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Febrile convulsions in northern Japan: a quantitative and qualitative analysis of EEG and clinical findings. | In an attempt to describe the characteristics of febrile convulsions (FC) 133 children with a history of FC were checked neurologically at health centers in northern Japan. Using categorical data from principal component analysis, family history of FC, recurrence and body temperature prior to convulsion, EEG disorders,... | ['Cerebral Cortex', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Dominance, Cerebral', 'Electroencephalography', 'Epilepsy', 'Evoked Potentials', 'Female', 'Humans', 'Japan', 'Male', 'Seizures, Febrile'] | 1,887,765 | [['A08.186.211.200.885.287.500'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['F02.830.297', 'G11.561.225'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['C10.597.742.571... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Femoral bone mineral density and bone mineral content in bromocriptine-treated pregnant and lactating rats. | Since hyperprolactinemia was found to induce osteopenia in the metaphysis of long bone in non-mated female rats, pregnant and lactating rats with sustainedly high plasma prolactin (PRL) levels might also exhibit some changes in their long bones. We performed a longitudinal study in pregnant, lactating and post-weaning ... | ['Absorptiometry, Photon', 'Animals', 'Bone Density', 'Bromocriptine', 'Female', 'Femur', 'Lactation', 'Pregnancy', 'Pregnancy, Animal', 'Prolactin', 'Rats', 'Rats, Sprague-Dawley'] | 19,760,135 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['B01.050'], ['G11.427.100'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['A02.835.232.043.150'], ['G08.686.523', 'G08.686.702.500'], ['G08.686.784.769'], ['G08.686.784.769.498'], ['D06.472.699.322.576.773', 'D06.472.699.631.525.525', 'D12.644... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential effects of prostacyclin and iloprost in the isolated carotid artery of the guinea-pig. | The effects on membrane potential of prostacyclin and iloprost were compared in smooth muscle cells of the guinea pig carotid artery. Both prostacyclin and iloprost induced hyperpolarization of the smooth muscle cells. In the presence of (3R)-3-(4-fluorophenyl-sulfonamido)-1,2,3,4-tetrahydro-9-carbazolepropanoic acid (... | ['Animals', 'Carotid Arteries', 'Dose-Response Relationship, Drug', 'Endothelium, Vascular', 'Epoprostenol', 'Glyburide', 'Guinea Pigs', 'Iloprost', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Muscle, Smooth, Vascular'] | 11,525,776 | [['B01.050'], ['A07.015.114.186'], ['G07.690.773.875', 'G07.690.936.500'], ['A07.015.700.500', 'A10.272.491.355'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['B01.050.150.900.649.313.992.550'], ['D10.251.355.255.550.775.125', 'D23.469.050.175.725.775... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharyngoesophageal reconstruction using free jejunal interposition grafts. | Forty patients underwent pharyngoesophageal reconstruction with a free jejunal interposition graft (FJIG). Three categories of disease were treated: (1) primary upper aerodigestive tract carcinomas, (2) recurrent carcinomas, and (3) benign pharyngoesophageal stenosis. There were no intraoperative graft failures. Postop... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Esophageal Stenosis', 'Esophagoplasty', 'Female', 'Follow-Up Studies', 'Glottis', 'Humans', 'Hypopharyngeal Neoplasms', 'Jejunum', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', 'Oropharyngeal Neoplasms', 'Palliative Care', 'Pharynx', 'Postoperative ... | 2,413,833 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['C06.405.117.544'], ['E04.210.355'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of cranberry juice on pharmacokinetics of beta-lactam antibiotics following oral administration. | Cranberry juice consumption is often recommended along with low-dose oral antibiotics for prophylaxis for recurrent urinary tract infection (UTI). Because multiple membrane transporters are involved in the intestinal absorption and renal excretion of beta-lactam antibiotics, we evaluated the potential risk of pharmacok... | ['Administration, Oral', 'Adult', 'Amoxicillin', 'Anti-Bacterial Agents', 'Beverages', 'Cefaclor', 'Drug Interactions', 'Female', 'Humans', 'Vaccinium macrocarpon', 'Young Adult', 'beta-Lactams'] | 19,398,645 | [['E02.319.267.100'], ['M01.060.116'], ['D02.065.589.099.750.750.050.050', 'D02.886.108.750.750.050.050', 'D03.633.100.300.750.750.050.050'], ['D27.505.954.122.085'], ['G07.203.100', 'J02.200'], ['D02.065.589.099.249.200.155', 'D02.886.665.074.200.155', 'D03.633.100.300.249.200.155'], ['G07.690.773.968'], ['B01.050.150... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Long-term regression of experimental endometriosis in a rat model treated with local application of levonorgestrel-loaded biodegradable microspheres. | BACKGROUND: A previous study demonstrated that local application of levonorgestrel-loaded polylactic acid microspheres (LNG microspheres) resulted in significant regression of endometriotic cysts in a rabbit model for 6 months without disturbing the metabolic parameters or ovarian function. In order to investigate the ... | ['Absorbable Implants', 'Animals', 'Biocompatible Materials', 'Body Weight', 'Disease Models, Animal', 'Endometriosis', 'Female', 'Humans', 'Levonorgestrel', 'Microspheres', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Estrogen', 'Treatment Outcome'] | 22,563,024 | [['E07.695.025'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Changes in the healthcare profession: from denial to acceptance. | As the government and other factors seem to be increasingly gaining control over the healthcare industry, many hospital managers and staff feel as if they're increasingly losing control over their jobs and their futures. Indeed, some administrators and physicians are experiencing a kind of stress that may be seen as a ... | ['Adaptation, Psychological', 'Attitude of Health Personnel', 'Facility Regulation and Control', 'Grief', 'Hospital Administrators', 'Nursing Staff, Hospital', 'Physicians', 'Social Change', 'United States'] | 10,107,972 | [['F01.058'], ['F01.100.050', 'N05.300.100'], ['N03.706.280', 'N05.700.300'], ['F01.470.142.110'], ['M01.526.070.490.490', 'M01.526.485.430.490', 'M01.526.485.740.380', 'N02.360.430.490', 'N02.360.740.380'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['M01.526.485.810', 'N02.3... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Lung transplantation--present status worldwide and in the Czech Republic]. | Lung transplantation has evolved to a standard treatment modality for patients suffering from end-stage lung diseases and it provides very good short- and satisfactory long-term survival. Accepted indications for lung transplantation include chronic obstructive pulmonary disease (COPD) and other causes of emphysema (i.... | ['Czech Republic', 'Humans', 'Lung Transplantation'] | 14,746,218 | [['Z01.542.248.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928.600.495', 'E04.936.450.495']] | ['Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Wolbachia-Based Dengue Virus Inhibition Is Not Tissue-Specific in Aedes aegypti. | BACKGROUND: Dengue fever, caused by the dengue virus (DENV), is now the most common arbovirus transmitted disease globally. One novel approach to control DENV is to use the endosymbiotic bacterium, Wolbachia pipientis, to limit DENV replication inside the primary mosquito vector, Aedes aegypti. Wolbachia that is natura... | ['Aedes', 'Animals', 'Antibiosis', 'Dengue', 'Dengue Virus', 'Fat Body', 'Malpighian Tubules', 'Mosquito Vectors', 'Organ Specificity', 'Salivary Glands', 'Symbiosis', 'Viral Load', 'Virus Replication', 'Wolbachia'] | 27,855,218 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['G06.550.050', 'G16.062'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['B04.820.578.344.350.270'], ['A13.365'], ['A13.574'], ['N06.850.335.188.100.500.500', 'N06.850.520.203.375.100.500.500'], ['G07.65... