Moreover, research on endophytic bacteria was focused at host plant species level and not at cultivar leve... | ['Endophytes', 'Genome, Bacterial', 'Genome, Plant', 'High-Throughput Nucleotide Sequencing', 'Oryza', 'Proteobacteria', 'Sequence Analysis, DNA', 'Software'] | 28,192,179 | [['B05.237'], ['G05.360.340.358.207'], ['G05.360.340.365'], ['E05.393.760.319'], ['B01.650.940.800.575.912.250.822.616'], ['B03.660'], ['E05.393.760.700'], ['L01.224.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Light exposure inhibiting tissue browning and improving antioxidant capacity of fresh-cut celery (Apium graveolens var. dulce). | Fresh-cut celery is perishable and susceptible to tissue browning during storage. In this study, the effect of continuous light exposure (2000 lux) on browning related enzyme activity of fresh-cut celery was investigated during 8d storage at 7 °C using darkness (0.2 lux) as control. Light exposure significantly suppres... | ['Antioxidants', 'Apium', 'Catechol Oxidase', 'Color', 'Food Preservation', 'Food Storage', 'Light', 'Peroxidase', 'Phenols', 'Plant Proteins', 'Vegetables'] | 23,870,983 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.650.940.800.575.912.250.075.094'], ['D08.811.682.690.708.125'], ['G01.590.540.199'], ['J01.576.423.850.700'], ['J01.576.423.200.387'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D08.811.682.732.700'], ['D02.455.42... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
How close is the dose? Manipulation of 10 mg hydrocortisone tablets to provide appropriate doses to children. | This study explores the methodology advised by healthcare professionals and the methods used by parents/carers to identify whether there is a best practice method for manipulation of 10 mg hydrocortisone tablets to provide an accurate dose to children. Bespoke surveys were used to identify methods recommended and used ... | ['Administration, Oral', 'Adolescent', 'Age Factors', 'Anti-Inflammatory Agents', 'Benchmarking', 'Caregivers', 'Child', 'Child, Preschool', 'Drug Compounding', 'Drug Dosage Calculations', 'Female', 'Health Care Surveys', 'Humans', 'Hydrocortisone', 'Infant', 'Male', 'Parents', 'Tablets', 'Young Adult'] | 29,705,101 | [['E02.319.267.100'], ['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.954.158'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.060.406.448'], ['E05.916.270'], ['E02.319.305'], ['E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
NDRAM: nonlinear dynamic recurrent associative memory for learning bipolar and nonbipolar correlated patterns. | This paper presents a new unsupervised attractor neural network, which, contrary to optimal linear associative memory models, is able to develop nonbipolar attractors as well as bipolar attractors. Moreover, the model is able to develop less spurious attractors and has a better recall performance under random noise tha... | ['Algorithms', 'Artificial Intelligence', 'Biomimetics', 'Cluster Analysis', 'Computer Simulation', 'Feedback', 'Memory', 'Models, Theoretical', 'Neural Networks, Computer', 'Nonlinear Dynamics', 'Pattern Recognition, Automated', 'Statistics as Topic'] | 16,342,483 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['H01.158.550.100', 'J01.897.120.100'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.160'], ['L01.906.394.211'], ['F02.463.425.540'], ['E05.599'], ['G17.485', 'L01.224.050.375.605'], ['E05.599.850', 'H01.548.675'], ['L01.39... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Surface antigens of Leishmania donovani promastigotes. | Surface antigen profiles of Leishmania donovani promastigote isolates have been studied. Surface patterns of Brazilian and African isolates display remarkable similarities and are extremely simple, consisting of three major peptides of 65,000, 25,000, and 23,000 mol wt. Surface iodination and biosynthetic labeling coup... | ['Animals', 'Antigens, Surface', 'Brazil', 'Cross Reactions', 'Dogs', 'Humans', 'Leishmania', 'Leishmaniasis, Visceral', 'Molecular Weight', 'Peptides', 'Sepharose', 'Sudan'] | 6,854,205 | [['B01.050'], ['D23.050.301'], ['Z01.107.757.176'], ['G12.122.281'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.268.475.868.488'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['G02.494'], ['D12.644'], ['D09.698.813'], ['Z01.058.290.120.760']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Identification and Validation of SNP Markers Linked to Dwarf Traits Using SLAF-Seq Technology in Lagerstroemia. | The