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Infection with flaviviruses requires BCLXL for cell survival. | BCL2 family proteins including pro-survival proteins, BH3-only proteins and BAX/BAK proteins control mitochondria-mediated apoptosis to maintain cell homeostasis via the removal of damaged cells and pathogen-infected cells. In this study, we examined the roles of BCL2 proteins in the induction of apoptosis in cells upo... | ['Animals', 'Apoptosis', 'Cell Line', 'Cell Survival', 'Chlorocebus aethiops', 'Dengue Virus', 'Encephalitis Virus, Japanese', 'Flavivirus', 'Flavivirus Infections', 'Gene Knockout Techniques', 'HEK293 Cells', 'Host-Pathogen Interactions', 'Humans', 'Immunity, Innate', 'Mice', 'Mice, Knockout', 'Models, Biological', 'M... | 30,261,081 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['B04.820.578.344.350.270'], ['B04.820.230.475.227', 'B04.820.578.344.350.300.227'], ['B04.820.578.344.350'], ['C01.925.782.350.250'], ['E05.393.335.750'], ['A11.251.210.172.750', 'A11.436.334'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of phytosterols in dietary diacylglycerol on atherosclerosis in cholesterol-fed rabbits. | OBJECTIVE: The present study investigated the effects of phytosterols (PS) in combination with diacylglycerol (DAG) versus PS in combination with triacylglycerol (TAG) on serum lipids and atherosclerosis in cholesterol-fed rabbits.METHODS: Cholesterol-fed (0.3%) New Zealand white rabbits were treated with a control die... | ['Animals', 'Aorta', 'Aorta, Thoracic', 'Arteriosclerosis', 'Cholesterol', 'Cholesterol, Dietary', 'Diglycerides', 'Male', 'Phytosterols', 'Rabbits', 'Random Allocation', 'Triglycerides'] | 12,831,957 | [['B01.050'], ['A07.015.114.056'], ['A07.015.114.056.372'], ['C14.907.137.126'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['D10.351.303'], ['D04.210.500.247.808.756', 'D10.570.938.795', 'D23.704.500'], ['B01.050... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Gender related differences on the EEG during a simulated mobile phone signal. | The present study investigated the gender-related influence of electromagnetic fields (EMF), similar to that emitted by mobile phones, on brain activity. Ten women and nine men performed a short memory task (Wechsler test), both without (baseline) and with exposure to a 900 MHz signal. The EEG energy of the total wavef... | ['Adult', 'Brain', 'Brain Mapping', 'Cell Phone', 'Computer Simulation', 'Electrodes', 'Electroencephalography', 'Electromagnetic Fields', 'Female', 'Humans', 'Male', 'Multivariate Analysis', 'Sex Characteristics', 'Time Factors'] | 15,538,195 | [['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['L01.178.847.698.300'], ['L01.224.160'], ['E07.305.250'], ['E01.370.376.300', 'E01.370.405.245'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500'... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Ankle motor skill is intact in spinal cord injury, unlike stroke: implications for rehabilitation. | BACKGROUND: After an incomplete spinal cord injury (iSCI) or stroke, the impairment of both muscle strength and accurate muscle coordination (timing and amplitude) is an expected clinical finding, although these aspects are not well-distinguished by clinical tests. The objective was to determine whether iSCI patients w... | ['Adult', 'Aged', 'Aged, 80 and over', 'Disability Evaluation', 'Extremities', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Middle Aged', 'Motor Cortex', 'Motor Skills', 'Movement Disorders', 'Muscle Strength', 'Muscle Weakness', 'Muscle, Skeletal', 'Neuropsychological Tests', 'Paresis', 'Pyramidal Tracts', 'S... | 20,404,308 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.400'], ['A01.378'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['F02.808.260'], ['C10.228.662'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of causal relations between haemodynamic variables, auditory evoked potentials and isoflurane by means of fuzzy logic. | The aim of this study was to identify a possible relationship between haemodynamic variables, auditory evoked potentials (AEP) and inspired fraction of isoflurane (ISOFl). Two different models (isoflurane and mean arterial pressure) were identified using the fuzzy inductive reasoning (FIR) methodology. A fuzzy model is... | ['Anesthetics, Inhalation', 'Evoked Potentials, Auditory', 'Female', 'Fuzzy Logic', 'Hemodynamics', 'Humans', 'Hysterectomy', 'Isoflurane', 'Models, Biological', 'Monitoring, Intraoperative'] | 10,325,831 | [['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['D02.355.601.570'], ['E05.599.395'], ['E0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Gene loss and evolutionary rates following whole-genome duplication in teleost fishes. | Teleost fishes provide the first unambiguous support for ancient whole-genome duplication in an animal lineage. Studies in yeast or plants have shown that the effects of such duplications can be mediated by a complex pattern of gene retention and changes in evolutionary pressure. To explore such patterns in fishes, we ... | ['Animals', 'Chromosomes', 'Evolution, Molecular', 'Fish Proteins', 'Fishes', 'Gene Deletion', 'Gene Duplication', 'Genome', 'Phylogeny', 'Polyploidy'] | 16,809,621 | [['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['G05.045.250', 'G16.075.250'], ['D12.776.325'], ['B01.050.150.900.493'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.365.590.320', 'G05.558.320'], ['G05.360.340'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['C23.550.210.702', 'G05.365.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Dependence of electrical activity of the amygdaloid complex on level of motivation and emotional state of the dog. | The effect of an increment in the power of the rhythmic activity of the amygdala during changes in the level of motivation in conditions of the dominance of alimentary or defensive motivation, irrespective of type, was discovered on the basis of spectral analysis of prolonged recordings of electrosubcorticograms of the... | ['Amygdala', 'Animals', 'Conditioning, Classical', 'Dogs', 'Electric Stimulation', 'Electrodes', 'Electroencephalography', 'Electrophysiology', 'Emotions', 'Motivation', 'Skin Physiological Phenomena'] | 2,096,322 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['F02.463.425.179.308'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.723.402'], ['E07.305.250'], ['E01.370.376.300', 'E01.370.405.245'], ['H01.158.344.528', 'H01.158.782.236'], ['F01.470'], ['F01.658', 'F01.752.543.500.750'], ['G13.750']] | ['Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Flavobacterium dankookense sp. nov., isolated from a freshwater reservoir, and emended descriptions of Flavobacterium cheonanense, F. chungnamense, F. koreense and F. aquatile. | A novel yellow-pigmented bacterial strain, designated ARSA-19(T), was isolated from a freshwater reservoir in Cheonan, Korea. Cells were Gram-staining-negative, rod-shaped, strictly aerobic and positive for catalase and oxidase. The phylogenetic tree based on 16S rRNA gene sequences showed that strain ARSA-19(T) belong... | ['Bacterial Typing Techniques', 'Base Composition', 'DNA, Bacterial', 'Flavobacterium', 'Fresh Water', 'Korea', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Vitamin K 2'] | 22,140,162 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['D13.444.308.212'], ['B03.440.080.190.250', 'B03.440.400.425.310.250'], ['G16.500.275.280', 'N06.230.232'], ['Z01.252.474.557', 'Z01.586.407'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['E05.393.760.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Microtubule-associated protein 1A is a modifier of tubby hearing (moth1). | Once a mutation in the gene tub was identified as the cause of obesity, retinal degeneration and hearing loss in tubby mice, it became increasingly evident that the members of the tub gene family (tulps) influence maintenance and function of the neuronal cell lineage. Suggested molecular functions of tubby-like protein... | ['Adaptor Proteins, Signal Transducing', 'Alleles', 'Animals', 'Cell Line', 'Cloning, Molecular', 'DNA, Complementary', 'Disks Large Homolog 4 Protein', 'Gene Library', 'Genetic Markers', 'Guanylate Kinases', 'Immunoblotting', 'Insulin', 'Intracellular Signaling Peptides and Proteins', 'Membrane Proteins', 'Mice', 'Mic... | 11,925,566 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G05.360.340.024.340.030'], ['B01.050'], ['A11.251.210'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D08.811.913.696.650.450.750', 'D12.644.360.265', 'D12.776.476.265', 'D12.776.543.219', 'D12.776.631.224... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gender differences are associated with the clinical features of systemic lupus erythematosus. | BACKGROUND: Systemic lupus erythematosus (SLE) mostly occurred in young women. This study was undertaken to investigate the different clinical characteristics of SLE between male and female patients, and to identify the sex hormone levels and clinical outcomes of different gender in SLE patients.METHODS: Of the 516 SLE... | ['Adult', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Retrospective Studies', 'Risk Factors', 'Sex Factors'] | 22,882,925 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['E05.318.740.600.800.725', 'N05.715.350.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors Associated With Opioid Use in Patients Hospitalized for Acute Pancreatitis. | Importance: Limited guidance exists regarding the optimal approach to management of pain in acute pancreatitis (AP).Objectives: To investigate sources of variability in opioid use for treatment of acute pain in patients hospitalized for AP and to explore a potential association of opioid prescribing patterns with lengt... | ['Acute Disease', 'Adult', 'Aged', 'Aged, 80 and over', 'Analgesics, Opioid', 'Cohort Studies', 'Delivery of Health Care, Integrated', 'Female', 'Hospitalization', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Opioid-Related Disorders', 'Pain Management', 'Pancreatitis', 'Patient Discharge', 'Predictive Value of ... | 30,977,846 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N04.590.374.142', 'N05.300.2... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Neuropeptide Y-induced pressor responses: activation of a non-adrenergic mechanism, potentiation by reserpine and blockade by nifedipine. | Intravenous administration of neuropeptide Y (NPY) to pentobarbital anesthetized rats produced a short-lasting concentration-dependent increase in systolic and diastolic blood pressure. Pretreatment of rats with 2 mg/kg reserpine potentiated the NPY-induced pressor responses causing a leftward shift of the NPY concentr... | ['Angiotensin II', 'Animals', 'Blood Pressure', 'Drug Synergism', 'Ion Channels', 'Male', 'Nerve Tissue Proteins', 'Neuropeptide Y', 'Nifedipine', 'Norepinephrine', 'Phenoxybenzamine', 'Rats', 'Rats, Inbred Strains', 'Reserpine', 'Tyramine'] | 2,414,116 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.968.477'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D12.776.631'], ['D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Puberty in the male chimpanzee: time-related variations in circulating inhibin. | Circulating immunoreactive inhibin concentrations were determined in male chimpanzees (n = 12) during a 36-mo period starting 18 mo before the onset of pubertal testicular growth (Po). Serum levels of inhibin started to increase, together with LH and testosterone, 6 mo before a rise in FSH and Po. Before Po, inhibin wa... | ['Animals', 'Feedback', 'Follicle Stimulating Hormone', 'Inhibins', 'Luteinizing Hormone', 'Male', 'Pan troglodytes', 'Sexual Maturation', 'Testis', 'Testosterone', 'Time Factors'] | 8,452,924 | [['B01.050'], ['L01.906.394.211'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.334.968', 'D06.472.699.337', 'D12.644.548.387', 'D12.776.395.439'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Aminergic neurons: state control and plasticity in three model systems. | Aminergic neurons have particular functions in many systems, and in this review their role is discussed and compared in three systems: those parts of the central nervous system controlling sleep and waking in the cut; the superior cervical ganglion: and the isolated nervous system of Aplysia. In the cat the aminergic n... | ['Animals', 'Behavior', 'Brain Stem', 'Cats', 'Cyclic AMP', 'Interneurons', 'Learning', 'Models, Neurological', 'Neuronal Plasticity', 'Neurons', 'Rabbits', 'Sleep', 'Sleep, REM', 'Wakefulness'] | 6,286,127 | [['B01.050'], ['F01.145'], ['A08.186.211.132'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A08.675.358', 'A11.671.358'], ['F02.463.425', 'F02.784.629.529'], ['E05.599.395.642'], ['G11.561.638'], ['A08.675', 'A11.67... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rupture fo the intestine in patients with hernia. | Two cases of perforation of the small intestine associated with minor abdominal trauma and right inguinal hernia are presented along with a review of 104 cases in the literature, The condition is treacherous because this minimal injury can produce catastrophic intraabdominal perforation. The most reliable signs and sym... | ['Abdominal Injuries', 'Adult', 'Colon', 'Hernia, Inguinal', 'Humans', 'Ileum', 'Intestinal Perforation', 'Jejunum', 'Male', 'Middle Aged', 'Pressure', 'Rupture, Spontaneous'] | 1,124,411 | [['C26.017'], ['M01.060.116'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['C06.405.469.557'], ['A03.556.124.684.500', 'A03.556.249.750'], ['M01.060.116.630'], ['G01.374.715'], ['C23.300.909']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The X linked recessive form of XY gonadal dysgenesis with a high incidence of gonadal germ cell tumours: clinical and genetic studies. | Five phenotypic females in one family had the genotype 46,XY and all had gonadal germ cell tumours. Studies of the family pedigree suggest that this form of XY gonadal dysgenesis is inherited in an X linked recessive manner. G banding of elongated metaphase chromosomes from two subjects with XY gonadal dysgenesis and a... | ['Adolescent', 'Chromosome Banding', 'Dermatoglyphics', 'Female', 'Genes, Recessive', 'Genetic Linkage', 'Gonadal Dysgenesis', 'Gonadal Dysgenesis, 46,XY', 'Humans', 'Ovarian Neoplasms', 'Pedigree', 'Phenotype', 'Teratoma', 'X Chromosome'] | 6,620,326 | [['M01.060.057'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['E05.318.740.225.500.375', 'I01.198.780.937.343', 'N04.452.910.099.500'], ['G05.360.340.024.340... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Design and evaluation of hydraulic baffled-channel PAC contactor for taste and odor removal from drinking water supplies. | Based on the concept of hydraulic flocculator, a baffled-channel powdered activated carbon (PAC) contactor, placed before the rapid-mixing basin, was designed and evaluated for removal of taste and odor (T&O) in drinking water. PAC adsorption kinetic tests for raw water samples were conducted for selection of design pa... | ['Adsorption', 'Drinking', 'Humans', 'Korea', 'Odorants', 'Pilot Projects', 'Smell', 'Taste', 'Water Purification', 'Water Supply'] | 17,400,274 | [['G01.030', 'G02.020'], ['G07.203.650.283.249', 'G10.261.330.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.557', 'Z01.586.407'], ['G16.500.275.640', 'N06.230.480'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['F02.830.816.643', 'G11.561.790.643'], ['F02.83... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
A fast model independent method for automatic correction of intensity nonuniformity in MRI data. | A novel nonparametric approach for correcting intensity nonuniformity in magnetic resonance (MR) images is described. This approach is based solely on the assumption that the various sources of nonuniformity in MR imaging give rise to smooth variations in image intensity, and that these variations can be extracted and ... | ['Algorithms', 'Brain', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Phantoms, Imaging'] | 10,508,322 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['E07.671']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Expression of chemokine receptors CXCR4, CXCR5 and CCR7 on B and T lymphocytes from patients with primary antibody deficiency. | The interaction of chemokines and their receptors directs lymphocyte migration, and is involved in the distribution and organization of lymphocytes within lymphoid tissues. We reasoned that abnormal chemokine receptor expression might give rise to defects of lymphocyte migration into and within lymphoid tissues, and co... | ['Adult', 'B-Lymphocytes', 'Case-Control Studies', 'Common Variable Immunodeficiency', 'Female', 'Flow Cytometry', 'Humans', 'Immunologic Deficiency Syndromes', 'Immunologic Memory', 'Male', 'Middle Aged', 'Receptors, CCR7', 'Receptors, CXCR4', 'Receptors, CXCR5', 'Receptors, Chemokine', 'Statistics, Nonparametric', 'T... | 19,250,276 | [['M01.060.116'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C20.673.330'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350',... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic complementation of Agrobacterium tumefaciens Ti plasmid mutants in the virulence region. | Mutants with Tn5 insertions in the vir region of the Agrobacterium tumefaciens TiC58 plasmid are unable to form crown-gall tumors. Complementation tests of these vir region mutants were carried out by constructing merodiploids in a recombination-deficient strain. Each merodiploid possessed a mutant TiC58 plasmid and a ... | ['Cloning, Molecular', 'DNA Restriction Enzymes', 'Escherichia coli', 'Genetic Complementation Test', 'Mutation', 'Plant Tumors', 'Plasmids', 'Rhizobium', 'Species Specificity', 'Virulence'] | 6,318,043 | [['E05.393.220'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.393.281.526'], ['G05.365.590'], ['G15.610.700'], ['G05.360.600'], ['B03.440.400.425.700.800', 'B03.585.900', 'B03.660.050.662.670'], ['G16.824'], ['G06.930']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mouse immune interferon (IFN-gamma) gene is on chromosome 10. | A cDNA clone for mouse immune interferon has been used to map the mouse interferon gamma gene (Ifg) to a specific chromosome. This clone, which contains a 638-bp insert detects an 18-kb HindIII fragment of mouse DNA. The presence of the mouse Ifg gene in cel hybrids and its chromosomal location were determined by assay... | ['Animals', 'Cell Line', 'Chromosome Mapping', 'Cloning, Molecular', 'Cricetinae', 'Cricetulus', 'DNA', 'Genes', 'Hybrid Cells', 'Interferon-gamma', 'Lymphocytes', 'Mice', 'Mice, Inbred BALB C', 'Nucleic Acid Hybridization'] | 6,433,489 | [['B01.050'], ['A11.251.210'], ['E05.393.183'], ['E05.393.220'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D13.444.308'], ['G05.360.340.024.340'], ['A11.251.600'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New knowledge derived from learned knowledge: functional-anatomic correlates of stimulus equivalence. | Forming new knowledge based on knowledge established through prior learning is a central feature of higher cognition that is captured in research on stimulus equivalence (SE). Numerous SE investigations show that reinforcing behavior under control of distinct sets of arbitrary conditional relations gives rise to stimul... | ['Adolescent', 'Adult', 'Brain', 'Cognition', 'Female', 'Humans', 'Learning', 'Magnetic Resonance Imaging', 'Male', 'Memory', 'Middle Aged', 'Psychomotor Performance', 'Visual Perception'] | 17,465,317 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['E01.370.350.825.500'], ['F02.463.425.540'], ['M01.060.116.630'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.463.593.932']] | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diurnal blood pressure variability in essential hypertension and vascular reactivity to isometric stress. | The present study was designed to assess the hemodynamic conditions, by means of impedance cardiography methods, and the relation existing between vascular reactivity to isometric stress (isometric handgrip test) and the day/night blood pressure variations, estimated by ABPM. Fifty unselected untreated non-obese EEH ad... | ['Adult', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Circadian Rhythm', 'Exercise', 'Female', 'Humans', 'Hypertension', 'Male', 'Retrospective Studies', 'Stress, Physiological'] | 7,623,369 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['G07.180.562.190'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cytotoxicity of new resin-, calcium hydroxide- and silicone-based root canal sealers on fibroblasts derived from human gingiva and L929 cell lines. | AIM: To assess ex vivo the cytotoxic effects of five new root canal sealers (RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal) and three existing products (AH Plus, RoekoSeal and Apexit) using primary human gingival fibroblasts (HGF) and a mouse fibroblast cell line, L929.METHODOLOGY: Eight samples of each sealer w... | ['Animals', 'Calcium Hydroxide', 'Cell Line', 'Fibroblasts', 'Gingiva', 'Humans', 'Mice', 'Resin Cements', 'Root Canal Filling Materials', 'Silicon'] | 17,309,743 | [['B01.050'], ['D01.045.250.313', 'D01.146.335', 'D01.248.497.158.459.150'], ['A11.251.210'], ['A11.329.228'], ['A14.549.167.646.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.750.716.822.730', 'D25.339.291.750', 'D25.720.716.822.730', 'J01.637.051.339.291.