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[Proposal for a program in the early diagnosis of breast cancer]. | Systematic examination of the breasts of women admitted to a medical ward for apparently non-breast-related pathologies revealed 22 cases of isolated nodules (2.06%) of which 9 (40.9%) were carcinomatous. It is pointed out that while mass screenings are impossibly expensive careful periodic clinical examination by the ... | ['Adult', 'Aged', 'Biopsy', 'Biopsy, Needle', 'Breast Neoplasms', 'Female', 'Humans', 'Mammography', 'Middle Aged', 'Palpation', 'Time Factors'] | 4,069,425 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
VDT work duration and musculoskeletal discomfort. | Musculoskeletal discomfort, work position, and job stress factors were compared in government office workers grouped according to whether they used video display terminals more or less than 4 hours per day. The results of this study suggest that limits on VDT use to less than 4 hours per day do not necessarily protect ... | ['Back Pain', 'Computer Systems', 'Humans', 'Occupational Diseases', 'Stress, Psychological', 'Surveys and Questionnaires', 'Work', 'Work Schedule Tolerance'] | 2,136,998 | [['C23.888.592.612.107'], ['L01.224.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C24'], ['F01.145.126.990', 'F02.830.900'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['I03.946'], ['I03.946.225.375', 'N04.452.677.650.375']] | ['Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Dephosphorylation of the insulin receptor partially restores the decreased autophosphorylation in streptozotocin induced diabetic rats. | The insulin resistance seen in diabetes mellitus has been attributed partly to impaired autophosphorylation of the insulin receptor. It has been suggested that the phosphorylation of serine and/or threonine residues of the insulin receptor may reduce tyrosine autophosphorylation in streptozotocin-induced diabetic rats ... | ['Alkaline Phosphatase', 'Animals', 'Diabetes Mellitus, Experimental', 'Insulin', 'Liver', 'Male', 'Phosphorylation', 'Protein Kinases', 'Rats', 'Rats, Inbred Strains', 'Receptor, Insulin', 'Reference Values'] | 1,816,977 | [['D08.811.277.352.650.035'], ['B01.050'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A03.620'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D08.811.913.696.620.682'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.76... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and pharmacological activity of 6-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethen-1-yl]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids. | 6-[(E)-2-(2,6,6-Trimethyl-1-cyclohexen-1-yl)ethen-1-yl]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids (4 and 8) have been synthesized and show significant activity in reversing the keratinization process in hamster tracheal organ culture and in inhibiting the induction of orni... | ['Animals', 'Biological Assay', 'Cricetinae', 'Enzyme Induction', 'Indicators and Reagents', 'Keratins', 'Mice', 'Naphthalenes', 'Organ Culture Techniques', 'Ornithine Decarboxylase', 'Skin', 'Structure-Activity Relationship', 'Tetradecanoylphorbol Acetate', 'Trachea'] | 6,195,339 | [['B01.050'], ['E05.091'], ['B01.050.150.900.649.313.992.635.075.250'], ['G05.308.320.200'], ['D27.720.470.410'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.455.426.559.847.638', 'D04.615.638'], ['E05.481.500.484'], ['D08.811.520.224.125.425'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A unique case of late complication of rectum mesh erosion after laparoscopic sacrocolpopexy. | Sacrocolpopexy, a surgical technique with a low morbidity rate, is a valid procedure for repairing vaginal vault prolapse. To our knowledge, only 1 case of rectum erosion after open sacrocolpopexy has been reported in the literature, and there is no record of any such incident after laparoscopic sacrocolpopexy. We repo... | ['Colonoscopy', 'Defecation', 'Female', 'Foreign-Body Migration', 'Gastrointestinal Hemorrhage', 'Gynecologic Surgical Procedures', 'Humans', 'Laparoscopy', 'Middle Aged', 'Rectal Diseases', 'Rectum', 'Reoperation', 'Surgical Mesh', 'Time Factors', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Uterine Prolapse'] | 24,334,820 | [['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['G10.261.165'], ['C26.392.500'], ['C06.405.227', 'C23.550.414.788'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['C06.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Positron emission tomography/computed tomography for lung cancer staging]. | BACKGROUND: PET/CT (Positron Emission Tomography/Computed Tomography) is widely used in nodal and metastatic staging of lung cancer patients.AIM: To analyze PET/CT detection of metastatic disease in patients with lung cancer.MATERIAL AND METHODS: We reviewed retrospectively F18Fluorodeoxyglucose PET/CT scans performed ... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Adenosquamous', 'Carcinoma, Squamous Cell', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Neoplasm Staging', 'Positron-Emission Tomography', 'Predictive Value of T... | 25,860,265 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.435.250', 'C04.557.470.200.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Genetic analysis of a pedigree affected with tuberous sclerosis complex caused by a novel mutation of TSC1]. | OBJECTIVE: To analyze the clinical phenotype of a Chinese pedigree affected with Tuberous sclerosis complex (TSC) and explore pathogenic mutations of TSC1 and TSC2 gene.METHODS: Unique clinical phenotypes?the results of imaging, examination of the proband and special family history, collectively, made the constellation... | ['DNA Mutational Analysis', 'Humans', 'Mutation', 'Pedigree', 'Tuberous Sclerosis', 'Tuberous Sclerosis Complex 1 Protein', 'Tuberous Sclerosis Complex 2 Protein'] | 31,598,936 | [['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['E05.393.673'], ['C04.445.810', 'C04.651.800', 'C04.700.700', 'C10.500.507.400.750', 'C10.562.850', 'C10.574.500.865', 'C16.131.666.507.400.750', 'C16.320.400.880', 'C16.320.700.700'], ['D12.644.360.925', 'D12.776.476.932', 'D1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LC-MS/MS analysis of uncommon paracetamol metabolites derived through in vitro polymerization and nitration reactions in liquid nitrogen. | Paracetamol (acetaminophen, APAP) is a commonly used analgesic drug. Known paracetamol metabolites include the glucuronide, sulfate and mercapturate. N-Acetyl-benzoquinonimine (NAPQI) is considered the toxic intermediate metabolite of paracetamol. In vitro and in vivo studies indicate that paracetamol is also metaboliz... | ['Acetaminophen', 'Animals', 'Chromatography, Liquid', 'Humans', 'Mice', 'Nitric Oxide', 'Nitrogen', 'Polymerization', 'Tandem Mass Spectrometry'] | 24,365,200 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['B01.050'], ['E05.196.181.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D01.268.604', 'D01.362.625'], ['G02.750'], ['E05.196.566.88... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five year cataract surgical rate in Iran. | PURPOSE: To determine the number of cataract surgeries per million population per year or the cataract surgical rate (CSR) in Iran for every year from 2000 to 2005 as part of the objectives of the Vision 2020 initiative by the World Health Organization (WHO) to eliminate cataract blindness.METHODS: This study is part o... | ['Cataract Extraction', 'Confidence Intervals', 'Cross-Sectional Studies', 'Humans', 'Iran', 'Middle Aged', 'Retrospective Studies', 'Statistics as Topic'] | 19,521,267 | [['E04.540.825.249'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Depression and Anxiety Are Risk Factors for Postoperative Pain-Related Symptoms and Complications in Patients Undergoing Primary Total Knee Arthroplasty in the United States. | BACKGROUND: The study was designed to analyze the underlying relationship between psychiatric comorbidities and postoperative outcomes in patients undergoing primary total knee arthroplasty (TKA).METHODS: We used the National Inpatient Sample data from 2002 to 2014. On the basis of the International Classification of D... | ['Adult', 'Aged', 'Anxiety', 'Arthroplasty, Replacement, Knee', 'Comorbidity', 'Depression', 'Female', 'Hospital Costs', 'Hospitalization', 'Humans', 'Inpatients', 'Male', 'Middle Aged', 'Odds Ratio', 'Pain Management', 'Pain, Postoperative', 'Prevalence', 'Quality of Life', 'Risk Factors', 'United States'] | 31,229,373 | [['M01.060.116'], ['M01.060.116.100'], ['F01.470.132'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cord blood platelet gel treatment of dystrophic recessive epidermolysis bullosa. | Epidermolysis bullosa (EB) is comprised of a group of hereditary mechanobullous disorders that are characterised by extremely fragile skin and mucous membranes. This results in blister formation and non-healing wounds. This case report describes the results of an innovative treatment of two large skin lesions in a newb... | ['Anemia', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Blood Platelets', 'Epidermolysis Bullosa Dystrophica', 'Erythropoietin', 'Female', 'Fetal Blood', 'Gels', 'Hemorrhage', 'Humans', 'Infant, Newborn', 'Superinfection'] | 25,572,600 | [['C15.378.071'], ['D27.505.954.122.085'], ['C01.150.252'], ['A11.118.188', 'A15.145.229.188'], ['C16.131.831.493.160', 'C16.320.850.275.160', 'C17.300.200.367', 'C17.800.804.493.160', 'C17.800.827.275.160', 'C17.800.865.410.160'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of a new standardized ramp protocol: the BSU/Bruce Ramp protocol. | BACKGROUND: Because of recent technological advances, exercise testing laboratories now have the ability to use ramp protocols with treadmill exercise tests. Since the Bruce protocol is the most widely used treadmill protocol in clinical laboratories, a standardized ramp treadmill protocol was developed that correspond... | ['Adult', 'Evaluation Studies as Topic', 'Exercise', 'Exercise Test', 'Female', 'Humans', 'Male', 'Oxygen Consumption', 'Regression Analysis', 'Reproducibility of Results'] | 9,857,276 | [['M01.060.116'], ['E05.337', 'N05.715.360.335'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.370.725', 'E05.337.851', 'N05.71... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The SCH9 protein kinase mRNA contains a long 5' leader with a small open reading frame. | The SCH9 yeast gene, that was previously identified as a suppressor of cdc25 and ras1- ras2-ts temperature-sensitive mutants, encodes a putative protein kinase that positively regulates the progression of yeast cells through the G1 phase of the cell cycle. We have determined the structure of the SCH9 transcription unit... | ['Alleles', 'Amino Acid Sequence', 'Base Sequence', 'G1 Phase', 'Gene Expression Regulation, Fungal', 'Genes, Suppressor', 'Molecular Sequence Data', 'Mutation', 'Open Reading Frames', 'Protein Kinases', 'RNA, Fungal', 'RNA, Messenger', 'Saccharomyces cerevisiae', 'Transcription, Genetic'] | 8,442,384 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144.500.320'], ['G05.308.330'], ['G05.360.340.024.340.460'], ['L01.453.245.667'], ['G05.365.590'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['D08.811.913.696.620.682'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Can Rachman's indirect pathways be used to un-learn fear? A prospective paradigm to test whether children's fears can be reduced using positive information and modelling a non-anxious response. | This study investigated whether children's fears could be un-learned using Rachman's indirect pathways for learning fear. We hypothesised that positive information and modelling a non-anxious response are effective methods of un-learning fears acquired through verbal information. One hundred and seven children aged 6-8... | ['Age Factors', 'Anxiety', 'Child', 'Fear', 'Female', 'Humans', 'Learning', 'Male', 'Models, Psychological', 'Neuropsychological Tests', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Sex Factors', 'Surveys and Questionnaires', 'Treatment Outcome'] | 19,875,101 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.470.132'], ['M01.060.406'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['E05.599.695'], ['F04.711.513'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['F04.711.513.653'... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The measurement of immediate and persistent radiation-induced chromosome damage in rodent primary cells using premature chromosome condensation. | The chromosome damage observed in cultured peripheral blood lymphocytes at their metaphase is considered to be the most reliable basis for biological dosimetry. However, physical and biological factors such as irradiation conditions and chromosome repair could make difficult the interpretation of chromosome aberration ... | ['Animals', 'Cell Fusion', 'Cell Line', 'Chromosome Aberrations', 'Cricetinae', 'Cricetulus', 'Female', 'In Vitro Techniques', 'Lymphocytes', 'Male', 'Methods', 'Mice', 'Ovary', 'Rats', 'Rats, Inbred Strains'] | 4,040,898 | [['B01.050'], ['E05.242.307', 'G04.155'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E05.481'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['E05.581'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tissue factor expression, angiogenesis, and thrombosis in pancreatic cancer. | PURPOSE: Hemostatic activation is common in pancreatic cancer and may be linked to angiogenesis and venous thromboembolism. We investigated expression of tissue factor (TF), the prime initiator of coagulation, in noninvasive and invasive pancreatic neoplasia. We correlated TF expression with vascular endothelial growth... | ['Aged', 'Capillaries', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neovascularization, Pathologic', 'Pancreatic Neoplasms', 'Survival Analysis', 'Thromboplastin', 'Vascular Endothelial Growth Factor A', 'Venous Thrombosis'] | 17,504,985 | [['M01.060.116.100'], ['A07.015.461.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.589.500'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['D12.776.124.125.900', 'D23.119.9... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus. | A peptide toxin, ShK, that blocks voltage-dependent potassium channels was isolated from the whole body extract of the Caribbean sea anemone Stichodactyla helianthus. It competes with dendrotoxin I and alpha-dendrotoxin for binding to synaptosomal membranes of rat brain, facilities acetylcholine release at an avian neu... | ['Amino Acid Sequence', 'Amino Acids', 'Animals', 'Cnidarian Venoms', 'Molecular Sequence Data', 'Potassium Channel Blockers', 'Potassium Channels', 'Rats', 'Sea Anemones', 'Synaptosomes'] | 7,660,365 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['B01.050'], ['D20.888.230', 'D23.946.580.230', 'D23.946.833.230'], ['L01.453.245.667'], ['D27.505.519.562.500', 'D27.505.954.411.645'], ['D12.776.157.530.400.600', 'D12.776.543.550.450.750', 'D12.776.543.585.400.750'], ['B01.050.150.900.649.313.992.635.505.700'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reninlike enzymatic activity in the cerebral microvessels of the rat. | Extrarenal renin has been a subject of considerable interest. Chiefly, studies have focused on brain and vascular renin activity in large arteries. A method now exists for the isolation from the cerebrum of microvascular tissues consisting of arterioles, capillaries and venules. The present study has demonstrated renin... | ['Angiotensin I', 'Animals', 'Arteries', 'Arterioles', 'Brain', 'Capillaries', 'Hydrogen-Ion Concentration', 'Kidney', 'Male', 'Pepstatins', 'Rats', 'Renin', 'Sodium', 'Veins', 'Venules'] | 6,989,271 | [['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['B01.050'], ['A07.015.114'], ['A07.015.114.060', 'A07.015.461.080'], ['A08.186.211'], ['A07.015.461.165'], ['G02.300'], ['A05.810.453'], ['D12.644.456.724'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extracellular and transmembrane region of a podocalyxin-like protein 1 fragment identified from colon cancer cell lines. | Regulated intramembrane proteolysis of membrane proteins has been shown to play an important role in cell differentiation and in the pathogenesis of diseases. The aim of the present study was to identify novel peptides generated by intramembrane proteolysis. The peptides were identified in serum-free cultured (SFC) med... | ['Amino Acid Sequence', 'Animals', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Colonic Neoplasms', 'Culture Media, Serum-Free', 'Humans', 'Membrane Proteins', 'Mice', 'Mice, Inbred BALB C', 'Neoplasm Proteins', 'Peptide Mapping', 'Protein Structure, Tertiary', 'Sialoglycoproteins', 'Spectrometry, Mass, Matrix-Assisted La... | 17,719,804 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D27.720.470.305.255', 'E07.206.255'], ['B01.050.150.900.649.31... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An affinity-modulating site on neuronal monoamine transport proteins. | The dissociation rates of [3H]nisoxetine, [3H]GBR 12935 and [3H]citalopram from, respectively, the rat brain noradrenaline, dopamine and 5-HT transporters were found to be markedly affected by several drugs. Sertraline strongly attenuated the rate of dissociation of [3H]nisoxetine from the noradrenaline transporter, wh... | ['1-Naphthylamine', 'Animals', 'Binding Sites', 'Biogenic Monoamines', 'Cerebral Cortex', 'Citalopram', 'Corpus Striatum', 'Female', 'Fluoxetine', 'In Vitro Techniques', 'Kinetics', 'Neurons', 'Piperazines', 'Rats', 'Receptors, Neurotransmitter', 'Sertraline', 'Stereoisomerism'] | 9,140,140 | [['D02.092.705', 'D02.455.426.559.847.638.845', 'D04.615.638.845'], ['B01.050'], ['G02.111.570.120'], ['D02.092.211.215'], ['A08.186.211.200.885.287.500'], ['D02.092.831.170', 'D02.626.320', 'D03.633.100.127.187'], ['A08.186.211.200.885.287.249.487'], ['D02.092.831.280'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Action of the Na+ ionophore monensin on vascular smooth muscle of guinea-pig aorta. | The effects of the Na+ ionophore monensin on contractile responses were investigated in guinea-pig aorta in normal and high K+ solutions. In normal K+ (5.4 mM) solution, monensin (2 X 10(-5) M) produced a rapid increase in tension followed by slow relaxation. This contraction was markedly inhibited by phentolamine (10(... | ['Adenosine Triphosphate', 'Animals', 'Aorta, Thoracic', 'Furans', 'Glucose', 'Guinea Pigs', 'Hypoxia', 'In Vitro Techniques', 'Male', 'Monensin', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Norepinephrine', 'Ouabain', 'Phentolamine', 'Potassium', 'Prazosin', 'Sodium', 'Verapamil'] | 6,734,722 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A07.015.114.056.372'], ['D03.383.312'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.992.550'], ['C23.888.852.079'], ['E05.481'], ['D03.383.312.600'], ['G11.427.494'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of malnutrition and environment on the acquisition and extinction of avoidance behavior in rats. | Twelve newborn rats were fed by mothers maintained on a protein-deficient diet (12% casein, M) during lactation, and 12 rats fed by mothers maintained on a diet containing 25% casein were used as controls (C). After weaning, all animals were fed standard lab ration. Half of each group was housed individually (MI and CI... | ['Animals', 'Animals, Newborn', 'Avoidance Learning', 'Body Weight', 'Electroshock', 'Extinction, Psychological', 'Female', 'Humans', 'Lactation', 'Learning Disabilities', 'Male', 'Pregnancy', 'Protein Deficiency', 'Rats', 'Rats, Inbred Strains', 'Reaction Time'] | 4,041,048 | [['B01.050'], ['B01.050.050.282'], ['F02.463.425.097', 'F02.463.785.373.173'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.723.402.403', 'F04.669.224'], ['F02.463.425.770.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.523'... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gender differences in legal outcomes of filicide in Austria and Finland. | Female offenders of filicide have been found to receive more lenient legal handling than male offenders. We aimed to discover these possible gender differences in the legal outcome of filicide cases. This was a binational register-based study covering all filicide offenders in Austria and Finland 1995-2005. We examined... | ['Adult', 'Austria', 'Child, Preschool', 'Criminals', 'Fathers', 'Female', 'Finland', 'Homicide', 'Humans', 'Infant', 'Infanticide', 'Male', 'Mothers', 'Registries', 'Sex Factors'] | 29,858,928 | [['M01.060.116'], ['Z01.542.088'], ['M01.060.406.448'], ['M01.142'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['Z01.542.816.186'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['I01.198.240.470.572'], ['F01.829.263.500.320.20... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
