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Electrophysiological evidence for a functional interaction between 5-HT1A and 5-HT2A receptors in the rat medial prefrontal cortex: an iontophoretic study. | In this study, we examined the interaction of 5-HT1A and 5-HT2A receptors in the rat medial prefrontal cortex (mPFc) using the techniques of extracellular single unit recording and microiontophoresis. The iontophoresis of the selective 5-HT1A receptor agonist (+-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-OHDPAT) prod... | ['Amphetamines', 'Animals', 'Electrophysiology', 'Fluorobenzenes', 'Glutamic Acid', 'Injections, Intravenous', 'Iontophoresis', 'Male', 'Organic Chemicals', 'Piperidines', 'Prefrontal Cortex', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Serotonin', 'Serotonin', 'Serotonin Antagonists', 'Serotonin Receptor Agonists'] | 7,974,200 | [['D02.092.471.683.152'], ['B01.050'], ['H01.158.344.528', 'H01.158.782.236'], ['D02.455.426.559.389.358', 'D02.455.526.510.432'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E02.319.267.650', 'E05.301.300.575'], ['D02'], ['D03.383.621'], ['A08.18... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of different durations and formulations of diltiazem on the single-dose pharmacokinetics of midazolam: how long do we go? | Understanding how inhibition of cytochrome P4503A (CYP3A) affects the metabolism of a new drug is critical in determining if a clinically relevant drug interaction will occur. Diltiazem interaction studies assess a given compound's sensitivity to moderate CYP3A inhibition. The present study compared the effect differen... | ['Adult', 'Area Under Curve', 'Chemistry, Pharmaceutical', 'Cross-Over Studies', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 CYP3A Inhibitors', 'Diltiazem', 'Drug Interactions', 'Female', 'Humans', 'Ketoconazole', 'Male', 'Midazolam', 'Middle Aged', 'Sensitivity and Specificity', 'Young Adult'] | 21,209,240 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['H01.158.703.007', 'H01.181.466'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.690.708.170.495.500', 'D12.776.422.220.453.860.500'], ['D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The prevalence of psychiatric morbidity and its associated factors in general health care in Taiwan. | BACKGROUND: This paper reports the prevalence, disability, sociodemographic and clinical association of psychiatric morbidity among attenders in general health care in Taiwan where, as in the rest of non-Western countries, few studies have been carried out.METHODS: A cross-sectional survey with a two-phase design was c... | ['Adolescent', 'Adult', 'Aged', 'Comorbidity', 'Cross-Cultural Comparison', 'Cross-Sectional Studies', 'Family Practice', 'Female', 'Health Surveys', 'Hospitals, General', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Psychophysiologic Disorders', 'Sampling Studies', 'Taiwan'] | 12,102,377 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['H02.403.340.500'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Dlgh1 and Carma1 MAGUK proteins contribute to signal specificity downstream of TCR activation. | Mitogen-activated protein kinases (MAPKs), including p38 and c-Jun N-terminal kinase (JNK), have a key role in T cell receptor (TCR)-induced gene transcription but their precise mechanism of activation is not well understood. The findings of two recent papers provide new insight into the activation of p38 and JNK by th... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Apoptosis Regulatory Proteins', 'CARD Signaling Adaptor Proteins', 'Cell Line', 'Discs Large Homolog 1 Protein', 'Enzyme Activation', 'Guanylate Kinases', 'Humans', 'MAP Kinase Kinase 4', 'Membrane Proteins', 'Mice', 'Mitogen-Activated Protein Kinases', 'Receptors, A... | 17,395,537 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.644.360.024.131', 'D12.644.360.075.358', 'D12.776.157.057.006', 'D12.776.476.024.139', 'D12.776.476.075.358'], ['A11.251.210'], ['D08.811.913.696.650.450.500', 'D12.644.360.024.287', 'D12.776.157.057.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feasibility of using the cystic duct for biliary reconstruction in right-lobe living donor liver transplantation. | Duct-to-duct biliary reconstruction has been introduced in adult living donor liver transplantation (LDLT). In right-lobe grafts, however, the presence of two or three separated bile duct orifices is not rare and makes an alternative approach for reconstruction necessary. We used the cystic duct for one of the anastomo... | ['Adolescent', 'Adult', 'Anastomosis, Surgical', 'Bile Ducts', 'Cohort Studies', 'Cystic Duct', 'Feasibility Studies', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'Graft Survival', 'Humans', 'Liver Failure', 'Liver Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Reconstructive Surgical Procedures', 'Ri... | 16,237,710 | [['M01.060.057'], ['M01.060.116'], ['E04.035'], ['A03.159.183'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A03.159.183.079.450'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Properties of the citrate transporter in rat heart: implications for regulation of glycolysis by cytosolic citrate. | The efflux of [14C]citrate from rat heart mitochondria was significantly greater with L-malate as the extramitochondrial substrate as compared with [12C]citrate, isocitrate or phosphoenolpyruvate. The concentration of L-malate required for half-maximal rate of efflux of citrate was 0.45 mM and the maximum velocity was ... | ['Animals', 'Binding, Competitive', 'Biological Transport, Active', 'Citrates', 'Cytosol', 'Glycolysis', 'Kinetics', 'Malates', 'Mitochondria, Muscle', 'Myocardium', 'Rats'] | 1,276,981 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G03.143.310'], ['D02.241.081.901.434'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['G01.374.661', 'G02.111.490'], ['D02.241.081.337.463', 'D02.241.511.505... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hyaluronic acid deposition in cardiac myxomas: localization using a hyaluronate-specific binding protein. | Myxomas are the most common primary tumors of the heart. These lesions contain a gelatinous, ground-substancelike material which has been described as glycosaminoglycan in nature. Using a newly developed, cartilage-derived hyaluronic acid-binding protein and a modification of the avidin-biotin immunostaining procedure,... | ['Adult', 'Carrier Proteins', 'Female', 'Heart Neoplasms', 'Humans', 'Hyaluronan Receptors', 'Hyaluronic Acid', 'Middle Aged', 'Myocardium', 'Myxoma', 'Staining and Labeling'] | 1,710,472 | [['M01.060.116'], ['D12.776.157'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750.281', 'D12.776.543.550.200.625.144', 'D12.776.543.750.705.877.144', 'D23.050.301.350.625.144'], ['D09.698.373.475'], ['M01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bovine undifferentiated alveolar rhabdomyosarcoma and its differentiation in xenotransplanted tumors. | At necropsy, a 7-year-old Holstein cow, clinically diagnosed via rectal palpation as having malignant abdominal neoplasia was found to have many metastatic tumors of various sizes in the abdominal and thoracic cavities and in the liver, lung, kidney, adrenal, uterus, and lymph nodes. These tumors were examined by histo... | ['Abdominal Neoplasms', 'Animals', 'Cattle', 'Cattle Diseases', 'Female', 'Immunohistochemistry', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Microscopy, Electron', 'Neoplasm Transplantation', 'Rhabdomyosarcoma'] | 1,750,169 | [['C04.588.033'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'],... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of the cerebral motor cortex by focal magnetic stimulation: clinical application to neurosurgical patients. | A figure-8 coil was designed that was capable of generating currents over a relatively limited area. In this study, we used the figure-8 coil to localize human cerebral motor cortex by transcranial magnetic stimulation and assessed its value as a diagnostic tool for neurosurgical disease. The subjects were 10 normal vo... | ['Adult', 'Brain Diseases', 'Brain Mapping', 'Brain Neoplasms', 'Electric Stimulation', 'Electromagnetic Fields', 'Female', 'Humans', 'Male', 'Motor Cortex', 'Neurosurgery'] | 7,624,632 | [['M01.060.116'], ['C10.228.140'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.723.402'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.270.548', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Suicides and suicide ideation in the Bible: an empirical survey. | OBJECTIVE: The aim of this review is to summarize all data on suicidal behaviour reported in the Bible and to discuss basic implications for medical ethical positions.METHOD: All books of the Jerusalem Bible, including the apocrypha accepted in the Catholic canon, were searched for all cases of suicide, attempted suici... | ['Bible', 'Empirical Research', 'Humans', 'Suicide', 'Suicide, Attempted', 'Surveys and Questionnaires', 'Theology'] | 16,095,470 | [['K01.517.172'], ['H01.770.644.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.126.980.875', 'I01.880.735.856'], ['F01.145.126.980.875.600', 'I01.880.735.856.600'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['K01.844.949']] | ['Humanities [K]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Occurrence of Trichodina pediculus Ehrenberg, 1838 in Dgal Wielki Lake. | Parasitological investigation were performed in Dgal Wielki, occurrence T. pediculus Ehrenberg 1838 on the roach gills were recorded. On the 277 examined roach in 9 roach specimens T. pediculus were found. Prevalence of roach infection was 3.25%, mean intensity 3.5 and abundance 0.11 parasite per number of fish examine... | ['Animals', 'Ciliophora', 'Cyprinidae', 'Fresh Water', 'Gills', 'Poland', 'Seasons'] | 16,888,950 | [['B01.050'], ['B01.043.185'], ['B01.050.150.900.493.200.244'], ['G16.500.275.280', 'N06.230.232'], ['A13.421'], ['Z01.542.248.679'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Pharmacological overtreatment in epilepsy: mechanisms and management. | Despite considerable advances in the drug treatment of epilepsy in the last decade, pharmacoresistant epilepsy continues to occur today in as many as one in three patients with newly diagnosed epilepsy. These limitations of current drug treatment may result in the inadvertent overtreatment of patients with epilepsy. Ov... | ['Anticonvulsants', 'Contraindications', 'Drug Resistance', 'Drug Therapy, Combination', 'Epilepsy', 'Female', 'Humans', 'Male', 'Maximum Tolerated Dose', 'Risk Factors', 'Treatment Failure'] | 12,445,955 | [['D27.505.954.427.080'], ['E02.208'], ['G07.690.773.984'], ['E02.319.310'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.481', 'G07.690.936.625'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Salinity and Temperature Tolerance of the Nemertean Worm Carcinonemertes errans, an Egg Predator of the Dungeness Crab. | Estuaries can be harsh habitats for the marine animals that enter them, but they may also provide these species with sub-saline refuges from their parasites. The nemertean egg predator Carcinonemertes errans is known to occur less frequently and in smaller numbers on its host, the Dungeness crab Metacarcinus magister, ... | ['Animals', 'Brachyura', 'Invertebrates', 'Larva', 'Salinity', 'Temperature'] | 25,920,719 | [['B01.050'], ['B01.050.500.131.365.190.110'], ['B01.050.