Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients. | BACKGROUND: Asthenozoospermia is one of the most common findings present in infertile males characterized by reduced or absent sperm motility, but its aetiology remains unknown in most cases. In addition, calcium is one of the most important ions regulating sperm motility. In this study we have investigated the progest... | ['Actin Cytoskeleton', 'Asthenozoospermia', 'Biological Transport', 'Calcium', 'Calcium Signaling', 'Cytochalasin D', 'Cytosol', 'Depsipeptides', 'Enzyme Inhibitors', 'Humans', 'Male', 'Progesterone', 'Progestins', 'Spermatozoa', 'Thapsigargin'] | 19,200,382 | [['A11.284.430.214.190.750.050'], ['C12.294.365.700.253'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D03.633.100.473.231.450', 'D23.946.587.370.450'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D04.3... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of Lymphocyte Subsets in the Immune Response to Primary B Cell-Derived Exosomes. | Exosomes are lipid nanovesicles released after fusion of the endosomal limiting membrane with the plasma membrane. In this study, we investigated the requirement for CD4 T cells, B cells, and NK cells to provide help for CD8 T cell-mediated response to B cell-derived exosomes. CTL responses to Ag-loaded exosomes were d... | ['Animals', 'B-Lymphocytes', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cross-Priming', 'Cytotoxicity, Immunologic', 'Dendritic Cells', 'Exosomes', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Lymphocyte Subsets', 'Mice, Inbred C57BL', 'Microscopy, Electron', 'Receptors, Antigen, B-Cell', 'T-Lym... | 28,842,467 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.56... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of maternal lineage structure of individuals from chamber graves placed in medieval cemetery in Ka?dus, Central Poland. | The beginning of the early Middle Ages period in Poland (10th-14th century) has been widely debated in the context of an active demographic inflow from other countries and its contribution to the creation of the new country. Finding chamber graves which are considered typical for the Scandinavian ethnic group in a few ... | ['Adult', 'Anthropology, Physical', 'Cemeteries', 'Child', 'DNA, Mitochondrial', 'European Continental Ancestry Group', 'Female', 'Haplotypes', 'History, Medieval', 'Humans', 'Male', 'Poland'] | 31,939,994 | [['M01.060.116'], ['I01.076.368'], ['I01.076.201.450.550.150.500', 'J03.150'], ['M01.060.406'], ['D13.444.308.283.225'], ['M01.686.508.400'], ['G05.380.360'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.679']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 |
Differentiation of CO isotopic variants by frequency tuning a terahertz source. | The transmission spectra of two CO isotopic variants, i.e., (12)CO and (13)CO, are measured with a recently developed widely tunable THz source. The pure rotational transition lines of J=6 --> 7, 10 --> 11, 11 --> 12, 12 --> 13, and 13 --> 14 have been identified in the spectra. The transition frequencies and the rotat... | ['Carbon Monoxide', 'Equipment Design', 'Fourier Analysis', 'Isotopes', 'Models, Chemical', 'Quantum Theory', 'Spectrophotometry', 'Spectroscopy, Fourier Transform Infrared'] | 17,571,134 | [['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['E05.320'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['D01.496'], ['E05.599.495'], ['H01.671.579.800'], ['E05.196.712.726', 'E05.196.867.826'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. | Interleukin 1 beta (IL-1beta) is a proinflammatory cytokine that is considered to play an important role in the progression of rheumatoid arthritis (RA). A stimulus such as ATP is necessary to cause the release of mature IL-1beta, via activation of the P2X(7) receptor on monocytes. In this study, the production of IL-1... | ['Adenosine Triphosphate', 'Adult', 'Arthritis, Rheumatoid', 'Case-Control Studies', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Flow Cytometry', 'Humans', 'Interleukin-1beta', 'Leukocytes, Mononuclear', 'Lipopolysaccharide Receptors', 'Lipopolysaccharides', 'Male', 'Middle Aged', 'Receptors, Pur... | 18,040,764 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.4... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of segment polarity genes in brachiopods supports a non-segmental ancestral role of engrailed for bilaterians. | The diverse and complex developmental mechanisms of segmentation have been more thoroughly studied in arthropods, vertebrates and annelids-distantly related animals considered to be segmented. Far less is known about the role of "segmentation genes" in organisms that lack a segmented body. Here we investigate the expre... | ['Animals', 'Arthropod Proteins', 'Arthropods', 'Body Patterning', 'Embryo, Nonmammalian', 'Evolution, Molecular', 'Gene Expression Regulation, Developmental', 'Homeodomain Proteins', 'Larva', 'Phylogeny', 'Transcription Factors', 'Wnt1 Protein'] | 27,561,213 | [['B01.050'], ['D12.776.093'], ['B01.050.500.131'], ['G07.345.500.100'], ['A13.350', 'A16.331'], ['G05.045.250', 'G16.075.250'], ['G05.308.310'], ['D12.776.260.400'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D12.776.930'], ['D12.776.467.984.100', 'D12.776.624.664.700.967'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Isolated oculomotor nerve palsy in a child caused by an internal carotid aneurysm. | Common causes for acquired isolated oculomotor nerve palsy in children are trauma, inflammation, and neoplasia. We report a case of isolated oculomotor nerve palsy in a 13-year-old boy secondary to intracranial carotid aneurysm. | ['Adolescent', 'Aneurysm', 'Carotid Artery Diseases', 'Carotid Artery, Internal', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Oculomotor Nerve Diseases'] | 24,210,342 | [['M01.060.057'], ['C14.907.055'], ['C10.228.140.300.200', 'C14.907.253.123'], ['A07.015.114.186.200.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.292.562.700', 'C11.590.436']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Altered lymphocyte antigen expressions in HIV infection: a study by quantitative flow cytometry. | To identify surface antigen changes that may contribute to the immune deficiency in infection with the human immunodeficiency virus (HIV), we quantified, by double-staining flow cytometry, the number of antigens of the main peripheral blood lymphocyte subsets from 30 HIV-positive persons and compared them with those of... | ['Adult', 'Animals', 'Antigens, CD7', 'Antigens, Surface', 'CD2 Antigens', 'CD3 Complex', 'CD4 Antigens', 'CD56 Antigen', 'CD8 Antigens', 'Disease Progression', 'Female', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'HIV Infections', 'Humans', 'Killer Cells, Natural', 'Lymphocytes', 'Male', 'Mice', 'Phenotype'] | 9,353,099 | [['M01.060.116'], ['B01.050'], ['D23.050.301.264.035.107', 'D23.050.301.264.894.107', 'D23.101.100.894.107'], ['D23.050.301'], ['D23.050.301.264.894.090', 'D23.101.100.894.090'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.8... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. | Terminal erythroid differentiation in vertebrates is characterized by progressive heterochromatin formation and chromatin condensation and, in mammals, culminates in nuclear extrusion. To date, although mechanisms regulating avian erythroid chromatin condensation have been identified, little is known regarding this pro... | ['Animals', 'Cell Differentiation', 'Chickens', 'Chromatin', 'Erythroblasts', 'Friend murine leukemia virus', 'Histone Deacetylase Inhibitors', 'Histone Deacetylases', 'Histones', 'Hydroxamic Acids', 'Mice', 'Nucleosomes'] | 19,172,406 | [['B01.050'], ['G04.152'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['A11.148.378.590.837.250.200', 'A11.443.240.497.200', 'A15.378.316.378.590.837.250.200'], ['B04.613.807.375.525.225', 'B04.820.650.375.525.225'], ['D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA bending is an important component of site-specific recognition by the TATA binding protein. | We have used gel electrophoretic methods to analyze the extent, location and direction of the DNA bend induced by the TATA binding protein (TBP) upon binding to a consensus TATA box sequence. Our observations were consistent with the proposed models for the X-ray crystal structure of the TBP-TATA box complex. We have a... | ['Base Composition', 'Base Sequence', 'Binding Sites', 'DNA', 'DNA-Binding Proteins', 'Deoxyribonuclease I', 'Electrophoresis, Polyacrylamide Gel', 'Molecular Sequence Data', 'Mutation', 'Nucleic Acid Conformation', 'TATA Box', 'TATA-Box Binding Protein', 'Transcription Factors', 'Transcription, Genetic'] | 7,616,566 | [['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D13.444.308'], ['D12.776.260'], ['D08.811.277.352.335.350.250'], ['E05.196.401.402', 'E05.301.300.319'], ['L01.453.245.667'], ['G05.365.590'], ['G02.111.570.820.486', 'G05.360.580'], ['G02.111.570.080.689.675.850', 'G05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effects of plane rotation on the recognition of brief masked pictures of familiar objects. | Two experiments examined the effects of plane rotation on the recognition of briefly displayed pictures of familiar objects, using a picture-word verification task. Mirroring the results of earlier picture naming studies (Jolicoeur, 1985; Jolicoeur & Milliken, 1989), plane rotation away from a canonical upright orienta... | ['Adult', 'Analysis of Variance', 'Attention', 'Confidence Intervals', 'Humans', 'Orientation', 'Pattern Recognition, Visual', 'Perceptual Masking', 'Semantics', 'Time Factors'] | 9,701,970 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.071.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Retroperitoneal schwannoma extending into the intravertebral foramen. | A 35-year-old Japanese man first visited the hospital for episodes of numbness in the right medial femoral region and loss of muscular strength in the right thigh. A CT scan of the abdomen showed a 10 x 9-cm well-circumscribed in homogeneous multilayered mass, in contact with the lumbar vertebrae. MRI demonstrated a hy... | ['Adult', 'Humans', 'Lumbar Vertebrae', 'Male', 'Neoplasm Invasiveness', 'Neurilemmoma', 'Retroperitoneal Neoplasms', 'Spinal Cord Neoplasms'] | 12,119,445 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['C04.697.645', 'C23.550.727.645'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', 'C04.557.580.625.650.595'], ['C04.588.033.731'], ['C04.588.614.250.803', 'C10.228.854.765', 'C10.551.240.750']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Role of MDR-Acinetobacter baumannii in Orthopedic Surgical Site Infections. | BACKGROUND: Gram-positive microorganisms were the main causative organisms of orthopedic surgical site infections (SSI); however the rising incidence of multiple drug resistant Acinetobacter baumannii (MDR-AB) infections in orthopedic operations causes a great concern because of their limited array of therapeutic optio... | ['Acinetobacter Infections', 'Acinetobacter baumannii', 'Bacteriological Techniques', 'Culture Media', 'DNA, Bacterial', 'Drug Resistance, Multiple, Bacterial', 'Humans', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Mass Screening', 'Methicillin-Resistant Staphylococcus aureus', 'Orthopedic Procedures', 'Polymera... | 26,114,551 | [['C01.150.252.400.560.022'], ['B03.440.400.425.537.050.099', 'B03.660.250.530.050.099'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B01.050.150.900.649.313.988.400.1... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Breast fibroadenoma with pseudoangiomatous (PASH-like) stroma. | Pseudoangiomatous stromal hyperplasia (PASH) is a breast stromal change, histologically characterized by anastomosing, slit-like spaces lined by slender myofibroblasts and surrounded by dense collagenous stroma. Mass forming cases clinically and radiologically simulate fibroadenoma. A middle aged women presented with u... | ['Adult', 'Angiomatosis', 'Biopsy, Fine-Needle', 'Breast', 'Breast Diseases', 'Breast Neoplasms', 'Diagnosis, Differential', 'Female', 'Fibroadenoma', 'Humans', 'Hyperplasia', 'Mastectomy, Segmental', 'Ultrasonography, Mammary'] | 28,777,747 | [['M01.060.116'], ['C14.907.077'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['A01.236'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo. | Pre-implantation development requires the specification and organization of embryonic and extra-embryonic lineages. The separation of these lineages takes place when asymmetric divisions generate inside and outside cells that differ in polarity, position and fate. Here we assess the global transcriptional identities of... | ['Animals', 'Bone Morphogenetic Protein 4', 'Bone Morphogenetic Protein 7', 'Bone Morphogenetic Protein Receptors, Type II', 'Cell Lineage', 'Embryo Implantation', 'Endoderm', 'Female', 'Gene Expression Regulation, Developmental', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Signal Transduction', 'Smad4 P... | 25,514,175 | [['B01.050'], ['D12.644.276.954.200.400', 'D12.776.467.942.200.400', 'D23.529.942.200.400'], ['D12.644.276.954.200.700', 'D12.776.467.942.200.700', 'D23.529.942.200.700'], ['D08.811.913.696.620.682.700.109.750', 'D12.776.543.750.750.400.049.750'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of TGF?1 and its receptors is associated with biological features of ovarian cancer and sensitivity to paclitaxel/carboplatin. | It has been suggested that expression of TGF?1 and its receptors [TGF? receptor type I (T?RI) and TGF? receptor type II (T?RII)] may play a key role in the proliferation and progression of epithelial ovarian cancer. We investigated the biological significance of TGF?1 and its receptors, as well as their association wit... | ['Adenocarcinoma, Clear Cell', 'Adenocarcinoma, Mucinous', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Carboplatin', 'Carcinoma, Endometrioid', 'Cystadenocarcinoma, Serous', 'Drug Resistance, Neoplasm', 'Fallopian Tube Neoplasms', 'Female', 'Humans', 'Immunoenzyme Techniques... | 21,249,319 | [['C04.557.470.200.025.045'], ['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.257.125'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro efficacy of Duddingtonia flagrans against nematodes of sheep based on in vivo calculations. | Duddingtonia flagrans has been tested as an alternative parasite control, but data from in vitro experiments based on in vivo calculations describing nematophagous fungi predation in nematodes are restricted. The objective of this work was to determine the efficacy of D. flagrans against sheep nematode larvae in vitro ... | ['Animals', 'Biological Control Agents', 'Duddingtonia', 'Female', 'Larva', 'Nematoda', 'Parasitology', 'Sheep', 'Sheep Diseases', 'Treatment Outcome'] | 29,069,157 | [['B01.050'], ['D20.215.113'], ['B01.300.381.299'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.500.500.294'], ['H01.158.273.688'], ['B01.050.150.900.649.313.500.380.791'], ['C22.836'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Studies on topical antiinflammatory agents. I. Synthesis and vasoconstrictive activity of corticosteroid 17-succinyl esters. | A series of 17-succinyl derivatives of four corticosteroids was prepared. They were tested for vasoconstrictive activity in humans, using 9 alpha-fluoro-11 beta, 21-dihydroxy-16 beta-methyl-17 alpha-valeryloxy-1,4-pregnadiene-3,20-dione (betamethasone 17-valerate, BV) as a standard. The activities of the 21-chloro 17-m... | ['Administration, Topical', 'Animals', 'Anti-Inflammatory Agents', 'Betamethasone Valerate', 'Chemical Phenomena', 'Chemistry', 'Rabbits', 'Structure-Activity Relationship', 'Vasoconstrictor Agents'] | 2,776,236 | [['E02.319.267.120'], ['B01.050'], ['D27.505.954.158'], ['D04.210.500.745.432.769.199.150', 'D04.210.500.908.093.150'], ['G02'], ['H01.181'], ['B01.050.150.900.649.313.968.700'], ['G02.111.830', 'G07.690.773.997'], ['D27.505.954.411.793']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Emergency department management of occupational exposures to HIV-infected fluids. | The emergency department is where many healthcare workers will seek medical advice and care after a potential exposure to bodily fluids contaminated with the human immunodeficiency virus (HIV). The estimated risk of HIV infection in healthcare workers with percutaneous exposures to HIV-infected blood is estimated at 0.... | ['Anti-HIV Agents', 'Emergency Service, Hospital', 'France', 'HIV Infections', 'Health Personnel', 'Humans', 'Occupational Diseases', 'Occupational Exposure', 'United Kingdom', 'United States', 'Zidovudine'] | 10,195,483 | [['D27.505.954.122.388.077.088'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['Z01.542.286'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of pulsed magnetic fields in the therapy of osteoporosis induced by ovariectomy in the rat. | This paper presents preliminary results on the effects of pulsed electromagnetic fields (EMF) in the therapy of post menopausal osteoporosis induced by ovariectomy in female rats aged ten months. In particular, the effects of the intensity of pulsed EMF applied at constant frequency has been studied. Magnetic fields pu... | ['Animals', 'Bone Density', 'Female', 'Humans', 'Magnetics', 'Osteogenesis', 'Osteoporosis, Postmenopausal', 'Ovariectomy', 'Rats', 'Rats, Sprague-Dawley'] | 8,155,304 | [['B01.050'], ['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.493'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['C05.116.198.579.610', 'C18.452.104.579.610'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Histochemical localization of neuraminidase in the CNS of mice and fish by means of 5-brom-3-indolyl-alpha-ketoside of 5-N-acetyl-D-neuraminic acid (BI-NeuAc). | The applicability of the 5-brom-3-indolyl-alpha-ketoside of N-acetyl-D-neuraminic acid (BI-NeuAc) as substrate for the histochemical indication of neuraminidase (GOSSRAU et al. 1977) was examined in frozen sections of brain, small intestine and kidney from suckling and adult mice and respectively from a cichlid fish (S... | ['Animals', 'Brain', 'Fishes', 'Histocytochemistry', 'Intestine, Small', 'Kidney', 'Male', 'Mice', 'Neuraminidase', 'Sialic Acids', 'Species Specificity', 'Staining and Labeling'] | 6,195,879 | [['B01.050'], ['A08.186.211'], ['B01.050.150.900.493'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A03.556.124.684'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.277.450.692'], ['D02.241... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Splenic Abscess Caused by Salmonella Typhi and Co-Infection with Leptospira. | Splenic abscesses caused by Salmonella typhi are a very rare complication of typhoid fever in this era of use of specific antibiotics. Co-infection with Leptospira in such a patient is even rarer. Clinical diagnosis of splenic abscess caused by Salmonella is difficult owing to its rarity, being insidious in onset and h... | ['Abscess', 'Coinfection', 'Humans', 'Leptospira', 'Male', 'Salmonella typhi', 'Splenic Diseases', 'Typhoid Fever', 'Young Adult'] | 29,327,530 | [['C01.830.025', 'C23.550.470.756.100'], ['C01.218'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.400.425.475.475', 'B03.851.475.475'], ['B03.440.450.425.800.200.800', 'B03.660.250.150.710.160.750'], ['C15.604.744'], ['C01.150.252.400.310.821.873'], ['M01.060.116.815']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Investigation of beta-Lactamases in clinical isolates of Staphylococcus aureus for further explanation of borderline methicillin resistance. | BACKGROUND: Borderline methicillin resistance in Staphylococcus aureus is due to beta-lactamase overproduction and/or specific methicillinases.METHODS: beta-Lactamase activity in culture supernatants and in cytoplasmic membrane fractions was estimated by bioassay and by SDS-PAGE combined with nitrocefin assay.RESULTS: ... | ['Humans', 'Membrane Proteins', 'Methicillin Resistance', 'Microbial Sensitivity Tests', 'Staphylococcus aureus', 'beta-Lactamases'] | 16,224,179 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytogenetic findings in pituitary adenoma: results of a pilot study. | Pituitary adenomas are the most common tumors of the sellar region and are, with rare exception, benign neoplasms. The natural history of these lesions is only poorly understood and, although histologic, immunocytologic, and ultrastructural characteristics have been well established, predicting the natural history of i... | ['Adenoma', 'Adult', 'Aged', 'Female', 'Humans', 'Karyotyping', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Pilot Projects', 'Pituitary Neoplasms', 'Tumor Cells, Cultured'] | 8,346,476 | [['C04.557.470.035'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.727.645'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.8... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Relaxation of functional constraint on light-independent protochlorophyllide oxidoreductase in Thuja. | The light-independent protochlorophyllide oxidoreductase (DPOR) plays a key role in the ability of nonflowering plants and algae to synthesize chlorophyll in darkness. This enzyme consists of three subunits encoded by the chlB, chlL, and chlN genes in the plastid genome. Previously, we found a high nonsynonymous substi... | ['Evolution, Molecular', 'Light', 'Mutation', 'Oxidoreductases Acting on CH-CH Group Donors', 'Phenotype', 'Phylogeny', 'RNA Editing', 'Reverse Transcriptase Polymerase Chain Reaction', 'Seeds', 'Sequence Analysis, DNA', 'Species Specificity', 'Thuja', 'Time Factors'] | 16,428,257 | [['G05.045.250', 'G16.075.250'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G05.365.590'], ['D08.811.682.660'], ['G05.695'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.760.250', 'G03.839.250', 'G05.308.700.250'], ['E05.393.620.500.725'], ['A18.024.500.750', 'G07.203.300.77... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