genetic control of plant architecture is a promising approach to breed desirable cultivars, particularly in ornamental flowers. In this study, the F1 population (142 seedlings) derived from Lagerstroemia fauriei (non-dwarf) ? L. indica 'Pocomoke' (dwarf) was phenotyped for six traits (plant height (PH), internode l... | ['Genetic Markers', 'Genotype', 'High-Throughput Nucleotide Sequencing', 'Lagerstroemia', 'Phenotype', 'Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide'] | 27,404,662 | [['D23.101.387', 'G05.695.450'], ['G05.380'], ['E05.393.760.319'], ['B01.650.940.800.575.912.250.859.833.500.374'], ['G05.695'], ['E05.393.620.500'], ['G05.365.795.598']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of color and luminance discrimination in amblyopia. | Using isochromatic luminance gratings and isoluminant red-green color gratings, examined luminance and color discrimination in amblyopia were examined. Complete color and luminance contrast sensitivity functions were measured monocularly from each eye of six normal and six amblyopic observers. Similar spatial frequency... | ['Amblyopia', 'Color Perception', 'Humans', 'Light', 'Space Perception', 'Visual Perception'] | 3,744,730 | [['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['F02.463.593.932.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['F02.463.593.778'], ['F02.463.593.932']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prenatal detection of chromosome aneuploidies by fluorescence in situ hybridization: experience with 2000 uncultured amniotic fluid samples in a prospective preclinical trial. | Successful rapid prenatal detection of selected numerical chromosome abnormalities by using fluorescence in situ hybridization (FISH) on uncultured amniotic fluid samples has been described by Klinger et al. (1992) and Ward et al. (1993, 1997). Using essentially the same FISH protocol and identical probes specific for ... | ['Amniotic Fluid', 'Aneuploidy', 'Chromosomes, Human, Pair 13', 'Chromosomes, Human, Pair 18', 'Chromosomes, Human, Pair 21', 'Female', 'Humans', 'In Situ Hybridization, Fluorescence', 'Karyotyping', 'Pregnancy', 'Prenatal Diagnosis', 'Prospective Studies', 'Sex Chromosomes'] | 9,160,386 | [['A12.098', 'A16.378.149'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['A11.284.187.520.300.370.375', 'G05.360.162.520.300.370.375'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['B01.050.150.900.649.313.988.400.112.40... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Proteins with H-bond packing defects are highly interactive with lipid bilayers: Implications for amyloidogenesis. | We noticed that disease-related amyloidogenic proteins and especially cellular prion proteins have the highest proportion of incompletely desolvated backbone H bonds among soluble proteins. Such bonds are vulnerable to water attack and thus represent structural weaknesses. We have measured the adsorption of proteins on... | ['Adsorption', 'Amino Acid Motifs', 'Amyloid', 'Animals', 'Biophysical Phenomena', 'Biophysics', 'Cell Membrane', 'Databases as Topic', 'Humans', 'Hydrogen Bonding', 'Kinetics', 'Lipid Bilayers', 'Models, Molecular', 'Protein Folding', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'Proteins', 'Time Fac... | 12,591,960 | [['G01.030', 'G02.020'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['D05.500.049', 'D12.776.049'], ['B01.050'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['A11.284.149'], ['L01.313.500.750.300.188', 'L01.470.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['G01.374.661', 'G... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
High-throughput immunoassay for the biochemical diagnosis of Friedreich ataxia in dried blood spots and whole blood. | BACKGROUND: Friedreich ataxia (FRDA) is caused by reduced frataxin (FXN) concentrations. A clinical diagnosis is typically confirmed by DNA-based assays for GAA-repeat expansions or mutations in the FXN (frataxin) gene; however, these assays are not applicable to therapeutic monitoring and population screening. To faci... | ['Adult', 'Dried Blood Spot Testing', 'Female', 'Friedreich Ataxia', 'High-Throughput Screening Assays', 'Humans', 'Immunoassay', 'Infant, Newborn', 'Iron-Binding Proteins', 'Male', 'Reference Values'] | 23,838,345 | [['M01.060.116'], ['E01.370.225.124.100.232', 'E05.200.124.100.232'], ['C10.228.140.252.700.150', 'C10.228.854.787.200', 'C10.574.500.825.200', 'C16.320.400.780.200', 'C18.452.660.300'], ['E05.916.680'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['M01.060.703.520'], ['D12.776.157.