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Two kynurenine aminotransferases in human brain. | Using Tris-acetate buffer rather than conventional phosphate buffer, it was possible to detect two distinct proteins capable of producing the neuroinhibitory brain metabolite kynurenic acid (KYNA) from L-kynurenine in human brain tissue. The two kynurenine aminotransferases (KATs), arbitrarily termed 'KAT I' and 'KAT I... | ['Amino Acids', 'Brain', 'Humans', 'Hydrogen-Ion Concentration', 'Isoelectric Focusing', 'Kinetics', 'Lyases', 'Male', 'Transaminases'] | 2,029,638 | [['D12.125'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.196.401.663', 'E05.301.300.663'], ['G01.374.661', 'G02.111.490'], ['D08.811.520'], ['D08.811.913.477.700']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In situ replication of immediate dendritic cell (DC) precursors contributes to conventional DC homeostasis in lymphoid tissue. | The developmental biology of dendritic cells (DC) under physiological conditions remains unclear. In this study, we show that mouse CD11c(+) MHC class II(-)lineage(-) cells are immediate precursors of conventional DC and are widely distributed in both bone marrow and lymphoid tissues. These precursors have a high clona... | ['Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Division', 'Cell Proliferation', 'Cells, Cultured', 'Clone Cells', 'Dendritic Cells', 'Homeostasis', 'Leukocyte Common Antigens', 'Lymphoid Tissue', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Signal Transduction', 'Spl... | 16,751,363 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A11.251.353'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['G07.410'], ['D08.811.277.352.650.775.400.100.500'... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma. | Neural stem cells and progenitor cells migrate selectively to tumor loci in vivo. We exploited the tumor-tropic properties of HB1.F3.C1 cells, an immortalized cell line derived from human fetal telencephalon, to deliver the cDNA encoding a secreted form of rabbit carboxylesterase (rCE) to disseminated neuroblastoma tum... | ['Adenoviridae', 'Animals', 'Antineoplastic Agents, Phytogenic', 'Camptothecin', 'Carboxylesterase', 'Cell Line, Tumor', 'Combined Modality Therapy', 'DNA, Complementary', 'Disease-Free Survival', 'Genetic Therapy', 'Humans', 'Irinotecan', 'Mice', 'Neuroblastoma', 'Prodrugs', 'Telencephalon', 'Transduction, Genetic', '... | 17,210,679 | [['B04.280.030'], ['B01.050'], ['D27.505.954.248.179'], ['D03.132.151'], ['D08.811.277.352.100.100'], ['A11.251.210.190', 'A11.251.860.180'], ['E02.186'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Green-to-red photoconvertible mEosFP-aided live imaging in plants. | Numerous subcellular-targeted probes have been created using a monomeric green-to-red photoconvertible Eos fluorescent protein for understanding the growth and development of plants. These probes can be used to create color-based differentiation between similar cells, differentially label organelle subpopulations, and ... | ['Arabidopsis', 'Cell Tracking', 'Fluorescence Recovery After Photobleaching', 'Green Fluorescent Proteins', 'Image Processing, Computer-Assisted', 'Luminescent Proteins', 'Plant Cells', 'Plants, Genetically Modified'] | 22,264,534 | [['B01.650.940.800.575.912.250.157.100'], ['E01.370.225.500.373', 'E01.370.350.557.500', 'E05.200.500.373', 'E05.242.373'], ['E05.196.712.516.600.393'], ['D12.776.532.265'], ['L01.224.308'], ['D12.776.532'], ['A11.750'], ['B01.650.520', 'B05.620.600']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Parents' experiences of participation in physical activities for children with cerebral palsy - protecting and pushing towards independence. | PURPOSE: To explore how parents of children with cerebral palsy (CP) experience their child's participation in physical activities and to identify facilitators and barriers for being physically active and reducing sedentary behaviour.METHODS: Twenty-five parents of sixteen children, aged 8-11 years old with CP, with va... | ['Adult', 'Cerebral Palsy', 'Child', 'Disabled Children', 'Exercise', 'Female', 'Focus Groups', 'Humans', 'Interviews as Topic', 'Male', 'Parents'] | 28,187,693 | [['M01.060.116'], ['C10.228.140.140.254'], ['M01.060.406'], ['M01.150.200'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Purification of active RNA polymerase I from yeast. | Eukaryotic cells employ at least three nuclear, DNA-dependent RNA polymerase systems for the synthesis of cellular RNA. RNA polymerases I, II, and III primarily produce rRNA, mRNA, and tRNA, respectively. In a rapidly growing cell, most RNA synthesis is devoted to production of the translation machinery, with rRNA synt... | ['In Vitro Techniques', 'Molecular Biology', 'RNA Polymerase I', 'Saccharomyces cerevisiae'] | 25,665,570 | [['E05.481'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650'], ['D08.811.913.696.445.735.270.750'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anthropometric indices of fat distribution and cardiometabolic risk in Parkinson's disease. | BACKGROUND & AIMS: To investigate the association between anthropometric indices of body fat distribution and cardiometabolic risk factors in a population of Parkinson's disease (PD) patients.METHODS & RESULTS: One hundred and fifty-seven PD patients (57.3% males) were studied measuring: waist circumference (WC), waist... | ['Adipose Tissue', 'Adiposity', 'Aged', 'Anthropometry', 'Blood Glucose', 'Body Fat Distribution', 'Body Mass Index', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Humans', 'Hypertension', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Nutrition Assessment', 'Obesity', 'Parkinson Disease', 'Prevalence', 'Risk Facto... | 21,906,920 | [['A10.165.114'], ['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.062', 'G02.111.130.134', 'G03.180.134', 'G07.100.049.134'], ['E01.370.600.115... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Postmortem screening for fatty acid oxidation disorders by analysis of Guthrie cards with tandem mass spectrometry in sudden unexpected death in infancy. | A protocol was developed for the detection of fatty acid oxidation disorders (FOD) in cases of sudden unexpected death in infancy (SUDI). Tandem mass spectrometry blood acylcarnitine analysis of Guthrie card blood spots was performed. In the first 5 years, 1.2% of Oregon's 247 SUDI cases were identified with FOD, 2 wit... | ['Acyl-CoA Dehydrogenase, Long-Chain', 'Fatty Acids', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Mass Spectrometry', 'Sudden Infant Death'] | 12,461,502 | [['D08.811.682.660.150.150', 'D12.776.331.102'], ['D10.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.196.566'], ['C23.550.260.322.625', 'C23.550.260.657.500']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of hybridized liposome by novel modification with some polyethyleneglycol-lipids. | This study is about hybridized liposome contained doxorubicin (Hy-LDOX) that has dual properties of stability in blood and incorporation in tumor cells. We used two kinds of polyethyleneglycol-lipids which are 1-monomethoxypolyethyleneglycol-2,3-distearoylglycerol (PEG-DSG) with an alkyl anchor and cholesterol-PEG (PEG... | ['Animals', 'Drug Carriers', 'Lipids', 'Liposomes', 'Male', 'Mice', 'Mice, Inbred DBA', 'Polyethylene Glycols', 'Xenograft Model Antitumor Assays'] | 19,429,278 | [['B01.050'], ['D26.255.260', 'E02.319.300.380'], ['D10'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.500', 'B01.050.150.900.649.313.992.635.505.500.400.500'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.74... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Phage infection, transfection and transformation of Mycobacterium avium complex and Mycobacterium paratuberculosis. | Mycobacterium avium complex strains and Mycobacterium paratuberculosis are closely related intracellular pathogens affecting humans and animals. M. avium complex infections are a leading cause of morbidity and mortality in AIDS patients, and M. paratuberculosis is the agent of Johne's disease in ruminants. Genetic mani... | ['AIDS-Related Opportunistic Infections', 'Amikacin', 'Animals', 'Bacteriophages', 'Humans', 'Kanamycin', 'Kinetics', 'Luciferases', 'Microbial Sensitivity Tests', 'Mycobacterium avium Complex', 'Mycobacterium avium subsp. paratuberculosis', 'Plasmids', 'Recombinant Proteins', 'Species Specificity', 'Transfection', 'Tr... | 7,773,411 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['D09.408.051.476.060'], ['B01.050'], ['B04.123'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.408.051.476'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.517', 'D12.776.532.510']... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The performance of ultrasound physiotherapy machines in Lothian Region, Scotland, 1992. | Eighty-five ultrasound therapy machines in use in Lothian Region, Scotland were tested for performance and their recalibration was expedited where necessary. The performance characteristics reported are the temporal average acoustic output power, the treatment frequency, pulse timing and treatment timer accuracy. Consi... | ['Calibration', 'Electric Power Supplies', 'Equipment Design', 'Equipment Safety', 'Humans', 'Maintenance', 'Physical Therapy Modalities', 'Scotland', 'Time Factors', 'Transducers', 'Ultrasonic Therapy', 'Ultrasonics'] | 8,085,291 | [['E05.978.155'], ['E07.305.124'], ['E05.320'], ['E05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.628'], ['E02.779', 'E02.831.535'], ['Z01.542.363.766'], ['G01.910.857'], ['E07.305.812'], ['E02.565.280.945'], ['H01.671.031.849']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Attachment, autonomy, and multifinality in adolescent internalizing and risky behavioral symptoms. | A diathesis-stress interaction model is used to describe multifinality in adolescent internalizing and risky behavioral outcomes. Problematic behavior associated with adolescent insecure preoccupation (a diathesis) was expected to interact with the level of maternal autonomous discourse (a stressor) to predict specific... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Female', 'Humans', 'Male', 'Mother-Child Relations', 'Object Attachment', 'Personal Autonomy', 'Risk-Taking'] | 12,931,837 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290.170'], ['F02.739.794.624'], ['F02.600', 'I01.880.604.473.380.500', 'K01.752.566.479.830.650', 'N03.706.437.380.500', 'N05.350.958.650'], ['F01.145.722']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Analysis of health-related quality of life in children with immune thrombocytopenia and their parents using the kids' ITP tools. | The diagnosis, treatment, and prognosis of immune trombocytopenic purpura (ITP) have been extensively studied, but data on its effect on health-related quality of life in children remain sparse. To shed more light on this issue, we administered the Kids' ITP Tools (KIT) questionnaire to 17 children with ITP attending a... | ['Adolescent', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Humans', 'Infant', 'Male', 'Parents', 'Platelet Count', 'Purpura, Thrombocytopenic, Idiopathic', 'Quality of Life', 'Retrospective Studies', 'Surveys and Questionnaires'] | 22,215,093 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of obstructive sleep apneas on transcutaneous oxygen pressure in control infants, siblings of sudden infant death syndrome victims, and near miss infants: comparison with the effects of central sleep apneas. | In order to investigate the effects of obstructive sleep apneas upon transcutaneous PO2 75 polysomnograms, recorded during night sessions in 25 control infants, 25 siblings, and 25 near miss for sudden infant death syndrome (SIDS) infants were studied. These observations were compared with the decreases in transcutaneo... | ['Female', 'Humans', 'Infant, Newborn', 'Male', 'Oxygen', 'Partial Pressure', 'Pregnancy', 'Respiration', 'Sleep Apnea Syndromes', 'Sudden Infant Death', 'Time Factors'] | 7,145,537 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D01.268.185.550', 'D01.362.670'], ['G01.374.715.714'], ['G08.686.784.769'], ['G09.772.705'], ['C08.618.085.852', 'C10.886.425.800.750'], ['C23.550.260.322.625', 'C23.550.260.657.500'], ['G01.910.857']] | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Simultaneous recording of Indo-1 fluorescence and Na+/Ca2+ exchange current reveals two components of Ca2(+)-release from sarcoplasmic reticulum of cardiac atrial myocytes. | Simultaneous measurements of intracellular Ca2(+)-concentration ([Ca2+]i) using Indo-1 and the current generated by electrogenic Na+/Ca2(+)-exchange (INaCa) have been performed on atrial myocytes from hearts of adult guinea-pigs. Whereas the fluorescence-measurements provide information on global [Ca2+]i, InaCa which i... | ['Animals', 'Calcium', 'Carrier Proteins', 'Cells, Cultured', 'Cytosol', 'Electric Conductivity', 'Fluorescence', 'Guinea Pigs', 'Heart Atria', 'Indoles', 'Membrane Potentials', 'Myocardium', 'Sarcolemma', 'Sarcoplasmic Reticulum', 'Sodium-Calcium Exchanger'] | 2,261,988 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157'], ['A11.251'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G01.358.500.249.277'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.992.550'], ['A07.541.358'], ['D03.633.100.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plagiarism in research: a survey of African medical journals. | OBJECTIVES: To examine whether regional biomedical journals in Africa had policies on plagiarism and procedures to detect it; and to measure the extent of plagiarism in their original research articles and reviews.DESIGN: Cross sectional survey.SETTING AND PARTICIPANTS: We selected journals with an editor-in-chief in A... | ['Africa', 'Biomedical Research', 'Cross-Sectional Studies', 'Editorial Policies', 'Humans', 'Journalism, Medical', 'Periodicals as Topic', 'Plagiarism', 'Software'] | 30,413,518 | [['Z01.058'], ['H01.770.644.145'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.737.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.737.498.550'], ['L01.178.682.829.678'], ['L01.737.684'], ['L01.224.900']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Developmental expression of ACE2 in the SHR kidney: a role in hypertension? | The abnormal development of the intrarenal renin-angiotensin system (RAS) is thought contribute to adult-onset hypertension in the spontaneously hypertensive rat (SHR). Angiotensin-converting enzyme 2 (ACE2) is a novel enzyme with complementary actions to that of ACE. Recent studies have shown that ACE2 expression is r... | ['Angiotensin-Converting Enzyme 2', 'Animals', 'Gene Expression Regulation', 'Hypertension, Renal', 'Kidney', 'Peptidyl-Dipeptidase A', 'RNA, Messenger', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY'] | 16,710,353 | [['D08.811.277.656.350.245.042'], ['B01.050'], ['G05.308'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['A05.810.453'], ['D08.811.277.656.350.350.687'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.300'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anxiety symptom presentations in Han Chinese and Euro-Canadian outpatients: is distress always somatized in China? | BACKGROUND: Cultural variations in the relative emphasis on somatic versus psychological symptoms of distress are a common topic in cultural psychopathology. The most well-known example involves people of Chinese heritage, who are found to emphasize somatic symptoms in presenting depression as compared with people of W... | ['Adolescent', 'Adult', 'Affect', 'Anxiety', 'Anxiety Disorders', 'Asian Continental Ancestry Group', 'Canada', 'China', 'Cultural Characteristics', 'Depression', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Middle Aged', 'Outpatients', 'Psychotic Disorders', 'Stress, Psychological', 'Surveys and Questionnaires'... | 21,794,924 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['F01.470.132'], ['F03.080'], ['M01.686.508.200'], ['Z01.107.567.176'], ['Z01.252.474.164'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['F01.145.126.350'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.643.630'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Deactivation and unfolding are uncoupled in a bacterial lipase exposed to heat, low pH and organic solvents. | The lipase from Burkholderia glumae (BGL) was incubated at variable temperature, pH and concentration of organic solvents, and the decrease of enzymatic activity was compared to changes in the molecular structure as monitored by ESI-mass spectrometry. We observed that deactivation is not strictly related to structural ... | ['Burkholderia', 'Circular Dichroism', 'Enzyme Activation', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Lipase', 'Mass Screening', 'Protein Folding', 'Solvents'] | 19,428,729 | [['B03.660.075.090.688.100'], ['E05.196.867.151'], ['G02.111.263', 'G03.328'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.300'], ['D08.811.277.352.100.