The ADA in action at health care facilities. | The purpose of the work documented here was to assist defendants in legal actions to comply with settlement agreements, consent decrees, and memoranda of understanding. The work involved surveying medical center facilities and interviewing the staff and, based on the results, developing recommendations for compliance. ... | ['Architectural Accessibility', 'Communication Barriers', 'Disabled Persons', 'Government Regulation', 'Health Care Surveys', 'Health Facilities', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Humans', 'Organizational Policy', 'United States'] | 21,122,793 | [['J01.086.339.070'], ['L01.143.230'], ['M01.150'], ['I01.880.604.394', 'N03.706.358'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N02.278'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.... | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Neuroprotective mechanism of ischemic postconditioning in mice: a possible relationship between protein kinase C and nitric oxide pathways. | BACKGROUND: The present study was conducted to pharmacologically investigate the role of protein kinase C (PKC) pathway in neuroprotective mechanism of ischemic postconditioning (iPoCo) and determine the influence of nitric oxide (NO) signaling in PKC-mediated effects.MATERIALS AND METHODS: Bilateral carotid artery occ... | ['Animals', 'Arginine', 'Benzophenanthridines', 'Brain Infarction', 'Cerebrum', 'Ischemic Preconditioning', 'Male', 'Memory', 'Mice', 'Neural Pathways', 'Nitric Oxide', 'Protein Kinase C', 'Psychomotor Performance', 'Rotarod Performance Test'] | 24,655,662 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D03.132.089', 'D03.633.300.633.207', 'D03.633.400.131'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['A08.186.211.200.885.287'], ['E02.592',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Host defense against oral microbiota by bone-damaging T cells. | The immune system evolved to efficiently eradicate invading bacteria and terminate inflammation through balancing inflammatory and regulatory T-cell responses. In autoimmune arthritis, pathogenic TH17 cells induce bone destruction and autoimmune inflammation. However, whether a beneficial function of T-cell-induced bon... | ['Alveolar Bone Loss', 'Animals', 'Bacteremia', 'Disease Models, Animal', 'Female', 'Interleukin-6', 'Mice, Inbred C57BL', 'Microbiota', 'Mouth', 'Periodontitis', 'RANK Ligand', 'Th17 Cells', 'Tooth Loss'] | 29,453,398 | [['C05.116.264.150', 'C07.465.714.354.500'], ['B01.050'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Scalable gastroscopic video summarization via similar-inhibition dictionary selection. | OBJECTIVE: This paper aims at developing an automated gastroscopic video summarization algorithm to assist clinicians to more effectively go through the abnormal contents of the video.METHODS AND MATERIALS: To select the most representative frames from the original video sequence, we formulate the problem of gastroscop... | ['Algorithms', 'Artificial Intelligence', 'Case-Control Studies', 'Data Compression', 'Gastroscopy', 'Humans', 'Image Interpretation, Computer-Assisted', 'Pattern Recognition, Automated', 'Predictive Value of Tests', 'Reproducibility of Results', 'Stomach Diseases', 'Video Recording'] | 26,363,682 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['L01.224.308.189', 'L01.224.800.500', 'L01.470.500'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['B01.050.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Rinderpest virus H protein: role in determining host range in rabbits. | A major molecular determinant of virus host-range is thought to be the viral protein required for cell attachment. We used a recombinant strain of Rinderpest virus (RPV) to examine the role of this protein in determining the ability of RPV to replicate in rabbits. The recombinant was based on the RBOK vaccine strain, w... | ['Animals', 'Antibodies, Viral', 'Cattle', 'Cell Line', 'Disease Models, Animal', 'Enzyme-Linked Immunosorbent Assay', 'Giant Cells', 'Glycoproteins', 'Hemagglutinins, Viral', 'Lymphoid Tissue', 'Necrosis', 'Rabbits', 'Recombination, Genetic', 'Rinderpest', 'Rinderpest virus', 'Species Specificity', 'Vaccines, Syntheti... | 12,029,161 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Synthesis of 2-substituted derivatives of 5H-1,2,4-thiadiazolo[3,2-a] [1,3,5]triazin-5-one]. | The synthesis of 2-substituted derivatives of 5H-1,3,4-thiadiazolo[3,2-a] [1,3,5]triazin-5-one, obtained from 5-substituted 2-amino-1,3,4-thiadiazoles is described. The structure of the new compounds is confirmed by U.V. and I.R. spectra and partly by mass spectrometry. | ['Chemical Phenomena', 'Chemistry', 'Cyclization', 'Mass Spectrometry', 'Spectrophotometry, Infrared', 'Spectrophotometry, Ultraviolet', 'Thiadiazoles', 'Triazines'] | 620,773 | [['G02'], ['H01.181'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['E05.196.566'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D02.886.675.867', 'D03.383.129.708.867'], ['D03.383.931']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Trifluoroleucine resistance and regulation of alpha-isopropyl malate synthase in Saccharomyces cerevisiae. | Seven spontaneous Saccharomyces cerevisiae mutants that express dominant resistance to 5,5,5-trifluoro-DL-leucine have been characterised at the molecular level. The gene responsible for the resistance was cloned from one of the mutants (FSC2.4). Determination of its nucleotide sequence showed that it was an allele of ... | ['2-Isopropylmalate Synthase', 'Alleles', 'Amino Acid Sequence', 'Blotting, Northern', 'Cloning, Molecular', 'Coenzyme A', 'DNA Mutational Analysis', 'Drug Resistance, Microbial', 'Gene Deletion', 'Genes, Fungal', 'Leucine', 'Molecular Sequence Data', 'Mutation', 'Plasmids', 'RNA, Fungal', 'Recombinant Fusion Proteins'... | 10,071,221 | [['D08.811.913.050.614'], ['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.393.220'], ['D03.633.100.759.646.138.382', 'D08.211.211', 'D13.695.667.138.382', 'D13.695.827.068.382'], ['E05.393.760.700.300'], ['G06.225', 'G07.690.773.984.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Glutathione is the main endogenous inhibitor of protein glycation. | Glycation is the cause of diabetic complications and contributes to the development of other diseases and aging. Numerous exogenous compounds have been tested for their anti-glycating activity. The aim of this study was to answer the question, which endogenous compounds at physiological concentrations can effectively p... | ['Adult', 'Blood Proteins', 'Cells, Cultured', 'Female', 'Glucose', 'Glutathione', 'Glycation End Products, Advanced', 'Hemoglobins', 'Humans', 'Serum Albumin, Bovine'] | 28,218,612 | [['M01.060.116'], ['D12.776.124'], ['A11.251'], ['D09.947.875.359.448'], ['D12.644.456.448'], ['D12.776.643.500'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.034.841.540', 'D12.776.124.727.875']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intraoperative esophageal manometry and early postoperative esophageal pH monitoring in children. | Intraoperative esophageal manometry has not been correlated with early postoperative extended esophageal pH monitoring (EEpHM) in children with gastroesophageal reflux. Twenty-seven children were studied with the following design: (1) abnormal preoperative EEpHM; (2) intraoperative measurement of lower esophageal high ... | ['Child', 'Child, Preschool', 'Esophagus', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Infant', 'Infant, Newborn', 'Intraoperative Period', 'Male', 'Manometry', 'Methods', 'Monitoring, Physiologic', 'Postoperative Period'] | 2,732,871 | [['M01.060.406'], ['M01.060.406.448'], ['A03.556.875.500'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.703'], ['M01.060.703.520'], ['E04.614.374', 'N02.421.585.753.374'], ['E05.559'], ['E05.581'], ['E01.370.520'], ['E04.614.750', 'N02.421.585.753.750']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unemployment under the flex job scheme increases the risk of permanent social security benefits. | INTRODUCTION: In Denmark, a flex job scheme was introduced in 1998 in the expectation that more people could remain in the workforce despite a reduced working capacity. The aim of this study was to characterise the group that did not obtain a flex job after having been included in the flex job scheme.MATERIAL AND METHO... | ['Denmark', 'Humans', 'Social Security', 'Unemployment'] | 24,814,586 | [['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.346.506.849', 'N03.219.521.576.823'], ['N01.824.245.850']] | ['Geographicals [Z]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Cerebral FDG-PET scanning abnormalities in optimally treated HIV patients. | BACKGROUND: The long-term neurological consequences of HIV infection and treatment are not yet completely understood. In this study we examined the prevalence of cerebral metabolic abnormalities among a cohort of neurologically intact HIV patients with fully suppressed HIV viral loads. Concomitant analyses of circulati... | ['Adult', 'Aged', 'Brain Mapping', 'Cerebral Cortex', 'Cytokines', 'Female', 'Fluorodeoxyglucose F18', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Positron-Emission Tomography'] | 20,152,054 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D09.254.229.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Interplay Between Cognitive Intelligence, Ability Emotional Intelligence, and Religiosity. | The negative association between cognitive intelligence (CI) and religiosity has been widely studied and is now well documented. In contrast, the role of emotional intelligence (EI) in this context has been poorly investigated thus far. Some available data indicate that EI, unlike CI, correlates positively with religio... | ['Cognition', 'Emotional Intelligence', 'Empathy', 'Humans', 'Religion'] | 31,748,923 | [['F02.463.188'], ['F01.752.543.500'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.844']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tryptophan hydroxylase gene polymorphisms are not associated with suicide. | Several lines of evidence suggest a serotonergic dysfunction involved in the biological susceptibility of suicide. Abnormalities of serotonergic markers such as 5-hydroxyindoleacetic acid and prolactin response to fenfluramine have been demonstrated in suicide subjects. Tryptophan hydroxylase (TPH), the rate-limiting e... | ['Adult', 'Alleles', 'DNA', 'Female', 'Gene Frequency', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Suicide', 'Tryptophan Hydroxylase'] | 11,121,198 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['D13.444.308'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.795'], ['F01.145.126.980.875', 'I01.880.735.856'], ['D08.811.682.690.708.870']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