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pulmonary barotrauma: a case report with illustrative radiology. | A case of a 24-year-old gentleman who had pulmonary barotrauma (PBT) after diving is reported. He presented with chest pain after the second of two uneventful shallow SCUBA dives. Computerized tomography (CT) scan confirmed the diagnosis and he was treated conservatively. Relevant radiology and a discussion of PBT are ... | ['Barotrauma', 'Diving', 'Humans', 'Lung Injury', 'Male', 'Pneumothorax', 'Subcutaneous Emphysema', 'Young Adult'] | 32,187,620 | [['C26.120'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.520', 'C26.891.554'], ['C08.528.778'], ['C23.550.325.500'], ['M01.060.116.815']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Accelerated reabsorption in the proximal tubule produced by volume depletion. | The renal response to chronic depletion of extracellular volume was examined using the techniques of micropuncture. Depletion of salt and water was produced by administration of furosemide to rats maintained on a sodium-free diet. There was a marked fall in body weight, plasma volume, and glomerular filtration rate. Th... | ['Aldosterone', 'Animals', 'Autoradiography', 'Body Weight', 'Diet, Sodium-Restricted', 'Extracellular Space', 'Furosemide', 'Glomerular Filtration Rate', 'Inulin', 'Kidney Concentrating Ability', 'Kidney Tubules', 'Male', 'Microsurgery', 'Plasma Volume', 'Punctures', 'Rats', 'Sodium', 'Tritium', 'Water-Electrolyte Bal... | 5,090,054 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E02.642.249.290', 'G07.203.650.240.290'], ['A10.082.500', 'A11.284.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feasibility Study of Extended-Gate-Type Silicon Nanowire Field-Effect Transistors for Neural Recording. | In this research, a high performance silicon nanowire field-effect transistor (transconductance as high as 34 µS and sensitivity as 84 nS/mV) is extensively studied and directly compared with planar passive microelectrode arrays for neural recording application. Electrical and electrochemical characteristics are carefu... | ['Feasibility Studies', 'Nanowires', 'Signal-To-Noise Ratio', 'Silicon', 'Transistors, Electronic'] | 28,350,370 | [['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['J01.637.512.925'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750'], ['D01.268.513.937'], ['E07.305.625.714']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A Kaposi's sarcoma-associated herpesvirus protein that forms inhibitory complexes with type I interferon receptor subunits, Jak and STAT proteins, and blocks interferon-mediated signal transduction. | Type I interferons (IFNs) are important mediators of innate antiviral defense and function by activating a signaling pathway through their cognate type I receptor (IFNAR). Here we report that lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV) efficiently blocks type I IFN signaling and that an importan... | ['Base Sequence', 'HeLa Cells', 'Herpesviridae Infections', 'Herpesvirus 8, Human', 'Humans', 'Interferon Type I', 'Interferon-Stimulated Gene Factor 3, gamma Subunit', 'Janus Kinase 1', 'Molecular Sequence Data', 'Open Reading Frames', 'Phosphorylation', 'Receptor, Interferon alpha-beta', 'STAT1 Transcription Factor',... | 19,279,093 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['C01.925.256.466'], ['B04.280.210.400.700.330', 'B04.280.382.400.700.330', 'B04.613.204.500.700.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890', 'D12.776.467.374... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cortical Superficial Siderosis in Memory Clinic Patients: Further Evidence for Underlying Cerebral Amyloid Angiopathy. | BACKGROUND: Cerebral amyloid angiopathy (CAA) is associated with many cases of spontaneous symptomatic lobar intracerebral haemorrhage in older individuals and is emerging as an important contributor to cognitive impairment. Cortical superficial siderosis (cSS) is an increasingly recognized haemorrhagic neuroimaging ma... | ['Aged', 'Alzheimer Disease', 'Cerebral Amyloid Angiopathy', 'Cerebral Hemorrhage', 'Cohort Studies', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Memory', 'Neuroimaging'] | 26,751,369 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C10.228.140.300.510.200.200', 'C14.907.253.560.200.200', 'C18.452.845.500.100'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750']... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Out-of-hospital intravenous cannulation: the perspective of patients treated by London Ambulance Service paramedics. | OBJECTIVES: Previous research has highlighted concern about infection rates in field-placed intravenous (IV) cannulae. In a study of IV placement by London Ambulance Service (LAS) paramedics, 17% of placements were judged to be inappropriate. Large variations in rates of IV placement between LAS paramedics were found. ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Allied Health Personnel', 'Ambulances', 'Catheterization, Peripheral', 'Chi-Square Distribution', 'Direct Service Costs', 'Female', 'Humans', 'Infusions, Intravenous', 'London', 'Male', 'Middle Aged', 'Pain', 'Patient Satisfaction', 'Retrospective Studies', 'Surveys... | 10,691,070 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.526.485.067', 'N02.360.067'], ['J01.937.500.050', 'N02.421.297.879.100'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.99... | ['Named Groups [M]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Specific release of a 9-kDa extrinsic polypeptide of photosystem I from spinach chloroplasts by salt washing. | The newly reported 9-kDa polypeptide in photosystem I [(1991) FEBS Lett. 280, 332-334] is an extrinsic component located on the lumenal side of the thylakoid membrane. This subunit can be solubilized with high salt buffer and does not bind any cofactors. The photosystem I electron transfer chain remains intact and func... | ['Amino Acid Sequence', 'Chloroplasts', 'Electron Transport', 'Intracellular Membranes', 'Membrane Proteins', 'Molecular Sequence Data', 'NADP', 'Photosynthetic Reaction Center Complex Proteins', 'Photosystem I Protein Complex', 'Plant Proteins', 'Plants', 'Plastocyanin'] | 1,505,669 | [['G02.111.570.060', 'L01.453.245.667.060'], ['A11.284.430.214.190.875.700.140'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['A11.284.149.450', 'A11.284.835.514'], ['D12.776.543'], ['L01.453.245.667'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['D05.500.562.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants. | Trypsin, porcine pancreatic kallikrein, and several blood coagulation enzymes, including bovine thrombin, bovine factor Xa, human factor Xa, human plasma factor XIa, human plasma factor XIIa, and human plasma kallikrein, were inactivated by a number of substituted isocoumarins containing basic functional groups (aminoa... | ['Animals', 'Anticoagulants', 'Blood Coagulation Factors', 'Cattle', 'Coumarins', 'Female', 'Humans', 'Kinetics', 'Placenta', 'Pregnancy', 'Prekallikrein', 'Serine Endopeptidases', 'Serine Proteinase Inhibitors', 'Spectrometry, Fluorescence', 'Structure-Activity Relationship', 'Trypsin Inhibitors'] | 3,164,217 | [['B01.050'], ['D27.505.954.502.119'], ['D12.776.124.125', 'D23.119'], ['B01.050.150.900.649.313.500.380.271'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A16.710'], ['G08.686.784.769'], ['D08.622.658', 'D08.811.277.656.300.760.442.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Do biological, sociodemographic, and behavioral characteristics explain racial/ethnic disparities in preterm births? | Many studies find racial/ethnic disparities in a diverse set of birth outcomes. However few empirical studies have examined the existence and possible explanations for racial/ethnic disparities in preterm births using a diverse set of racial/ethnic categories and a nationally representative sample of births. This resea... | ['Chi-Square Distribution', 'Cross-Cultural Comparison', 'European Continental Ancestry Group', 'Female', 'Health Services Accessibility', 'Health Status Disparities', 'Hispanic Americans', 'Humans', 'Indians, North American', 'Infant, Newborn', 'Infant, Premature', 'Logistic Models', 'Longitudinal Studies', 'Male', 'P... | 19,285,373 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['M01.686.508.400'], ['N04.590.374.350', 'N05.300.430'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Re-development of synaptic connections after implanted single 5-HT containing neuron in isolated leech ganglia. | Single mature Retzius cells which contain 5-HT have been implanted in isolated ganglia of Whitmania pigra. The properties of the implanted Retzius cell and its connections with the original identified nerve cells of the ganglia have been measured by intracellular microelectrodes. At 3 days in culture an implanted Retzi... | ['Animals', 'Culture Techniques', 'Electrophysiology', 'Ganglia', 'Leeches', 'Neurons', 'Serotonin', 'Synapses'] | 2,742,751 | [['B01.050'], ['E05.481.500'], ['H01.158.344.528', 'H01.158.782.236'], ['A08.340'], ['B01.050.500.091.426'], ['A08.675', 'A11.671'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650'], ['A08.850', 'A11.284.149.165.420.780']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Diuretic therapy and exercise in patients with systemic hypertension. | Twenty patients with uncomplicated systemic hypertension underwent treadmill testing twice during placebo treatment and twice during hydrochlorothiazide treatment. Data were collected at rest, at peak exercise and 10 min after exercise. Serum potassium, magnesium and plasma catecholamines increased significantly with e... | ['Arrhythmias, Cardiac', 'Cardiomegaly', 'Catecholamines', 'Combined Modality Therapy', 'Double-Blind Method', 'Exercise Therapy', 'Humans', 'Hydrochlorothiazide', 'Hypertension', 'Magnesium', 'Middle Aged', 'Potassium', 'Randomized Controlled Trials as Topic'] | 2,534,412 | [['C14.280.067', 'C23.550.073'], ['C14.280.195', 'C23.300.775.250'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['E02.186'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MAOA genotype influences neural response during an inhibitory task in adolescents with conduct disorder. | Conduct disorder (CD), a common psychiatric disorder in children and adolescents, is characterized by encroaching upon other rights and violations of age-appropriate social expectations repeatedly and persistently. Individuals with CD often have high aggressiveness and low inhibitory capacity. The monoamine oxidase A (... | ['Child', 'Conduct Disorder', 'Female', 'Genotype', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Monoamine Oxidase'] | 29,855,796 | [['M01.060.406'], ['F03.625.094.300'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['D08.811.682.664.750']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. | AIMS: To investigate the role of macrophage migration inhibitory factor (MIF) and its downstream cytokine cascade in necrotizing enterocolitis (NEC).METHODS AND RESULTS: The expression of MIF mRNA and protein in NEC guts was assayed by in situ hybridization and immunohistochemistry, respectively. Concentrations of MIF,... | ['Acute Disease', 'Cells, Cultured', 'Culture Media, Conditioned', 'Enterocolitis, Necrotizing', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Infant, Newborn', 'Interleukin-6', 'Interleukin-8', 'Macrophage Migration-Inhibitory Factors', 'Macrophages', 'RNA, Messenger'... | 15,910,597 | [['C23.550.291.125'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E0... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Crystal structure of the human natural killer cell activating receptor KIR2DS2 (CD158j). | Killer cell Ig-like receptors (KIRs) regulate the function of human natural killer and T cell subsets. A feature of the KIR locus is the clustering of homologous genes encoding for inhibitory and activating KIR. Inhibitory and activating KIR differ for ligand specificities and/or affinities. In particular, we show here... | ['Crystallization', 'HLA-C Antigens', 'Humans', 'Protein Conformation', 'Receptors, Immunologic', 'Receptors, KIR', 'Receptors, KIR2DL2'] | 12,668,644 | [['E05.196.300', 'G02.171'], ['D12.776.395.550.489.600', 'D12.776.543.550.439.600', 'D23.050.301.500.100.600', 'D23.050.301.500.450.390', 'D23.050.705.552.100.600', 'D23.050.705.552.450.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820.709'], ['D12.776.543.750.705'], ['D12.776.543.750.705.895.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deployment of a Short, Single-Opening Endoscopic Clip Versus a Long, Reopening Endoscopic Clip in Clinical Practice. | BACKGROUND: Endoscopic clips vary in their designs and costs. Clip wastage is a common problem, and this is dependent on the success of its deployment.AIMS: The aim of this study is to compare the rates of successful deployment between two different commonly used endoscopic clips.METHODS: A single-center, retrospective... | ['Colonic Polyps', 'Endoscopy', 'Equipment Design', 'Humans', 'Multivariate Analysis', 'Retrospective Studies'] | 25,822,036 | [['C23.300.825.411.235'], ['E01.370.388.250', 'E04.502.250'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fifty-three reoperations for hyperparathyroidism. | Fifty-three patients, 35 with persistent and 7 with recurrent hyperparathyroidism, had parathyroid surgery. There were 11 patients who had prior thyroid surgery before being identified as having hyperparathyroidism. Forty patients had parathyroid adenomas and 13 (8 dialysis patients) had parathyroid hyperplasia. Thalli... | ['Adenoma', 'Humans', 'Hyperparathyroidism', 'Hyperplasia', 'Parathyroid Glands', 'Parathyroid Neoplasms', 'Radiography', 'Radionuclide Imaging', 'Reoperation', 'Thyroidectomy'] | 2,802,046 | [['C04.557.470.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355'], ['C23.550.444'], ['A06.300.560'], ['C04.588.322.525', 'C04.588.443.680', 'C19.344.525', 'C19.642.713'], ['E01.370.350.700'], ['E01.370.350.710', 'E01.370.384.730'], ['E04.690'], ['E04.270.856']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contribution of mucosal maltase-glucoamylase activities to mouse small intestinal starch alpha-glucogenesis. | Digestion of starch requires activities provided by 6 interactive small intestinal enzymes. Two of these are luminal endo-glucosidases named alpha-amylases. Four are exo-glucosidases bound to the luminal surface of enterocytes. These mucosal activities were identified as 4 different maltases. Two maltase activities wer... | ['Acarbose', 'Animals', 'Gene Expression Regulation, Enzymologic', 'Glucose', 'Intestinal Mucosa', 'Isomaltose', 'Jejunum', 'Maltose', 'Mice', 'Mice, Knockout', 'Starch', 'alpha-Glucosidases'] | 17,585,022 | [['D09.698.629.802.100'], ['B01.050'], ['G05.308.320'], ['D09.947.875.359.448'], ['A03.556.124.369', 'A10.615.550.444'], ['D09.698.365.410', 'D09.698.629.305.320', 'D09.947.750.320'], ['A03.556.124.684.500', 'A03.556.249.750'], ['D09.698.365.450', 'D09.698.629.305.523', 'D09.947.750.523'], ['B01.050.150.900.649.313.992... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Framework for integrating indigenous and scientific knowledge for disaster risk reduction. | A growing awareness of the value of indigenous knowledge has prompted calls for its use within disaster risk reduction. The use of indigenous knowledge alongside scientific knowledge is increasingly advocated but there is as yet no clearly developed framework demonstrating how the two may be integrated to reduce commun... | ['Disaster Planning', 'Disasters', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Papua New Guinea', 'Risk Reduction Behavior'] | 19,793,324 | [['N06.230.100.035'], ['N06.230.100'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.590.715'], ['F01.145.699']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The limits of individual identification from sample allele frequencies: theory and statistical analysis. | It was shown recently using experimental data that it is possible under certain conditions to determine whether a person with known genotypes at a number of markers was part of a sample from which only allele frequencies are known. Using population genetic and statistical theory, we show that the power of such identifi... | ['Gene Frequency', 'Genetics, Population', 'Genotype', 'Humans', 'Models, Genetic', 'Models, Statistical', 'Polymorphism, Single Nucleotide'] | 19,798,439 | [['G05.330'], ['H01.158.273.343.335'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G05.365.795.598']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Factors predicting prognosis of epilepsy after presentation with seizures. | The objective of this study was to identify the factors, at the time of diagnosis, that determine the prognosis for remission of epilepsy. A prospective community-based cohort study of 792 patients recruited at the time of their first diagnosis of epileptic seizures was undertaken; in those classified 6 months after pr... | ['Child', 'Child, Preschool', 'Epilepsy', 'Female', 'Humans', 'Infant', 'Male', 'Predictive Value of Tests', 'Prognosis'] | 11,117,539 | [['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E01.789']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mental health and ethnic density among adolescents in England: A cross-sectional study. | This paper determines the association of neighbourhood ethnic density on adolescent mental health and its interplay with ethnic minority status and neighbourhood deprivation. 4145 cross-sectional responses to the 2009-2011 UK Household Longitudinal Study (UKHLS) youth self-completion questionnaire for youths aged 10-15... | ['Adolescent', 'Censuses', 'Child', 'Child Welfare', 'Cross-Sectional Studies', 'England', 'Ethnic Groups', 'European Continental Ancestry Group', 'Family Characteristics', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Mental Health', 'Minority Groups', 'Residence Characteristics', 'Surveys and Questionnaires'] | 31,706,664 | [['M01.060.057'], ['I01.240.205', 'N01.224.175', 'N06.850.505.400.225'], ['M01.060.406'], ['I01.880.787.293'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.363.300'], ['M01.686.754', 'N01.224.317'], ['M01.686.508.400'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Selective occurrence of ras mutations in benign and malignant thyroid follicular neoplasms in Taiwan. | Previous studies have demonstrated that point mutations in all three ras genes (H-ras, K-ras, and N-ras) may occur in thyroid neoplasia. However, the overall incidence of ras mutations in thyroid tumors and their frequency in specific histologic types varies widely in different series. Many earlier studies have chosen ... | ['Adenocarcinoma, Follicular', 'Genes, ras', 'Genetic Testing', 'Humans', 'Point Mutation', 'Polymorphism, Genetic', 'Prevalence', 'Taiwan', 'Thyroid Neoplasms'] | 15,320,975 | [['C04.557.470.200.025.060'], ['G05.360.340.024.340.375.500.791.550'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.675'], ['G05.365.795'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.9... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of intra-arterial vasodilators on blood flow in ischemic dog colon. | The vasodilators papaverine hydrochloride, tolazoline hydrochloride, and isoproterenol hydrochloride were infused into the superior mesenteric artery (SMA) of dogs in which an ischemic Thiry-Vella colon loop had been formed. The washout of an intra-arterial injection of xenon Xe 133 to the normal and ischemic colon seg... | ['Animals', 'Colon', 'Dogs', 'Female', 'Ischemia', 'Isoproterenol', 'Male', 'Mesenteric Arteries', 'Papaverine', 'Pulse', 'Regional Blood Flow', 'Tolazoline', 'Vasodilator Agents'] | 7,377,962 | [['B01.050'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['B01.050.150.900.649.313.750.250.216.200'], ['C23.550.513'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['A07.015.114.565'], ['D03.132.098.666', 'D03.132.577.750', 'D03.633.100.531.085.666'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Presence of cholinergic and calcium channel blocking activities explains the traditional use of Hibiscus rosasinensis in constipation and diarrhoea. | The aqueous-ethanolic extract of the aerial parts of Hibiscus rosasinensis Linn. (Malvaceae) was studied for the possible presence of spasmogenic and spasmolytic constituents to rationalize its traditional use in gastrointestinal disorders. The crude extract (Hr.Cr) caused a concentration-dependent (1-10mg/mL) spasmoge... | ['Acetylcholine', 'Animals', 'Cholinergic Agents', 'Constipation', 'Diarrhea', 'Dose-Response Relationship, Drug', 'Female', 'Guinea Pigs', 'Hibiscus', 'In Vitro Techniques', 'Male', 'Medicine, Traditional', 'Phytotherapy', 'Plant Extracts', 'Rabbits'] | 16,182,481 | [['D02.092.211.111'], ['B01.050'], ['D27.505.519.625.120', 'D27.505.696.577.120'], ['C23.888.821.150'], ['C23.888.821.214'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.550'], ['B01.650.940.800.575.912.250.859.821.500.288'], ['E05.481'], ['E02.190.488', 'I01.076.201.450.654'], ['E02.190.755'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Sickle-cell anaemia: an explanation for the ancient myth of reincarnation in Nigeria. | The belief in reincarnation, widely held in Nigeria for many centuries, has waned in the past 30 years. It is most probable that the "reincarnate" child had sickle-cell anaemia, since this disease would explain all the clinical features and natural history of "reincarnation". Most reincarnate children died of Plasmodiu... | ['Anemia, Sickle Cell', 'Folklore', 'Humans', 'Infant', 'Infant, Newborn', 'Malaria', 'Nigeria'] | 6,136,656 | [['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['I01.076.201.450.515', 'K01.517.455'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C01.610.752.530', 'C01.920.875'], ['Z01.058.290.190.565']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