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.44... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Bernese periacetabular osteotomy (Ganz procedure). First experience]. | PURPOSE OF THE STUDY: Developmental dysplasia of the hip (DDH), treated either conservatively or surgically, may result in a dysplastic acetabulum. To treat this after bone maturation is completed, Bernese periacetabular osteotomy, also known as the Ganz procedure, has recently been used as the method of choice at our ... | ['Acetabulum', 'Adolescent', 'Adult', 'Child', 'Female', 'Hip Dislocation, Congenital', 'Humans', 'Male', 'Osteotomy', 'Young Adult'] | 19,755,053 | [['A02.835.232.043.825.108'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.555.580'], ['M01.060.116.815']] | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computing the skeleton of coronary arteries in cineangiograms. | In this paper we describe techniques to determine the skeleton of coronary arteries and to measure their medically significant geometric properties (such as boundaries and orientations) in cineangiograms. We use these geometric properties for segmentation, i.e., for separating the image of the arteries from the backgro... | ['Algorithms', 'Cineangiography', 'Coronary Angiography', 'Coronary Vessels', 'Humans', 'Image Interpretation, Computer-Assisted', 'Mathematics', 'Radiographic Image Interpretation, Computer-Assisted'] | 3,769,471 | [['G17.035', 'L01.224.050'], ['E01.370.350.700.060.190', 'E01.370.370.050.190'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of septal grafts on acetylcholine release from rat hippocampus after 192 IgG-saporin lesion. | The cholinergic inputs to the rat hippocampus were lesioned by intraseptal injections of 192 IgG-saporin. After 15 days, fetal septal cells were grafted into the hippocampus. Thirteen months later, hippocampal acetylcholine (ACh) release was studied by microdialysis. Lesioning reduced basal ACh release (100%) to 20% of... | ['Acetylcholine', 'Acetylcholinesterase', 'Animals', 'Antibodies, Monoclonal', 'Brain Diseases', 'Cholinergic Agents', 'Hippocampus', 'Immunotoxins', 'Male', 'N-Glycosyl Hydrolases', 'Rats', 'Rats, Long-Evans', 'Ribosome Inactivating Proteins, Type 1', 'Saporins', 'Septum Pellucidum', 'Serotonin'] | 12,675,132 | [['D02.092.211.111'], ['D08.811.277.352.100.170.176'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C10.228.140'], ['D27.505.519.625.120', 'D27.505.696.577.120'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.776.124.790.651.114.580.45... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Convergent validity of the aberrant behavior checklist and behavior problems inventory with people with complex needs. | The current study aimed to replicate and extend Rojahn et al. [Rojahn, J., Aman, M. G., Matson, J. L., & Mayville, E. (2003). The aberrant behavior checklist and the behavior problems inventory: Convergent and divergent validity. Research in Developmental Disabilities, 24, 391-404] by examining the convergent validity ... | ['Adolescent', 'Adult', 'Child', 'Developmental Disabilities', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Psychomotor Agitation', 'Regression Analysis', 'Reproducibility of Results', 'Self-Injurious Behavior', 'Severity of Illness Index', 'Stereotyped Behavior', 'Surveys and Questionnaires'] | 17,110,081 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['F03.625.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['C10.597.350.600', 'C10.597.606.881.700', 'C23.888.592.350.600', 'C23.888.592.604.882.700', 'F01.700.875.700'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.370... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
HCMV-DNA is detected more frequently than infectious virus in blood leucocytes of immunocompromised patients: a direct comparison of culture-immunofluorescence and PCR for detection of HCMV in clinical specimens. | In two studies comparing detection of human cytomegalovirus (HCMV) in 118 patients (93 of whom were immunocompromised) by the polymerase chain reaction (PCR) and virus isolation using either early antigen detection by culture-immunofluorescence or conventional cytopathic effect, DNA-PCR was found to be the most sensiti... | ['Base Sequence', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'DNA, Viral', 'Fluorescent Antibody Technique', 'Humans', 'Immunocompromised Host', 'Leukocytes', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Virology'] | 1,335,481 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['D13.444.308.568'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Non-invasive in vivo characterization of microclimate pH inside in situ forming PLGA implants using multispectral fluorescence imaging. | The pH inside drug delivery systems influences directly the physical and chemical behavior of its ingredients specifically their solubility and stability. These properties significantly affect the release performance of the formulations as well as the pharmacological effect. Therefore, the determination of the microcli... | ['Animals', 'Benzopyrans', 'Drug Carriers', 'Drug Implants', 'Electron Spin Resonance Spectroscopy', 'Hydrogen-Ion Concentration', 'Lactic Acid', 'Magnetic Resonance Imaging', 'Mice', 'Optical Imaging', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Solubility', 'Solvents'] | 24,503,251 | [['B01.050'], ['D03.383.663.283', 'D03.633.100.150'], ['D26.255.260', 'E02.319.300.380'], ['D26.255.210.315'], ['E05.196.867.519.274'], ['G02.300'], ['D02.241.511.459.450'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.589', 'E05.642'], ['D05.750.728.780', 'D25.720.728.780', 'J01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Electron acceptors in photosynthetic reaction centers from Rhodopseudomonas spheroides]. | Using optical differential spectroscopy and EPR, a parallel study of light-induced electron transfer between the primary (X1) and secondary (X2) quinone-like acceptors in the preparations of reaction centers (RC) isolated from bacterial chromatophore membranes with sodium dodecyl sulfate was carried out. The data from ... | ['Bacterial Chromatophores', 'Bacteriochlorophylls', 'Electron Spin Resonance Spectroscopy', 'Electron Transport', 'Kinetics', 'Light', 'Oxidation-Reduction', 'Photosynthesis', 'Rhodobacter sphaeroides', 'Spectrophotometry', 'Temperature'] | 227,482 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of clozapine on ethanol withdrawal syndrome in rats. | AIMS: Co-morbid substance use in schizophrenic patients is common, and an important factor affects the outcome of disease. On the other hand, drug dependence is a predictive factor for psychosis. Alcohol is one of the most frequently abused psychoactive substances and may contribute psychotic symptoms in several condit... | ['Alcohol Drinking', 'Animals', 'Clozapine', 'Ethanol', 'Male', 'Motor Activity', 'Rats', 'Rats, Wistar', 'Stereotyped Behavior', 'Substance Withdrawal Syndrome'] | 18,579,515 | [['F01.145.317.269'], ['B01.050'], ['D03.633.300.240.220'], ['D02.033.375'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['F01.145.896'], ['C25.775.835', 'F03.900.825']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Four GABAergic interneurons impose feeding restraint in Drosophila. | Feeding is dynamically regulated by the palatability of the food source and the physiological needs of the animal. How consumption is controlled by external sensory cues and internal metabolic state remains under intense investigation. Here, we identify four GABAergic interneurons in the Drosophila brain that establish... | ['Animals', 'Animals, Genetically Modified', 'Drosophila', 'Feeding Behavior', 'Female', 'GABAergic Neurons', 'Gastrointestinal Tract', 'Interneurons'] | 24,991,960 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A08.675.289', 'A11.671.285'], ['A03.556'], ['A08.675.358', 'A11.671.358']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Conformation changes in the mechanism of cryoprecipitation of human monoclonal immunoglobulin M]. | The role of conformational changes in the mechanism of cryoprecipitation of human monoclonal immunoglobulin M (IgM) was studied. It was demonstrated that the variable moiety of the Fab-region of cryo-IgM has a site which comprises 5 to 6 charged amino acid residues. This site is responsible for intermolecular electrost... | ['Calorimetry, Differential Scanning', 'Chemical Phenomena', 'Chemical Precipitation', 'Chemistry, Physical', 'Cryoglobulins', 'Humans', 'Immunoglobulin M', 'Microscopy, Electron', 'Protein Conformation'] | 3,447,628 | [['E05.196.131.310', 'E05.196.370.310'], ['G02'], ['E05.196.150', 'G02.159'], ['H01.181.529'], ['D12.776.124.486.485.900.225', 'D12.776.124.790.651.900.225', 'D12.776.377.715.548.900.