HNRNPC as a candidate biomarker for chemoresistance in gastric cancer. | Chemoresistance is a major cause of treatment failure and high mortality in advanced gastric cancer (AGC). Currently, the mechanism of chemoresistance remains unclear, and there is no biomarker to accurately predict the efficacy of chemotherapy. In the present study, we established human gastric cancer (GC) cell lines ... | ['Biomarkers, Tumor', 'Cell Line, Tumor', 'Drug Resistance, Neoplasm', 'Fluorouracil', 'Heterogeneous-Nuclear Ribonucleoprotein Group C', 'Humans', 'Stomach Neoplasms'] | 26,453,116 | [['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.984.395'], ['D03.383.742.698.875.404'], ['D12.776.157.725.813.750.200', 'D12.776.664.962.813.750.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of phenolic compounds, antioxidant and anticancer activity of Chrozophora tinctoria accessions collected from different regions of Iran. | The present study was conducted to determine the total phenolics, flavonoids, flavonols, anthocyanin, and carotenoids as well as the antioxidant activity of 10 different Crozophora tinctoria accessions originated from Iran. The highest contents of total phenolics, flavonoids, flavonols, anthocyanin, and carotenoids wer... | ['Antineoplastic Agents', 'Antioxidants', 'Euphorbiaceae', 'HeLa Cells', 'Humans', 'Iran', 'Phenols', 'Plant Extracts'] | 31,495,949 | [['D27.505.954.248'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.650.940.800.575.912.250.859.797.438'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['D02.455.426.559.389.657'], ['D20.215.784.500', 'D26... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Morphological changes in human head hair subjected to various drug testing decontamination strategies. | Morphological changes in hair subjected to decontamination protocols were evaluated by scanning electron microscopy (SEM) as part of the National Laboratory Certification Program's (NLCP) efforts to develop proficiency testing materials in support of Federal Workplace Drug Testing programs. Hair from five different don... | ['Adolescent', 'Adult', 'Buffers', 'Child', 'Decontamination', 'Female', 'Hair', 'Humans', 'Methanol', 'Methylene Chloride', 'Microscopy, Electron, Scanning', 'Solvents', 'Substance Abuse Detection'] | 17,320,324 | [['M01.060.057'], ['M01.060.116'], ['D27.720.470.280'], ['M01.060.406'], ['N06.850.780.325'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.623'], ['D02.455.526.439.642'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D27.720.844'], ['E05.885', 'N06.850.780.500.765']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Retrotransposition of the I factor, a non-long terminal repeat retrotransposon of Drosophila, generates tandem repeats at the 3' end. | Non-long terminal repeat (LTR) retrotransposons or LINEs transpose by reverse transcription of an RNA intermediate and are thought to use the 3' hydroxyl of a chromosomal cleavage to initiate synthesis of the first strand of the cDNA. Many of them terminate in a poly(dA) sequence at the 3' end of the coding strand alth... | ['Animals', 'Base Sequence', 'Drosophila melanogaster', 'Long Interspersed Nucleotide Elements', 'Models, Genetic', 'Mutagenesis, Insertional', 'RNA, Messenger', 'RNA-Directed DNA Polymerase', 'Regulatory Sequences, Nucleic Acid', 'Retroelements', 'Tandem Repeat Sequences', 'Terminal Repeat Sequences'] | 10,871,395 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G02.111.570.080.708.330.800.400', 'G05.360.080.708.330.800.400', 'G05.360.340.024.425.800.400'], ['E05.599.395.397'], ['E05.393.420.601.550', 'G05.365.590.575', 'G05.558.550'], ['D13.444.735.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Relation between the changes in thiamine metabolism and energy processes in erythrocytes of patients with diabetes mellitus and approaches to their correction with drugs]. | Erythrocytes, obtained from blood of 12 patients with diabetes mellitus and of 6 donors, were incubated in isotonic medium at 37 degrees within 180 min. Patterns of thiamin metabolism (activity of transketolase and TDP-effect), of glycolysis (content of glucose, lactate) and of energy metabolism (ATP, ADP, AMP and 2,3-... | ['Adenine', 'Adolescent', 'Adult', 'Diabetes Mellitus', 'Energy Metabolism', 'Erythrocytes', 'Female', 'Glycolysis', 'Humans', 'In Vitro Techniques', 'Insulin', 'Male', 'Middle Aged', 'Thiamine', 'Thiamine Pyrophosphate'] | 3,523,986 | [['D03.633.100.759.138'], ['M01.060.057'], ['M01.060.116'], ['C18.452.394.750', 'C19.246'], ['G03.295'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D06.472.699.587.200.500.625', 'D12... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A specific survival response in dopamine neurons at most risk in Parkinson's disease. | The specific expression of fibroblast growth factor 20 (FGF-20) in the adult substantia nigra and the association between FGF-20 mutations and Parkinson's disease provoked exploration of the function of this growth factor. We show by gain- and loss-of-function in vitro experiments that FGF-20 promotes survival and stim... | ['Animals', 'Cell Survival', 'Cells, Cultured', 'Dopamine', 'Fibroblast Growth Factors', 'Humans', 'Mesencephalon', 'Parkinson Disease', 'Rats', 'Risk', 'Substantia Nigra'] | 16,988,046 | [['B01.050'], ['G04.346'], ['A11.251'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.132.659'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Between the ground- and M-state of bacteriorhodopsin the retinal transition dipole moment tilts out of the plane of the membrane by only 3 degrees. | The orientation of the transition dipole moments in the ground state and the M-intermediate of bacteriorhodopsin were determined by time-resolved and steady-state polarized absorption spectroscopy on samples of oriented immobilized purple membranes. The angle between the transition dipole moment and the membrane normal... | ['Bacteriorhodopsins', 'Energy Transfer', 'Fluorescence Polarization', 'Isomerism', 'Membrane Proteins', 'Protein Conformation', 'Retinaldehyde'] | 1,959,640 | [['D12.776.090.200', 'D12.776.157.530.450.250.875.249', 'D12.776.543.585.450.250.875.249', 'D12.776.752.812.249'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E05.196.712.516.600.390'], ['G02.111.570.685', 'G02.607.445'], ['D12.776.543'], ['G02.111.570.820.709'], ['D02.047.850', 'D02.455.326.271.665.202.495.690', 'D02... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Undiagnosed Obstructive Sleep Apnea as Predictor of 90-Day Readmission for Brain Tumor Patients. | BACKGROUND: Previously undiagnosed obstructive sleep apnea (OSA) is a known contributor to negative postoperative outcomes. The STOP-Bang questionnaire is a screening tool for OSA that has been validated in both medical and surgical populations. The authors have previously studied this screening tool in a brain tumor p... | ['Aged', 'Brain Neoplasms', 'Emergency Service, Hospital', 'Female', 'Humans', 'Logistic Models', 'Male', 'Mass Screening', 'Middle Aged', 'Neurosurgical Procedures', 'Patient Readmission', 'ROC Curve', 'Reoperation', 'Sleep Apnea, Obstructive'] | 31,734,423 | [['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.5... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization and regulation of the receptor tyrosine kinase Tie-1 in platelets. | The receptor tyrosine kinase Tie-1 is expressed predominantly on endothelial cells where it has an essential role in blood vessel formation. Targeted disruption of the Tie-1 gene results in a lethal phenotype with severe disruption to the normal integrity of the vasculature. In an examination of Tie-1 in vivo, we obser... | ['Adenosine Diphosphate', 'Adult', 'Blood Platelets', 'Blotting, Western', 'Cells, Cultured', 'Endothelium, Vascular', 'Humans', 'Molecular Weight', 'Neovascularization, Physiologic', 'Organ Specificity', 'Platelet Activation', 'Protease Inhibitors', 'Protein Structure, Tertiary', 'Receptor Protein-Tyrosine Kinases', '... | 11,146,396 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.116'], ['A11.118.188', 'A15.145.229.188'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Phosphoinositide content in the erythrocyte membrane of rats with spontaneous and renal hypertension. | The increase of the content of triphosphoinositide in the erythrocyte membrane in rats with spontaneous and renal hypertension and decrease of phosphatidylinositol at spontaneous hypertension were revealed. | ['Animals', 'Erythrocyte Membrane', 'Erythrocytes', 'Hypertension, Renal', 'Phosphatidylinositols', 'Rats'] | 207,558 | [['B01.050'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['D10.570.755.375.760.400.942'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-coronary cardiac manifestations of systemic lupus erythematosus in adults: a comparative study. | Cardiac manifestations develop in the majority of patients with systemic lupus erythematosus (SLE) at some time during the course of their disease. This study was designed to assess cardiac abnormalities in patients with SLE by echocardiography and to compare the 2 groups of patients with and without cardiac manifestat... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Echocardiography', 'Female', 'Heart Diseases', 'Heart Valve Diseases', 'Hospitals, Military', 'Humans', 'Hypertension, Pulmonary', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Pericardial Effusion', 'Pleural Effusion', 'Tunisia'] | 31,565,118 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280'], ['C14.280.484'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evaluation of Mercury Contamination in Fungi Boletus Species from Latosols, Lateritic Red Earths, and Red and Yellow Earths in the Circum-Pacific Mercuriferous Belt of Southwestern China. | For the first time, highly elevated levels of mercury (Hg) have been documented for several species of the edible Fungi genus Boletus growing in latosols, lateritic red earths, and red and yellow earths from the Yunnan province of China. Analysis of Hg concentrations in the genus suggests that geogenic Hg is the domina... | ['Basidiomycota', 'China', 'Environmental Monitoring', 'Food Contamination', 'Fruiting Bodies, Fungal', 'Mercury', 'Soil', 'Soil Pollutants'] | 26,606,425 | [['B01.300.179'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['A19.374'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Thalamic afferents to the anterior and middle suprasylvian gyri in the cat traced with horseradish peroxidase. | The anatomical organization of thalamic projections to the anterior and middle suprasylvian gyri in the cat has been studied by retrograde axonal transport of horseradish peroxidase. Area 5 receives a large number of fibers from the posterior lateral nucleus, and a few fibers from the dorsal lateral nucleus. It receive... | ['Afferent Pathways', 'Animals', 