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of round ended needles for high dose rate brachytherapy implants. | The use of Speiser needles for interstitial implants has resulted in malfunctioning of HDR afterloading equipment due to seepage of blood. We have successfully used rounded ended needles in the patient after removal of the trocar ended needles, preventing the seepage of blood. This technique also helps to prevent any p... | ['Brachytherapy', 'Equipment Contamination', 'Equipment Design', 'Humans', 'Male', 'Needles', 'Prostatic Neoplasms', 'Radiotherapy Dosage'] | 10,740,890 | [['E02.815.150'], ['N06.850.540'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.612'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.639']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Thrombocytosis Associated with Poor Prognosis in Patients with Gastric Cancer]. | BACKGROUND: Thrombocytosis in patients with cancer is reportedly associated with an increased expression of angiogenic factors and a poor prognosis in some cancer types. The aim of this study was to analyze the clinicopathological significance and prognostic value of platelet counts in patients with gastric cancer.METH... | ['Aged', 'Female', 'Humans', 'Male', 'Neoplasm Staging', 'Platelet Count', 'Prognosis', 'Stomach Neoplasms', 'Thrombocytosis'] | 26,805,237 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.225.625.625.625', 'E05.200.500.195.107.740', 'E05.200.625.107.700', 'E05.200.625.625.625', 'E05.242.195.107.740', 'G04.140.107.740', 'G09.188.105.700'], ['E01.789']... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Prevalence of renal infarcts in autopsies of chronic Chagas disease patients]. | Renal infarction (RI) is usually secondary to arterial obstruction due to emboli originating from the heart. Chronic chagasic patients may present cardiac alterations originating from intracavitary thrombi, even without congestive heart failure (CHF). In this study RI incidence was comparatively evaluated in chronic ch... | ['Adult', 'Chagas Disease', 'Female', 'Humans', 'Infarction', 'Kidney', 'Male', 'Sex Distribution'] | 9,011,882 | [['M01.060.116'], ['C01.610.752.300.900.200', 'C01.920.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513.355', 'C23.550.717.489'], ['A05.810.453'], ['I01.240.800', 'N01.224.803', 'N06.850.505.400.850']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Simulations in drug training. | A simulation over a five-day period allowing clinicians to become patients and apply what they experience is presented as a vehicle from which important learning can take place to help clinicians function better within clinical work environments. The simulation gave clinical trainers and trainees in the drug field mutu... | ['Allied Health Personnel', 'Attitude of Health Personnel', 'Crisis Intervention', 'Curriculum', 'Empathy', 'Evaluation Studies as Topic', 'Humans', 'Methadone', 'Professional-Patient Relations', 'Psychiatry', 'Psychodrama', 'Role Playing', 'Substance-Related Disorders', 'Teaching', 'Therapeutic Community', 'Time Facto... | 1,211,380 | [['M01.526.485.067', 'N02.360.067'], ['F01.100.050', 'N05.300.100'], ['F04.754.252'], ['I02.158'], ['F01.752.355', 'F01.752.543.500.500'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522.675'], ['F01.829.401.650', 'N05.300.660'], ['F04.096.544', 'H02.403.690'], ['E02.190.525.7... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and P... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Activation of the cAMP-protein kinase A pathway facilitates Na+ translocation by the Na+-K+ pump in guinea-pig ventricular myocytes. | 1. The effects of the adenylyl cyclase activator forskolin on steady-state and transient currents generated by the Na+-K+ pump were studied in guinea-pig ventricular myocytes by means of whole-cell voltage clamp at 30 C. 2. In external solution containing 144 mM Na+ (Na+o) and 10 mM K+ (K+o), steady-state Na+-K+ pump c... | ['Adenylyl Cyclases', 'Animals', 'Biological Transport', 'Cells, Cultured', 'Colforsin', 'Cyclic AMP-Dependent Protein Kinases', 'Electric Conductivity', 'Electrophysiology', 'Enzyme Activation', 'Enzyme Inhibitors', 'Guinea Pigs', 'Heart Ventricles', 'Isoquinolines', 'Myocardium', 'Sodium', 'Sodium-Potassium-Exchangin... | 10,718,738 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['G03.143'], ['A11.251'], ['D02.455.849.291.300'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['G01.358.500.249.277'], ['H01.158.344.528', 'H01.158.782.236'], ['G02.111.263', 'G03.328'], ['D27.505.51... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Medication-related attitudes of chronic schizophrenic patients. A follow-up study after psycho-educational intervention]. | OBJECTIVE: To evaluate the effect of a psychoeducational training, compliance, medication management, and illness-related attitudes were assessed among schizophrenic outpatients.METHODS: Study patients who attended at least 70% of 10 psychoeducational sessions (n = 74) and the 57 patients of the control group were reex... | ['Adult', 'Antipsychotic Agents', 'Female', 'Follow-Up Studies', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Patient Compliance', 'Patient Education as Topic', 'Patient Satisfaction', 'Program Evaluation', 'Psychiatric Status Rating Scales', 'Schizophrenia', 'Schizophrenic Psychology', 'Self Care', 'Sic... | 9,530,765 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.600', 'F0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Some aspects of aging in the lumbar spine. | I measured the bodies of vertebrae L3 and L4 of 338 skeletons from the Terry collection in the Smithsonian Institution, including Blacks and Whites, males and females, aged from 20 to 90 years. Transverse breadths of the upper and lower endplates (excluding osteophytes) and minimum transverse breadths all increase with... | ['Adult', 'African Continental Ancestry Group', 'Aged', 'Aging', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Osteoporosis', 'Sex Factors'] | 998,754 | [['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['G07.345.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C05.116.198.579', 'C18.452.104.579'], ['N05.715.350.675', 'N06.850.490.875']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake. | Dopamine (DA) is a modulatory neurotransmitter controlling motor activity, reward processes and cognitive function. Impairment of dopaminergic (DAergic) neurotransmission is strongly associated with several central nervous system-associated diseases such as Parkinson's disease, attention-deficit-hyperactivity disorder ... | ['Animals', 'Chromatography, High Pressure Liquid', 'Dopamine', 'Dopamine Plasma Membrane Transport Proteins', 'Homeostasis', 'Male', 'Mice', 'Synaptosomes'] | 28,994,779 | [['B01.050'], ['E05.196.181.400.300'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D12.776.157.530.450.625.124', 'D12.776.157.530.562.374.500.500', 'D12.776.157.530.937.500', 'D12.776.543.585.450.625.124', 'D12.776.543.585.562.374.500.500', 'D12.776.543.585.937.500'], ['G07.410'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liver injury may increase the risk of diazoxide toxicity: a case report. | UNLABELLED: Stress-related hyperinsulinism (HI) may lead to recalcitrant hypoglycemia for weeks or months following perinatal stress, often in premature newborn infants. Diazoxide is an effective and usually safe medication to treat this type and other types of neonatal HI. We report a male infant born at 35-week gesta... | ['Albumins', 'Blood Glucose', 'Chemical and Drug Induced Liver Injury', 'Diazoxide', 'Heart Failure', 'Humans', 'Hyperinsulinism', 'Hypoglycemia', 'Infant, Newborn', 'Liver', 'Liver Function Tests', 'Male', 'Respiratory Insufficiency', 'Vasodilator Agents'] | 25,618,267 | [['D12.776.034'], ['D09.947.875.359.448.500'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['D02.886.590.700.135.300', 'D02.886.655.500.300', 'D03.633.100.174.300'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968'], ['C18.452.394.984'], ['M01.060.703.520'], ['A03.620'], ['E01.370... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment of diabetic orthostatic hypotension with pindolol. | The hemodynamic variables, plasma noradrenaline and plasma renin concentrations were studied in a 57-year-old female with insulin-dependent diabetes of long-standing and orthostatic hypotension. For 6 months she had been bedridden because of severe orthostatic symptoms. Reflex responses in the heart rate and blood pres... | ['Autonomic Nervous System Diseases', 'Blood Pressure', 'Diabetic Neuropathies', 'Female', 'Heart Rate', 'Humans', 'Middle Aged', 'Norepinephrine', 'Pindolol', 'Renin', 'Sympathetic Nervous System'] | 6,753,448 | [['C10.177'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.668.829.300', 'C19.246.099.937'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.65... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer. | Dichloroacetate (DCA), an orphan drug that promotes a shift from glycolysis to oxidative phosphorylation, has been repurposed for cancer therapy. The present study investigated whether DCA may overcome cisplatin resistance in head and neck cancer (HNC). Two cisplatin-resistant HNC cell lines (AMC-HN4R and -HN9R), their... | ['Animals', 'Antineoplastic Agents', 'Antioxidants', 'Apoptosis', 'Caspase Inhibitors', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Survival', 'Cisplatin', 'Dichloroacetic Acid', 'Dose-Response Relationship, Drug', 'Drug Resistance, Neoplasm', 'Enzyme Inhibitors', 'Glycolysis', 'Head and Neck Neoplasms', 'Human... | 26,607,904 | [['B01.050'], ['D27.505.954.248'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D27.505.519.389.745.325.500'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D02.241.081.018.214.500', 'D02.455.526.439.196.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The prognostic significance of CXCL16 and its receptor C-X-C chemokine receptor 6 in prostate cancer. | The chemokine CXCL16 and its receptor, C-X-C chemokine receptor (CXCR6), affect tumor progression through different pathways, including leukocyte recruitment and function, cellular senescence, tumor cell proliferation, survival, invasion, and metastasis. We examined how the expression of CXCL16/CXCR6 in prostate cancer... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cell Line, Tumor', 'Cell Proliferation', 'Chemokine CXCL16', 'Chemokines, CXC', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Prognosis', 'Prostatic Neoplasms', 'Receptors, CXCR6', 'Receptors, Chemokine', 'Receptors, Scavenger', 'Receptors, Virus'] | 26,272,362 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374.200.120.075', 'D12.776.467.374.200.120.075', 'D12.776.503.280.718.500', 'D12.776.543.750.705.940.734.500', 'D12.776.543.750.710.450.625.500.500', 'D12.776.543... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Perturbed energy balance and hydration status in ultra-endurance runners during a 24 h ultra-marathon. | The present study aimed to assess the adequacy of energy, macronutrients and water intakes of ultra-endurance runners (UER) competing in a 24 h ultra-marathon (distance range: 122-208 km). The ad libitum food and fluid intakes of the UER (n 25) were recorded throughout the competition and analysed using dietary analysi... | ['Adult', 'Body Water', 'Diet', 'Dietary Carbohydrates', 'Dietary Fats', 'Dietary Proteins', 'Drinking', 'Energy Intake', 'Energy Metabolism', 'Female', 'Gastrointestinal Diseases', 'Humans', 'Male', 'Middle Aged', 'Osmolar Concentration', 'Physical Endurance', 'Plasma Volume', 'Running'] | 24,818,799 | [['M01.060.116'], ['A12.207.200'], ['G07.203.650.240'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.283.249', 'G10.261.330.249'], ['G07.203.650.240.340'], ['G03.295'], ['C06.405'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
Microorganism inactivation using high-pressure generation in sealed vessels under sub-zero temperature. | In order to test the possibility of utilizing high pressure in bioscience and biotechnology, a simple method for high-pressure generation and its use for microbial inactivation have been studied. When a pressure vessel was filled with water, sealed tightly and cooled to sub-zero temperatures, high pressure was generate... | ['Bacteria', 'Cold Temperature', 'Colony Count, Microbial', 'Freezing', 'Frozen Foods', 'Fungi', 'Medical Waste Disposal', 'Pressure', 'Spores, Fungal', 'Sterilization', 'Time Factors'] | 9,830,091 | [['B03'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['G07.203.300.521.500', 'J02.500.521.500'], ['B01.300'], ['D20.944.460.300... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity. | The intercalated disk (ID), a highly organized adhesion structure connecting neighboring cardiomyocytes, fulfills mechanical and electrical signaling communication to ensure normal heart function. Lipoprotein receptor-related protein 6 (LRP6) is a co-receptor inducing canonical Wnt/â-catenin signaling. It was recently ... | ['Animals', 'Cadherins', 'Catenins', 'Cell Membrane', 'Cells, Cultured', 'Connexin 43', 'Desmoplakins', 'Low Density Lipoprotein Receptor-Related Protein-6', 'Male', 'Mice', 'Myocytes, Cardiac', 'Protein Binding'] | 31,609,038 | [['B01.050'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['D12.776.220.145'], ['A11.284.149'], ['A11.251'], ['D12.776.543.585.250.200'], ['D12.776.220.790.500'], ['D12.776.526.600', 'D12.776.543.750.710.450.500.600', 'D12.776.543.750.850.781'], ['B01.050.150.900.649.313.992.635.505.