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii. | The hypothetical protein predicted by the open reading frame MJ0055 of Methanococcus jannaschii was expressed in a recombinant Escherichia coli strain under the control of a synthetic gene optimized for translation in an eubacterial host. The recombinant protein catalyzes the formation of the riboflavin precursor 3,4-d... | ['Amino Acid Sequence', 'Base Sequence', 'Magnetic Resonance Spectroscopy', 'Methanococcus', 'Molecular Sequence Data', 'Riboflavin', 'Sugar Phosphates'] | 12,200,440 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.867.519'], ['B02.200.538.525.500'], ['L01.453.245.667'], ['D03.633.100.733.315.650', 'D03.633.300.507.650', 'D08.211.474.650', 'D23.767.405.650'], ['D09.894']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
GAPLINC is a predictor of poor prognosis and regulates cell migration and invasion in osteosarcoma. | Gastric adenocarcinoma predictive long intergenic non-coding (GAPLINC) is a novel long non-coding RNA (lncRNA) and has been found to function as an oncogenic lncRNA in gastric cancer, colorectal cancer, and bladder cancer. The expression status and biological function of GAPLINC in osteosarcoma are still unknown. Thus,... | ['Adolescent', 'Adult', 'Biomarkers, Tumor', 'Cell Movement', 'Cell Proliferation', 'Child', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Hyaluronan Receptors', 'Male', 'Neoplasm Invasiveness', 'Osteosarcoma', 'Prognosis', 'RNA, Long Noncoding', 'Young Adult'] | 30,177,521 | [['M01.060.057'], ['M01.060.116'], ['D23.101.140'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['M01.060.406'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750.281', 'D12.776.543.550.200.625.144', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Population differentiation as a test for selective sweeps. | Selective sweeps can increase genetic differentiation among populations and cause allele frequency spectra to depart from the expectation under neutrality. We present a likelihood method for detecting selective sweeps that involves jointly modeling the multilocus allele frequency differentiation between two populations... | ['Alleles', 'Europe', 'Gene Frequency', 'Humans', 'Polymorphism, Single Nucleotide', 'Population Groups', 'Probability'] | 20,086,244 | [['G05.360.340.024.340.030'], ['Z01.542'], ['G05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.598'], ['M01.686', 'N01.224.708'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600']] | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Parent-child interactions in autism: characteristics of play. | Although the literature on parent-child interactions in young children with autism has examined dyadic style, synchrony, and sustained engagement, the examination of parental skill in sustaining and developing play skills themselves has not been targeted. This study examined the extent to which parents of young childre... | ['Attention', 'Autistic Disorder', 'Case-Control Studies', 'Child, Preschool', 'Female', 'Humans', 'Imitative Behavior', 'Infant', 'Male', 'Parent-Child Relations', 'Play and Playthings', 'Social Behavior'] | 23,382,513 | [['F02.830.104.214'], ['F03.625.164.113.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.510'], ['M01.060.703'], ['F01.829.263.370.290'], ['I03.450.642.693'], ['F01.145.813']] | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Noscapine does not show aneugenic activity in mouse oocytes. | To clarify if noscapine has the ability to induce polyploidy in rodent germ cells in vivo, a cytogenetic study of mouse metaphase II oocytes was conducted after oral treatment with noscapine at the doses of 20, 120 and 400 mg/kg. Plasma concentrations of noscapine were measured by reversed-phase liquid chromatography a... | ['Aneuploidy', 'Animals', 'Female', 'Humans', 'Meiosis', 'Mice', 'Noscapine', 'Oocytes', 'Polyploidy', 'Species Specificity'] | 8,377,649 | [['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.144.220.220.687', 'G05.113.220.687'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.132.577.500', 'D03.633.100.531.567'], ['A05.360.490.690.680', 'A11.497.497.600'], ['C23.550.210.702', '... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolonged surveillance of dexfenfluramine in severe obesity. | Forty-two obese patients entered a placebo-controlled, double-blind 1-year study on dexfenfluramine, a serotonergic anorectic drug. Obesity was severe (mean body mass index 38.4 kg/m2), and of early onset and long duration. A mean of 8 attempts to lose weight was undertaken. After randomisation to 1 year of dexfenflura... | ['Adult', 'Body Weight', 'Double-Blind Method', 'Female', 'Fenfluramine', 'Follow-Up Studies', 'Humans', 'Male', 'Obesity, Morbid', 'Patient Dropouts'] | 8,107,932 | [['M01.060.116'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.092.471.683.467'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.45... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predictors and Outcomes of Nondiagnostic Ultrasound for Acute Appendicitis in Children. | Ultrasound assessments of children with possible acute appendicitis (AA) are often nondiagnostic. We aimed to identify the predictors of nondiagnostic ultrasound and to investigate the outcomes. A retrospective review was conducted on children aged 4 to 17 years evaluated in 2013 for AA with ultrasound at a tertiary ho... | ['Adolescent', 'Algorithms', 'Appendicitis', 'Biomarkers', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Predictive Value of Tests', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 29,336,754 | [['M01.060.057'], ['G17.035', 'L01.224.050'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.500.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Stochastic quasi-steady state approximations for asymptotic solutions of the chemical master equation. | In this paper, we propose two methods to carry out the quasi-steady state approximation in stochastic models of enzyme catalytic regulation, based on WKB asymptotics of the chemical master equation or of the corresponding partial differential equation for the generating function. The first of the methods we propose inv... | ['Algorithms', 'Catalysis', 'Computer Simulation', 'Enzyme Activation', 'Enzymes', 'Models, Chemical', 'Models, Molecular', 'Numerical Analysis, Computer-Assisted', 'Stochastic Processes'] | 24,832,255 | [['G17.035', 'L01.224.050'], ['G02.130'], ['L01.224.160'], ['G02.111.263', 'G03.328'], ['D08.811'], ['E05.599.495'], ['E05.599.595'], ['L01.224.680.700'], ['E05.318.740.996', 'G17.830', 'N05.715.360.750.770', 'N06.850.520.830.996']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Caspase inhibition impaired the neural stem/progenitor cell response after cortical ischemia in mice. | Cortical ischemia induces proliferation of neural stem/progenitor cells (NSPCs) in the subventricular zone (SVZ) and provokes migration of these cells toward the injured area. Despite sustained migration of NSPCs for an extended period of time after injury, they do not appear to survive. Here, we hypothesized that the ... | ['Amino Acid Chloromethyl Ketones', 'Animals', 'Caspase Inhibitors', 'Caspases', 'Cell Movement', 'Cell Proliferation', 'Cell Survival', 'Cerebral Cortex', 'Chemokine CCL2', 'Female', 'Hypoxia-Ischemia, Brain', 'Interleukin-1beta', 'Lateral Ventricles', 'Mice', 'Mice, Inbred C57BL', 'Neural Stem Cells', 'Neurogenesis',... | 26,734,998 | [['D12.125.065'], ['B01.050'], ['D27.505.519.389.745.325.500'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A08.186.211.200.885.287.500'], ['D12.644.276.374.200.110.99... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stage-specific signals in germ line differentiation: control of Sertoli cell phagocytic activity by spermatogenic cells. | Differentiation of male germ cells requires a continuous cross-talk with their somatic support, the Sertoli cell. An in vitro model of Sertoli cells was recently provided by established cell lines which maintain Sertoli-specific characteristics, among which is a regulated phagocytic capacity. In vivo, Sertoli cells tak... | ['Animals', 'Cell Communication', 'Cell Differentiation', 'Cell Line', 'Cells, Cultured', 'Cycloheximide', 'Fixatives', 'Formaldehyde', 'Male', 'Mice', 'Microspheres', 'Phagocytosis', 'Protein Synthesis Inhibitors', 'Sertoli Cells', 'Spermatozoa', 'Spleen'] | 9,142,992 | [['B01.050'], ['G04.085'], ['G04.152'], ['A11.251.210'], ['A11.251'], ['D03.383.621.808.240'], ['D27.720.355'], ['D02.047.407'], ['B01.050.150.900.649.313.992.635.505.500'], ['E07.565'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['D27.505.519.389.760'], ['A05.360.444.849.789', 'A11.382.952', 'A11.43... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Parkinson's disease and segmental coordination during turning: I. Standing turns. | OBJECTIVE: Many of the falls among people with Parkinson's disease (PD) occur during sudden, on-the-spot turning which requires systematic reorientation of axial segments towards the new direction. We examined whether a disturbance in the coordination of segmental reorientation is an important cause of turning difficul... | ['Adult', 'Aged', 'Ataxia', 'Biomechanical Phenomena', 'Female', 'Humans', 'Male', 'Middle Aged', 'Parkinson Disease', 'Psychomotor Performance'] | 23,786,733 | [['M01.060.116'], ['M01.060.116.100'], ['C10.597.350.090', 'C23.888.592.350.090'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['F02.808', 'G11.427.700', 'G11.561.660']] | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Forced expiratory flow-volume curves during the application of lower-body negative pressure. | Ten normal subjects were studied during supine rest and quiet standing, and when exposed, supine, to lower-body negative pressure (LBNP) of 30, 40 and 50 mmHg, each for a period of 7 min, in random order. Their partial and complete flow-volume curves, heart rate and blood pressure were recorded during the last 3 min in... | ['Adult', 'Decompression', 'Hemodynamics', 'Humans', 'Lower Body Negative Pressure', 'Male', 'Maximal Expiratory Flow-Volume Curves', 'Respiration', 'Vital Capacity'] | 3,828,550 | [['M01.060.116'], ['E02.278', 'G01.374.715.250'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.278.500'], ['E01.370.386.700.660.225.505', 'G09.772.650.300.630'], ['G09.772.705'], ['E01.370.386.700.485.750.900', 'G09.772.850.970']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The effect of endovascular laser therapy on the clinical course and on the mechanisms of antioxidant protection in bronchial asthma patients]. | Among new non-medicamentous treatment methods, endovascular blood radiation with helium-neon laser (HNL) merits attention. The method turned out highly effective, which made it possible to reduce the maintenance doses of glucocorticosteroids, to increase the times of remission, and to restore work fitness. HNL was foun... | ['Adult', 'Antioxidants', 'Asphyxia', 'Asthma', 'Combined Modality Therapy', 'Female', 'Humans', 'Laser Therapy', 'Lipid Peroxidation', 'Male', 'Middle Aged', 'Remission Induction'] | 1,523,565 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C23.550.260.095', 'C26.103'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['G02.111.515', 'G03.295.531.587'], ['M01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Irak-4 rs4251481 gene variant: as a risk factor on inflammatory bowel disease | Background/aim: Abnormal immune response occurs in individuals who have alleles associated with innate and adaptive immune
mechanisms that predispose to inflammatory bowel disease (IBD). Interleukin-1 receptor-associated kinase 4 (IRAK-4) involved in
the pathway produces cytokines that initiate and maintain inflammatio... | ['Adult', 'Alleles', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'Inflammatory Bowel Diseases', 'Interleukin-1 Receptor-Associated Kinases', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Real-Time Polymerase Chain Reaction', 'Risk Factors'] | 30,997,787 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.205.731', 'C06.405.469.432'], ['D08.811.913.696.620.682.700.526', 'D12.644.360.370', 'D12.776.476.384'], ['M01.060.116.630'], ['G05.365.795.598'], ['E05.393.620.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High-performance object tracking and fixation with an online neural estimator. | Vision-based target tracking and fixation to keep objects that move in three dimensions in view is important for many tasks in several fields including intelligent transportation systems and robotics. Much of the visual control literature has focused on the kinematics of visual control and ignored a number of significa... | ['Algorithms', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Neural Networks, Computer', 'Online Systems', 'Pattern Recognition, Automated', 'Photogrammetry'] | 17,278,573 | [['G17.035', 'L01.224.050'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['G17.485', 'L01.224.050.375.605'], ['L01.313.500.750.300.742'], ['L01.399.750'], ['E01.370.350.600.630']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Detection of mutants of the "a" determinant region of hepatitis B surface antigen S gene among Wuhan childhood patients]. | OBJECTIVE: To investigate whether the presence of HBV mutant in vaccinees simply reflects the prevalence of HBV mutant in a specific geographic area or is indeed due to the immune pressure induced by vaccination.METHODS: HBV S genes were amplified by using polymerase chain reaction (PCR) and DNA sequence analysis of th... | ['Child', 'China', 'Epitopes', 'Female', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Hepatitis B Vaccines', 'Hepatitis B virus', 'Humans', 'Male', 'Point Mutation', 'Vaccination'] | 16,092,983 | [['M01.060.406'], ['Z01.252.474.164'], ['D23.050.550'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D23.050.327.495.500.475'], ['D20.215.894.899.955.400'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.675'], ['... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A novel cell-permeable cromoglycate derivative inhibits type I Fc epsilon receptor mediated Ca2+ influx and mediator secretion in rat mucosal mast cells. | Type I Fc epsilon receptor (Fc epsilon RI) mediated Ca2+ uptake and secretion of rat serosal mast cells have been shown to be inhibited by disodium 1,3-bis [(2'-carboxylatochromon-5'-yl) oxy]-2-hydroxypropane (disodium cromoglycate, DSCG), which is widely employed in the treatment of allergic asthma [Foreman et al. (19... | ['Animals', 'Antigens, Differentiation, B-Lymphocyte', 'Biological Transport', 'Calcium', 'Cell Line', 'Cells, Cultured', 'Cromolyn Sodium', 'Histamine Release', 'Hydrolysis', 'Immunoglobulin E', 'Indicators and Reagents', 'Kinetics', 'Mast Cells', 'Mucous Membrane', 'Phosphorylation', 'Rats', 'Receptors, Fc', 'Recepto... | 1,704,255 | [['B01.050'], ['D23.050.301.264.051', 'D23.101.100.150'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['A11.251'], ['D03.383.663.283.266.300', 'D03.633.100.150.266.300'], ['G12.350'], ['G02.380'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.37... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serotonin in the brain of the goldfish, Carassius auratus. An immunocytochemical study. | The distribution of immunoreactive serotonin (5-HT) was investigated in the brain and pituitary gland of the goldfish with the use of indirect immunofluorescence technique. Immunoreactive cerebrospinal fluid-contacting neurons were found in the nucleus recessus lateralis and in the nucleus recessus posterioris of the h... | ['Animals', 'Brain Chemistry', 'Cyprinidae', 'Diencephalon', 'Female', 'Fluorescent Antibody Technique', 'Goldfish', 'Histocytochemistry', 'Male', 'Medulla Oblongata', 'Mesencephalon', 'Serotonin', 'Telencephalon'] | 6,357,477 | [['B01.050'], ['G02.111.150', 'G03.185'], ['B01.050.150.900.493.200.244'], ['A08.186.211.200.317'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.493.200.244.248.480'], ['E01.370.225.500.607', 'E01.370.225.750.