'Cats', 'Cerebral Cortex', 'Horseradish Peroxidase', 'Nerve Fibers', 'Neurons', 'Somatosensory Cortex', 'Thalamic Nuclei'] | 6,886,388 | [['A08.612.220'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.500'], ['D08.811.682.732.512'], ['A08.675.542', 'A11.671.501'], ['A08.675', 'A11.671'], ['A08.186.211.200.885.287.500.670.675', 'A08.186.211.200.885.287.500.814.906'], ['A08.186.211.200.317.826.701']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiologically guided percutaneous fine-needle aspiration biopsy of pelvic and retroperitoneal masses: a retrospective study of 68 cases. | Fine-needle aspiration (FNA) of the pelvis and retroperitoneum (excluding the pancreas, kidney, and adrenal masses) has not achieved its full potential as a diagnostic modality. We reviewed 68 percutaneous, radiologically guided FNAs from these locations to assess the clinical utility and complication rate of this proc... | ['Biopsy, Needle', 'Humans', 'Lymphoma', 'Melanoma', 'Pelvic Neoplasms', 'Pelvis', 'Retroperitoneal Neoplasms', 'Retroperitoneal Space', 'Retrospective Studies', 'Sarcoma'] | 11,466,812 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['C04.557.465.625.650.510', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Changes of ROS during a two-day ultra-marathon race. | To assess oxidative stress (OS) induced by endurance exercise, concentrations of serum reactive oxygen species (ROS) were determined in 70 Japanese male amateur runners completing a two-day ultra-marathon race. Serum ROS levels were analyzed at three time points: before the race (baseline), after the 1st day race (mid-... | ['Adult', 'Age Factors', 'Athletic Performance', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Oxidative Stress', 'Physical Endurance', 'Reactive Oxygen Species', 'Running'] | 19,199,215 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['I03.450.642.845.054'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['G03.673', 'G07.775.750'], ['G11.427.680', 'I03.450.642.845.054.600'], ['D01.339.431', 'D01.650.775'], ['G11.427.410.568.610', 'G1... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Radiotherapy in the elderly with lung carcinoma: the experience of the Italian "Geriatric Radiation Oncology Group". | One hundred ninety-six patients aged > or = 70 years, with non small-cell lung carcinoma and no evidence of metastasis on staging, observed over a 6-month period in 20 Italian Radiotherapy Centers, were analyzed in order to assess indications for treatment, tolerance of radiotherapy (assessed in terms of completion of ... | ['Age Factors', 'Aged', 'Carcinoma, Non-Small-Cell Lung', 'Humans', 'Lung Neoplasms', 'Palliative Care'] | 9,250,017 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E02.760.666', 'N02.421.585.666']] | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of Korean ginseng berry extract (GB0710) on penile erection: evidence from in vitro and in vivo studies. | Several reports have promoted the root-derived Korean red ginseng (KRG; Panax ginseng) as alternative treatment for erectile dysfunction (ED), and ginsenosides are known to be the principal active ingredients of ginseng. Recent studies showed that ginseng berries produce more ginsenosides than KRG; thus, we investigate... | ['Animals', 'Dose-Response Relationship, Drug', 'Endothelial Cells', 'Enzyme Inhibitors', 'Fruit', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'In Vitro Techniques', 'Male', 'Muscle, Smooth', 'Nitric Oxide', 'Panax', 'Penile Erection', 'Plant Extracts', 'Plant Roots', 'Rabbits', 'Rats', 'Rats, Sprague-Dawley', ... | 23,708,462 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436.275'], ['D27.505.519.389'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A02.633.570', 'A10.690.467'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Long-read sequencing and haplotype linkage analysis enabled preimplantation genetic testing for patients carrying pathogenic inversions. | BACKGROUND: Preimplantation genetic testing (PGT) has already been applied in patients known to carry chromosomal structural variants to improve the clinical outcome of assisted reproduction. However, conventional molecular techniques are not capable of reliably distinguishing embryos that carry balanced inversion from... | ['Adult', 'Aneuploidy', 'Chromosome Inversion', 'Embryo Transfer', 'Female', 'Genetic Linkage', 'Genetic Testing', 'Haplotypes', 'Humans', 'Karyotype', 'Karyotyping', 'Polymorphism, Single Nucleotide', 'Pregnancy', 'Preimplantation Diagnosis'] | 31,439,719 | [['M01.060.116'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['E02.875.800.500', 'E05.820.800.500'], ['G05.348'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['G05.380.3... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells. | The bis-sulfamoylated derivative of 2-methoxyestradiol (2-MeOE2), 2-methoxyestradiol-3,17-O,O-bis-sulfamate (2-MeOE2bisMATE), has shown potent antiproliferative and antiangiogenic activity in vitro and inhibits tumor growth in vivo. 2-MeOE2bisMATE is bioavailable, in contrast to 2-MeOE2 that has poor bioavailability. I... | ['17-Hydroxysteroid Dehydrogenases', '2-Methoxyestradiol', 'Biotransformation', 'Breast Neoplasms', 'Cell Growth Processes', 'Cell Line, Tumor', 'Estradiol', 'Humans', 'Stereoisomerism', 'Transfection'] | 16,397,246 | [['D08.811.682.047.436.375'], ['D04.210.500.365.415.248.830', 'D06.472.334.851.437.500.750'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['C04.588.180', 'C17.800.090.500'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anxiolytic and antidepressant-like activity of a standardized extract from Galphimia glauca. | An infusion prepared with aerial parts from Galphimia glauca has been widely used in Mexican traditional medicine as a remedy for nervous excitement. The sedative activity of a methanolic extract from this plant has been demonstrated by neuropharmacological tests. This effect was attributed to the nor-secotriterpene na... | ['Animals', 'Anti-Anxiety Agents', 'Antidepressive Agents', 'Dose-Response Relationship, Drug', 'Galphimia', 'Male', 'Medicine, Traditional', 'Mexico', 'Mice', 'Mice, Inbred ICR', 'Plant Components, Aerial', 'Plant Extracts'] | 16,360,929 | [['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D27.505.954.427.700.122'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.650.940.800.575.912.250.859.797.690.355'], ['E02.190.488', 'I01.076.201.450.654'], ['Z01.107.567.589'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Advanced medical video services through context-aware medical networks. | The aim of this paper is to present a framework for advanced medical video delivery services, through network and patient-state awareness. Under this scope a context-aware medical networking platform is described. The developed platform enables proper medical video data coding and transmission according to both a) netw... | ['Algorithms', 'Computer Communication Networks', 'Data Compression', 'Information Dissemination', 'Signal Processing, Computer-Assisted', 'Telemedicine', 'Video Recording', 'Videoconferencing'] | 18,002,643 | [['G17.035', 'L01.224.050'], ['L01.224.230.110'], ['L01.224.308.189', 'L01.224.800.500', 'L01.470.500'], ['L01.143.443'], ['L01.224.800'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800'], ['L01.280.960'], ['L01.178.847.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
A Clinical Prediction Tool Identifies Cases of Eosinophilic Esophagitis Without Endoscopic Biopsy: A Prospective Study. | OBJECTIVES: Eosinophilic esophagitis (EoE) is difficult to distinguish from gastroesophageal reflux (GERD) and other causes of dysphagia. We assessed the utility of a set of clinical and endoscopic features for predicting EoE without obtaining esophageal biopsies.METHODS: We prospectively enrolled consecutive adults un... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biopsy', 'Diagnosis, Differential', 'Eosinophilic Esophagitis', 'Esophagoscopy', 'Esophagus', 'Female', 'Follow-Up Studies', 'Gastroesophageal Reflux', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prospective Studies', 'ROC Curve', 'Reproducibility... | 26,303,128 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['C06.405.117.620.209', 'C06.405.205.663.209', 'C15.378.553.231.341', 'C20.543.480.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An alternative dressing material for the split-thickness skin graft donor site: oxidized regenerated cellulose. | The split-thickness skin graft (STSG) donor sites have been treated with various and plenty of dressing techniques and materials. An ideal STSG donor site dressing should have antibacterial, hemostatic, and promoting epidermal healing properties. We have performed a prospective study to evaluate the effect of the oxidi... | ['Absorption', 'Adolescent', 'Adult', 'Aged', 'Bandages', 'Cellulose, Oxidized', 'Child', 'Dermatologic Surgical Procedures', 'Emollients', 'Epithelium', 'Female', 'Guided Tissue Regeneration', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Skin Transplantation', 'Surgical Mesh', 'Surgical Sponges', 'Surgical... | 16,799,310 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.101'], ['D05.750.078.562.180.200', 'D09.698.365.180.200'], ['M01.060.406'], ['E04.680.275'], ['D27.505.954.444.200'], ['A10.272'], ['E04.680.300'], ['B01.050.150.900.649.313.988.400.112.400... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes. | Over the past several years, a great deal of interest has been focused on the harmful effects of ultraviolet (UV) radiation to human skin. UV light has been implicated in aging, sunburn and skin cancer. Few studies, however, have been done to determine the effects that UV light, in conjunction with other environmental ... | ['Cell Line', 'Cell Proliferation', 'Humans', 'Keratinocytes', 'Pyrenes', 'Thymidine', 'Ultraviolet Rays'] | 16,708,424 | [['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A11.436.397'], ['D02.455.426.559.847.799', 'D04.615.799'], ['D03.383.742.680.705', 'D13.570.230.855', 'D13.570.685.705'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of methods of assessment of renal function in patients with cancer treated with cisplatin, carboplatin or methotrexate. | In patients with cancer treated with cisplatin, carboplatin or methotrexate creatinine clearance calculated using the Cockcroft-Gault formula was compared with measured clearance and with the glomerular filtration rate. In 106 patients the average squared difference for calculated and 24 hour urine creatinine clearance... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carboplatin', 'Cisplatin', 'Creatinine', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney', 'Kidney Function Tests', 'Male', 'Metabolic Clearance Rate', 'Methotrexate', 'Middle Aged', 'Neoplasms', 'Technetium Tc 99m Pentetate'] | 2,285,382 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.257.125'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D03.383.129.308.207'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E01.370.390.400'], ['E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Failure of alkaline diuresis to enhance diflunisal elimination. | 1 The effects of alkaline diuresis on the elimination of a single oral dose of 750 mg diflunisal were studied in six healthy male volunteers. 2 The plasma concentrations and half-life of diflunisal were not reduced by alkaline diuresis. 3 The 72 h urinary recovery of unchanged diflunisal was more than doubled with alka... | ['Adult', 'Bicarbonates', 'Diflunisal', 'Diuresis', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Metabolic Clearance Rate', 'Salicylates'] | 7,426,277 | [['M01.060.116'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D02.455.426.559.389.657.410.595.303'], ['G08.852.179'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['D02.241.223.100.300.595', 'D02.241.511.390.595'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parkinsonian syndrome complicating systemic lupus erythematosus. | Two girls with florid extrapyramidal parkinsonism complicating systemic lupus erythematosus (SLE) are reported. One patient (15 years old) presented with extreme rigidity, irritability, and mutism initially diagnosed as acute psychosis. Examination revealed severe extrapyramidal akinetic mutism, along with marked restl... | ['Adolescent', 'Akinetic Mutism', 'Antiparkinson Agents', 'Basal Ganglia', 'Electroencephalography', 'Female', 'Follow-Up Studies', 'Humans', 'Lupus Erythematosus, Systemic', 'Parkinson Disease, Secondary', 'Tomography, Emission-Computed, Single-Photon'] | 9,650,692 | [['M01.060.057'], ['C10.228.140.042'], ['D27.505.954.427.090.050'], ['A08.186.211.200.885.287.249'], ['E01.370.376.300', 'E01.370.405.245'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['C10.2... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phospholipase C activity in rat kidney. Effect of deoxycholate on phosphatidylinositol turnover. | Rat renal cortical and medullary slices incorporate [14C]arachidonate into phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol and triacylglycerols. The percent distribution of [14C]arachidonate among the various phospholipids is similar in renal cortex and medulla, although the total amount of radioact... | ['Animals', 'Arachidonic Acid', 'Arachidonic Acids', 'Deoxycholic Acid', 'In Vitro Techniques', 'Kidney', 'Kidney Cortex', 'Kidney Medulla', 'Kinetics', 'Male', 'Phosphatidylinositols', 'Phospholipases', 'Phospholipids', 'Rats', 'Rats, Inbred Strains'] | 6,810,947 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['D04.210.500.105.225.272', 'D04.210.500.221.430.342'], ['E05.481'], ['A05.810.453'], ['A05.810.453.324'], ['A05.810.453.466'], ['G01.374.661', 'G02.111.490'], ['D10.570.755.375.760.400.942'], ['D08.811... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reversible and irreversible effects of basic peptides on the mitochondrial cationic channel. | We have previously shown that a 13-residue basic peptide, derived from the presequence of a mitochondrial precursor, blocked the cationic channel of the outer mitochondrial membrane. The properties of the blockade suggested that the peptide could go through the pore in the presence of a sufficient driving force. In an ... | ['Adrenal Cortex', 'Amino Acid Sequence', 'Animals', 'Antithrombin III', 'Cattle', 'Electron Transport Complex IV', 'Intracellular Membranes', 'Ion Channels', 'Kinetics', 'Lipid Bilayers', 'Membrane Potentials', 'Mitochondria', 'Molecular Sequence Data', 'Oligopeptides', 'Ornithine-Oxo-Acid Transaminase', 'Peptide Frag... | 7,521,225 | [['A06.300.071.140'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['B01.050.150.900.649.313.500.380.271'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Functional reconstruction of urinary bladder exstrophy: long-term follow-up of urinary continence]. | The author followed up a group of seven patients 5 to 29 years after functional reconstruction without augmentation on account of classical exstrophy of the urinary bladder. The plastic operation to ensure continence was performed in 5 boys and 2 girls at the age of two and a half to 23 months, in six cases by the Youn... | ['Bladder Exstrophy', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Urination'] | 8,488,425 | [['C12.706.132', 'C12.777.829.132', 'C13.351.875.132', 'C13.351.968.829.132', 'C16.131.939.132'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G08.852.880']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Insurance Churning Rates For Low-Income Adults Under Health Reform: Lower Than Expected But Still Harmful For Many. | Changes in insurance coverage over time, or "churning," may have adverse consequences, but there has been little evidence on churning since implementation of the major coverage expansions in the Affordable Care Act (ACA) in 2014. We explored the frequency and implications of churning through surveying 3,011 low-income ... | ['Adult', 'Eligibility Determination', 'Female', 'Health Care Reform', 'Health Insurance Exchanges', 'Humans', 'Insurance Coverage', 'Insurance, Health', 'Male', 'Medicaid', 'Middle Aged', 'Patient Protection and Affordable Care Act', 'Poverty', 'Surveys and Questionnaires', 'United States'] | 27,702,954 | [['M01.060.116'], ['N04.452.264'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['N03.219.521.576.343.918.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.265'], ['N03.219.521.576.343'], ['N03.219.521.346... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Self-derogation and adjustment in the community: a longitudinal study of psychiatric patients. | The authors assessed the symptoms and role performance of a group of psychiatric inpatients 1 year after their discharge to determine their level of adjustment in the community. Level of self-derogation at the time of discharge was consistently found to predict the level of adjustment. The occurrence of stressful life ... | ['Follow-Up Studies', 'Humans', 'Life Change Events', 'Longitudinal Studies', 'Male', 'Mental Disorders', 'Outcome and Process Assessment, Health Care', 'Patient Discharge', 'Personality Inventory', 'Probability', 'Role', 'Self Concept', 'Social Adjustment', 'Social Alienation'] | 4,073,308 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['F03'], ['N04.761.559', 'N05.715.360.575'], ['E02.760.169.125', 'E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
IgG and IgA in saliva and blood serum in relation to smoking and respiratory symptoms. | The main purpose of the paper was to find a possible relationship between smoking and immunological disorders, which are to be the common ground for chronic respiratory diseases. Measurements of IgG and IgA in saliva and blood serum were performed in 87 persons during medical check-up before admission to work in a sulp... | ['Adult', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulins', 'Male', 'Middle Aged', 'Respiratory Tract Diseases', 'Saliva', 'Smoking'] | 549,178 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Super-atmospheric pressure electrospray ion source: applied to aqueous solution. | This is a follow-up paper of our previous report on an ion source, which was operated at an operating pressure higher than the atmospheric pressure. Besides having more working gas for desolvation, the reduction of mean free path of electrons in a higher pressure environment increases the threshold voltage for gaseous ... | ['Animals', 'Atmospheric Pressure', 'Cattle', 'Equipment Design', 'Proteins', 'Solutions', 'Spectrometry, Mass, Electrospray Ionization', 'Vacuum', 'Water'] | 21,989,705 | [['B01.050'], ['G16.500.750.274', 'N06.230.300.100.185'], ['B01.050.150.900.649.313.500.380.271'], ['E05.320'], ['D12.776'], ['D26.776'], ['E05.196.566.600'], ['G01.374.715.902', 'G16.500.750.274.902', 'N06.230.300.100.185.902'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effects of needle type, gauge, and tip bend on spinal needle deflection. | Although the use of fine-gauge spinal needles reduces the incidence of postdural puncture headache, they are associated with increased risk of placement failure as a result of deflection and bending. This in vitro study quantifies spinal needle deflection from the axis of insertion with respect to needle type, gauge, a... | ['Animals', 'In Vitro Techniques', 'Muscles', 'Needles', 'Spinal Puncture', 'Swine'] | 8,561,330 | [['B01.050'], ['E05.481'], ['A02.633', 'A10.690'], ['E07.612'], ['E01.370.225.998.054.790', 'E01.370.376.700', 'E02.800.779', 'E04.074.790', 'E04.665.700', 'E05.200.998.054.790'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Performance Evaluation of a Genotypic Tropism Test Using HIV-1 CRF01_AE Isolates in Japan. | Geno2Pheno (coreceptor), a genotypic tropism test, demonstrates excellent agreement with the phenotypic tropism test for subtype B and some other subtypes. However, potential X4-overcalling for CRF01_AE might occur with the present version. To confirm X4 overcalling for AE and to optimize the algorithm for use with AE,... | ['Diagnostic Errors', 'Genotype', 'Genotyping Techniques', 'HIV-1', 'Humans', 'Japan', 'Microbiological Techniques', 'Phenotype', 'Sequence Analysis, DNA', 'Viral Tropism', 'env Gene Products, Human Immunodeficiency Virus'] | 29,709,982 | [['E01.354', 'N02.421.450.280'], ['G05.380'], ['E05.393.442'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E01.370.225.875', 'E05.200.875'], ['G05.695'], ['E05.393.760.700'], ['G06.099.925', 'G06.920.863'], ['D12.776.964.775.325.164', 'D12.776.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A pilot study of the noninvasive assessment of the lung microbiota as a potential tool for the early diagnosis of ventilator-associated pneumonia. | BACKGROUND: Ventilator-associated pneumonia (VAP) remains a common complication in critically ill surgical patients, and its diagnosis remains problematic. Exhaled breath contains aerosolized droplets that reflect the lung microbiota. We hypothesized that exhaled breath condensate fluid (EBCF) in hygroscopic condenser ... | ['Bronchoalveolar Lavage', 'Critical Illness', 'DNA, Bacterial', 'Diagnostic Tests, Routine', 'Exhalation', 'Humans', 'Intensive Care Units', 'Lung', 'Microbiological Techniques', 'Microbiota', 'Pilot Projects', 'Pneumonia, Ventilator-Associated', 'Real-Time Polymerase Chain Reaction', 'Regression Analysis', 'Sensitivi... | 25,474,571 | [['E05.927.100'], ['C23.550.291.625'], ['D13.444.308.212'], ['E01.370.395'], ['G09.772.705.700.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['A04.411'], ['E01.370.225.875', 'E05.200.875'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['E05.318.372.750', 'E05.337... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhanced cecropin B2 production via chitin-binding domain and intein self-cleavage system. | In this study, various constructs and hosts were used to produce high levels of cecropin B2 (cecB2). To mitigate cecB2's toxic inhibition of host cells, various cecB2 constructs were built. Results showed that the combination of a chitin-binding domain and an intein self-cleavage motif in front of cecropin B2, without ... | ['Acinetobacter baumannii', 'Antimicrobial Cationic Peptides', 'Escherichia coli', 'Insect Proteins', 'Recombinant Fusion Proteins', 'Staphylococcus aureus'] | 30,471,160 | [['B03.440.400.425.537.050.099', 'B03.660.250.530.050.099'], ['D12.644.050', 'D12.776.543.695.054'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.093.500'], ['D12.776.828.300'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Noninvasive coronary angiography with electron beam tomography: methods and clinical evaluation in post-PTCA follow-up]. | Electron beam tomography (EBT) is a computed tomography technique with unique spatial and temporal resolution. The aim of the study was to establish and evaluate a protocol for the non-invasive visualization and detection of stenoses of the coronary arteries. Following phantom studies, 103 patients were investigated. A... | ['Adult', 'Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Coronary Disease', 'Equipment Design', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Middle Aged', 'Phantoms, Imaging', 'Recurrence', 'Sensitivity and Specificity', 'Technology Assessment, Biomedical', 'Tomography, X-Ray ... | 9,173,696 | [['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Kinetic Cooperativity in Human Pancreatic Glucokinase Originates from Millisecond Dynamics of the Small Domain. | The hallmark of glucokinase (GCK), which catalyzes the phosphorylation of glucose during glycolysis, is its kinetic cooperativity, whose understanding at atomic detail has remained open since its discovery over 40 years ago. Herein, by using kinetic CPMG NMR spectroscopic data for 17 isoleucine side chains distributed ... | ['Catalysis', 'Glucokinase', 'Humans', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Pancreas', 'Phosphorylation'] | 26,013,420 | [['G02.130'], ['D08.811.913.696.620.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['E05.599.595'], ['A03.734'], ['G02.111.665', 'G02.607.780', 'G03.796']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson's disease. | The origin and tissue distribution of the mitochondrial dysfunction in Parkinson's disease (PD) remains still a matter of controversy. To re-evaluate a probably free radical-born, generalized mitochondrial impairment in PD, we applied optimized enzymatic assays, high resolution oxygraphic measurements of permeabilized ... | ['Adult', 'Aged', 'Cell Respiration', 'DNA Mutational Analysis', 'DNA, Mitochondrial', 'Electron Transport', 'Female', 'Free Radicals', 'Humans', 'Male', 'Middle Aged', 'Mitochondria', 'Mitochondrial Diseases', 'Muscle, Skeletal', 'Oxidative Phosphorylation', 'Oxidative Stress', 'Parkinson Disease', 'Point Mutation'] | 15,340,872 | [['M01.060.116'], ['M01.060.116.100'], ['G03.197', 'G04.270'], ['E05.393.760.700.300'], ['D13.444.308.283.225'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D01.339', 'D02.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['C18.452.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Considering planetary environments in origin of life studies. | Early Earth geological conditions would have affected prebiotic chemistry: particularly the lack of atmospheric oxygen, presence of dissolved iron, and increased high-energy radiation. Incorporating planetary conditions into origin-of-life studies can also advance our search for life on other worlds. | ['Air', 'Atmosphere', 'Cosmic Radiation', 'Earth, Planet', 'Ecosystem', 'Evolution, Chemical', 'Origin of Life', 'Water'] | 30,538,232 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['G16.500.275.063', 'N06.230.300.100'], ['G01.060.185', 'G01.750.750.235', 'G16.500.200', 'N06.230.300.100.300'], ['G01.060.075.730.700.200'], ['G16.500.275.157', 'N06.230.124'], ['G01.060.275.500', 'G02.225'], ['G16.650', 'I01.076.368.584.542'], ['D01.045.250.875', 'D01... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Considerations on treatment efficiency of different conformal radiation therapy techniques for prostate cancer. | BACKGROUND AND PURPOSE: To evaluate the treatment efficiency of different conformal radiation therapy techniques in prostate cancer.MATERIALS AND METHODS: Three major classes of intensity-modulated radiation therapy (IMRT) delivery as well as a conformal rotation technique have been evaluated: sequential tomotherapy, d... | ['Humans', 'Male', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Radiotherapy, Conformal', 'Rectum', 'Urinary Bladder'] | 12,065,100 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.639'], ['E02.815.635.700', 'L01.313.500.750.100.710.600.550'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['A05.810.890']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging. | BACKGROUND: The mitochondria are essential organelles and are the location of cellular respiration, which is responsible for the majority of ATP production. Each cell contains multiple mitochondria, and each mitochondrion contains multiple copies of its own circular genome. The ratio of mitochondrial genomes to nuclear... | ['Aged', 'Aging', 'Amino Acid Sequence', 'Animals', 'DNA Copy Number Variations', 'DNA, Mitochondrial', 'Electron Transport Complex IV', 'Female', 'Genetic Variation', 'Genome, Mitochondrial', 'Haplotypes', 'Humans', 'Longevity', 'Male', 'Mitochondria', 'Molecular Sequence Data', 'Sequence Alignment'] | 25,077,862 | [['M01.060.116.100'], ['G07.345.124'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G05.365.795.297.500'], ['D13.444.308.283.225'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['G05.365'], ['G05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Management of multiple sequelaes in permanent dentition: 3 years follow-up. | A 12-year-old patient with multiple sequelaes of permanent dentition due to trauma in primary dentition at the age of 8 months, is presented. Clinical and radiographical examinations revealed aesthetical defects, crown-root malformations (#21), hypoplasia (#12, #22), tooth transposition (#13) and odontoma-like malforma... | ['Child', 'Child, Preschool', 'Dental Restoration, Permanent', 'Dentition, Permanent', 'Female', 'Follow-Up Studies', 'Humans', 'Incisor', 'Infant', 'Odontoma', 'Radiography', 'Tooth Abnormalities', 'Tooth Avulsion', 'Tooth Crown', 'Tooth Injuries', 'Tooth Root', 'Tooth, Deciduous', 'Treatment Outcome'] | 21,244,630 | [['M01.060.406'], ['M01.060.406.448'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['A14.549.167.237'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860.425'], ['M01.060.703'], ['C04.557.695.610'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anaesthesia for caesarean section in a patient with Sturge-Weber syndrome following acute neurological deterioration. | Sturge-Weber syndrome consists of facial capillary malformation (port-wine stain) and abnormal blood vessels in the brain or eye. Seizures, developmental delay and intracranial and airway angiomata are principal concerns. We report a 28-year-old primiparous woman at 41 weeks of gestation with Sturge-Weber syndrome who ... | ['Adult', 'Anesthesia, Epidural', 'Anesthesia, Obstetrical', 'Brain', 'Cesarean Section', 'Female', 'Humans', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Nervous System Diseases', 'Pregnancy', 'Sturge-Weber Syndrome', 'Treatment Failure'] | 21,315,576 | [['M01.060.116'], ['E03.155.086.131'], ['E03.155.364'], ['A08.186.211'], ['E04.520.252.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.350.825.500'], ['C10'], ['G08.686.784.769'], ['C04.557.645.375.850', 'C10.562.800', 'C14.907.077.850'], ['E01.789.800.760', 'N04.761.559.590.800.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of elevated carbon dioxide and ozone on the foliar nonvolatile terpenoids in ginkgo biloba. | The aim of this study was to determine the effects of elevated O(3) and elevated CO(2,) singly and in combination, on the contents of nonvolatile terpenoids in leaves of Ginkgo Biloba. The results showed that elevated CO(2), alone and in combination with elevated O(3) increased concentrations of all the determined terp... | ['Atmosphere Exposure Chambers', 'Carbon Dioxide', 'Chromatography, High Pressure Liquid', 'Ginkgo biloba', 'Greenhouse Effect', 'Ozone', 'Plant Leaves', 'Spectrometry, Mass, Electrospray Ionization', 'Terpenes'] | 18,626,560 | [['E07.079'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.196.181.400.300'], ['B01.650.940.800.575.912.125'], ['G16.500.175.827', 'N06.230.265'], ['D01.362.670.600'], ['A18.024.812'], ['E05.196.566.600'], ['D02.455.849']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Urinary macrophage migration inhibitory factor in children with urinary tract infection. | Macrophage migration inhibitory factor (MIF) plays an essential pathophysiological role in inflammatory reactions. The aim of this study was to investigate the clinical utility of urine MIF (uMIF) level in predicting urinary tract infections (UTI). This multicenter, prospective study was conducted over a 1-year period ... | ['Area Under Curve', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Macrophage Migration-Inhibitory Factors', 'Male', 'Predictive Value of Tests', 'Prospective Studies', 'ROC Curve', 'Urinalysis', 'Urinary Tract Infections'] | 19,841,948 | [['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D12.644.276.374.480.625', 'D12.776.467.374.480.625', 'D23.125.477.500', 'D23.529.374.480.625'], ['E05.318.370.800.650', 'N05.715.360.32... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Population pharmacokinetic and pharmacodynamic analysis for time courses of docetaxel-induced neutropenia in Japanese cancer patients. | The present study describes a population pharmacokinetic and pharmacodynamic (PK/PD) analysis based on data obtained from cancer patients treated with docetaxel at the National Cancer Center Hospital East in Japan. Docetaxel was infused intravenously over 1 h every 3 weeks, and time courses of absolute neutrophil count... | ['Adult', 'Antineoplastic Agents', 'Docetaxel', 'Humans', 'Infusions, Intravenous', 'Japan', 'Kinetics', 'Models, Biological', 'Neoplasms', 'Neutropenia', 'Reproducibility of Results', 'Taxoids'] | 17,888,031 | [['M01.060.116'], ['D27.505.954.248'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['Z01.252.474.463', 'Z01.639.595'], ['G01.374.661', 'G02.111.490'], ['E05.599.395'], ['C04'], ['C15.378.553.546.184.564'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Microwave-assisted efficient preparation of novel carbohydrate tetrazole derivatives. | A series of novel N-1, N-2 and S-5 saccharide substituted tetrazole derivatives linked at anomeric and nonanomeric positions were obtained from commercial tetrazoles under microwave irradiation. Yields are compared with conventional methodologies. | ['Carbohydrate Conformation', 'Carbohydrates', 'Disaccharides', 'Microwaves', 'Models, Molecular', 'Molecular Conformation', 'Optical Rotation', 'Tetrazoles'] | 17,359,951 | [['G02.111.570.820.235'], ['D09'], ['D09.698.629.305', 'D09.947.750'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['E05.599.595'], ['G02.111.570.820'], ['G01.590.773'], ['D03.383.129.617']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pretreatment risk management of a novel nomogram model for prediction of thoracoabdominal extrahepatic metastasis in primary hepatic carcinoma. | BACKGROUND: Extrahepatic metastasis is the independent risk factor of poor survival of primary hepatic carcinoma (PHC), and most occurs in the chest and abdomen. Currently, there is still no available method to predict thoracoabdominal extrahepatic metastasis in PHC. In this study, a novel nomogram model was developed ... | ['Algorithms', 'Calibration', 'Clinical Decision-Making', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Models, Biological', 'Neoplasm Metastasis', 'Nomograms', 'Prognosis', 'ROC Curve', 'Risk Factors', 'Risk Management'] | 30,961,629 | [['G17.035', 'L01.224.050'], ['E05.978.155'], ['E01.055'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E05.599.395'], ['C04.697.650', 'C23.550.727.650'], ['E01.789.650', 'E05.318.740.500.625', 'E05.599.835.895', 'G17.582', 'N05.715.360.750.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