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G02.640.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nodulisporic acid opens insect glutamate-gated chloride channels: identification of a new high affinity modulator. | Nodulisporic acid (NA) is an indole diterpene fungal product with insecticidal activity. NA activates a glutamate-gated chloride channel (GluCl) in grasshopper neurons and potentiates channel opening by glutamate. The endectocide ivermectin (IVM) induces a similar, but larger current than NA. Using Drosophila melanogas... | ['Amides', 'Animals', 'Binding Sites', 'Binding, Competitive', 'Caenorhabditis elegans', 'Cell Membrane', 'Chloride Channels', 'Drosophila melanogaster', 'Electrophysiology', 'Grasshoppers', 'Indoles', 'Insecticides', 'Ion Channel Gating', 'Ivermectin', 'Kinetics', 'Molecular Structure', 'Motor Neurons', 'Protein Bindi... | 10,820,028 | [['D02.065'], ['B01.050'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B01.050.500.500.294.400.875.660.250.250'], ['A11.284.149'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['H01.158.344.528',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Swab2know: An HIV-Testing Strategy Using Oral Fluid Samples and Online Communication of Test Results for Men Who Have Sex With Men in Belgium. | BACKGROUND: As HIV remains a public health concern, increased testing among those at risk for HIV acquisition is important. Men who have sex with men (MSM) are the most important group for targeted HIV testing in Europe. Several new strategies have been developed and implemented to increase HIV-testing uptake in this g... | ['Adult', 'Belgium', 'Communication', 'Counseling', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Male', 'Mass Screening', 'Mouth', 'Sexual Partners'] | 26,330,138 | [['M01.060.116'], ['Z01.542.115'], ['F01.145.209', 'L01.143'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.1... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
The effects of preemptive intravenous versus preemptive epidural morphine on postoperative analgesia and surgical stress response after orthopaedic procedures. | BACKGROUND: The purpose of this study was to evaluate the effect of pre-emptive intravenous versus pre-emptive epidural morphine on both postoperative analgesic consumption and surgical stress response.METHODS: Sixty patients, ASA I or II, aged 18-85, undergoing total hip or knee replacement were randomly assigned to t... | ['Adolescent', 'Adult', 'Aged', 'Analgesia, Epidural', 'Analgesics, Opioid', 'Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Middle Aged', 'Morphine', 'Orthopedic Procedures', 'Pain, Postoperative', 'Postoperative Nausea and Vomiting', 'Stress... | 11,070,965 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E03.091.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.10... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells. | The human surfactant protein-A2 (hSP-A2) gene is developmentally regulated, expressed in type II pneumonocytes, and induced by cAMP. cAMP induction of hSP-A2 expression is O2 dependent and mediated by increased phosphorylation, DNA binding, and transcriptional activation of thyroid transcription factor-1 (TTF-1). The T... | ['Cell Line', 'Cyclic AMP', 'Electrophoretic Mobility Shift Assay', 'Gene Expression Regulation', 'Humans', 'I-kappa B Proteins', 'Interleukin-1', 'Lung', 'NF-KappaB Inhibitor alpha', 'NF-kappa B', 'Nuclear Proteins', 'Proline', 'Pulmonary Surfactant-Associated Protein A', 'Reactive Oxygen Species', 'Response Elements'... | 12,040,027 | [['A11.251.210'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['E05.196.401.500'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.365', 'D12.776.260.420', 'D12.776.476.381', 'D12.776.930.326'], ['D12.644.276.374.465.010', 'D12.644.276.37... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pretreatment Serum Amyloid A and C-reactive Protein Comparing with Epstein-Barr Virus DNA as Prognostic Indicators in Patients with Nasopharyngeal Carcinoma: A Prospective Study. | Purpose: The measuring Epstein-Barr virus (EBV) DNA is an important predictor of nasopharyngeal carcinoma (NPC). This study evaluated the predictive value of pretreatment serum amyloid A (SAA) and C-reactive protein (CRP) comparing with EBV DNA in patients with NPC.Materials and Methods: In an observational study of 41... | ['Adult', 'Aged', 'Aged, 80 and over', 'C-Reactive Protein', 'Carcinoma', 'DNA, Viral', 'Epstein-Barr Virus Infections', 'Female', 'Herpesvirus 4, Human', 'Humans', 'Male', 'Middle Aged', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Neoplasm Staging', 'Prognosis', 'Prospective Studies', 'Serum Amyloid A Pro... | 28,707,462 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C04.557.470.200'], ['D13.444.308.568'], ['C01.925.256.466.313', 'C01.925.928.313'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor. | The first structural and biophysical data on the folate biosynthesis pathway enzyme and drug target, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (SaHPPK), from the pathogen Staphylococcus aureus is presented. HPPK is the second essential enzyme in the pathway catalysing the pyrophosphoryl transfer from cofactor... | ['Bacterial Proteins', 'Diphosphotransferases', 'Magnetic Resonance Spectroscopy', 'Pterins', 'Staphylococcus aureus'] | 22,276,115 | [['D12.776.097'], ['D08.811.913.696.175'], ['E05.196.867.519'], ['D03.633.100.733.631', 'D23.767.831'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Physical signs and lung function tests in patients with chronic obstructive pulmonary disease (COPD)]. | We examined 40 consecutive patients with chronic obstructive pulmonary disease (COPD) admitted to our institute between April and September 1985 for acute exacerbation, when they recovered from acute exacerbation and became cooperative to undergo lung function tests. Additionally, a follow up study was also done 4 year... | ['Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Lung', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Prognosis', 'Respiratory Function Tests'] | 2,366,387 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381.495'], ['M01.060.116.630'], ['E01.789'], ['E01.370.386.700']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of genetic loci associated with fire blight resistance in Malus through combined use of QTL and association mapping. | Fire blight, incited by the enterobacterium Erwinia amylovora, is a destructive disease of Rosaceae, particularly of apples and pears. There are reports on the molecular mechanisms underlying E. amylovora pathogenesis and how the host activates its resistance mechanism. The host's resistance mechanism is quantitatively... | ['Chromosome Mapping', 'Crosses, Genetic', 'Disease Resistance', 'Erwinia amylovora', 'Genome-Wide Association Study', 'Malus', 'Plant Diseases', 'Plant Shoots', 'Polymorphism, Single Nucleotide', 'Quantitative Trait Loci'] | 23,627,651 | [['E05.393.183'], ['E05.393.281'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['B03.440.450.425.300.050', 'B03.660.250.150.175.050'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.65... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of an oxygen-dependent inducible promoter, the nar promoter of Escherichia coli, to utilize in metabolic engineering. | The nar promoters, whose transcription is maximally induced under microaerobic conditions in the presence of nitrate ion, were characterized in fed-batch culture to determine whether they can be used for metabolic engineering, by which overall production of valuable chemicals can be increased. For this purpose, we test... | ['Chromosomes, Bacterial', 'DNA, Bacterial', 'Escherichia coli', 'Fermentation', 'Gene Expression Regulation, Bacterial', 'Genetic Engineering', 'Ions', 'Lac Operon', 'Mutation', 'Oxygen', 'Promoter Regions, Genetic'] | 11,460,248 | [['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.158.249', 'G03.191.249'], ['G05.308.300'], ['E05.393.420'], ['D01.248.497'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['G05.365.590'], ['D01.268.185.550', 'D01.36... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of combined physical and cognitive training on fitness and neuropsychological outcomes in healthy older adults. | PURPOSE: Physical exercise and cognitive training have been shown to enhance cognition among older adults. However, few studies have looked at the potential synergetic effects of combining physical and cognitive training in a single study. Prior trials on combined training have led to interesting yet equivocal results.... | ['Aged', 'Aged, 80 and over', 'Cognition', 'Exercise Therapy', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Physical Fitness', 'Resistance Training'] | 27,698,558 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F02.463.188'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['E02.760.169.063.500.387.875', 'E02.779.483.875', 'E02.831.535.483.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Troponin I Levels in Asymptomatic Hemodialysis Patients. | BACKGROUND: End-stage renal disease (ESRD) represents a situation in which persistently elevated levels of cardiac troponins I (cTnI) are frequently found in the absence of clinically evident cardiac disease. Moreover, the effect of hemodialysis (HD) on cTnI levels is not definitively elucidated. The aim of this study ... | ['Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Time Factors', 'Troponin I'] | 28,957,803 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E02.870.300', 'E02.912.800'], ['G01.910.857'], ['D05.500.945.925', 'D05.750.078.730.825.925', 'D12.776.210.500.910.925', 'D12.776.220.525.825... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of spinach chloroplast F0F1 by an Fe2+/ascorbate/H2O2 system. | Plant chloroplasts are particularly threatened by free radical attack. We incubated purified soluble spinach chloroplast F(0)F(1) (CF(0)F(1), EC 3.6.3.34) with an Fe(2+)/H(2)O(2)/ascorbate system, and about 60% inactivation of the ATPase activity was reached after 60 min. Inactivation was not prevented by omission of H... | ['Ascorbic Acid', 'Chloroplast Proton-Translocating ATPases', 'Deferoxamine', 'Dithiothreitol', 'Edetic Acid', 'Electrophoresis, Polyacrylamide Gel', 'Free Radicals', 'Hydrogen Peroxide', 'Hydrogen-Ion Concentration', 'Kinetics', 'Oxidation-Reduction', 'Recombinant Proteins', 'Spinacia oleracea'] | 17,870,588 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D08.811.277.040.025.325.500', 'D08.811.913.696.650.150.500.500', 'D12.776.157.530.450.250.875.500.500', 'D12.776.543.585.450.250.875.500.500', 'D12.776.543.930.249', 'D12.776.765.199.750.374'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['D02.033.80... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Talking or Keeping Silent About Parental Mental Health Problems-A Grounded Theory of Parents' Decision Making and Experiences with Their Children. | This grounded theory study explored parents' experiences of responding to their children's need for understanding parental mental health concerns. Fifteen parents with severe and enduring mental health difficulties participated in the study. The findings suggest four main social processes that influence parents' talk w... | ['Adolescent', 'Adult', 'Child', 'Child of Impaired Parents', 'Child, Preschool', 'Female', 'Grounded Theory', 'Humans', 'Male', 'Mental Disorders', 'Parent-Child Relations', 'Qualitative Research'] | 27,292,374 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.106'], ['M01.060.406.448'], ['H01.770.644.241.424'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F01.829.263.370.290'], ['H01.770.644.241.850']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Middle ear microbiome differences in indigenous Filipinos with chronic otitis media due to a duplication in the A2ML1 gene. | BACKGROUND: Previously rare A2ML1 variants were identified to confer otitis media susceptibility in an indigenous Filipino community and in otitis-prone US children. The goal of this study is to describe differences in the middle ear microbiome between carriers and non-carriers of an A2ML1 duplication variant that incr... | ['Adolescent', 'Child', 'Child, Preschool', 'DNA, Bacterial', 'Ear, Middle', 'Female', 'Genes, Duplicate', 'Humans', 'Male', 'Microbiota', 'Otitis Media', 'Philippines', 'Population Groups', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Young Adult', 'alpha-Macroglobulins'] | 27,799,062 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['D13.444.308.212'], ['A09.246.397'], ['G05.360.340.024.340.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['C09.218.705.663'], ['Z01.252.145.671', 'Z01.639.790'], ['M01.686', 'N01.224... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Molecular and genetical analysis of the fructose-glucose transport system in the cyanobacterium Synechocystis PCC6803. | Complementation for glucose transport capacity of deficient mutants from Synechocystis PCC6803 allowed the cloning of the corresponding gene, glcP. The protein predicted from one open reading frame (ORF) in the DNA sequence was 468 residues long. It showed 46-60% amino acid sequence homology and similarity in size and ... | ['Amino Acid Sequence', 'Base Sequence', 'Chromosomes', 'Cloning, Molecular', 'Cyanobacteria', 'Fructose', 'Gene Library', 'Glucose', 'Molecular Sequence Data', 'Monosaccharide Transport Proteins', 'Mutation', 'Phenotype', 'Plasmids', 'Restriction Mapping', 'Sequence Homology, Nucleic Acid', 'Transformation, Genetic'] | 2,507,869 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['E05.393.220'], ['B03.280', 'B03.440.475.100'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['G05.360.325'], ['D09.947.875.359.448'], ['L01.453.245.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Purification of nitrogen regulator II, the product of the glnL (ntrB) gene of Escherichia coli. | We purified the product of glnL (ntrB), NRII, and the product of a mutant glnL allele, NRII2302. In vitro transcription of the nitrogen-regulated promoter glnAp2 by purified components of Escherichia coli required NRII or NRII2302 when the template DNA was linear. | ['Escherichia coli', 'Genes, Bacterial', 'Genes, Regulator', 'Nitrogen'] | 3,536,843 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.425'], ['D01.268.604', 'D01.362.625']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibacterial and antifungal activities of some Mexican medicinal plants. | In Mexico about 4,000 plant species have some medicinal use. The aim of this work was to evaluate the antimicrobial activity of six Mexican medicinal plants against fungi and Gram-positive and Gram-negative bacteria. Methanolic extracts were prepared from the Mexican medicinal plants Amphypteringium adstrigens, Castell... | ['Anti-Bacterial Agents', 'Antifungal Agents', 'Bacteria', 'Fungi', 'Mexico', 'Microbial Sensitivity Tests', 'Plant Extracts', 'Plants, Medicinal'] | 20,041,800 | [['D27.505.954.122.085'], ['D27.505.954.122.136'], ['B03'], ['B01.300'], ['Z01.107.567.589'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D20.215.784.500', 'D26.667'], ['B01.650.560']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Reasons for the use of mild analgesics among English students. | OBJECTIVE: Mild analgesics such as paracetamol and ibuprofen are amongst the most commonly used over-the-counter (OTC) drugs. However, little is known about what beliefs people hold about them. The present paper examines: (a) the patterns of mild analgesic usage in a sample of university students, (b) their beliefs abo... | ['Acetaminophen', 'Analgesics, Non-Narcotic', 'Anti-Inflammatory Agents, Non-Steroidal', 'Aspirin', 'Citrates', 'Cross-Sectional Studies', 'Drug Combinations', 'England', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Ibuprofen', 'Male', 'Nonprescription Drugs', 'Risk', 'Self Medication', 'Sodium Bicarbo... | 17,657,580 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389.657.410.595.176'], ['D02.241.081.901.434'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.85... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, In... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Purification and characterization of a mitogen-activated protein kinase tyrosine phosphatase from Xenopus eggs. | The mitogen-activated protein (MAP) kinases are serine-threonine protein kinases that are activated by tyrosine and threonine phosphorylation by the dual specificity protein kinase MEK (MAP kinase/ERK kinase). The present report describes the purification to near homogeneity and characterization of a protein tyrosine p... | ['Animals', 'Chromatography, Affinity', 'Chromatography, Gel', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme Activation', 'MAP Kinase Kinase 1', 'Mitogen-Activated Protein Kinase Kinases', 'Oocytes', 'Phosphorylation', 'Protein-Serine-Threonine Kinases', 'Protein-Tyrosine Kinas... | 8,227,071 | [['B01.050'], ['E05.196.181.400.170'], ['E05.196.181.400.250'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.263', 'G03.328'], ['D08.811.913.696.620.682.700.565.100', 'D08.811.913.696.620.682.725.200.100', 'D12.644.360.440.100', 'D12.776.476.440.100'], ['D08.811.913.696.620.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Charcoal-column haemoperfusion does not significantly enhance chlormethiazole removal. | A 26-year-old man had convulsions after taking an overdose of slow-release aminophylline tablets. The convulsions were treated with an infusion of chlormethiazole and theophylline was removed by charcoal-column haemoperfusion. It has been suggested that haemoperfusion might be useful for removing chlormethiazole and th... | ['Adult', 'Charcoal', 'Chlormethiazole', 'Hemoperfusion', 'Humans', 'Male'] | 3,804,351 | [['M01.060.116'], ['D01.268.150.150'], ['D02.886.675.180', 'D03.383.129.708.180'], ['E02.870.244', 'E02.912.430', 'E04.292.510'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The rat biliary and urinary metabolism of the N6-methylated derivative of elliptinium acetate, and antitumor agent. | The rat biliary and urinary metabolism of N2,N6-dimethyl-9-hydroxyellipticinium (an N6-methyl derivative of elliptinium acetate, an antitumor agent) is reported. Two main metabolites have been identified: the glucuronide and sulfate derivatives by conjugation of the hydroxy group at position 9. Excretion profiles in bi... | ['Alkaloids', 'Animals', 'Antineoplastic Agents', 'Bile', 'Biotransformation', 'Chemical Phenomena', 'Chemistry, Physical', 'Chromatography, High Pressure Liquid', 'Ellipticines', 'Glutathione', 'Male', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 2,898,353 | [['D03.132'], ['B01.050'], ['D27.505.954.248'], ['A12.200.087'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['G02'], ['H01.181.529'], ['E05.196.181.400.300'], ['D03.132.436.681.333', 'D03.633.100.473.144.249', 'D03.633.100.473.402.681.333', 'D03.633.100.496.500.500.681.333', 'D03.633.300.148.249'], ['D12.644.456.44... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Apparent mass of the standing human body when using a whole-body vibration training machine: Effect of knee angle and input frequency. | Several studies have investigated the transmission of vibration from the vibrating plate of a whole-body vibration training machine (WBVTM) to different locations on the human body. No known work has investigated the interface force between the vibrating plate of the machine and the human body. This paper investigates ... | ['Acceleration', 'Adolescent', 'Adult', 'Biomechanical Phenomena', 'Humans', 'Knee', 'Male', 'Standing Position', 'Surface Tension', 'Vibration', 'Young Adult'] | 30,466,950 | [['G01.482.107'], ['M01.060.057'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['G11.427.695.600'], ['G02.860.816'], ['G01.374.930'], ['M01.060.116.815']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
High-performance liquid chromatography-mass spectrometry in the clinical laboratory. | The development of HPLC-atmospheric pressure ionization-mass spectrometry (HPLC-MS) has presented clinical laboratories with a powerful analytic tool. The aim of this paper is to provide an overview of the current status of HPLC-MS in the clinical laboratory; to discuss the challenges to mass spectrometry in this setti... | ['Chromatography, High Pressure Liquid', 'Clinical Laboratory Techniques', 'Mass Spectrometry'] | 16,404,795 | [['E05.196.181.400.300'], ['E01.370.225', 'E05.200'], ['E05.196.566']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The accumulation of phytoalexin in cucumber plant after stress. | During the course of pathogens penetrating the plant cell, besides of chemical secretion, the pathogens may cause mechanical signal by the physical pressure on the plant cell. In the current study, we use the pressure as the stress signal to study the induction in plant resistance and the effect of accumulation of phyt... | ['Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Cladosporium', 'Cucumis sativus', 'Indicators and Reagents', 'Physical Stimulation', 'Plant Diseases', 'Plant Extracts', 'Plant Leaves', 'Sesquiterpenes', 'Spectrophotometry, Ultraviolet', 'Stress, Mechanical', 'Terpenes'] | 15,979,288 | [['E05.196.181.400.300'], ['E05.196.181.400.537'], ['B01.300.381.200'], ['B01.650.940.800.575.912.250.300.188.666'], ['D27.720.470.410'], ['E05.723'], ['G15.610'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['D02.455.849.765'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G01.374.835'], ['D02.455.849']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stabilization of lysozyme-incorporated polyion complex micelles by the omega-end derivatization of poly(ethylene glycol)-poly(alpha,beta-aspartic acid) block copolymers with hydrophobic groups. | To improve the stability of lysozyme-incorporated polyion complex (PIC) micelles in physiological condition, three types of hydrophobic groups, including phenyl (Phe), naphthyl (Nap), and pyrenyl (Py) terminal groups, were separately introduced to the omega-end