ERK and p38 MAP kinase are required for rat renal development. | BACKGROUND: We previously demonstrated that extracellular signal-regulated protein kinase (ERK) and p38 mitogen-activated protein (MAP) kinase (p38) are strongly expressed in the embryonic kidney. In the present study, we investigated the role of ERK and p38 during kidney development.METHODS: Rat metanephroi were cultu... | ['Animals', 'Apoptosis', 'Embryonic and Fetal Development', 'Enzyme Inhibitors', 'Eosine Yellowish-(YS)', 'Gene Expression', 'Hematoxylin', 'Kidney', 'Kidney Glomerulus', 'Mitogen-Activated Protein Kinases', 'Organ Culture Techniques', 'Proliferating Cell Nuclear Antigen', 'Rats', 'Rats, Sprague-Dawley', 'Staining and ... | 11,918,731 | [['B01.050'], ['G04.146.954.035'], ['G07.345.500.325', 'G08.686.784.170'], ['D27.505.519.389'], ['D02.455.426.779.347.325', 'D03.633.300.953.275.325', 'D04.711.347.325'], ['G05.297'], ['D03.383.663.283.600', 'D03.633.100.150.600'], ['A05.810.453'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['D08.811.913.696.620.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe acanthamoeba keratitis after overnight orthokeratology. | PURPOSE: To document a clinical case of Acanthamoeba keratitis associated with orthokeratology overnight lens wear that resulted in severe, permanent vision loss.METHODS: Case report.RESULTS: At the age of 11 years, a boy received a spectacle correction for the following refractive error: -3.25 -0.50 x090 in the right ... | ['Acanthamoeba Keratitis', 'Cataract', 'Child', 'Circadian Rhythm', 'Contact Lens Solutions', 'Contact Lenses', 'Corneal Ulcer', 'Glaucoma, Angle-Closure', 'Humans', 'Hygiene', 'Male', 'Severity of Illness Index', 'Time Factors', 'Vision Disorders', 'Water'] | 17,502,745 | [['C01.610.300.125', 'C01.610.752.049.203', 'C11.204.564.112', 'C11.294.725.125'], ['C11.510.245'], ['M01.060.406'], ['G07.180.562.190'], ['D26.776.210', 'D27.505.954.122.425.150', 'D27.720.274.150'], ['E07.632.500.276'], ['C01.375.177', 'C11.204.564.225', 'C11.294.177'], ['C11.525.381.056'], ['B01.050.150.900.649.313.... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterizing the relationship between temperature and mortality in tropical and subtropical cities: a distributed lag non-linear model analysis in Hue, Viet Nam, 2009-2013. | BACKGROUND: The relationship between temperature and mortality has been found to be U-, V-, or J-shaped in developed temperate countries; however, in developing tropical/subtropical cities, it remains unclear.OBJECTIVES: Our goal was to investigate the relationship between temperature and mortality in Hue, a subtropica... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Child', 'Child, Preschool', 'Cities', 'Female', 'Global Health', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Mortality', 'Nonlinear Dynamics', 'Risk Factors', 'Sex Distribution', 'Temperature', 'Vietnam', 'Weather', 'Young Adult'] | 26,781,954 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Peripheral macrophage depletion reduces central nervous system parasitism and damage in Trypanosoma cruzi-infected suckling rats. | We aim at investigating the role of blood born macrophages on the brain reaction to Trypanosoma cruzi infection in suckling rats. This infection provoked the appearance of numerous ED1(+) cells in the neural parenchyma and increased the amount of meningeal and perivascular ED2(+) macrophages. CD8(+) and NKR(+) cells al... | ['Analgesics, Non-Narcotic', 'Animals', 'Animals, Suckling', 'Cell Count', 'Central Nervous System', 'Central Nervous System Parasitic Infections', 'Chagas Disease', 'Clodronic Acid', 'Ectodysplasins', 'Enzyme-Linked Immunosorbent Assay', 'Immunization', 'Immunohistochemistry', 'Intercellular Adhesion Molecule-1', 'Int... | 15,020,064 | [['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['B01.050'], ['B01.050.050.293'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A08.186'], ['C01.207.205', 'C01.610.105', 'C10.228.228.205'], ['C01.610.752.300.900.200', 'C01.920.625'], ['D02.705.429.500.200'], ['D12.644.276.374.750.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Can we predict podiatric medical school grade point average using an admission screen? | BACKGROUND: Most medical school admission committees use cognitive and noncognitive measures to inform their final admission decisions. We evaluated using admission data to predict academic success for podiatric medical students using first-semester grade point average (GPA) and cumulative GPA at graduation as outcome ... | ['Aptitude Tests', 'College Admission Test', 'Educational Measurement', 'Educational Status', 'Humans', 'Multivariate Analysis', 'Podiatry', 'School Admission Criteria', 'Schools, Medical', 'Students, Medical', 'United States'] | 23,204,202 | [['F04.711.141'], ['I02.399.272'], ['I02.399'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['H02.696'], ['I02.399.750'], ['I02.783.495.552', 'N02.278.020.578'], ['M01.848.769.602'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Splenic volume may be a useful indicator of the protective effect of bevacizumab against oxaliplatin-induced hepatic sinusoidal obstruction syndrome. | AIMS: The aim of this study was to investigate the relationship between the use of bevacizumab (Bmab) in addition to oxaliplatin (OX), the development of sinusoidal obstruction syndrome (SOS) and the changes in splenic volume as an indicator of the protective effect of Bmab against OX-induced SOS.METHODS: Seventy-nine ... | ['Aged', 'Angiogenesis Inhibitors', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Bevacizumab', 'Colorectal Neoplasms', 'Female', 'Fluorouracil', 'Hepatic Veno-Occlusive Disease', 'Humans', 'Leucovorin', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Organ ... | 24,388,740 | [['M01.060.116.100'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.776.124.486.485.114.224.06... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of group A type 1 streptococcal M protein gene by a non-radioactive oligonucleotide detection method. | An oligonucleotide probe of 30 nucleotides length has been constructed, spanning the codons of amino acids 2 to 11 of the mature M1 protein of group A streptococci (Streptococcus pyogenes). It was labeled with digoxigenin-dUTP and visualized after hybridization with an anti-digoxigenin-antibody/alkaline phosphatase con... | ['Antigens, Bacterial', 'Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Base Sequence', 'Carrier Proteins', 'DNA Probes', 'DNA, Bacterial', 'Enzyme-Linked Immunosorbent Assay', 'Genes, Bacterial', 'Molecular Probe Techniques', 'Molecular Sequence Data', 'Streptococcus pyogenes'] | 2,082,158 | [['D23.050.161'], ['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D13.444.308.212'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Exchangeable GTP binding site of beta-tubulin. Identification of cysteine 12 as the major site of cross-linking by direct photoaffinity labeling. | After direct photoaffinity cross-linking of [3H]GTP to the beta-subunit of tubulin, followed by tryptic digestion and alkaline phosphatase treatment, we employed cis-diol-specific boronate gel chromatography and reversed-phase high-pressure liquid chromatography to purify a peptide containing most of the covalently bou... | ['Affinity Labels', 'Amino Acid Sequence', 'Animals', 'Binding Sites', 'Brain', 'Cattle', 'Chromatography, High Pressure Liquid', 'Cysteine', 'Free Radicals', 'Guanosine Triphosphate', 'Macromolecular Substances', 'Molecular Sequence Data', 'Molecular Weight', 'Peptide Fragments', 'Spectrometry, Mass, Fast Atom Bombard... | 8,416,920 | [['D27.720.470.410.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.300'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D01.339', 'D02.389'], ['D03.633.100.759.646.454.504',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Transcriptional regulation of lipoprotein lipase in the heart during development in the rat. | Lipoprotein lipase (LPL) is differentially expressed in fat and heart under a variety of physiological conditions, particularly during development. LPL activity, protein and mRNA levels have been shown to rise dramatically during the first three weeks of life. The mechanism responsible for these changes in LPL in the h... | ['Animals', 'Blotting, Northern', 'Gene Expression Regulation', 'Heart', 'Lipoprotein Lipase', 'Myocardium', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Transcription, Genetic'] | 8,048,956 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G05.308'], ['A07.541'], ['D08.811.277.352.100.430'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.111.873', 'G05.297.700']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A replicated climate change field experiment reveals rapid evolutionary response in an ecologically important soil invertebrate. | Whether species can respond evolutionarily to current climate change is crucial for the persistence of many species. Yet, very few studies have examined genetic responses to climate change in manipulated experiments carried out in natural field conditions. We examined the evolutionary response to climate change in a co... | ['Animals', 'Biological Evolution', 'Climate', 'Climate Change', 'Gene Frequency', 'Invertebrates', 'Polymorphism, Genetic', 'Soil', 'Temperature'] | 27,109,012 | [['B01.050'], ['G05.045', 'G16.075'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.175.374'], ['G05.330'], ['B01.050.500'], ['G05.365.795'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.71... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An ethnobotanical survey and antifungal activity of Piper guineense used for the treatment of fungal infections in West-African traditional medicine. | ETHNOBOTANICAL RELEVANCE: Piper guineense occurs commonly in West Africa where it is used for fungal infections instead of the costly and not always accessible conventional antifungals. Fungal, yeast-based diseases are common in West-Africa especially among those living with HIV/AIDS, and thus this study was performed ... | ['Adult', 'Africa, Western', 'Aged', 'Antifungal Agents', 'Candida', 'Cryptococcus neoformans', 'Ethnobotany', 'Female', 'Fruit', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Medicine, African Traditional', 'Microbial Sensitivity Tests', 'Middle Aged', 'Mycoses', 'Phytotherapy', 'Piper', 'Plant Extracts'... | 30,336,302 | [['M01.060.116'], ['Z01.058.290.190'], ['M01.060.116.100'], ['D27.505.954.122.136'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B01.300.381.258.366', 'B01.300.930.316.366'], ['H01.158.273.118.299'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.05... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and ... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Effects of age on dynamic accommodation. | Visual accommodation plays a critical role in one's visual perception and activities of daily living. Age-related accommodation loss poses an increased risk to older adults' safety and independence. Although extensive effort has been made towards understanding the effect of age on steady-state accommodation, dynamic as... | ['Accommodation, Ocular', 'Adaptation, Physiological', 'Adult', 'Age Factors', 'Aged', 'Aging', 'Analysis of Variance', 'Biomechanical Phenomena', 'Humans', 'Middle Aged', 'Multivariate Analysis', 'Reaction Time', 'Reading', 'Visual Perception', 'Young Adult'] | 20,582,770 | [['G14.010'], ['G07.025', 'G16.012.500'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Soluble HLA class I and class II concentrations in commercial immunoglobulin preparations. | Soluble HLA class I (sHLA-ABC) and class II (sHLA-RQP) molecules were quantitated in 16 commercially available immunoglobulin (Ig) preparations by enzyme-linked immunosorbent assays. Whereas three Ig preparations contained no detectable sHLA-ABC, all preparations showed concomitant sHLA-RQP molecules. There was a consi... | ['Enzyme-Linked Immunosorbent Assay', 'Histocompatibility Antigens Class I', 'Histocompatibility Antigens Class II', 'Humans', 'Immunoglobulins', 'Immunoglobulins, Intravenous'] | 1,574,801 | [['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.301.500.100', 'D23.050.705.552.100'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['B01.050.150.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurements of the middle cerebral artery in digital subtraction angiography and MR angiography. | BACKGROUND: The middle cerebral artery (MCA) has an individually varied anatomical type and course. Age and sex variability of MCA have not been completely defined. The aim was to define the range of normal values of widths and lengths of particular MCA segments, define age and sex variability, and compare the compatib... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Angiography, Digital Subtraction', 'Female', 'Humans', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged', 'Middle Cerebral Artery', 'Reference Values', 'Regional Blood Flow', 'Sex Factors'] | 17,507,888 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.500', 'E01.370.370.0... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[From surveillance to work-related accident prevention: the contribution of the ergonomics of the activity]. | Work-related accidents are complex phenomena determined by the work organization process, the dimensions of which are usually invisible to surveillance agents. The scope of this paper was a case study based on documentary evidence to analyze and compare the success of an intervention conducted at a meat processing and ... | ['Accidents, Occupational', 'Ergonomics', 'Humans', 'Population Surveillance'] | 23,099,767 | [['N06.850.135.240'], ['F02.784.412', 'J01.293.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Inequities in Access to Maternal Health Care in Enugu State: Implications for Universal Health Coverage to Meet Vision 2030 in Nigeria. | We explored the equity issues in access to maternal health services in Enugu State, Nigeria. We conducted a cross-sectional survey of 1,600 women who had babies within 6 months prior to the survey, drawn from four urban and rural local government areas in Enugu State of Nigeria, using structured questionnaire. Focus gr... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Female', 'Health Services Accessibility', 'Healthcare Disparities', 'Humans', 'Interviews as Topic', 'Maternal Health Services', 'Middle Aged', 'Nigeria', 'Prenatal Care', 'Quality of Health Care', 'Residence Characteristics', 'Socioeconomic Factors', 'State Medicine'... | 30,582,725 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.590.374.350', 'N05.300.430'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Molecular cloning and characterization of Brugia malayi thymidylate kinase. | Thymidylate kinase (TMK) is a potential chemotherapeutic target because it is directly involved in the synthesis of deoxythymidine triphosphate, which is an essential component for DNA synthesis. The gene encoding thymidylate kinase of Brugia malayi was amplified by PCR and expressed in Escherichia coli. The native mol... | ['Animals', 'Brugia malayi', 'Catalytic Domain', 'Cations, Divalent', 'Chromatography, Gel', 'Cloning, Molecular', 'Enzyme Activators', 'Enzyme Inhibitors', 'Enzyme Stability', 'Escherichia coli', 'Gene Expression', 'Hydrogen-Ion Concentration', 'Magnesium', 'Models, Molecular', 'Molecular Weight', 'Nucleoside-Phosphat... | 24,556,140 | [['B01.050'], ['B01.050.500.500.294.400.937.463.088.500'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D01.248.497.300.333'], ['E05.196.181.400.250'], ['E05.393.220'], ['D27.505.519.374'], ['D27.505.519.389'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Synchronous breast invasive ductal carcinoma and endometrial endometrioid adenocarcinoma: case report. | Diagnosis of synchronous primary cancers in one patient is a relatively rare event. The well-known synchronous primary cancers of women are combined ovarian and endometrial cancers, especially when both are the endometrioid cell type. Although breast cancer and endometrial cancer are two common female malignancies, the... | ['Adult', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Endometrioid', 'Endometrial Neoplasms', 'Female', 'Humans', 'Neoplasms, Multiple Primary', 'Premenopause'] | 21,518,130 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
BNP, troponin I, and YKL-40 as screening markers in extremely preterm infants at risk for pulmonary hypertension associated with bronchopulmonary dysplasia. | Bronchopulmonary dysplasia (BPD) is often complicated by pulmonary hypertension (PH). We investigated three biomarkers potentially suitable as screening markers for extremely preterm infants at risk of BPD-associated PH. In this prospective observational cohort study conducted in a tertiary neonatal intensive care unit... | ['Biomarkers', 'Bronchopulmonary Dysplasia', 'Chitinase-3-Like Protein 1', 'Demography', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Infant, Extremely Premature', 'Male', 'Natriuretic Peptide, Brain', 'Pulmonary Ventilation', 'Risk Factors', 'Troponin I'] | 27,760,764 | [['D23.101'], ['C08.381.520.750.500', 'C16.614.521.125'], ['D08.811.277.450.207.500', 'D12.776.503.070'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.703.520.520.500'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Hyperplasia of brown adipose tissue after chronic stimulation of beta 3-adrenergic receptor in rats. | When mammals are exposed to a cold environment for a long time, the capacity of nonshivering thermogenesis by brown adipose tissue (BAT) increases in association with the increased expression of some specific proteins and tissue hyperplasia, which are totally dependent on sympathetic innervation to this tissue. To clar... | ['Adipose Tissue, Brown', 'Adrenergic beta-Agonists', 'Animals', 'Cold Temperature', 'Female', 'Hyperplasia', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic, beta', 'Time Factors'] | 7,745,877 | [['A10.165.114.322'], ['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['C23.550.444'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bioethics: social work's response and training needs. | Hospital social workers (N = 255) from ten urban teaching hospitals in seven states were surveyed regarding their practice responses and training needs in bioethics. Responses to twenty-one practice situations in bioethics were analyzed in terms of levels of encountering ethical concerns, clinical participation and pre... | ['Adult', 'Aged', 'Attitude of Health Personnel', 'Bioethics', 'Curriculum', 'Female', 'Humans', 'Male', 'Middle Aged', 'Social Work', 'United States'] | 8,296,221 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['K01.752.566.479.045', 'N05.350.200'], ['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.792', 'N02.421.849'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
BDNF-, IGF-1- and GDNF-secreting human neural progenitor cells rescue amyloid â-induced toxicity in cultured rat septal neurons. | Alzheimer's disease (AD) is characterized by the depositions of amyloid-â (Aâ) proteins, resulting in a reduction of choline acetyltransferase (ChAT) activity of AD brain in the early stages of the disease. Several growth factors, including brain-derived neurotrophic factor (BDNF), insulin-like growth factor (IGF)-1 an... | ['Amyloid beta-Peptides', 'Animals', 'Brain-Derived Neurotrophic Factor', 'Cells, Cultured', 'Choline O-Acetyltransferase', 'Coculture Techniques', 'Female', 'Glial Cell Line-Derived Neurotrophic Factor', 'Humans', 'Insulin-Like Growth Factor I', 'Neurons', 'Peptide Fragments', 'Pregnancy', 'Rats', 'Rats, Transgenic', ... | 21,909,955 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A11.251'], ['D08.811.913.050.134.180'], ['E05.481.500.374'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Schistosoma mansoni: localization of calcium-detecting reagents in electron-lucent areas of specific preacetabular gland granules. | In an attempt to establish the exact location of calcium within the preacetabular glands of cercariae of Schistosoma mansoni, these larvae were exposed to reagents (potassium oxalate, potassium pyroantimonate, chloranilic acid, and silver nitrate) useful in the detection of calcium, and were subsequently observed with ... | ['Animals', 'Antimony', 'Calcium', 'Chloranil', 'Cytoplasmic Granules', 'Exocrine Glands', 'Indicators and Reagents', 'Larva', 'Microscopy, Electron', 'Oxalates', 'Potassium', 'Schistosoma mansoni', 'Silver Nitrate'] | 605,648 | [['B01.050'], ['D01.268.513.124', 'D01.268.556.050', 'D01.552.544.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.806.250.210'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A10.336'], ['D27.720.470.410'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E01.370.350.515.402', 'E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and antihypertensive activities of new 1,4-dihydropyridine containing nitroimidazolyl substituent with a nitrooxy group at the 3-ester position. | New analogues of nifedipine, in which the ortho nitrophenyl group of position 4 is replaced by 1-methyl-4-nitro-5-imidazolyl or 1-methyl-5-imidazolyl with a nitrooxy group at the 3-ester position were synthesized, and the antihypertensive activity of the compounds was examined by the tail-cuff method and compared with ... | ['Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Calcium Channel Blockers', 'Chemical Phenomena', 'Chemistry, Physical', 'Dihydropyridines', 'Esters', 'Indicators and Reagents', 'Male', 'Nitroimidazoles', 'Rats', 'Rats, Sprague-Dawley'] | 12,043,457 | [['B01.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['G02'], ['H01.181.529'], ['D03.383.725.203'], ['D02.241.400'], ['D27.720.470.410'], ['D02.640.672', 'D03.383.129.308.658'], ['B01.050.150.900.649.313.992.635.505.700... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The Protective Effect of N-Acetylcysteine on Ionizing Radiation Induced Ovarian Failure and Loss of Ovarian Reserve in Female Mouse. | Ionizing radiation may cause irreversible ovarian failure, which, therefore, calls for an effective radioprotective reagent. The aim of the present study was to evaluate the potential radioprotective effect of N-acetylcysteine (NAC) on ionizing radiation induced ovarian failure and loss of ovarian reserve in mice. Kun-... | ['Acetylcysteine', 'Animals', 'Apoptosis', 'Cell Proliferation', 'Disease Models, Animal', 'Embryo Implantation', 'Endometrium', 'Female', 'Humans', 'Mice', 'Ovarian Follicle', 'Ovarian Reserve', 'Primary Ovarian Insufficiency', 'Radiation, Ionizing', 'Radiation-Protective Agents'] | 28,607,932 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G08.686.784.170.104.500'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Survivor bias in Mendelian randomization analysis. | Mendelian randomization studies employ genotypes as experimental handles to infer the effect of genetically modified exposures (e.g. vitamin D exposure) on disease outcomes (e.g. mortality). The statistical analysis of these studies makes use of the standard instrumental variables framework. Many of these studies focus... | ['Adult', 'Aged', 'Bias', 'Biostatistics', 'Humans', 'Intermediate Filament Proteins', 'Mendelian Randomization Analysis', 'Middle Aged', 'Models, Statistical', 'Vitamin D'] | 29,028,924 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.150', 'N06.850.490.500'], ['E05.318.740.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593', 'D12.776.220.475'], ['E05.318.416.500'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['D04.2... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of LRRK2 in the regulation of dopamine receptor trafficking. | Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson's disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in the control of vesicle trafficking that in turn may regulate different ... | ['Animals', 'Cell Line, Tumor', 'Cell Membrane', 'Disease Models, Animal', 'Gene Expression Regulation', 'Gene Knock-In Techniques', 'Golgi Apparatus', 'Humans', 'Leucine-Rich Repeat Serine-Threonine Protein Kinase-2', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mutation', 'Neurons', 'Parkinson Disease', 'Protein Transport'... | 28,582,422 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.149'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.308'], ['E05.393.335.249'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.534', 'D12.776.637.750'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Somatic DNA alterations in endometriosis: high frequency of chromosome 17 and p53 loss in late-stage endometriosis. | PROBLEM: Genetic predisposition to endometriosis is well established, but the gene(s) involved largely remain unknown. Although endometriosis is considered a benign disease, it displays several features similar to malignancy: altered morphology, disregulated growth, invasion. We hypothesize endometriosis arises as resu... | ['Chromosomes, Human, Pair 17', 'DNA', 'Endometriosis', 'Female', 'Genes, p53', 'Humans', 'In Situ Hybridization, Fluorescence', 'Loss of Heterozygosity', 'Models, Genetic'] | 12,062,821 | [['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['D13.444.308'], ['C13.351.500.163'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical symptoms of hypogonadism after radical prostatectomy]. | This study checked whether the prevalence of hypogonadal symptoms [measured using the Aging Males' Symptoms Scale (AMSS)] after radical prostatectomy can give information about the prevalence of hypogonadism in this group of patients. Distribution of the level of complaints (no, mild, moderate or severe) on the AMSS af... | ['Adult', 'Aged', 'Germany', 'Humans', 'Hypogonadism', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prevalence', 'Prostatectomy', 'Risk Assessment', 'Risk Factors'] | 21,424,426 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.391.482'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E04.950.774.860.625'], ['E05.318.740.600.800... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Omeprazole compared with ranitidine once daily in the treatment of duodenal ulcer. | A double-blind randomized study in 230 Malaysian patients with duodenal ulcer was conducted to compare the proton-pump inhibitor, omeprazole 20 mg, given once daily in the morning, with ranitidine 300 mg, administered once daily at night. After 2 and 4 weeks of treatment, 222 and 220 patients, respectively, were evalua... | ['Adult', 'Aged', 'Double-Blind Method', 'Duodenal Ulcer', 'Female', 'Humans', 'Male', 'Middle Aged', 'Omeprazole', 'Ranitidine'] | 2,491,362 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.886.640.074.500', 'D03.383.725.024.500', 'D03.633.100.103.034.500']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Which are the best parameters to obtain proteins and malondialdehyde from a tear sample? | Predictive, preventive and personalized medicine (PPPM) is a current concept in healthcare based on the analysis of biomarkers through non-invasive methods. Biomarkers for inflammation and oxidative stress are especially used for screening. Quantification of tear total protein content is important to identify potential... | ['Adult', 'Chemistry, Analytic', 'Eye Proteins', 'Female', 'Healthy Volunteers', 'Humans', 'Male', 'Malondialdehyde', 'Specimen Handling', 'Tears'] | 31,028,749 | [['M01.060.116'], ['H01.181.309'], ['D12.776.306'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.047.700'], ['E01.370.225.998', 'E05.200.998'], ['A12.200.882']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
CellExcite: an efficient simulation environment for excitable cells. | BACKGROUND: Brain, heart and skeletal muscle share similar properties of excitable tissue, featuring both discrete behavior (all-or-nothing response to electrical activation) and continuous behavior (recovery to rest follows a temporal path, determined by multiple competing ion flows). Classical mathematical models of ... | ['Action Potentials', 'Algorithms', 'Animals', 'Computer Simulation', 'Heart Conduction System', 'Humans', 'Models, Biological', 'Myocytes, Cardiac', 'Nerve Net', 'Neurons', 'Software', 'User-Computer Interface'] | 18,387,205 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G17.035', 'L01.224.050'], ['B01.050'], ['L01.224.160'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['A08.511'], ['A08.675', 'A11.671'], ['L01.224.900'], ['L01.224.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prosthetic component relationship of the reverse Delta III total shoulder prosthesis in the transverse plane of the body. | The Delta III (DePuy International Ltd, Leeds, UK) reverse total shoulder prosthesis has provided a successful functional outcome in cuff tear arthropathy (CTA); however, internal and external rotation remain compromised. Positioning of the prosthetic components in the transverse plane has theoretically been suggested ... | ['Aged', 'Arthroplasty, Replacement', 'Female', 'Humans', 'Joint Prosthesis', 'Male', 'Middle Aged', 'Prosthesis Design', 'Range of Motion, Articular', 'Shoulder Joint'] | 18,455,444 | [['M01.060.116.100'], ['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400'], ['M01.060.116.630'], ['E05.320.550', 'E07.695.680'], ['E01.370.600.700', 'G11.427.760'], ['A02.835.583.748']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of a tricationic trigonal bipyramidal iron(IV) cyanide complex, with a very high reduction potential, and its iron(II) and iron(III) congeners. | Currently, there are only a handful of synthetic S = 2 oxoiron(IV) complexes. These serve as models for the high-spin (S = 2) oxoiron(IV) species that have been postulated, and confirmed in several cases, as key intermediates in the catalytic cycles of a variety of nonheme oxygen activating enzymes. The trigonal bipyra... | ['Cations', 'Iron', 'Molecular Conformation', 'Organometallic Compounds'] | 21,381,646 | [['D01.248.497.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G02.111.570.820'], ['D02.691']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Posterior reversible encephalopathy syndrome with tactile hallucinations secondary to dialysis disequilibrium syndrome. | We report what we believe is the first case of posterior reversible encephalopathy syndrome (PRES) secondary to dialysis disequilibrium syndrome (DDS) in patients in whom all other possible causes of PRES were excluded and in whom a transient episode of tactile hallucination also occurred. We believe that this case of ... | ['Acidosis', 'Adolescent', 'Antipsychotic Agents', 'Female', 'Hallucinations', 'Humans', 'Magnetic Resonance Imaging', 'Posterior Leukoencephalopathy Syndrome', 'Renal Dialysis', 'Renal Insufficiency, Chronic', 'Risk Factors', 'Severity of Illness Index', 'Time Factors', 'Tomography, X-Ray Computed', 'Treatment Outcome... | 24,821,163 | [['C18.452.076.176'], ['M01.060.057'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.228.140.631.500.500', 'C10.228.140.695.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A Case of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Treated Successfully with Multidisciplinary Therapy Including Preoperative Stereotactic Body Radiotherapy(SBRT)]. | A 61-year-old man untreated with hepatitis C virus presented to our hospital.He was diagnosed advanced hepatocellular carcinoma(HCC)with portal vein tumor thrombosis(PVTT).The hazy tumor was located in the left lobe, and the tumor thrombus extended into the left portal vein.The patient received stereotactic body radiot... | ['Carcinoma, Hepatocellular', 'Combined Modality Therapy', 'Hepatectomy', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Portal Vein', 'Radiosurgery', 'Thrombectomy', 'Venous Thrombosis'] | 29,394,731 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.186'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E01.370.350.567'], ['A07.015.908.670.567'], ['E02.815.530', 'E04.525.800.650... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Breast cancer mortality in Norway after the introduction of mammography screening. | An organized mammography screening program was gradually implemented in Norway during the period 1996-2004. Norwegian authorities have initiated an evaluation of the program. Our study focused on breast cancer mortality. Using Poisson regression, we compared the change in breast cancer mortality from before to during s... | ['Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Early Detection of Cancer', 'Female', 'Follow-Up Studies', 'Humans', 'Mammography', 'Mass Screening', 'Middle Aged', 'Norway'] | 22,532,175 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['E01.390.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Reduction of obesity and improvement in metabolic parameters by inhibition of intestinal lipases: current results with orlistat]. | Until recently, obesity did not play a major role in considerations of physicians and public health authorities. The impact of health-threatening overweight was so far considered only as a risk factor for various other serious illnesses, such as hypertension, diabetes mellitus, hyperuricemia, elevated blood lipid level... | ['Adult', 'Aged', 'Austria', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Enzyme Inhibitors', 'Female', 'Humans', 'Lactones', 'Lipase', 'Male', 'Middle Aged', 'Obesity', 'Orlistat', 'Treatment Outcome', 'Weight Loss'] | 9,879,390 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.542.088'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540'], ['D08.811.277.352.100.400'], ['M01.060.116.630'], ['C18... | ['Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Orbital venous approach to the cavernous sinus: an analysis of the facial and orbital venous system. | Carotid-cavernous fistulas are abnormal communications between the internal carotid artery and the cavernous sinus produced by a rupture of the wall of the carotid artery or one of its branches into the sinus. Extradural branches of the internal or external carotid arteries may communicate with the cavernous sinus, pro... | ['Aged', 'Arteriovenous Fistula', 'Carotid Artery, Internal', 'Cavernous Sinus', 'Face', 'Female', 'Humans', 'Orbit', 'Veins'] | 7,810,953 | [['M01.060.116.100'], ['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['A07.015.114.186.200.230'], ['A07.015.908.224.334'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.690'], ['A07.015.908... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