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Role of the endocrine glands in divergence of plastic processes and energy metabolism in rats after extended exposure to hypergravity: cytologic investigation]. | Cytologic and morphometric investigations of the hypothesis, thyroid, thyroid and pancreas of rats after 19-d centrifugation at 2G revealed suppression of somatotropic hormone production by hypophyseal somatotrophs and insulin by pancreatic beta-cells, and intensification of thyrotrophic hormone production by hypophyse... | ['Animals', 'Energy Metabolism', 'Hypergravity', 'Insulin', 'Insulin Secretion', 'Insulin-Secreting Cells', 'Male', 'Pancreas', 'Pituitary Gland', 'Prognosis', 'Rats', 'Rats, Wistar', 'Somatotrophs', 'Thyroid Gland', 'Thyrotrophs', 'Thyroxine'] | 17,193,966 | [['B01.050'], ['G03.295'], ['G01.060.350.369.300'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414.131', 'A06.300.414.087', 'A06.390.131', 'A11.382.625.092', 'A11.436.294.092'], ['A03.734'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A role for mesothelial cells in the genesis of idiopathic pulmonary fibrosis?]. | Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and lethal process of unknown etiology. The sub-pleural localization of fibrosis is a hallmark of early IPF but no link between the pleura and IPF has been established yet. We developed an experimental model of pleural fibrosis induced by adenovirus-mediated... | ['Adenoviridae', 'Animals', 'Epithelial Cells', 'Idiopathic Pulmonary Fibrosis', 'Models, Animal', 'Rats', 'Transforming Growth Factor beta1'] | 21,166,126 | [['B04.280.030'], ['B01.050'], ['A11.436'], ['C08.381.765.500'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.644.276.374.687.100', 'D12.644.276.954.775.100', 'D12.776.467.374.687.100', 'D12.776.467.942.775.100', 'D23.529.374.687.100', 'D23.529.942.775.100']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Post-craniotomy analgesia: current practices in British neurosurgical centres--a survey of post-craniotomy analgesic practices. | BACKGROUND AND OBJECTIVE: An evaluation of post-craniotomy analgesia within the University Hospital of Wales Neurosurgical Unit, Cardiff, found that many patients were experiencing moderate to severe pain post-craniotomy. It was therefore decided to undertake a nationwide survey of analgesic practices in order to estab... | ['Analgesia', 'Analgesics', 'Benchmarking', 'Craniotomy', 'Health Care Surveys', 'Humans', 'Institutional Practice', 'Neurosurgery', 'Pain Measurement', 'Pain, Postoperative', 'Postoperative Care', 'Surgery Department, Hospital', 'Surveys and Questionnaires', 'United Kingdom'] | 15,918,378 | [['E03.091'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['E04.525.190'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Exploring parenthood in the New Zealand Heart Transplant Program. | Heart transplantation is an established treatment for end-stage cardiac disease. This study describes parenthood after heart transplantation in the New Zealand population. An analysis was performed of all heart recipients from the New Zealand program. Exclusion criteria were death within 3 months of transplantation or ... | ['Counseling', 'Family Characteristics', 'Female', 'Fertility', 'Health Care Surveys', 'Health Knowledge, Attitudes, Practice', 'Heart Transplantation', 'Humans', 'Live Birth', 'Male', 'Marital Status', 'New Zealand', 'Parents', 'Patient Education as Topic', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Rate', 'Pr... | 23,747,185 | [['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['G08.686.210'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['F01.1... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effects of exogenous oxytocin and progesterone on GnRH-induced short luteal phases in anoestrous ewes. | Two experiments investigate the effects of oxytocin and progesterone on premature luteolysis in ewes. In Expt 1, 20 anoestrous ewes were induced to ovulate by multiple injections of GnRH (250 ng i.v. every 2 h for 24 h) followed by a bolus injection of GnRH (125 micrograms, i.v.). Ten ewes received a continuous infusio... | ['Anestrus', 'Animals', 'Dinoprost', 'Female', 'Gonadotropin-Releasing Hormone', 'Luteal Phase', 'Oxytocin', 'Progesterone', 'Receptors, Oxytocin', 'Sheep', 'Uterus'] | 8,667,346 | [['G08.686.195.249'], ['B01.050'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['G08.686.605.410'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['D04.210.5... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of CO2 and low concentrations of O2 on fermentative metabolism of the ruminal ciliate Polyplastron multivesiculatum. | The effects of ruminal concentrations of CO2 and oxygen on the end products of endogenous metabolism and fermentation of D-glucose by the ruminal entodiniomorphid ciliate Polyplastron multivesiculatum were investigated. The principal metabolic products were butyric, acetic, and lactic acids, H2, and CO2. 13C nuclear ma... | ['Animals', 'Carbon Dioxide', 'Ciliophora', 'Cytochromes', 'Fermentation', 'Glucose', 'Hydrogen', 'Magnetic Resonance Spectroscopy', 'Oxygen', 'Rumen', 'Sheep'] | 1,906,698 | [['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.043.185'], ['D08.244', 'D12.776.422.220'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['D01.268.406', 'D01.362.340'], ['E05.196.867.519'], ['D01.268.185.550', 'D01.362.670'], ['A13.869.804'], ['B01.050.150.900.649.313.500.380.791']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Candida keroseneae sp. nov., a novel contaminant of aviation kerosene. | AIMS: To characterize and identify a novel contaminant of aviation fuel.METHODS AND RESULTS: Micro-organisms (yeasts and bacteria) were isolated from samples of aviation fuel. A yeast that proved to have been unrecorded previously was isolated from more than one fuel sample. This novel yeast proved to be a new species ... | ['Candida', 'DNA, Fungal', 'DNA, Ribosomal', 'DNA, Ribosomal Spacer', 'Kerosene', 'Molecular Sequence Data', 'Phylogeny', 'Species Specificity'] | 21,138,450 | [['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['D13.444.308.300'], ['D13.444.308.475'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['D20.345.630.600', 'N06.230.132.258.630.600'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G16.824']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Polyvictimization and risk for suicidal phenomena in a community sample of Spanish adolescents. | This study aims to provide data regarding the association between reported degree of victimization and suicidal phenomena, with special emphasis on gender differences. There were 923 adolescents recruited from eight secondary schools in Catalonia, Spain. The Youth Self-Report (YSR) and the Juvenile Victimization Questi... | ['Adolescent', 'Adolescent Behavior', 'Attitude to Health', 'Bullying', 'Crime Victims', 'Female', 'Humans', 'Juvenile Delinquency', 'Male', 'Peer Group', 'Secondary Prevention', 'Self Concept', 'Spain', 'Spouse Abuse', 'Suicidal Ideation'] | 24,364,131 | [['M01.060.057'], ['F01.145.022'], ['F01.100.150', 'N05.300.150'], ['F01.145.126.125.550', 'F01.145.813.213.500', 'I01.880.735.070'], ['M01.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.479'], ['F01.829.316.483'], ['E02.897', 'N02.421.726.825', 'N06.850.780.750'], ['F01.752.747.792'], ['Z01.542.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Specific identification of Plasmodium sporozoites using an indirect fluorescent antibody method. | The specific identification of plasmodial sporozoites is not possible on morphological grounds. This study presents a serological method for the identification of sporozoite species, indicating the suitability of this approach for detection and determination of sporozoites in wild vectors collected from malaria endemic... | ['Animals', 'Antibodies', 'Culicidae', 'Fluorescent Antibody Technique', 'Mice', 'Plasmodium', 'Plasmodium berghei', 'Rabbits'] | 6,137,889 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of psychosocial reserve capacity in anxiety and depression in patients with systemic lupus erythematosus. | AIM: To examine the relationship between reserve capacity measures and anxiety/depression among patients with systemic lupus erythematosus (SLE) from Southern California (SoCal), United States and Manila, Philippines.METHODS: A total of 235 participants with SLE completed self-reported scales to assess anxiety/depressi... | ['Adaptation, Psychological', 'Adult', 'Anxiety', 'California', 'Cognitive Reserve', 'Cross-Sectional Studies', 'Depression', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Optimism', 'Philippines', 'Prevalence', 'Protective Factors', 'Risk Factors', 'Self Concept', 'Self Report', 'Social ... | 28,261,991 | [['F01.058'], ['M01.060.116'], ['F01.470.132'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['F02.463.188.331'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['M01.060.116.