of poly(ethylene glycol)-poly(alpha,beta-aspartic acid) bl... | ['Aspartic Acid', 'Hydrophobic and Hydrophilic Interactions', 'Ions', 'Micelles', 'Muramidase', 'Polyethylene Glycols', 'Polymers'] | 15,779,933 | [['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['G02.409'], ['D01.248.497'], ['D05.374', 'D26.255.560'], ['D08.811.277.450.642'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Goniometer not better than unaided visual inspection at estimating ventral penile curvature on plastic models. | INTRODUCTION AND OBJECTIVE: The assessment of penile curvature is a key component of hypospadias surgery, as it often determines if a one- or two-stage procedure should be performed. The objective of this study was to compare unaided visual inspection (UVI) against goniometry estimations of ventral penile curvature (VC... | ['Adult', 'Humans', 'Male', 'Models, Anatomic', 'Penis', 'Plastics', 'Urologists', 'Visual Perception'] | 31,680,019 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['A05.360.444.492'], ['D05.750.716', 'D25.720.716', 'J01.637.051.720.716'], ['M01.526.485.810.955', 'N02.360.810.955'], ['F02.463.593.932']] | ['Named Groups [M]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Does binding of Gd-DTPA to myocardial tissue contribute to late enhancement in a model of acute myocardial infarction? | The long-lasting signal enhancement by Gd-DTPA in areas of myocardial infarction has been conventionally explained by low perfusion and an enhanced Gd distribution volume. To test whether binding of Gd to myocardial constituents is an additional factor contributing to this effect, Gd-DTPA was allowed to equilibrate bet... | ['Animals', 'Contrast Media', 'Gadolinium DTPA', 'Image Enhancement', 'In Vitro Techniques', 'Magnetic Resonance Imaging', 'Myocardial Infarction', 'Myocardium', 'Swine'] | 12,509,833 | [['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E05.481'], ['E01.370.350.825.500'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['A02.633.580', 'A07.541.704', 'A10... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Palmitate induces COX-2 expression via the sphingolipid pathway-mediated activation of NF-êB, p38, and ERK in human dermal fibroblasts. | It has been suggested that free fatty acids (FFA) such as palmitate, which are secreted from enlarged adipocytes in the subcutaneous fat of obese subjects, serve as a link between obesity and altered skin functions. Cyclooxygenease-2 (COX-2) and prostanoids participate in the induction of impaired dermal function. In t... | ['Cells, Cultured', 'Ceramides', 'Coenzyme A Ligases', 'Cyclooxygenase 2', 'Dinoprostone', 'Enzyme Inhibitors', 'Extracellular Signal-Regulated MAP Kinases', 'Fibroblasts', 'Humans', 'NF-kappa B', 'Obesity', 'Palmitates', 'Sphingolipids', 'Triazenes', 'p38 Mitogen-Activated Protein Kinases'] | 24,337,700 | [['A11.251'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['D08.811.464.267.500'], ['D08.811.600.720.750'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D27.505.519.389'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.4... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stimulation of spermatogenesis in stalk-sectioned rhesus monkeys by testosterone alone. | Testosterone alone stimulated spermatogenesis in four adult, pituitary stalk-sectioned rhesus monkeys. Ten to 14 weeks after transection of the pituitary stalk, testicular volumes declined to about one fifth of the presurgical values. Serum LH levels declined precipitously, being undetectable 1 week postsurgery, and se... | ['Animals', 'Estradiol', 'Hypophysectomy', 'Luteinizing Hormone', 'Macaca mulatta', 'Male', 'Prolactin', 'Radioimmunoassay', 'Sperm Count', 'Spermatogenesis', 'Testis', 'Testosterone'] | 6,853,673 | [['B01.050'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E04.270.532', 'E04.525.400'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['D06.472.699.322.576.773', 'D06.472.699.631.525.525', 'D12.644.548.69... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Atypical Prader-Willi and 15q13.3 Microdeletion Syndromes in a Patient with an Unbalanced Translocation. | Prader-Willi syndrome (PWS) and recurrent 15q13.3 microdeletion syndrome can be caused by genomic rearrangements in the complex 15q11q13 chromosomal region. Here, we describe the first female child with PWS and 15q13.3 microdeletion syndrome resulting from an unusual 10.7-Mb deletion from 15pter to 15q13.3 due to an un... | ['Child, Preschool', 'Chromosome Deletion', 'Chromosome Disorders', 'Chromosomes, Human, Pair 15', 'Female', 'Humans', 'Infant, Newborn', 'Intellectual Disability', 'Prader-Willi Syndrome', 'Seizures', 'Translocation, Genetic'] | 31,394,532 | [['M01.060.406.448'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['C16.131.260', 'C16.320.180'], ['A11.284.187.520.300.370.385', 'G05.360.162.520.300.370.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cetacean strandings in Costa Rica (1966-1999). | Cetacean strandings in Costa Rica are reported for a period of 33 years, with a total of 35 strandings, 13 species and 247 individuals involved. The vast majority of documented strandings occurred on the Pacific coast and correspond to single individuals (32 and 28 strandings respectively). The highest stranding number... | ['Animals', 'Cetacea', 'Costa Rica', 'Environmental Monitoring', 'Marine Biology'] | 11,935,918 | [['B01.050'], ['B01.050.150.900.649.313.875'], ['Z01.107.169.238'], ['N06.850.460.350.080', 'N06.850.780.375'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Bradykinin stimulates phosphoinositide turnover and phospholipase C but not phospholipase D and NADPH oxidase in human neutrophils. | In response to formyl-Met-Leu-Phe (fMLP), human neutrophils (PMN) generate superoxide anion (O2-) by the enzyme complex NADPH oxidase. The modulation of phosphoinositide (PPI) turnover and the activation of phospholipases C (PLC) and D (PLD) have been shown to be early steps in the oxidative response of fMLP-stimulated... | ['Amino Acid Sequence', 'Bradykinin', 'Enzyme Activation', 'Enzyme Inhibitors', 'Humans', 'Molecular Sequence Data', 'N-Formylmethionine Leucyl-Phenylalanine', 'NADH, NADPH Oxidoreductases', 'NADPH Oxidases', 'Neutrophils', 'Nitric Oxide', 'Phosphatidylinositols', 'Phospholipase D', 'Protein Kinase C', 'Stimulation, Ch... | 8,613,709 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D02... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Clinical results of treatment of postsurgical endotoxin-mediated sepsis with polymyxin-B direct hemoperfusion. | We evaluated the possibility of preventing the evolution of endotoxin-mediated sepsis in severe septic shock using early treatment of critical endotoxemia with polymyxin-B direct hemoperfusion (PMX-DHP). Thirty-eight postsurgical patients who fulfilled at least 2 criteria for systemic inflammatory response syndrome wer... | ['Adult', 'Aged', 'Bacterial Infections', 'Blood Pressure', 'Endotoxins', 'Female', 'Heart Rate', 'Hemoperfusion', 'Humans', 'Kidney Transplantation', 'Liver Transplantation', 'Male', 'Middle Aged', 'Polymyxin B', 'Postoperative Complications', 'Sepsis'] | 20,534,214 | [['M01.060.116'], ['M01.060.116.100'], ['C01.150.252'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D23.946.123.329'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E02.870.244', 'E02.912.430', 'E04.292.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hydrolyzed milk-serum peptides reduce body weight and fat content of dietary obese rats ameliorating their antioxidant status and liver functions. | AIM: Recent studies suggested that weight reduction under energy restriction required protein supplementation. Moreover, a significant decrease in serum cholesterol and triglycerides was observed when milk-serum proteins and, in particular, their hydrolyzed peptides were compared to milk casein.METHODS: Six Sprague-Daw... | ['Animals', 'Antioxidants', 'Body Weight', 'Cholesterol', 'Liver', 'Milk Proteins', 'Obesity', 'Rats', 'Rats, Sprague-Dawley', 'Triglycerides'] | 16,210,997 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['A03.620'], ['A12.790.520', 'D12.776.256.159.750',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Cytokine stimulation of human fetal hematopoietic cells. | The effects of interleukins 3 and 6, stem cell factor, and granulocyte-macrophage colony-stimulating factor on human fetal hematopoietic, bone marrow, and cord blood cells were studied on the basis of the colony-forming capacity. Fetal hematopoietic cells from 28 elective abortions, three bone marrow samples, and three... | ['Bone Marrow Cells', 'Cell Division', 'Cytokines', 'Erythroid Precursor Cells', 'Female', 'Fetal Blood', 'Fetus', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Granulocytes', 'Hematopoietic Stem Cells', 'Humans', 'Interleukin-3', 'Interleukin-6', 'Kinetics', 'Macrophages', 'Megakaryocytes', 'Pregnancy', 'Stem C... | 8,894,626 | [['A11.148', 'A15.378.316'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.148.378.590.837.250', 'A11.443.240.497', 'A11.872.378.590.817.250', 'A15.378.316.378.590.837.250'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['A16... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stimulation by histamine of TPA-dependent hepatocyte growth factor production in promyelocytic leukemia HL-60 cells. | Hepatocyte growth factor (HGF) is most likely a physiological hepatotrophic factor that triggers regeneration of the injured liver. Histamine may also be important in the pathophysiology of the injured liver. Previously we showed that histamine production was increased in liver macrophages of mice injected with CCI4, a... | ['Dose-Response Relationship, Drug', 'Enzyme-Linked Immunosorbent Assay', 'HL-60 Cells', 'Hepatocyte Growth Factor', 'Histamine', 'Histamine H2 Antagonists', 'Humans', 'Ranitidine', 'Tetradecanoylphorbol Acetate'] | 9,720,223 | [['G07.690.773.875', 'G07.690.936.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['D02.092.211.215.501', ... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seventy-two hour infusions of LHRH in normal men: gonadotropin and testicular steroid responses. | Four normal male subjects received LHRH by continuous infusion for 72 hrs at 1.4 microgram/min. Mean basal LH was 7.7 +/- 1.0 mIU/ml, increased to a maximum of 120 +/- 22.7 mIU/ml, and then declined to levels between 28--34 mIU/ml for the last 30 hrs of infusion; FSH rose from 3.7 to 11.4 mIU/ml (p less than 0.05) at 1... | ['17-alpha-Hydroxypregnenolone', 'Adult', 'Androgens', 'Androstenedione', 'Dehydroepiandrosterone', 'Estradiol', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Gonadotropins, Pituitary', 'Humans', 'Luteinizing Hormone', 'Male', 'Progesterone', 'Progestins', 'Testosterone'] | 156,193 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway. | Sphingosine kinase phosphorylates sphingosine to generate sphingosine 1-phosphate, a phospholipid that has been implicated in signaling by a number of transmembrane receptors and was recently shown to act as a ligand for a specific class of G protein-coupled receptors. Here we show that the G protein-coupled bradykinin... | ['Enzyme Activation', 'Enzyme Inhibitors', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Lysophospholipids', 'Mitogen-Activated Protein Kinases', 'Phosphotransferases (Alcohol Group Acceptor)', 'Receptor, Bradykinin B2', 'Receptors, Bradykinin', 'Signal Transduction', 'Sphingosine'] | 11,258,664 | [['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.755.375.760.550'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['D08.811.913.696.620'], ['D12.776.543.750.695.080.500', 'D12.776.543.750.720.600.220.500', 'D12.776... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of extremely-low-frequency pulsed electromagnetic fields on collagen synthesis in rat skin. | To investigate the effects of extremely-low-frequency PEMFs (pulsed electromagnetic fields) on the synthesis of epidermal collagen, six groups of animals each consisting of eight mature male rats were selected randomly: one group for the control and five for the test. Using a parallel set of Helmholtz coils, a uniform ... | ['Animals', 'Collagen', 'Electromagnetic Fields', 'Epidermis', 'Hydroxyproline', 'Male', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Skin'] | 16,162,095 | [['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.358.500.260', 'G01.358.750.500'], ['A10.272.497', 'A17.815.250'], ['D12.125.072.401.623.478'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Psychological factors in retrograde amnesia: self-deception and a broken heart. | We explored potential contributing psychological factors in a patient ('XF') with focal retrograde amnesia, within the framework proposed by Kopelman (2000, Cognitive Neuropsychology, 17, 585). In particular, we investigated the psychological trait of self-enhancement. We constructed a self-report questionnaire measure... | ['Adult', 'Amnesia, Retrograde', 'Humans', 'Male', 'Neuropsychological Tests', 'Self Concept', 'Stress, Psychological', 'Surveys and Questionnaires'] | 18,825,573 | [['M01.060.116'], ['C10.597.606.525.100.150', 'C23.888.592.604.529.100.150', 'F01.700.625.100.150', 'F03.615.200.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F01.752.747.792'], ['F01.145.126.990', 'F02.830.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pattern of presynaptic nerve activity can determine the type of neurotransmitter regulating a postsynaptic event. | The mammalian superior cervical ganglion has been the classical preparation for studying cholinergic transmission between neurones. Recently, however, evidence has been presented showing that, in addition to the postsynaptic changes mediated via nicotinic and muscarinic receptors, there is a non-cholinergic component t... | ['Animals', 'Dihydroxyphenylalanine', 'Electric Stimulation', 'Ganglia, Sympathetic', 'Male', 'Parasympatholytics', 'Physostigmine', 'Rats', 'Rats, Inbred Strains', 'Synapses', 'Time Factors', 'Tyrosine 3-Monooxygenase'] | 6,148,705 | [['B01.050'], ['D02.092.311.200', 'D02.455.426.559.389.657.166.175.200', 'D12.125.072.050.685.400', 'D12.125.072.050.875.130'], ['E05.723.402'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800.300'], ['D27.505.696.663.050.650'], ['D02.241.081.251.583.682', 'D03.132.436.545', 'D03.633.100.473.402.545', 'D03.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Describing partially unfolded states of proteins from sparse NMR data. | Proteins involved in signal transduction can usually be present in two states: an inactive and an active (signaling) state. In the case of photoreceptors such as PYP, it has been shown that the signaling state has a large degree of structural and dynamic disorder. Conventional structural NMR approaches present difficul... | ['Bacterial Proteins', 'Muramidase', 'Mutation', 'Nuclear Magnetic Resonance, Biomolecular', 'Photoreceptors, Microbial', 'Protein Denaturation', 'Protein Folding', 'Protein Structure, Tertiary'] | 16,331,422 | [['D12.776.097'], ['D08.811.277.450.642'], ['G05.365.590'], ['E05.196.867.519.550'], ['D12.776.752'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.610']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Myocardial perfusion in coronary disease: thallium-201 planar scintigraphy]. | This research evaluated the diagnostic and analytic effectiveness of 201-thallium imaging in a group of patients with coronary artery disease, each one of them with different localization, extent and number of coronary vessel obstructions. The thallium-201 imaging was performed immediately after ergometric test and rep... | ['Adult', 'Aged', 'Coronary Circulation', 'Coronary Disease', 'Electrocardiography', 'Exercise Test', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radionuclide Imaging', 'Thallium Radioisotopes'] | 2,747,943 | [['M01.060.116'], ['M01.060.116.100'], ['G09.330.100.324'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.710', 'E01.370.384.730'], ['D... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Seasonality of diarrhetic shellfish poisoning at a coastal lagoon in Portugal: rainfall patterns and folk wisdom. | Of the three types of toxicity known so far in Portuguese shellfish, only diarrhetic shellfish poisoning (DSP) and amnesic shellfish poisoning (ASP) are produced by microalgae that seem to have been present in the last decades or centuries. The most important paralytic shellfish poisoning (PSP) producer, Gymnodinium ca... | ['Animals', 'Bivalvia', 'Ciguatera Poisoning', 'Diarrhea', 'Folklore', 'Marine Toxins', 'Portugal', 'Rain', 'Retrospective Studies', 'Seasons', 'Shellfish', 'Shellfish Poisoning'] | 12,565,738 | [['B01.050'], ['B01.050.500.644.080'], ['C25.723.415.246'], ['C23.888.821.214'], ['I01.076.201.450.515', 'K01.517.455'], ['D23.946.580'], ['Z01.542.727'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750... | ['Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agricul... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Implications of deep electrode insertion on cochlear implant fitting. | Using long Med-El Combi40+ electrode arrays, it is now possible to cover the whole range of the cochlea, up to about two turns. Such insertion depths have received little attention. To evaluate the contribution of deeply inserted electrodes, five Med-El cochlear implant users were tested on vowel and consonant identifi... | ['Adult', 'Cochlear Implantation', 'Cochlear Implants', 'Deafness', 'Electrodes, Implanted', 'Humans', 'Loudness Perception', 'Middle Aged', 'Pitch Perception', 'Radiography', 'Speech Perception'] | 17,216,585 | [['M01.060.116'], ['E04.580.450.220', 'E04.650.220'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['E07.305.250.319', 'E07.695.202'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products. | There is mounting evidence that MHC class I peptide ligands are predominantly generated from defective ribosomal products and other classes of polypeptides degraded rapidly (t1/2 < 10 min) following their synthesis. The most direct evidence supporting this conclusion is the rapid inhibition of peptide ligand generation... | ['Animals', 'Antigen Presentation', 'Antigens, Ly', 'Cell Line, Tumor', 'Cycloheximide', 'Egg Proteins', 'Green Fluorescent Proteins', 'H-2 Antigens', 'L Cells', 'Ligands', 'Membrane Proteins', 'Mice', 'Nucleoproteins', 'Ovalbumin', 'Peptide Biosynthesis', 'Peptide Fragments', 'Peptides', 'Proteasome Endopeptidase Comp... | 16,785,518 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D23.050.301.264.920', 'D23.101.100.920'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.383.621.808.240'], ['D12.776.290'], ['D12.776.532.265'], ['D23.050.301.500.100.350', 'D23.050.301.500.400.199', 'D23.050.705.552.100.350', 'D23.050.705.552.410.199'], ['A11.251.210... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative imaging reveals real-time Pou5f3-Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish. | Formation of the three embryonic germ layers is a fundamental developmental process that initiates differentiation. How the zebrafish pluripotency factor Pou5f3 (homologous to mammalian Oct4) drives lineage commitment is unclear. Here, we introduce fluorescence lifetime imaging microscopy and fluorescence correlation s... | ['Animals', 'Intravital Microscopy', 'Mesoderm', 'Microscopy, Fluorescence', 'Nanog Homeobox Protein', 'Octamer Transcription Factor-3', 'Protein Binding', 'Spatio-Temporal Analysis', 'Spectrometry, Fluorescence', 'Zebrafish', 'Zebrafish Proteins'] | 27,684,073 | [['B01.050'], ['E01.370.350.515.277', 'E05.595.185'], ['A16.504.660'], ['E01.370.350.515.458', 'E05.595.458'], ['D12.776.260.400.530', 'D12.776.930.542'], ['D12.776.260.655.500.300', 'D12.776.930.710.500.300'], ['G02.111.679', 'G03.808'], ['E05.318.740.933.500', 'N05.715.360.750.746.500', 'N06.850.520.830.933.500'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Germ cell tumors of the ovary-lymph node metastases. | There is a controversy concerning the value of second look surgery and lymph node sampling for patients with germ cell tumors of the ovary. A patient is presented with endodermal sinus tumor in a mixed germ cell tumor of the ovary. The elevated serum alpha-fetoprotein (AFP) became normal. At second look surgery microsc... | ['Adult', 'Female', 'Humans', 'Lymphatic Metastasis', 'Neoplasms, Germ Cell and Embryonal', 'Ovarian Neoplasms', 'Reoperation', 'alpha-Fetoproteins'] | 2,417,919 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['C04.557.465'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E04.690'], ['D12.776.124.790.106.092', 'D12.776.320.525.500', 'D12.776.377.228.500', ... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cutaneous malignancies in Indigenous Peoples of urban Sydney. | INTRODUCTION: Despite 3% of Australians identifying as Indigenous, cutaneous malignancies in these patients, including incidence, risk factors and outcomes have not been investigated. This is despite recognition that cancer outcomes in this population are significantly poorer.METHODS: We undertook a retrospective case ... | ['Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'New South Wales', 'Oceanic Ancestry Group', 'Retrospective Studies', 'Risk Factors', 'Skin Neoplasms'] | 30,447,047 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['M01.686.508.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.50... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Diagnostic Accuracy of APRI, AAR, FIB-4, FI, and King Scores for Diagnosis of Esophageal Varices in Liver Cirrhosis: A Retrospective Study. | BACKGROUND Aspartate aminotransferase-to-platelet ratio index (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), FIB-4, fibrosis index (FI), and King scores might be alternatives to the use of upper gastrointestinal endoscopy for the diagnosis of esophageal varices (EVs) in liver cirrhosis. Thi... | ['Adult', 'Esophageal and Gastric Varices', 'Female', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Retrospective Studies'] | 26,687,574 | [['M01.060.116'], ['C06.405.117.240', 'C06.552.494.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of Echinococcus multilocularis and other foodborne parasites in fox, cat and dog faeces collected in kitchen gardens in a highly endemic area for alveolar echinococcosis. | Echinococcus multilocularis, Toxoplasma gondii and Toxocara spp. are foodborne parasites whose eggs or oocysts are spread in the environment via canid or felid faeces. They can cause infections in humans following the raw consumption of contaminated fruit or vegetables. In this study, their occurrence was investigated ... | ['Animals', 'Cat Diseases', 'Cats', 'Dog Diseases', 'Dogs', 'Echinococcosis', 'Echinococcosis, Hepatic', 'Echinococcus multilocularis', 'Endemic Diseases', 'Feces', 'Foxes', 'France', 'Gardens', 'Real-Time Polymerase Chain Reaction', 'Toxocara', 'Toxoplasma'] | 28,748,783 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C01.610.335.190.396'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['B01.050.500.500.736.215.327.500'], ['N06.850.392'], ['A12.459'], ['B01.050.150.900.649.313.7... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