PMS777, a bis-interacting ligand for PAF receptor antagonism and AChE inhibition, attenuates PAF-induced neurocytotoxicity in SH-SY5Y cells. | (1) HIV-1 and viral proteins-evoked chronic brain inflammation, which is characterized by microglial activation, is the pivotal neuropathogenesis of HIV-1-associated dementia (HAD). Platelet-activating factor (PAF), mainly released from activated microglia and acts as a high potent inflammatory mediator and a neurotoxi... | ['Acetylcholinesterase', 'Apoptosis', 'Calcium', 'Caspase Inhibitors', 'Cell Line, Tumor', 'Cell Survival', 'Cholinesterase Inhibitors', 'Cyclooxygenase 2', 'Furans', 'Gene Expression Regulation', 'Humans', 'Intracellular Space', 'Ligands', 'Neurons', 'Neurotoxins', 'Platelet Activating Factor', 'Platelet Membrane Glyc... | 17,712,622 | [['D08.811.277.352.100.170.176'], ['G04.146.954.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.389.745.325.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['D08.811.600.720.750'], ['D03.383.312'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatic lipase gene expression is upregulated by a cystine-rich diet in male but not in female rats. | Male and female rats fed a cystine-rich diet (5% L-cystine) became hypercholesterolemic after 2 months, with 2-fold higher cholesterol levels carried mainly by the HDL1 and HDL2 lipoprotein fractions. Post-heparin lipoprotein lipase activity was increased in male rats only (60%, P < 0.01), while hepatic lipase (HL) act... | ['Animals', 'Cholesterol, HDL', 'Cystine', 'Diet', 'Female', 'Gene Expression', 'Hypercholesterolemia', 'Lipase', 'Liver', 'Male', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Sex Factors', 'Up-Regulation'] | 7,893,737 | [['B01.050'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['G07.203.650.240'], ['G05.297'], ['C18.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[I131 in blood samples: management in the laboratory]. | OBJECTIVES: Patients treated by (131)I may require blood sampling in the days following its administration. We investigated the safety of such samples in terms of radioactivity and the possible disturbance of the analyses by these "131I-spiked" samples.METHOD: 1) The radioactivity of blood samples from 131I-treated pat... | ['Drug Contamination', 'Environmental Pollution', 'Goiter', 'Humans', 'Hyperthyroidism', 'Iodine Radioisotopes', 'Occupational Exposure', 'Personnel, Hospital', 'Risk Factors', 'Thyroid Neoplasms'] | 16,230,298 | [['N06.850.360'], ['N06.850.460'], ['C19.874.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['N06.850.460.350.600'], ['M01.526.485.740', 'N02.360.740'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.70... | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Upregulation of Jun and Fos family members and permanent JNK activity lead to constitutive AP-1 activation in Theileria-transformed leukocytes. | Theileria parasitises bovine leukocytes and transforms them into proliferating, metastatic tumours, where the infection resembles a leukaemia-like disease. We have studied the signal transduction pathways leading to activation of the transcription factor AP-1 in different transformed leukocytes. Parasite infection lead... | ['Animals', 'B-Lymphocytes', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cattle', 'Cells, Cultured', 'Enzyme Activation', 'Gene Expression Regulation, Enzymologic', 'JNK Mitogen-Activated Protein Kinases', 'Leukocytes', 'Lymphocyte Activation', 'Macrophages', 'Mitogen-Activated Protein Kinases', 'Phosphorylation',... | 9,747,972 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['G02.111.263', 'G03.328'], ['G05.308.320'], ['D08.811.9... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insight into the structural and biological relevance of the T/R transition of the N-terminus of the B-chain in human insulin. | The N-terminus of the B-chain of insulin may adopt two alternative conformations designated as the T- and R-states. Despite the recent structural insight into insulin-insulin receptor (IR) complexes, the physiological relevance of the T/R transition is still unclear. Hence, this study focused on the rational design, sy... | ['Aminoisobutyric Acids', 'Circular Dichroism', 'Crystallography, X-Ray', 'Humans', 'Insulin', 'Models, Molecular', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular'] | 24,819,248 | [['D02.241.081.114.968.249', 'D12.125.070.075', 'D12.125.190.055'], ['E05.196.867.151'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['E05.196.867.519.550']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement and modeling of intrinsic transcription terminators. | The reliable forward engineering of genetic systems remains limited by the ad hoc reuse of many types of basic genetic elements. Although a few intrinsic prokaryotic transcription terminators are used routinely, termination efficiencies have not been studied systematically. Here, we developed and validated a genetic ar... | ['Escherichia coli', 'Models, Genetic', 'RNA Folding', 'Terminator Regions, Genetic', 'Transcription Termination, Genetic'] | 23,511,967 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.599.395.397'], ['G01.154.709', 'G02.111.570.820.486.718', 'G02.111.750', 'G05.360.580.718'], ['G02.111.570.080.689.810', 'G05.360.080.689.810', 'G05.360.340.024.340.137.750.830'], ['G02.111.873.687', 'G05.297.700.687']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases. | Multifunctional silica nanoparticles decorated with fluorescent and sulfonamide carbonic anhydrase (CA) inhibitors were prepared and investigated as multivalent enzyme inhibitors against the cytosolic isoforms hCA I and II and the transmembrane tumor-associated ones hCA IX and XII. Excellent inhibitory effects were obs... | ['Antigens, Neoplasm', 'Antineoplastic Agents', 'Carbonic Anhydrase I', 'Carbonic Anhydrase II', 'Carbonic Anhydrase Inhibitors', 'Carbonic Anhydrases', 'Cell Line, Tumor', 'Cytosol', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Humans', 'Isoenzymes', 'Molecular Structure', 'Nanoparticles', 'Neoplasms', 'S... | 25,965,260 | [['D23.050.285'], ['D27.505.954.248'], ['D08.811.520.241.300.150.100'], ['D08.811.520.241.300.150.200'], ['D27.505.519.389.200'], ['D08.811.520.241.300.150'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Theoretical and hands-on guidance from dental hygienists promotes good oral health in elderly people living in nursing homes, a pilot study. | OBJECTIVES: Oral health in nursing homes for elderly is often unsatisfactory, and oral health education to nursing staff has not shown sufficient results why there is need for novel approaches. The aim of the study was to trial a new oral healthcare educational programme and to evaluate the effects on residents' oral h... | ['Aged', 'Aged, 80 and over', 'Attitude of Health Personnel', 'Dental Hygienists', 'Dental Plaque', 'Female', 'Gingival Diseases', 'Health Promotion', 'Hemorrhage', 'Humans', 'Male', 'Nursing Homes', 'Nursing Staff', 'Oral Health', 'Oral Hygiene', 'Periodontal Index', 'Pilot Projects'] | 29,651,816 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.050', 'N05.300.100'], ['M01.526.485.067.105.376', 'N02.360.067.105.376'], ['C07.793.208.377'], ['C07.465.714.258'], ['I02.233.332.445', 'N02.421.726.407.579'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.825.610'], ['M01.526.485.68... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparison of macroscopic models of excitation and force propagation in the heart. | Computer aided simulations of the heart provide knowledge of phenomena, which are commonly neither visible nor measurable with current techniques. This knowledge can be applied e.g. in cardiologic diagnosis and therapy. A variety of models was created to reconstruct cardiac processes, e.g. electrical propagation and fo... | ['Animals', 'Biophysical Phenomena', 'Biophysics', 'Computer Simulation', 'Electrocardiography', 'Heart', 'Heart Conduction System', 'Humans', 'Models, Cardiovascular', 'Models, Theoretical', 'Myocardial Contraction', 'Nonlinear Dynamics'] | 12,451,821 | [['B01.050'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['L01.224.160'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161'], ['E05.599'], ['G09.330.580', 'G11.427.494.570'], ['E05.599.850', 'H01.548.675']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Searching for genomic variants in IGF2 and CDKN1C in Silver-Russell syndrome patients. | Silver-Russell syndrome (SRS) is a heterogeneous syndrome with evidence for a substantial role of genetic factors in its etiology. Apart from other specific clinical features, severe intrauterine and postnatal growth retardation are the dominant characteristics of SRS. Therefore, studies on the genetic basis of the dis... | ['Base Sequence', 'Cyclin-Dependent Kinase Inhibitor p57', 'DNA Primers', 'Gene Frequency', 'Genetic Testing', 'Genetic Variation', 'Germany', 'Growth Disorders', 'Humans', 'Insulin-Like Growth Factor II', 'Molecular Sequence Data', 'Mutation', 'Nuclear Proteins', 'Sequence Analysis, DNA', 'Syndrome'] | 15,234,339 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.644.360.225.700', 'D12.776.167.187.700', 'D12.776.476.225.700', 'D12.776.624.776.355.700'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.330'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Association of FGFR1 with ERá Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ | Purpose:FGFR1 amplification occurs in approximately 15% of estrogen receptor-positive (ER+) human breast cancers. We investigated mechanisms by which FGFR1 amplification confers antiestrogen resistance to ER+ breast cancer.Experimental Design: ER+ tumors from patients treated with letrozole before surgery were subjecte... | ['Animals', 'Breast Neoplasms', 'Cell Line, Tumor', 'Disease Models, Animal', 'Drug Resistance, Neoplasm', 'Estrogen Receptor Modulators', 'Estrogen Receptor alpha', 'Female', 'Fibroblast Growth Factors', 'Gene Amplification', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice', 'Molecular Targeted Therapy', 'Ne... | 28,751,448 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.984.395'], ['D06.347.360', 'D27.505.696.399.450.360'], ['D12.776.826.750.350.174'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['G05.308.250', 'G05.365.590.3... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Properties of human blood monocytes. I. CD91 expression and log orthogonal light scatter provide a robust method to identify monocytes that is more accurate than CD14 expression. | BACKGROUND: This study was designed to improve identification of human blood monocytes by using antibodies to molecules that occur consistently on all stages of monocyte development and differentiation.METHODS: We examined blood samples from 200 healthy adults without clinically diagnosed immunological abnormalities by... | ['Adult', 'Antibodies', 'Biomarkers', 'Cell Separation', 'Female', 'Flow Cytometry', 'Healthy Volunteers', 'Hematologic Tests', 'Humans', 'Leukocytes, Mononuclear', 'Light', 'Lipopolysaccharide Receptors', 'Low Density Lipoprotein Receptor-Related Protein-1', 'Male', 'Scattering, Radiation'] | 24,591,168 | [['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.101'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.34... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: pharmacological properties of synaptic currents. | Whole cell patch-clamp recordings were made from substantia gelatinosa neurons in the thick slice of the adult rat spinal cord, which retained an attached dorsal root to study the pharmacological properties of spontaneous and primary afferent fibre-evoked synaptic currents. The majority of substantia gelatinosa neurons... | ['2-Amino-5-phosphonovalerate', '6-Cyano-7-nitroquinoxaline-2,3-dione', 'Animals', 'Bicuculline', 'Electric Stimulation', 'Electrodes', 'Electrophysiology', 'In Vitro Techniques', 'Male', 'Neurons', 'Neurons, Afferent', 'Quinoxalines', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord', 'Strychnine', 'Substantia Gelatinosa'... | 8,098,516 | [['D12.125.070.950.100', 'D12.125.740.025'], ['D03.633.100.857.160'], ['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['E05.723.402'], ['E07.305.250'], ['H01.158.344.528', 'H01.158.782.236'], ['E05.481'], ['A08.675', 'A11.671'], ['A08.675.650', 'A11.671.650'], ['D03.633.100.857'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Neonatal delivery weight and risk of future maternal diabetes. | OBJECTIVE: To investigate associations between neonatal delivery weight and future risk of maternal type 1 or type 2 diabetes.METHODS: Data included in the Swedish Medical Birth Registry and Swedish National Diabetes Registry were merged to include all women born during 1930-1989; patients with pre-existing diabetes or... | ['Adult', 'Birth Weight', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Infant, Newborn', 'Odds Ratio', 'Parturition', 'Postpartum Period', 'Pregnancy', 'Proportional Hazards Models', 'Registries', 'Regression Analysis', 'Risk Factors', 'Sweden'] | 28,980,304 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Two new rearranged abietane diterpenoids from tropical Isodon coetsa. | Two new rearranged abietane diterpenoids, sincoetsin A (1) and sincoetsin B (2), were isolated from the aerial part of Isodon coetsa (Buth-Ham ex D.Don) Hara collected in Singapore, and their structures were determined by spectroscopic methods, especially 2D NMR techniques. | ['Abietanes', 'Isodon', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Plant Components, Aerial', 'Plants, Medicinal', 'Singapore'] | 17,145,653 | [['D02.455.426.559.847.723.040', 'D02.455.849.291.040', 'D04.615.723.040'], ['B01.650.940.800.575.912.250.583.520.362'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['A18.024'], ['B01.650.560'], ['Z01.252.145.774']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Gender differences in dentists' working practices and job satisfaction. | OBJECTIVES: To describe the working practices and level of job satisfaction of male and female dentists.METHODS: A nationwide postal survey of all dentists holding an annual practising certificate in New Zealand (response rate 78.1%).RESULTS: The mean number of hours worked per week was 29.1 for female and 36.0 for mal... | ['Adult', 'Age Factors', 'Attitude of Health Personnel', 'Career Choice', 'Child', 'Child Care', 'Child Rearing', 'Choice Behavior', 'Dentists', 'Dentists, Women', 'Education, Dental, Continuing', 'Female', 'Humans', 'Job Satisfaction', 'Male', 'Middle Aged', 'New Zealand', 'Ownership', 'Partnership Practice, Dental', ... | 18,313,826 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100.050', 'N05.300.100'], ['F02.463.785.373.346.400'], ['M01.060.406'], ['I01.880.787.293.360', 'N02.421.088'], ['F01.318'], ['F02.463.785.373.346'], ['M01.526.485.330', 'N02.360.330'], ['M01.526.485.330.310', 'M01.975.310', 'N02.360.330.310'], ['I02.358.2... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A pilot study of 2 years of interferon treatment in patients with chronic delta hepatitis. | High dose interferon treatment for 1 year is the only established treatment for chronic hepatitis D, but it is associated with a high relapse rate after treatment discontinuation. In this study, patients were treated with 10 MU interferon alpha 2b, thrice weekly for 2 years. Twenty-three patients were recruited and 15 ... | ['Adult', 'Alanine Transaminase', 'Antiviral Agents', 'Biopsy', 'Female', 'Hepatitis D', 'Hepatitis Delta Virus', 'Histocytochemistry', 'Humans', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Pilot Projects', 'RNA, Viral', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain Reaction'] | 17,927,618 | [['M01.060.116'], ['D08.811.913.477.700.100'], ['D27.505.954.122.388'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C01.925.440.450', 'C01.925.782.450', 'C06.552.380.705.450'], ['B04.265.270', 'B04.450.411', 'B04.820.48... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Anticoagulant prescribing practices and anesthetic interventions among anticoagulated pregnant patients: a retrospective study. | BACKGROUND: The peripartum management of anticoagulated patients poses important challenges for obstetric anesthesiologists, especially when deciding to perform neuraxial block. However, there is limited evidence evaluating anticoagulant prescribing practices and neuraxial block utilization in this setting. Our objecti... | ['Adult', 'Anesthesia, Epidural', 'Anesthesia, Obstetrical', 'Anticoagulants', 'Cohort Studies', 'Delivery, Obstetric', 'Drug Prescriptions', 'Enoxaparin', 'Female', 'Heparin, Low-Molecular-Weight', 'Humans', "Practice Patterns, Physicians'", 'Pregnancy', 'Retrospective Studies'] | 24,910,353 | [['M01.060.116'], ['E03.155.086.131'], ['E03.155.364'], ['D27.505.954.502.119'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.520.252'], ['E02.319.307', 'N02.421.668.778.500'], ['D09.698.373.400.300.200'], ['D09.698.373.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arterial grafts do not counteract target vessel occlusion. | OBJECTIVES: Grafted, non-occluded coronary arteries might contribute substantially to the myocardial blood supply and serve as a basis for vascular collateralization which preserves the myocardium in the event of graft occlusion. Early studies indicated that grafting with saphenous vein, but not internal mammary arteri... | ['Adult', 'Aged', 'Chi-Square Distribution', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Vessels', 'Female', 'Graft Occlusion, Vascular', 'Humans', 'Male', 'Mammary Arteries', 'Middle Aged', 'Radial Artery', 'Saphenous Vein', 'Vascular Patency'] | 23,956,270 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['A07.015.114.269'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Barley RNA viromes in six different geographical regions in Korea. | Barley is a kind of cereal grass belonging to the family Poaceae. To examine viruses infecting winter barley in Korea, we carried out a comprehensive study of barley RNA viromes using next-generation sequencing (NGS). A total of 110 barley leaf samples from 17 geographical locations were collected. NGS followed by exte... | ['High-Throughput Nucleotide Sequencing', 'Hordeum', 'Phylogeny', 'Plant Diseases', 'Plant Leaves', 'Plant Viruses', 'Potyviridae', 'Republic of Korea'] | 30,185,900 | [['E05.393.760.319'], ['B01.650.940.800.575.912.250.822.481'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G15.610'], ['A18.024.812'], ['B04.715'], ['B04.715.635', 'B04.820.578.782'], ['Z01.252.474.557.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
The effects of hypoxemia with progressive acidemia on fetal renal function in sheep. | In order to determine the effects of fetal hypoxemia on renal blood flow, glomerular filtration rate (GFR) and urethral and urachal urine output, we examined the effects of 3 h maternally-induced (9% O2, 3% CO2, 88% N2) fetal hypoxaemia on 10 chronically-instrumented fetal sheep between 127-135 days of gestation. Fetal... | ['Animals', 'Blood Gas Analysis', 'Blood Pressure', 'Female', 'Glomerular Filtration Rate', 'Heart Rate, Fetal', 'Hydrogen-Ion Concentration', 'Hypoxia', 'Kidney', 'Pregnancy', 'Renal Circulation', 'Sheep', 'Urine'] | 2,640,226 | [['B01.050'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.390.400.300', 'G08.852.357'], ['G09.330.380.500.430'], ['G02.300'], ['C23.888.852.079'], ['A05.810.453'], ['G08.686.784.769'], ['G08.852.725', 'G09.330.100.812'], ['B01.050.150.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differentiation of oxyntic cells during early ontogenesis in the bovine. | The origin and the differentiation of oxyntic cells in fetal bovine abomasum were investigated using transmission electron and light microscopic methods. In the oxyntic gland region oxyntic cell precursors and immature oxyntic cells appear as early as at the end of the first trimester of gestation--much earlier than de... | ['Abomasum', 'Animals', 'Cattle', 'Cell Differentiation', 'Fetus', 'Gastric Mucosa', 'Microscopy, Electron', 'Parietal Cells, Gastric'] | 14,758,846 | [['A13.869.106'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G04.152'], ['A16.378'], ['A03.556.875.875.440', 'A10.615.550.291'], ['E01.370.350.515.402', 'E05.595.402'], ['A03.556.875.875.440.708', 'A10.615.550.291.650', 'A11.436.708']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gastric control of duodenal electric activity--the function of the gastroduodenal junction. | An investigation was made into the links between electric activity of antral and of duodeno-jejunal musculature in different functional conditions. The function of the gastroduodenal junction in this linking mechanism was analysed. The following observations were made: (a) in the absence of gastric stimulation, the slo... | ['Animals', 'Cats', 'Duodenum', 'Electric Stimulation', 'Electrodes', 'Female', 'Male', 'Muscle Contraction', 'Stomach', 'Temperature'] | 58,601 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E05.723.402'], ['E07.305.250'], ['G11.427.494'], ['A03.556.875.875'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Type 2 spinocerebellar ataxia: an experience in psychological rehabilitation]. | INTRODUCTION: Psychological rehabilitation in patients with neurodegenerative disorders helps to improve their quality of life and provide the most suitable approach to their disease. There are no records of this type of treatment being used in type 11 spinocerebellar ataxia.OBJECTIVES: To evaluate the efficacy of grou... | ['Adult', 'Anxiety', 'Attitude', 'Cuba', 'Depression', 'Female', 'Humans', 'Male', 'Psychotherapy, Group', 'Quality of Life', 'Spinocerebellar Ataxias'] | 11,785,023 | [['M01.060.116'], ['F01.470.132'], ['F01.100'], ['Z01.107.084.900.225', 'Z01.639.880.225'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.754.864.581'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['C10.228.140.252.190.530', 'C10.228.140.252.700.700', 'C10.228.854.787.875', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Correlation of objective measure of trunk motion and muscle function with low-back disability ratings. | A study was undertaken to examine relations among some objective and subjective measures of low-back-related disability in a group of 41 low-back pain patients and in seven pain-free control subjects. Subjective measures of disability were obtained by Oswestry patient questionnaires. Oswestry disability score related s... | ['Activities of Daily Living', 'Adult', 'Back Pain', 'Disability Evaluation', 'Electromyography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Movement', 'Muscles', 'Surveys and Questionnaires'] | 2,958,944 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['C23.888.592.612.107'], ['E01.370.400'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['A02.633', 'A10.690'], ['E05.318.308.980', 'N05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Combined in situ analysis of metabolic and myoelectrical changes associated with electrically induced fatigue. | Electrical muscle stimulation (Mstim) at a low or high frequency is associated with failure of force production, but the exact mechanisms leading to fatigue in this model are still poorly understood. Using 31P magnetic resonance spectroscopy (31PMRS), we investigated the metabolic changes in rabbit tibialis anterior mu... | ['Acidosis', 'Action Potentials', 'Animals', 'Electric Stimulation', 'Electrophysiology', 'Energy Metabolism', 'Hydrogen-Ion Concentration', 'Magnetic Resonance Spectroscopy', 'Muscle Contraction', 'Muscle Fatigue', 'Phosphocreatine', 'Phosphorus', 'Rabbits', 'Reaction Time'] | 12,819,224 | [['C18.452.076.176'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E05.723.402'], ['H01.158.344.528', 'H01.158.782.236'], ['G03.295'], ['G02.300'], ['E05.196.867.519'], ['G11.427.494'], ['G11.427.550'], ['D12.125.373.603', 'D12.125.740.675'], ['D01.268.666'], ['B01.050.150.900.649.313.968.700']... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of monovalent cations on Na+/Ca2+ exchange and ATP-dependent Ca2+ transport in synaptic plasma membranes. | Two Ca2+ transport systems were investigated in plasma membrane vesicles isolated from sheep brain cortex synaptosomes by hypotonic lysis and partial purification. Synaptic plasma membrane vesicles loaded with Na+ (Na+i) accumulate Ca2+ in exchange for Na+, provided that a Na+ gradient (in leads to out) is present. Age... | ['Adenosine Triphosphate', 'Animals', 'Biological Transport', 'Calcimycin', 'Calcium', 'Cations, Monovalent', 'Monensin', 'Potassium', 'Sheep', 'Sodium', 'Synaptic Membranes'] | 6,409,998 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G03.143'], ['D03.633.100.221.173'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300.459'], ['D03.383.312.600'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.050.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Long-term follow-up of children with neurogenic bladder and artificial urinary sphincter]. | MATERIALS AND METHODS: Since 1986 an artificial urinary sphincter was implanted in 16 children (13 males and 3 females) 4 to 12 years old (median age 9) in order to solve their urinary incontinence. Mean age at implantation was 9 years. In 10 children (63%) only the implant procedure of artificial sphincter was perform... | ['Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Postoperative Complications', 'Reoperation', 'Time Factors', 'Urinary Bladder', 'Urinary Bladder Fistula', 'Urinary Bladder, Neurogenic', 'Urinary Incontinence', 'Urinary Sphincter, Artificial'] | 10,570,854 | [['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E04.690'], ['G01.910.857'], ['A05.810.890'], ['C12.706.881.312', 'C12.777.829.733', 'C13.351.875.881.312', 'C13.351.968.82... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of reduced insulin-like growth factor-1/insulin signaling on aging in mammals: novel findings. | Growth hormone deficiency or resistance resulting from spontaneous or experimentally produced mutations in laboratory mice delay aging and increase lifespan. Alterations in insulin-like growth factor-1 (IGF-1) and insulin signaling emerged as likely mechanisms linking growth hormone and aging, and increased longevity w... | ['Animals', 'Growth Hormone', 'Insulin', 'Insulin Receptor Substrate Proteins', 'Insulin-Like Growth Factor I', 'Intracellular Signaling Peptides and Proteins', 'Longevity', 'Mice', 'Mice, Knockout', 'Phosphoproteins', 'Pregnancy-Associated Plasma Protein-A', 'Receptor, IGF Type 1', 'Signal Transduction'] | 18,346,217 | [['B01.050'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D12.644.360.024.301', 'D12.776.157.057.045', 'D12.776.476.024.382'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D12.644.360', 'D12.776.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solution structure of an oncogenic mutant of Cdc42Hs. | Cdc42Hs(F28L) is a single-point mutant of Cdc42Hs, a member of the Ras superfamily of GTP-binding proteins, that facilitates cellular transformation brought about by an increased rate of cycling between GTP and GDP [Lin, R., et al. (1997) Curr. Biol. 7, 794-797]. Dynamics studies of Cdc42Hs(F28L)-GDP have shown increas... | ['Binding Sites', 'GTP-Binding Proteins', 'Guanosine Diphosphate', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Oncogene Proteins', 'Point Mutation', 'Protein Conformation', 'Protein-Tyrosine Kinases', 'Recombinant Proteins', 'Solutions'] | 16,489,751 | [['G02.111.570.120'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D03.633.100.759.646.454.340', 'D13.695.667.454.340', 'D13.695.827.426.340'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['E05.599.595'], ['D12.776.624.664'], ['G05.365.590.675'], ['G02.111.570.820.709'], ['D08.811.913.696.620.682.725'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rituximab in combination with chemotherapy for the treatment of chronic lymphocytic leukaemia in clinical practice. | OBJECTIVES: This study was conducted to investigate the real-world effectiveness and tolerability of rituximab-containing chemoimmunotherapies, which have become the standard of care for chronic lymphocytic leukaemia (CLL), particularly for physically fit patients. Furthermore, current treatment patterns in clinical pr... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Drug Resistance, Neoplasm', 'Female', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prospective Studies', 'Recurrence', 'Rituximab', 'Survival Analysis', 'Treatment Outcome'] | 29,393,986 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20.683.515.528.080.125'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.372.500.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. | Fungal tRNA ligase (Trl1) rectifies RNA breaks with 2',3'-cyclic-PO4 and 5'-OH termini. Trl1 consists of three catalytic modules: an N-terminal ligase (LIG) domain; a central polynucleotide kinase (KIN) domain; and a C-terminal cyclic phosphodiesterase (CPD) domain. Trl1 enzymes found in all human fungal pathogens are ... | ['Amino Acid Sequence', 'Base Sequence', 'Candida albicans', 'Catalytic Domain', 'Crystallography, X-Ray', 'Guanosine Triphosphate', 'Models, Molecular', 'Nucleotidases', "Polynucleotide 5'-Hydroxyl-Kinase", 'Protein Binding', 'Protein Conformation', 'Protein Folding', 'RNA Ligase (ATP)', 'Structure-Activity Relationsh... | 31,722,405 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Pathological and clinical aspects of bronchial carcinoid tumor. The authors' own case reports]. | Data (radiological, endoscopic, histological, clinical and surgical) are presented on 21 subjects with pulmonary carcinoid tumour encountered in the Turin University Chest Surgery Centre in 1980-1985. All patients were subjected to fibrobronchoscopy which revealed the tumour in 18 cases (14 were given multiple biopsies... | ['Adult', 'Aged', 'Bronchi', 'Bronchial Neoplasms', 'Carcinoid Tumor', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pneumonectomy'] | 3,808,387 | [['M01.060.116'], ['M01.060.116.100'], ['A04.411.125'], ['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.620', 'E04.928.600.600']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis of magnetic epichlorohydrin cross-linked carboxymethyl cellulose microspheres and their adsorption behavior for methylene blue. | Epichlorohydrin cross-linked carboxymethyl cellulose microspheres (ECH/CMC) obtained by inverse suspension method and magnetic Fe3O4 nanoparticles encasing the ECH/CMC microspheres (M-ECH/CMC) obtained by two different methods were successfully prepared and compared. Their structures and morphologies were analyzed usin... | ['Adsorption', 'Carboxymethylcellulose Sodium', 'Cross-Linking Reagents', 'Epichlorohydrin', 'Humans', 'Methylene Blue', 'Microscopy, Electron, Scanning', 'Microspheres', 'Spectroscopy, Fourier Transform Infrared', 'Waste Water', 'Water Pollutants, Chemical', 'X-Ray Diffraction'] | 27,768,520 | [['G01.030', 'G02.020'], ['D09.698.365.180.663.329'], ['D27.720.470.410.210'], ['D02.355.291.411.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.369.517', 'D03.633.300.783.517'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E07.565'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['D20.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The prevalence of antibodies reactive with Campylobacter jejuni in the serum of homosexual men. | Samples of serum from 187 homosexual and 169 heterosexual men were examined by means of an indirect immunofluorescent antibody test for the presence of antibody reactive with Campylobacter jejuni. Antibody of the IgG class was detected in the serum of 19 (10.2 per cent) and 15 (8.9 per cent) homo- and heterosexual men ... | ['Adolescent', 'Adult', 'Antibodies', 'Campylobacter Infections', 'Campylobacter fetus', 'Feces', 'Fluorescent Antibody Technique', 'Homosexuality', 'Humans', 'Male', 'Middle Aged', 'Social Class', 'Time Factors'] | 6,389,711 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C01.150.252.400.177'], ['B03.440.180.325', 'B03.660.150.235.250.500.220'], ['A12.459'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
New species of Acanthocinini Blanchard, 1845 (Coleoptera, Cerambycidae) from Rond?nia state, Brazil and notes on some genera. | Three new species of Acanthocinini (Coleoptera, Cerambycidae) from Rond?nia State, Brazil, are described and illustrated: Leptostylus obrienorum, Nyssodrysina maculosa and Urgleptes curvatum. We also present a brief generic discussion about these genera. | ['Animals', 'Ascaridida', 'Brazil', 'Coleoptera', 'Spiders'] | 30,313,892 | [['B01.050'], ['B01.050.500.500.294.400.500'], ['Z01.107.757.176'], ['B01.050.500.131.617.720.500.500.375'], ['B01.050.500.131.166.803']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Pictorial depth and related constancy effects as a function of recognition. | It is argued that while pictorial cues must be fundamental in the perception of an extended ground plane in daily life (and, by definition, in the perception of depth in pictures), the traditional pictorial cues such as perspective or texture gradients are neither a necessary nor a sufficient basis for it. That they ar... | ['Art', 'Cues', 'Depth Perception', 'Female', 'Form Perception', 'Humans', 'Judgment', 'Male', 'Optical Illusions', 'Photography', 'Size Perception'] | 628,579 | [['K01.093'], ['F02.463.425.234'], ['F02.463.593.200', 'F02.463.593.778.255'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['F02.463.593.446.659'], ['E01.370.350.600', 'E05.712'], ['F02.463.593.725', 'F02.463.593.778.794']] | ['Humanities [K]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The conformation of purified Toxoplasma gondii SAG1 antigen, secreted from engineered Pichia pastoris, is adequate for serorecognition and cell proliferation. | A truncated form of SAG1, the immunodominant surface antigen of Toxoplasma gondii, has been produced in the methylotrophic yeast, Pichia pastoris. By construction, the recombinant protein lacks C-terminal residues 308-336 which, in native SAG1, encompass the glycosylphosphatidylinositol anchorage site. Secretion of anc... | ['Amino Acid Sequence', 'Animals', 'Antigens, Protozoan', 'Cell Division', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Leukocytes, Mononuclear', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Pichia', 'Protein Engineering', 'Protein Folding', 'Protozoan Proteins', 'Rabbits', 'Survival Rate', '... | 9,866,865 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.293'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
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