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The endogenous á7 nicotinic acetylcholine receptor antagonist kynurenic acid modulates amyloid-â-induced inflammation in BV-2 microglial cells. | Amyloid-â has been shown to interact with the á7 nicotinic acetylcholine receptor on neuronal cells. Not much is known on the effect on microglial cells and whether this effect can be modulated by the endogenous á7 nicotinic acetylcholine receptor antagonist kynurenic acid. Our aim was to investigate the effect of kynu... | ['Amyloid beta-Peptides', 'Animals', 'Cell Line, Transformed', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Enzyme-Linked Immunosorbent Assay', 'Excitatory Amino Acid Antagonists', 'Interleukin-6', 'Kynurenic Acid', 'Mice', 'Mice, Inbred C57BL', 'Microglia', 'Nitric Oxide', 'Peptide Fragments', 'Phagocytosis',... | 25,064,444 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['A11.251.210.172'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D27.505.519.625.190.300', 'D27.505.696.577.190... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myelopreservation with the CDK4/6 inhibitor trilaciclib in patients with small-cell lung cancer receiving first-line chemotherapy: a phase Ib/randomized phase II trial. | BACKGROUND: Chemotherapy-induced damage of hematopoietic stem and progenitor cells (HSPC) causes multi-lineage myelosuppression. Trilaciclib is an intravenous CDK4/6 inhibitor in development to proactively preserve HSPC and immune system function during chemotherapy (myelopreservation). Preclinically, trilaciclib trans... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Brain Neoplasms', 'Carboplatin', 'Cisplatin', 'Cyclin-Dependent Kinase 4', 'Cyclin-Dependent Kinase 6', 'Double-Blind Method', 'Etoposide', 'Female', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Male', 'Maximum Tolerated Dose... | 31,504,118 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D02.257.125'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D08.811.913.696.620.682.700.646.500.875', 'D12.644.360.250.451', 'D1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Myasthenia gravis following viral infection. | The pathogenesis of myasthenia gravis is autoimmune, the real etiology, however, remains unknown. Virus has been suggested as an etiological agent of the disease. In this study we present 5 myasthenic patients, whose symptoms began a few weeks after a proven viral infection. The possibility of viral infection as etiolo... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Measles', 'Myasthenia Gravis', 'Virus Diseases'] | 7,308,244 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.782.580.600.500.500'], ['C04.588.614.550.500', 'C04.730.856.490', 'C10.114.656', 'C10.574.781.588', 'C10.668.758.725', 'C20.111.258.500'], ['C01.925']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incidence of priapism in the general population. | OBJECTIVES: To assess the incidence of priapism in the general population.METHODS: We conducted a population-based retrospective cohort study within a general practitioners research database. Our study population comprised all male patients with permanent registration status with a general practitioner. All patients wi... | ['Adult', 'Age Factors', 'Cohort Studies', 'Follow-Up Studies', 'Health Surveys', 'Humans', 'Incidence', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Netherlands', 'Poisson Distribution', 'Priapism'] | 11,337,305 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Activating P2X7 Receptors Increases Proliferation of Human Pancreatic Cancer Cells via ERK1/2 and JNK. | OBJECTIVES: The aim of this study was to investigate the effects of the activated P2X7 receptors on the proliferation and growth of human pancreatic cancer cells.METHODS: Proliferation was measured by incorporating bromodeoxyuridine into pancreatic cancer cells, MIA PaCa-2 and HPAC. Expression of P2 receptors and signa... | ['Adenosine Triphosphate', 'Animals', 'Cell Line, Tumor', 'Cell Proliferation', 'Extracellular Signal-Regulated MAP Kinases', 'Gene Expression Regulation, Neoplastic', 'Humans', 'JNK Mitogen-Activated Protein Kinases', 'Male', 'Mice, Inbred BALB C', 'Mice, Nude', 'Mitogen-Activated Protein Kinases', 'Pancreatic Neoplas... | 29,683,976 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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