On the norming of homophones. | Associative norms for homographs have been widely used in the study of language processing. A number of sets of these are available, providing the investigator with the opportunity to compare materials collected over a span of years and a range of locations. Words that are homophonic but not homographic have been used ... | ['Acoustic Stimulation', 'Adult', 'Comprehension', 'Humans', 'Language Tests', 'Linguistics', 'Phonetics', 'Reading', 'Recognition, Psychology', 'Reference Standards', 'Reference Values', 'Vocabulary', 'Word Association Tests'] | 18,522,063 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['F02.463.188.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['L01.559.598'], ['L01.559.598.518'], ['L01.559.423.557'], ['F02.463.425.540.706'], ['E05.978.808'], ['E05.978.810'], ['L01.559.598.901'], ['F04.711.647.905']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Pilot electromyographic studies of resting oral activity in obese and normal subjects. | Subjects were placed alone in a room where purposeful oral activity such as eating, talking and smoking was not permitted, while activity such as pursing the lips sucking on cheeks, grimaces etc was measured by a specially designed electromyometer. This was done via electrodes attached to the peri-oral area and was rec... | ['Adult', 'Cues', 'Electromyography', 'Facial Muscles', 'Feeding Behavior', 'Female', 'Humans', 'Middle Aged', 'Mouth', 'Obesity', 'Periodicity', 'Reading', 'Stress, Psychological'] | 528,132 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Telomere length and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies. | The aim of the present study was to map and grade evidence for the relationships between telomere length with a diverse range of health outcomes, using an umbrella review of systematic reviews with meta-analyses. We searched for meta-analyses of observational studies reporting on the association of telomere length with... | ['Alzheimer Disease', 'Case-Control Studies', 'Diabetes Mellitus', 'Humans', 'Incidence', 'Observational Studies as Topic', 'Stomach Neoplasms', 'Telomere', 'Treatment Outcome'] | 30,776,454 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.3... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response. | Although there is evidence that redox regulation has an essential role in malignancies, its impact on tumor prognosis remains unclear. Here we show crosstalk between oxidative stress and the miR-200 family of microRNAs that affects tumorigenesis and chemosensitivity. miR-141 and miR-200a target p38á and modulate the ox... | ['Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Carcinoma, Ovarian Epithelial', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Transformation, Neoplastic', 'Down-Regulation', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice', 'Mice, Nude', 'MicroRNAs', 'Middle Aged', ... | 22,101,765 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['C04.557.470.200.295', 'C04.588.322.455.199', 'C13.351.500.056.630.705.350', 'C13.351.937.418.685.350', 'C19.344.410.199', 'C19.391.630.705.350'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.697.098.5... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genotyping of hepatitis B virus in Malaysia based on the nucleotide sequence of preS and S genes. | Hepatitis B virus (HBV) has been classified into eight genotypes, designated A-H. These genotypes are known to have distinct geographic distributions. The clinical importance of genotype-related differences in the pathogenicity of HBV has been revealed recently. In Malaysia, the current distribution of HBV remains uncl... | ['Amino Acid Sequence', 'Carrier State', 'DNA, Viral', 'Genotype', 'Hepatitis B Surface Antigens', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Malaysia', 'Molecular Sequence Data', 'Protein Precursors'] | 15,792,534 | [['G02.111.570.060', 'L01.453.245.667.060'], ['N06.850.520.169'], ['D13.444.308.568'], ['G05.380'], ['D23.050.327.495.500.475'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Coexistent intraventricular abnormalities in periventricular giant arachnoid cysts. | OBJECT: Arachnoid cysts are congenital lesions that arise during development by splitting of the arachnoid membrane. Large cysts can be adjacent to CSF pathways causing a marked midline shift and hydrocephalus. The association between a large arachnoid cyst and hydrocephalus has been commonly described as being due to ... | ['Adolescent', 'Arachnoid Cysts', 'Cerebral Aqueduct', 'Cerebral Ventricles', 'Child', 'Endoscopy', 'Female', 'Humans', 'Hydrocephalus', 'Male', 'Young Adult'] | 19,338,470 | [['M01.060.057'], ['C04.182.044', 'C04.588.614.250.387.100', 'C10.500.142.100', 'C10.551.240.375.100', 'C16.131.666.142.100'], ['A08.186.211.132.659.413.875.187', 'A08.186.211.140.187'], ['A08.186.211.140'], ['M01.060.406'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The glial drug methionine sulfoximine reduces goldthioglucose lesions in mice. | A toxic form of glucose, goldthioglucose (GTG), damages the arcuate nucleus and nucleus of the solitary tract (NTS) after passage through permeable circumventricular capillaries in adjacent structures, but the mechanism of action is unclear. To see if GTG initially acts upon glia to cause lesions, adult male mice were ... | ['Animals', 'Arcuate Nucleus of Hypothalamus', 'Aurothioglucose', 'Glycogen', 'Gold', 'Histocytochemistry', 'Iron', 'Male', 'Medulla Oblongata', 'Methionine Sulfoximine', 'Mice', 'Neuroglia'] | 2,507,091 | [['B01.050'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['D02.691.675.249'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Tubal plastic surgery at the Tel Hashomer Hospital: a critical study. | The study presents 93 patients in whom tubal surgery was carried out for primary or secondary mechanical infertility. A classification of these patients into five groups is suggested. Twenty-four uterine pregnancies were recorded, eighteen of which reached term. A plea for enlarging the scope and number of intervention... | ['Abortion, Incomplete', 'Adult', 'Aftercare', 'Fallopian Tubes', 'Female', 'Humans', 'Infertility, Female', 'Methods', 'Pregnancy', 'Pregnancy, Ectopic', 'Retrospective Studies'] | 179,897 | [['C13.703.039.093'], ['M01.060.116'], ['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['A05.360.319.114.373', 'A13.706.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['E05.581'], ['G08.686.784.769'], ['C13.703.733'], ['E05.318.372.500.500.500', 'E05.318.372.500.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Perioperative stroke effectively treated by an acute stroke team including anesthesia department: a case report]. | Perioperative stroke is cerebral infarction occurring in the perioperative period. The incidence of perioperative stroke in non-cardiac, and non-neurologic surgery is about 0.7%, but the mortality can be as high as 26% to 40%. The outcome of the patients with perioperative stroke can be disastrous. Here we report a cas... | ['Aged', 'Anesthesia Department, Hospital', 'Angiography, Digital Subtraction', 'Female', 'Humans', 'Middle Cerebral Artery', 'Patient Care Team', 'Stents', 'Stroke', 'Treatment Outcome'] | 29,263,488 | [['M01.060.116.100'], ['N02.278.216.500.968.070', 'N04.452.442.452.422.070'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.228.550'], ['N04.590.715'], ['E07.695.750'], [... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Changes of nitric oxide and endothelin serum level after carotid balloon denudation or stent assisted angioplasty: an experimental and clinical observation]. | OBJECTIVE: To observe the changes of nitric oxide (NO) and endothelin (ET) serum level in the Guangxi BA-MA minipigs whose carotid arteries were injured by balloon denudation and in the patients with carotid stent assisted angioplasty.METHODS: Twelve Guangxi BA-MA minipigs were chosen. High fat/cholesterol feeding and ... | ['Aged', 'Angioplasty, Balloon', 'Animals', 'Carotid Arteries', 'Carotid Stenosis', 'Disease Models, Animal', 'Endothelins', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nitric Oxide', 'Postoperative Period', 'Random Allocation', 'Stents', 'Swine', 'Swine, Miniature'] | 19,595,226 | [['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['B01.050'], ['A07.015.114.186'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MicroRNA expressions associated with progression of prostate cancer cells to antiandrogen therapy resistance. | BACKGROUND: Development of resistance to androgen deprivation therapy (ADT) is a major obstacle for the management of advanced prostate cancer. Therapies with androgen receptor (AR) antagonists and androgen withdrawal initially regress tumors but development of compensatory mechanisms including AR bypass signaling lead... | ['Androgen Antagonists', 'Anilides', 'Cell Line, Tumor', 'Cluster Analysis', 'Drug Resistance, Neoplasm', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'MicroRNAs', 'Nitriles', 'Prostatic Neoplasms', 'Tosyl Compounds', 'Transcriptome'] | 24,387,052 | [['D06.347.065', 'D27.505.696.399.450.065'], ['D02.065.199', 'D02.092.146.113'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G07.690.773.984.395'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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