How well will stacked transgenic pest/herbicide resistances delay pests from evolving resistance? | Resistance has evolved to single transgenic traits engineered into crops for arthropod and herbicide resistances, and can be expected to evolve to the more recently introduced pathogen resistances. Combining transgenes against the same target pest is being promoted as the solution to the problem. This solution will wor... | ['Animals', 'Crops, Agricultural', 'Evolution, Molecular', 'Insecticide Resistance', 'Pest Control, Biological', 'Plants, Genetically Modified', 'Time Factors', 'Transgenes'] | 27,598,030 | [['B01.050'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['G05.045.250', 'G16.075.250'], ['G07.690.773.984.491'], ['N06.850.780.200.650.650'], ['B01.650.520', 'B05.620.600'], ['G01.910.857'], ['G05.360.340.024.340.825']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Regulation of aqueous flow by the adenylate cyclase receptor complex in the ciliary epithelium. | The answer to how the beta-adrenergic receptor mediates a fall in intraocular pressure has been elusive. Methods of measurement have not been refined sufficiently. The separate changes after adrenergic treatment frequently are small, and the tissue effects are multiple. On a molecular basis, stimulation of the beta-adr... | ['ADP-Ribosylation Factors', 'Adenylyl Cyclases', 'Adult', 'Aged', 'Anterior Chamber', 'Aqueous Humor', 'Cell Membrane Permeability', 'Ciliary Body', 'Colforsin', 'Cyclic AMP', 'Diterpenes', 'Epithelium', 'Humans', 'Intraocular Pressure', 'Membrane Proteins', 'Middle Aged', 'Receptors, Adrenergic, beta', 'Timolol'] | 2,990,214 | [['D08.811.277.040.330.300.400.100', 'D12.644.360.525.100', 'D12.776.157.325.515.100', 'D12.776.476.525.100'], ['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['M01.060.116'], ['M01.060.116.100'], ['A09.371.060.067'], ['A09.371.060.067.070', 'A12.207.270.040'], ['G03.143.335', 'G04.175'], ['A09.371.060.1... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Surface smoothing, decimation, and their effects on 3D biological specimens. | OBJECTIVE: Smoothing and decimation filters are commonly used to restore the realistic appearance of virtual biological specimens, but they can cause a loss of topological information of unknown extent. In this study, we analyzed the effect of smoothing and decimation on a 3D mesh to highlight the consequences of an in... | ['Algorithms', 'Animals', 'Anthropology, Physical', 'Anthropometry', 'Imaging, Three-Dimensional', 'Pongo', 'Skull', 'Surface Properties', 'Virtual Reality'] | 29,446,075 | [['G17.035', 'L01.224.050'], ['B01.050'], ['I01.076.368'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.350.400', 'L01.224.308.410'], ['B01.050.150.900.649.313.988.400.112.400.635'], ['A02.835.232.781'], ['G02.860'], ['L01.224.160.875', 'L01.296.555']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Construction of a peptide with an electroactive daunomycin like a pendant arm to detect ovalbumin. | In this study, a peptide-1 (RNRCKGTDVQAW) constructing lysozyme was conjugated with an electroactive daunomycin in order to voltammetrically detect ovalbumin (OVA). Hetero-bifunctional cross-linking agents with four kinds of ethylene chains in differing lengths were used to bind the peptide-1 and daunomycin. After a cr... | ['Animals', 'Cattle', 'Chick Embryo', 'Chickens', 'Cross-Linking Reagents', 'Daunorubicin', 'Egg White', 'Electrochemical Techniques', 'Electrodes', 'Mass Spectrometry', 'Molecular Probe Techniques', 'Molecular Probes', 'Muramidase', 'Ovalbumin', 'Peptides', 'Quail', 'Sensitivity and Specificity', 'Serum'] | 25,604,822 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D27.720.470.410.210'], ['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200', 'D09.408.051.059.200'], ['G07.203.300.470.700', 'J02.500.470.700'], ['E05.301'], ['E0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Methotrexate: studies on cellular metabolism. IV. Effect on the mitochondrial oxidation of cytosolic-reducing equivalents in HeLa cells. | The effect of methotrexate (MTX) on the mitochondrial oxidation of cytosolic-reducing equivalents in HeLa cells was studied. MTX inhibited (100 per cent) malate dehydrogenase activity, but no effect was observed on that of GOT. MTX (0.5 mM) inhibited (100 per cent) the activity of reconstituted enzymatic system MDH-GOT... | ['Arsenic', 'Arsenites', 'Aspartate Aminotransferases', 'Aspartic Acid', 'Cytosol', 'HeLa Cells', 'Humans', 'Malate Dehydrogenase', 'Malates', 'Methotrexate', 'Mitochondria', 'Oxidation-Reduction'] | 2,272,117 | [['D01.268.513.249'], ['D01.075.050', 'D01.248.497.158.055'], ['D08.811.913.477.700.225'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.11... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maximum running speed limitations on terrestrial mammals: a theoretical approach. | Here we study maximum running speed (MRS) limitations on a previously proposed model of energetic and muscle-tendon unit functions on running mammals. In the present work the MRS and some anatomical or physiological limitations are estimated for mammals with body mass between 1.5 and 300 kg. The MRS variations with bod... | ['Animals', 'Body Weight', 'Energy Metabolism', 'Extremities', 'Mammals', 'Models, Biological', 'Muscle Strength', 'Running', 'Tendons'] | 17,196,212 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G03.295'], ['A01.378'], ['B01.050.150.900.649'], ['E05.599.395'], ['E01.370.600.425', 'G11.427.560'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.61... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Replication of human cytomegalovirus in a rhabdomyosarcoma cell line depends on the state of differentiation of the cells. | The replication of human cytomegalovirus (HCMV) was investigated in a new human rhabdomyosarcoma cell line (KFR) with morphological and biochemical characteristics of fetal striated muscle precursors (rhabdomyoblasts). KFR cells exhibited the unique property for spontaneous morphological transformation from a poorly-di... | ['Antigens, Viral', 'Base Sequence', 'Cell Differentiation', 'Cytomegalovirus', 'Humans', 'Immediate-Early Proteins', 'Molecular Sequence Data', 'Muscle, Skeletal', 'Rhabdomyosarcoma', 'Tumor Cells, Cultured', 'Viral Proteins', 'Virus Replication'] | 7,998,845 | [['D23.050.327'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.152'], ['B04.280.382.150.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.460', 'D12.776.964.925.968'], ['L01.453.245.667'], ['A02.633.567', 'A10.690.552.500'], ['C04.557.450.590.550.660', 'C04.557.450.795.550.660'], ['A... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Blood levels of glial fibrillary acidic protein (GFAP) in patients with neurological diseases. | BACKGROUND AND PURPOSE: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke. Comparably little, however, is known about GFAP release in other neurological disorders. In order to identify potential "specific... | ['Adult', 'Aged', 'Biomarkers', 'Cerebral Hemorrhage', 'Female', 'Glial Fibrillary Acidic Protein', 'Humans', 'Ischemic Attack, Transient', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Stroke'] | 23,626,774 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['M01.060.116.630'], ['C10'], ['C10.228.140.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Duodenal perforation as a delayed complication of placement of a biliary endoprosthesis. | Duodenal perforation may occur at the time of insertion of a biliary endoprosthesis or following endoscopic manipulation of such a stent. The possibility of perforation as a late sequela of stent migration, after percutaneous placement of an endoprosthesis, however, has not been emphasized. In the authors' experience w... | ['Adult', 'Aged', 'Bile Ducts', 'Duodenum', 'Female', 'Foreign-Body Migration', 'Humans', 'Intestinal Perforation', 'Male', 'Middle Aged', 'Prostheses and Implants', 'Time Factors'] | 3,282,263 | [['M01.060.116'], ['M01.060.116.100'], ['A03.159.183'], ['A03.556.124.684.124', 'A03.556.875.249'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['M01.060.116.630'], ['E07.695'], ['G01.910.857']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Laparoscopic cholecystectomy in patients admitted with acute biliary symptoms. | Laparoscopic cholecystectomy has become the standard of care for the elective management of cholelithiasis. Little information exists, however, regarding the appropriateness of this procedure in the setting of acute symptomatology. We retrospectively reviewed our experience with 516 laparoscopic cholecystectomies perfo... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Cholangiography', 'Cholecystectomy, Laparoscopic', 'Cholelithiasis', 'Emergencies', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis', 'Retrospective Studies', 'Safety'] | 8,368,442 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.700.715.200', 'E01.370.372.200'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['C06.130.409'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A method for routine approach to laryngeal and hypopharyngeal surgical specimens by whole organ sections in the horizontal plane. | A procedure of pathological analysis of laryngopharyngeal specimens by whole organ sections in the horizontal plane was developed and evaluated. The use of a fast decalcifying and fixative solution allowed both an easier sectioning of the whole organ and thin (5-6 microns) histological whole organ sections of laryngo p... | ['Histocytochemistry', 'Humans', 'Hypopharyngeal Neoplasms', 'Laryngeal Neoplasms', 'Neoplasm Staging', 'Pathology', 'Pharyngeal Neoplasms'] | 2,710,686 | [['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.485'], ['C04.588.443.665.481', 'C08.360.369'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnetic resonance imaging at 7T reveals common events in age-related sarcopenia and in the homeostatic response to muscle sterile injury. | Skeletal muscle remodeling in response to various noxae physiologically includes structural changes and inflammatory events. The possibility to study those phenomena in-vivo has been hampered by the lack of validated imaging tools. In our study, we have relied on multiparametric magnetic resonance imaging for quantitat... | ['Aging', 'Animals', 'Cardiotoxins', 'Cell Movement', 'Diffusion Tensor Imaging', 'Female', 'Homeostasis', 'Leukocytes', 'Mice', 'Muscle, Skeletal', 'Myofibrils', 'Regeneration', 'Sarcopenia'] | 23,555,016 | [['G07.345.124'], ['B01.050'], ['D27.888.569.142'], ['G04.198', 'G07.568.500.180'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['G07.410'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['A02.633.567', 'A10.690.552.500'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recalled Separation Anxiety in Childhood in Istmo Zapotec Men, Women, and Muxes. | The Istmo Zapotec are a pre-Columbian cultural group indigenous to the Istmo region of Oaxaca, Mexico. Istmo Zapotec recognize three genders: men, women, and muxes. Like Istmo Zapotec men, muxes are biological males. However, unlike Istmo Zapotec men, most muxes are exclusively androphilic (i.e., sexually attracted to ... | ['Adult', 'Anxiety, Separation', 'Female', 'Gender Identity', 'Homosexuality, Male', 'Humans', 'Male', 'Mental Recall', 'Retrospective Studies', 'Samoa', 'Sexual Behavior'] | 28,050,743 | [['M01.060.116'], ['F03.080.300', 'F03.625.047'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750',... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A postulated mechanism for heparin's potentiation of C1 inhibitor function. | Conflicting reports exist in the literature concerning the primary mechanism for heparin's inhibition of C1 hemolytic function. We provide evidence here that heparin's most effective inhibition is mediated through interaction with and potentiation of C1-INH. The molecular nature of the interaction between heparin and t... | ['Complement Activation', 'Complement C1 Inactivator Proteins', 'Complement C3', 'Complement C4', 'Complement Pathway, Classical', 'Hemolysis', 'Heparin', 'Humans', 'Immunoelectrophoresis', 'Immunoglobulin G'] | 7,099,168 | [['G12.274'], ['D12.644.861.140', 'D12.776.124.486.274.920.250', 'D12.776.872.140'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274.350'], ['G12.274.698'], ['C23.550.403', 'G12.122.545'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350.350',... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Memory complaints in chronic stroke patients are predicted by memory self-efficacy rather than memory capacity. | BACKGROUND: Memory self-efficacy (MSE) is the belief about one's mastery of memory functioning. In healthy elderly, memory complaints are related to MSE rather than to objectively measured memory capacity. MSE has scarcely been studied in patients that suffered a stroke. The aim of this study was twofold: (1) to examin... | ['Aged', 'Chronic Disease', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Memory', 'Memory Disorders', 'Middle Aged', 'Multivariate Analysis', 'Neuropsychological Tests', 'Predictive Value of Tests', 'Self Efficacy', 'Stroke', 'Verbal Learning'] | 21,487,221 | [['M01.060.116.100'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients. | BACKGROUND: Interindividual differences in the structure and expression of the dopamine receptor genes affect dopamine availability and may be the genetic basis for variation in vulnerability to tobacco smoking. In this study, prevalences of polymorphisms in the TaqIA allele (A1 and A2) and the TaqIB allele (B1 and B2)... | ['Aged', 'Alleles', 'Case-Control Studies', 'DNA Primers', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Receptors, Dopamine D2', 'Smoking', 'Smoking Cessation', 'Tobacco Use Disorder'] | 9,498,485 | [['M01.060.116.100'], ['G05.360.340.024.340.030'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Interrogating transcriptional regulatory sequences in Tol2-mediated Xenopus transgenics. | Identifying gene regulatory elements and their target genes in vertebrates remains a significant challenge. It is now recognized that transcriptional regulatory sequences are critical in orchestrating dynamic controls of tissue-specific gene expression during vertebrate development and in adult tissues, and that these ... | ['Animals', 'Animals, Genetically Modified', 'Chromatin Immunoprecipitation', 'Larva', 'Molecular Sequence Data', 'Muscle, Skeletal', 'Regulatory Sequences, Nucleic Acid', 'Xenopus laevis'] | 23,874,664 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['E05.393.170', 'E05.478.605.160'], ['B05.500.500', 'G07.345.500.550.500.500'], ['L01.453.245.667'], ['A02.633.567', 'A10.690.552.500'], ['G02.111.570.080.689', 'G05.360.080.689'], ['B01.050.150.900.090.180.610.500.562']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reverse superior labial artery flap in reconstruction of nose and medial cheek defects. | BACKGROUND: Angular artery, lateral nasal artery, and infraorbital artery pedicled nasolabial flaps have been used for reconstruction of lower nose and medial cheek defects. An alternative pedicle to raise a flap in the nasolabial area is the superior labial artery. Superior labial artery is a constant branch of the fa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Basal Cell', 'Carcinoma, Squamous Cell', 'Cheek', 'Ear Cartilage', 'Facial Neoplasms', 'Female', 'Humans', 'Lip', 'Male', 'Middle Aged', 'Nose', 'Nose Neoplasms', 'Reconstructive Surgical Procedures', 'Skin Neoplasms', 'Surgical Flaps', 'Treatment Outcome'] | 24,051,456 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A01.456.505.173', 'A14.194'], ['A02.165.257.250', 'A09.246.272.549'], ['C04.588.443.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.505.631.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytoplasmic p27 is a novel prognostic biomarker and oncogenic protein for nasopharyngeal carcinoma. | Cytoplasmic p27 plays an important role in regulating the cell cycle. Recent studies have revealed p27 protein translocation from the nucleus to the cytoplasm in many tumour cells. The aim of this study was to investigate the role and molecular mechanisms of cytoplasmic p27 in the progression of nasopharyngeal carcinom... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Cyclin-Dependent Kinase Inhibitor p27', 'Cytoplasm', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Prognosis'] | 31,884,829 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.360.225.600', 'D12.776.167.187.600', 'D12.776.476.225.600', 'D12.776.624.776.355.600'], ['A11.284.430.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.470.200.623', 'C04.588.44... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A bridge between neuroscience and oncology: prostate cancer genesis. A 'negative' consequence of learning? | Prostate cancer has become the most commonly diagnosed cancer in men over recent years. The initiating mechanism for tumorigenesis within the prostate remains an unknown. The observation, that the cancer incidence in patients with chronic neurological disabilities is significantly lower than in the normal population le... | ['Cell Transformation, Neoplastic', 'Central Nervous System', 'Humans', 'Male', 'Prostatic Neoplasms'] | 11,461,173 | [['C04.697.098.500', 'C23.550.727.098.500'], ['A08.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Loco-regional chemotherapy at the outpatient clinic for gastric cancer patients with home enteral nutrition]. | In over the 10 years from 2000-2010, 21 gastric cancer patients received loco-regional chemotherapy with home enteral nutrition (HEN) at an outpatient clinic because of insufficient oral intake. These loco-regional chemotherapy regimens consisted of 5 intra-aortic chemotherapies, 4 hepato-arterial infusions and 12 intr... | ['Aged', 'Ambulatory Care Facilities', 'Antineoplastic Agents', 'Enteral Nutrition', 'Female', 'Home Care Services', 'Humans', 'Male', 'Neoplasm Staging', 'Stomach Neoplasms'] | 22,202,384 | [['M01.060.116.100'], ['N02.278.035'], ['D27.505.954.248'], ['E02.421.360', 'E02.642.500.360'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
White mold on cultivated morels caused by Paecilomyces penicillatus. | Morchella (morel) includes prized edible and medical mushrooms in the world. Since 2012, commercial cultivation of morels in the field has developed rapidly in China. However, coupled with the rapid expansion of morel cultivation, diseases have been become serious threats to morel production. White mold is one of the m... | ['Agaricales', 'China', 'DNA, Fungal', 'DNA, Ribosomal Spacer', 'Fruiting Bodies, Fungal', 'Paecilomyces', 'Phylogeny', 'Sequence Analysis, DNA'] | 28,199,636 | [['B01.300.179.100'], ['Z01.252.474.164'], ['D13.444.308.300'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['A19.374'], ['B01.300.381.640'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700']] | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Solar keratoma: An atypical case. | This case report shows that keratomas can occur in both hind feet of equine patients and should be considered as a diagnosis for long-standing, intermittent lameness localised to the hooves. A Thoroughbred racehorse presented with long-standing abscessation of the right hind hoof. Owing to the long-standing nature, the... | ['Animals', 'Debridement', 'Diagnosis, Differential', 'Hindlimb', 'Hoof and Claw', 'Horse Diseases', 'Horses', 'Keratosis', 'Lameness, Animal', 'Male', 'Physical Endurance'] | 26,824,342 | [['B01.050'], ['E04.176'], ['E01.171'], ['A13.473'], ['A13.491'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C17.800.428'], ['C22.510'], ['G11.427.680', 'I03.450.642.845.054.600']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Burden of neurological conditions in Canada. | Neurological conditions are among the leading causes of disability in the Canadian population and are associated with a large public health burden. An increase in life expectancy and a declining birth rate has resulted in an aging Canadian population, and the proportion of age-adjusted mortality due to non-communicable... | ['Canada', 'Female', 'Humans', 'Male', 'Nervous System Diseases', 'Public Health', 'World Health Organization'] | 27,153,747 | [['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['N03.540.514.718.800']] | ['Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Exemplary professional practice through nurse peer review. | The development and execution of a nurse peer review program to evaluate nursing practice associated with significant adverse events has resulted in systemic changes. Descriptive analyses were conducted for 23 peer-reviewed cases involving 41 RNs and 2 advanced practice nurses from 14 specialties over a 4-year period. ... | ['Boston', 'Child', 'Health Plan Implementation', 'Hospitals, Pediatric', 'Humans', 'Nursing Care', 'Organizational Innovation', 'Peer Review, Health Care', 'Professional Staff Committees'] | 21,419,972 | [['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['M01.060.406'], ['N03.349.300'], ['N02.278.421.556.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.611', 'N02.421.533'], ['N04.452.610'], ['F01.829.316.549.690', 'I01.880.604.640.690', 'N03.706.700.690', 'N04.761.616', 'N05.715.680'], ['N04.452.758.788... | ['Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Incidence of prominent corneal nerves in multiple endocrine neoplasia type 2A. | We studied the increased visibility of corneal nerves inside an 8-mm diameter central corneal area in 14 patients with multiple endocrine neoplasia type 2A, one patient with multiple endocrine neoplasia type 2B, five patients with nonhereditary medullary thyroid carcinoma, ten patients with anterior keratoconus, and te... | ['Adult', 'Aged', 'Carcinoma', 'Cornea', 'Female', 'Humans', 'Incidence', 'Keratoconus', 'Male', 'Middle Aged', 'Multiple Endocrine Neoplasia', 'Thyroid Neoplasms'] | 1,672,053 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200'], ['A09.371.060.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C11.204.627'], ['M01.060.116.630'], ['C04.588.322.400', 'C04.651.600', 'C0... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rationale for immediate reconstruction of the breast following modified radical mastectomy. | In 62 patients in whom modified radical mastectomy was accompanied by immediate breast reconstruction, the operative and pathologic findings are compared to the clinical results. Immediate reconstruction following modified radical mastectomy appears to offer several advantages over delayed reconstruction. The data indi... | ['Adult', 'Breast', 'Breast Neoplasms', 'Cost-Benefit Analysis', 'Female', 'Humans', 'Mastectomy', 'Middle Aged', 'Nipples', 'Postoperative Care', 'Prostheses and Implants', 'Surgery, Plastic', 'Time Factors'] | 6,803,649 | [['M01.060.116'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['N03.219.151.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466'], ['M01.060.116.630'], ['A01.236.500'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E07.695'], ['H02.403.810.788'], ['G01.910.857']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice. | Tumor necrosis factor-á (TNF-á) is a key factor for the pathogenesis of inflammatory bowel diseases (IBD), whose function is known to be mediated by TNF receptor 1 (TNFR1) or 2. However, the precise role of the two receptors in IBD remains poorly understood. Herein, acute colitis was induced by dextran sulfate sodium (... | ['Animals', 'Apoptosis', 'Cells, Cultured', 'Dextran Sulfate', 'Inflammatory Bowel Diseases', 'Intestinal Mucosa', 'Mice', 'Mice, Inbred BALB C', 'Mice, Knockout', 'Receptors, Tumor Necrosis Factor, Type I', 'Receptors, Tumor Necrosis Factor, Type II', 'Survival Analysis', 'Tumor Necrosis Factor-alpha', 'Weight Loss'] | 23,285,227 | [['B01.050'], ['G04.146.954.035'], ['A11.251'], ['D09.698.365.272.300'], ['C06.405.205.731', 'C06.405.469.432'], ['A03.556.124.369', 'A10.615.550.444'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.136.500.500', 'B01.050.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Carotenoid analysis of sweetpotato Ipomoea batatas and functional identification of its lycopene â- and å-cyclase genes. | Sweetpotato Ipomoea batatas is known as a hexaploid species. Here, we analyzed carotenoids contained in the leaves and tubers of sweetpotato cultivars 'White Star' (WS) and W71. These cultivars were found to contain several carotenoids unique to sweetpotato tubers such as â-carotene-5,6,5',8'-diepoxide and â-carotene-5... | ['Biosynthetic Pathways', 'Carotenoids', 'Chromatography, High Pressure Liquid', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Intramolecular Lyases', 'Ipomoea batatas', 'Molecular Structure', 'Phylogeny', 'Plant Leaves', 'Plant Proteins', 'Reverse Transcriptase Polymerase Chain React... | 27,564,699 | [['G02.111.098', 'G03.493.100'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['E05.196.181.400.300'], ['G05.308.320'], ['G05.308.375'], ['D08.811.399.430'], ['B01.650.940.800.575.912.250.238.500.500'], ['G02.111.570', 'G02.466'], ['G05.697', 'G16.075.605', 'L01.100.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Secondary prevention of acute myocardial infarction with beta-blocking agents and calcium antagonists. | The discovery that beta blockers possess clinically useful hypotensive, antianginal and antiarrhythmic properties has attracted the interest of clinicians, researchers and the pharmaceutical community alike. In addition, minor differences in a variety of ancillary properties have led to speculation that specific classe... | ['Adrenergic beta-Antagonists', 'Algorithms', 'Calcium Channel Blockers', 'Humans', 'Meta-Analysis as Topic', 'Myocardial Infarction', 'Time Factors'] | 1,977,303 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['G17.035', 'L01.224.050'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500', 'E05.581.500.501', 'N05.715.360.325.515', 'N06.850.520.445.500'], ['C14.280.647.500', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Caregiver alcohol use and mental health among children orphaned by HIV/AIDS in South Africa. | Research in the developed world suggests that parental alcohol use negatively impacts child mental health. However, little research has examined these relations among children in the developing world and no studies to date have done so in the context of AIDS-orphanhood. Therefore, the present study tested the interacti... | ['Acquired Immunodeficiency Syndrome', 'Alcohol Drinking', 'Caregivers', 'Child', 'Child, Orphaned', 'Female', 'Humans', 'Male', 'Mental Disorders', 'South Africa'] | 27,569,763 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['F01.145.317.269'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.108'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cadmium-113 nuclear magnetic resonance investigation of metal binding sites in concanavalin A. | Cadmium-113 nuclear magnetic resonance studies are presented on the 113Cd-substituted protein concanavalin A (Con A). This protein has two different conformations, locked and unlocked, as described previously by Brown et al. [Brown, R. D., III, Brewer, C. F., & Koenig, S. H. (1977) Biochemistry 16, 3883]. The unlocked ... | ['Binding Sites', 'Cadmium', 'Calcium', 'Chemical Phenomena', 'Chemistry, Physical', 'Concanavalin A', 'Isotopes', 'Lead', 'Magnetic Resonance Spectroscopy', 'Zinc'] | 7,459,324 | [['G02.111.570.120'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02'], ['H01.181.529'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D01.496'], ['D01.268.556.435', 'D01.552.544.435'], ['E05.196.867.519'], ['D01.268.556.940', 'D01.268.956.906... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Chiral HPLC determination and stereoselective pharmacokinetics of tetrahydroberberine enantiomers in rats. | Tetrahydroberberine (THB), a racemic mixture of (+)- and (-)-enantiomer, is a biologically active ingredient isolated from a traditional Chinese herb Rhizoma corydalis (yanhusuo). A chiral high performance liquid chromatography method has been developed for the determination of THB enantiomers in rat plasma. The enanti... | ['Animals', 'Berberine', 'Chromatography, High Pressure Liquid', 'Drugs, Chinese Herbal', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Reproducibility of Results', 'Stereoisomerism', 'Substrate Specificity'] | 22,271,601 | [['B01.050'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['E05.196.181.400.300'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G02.607.445.682'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolation, cultivation and identification of Borrelia burgdorferi genospecies from Ixodes ricinus ticks from the city of Brno, Czech Republic. | A total of 305 ticks (21 larvae, 243 nymphs, 19 females and 22 males) were collected by flagging of vegetation in suburban woods of Pisarky Park (city of Brno) from July to October 2002. The midgut of each tick was dissected out and transferred individually into BSK-H medium. After cultivation, all specimens were exami... | ['Animals', 'Arachnid Vectors', 'Borrelia burgdorferi Group', 'Czech Republic', 'DNA, Bacterial', 'Disease Reservoirs', 'Environmental Monitoring', 'Epidemiological Monitoring', 'Female', 'Humans', 'Ixodes', 'Larva', 'Lyme Disease', 'Male', 'Nymph', 'Phylogeny', 'Polymerase Chain Reaction', 'Polymorphism, Restriction F... | 17,655,181 | [['B01.050'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['B03.440.425.410.711.193.150', 'B03.851.595.193.150'], ['Z01.542.248.395'], ['D13.444.308.212'], ['N06.850.520.203.250'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.375', 'N06.850.520.460'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
[Preventing effect of TGF-beta1 antibody compounded with fibrin glue on postoperative adhesions of flexor tendon]. | OBJECTIVE: To explore the preventing effects of TGF-beta1 antibody (TGF-beta1Ab) compounded with fibrin glue (FG) on postoperative adhesions of flexor tendon.METHODS: Seventy-two Leghorn chickens were randomly divided into 4 groups (groups A, B, C and D), 18 chickens for each group, and the long flexor tendons of the 3... | ['Animals', 'Antibodies', 'Biomechanical Phenomena', 'Chickens', 'Fibrin Tissue Adhesive', 'Male', 'Random Allocation', 'Suture Techniques', 'Tendon Injuries', 'Tissue Adhesions', 'Toes', 'Transforming Growth Factor beta1', 'Treatment Outcome', 'Weight-Bearing', 'Wound Healing'] | 18,396,720 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D12.776.124.270.305'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E04.987.775'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of surface properties of picornaviruses: strategies for hiding the receptor site from immune surveillance. | The surface topology and sequence conservation of different picornaviruses have been compared using molecular graphics and statistical analyses. The comparisons suggest that the canyons, surface depressions encircling the fivefold axes, are the sites of receptor attachment of enteroviruses as well as human rhinovirus (... | ['Picornaviridae', 'Receptors, Virus', 'Surface Properties'] | 8,337,843 | [['B04.820.578.750'], ['D12.776.543.750.830'], ['G02.860']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The efficacy of pregabalin and benzodiazepines in generalized anxiety disorder presenting with high levels of insomnia. | The objective of this study was to assess the impact of high levels of insomnia on response to pregabalin (PGB) in patients with generalized anxiety disorder (GAD). Pooled data were analyzed from six double-blind, placebo-controlled, 4- to 6-week trials of outpatients who met the Diagnostic and Statistical Manual of Me... | ['Adult', 'Anxiety Disorders', 'Benzodiazepines', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Placebos', 'Pregabalin', 'Sleep Initiation and Maintenance Disorders', 'gamma-Aminobutyric Acid'] | 19,542,983 | [['M01.060.116'], ['F03.080'], ['D03.633.100.079.080'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.660', 'E02.785'], ['D02.241.081.114.500.350.500', 'D12.125.190.350.450'], ['C10.886.425.800.800', 'F03.870.400.800.800'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Radiation dose for body CT protocols: variability of scanners at one institution. | OBJECTIVE: The objective of our study was to determine, using an anthropomorphic phantom, whether patients are subject to variable radiation doses based on scanner assignment for common body CT studies.MATERIALS AND METHODS: Twenty metal oxide semiconductor field effect transistor dosimeters were placed in a medium-siz... | ['Adult', 'Body Burden', 'Equipment Design', 'Equipment Failure Analysis', 'Humans', 'Male', 'Phantoms, Imaging', 'Relative Biological Effectiveness', 'Tomography, X-Ray Computed', 'Whole-Body Counting'] | 19,770,340 | [['M01.060.116'], ['E05.799.638.231', 'N06.850.460.200'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['N06.850.810.250.275'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['E05.79... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of chlorine on cultivability of Shiga toxin producing Escherichia coli (STEC) and â-lactamase genes carrying E. coli and Pseudomonas aeruginosa. | The worldwide spread of toxin-producing and multi-drug resistant bacteria in water, food and the environment is considered a major threat to human health. Drinking water quality is controlled by inspection of fecal indicators presence whereby viable contaminants will be efficiently reduced by chlorination which is a co... | ['Animals', 'Chemical Warfare Agents', 'Chlorine', 'Drug Resistance, Multiple, Bacterial', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Humans', 'Microbial Viability', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Shiga-Toxigenic Escherichia coli', 'Water Microbiology', 'beta-Lactamases'] | 30,262,431 | [['B01.050'], ['D27.720.777.300', 'D27.888.569.612.150', 'J01.637.870.900.200'], ['D01.268.380.150', 'D01.362.225'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['C01.150.252.400.310.330'], ['D12.776.097.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Saccharomyces cerevisiae Hop1 protein zinc finger motif binds to the Holliday junction and distorts the DNA structure: implications for holliday junction migration. | Saccharomyces cerevisiae HOP1, which encodes a component of synaptonemal complex, plays an important role in crossing over between homologues. Hop1p contains a zinc finger motif, and substitution of a conserved Cys371 by Ser rendered the hop1 mutant allele defective in sporulation and meiosis. However, the molecular me... | ['Adenosine Triphosphatases', 'Amino Acid Sequence', 'Base Sequence', 'DNA Helicases', 'DNA, Cruciform', 'DNA, Fungal', 'DNA-Binding Proteins', 'Dimerization', 'Models, Molecular', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Protein Binding', 'Protein Folding', 'RecQ Helicases', 'Saccharomyces cerevisiae',... | 17,935,355 | [['D08.811.277.040.025'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D13.444.308.295', 'G02.111.570.820.486.325', 'G05.360.580.325'], ['D13.444.308.300'], ['D12.776.260'], ['G02.206', 'G03.230'], ['E05.599.595'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pinnatifidenyne-Derived Ethynyl Oxirane Acetogenins from Laurencia viridis. | Red algae of Laurencia continue to provide wide structural diversity and complexity of halogenated C15 acetogenin medium-ring ethers. Here, we described the isolation of three new C15 acetogenins (3-5), and one truncated derivative (6) from Laurencia viridis collected on the Canary Islands. These compounds are interest... | ['Acetogenins', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'Ethers, Cyclic', 'Ethylene Oxide', 'Humans', 'Laurencia', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Conformation', 'Molecular Structure'] | 29,286,293 | [['D02.033.415.054', 'D02.455.326.146.049', 'D02.540.576.250', 'D03.383.312.200', 'D04.345.674.250', 'D10.289.054'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D02.355.291', 'D04.345.241'], ['D02.355.291.411.417'], ['B01.0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation in laryngeal carcinoma. | Over-expression of DNA methyltransferase 1 (DNMT1) correlates with hypermethylation of tumor suppressor genes (TSGs) in tobacco-induced cancers. The tobacco component nitrosamine 4-(methylnitro-samino)-1-(3-pyridyl)-1-butanone (NNK) increases protein levels of the DNMT1 in human lung cancer. However, the role of DNMT1 ... | ['Adult', 'Aged', 'Blotting, Western', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Female', 'Humans', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', 'Nitrosamines', 'Prognosis', 'RNA, Messenger', 'Repressor Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Risk Factors', 'Smoking'] | 22,317,856 | [['M01.060.116'], ['M01.060.116.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[What will our future look like? Answer, if you can! Perspectives from nursing students about their professional future]. | This is a qualitative study aimed at: identifying significant factors in nurse education; presenting a nurse profile as perceived by an undergraduate student; getting to know the perspectives nursing students have for their future professional lives. The interviewees were twelve students in nursing undergraduate progra... | ['Brazil', 'Forecasting', 'Nursing', 'Students, Nursing'] | 14,699,775 | [['Z01.107.757.176'], ['I01.320'], ['H02.478', 'N04.452.758.377'], ['M01.848.769.685']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Prevention of sexually transmitted diseases among visually impaired people: educational text validation. | OBJECTIVE: to validate an educational text in the context of Sexually Transmitted Diseases (STD) for visually impaired persons, making it accessible to this population.METHOD: a validation study, in a virtual environment. Data collection occurred from May to September 2012 by emailing the subjects, and was composed by ... | ['Health Education', 'Humans', 'Sexually Transmitted Diseases', 'Virtual Reality', 'Visually Impaired Persons'] | 27,556,880 | [['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.221.812', 'C01.778', 'C12.294.668', 'C13.351.500.711', 'C23.550.291.531.937'], ['L01.224.160.875', 'L01.296.555'], ['M01.150.850']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
The cost and analysis of nonuse of cochlear implants. | OBJECTIVE: Analysis of the cost implications and reasons for nonuse of cochlear implants in an established cochlear implant unit.STUDY DESIGN: Clinical data were analyzed retrospectively to construct a table of cochlear implant use over time to identify nonuse and to suggest the reasons for this.SETTING: Yorkshire Coch... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cochlear Implants', 'Costs and Cost Analysis', 'Female', 'Humans', 'Life Tables', 'Male', 'Retrospective Studies', 'Treatment Refusal'] | 18,046,260 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['N03.219.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.475', 'E05.318.740.100.500', 'N01.224.935.530', 'N06.850.505.400.975.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Left ventricular rotational dynamics in Beta thalassemia major: a speckle-tracking echocardiographic study. | BACKGROUND: Iron-mediated cardiomyopathy is the leading cause of death in patients with thalassemia major (TM). The identification of subclinical cardiac involvement in the early phases of the disease is important to optimize therapeutic strategies. The aim of this study was to identify early markers of cardiac dysfunc... | ['Adult', 'Algorithms', 'Echocardiography', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Iron Overload', 'Male', 'Reproducibility of Results', 'Rotation', 'Sensitivity and Specificity', 'Ventricular Dysfunction, Left', 'beta-Thalassemia'] | 22,898,242 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['C18.452.565.500'], ['E05.318.370.725', 'E... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Assessing long-term effects of multiple, potentially confounded drivers in ecosystems from species traits. | Although species traits have the potential to disentangle long-term effects of multiple, potentially confounded drivers in ecosystems, this issue has received very little attention in the literature. We aimed at filling this gap by assessing the relative effects of hydroclimatic and water quality factors on the trait c... | ['Animals', 'Climate Change', 'Ecosystem', 'France', 'Invertebrates', 'Population Dynamics', 'Rivers', 'Time Factors'] | 27,873,443 | [['B01.050'], ['G16.500.175.374'], ['G16.500.275.157', 'N06.230.124'], ['Z01.542.286'], ['B01.050.500'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
HISTOPATHOLOGIC CHARACTERISTICS OF THYROID GLAND NEOPLASMS IN THOMSON'S GAZELLES ( EUDORCUS THOMSONII). | Published reports of neoplasms in Thomson's gazelles ( Eudorcas thomsonii) are very rare, but thyroid tumors were the most common neoplasm of this species, accounting for 12% of reported pathologies in a 1998-2012 retrospective study of cases submitted for histologic review of grossly enlarged thyroid glands. This repo... | ['Animals', 'Animals, Zoo', 'Antelopes', 'Retrospective Studies', 'Thyroid Gland', 'Thyroid Neoplasms'] | 29,517,438 | [['B01.050'], ['B01.050.050.448'], ['B01.050.150.900.649.313.500.380.100'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['A06.300.900'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Treatment of hepatocellular carcinoma in a rat model using electrochemotherapy. | The effectiveness of antineoplastic agents has been augmented by applying pulsed electric fields directly to tumours after the administration of the drug. This treatment, known as electrochemotherapy (ECT), has been successful for cutaneous malignancies in animal models and in recent clinical trials. This study was aim... | ['Animals', 'Antibiotics, Antineoplastic', 'Bleomycin', 'Carcinoma, Hepatocellular', 'Dose-Response Relationship, Drug', 'Electroporation', 'Liver Neoplasms', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Tumor Cells, Cultured'] | 11,239,766 | [['B01.050'], ['D27.505.954.248.106'], ['D09.400.420.110', 'D12.644.233.110'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['B01.050... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Blood: what's new and over the horizon. | The ever-increasing demand for blood and blood products has resulted in extensive and accelerated research in the area of blood replacement. Improvements have been made in techniques for prolonging the shelf life of blood. Autotransfusion, a concept originating the early 1800s, has been refined and advanced to a point ... | ['Blood Donors', 'Blood Preservation', 'Blood Substitutes', 'Blood Transfusion, Autologous', 'Cadaver', 'Fluorocarbons', 'Humans'] | 7,300,702 | [['M01.898.313'], ['E02.792.833.230', 'E05.760.833.230'], ['D27.505.954.502.140', 'J01.637.087.249'], ['E02.095.135.164'], ['C23.550.260.224'], ['D02.455.526.510.435'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Recovery from vecuronium is delayed in patients with hypercholesterolemia. | PURPOSE: To examine the effects of hypercholesterolemia with respect to onset time and recovery from vecuronium-induced neuromuscular block.METHODS: A randomized controlled trial was undertaken in 20 adult patients with hypercholesterolemia (hypercholesterolemia group) and 20 healthy patients with normal serum choleste... | ['Aged', 'Anesthesia, General', 'Female', 'Humans', 'Hypercholesterolemia', 'Male', 'Middle Aged', 'Motor Neurons', 'Muscle, Skeletal', 'Nerve Fibers', 'Neuromuscular Blockade', 'Neuromuscular Nondepolarizing Agents', 'Preanesthetic Medication', 'Vecuronium Bromide'] | 16,738,289 | [['M01.060.116.100'], ['E03.155.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['M01.060.116.630'], ['A08.675.655.500', 'A11.671.655.500'], ['A02.633.567', 'A10.690.552.500'], ['A08.675.542', 'A11.671.501'], ['E03.706', 'E05.635'], ['D27.505.696.663.700.710.575'], ['E03.806', 'E04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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