An equity analysis of health examination service utilization by women from underdeveloped areas in western China. | OBJECTIVE: This study sought to examine the sources of inequity in health examination service utilization by women from underdeveloped areas in western China.METHODS: Based on data from the 5th National Health Service Survey in Shaanxi province, women's utilization of health examination services was examined according ... | ['Adolescent', 'Adult', 'China', 'Female', 'Healthcare Disparities', 'Humans', 'Medically Underserved Area', 'Middle Aged', 'Papanicolaou Test', 'Physical Examination', "Women's Health Services", 'Young Adult'] | 29,065,129 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.474.164'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.650.340', 'N05.300.450.520'], ['M01.060.116.630'], ['E01.370.225.500.384.100.422', 'E01.370.225.998.054.422', 'E04.074.422', 'E05.200.500.384.100.422', 'E05.200.998.054.... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Determination of trace elements in different parts of grapefruit by ICP-AES]. | In the present paper, a method of simultaneous determination of trace elements in grapefruit was developed by using inductively coupled plasma-atomic emission spectrometry together with HNO3-HClO4 digestion. The contents of fifteen elements, including B, Ba, Ca, Cu, Zn, Mg, Sr, Mn, Fe, Na, Be, Pb, Bi, Cd and As, were d... | ['Calcium', 'China', 'Citrus paradisi', 'Magnesium', 'Plant Epidermis', 'Seeds', 'Spectrophotometry, Atomic', 'Trace Elements'] | 19,093,588 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['Z01.252.474.164'], ['B01.650.940.800.575.912.250.875.177.538'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['A18.024.750'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['E05.196.712.726.551', 'E05.196.867.826.551'], ['D01.268.811', 'D2... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Rab9 GTPase regulates late endosome size and requires effector interaction for its stability. | Rab9 GTPase resides in a late endosome microdomain together with mannose 6-phosphate receptors (MPRs) and the tail-interacting protein of 47 kDa (TIP47). To explore the importance of Rab9 for microdomain establishment, we depleted the protein from cultured cells. Rab9 depletion decreased late endosome size and reduced ... | ['Cell Membrane', 'DNA-Binding Proteins', 'Endosomes', 'Enzyme Stability', 'HeLa Cells', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Lysosomes', 'Microscopy, Electron', 'Perilipin-3', 'Pregnancy Proteins', 'Protein Binding', 'Protein Transport', 'RNA, Small Interfering', 'Vesicular Transport Proteins', ... | 15,456,905 | [['A11.284.149'], ['D12.776.260'], ['A11.284.430.214.190.875.190.880.337'], ['E05.916.360', 'G02.111.700.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['A11.284.430.214.190.875.190.550'], ['E01.370.350.515.402', 'E0... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Importance of endometrial quality in women with tubal infertility during a natural menstrual cycle for the outcome of IVF treatment. | PURPOSE: The importance of endometrial maturation at estimated time of implantation for the outcome of IVF treatment in regularly menstruating women with tubal infertility was evaluated.METHODS: FSH was measured on cycle day 3, on days 10-15 urine and blood were collected to estimate the day of the LH peak, and E2 and ... | ['Adult', 'Biopsy', 'Embryo Implantation', 'Endometrium', 'Estradiol', 'Female', 'Fertilization in Vitro', 'Follicle Stimulating Hormone', 'Follicular Phase', 'Humans', 'Infertility, Female', 'Luteinizing Hormone', 'Male', 'Menstrual Cycle', 'Pregnancy', 'Pregnancy Rate', 'Progesterone', 'Ultrasonography'] | 9,513,841 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['G08.686.784.170.104.500'], ['A05.360.319.679.490'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Active clearance of corticotropin-releasing factor from the cerebrospinal fluid. | Intracerebroventricular injection of corticotropin-releasing factor (CRF) in animals activates behavioral, motor, metabolic and sympathetic responses similar to those seen with stress. To explore the pharmacokinetics of this peptide in the primate ventricular CSF, we determined the clearance of ovine 125I-CRF from the ... | ['Animals', 'Corticotropin-Releasing Hormone', 'Injections, Intraventricular', 'Kinetics', 'Macaca mulatta', 'Pentetic Acid'] | 3,871,512 | [['B01.050'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['E02.319.267.530.550'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['D02.092.782.590', 'D02.241.081.018.639']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of sleep loss on sleep architecture in Wistar rats: gender-specific rebound sleep. | This study was designed to examine the influence of gender on sleep rebound architecture after a 4-day paradoxical sleep deprivation period. After a 5-day baseline sleep recording, both male and female rats in different phases of the estrus cycle were submitted to paradoxical sleep deprivation for 96 h. After this peri... | ['Animals', 'Darkness', 'Electrocardiography', 'Electromyography', 'Estrous Cycle', 'Female', 'Lighting', 'Male', 'Periodicity', 'Rats', 'Rats, Wistar', 'Sex Characteristics', 'Sleep', 'Sleep Deprivation', 'Sleep Stages', 'Sleep, REM', 'Vagina'] | 18,276,051 | [['B01.050'], ['G01.590.540.233'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.405.255', 'E01.370.530.255'], ['G08.686.195'], ['N06.230.150.410'], ['G01.910.645', 'G07.180.562'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G08.686.815'], ['F02.830.855', 'G11... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
RNase L inhibitor is induced during human immunodeficiency virus type 1 infection and down regulates the 2-5A/RNase L pathway in human T cells. | The interferon-regulated 2-5A/RNase L pathway plays a major role in the antiviral and antiproliferative activities of these cytokines. Several viruses, however, have evolved strategies to escape the antiviral activity of the 2-5A/RNase L pathway. In this context, we have cloned a cDNA coding for the RNase L inhibitor (... | ['Acquired Immunodeficiency Syndrome', 'Adenine Nucleotides', 'Cell Line', 'Down-Regulation', 'Endoribonucleases', 'Enzyme Inhibitors', 'HIV-1', 'Humans', 'Oligoribonucleotides', 'Transfection', 'Virus Replication'] | 9,847,332 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['A11.251.210'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D08.811.277.352... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Causes for the declining proportion of ventricular fibrillation in out-of-hospital cardiac arrest. | AIMS: The reported proportion of ventricular fibrillation (VF) in out-of-hospital cardiac arrest (OHCA) has declined worldwide. VF decline may be caused by less VF at collapse and/or faster dissolution of VF into asystole. We aimed to determine the causes of VF decline by comparing VF proportions in relation to delay f... | ['Aged', 'Cardiopulmonary Resuscitation', 'Emergency Medical Services', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Netherlands', 'Odds Ratio', 'Out-of-Hospital Cardiac Arrest', 'Registries', 'Retrospective Studies', 'Treatment Outcome', 'Ventricular Fibrillation'] | 26,206,596 | [['M01.060.116.100'], ['E02.365.647.110'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['Z01.542.651'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Feasibility of Mindfulness-based Stress Reduction Intervention for Parents of Children with Developmental Delays. | Mindfulness-based stress reduction (MBSR) interventions are popular as a treatment strategy for myriad diagnoses in various settings, and may be beneficial for parents of children with developmental delays (DD). However, prior research suggests extreme levels of stress and extraordinary demands on time among these pare... | ['Adult', 'Child, Preschool', 'Developmental Disabilities', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mindfulness', 'Parents', 'Stress, Psychological'] | 26,379,133 | [['M01.060.116'], ['M01.060.406.448'], ['F03.625.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.551', 'F04.754.137.350.500'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Ferritin based bionanocages as novel biomemory device concept. | Ferritin is an iron cage having protein, capable of extracting metal ions in their cages and a consequence of the electron transfer of metal ions in their cage by reduction and oxidation processes, electrochemical information storage devices can be designed. In this work, ferritin based protein biomemory substrate has ... | ['Amino Acids', 'Biosensing Techniques', 'Copper', 'Electrodes', 'Ferritins', 'Graphite', 'Iron', 'Metals', 'Oxidation-Reduction', 'Signal Processing, Computer-Assisted', 'Silver'] | 29,277,010 | [['D12.125'], ['E05.601.043'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E07.305.250'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D01.268.150.300', 'D01.578.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.552'], ['G02.700', 'G03.295.531'], ['L01.224.800'], ['D01.268.55... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Non-invasive measurement of intraocular pressure by near-infrared spectroscopy. | PURPOSE: To assess a new non-contact method for non-invasive measurement of intraocular pressure (IOP) using near-infrared spectroscopy.DESIGN: Experimental study.METHODS: Eleven porcine eyes were cannulated into the anterior chamber by a needle connected with a water column. Measuring the near-infrared spectrum in dif... | ['Animals', 'Intraocular Pressure', 'Spectroscopy, Near-Infrared', 'Swine', 'Tonometry, Ocular'] | 16,086,952 | [['B01.050'], ['G14.440'], ['E01.370.350.750', 'E05.196.867.851'], ['B01.050.150.900.649.313.500.880'], ['E01.370.380.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning and expression of Methylovorus mays No. 9 gene encoding gamma-glutamylmethylamide synthetase: an enzyme usable in theanine formation by coupling with the alcoholic fermentation system of baker's yeast. | Gamma-glutamylmethylamide synthetase (GMAS), found in an obligate methylotroph, Methylovorus mays No. 9, can form theanine from glutamic acid and ethylamine in a mixture in which yeast sugar fermentation is coupled for ATP regeneration. The internal and N-terminal amino acid sequences of GMAS had certain similarities t... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Betaproteobacteria', 'Carbon-Nitrogen Ligases', 'Cloning, Molecular', 'Escherichia coli', 'Ethanol', 'Fermentation', 'Gene Expression Regulation, Bacterial', 'Gene Expression Regulation, Enzymologic', 'Glutamates', 'Molecular Sequence Data', 'Open Reading Frames', 'Peptide... | 18,175,924 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['B03.660.075'], ['D08.811.464.259'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.033.375'], ['G02.111.158.249', 'G03.191.249'], ['G05.308.300'], ['G05.308.320'], ['D12.125.067.625', 'D12.125.119.409'], ['L01.453.245.667'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
c-met tyrosine kinase receptor expression is associated with abnormal beta-catenin expression and favourable prognostic factors in invasive breast carcinoma. | AIMS: Receptor-type tyrosine kinases are important in cell signal transduction and proliferation. Abnormal expression of tyrosine kinases often leads to malignant transformation. c-met is a tyrosine kinase receptor and its ligand is hepatocyte growth factor (HGF). In this study, we have evaluated c-met expression in 69... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Cadherins', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'Cytoskeletal Proteins', 'Female', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Neoplasm Invasiveness', 'Prognosis', 'Proto-Oncogene Proteins c-met', 'Trans-Activators', 'beta Catenin'] | 10,759,945 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.47... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Elevated levels of perfluoroalkyl acids in family members of occupationally exposed workers: the importance of dust transfer. | The exposure pathways of perfluoroalkyl acids (PFAAs) to humans are still not clear because of the complex living environment, and few studies have simultaneously investigated the bioaccumulative behaviour of different PFAAs in humans. In this study, serum, dust, duplicate diet, and other matrices were collected around... | ['Dust', 'Environmental Exposure', 'Family', 'Fluorocarbons', 'Humans', 'Limit of Detection', 'Occupational Exposure'] | 25,791,573 | [['D20.633.222'], ['N06.850.460.350'], ['F01.829.263', 'I01.880.853.150'], ['D02.455.526.510.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['N06.850.460.350.600']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Isolated Neurogenic Bladder Associated With Human T-Lymphotropic Virus Type 1 Infection in a Renal Transplant Patient From Central Australia: A Case Report. | BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1) is endemic amongst the Aborigines of the Northern Territory of Australia. HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) has been associated with this infection. In general population, isolated neurogenic bladder dysfunction in HTLV-1-infected ... | ['Australia', 'Female', 'HTLV-I Infections', 'Human T-lymphotropic virus 1', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Magnetic Resonance Imaging', 'Middle Aged', 'Oceanic Ancestry Group', 'Pyelonephritis', 'Transplantation, Homologous', 'Urinary Bladder, Neurogenic', 'Viral Load'] | 30,577,291 | [['Z01.639.100', 'Z01.678.100.373'], ['C01.925.782.815.200.470', 'C20.673.483.470'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E01.370.350.8... | ['Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Role of the clock gene Period3 in the human cell-autonomous circadian clock. | Previous studies have shown that mouse Period3 (mPer3) is dispensable for the generation of autonomous oscillations in the circadian clock. However, human studies have suggested that human Period3 (hPer3) may have more important roles in the core clock machinery than mPer3. To investigate the role of hPer3 protein in t... | ['Base Sequence', 'Bone Neoplasms', 'CRISPR-Cas Systems', 'Circadian Clocks', 'Circadian Rhythm', 'Humans', 'Osteosarcoma', 'Period Circadian Proteins', 'Sequence Homology', 'Tumor Cells, Cultured'] | 30,575,220 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.149', 'C05.116.231'], ['G05.308.203.374.394'], ['G07.180.562.094.500'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ['D12.644.360.138.575', 'D12.776.157.530.750.687', 'D12.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transitory effect on endolymphatic hydrops of the intratympanic steroids for M?ni?re's disease. | OBJECTIVES/HYPOTHESIS: This study aimed to evaluate the changes in electrocochleography (EcohG) measurements after intratympanic (IT) dexamethasone therapy and to correlate them with the long-term effects on the control of vertigo.STUDY DESIGN: Prospective outcomes research.METHODS: This study included 62 patients with... | ['Audiometry, Evoked Response', 'Dexamethasone', 'Ear, Middle', 'Endolymphatic Hydrops', 'Female', 'Follow-Up Studies', 'Glucocorticoids', 'Humans', 'Male', 'Meniere Disease', 'Middle Aged', 'Prospective Studies', 'Time Factors', 'Treatment Outcome'] | 25,429,741 | [['E01.370.382.375.060.050'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['A09.246.397'], ['C09.218.568.217'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.21... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
One of the two genomic copies of the glycine decarboxylase cDNA has been deleted at a 5' region in a patient with nonketotic hyperglycinemia. | One of eight patients with nonketotic hyperglycinemia resulted by the lesion in glycine decarboxylase showed the deletion of 0.6-kb SacI and 1.5-kb PstI fragments identified by the cDNA for this protein. A genomic clone, lambda HGDG10, encodes a 5' region of this cDNA in an organized structure and can produce these two... | ['Amino Acid Oxidoreductases', 'Base Sequence', 'Blotting, Southern', 'Chromosome Deletion', 'Cloning, Molecular', 'DNA', 'Deoxyribonucleases, Type II Site-Specific', 'Exons', 'Genomic Library', 'Glycine Dehydrogenase (Decarboxylating)', 'Humans', 'Hyperglycemic Hyperosmolar Nonketotic Coma', 'Molecular Sequence Data',... | 2,268,343 | [['D08.811.682.664.500'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['E05.393.220'], ['D13.444.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A model of practice for the management of velopharyngeal dysfunction. | This paper reviews normal speech production, the speech characteristics associated with velopharyngeal dysfunction, the investigations required and treatment options. A model of service delivery is proposed which has been in place over the past 4 years. This model highlights multidisciplinary management by a specialist... | ['Articulation Disorders', 'Clinical Protocols', 'Endoscopy', 'Humans', 'Medical Audit', 'Palatal Obturators', 'Patient Care Team', 'Pharynx', 'Speech Therapy', 'Velopharyngeal Insufficiency'] | 8,909,722 | [['C10.597.606.150.500.800.150', 'C23.888.592.604.150.500.800.150'], ['E02.183', 'N05.715.360.330.125'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.700.175.500'], ['E06.780.346.850', 'E07.695.190.600'], ['N04.590.715'], ['A03.556.750', 'A04.623', 'A... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Impact of pretreatment body mass index on patients with head-and-neck cancer treated with radiation. | PURPOSE: To investigate the association of pretreatment body mass index (preT BMI) with outcomes of head-and-neck cancer in patients treated with radiotherapy (RT).METHODS AND MATERIALS: All 1,562 patients diagnosed with head-and-neck cancer and treated with curative-intent RT to a dose of 60 Gy or higher were retrospe... | ['Adult', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Educational Status', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Hypopharyngeal Neoplasms', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Nutritional Status', 'Obesity', 'Oropharyngeal Neoplasms', 'Prognosis', 'Radiotherapy Dosage', 'Ret... | 22,342,298 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['N01.824.196'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Selective inhibition of monocyte chemoattractant protein-1 gene expression in human embryonal kidney cells by specific triple helix-forming oligonucleotides. | Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that is expressed by a variety of tissue cells in response to inflammatory stimuli, such as IL-1beta, TNF-alpha, and IFN-gamma. A major function of MCP-1 is the recruitment and activation of monocytes and T lymphocytes. Overexpression of MCP-1 has been implicate... | ['Binding, Competitive', 'Cell Line', 'Chemokine CCL2', 'Gene Expression Regulation', 'Gene Targeting', 'Genetic Vectors', 'Humans', 'Kidney', 'Nucleic Acid Conformation', 'Oligonucleotides', 'Promoter Regions, Genetic', 'Sp1 Transcription Factor'] | 10,657,660 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.251.210'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['G05.308'], ['E05.393.335'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adolescent non-suicidal self-injury (NSSI) in German-speaking countries: comparing prevalence rates from three community samples. | PURPOSE: Non-suicidal self-injury (NSSI) has been recognized as a significant mental health problem in adolescence with high prevalence rates. To date, there are few studies that compare rates of adolescent NSSI between different countries. Thus far no prevalence rates of adolescent NSSI have been reported for Austrian... | ['Adolescent', 'Adolescent Behavior', 'Austria', 'Female', 'Germany', 'Humans', 'Male', 'Prevalence', 'Self-Injurious Behavior', 'Sex Distribution', 'Students', 'Surveys and Questionnaires', 'Switzerland'] | 23,292,435 | [['M01.060.057'], ['F01.145.022'], ['Z01.542.088'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['F01.145.126.980'], ['I01.240.800', 'N01.224.803', 'N06.850.505.400.850'], ['M01.848'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Hilotherm efficacy in controlling postoperative facial edema in patients treated for maxillomandibular malformations. | BACKGROUND: A cooling system based on polyurethane preshaped masks for postoperative cryotherapy, named Hilotherm, has been recently introduced. The purpose of this study was to evaluate the effectiveness of this equipment in controlling postoperative edema and compare the results with those obtained with a group treat... | ['Adult', 'Cryotherapy', 'Edema', 'Facial Asymmetry', 'Female', 'Humans', 'Male', 'Masks', 'Orthognathic Surgery', 'Osteotomy, Le Fort', 'Postoperative Complications', 'Prognathism', 'Statistics, Nonparametric', 'Treatment Outcome'] | 22,067,848 | [['M01.060.116'], ['E02.258'], ['C23.888.277'], ['C23.300.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.325.877.500', 'E07.700.500', 'E07.858.594.750', 'J01.637.708.560.782'], ['E06.892.500', 'H02.163.876.886.500', 'H02.403.810.481'], ['E04.545.575', 'E04.555.580.580', 'E06.645.575'], ['C23.550.767'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Induced dual-nanospray: a novel internal calibration method for convenient and accurate mass measurement. | Accurate mass information is of great importance in the determination of unknown compounds. An effective and easy-to-control internal mass calibration method will dramatically benefit accurate mass measurement. Here we reported a simple induced dual-nanospray internal calibration device which has the following three ad... | ['Calibration', 'Creatine', 'Equipment Design', 'Humans', 'Mass Spectrometry'] | 23,797,862 | [['E05.978.155'], ['D02.078.370.280', 'D12.125.373'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different impacts of manure and chemical fertilizers on bacterial community structure and antibiotic resistance genes in arable soils. | Both manure and chemical fertilizers are widely used in modern agriculture. However, the impacts of different fertilizers on bacterial community structure and antibiotic resistance genes (ARGs) in arable soils still remain unclear. In this study, high-throughput sequencing and quantitative PCR were employed to investig... | ['Agriculture', 'China', 'Drug Resistance, Microbial', 'Fertilizers', 'Genes, Bacterial', 'High-Throughput Screening Assays', 'Manure', 'Metagenomics', 'Microbiota', 'Soil', 'Soil Microbiology'] | 28,898,777 | [['J01.040'], ['Z01.252.474.164'], ['G06.225', 'G07.690.773.984.269'], ['D27.720.031.400'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['E05.916.680'], ['D20.601'], ['H01.158.273.343.350.261'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['D20.721',... | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
[Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia]. | We reported the results of 6 allogenic bone marrow transplantation (BMT) and 3 autologous BMT for patients with Philadelphia chromosome (Ph1)-positive acute lymphoblastic leukemia (ALL) by Nagoya BMT group. Two of six patients who received allogenic BMT have continued complete remission (CR) on +639 days and +1,597 day... | ['Adolescent', 'Adult', 'Bone Marrow Transplantation', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Philadelphia Chromosome', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma'] | 1,942,524 | [['M01.060.057'], ['M01.060.116'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.187.520.300.325.345.500', 'A11.284.187.520.300.505.515.500', 'C23.550.210.870.680', 'G05.360.162.520.300.325.345.700', 'G05.360.162.520.300.505.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nosocomial outbreak of systemic candidosis associated with parenteral nutrition. | Eight patients in two surgical units developed systemic candidosis during a 40-day period from June 5 to July 13, 1987 (in five cases Candida albicans was identified). Three of them died. All cases belonged to a group of 27 patients receiving parenteral nutrition (PN), while among the 108 patients who did not receive P... | ['Aged', 'Candidiasis', 'Case-Control Studies', 'Cross Infection', 'Disease Outbreaks', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Parenteral Nutrition, Total', 'Retrospective Studies', 'Serotyping'] | 2,105,353 | [['M01.060.116.100'], ['C01.150.703.160'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.248', 'C23.550.291.875.500'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['E02.421.505.575', 'E02.642.500.505.750'], ['E05.318.372.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Treatment of pancreonecrosis with lesion of retroperitoneal adipose tissue]. | The results of treatment of 122 patients with pancreonecrosis (PN) with lesion of retroperitoneal fat tissue (RFT) were analyzed. Twenty-four patients underwent emergency and urgent surgery, drainage of RFT through lumbotomy was performed. Nine (37,5%) patients died. Sixty-six patients with aseptic PN were treated cons... | ['Adipose Tissue', 'Drainage', 'Humans', 'Pancreatitis, Acute Necrotizing', 'Retroperitoneal Space', 'Treatment Outcome'] | 14,983,147 | [['A10.165.114'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.689.750.650'], ['A01.923.047.025.750'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Foveal versus eccentric retinal critical flicker frequency in mild traumatic brain injury. | BACKGROUND: The purpose of this study was to assess the critical flicker fusion frequency (CFF) at the fovea and at 10 degrees of horizontal retinal eccentricity and to determine if there was a correlation between CFF and the degree of light and motion sensitivity in individuals with mild traumatic brain injury (TBI).M... | ['Adolescent', 'Adult', 'Aged', 'Brain Injuries', 'Female', 'Flicker Fusion', 'Fovea Centralis', 'Humans', 'Male', 'Middle Aged', 'Retina', 'Severity of Illness Index', 'Young Adult'] | 19,861,221 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E01.370.380.245', 'F02.463.593.932.458', 'G14.370'], ['A09.371.729.522.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A09.371.729'], ['E05.318.308.980.438.475.456.500', 'N... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of left ventricular pressure unloading during LVAD support on right ventricular contractility. | The effects of left ventricular pressure (LVP) unloading with a left ventricular assist device (LVAD) on right ventricular (RV) end-systolic pressure volume relationships were studied. A Thoratec (Berkeley, CA) LVAD was implanted in open chest anesthetized pigs via apical cannulation, and an electromagnetic flow probe ... | ['Animals', 'Blood Pressure', 'Evaluation Studies as Topic', 'Heart-Assist Devices', 'Hemodynamics', 'Myocardial Contraction', 'Swine', 'Ventricular Function, Left', 'Ventricular Function, Right'] | 1,457,905 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.337', 'N05.715.360.335'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['G09.330.380'], ['G09.330.580', 'G11.427.494.570'], ['B01.050.150.900.649.313.500.880'], ['G09.330.955.800'], ['G09.330.955.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Eighteen-point abobotulinum toxin a upper face rejuvenation: an eye plastic perspective on 845 subjects. | PURPOSE: To report the method and results of 18-point Abobotulinum toxin A (ABO-BTA, Dysport) upper face rejuvenation on 845 subjects.METHODS: In a retrospective chart review, all subjects (the first cycle of injection) with ABO-BTA upper face rejuvenation from 2003 to 2009 were included. Excluded were subjects with fa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Botulinum Toxins, Type A', 'Eyebrows', 'Eyelids', 'Facial Muscles', 'Female', 'Forehead', 'Humans', 'Injections, Intradermal', 'Male', 'Middle Aged', 'Neuromuscular Agents', 'Orbit', 'Rejuvenation', 'Rhytidoplasty', 'Skin', 'Skin Aging', 'Young Adult'] | 24,481,513 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['A01.456.505.420.338', 'A17.360.296'], ['A01.456.505.420.504', 'A09.371.337'], ['A02.633.567.400', 'A14.363'], ['A01.456.505.580'], ['B01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An alternative treatment for iatrogenic right ventricular puncture in primary percutaneous intervention. | Right ventricle perforation is an uncommon, but potentially fatal, possible complication of pericardiocentesis. We presented a case of right ventricular perforation that developed during urgent pericardiocentesis due to tamponade. This case was successfully treated with the incremental removal of the drainage catheter,... | ['Cardiac Tamponade', 'Heart Injuries', 'Heart Ventricles', 'Humans', 'Iatrogenic Disease', 'Paracentesis', 'Percutaneous Coronary Intervention'] | 28,990,945 | [['C14.280.155'], ['C26.891.375'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ['E01.370.225.998.329', 'E02.309.805', 'E02.800.550', 'E04.237.667', 'E04.665.600', 'E05.200.998.329'], ['E04.100.814.529.968', 'E04.502.382.968']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New green synthesis and formulations of acyclovir prodrugs. | Different green synthesis of alkyl esters of acyclovir (acyclovir prodrugs) is described. Hexanoic, decanoic, dodecanoic and tetradecanoic acyclovir esters were synthesized reacting acyclovir and the respective acid anhydride in dimethyl sulfoxide (DMSO), in solvents from renewable sources and without solvent (T=30 °C)... | ['Acyclovir', 'Antiviral Agents', 'Chemistry, Pharmaceutical', 'Green Chemistry Technology', 'Hydrogels', 'Prodrugs'] | 21,881,250 | [['D03.633.100.759.758.399.454.250'], ['D27.505.954.122.388'], ['H01.158.703.007', 'H01.181.466'], ['J01.897.360'], ['D20.280.320.375', 'D26.255.165.320.375'], ['D26.675']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of prostaglandins on elicitation of anti-viral-cytolytic activity. | We have studied the modulating effect of prostaglandins (PG) on the elicitation of secondary anti-vesicular stomatitis virus (VSV) cytotoxic T-lymphocytes (CTL) with viral antigens. The results indicate that PGE1 and PGE2 both inhibit the induction of anti-VSV CTLs by ultraviolet-inactivated VSV. Consistent with the re... | ['Alprostadil', 'Animals', 'Cells, Cultured', 'Cytotoxicity, Immunologic', 'Dinoprostone', 'Female', 'Indomethacin', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Prostaglandins', 'Prostaglandins E', 'Spleen', 'T-Lymphocytes', 'Vesicular stomatitis Indiana virus'] | 6,281,179 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['A11.251'], ['G12.287'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D03.633.100.473.420'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.99... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The distribution of ovulations from the ovaries of merino and Border Leicester x merino ewes and its effect on the survival of their embryos. | The distribution of ovulation between the right and the left ovary was recorded using endoscopy, in 2806 ewes over a 5-year period. Fifteen separate tests were conducted as part of the development programme for a commercial twinning vaccine. There were significantly more ovulations on the right ovary (53.4%) compared t... | ['Animals', 'Embryo, Mammalian', 'Female', 'Litter Size', 'Ovary', 'Ovulation', 'Sheep'] | 9,360,771 | [['B01.050'], ['A16.254'], ['G08.686.530', 'G08.686.784.769.498.300'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['G08.686.784.690'], ['B01.050.150.900.649.313.500.380.791']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early Cranioplasty is Associated with Greater Neurological Improvement: A Systematic Review and Meta-Analysis. | BACKGROUND: Cranioplasty after decompressive craniectomy is a common neurosurgical procedure, yet the optimal timing of cranioplasty has not been well established.OBJECTIVE: To investigate whether the timing of cranioplasty is associated with differences in neurological outcome.METHODS: A systematic literature review a... | ['Adult', 'Decompressive Craniectomy', 'Female', 'Glasgow Coma Scale', 'Humans', 'Karnofsky Performance Status', 'Male', 'Nervous System Diseases', 'Neurologic Examination', 'Neurosurgical Procedures', 'Prospective Studies', 'Retrospective Studies', 'Skull', 'Treatment Outcome'] | 28,419,358 | [['M01.060.116'], ['E04.188.200', 'E04.525.190.200'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.475.456.500.500', 'N05.715.360.300.800.438.375.364.500.500', 'N06.850.520.308.980.438... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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