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Influence of body mass index on outcome of pediatric chronic hepatitis C virus infection. | BACKGROUND AND AIMS: Evidence demonstrates that obesity is associated with progression of chronic hepatitis C virus (HCV) infection and poor response to interferon therapy among HCV-infected adults. However, this evidence has been confounded by multiple comorbidities present in adult cohorts and the use of single adult... | ['Adolescent', 'Antiviral Agents', 'Body Mass Index', 'Child', 'Disease Progression', 'Drug Resistance, Viral', 'Fatty Liver', 'Female', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Male', 'Models, Statistical', 'Multivariate Analysis', 'Obesity', 'Retrospective Studies'] | 20,531,022 | [['M01.060.057'], ['D27.505.954.122.388'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['C23.550.291.656'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['C06.552.241'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of PTEN inhibition on regulation of tau phosphorylation in an okadaic acid-induced neurodegeneration model. | One of pathological hallmarks of Alzheimer's disease (AD) is neurofibrillary tangles (NFTs) consisting of abnormally hyperphosphorylated tau. The molecular mechanisms underlying the regulation of tau hyperphosphorylation remain largely unclear. The phosphoinositide 3-kinase (PI3K)/Akt pathway has been implicated in the... | ['Cell Line, Tumor', 'Cell Survival', 'Enzyme Inhibitors', 'Gene Expression Regulation, Neoplastic', 'Glycogen Synthase Kinase 3', 'Humans', 'Membrane Proteins', 'Neuroblastoma', 'Okadaic Acid', 'PTEN Phosphohydrolase', 'Phosphorylation', 'RNA, Small Interfering', 'Signal Transduction', 'Time Factors', 'Transfection', ... | 22,906,543 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D27.505.519.389'], ['G05.308.370'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.500', 'D08.811.913.696.620.682.700.646.625', 'D12.644.360.300.500', 'D12.776.476.081.875', 'D12.776.476.300.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.5... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deficit of Motor Skill Acquisition on the Upper Limb Ipsilesional to the Injured Hemisphere in Individuals with Stroke. | BACKGROUND Movement deficits in limbs ipsilesional to the damaged hemisphere in individuals with stroke have been established through various motor tasks. Nevertheless, there has been little evidence regarding hindrance of motor skill acquisition on the ipsilesional limb in patients with stroke. Therefore, we attempted... | ['Aged', 'Brain Injuries', 'China', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Middle Aged', 'Motor Skills', 'Movement', 'Recovery of Function', 'Stroke', 'Stroke Rehabilitation', 'Upper Extremity'] | 31,283,752 | [['M01.060.116.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['Z01.252.474.164'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808.260'], ['G07.568', 'G11.427.410'], ['G16.757'], ['C10.228.140.300.775', 'C14.907.253.855'], ['E02.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Cutting-aspiration instruments. | Cutting-aspiration instruments are discussed in relation to design and principles of action. Experience with the Roto-extractor in over 100 cases is reviewed. Large pupillary openings were achieved in nearly all cases. No vitreous was attached to the wound postoperatively. Retinal detachment has not occurred to date in... | ['Adolescent', 'Adult', 'Cataract', 'Cataract Extraction', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Ophthalmologic Surgical Procedures', 'Postoperative Complications', 'Suction', 'Ultrasonic Therapy'] | 924,724 | [['M01.060.057'], ['M01.060.116'], ['C11.510.245'], ['E04.540.825.249'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E04.540'], ['C23.550.767'], ['E04.237.890'], ['E02.565.280.945']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunogenicity in rhesus of the Plasmodium vivax mosquito stage antigen Pvs25H with Alhydrogel and Montanide ISA 720. | Pvs25 is an ookinete surface protein from Plasmodium vivax that is the target of transmission-blocking antibodies. Two immunogenicity trials in rhesus monkeys with a recombinant form of the protein, Pvs25H, were undertaken. Monkeys were vaccinated with Pvs25H adsorbed to Alhydrogel or emulsified in Montanide ISA 720 at... | ['Adjuvants, Immunologic', 'Aluminum Hydroxide', 'Animals', 'Anopheles', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Antigens, Surface', 'Female', 'Humans', 'Macaca mulatta', 'Malaria Vaccines', 'Malaria, Vivax', 'Male', 'Mannitol', 'Oleic Acids', 'Plasmodium vivax', 'Random Allocation', 'Recombinant Proteins'] | 17,883,455 | [['D27.505.696.477.067'], ['D01.045.250.050', 'D01.056.037', 'D01.248.497.158.459.075'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['D23.050.301'], ['B01.050.150.900.649.313.988.40... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Production in large quantities of highly purified hydroxytyrosol from liquid-solid waste of two-phase olive oil processing or "Alperujo". | The effect of hydrothermal treatment of two-phase olive waste (alperujo) on the solubilization of hydroxytyrosol was studied. Different conditions of saturated steam were assayed. A high amount of hydroxytyrosol was solubilized and increased with increasing steaming temperature and time, reaching 1.4-1.7 g/100 g of dry... | ['Chromatography, High Pressure Liquid', 'Drug Stability', 'Food Handling', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Industrial Waste', 'Magnetic Resonance Spectroscopy', 'Olive Oil', 'Oxidation-Reduction', 'Phenylethyl Alcohol', 'Plant Oils', 'Solubility', 'Steam'] | 12,405,779 | [['E05.196.181.400.300'], ['E05.916.330'], ['J01.576.423.200'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.300'], ['D20.944.420', 'N06.850.460.710.420'], ['E05.196.867.519'], ['D10.212.302.380.580', 'D10.212.507.650', 'D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Use of the endostapler for the treatment of non-healing sinus secondary to a dehisced colorectal anastomosis. | BACKGROUND: A dehisced colorectal anastomosis complicated by a sinus, especially after preoperative radiation for colorectal cancer, may not heal. We describe our experience in the management of such a condition using the endoscopic surgical stapler.METHODS: Patients who underwent low anterior resection for rectal canc... | ['Aged', 'Anastomosis, Surgical', 'Colon', 'Colorectal Surgery', 'Female', 'Follow-Up Studies', 'Humans', 'Ileostomy', 'Male', 'Middle Aged', 'Postoperative Complications', 'Preoperative Care', 'Radiotherapy, Adjuvant', 'Rectal Neoplasms', 'Rectum', 'Retrospective Studies', 'Risk Assessment', 'Surgical Stapling', 'Surg... | 20,614,227 | [['M01.060.116.100'], ['E04.035'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['H02.403.810.208'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['M01.060.116.630'], ['C23.550.767']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
HIV infection among heroin users and area of residence. | The aim of this study was to develop a hypothesis to explain the link between HIV prevalence and area of residence. The study was conducted in two parts using two existing data sources. In Part 1, the bloodborne viral test status and test results of a sample of clients attending treatment in December 2001 in two areas ... | ['Adolescent', 'Adult', 'Bias', 'Cocaine-Related Disorders', 'Comorbidity', 'Demography', 'Female', 'HIV Infections', 'Hepatitis C', 'Heroin Dependence', 'Humans', 'Ireland', 'Male', 'Prevalence', 'Residence Characteristics'] | 17,120,604 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.150', 'N06.850.490.500'], ['C25.775.300', 'F03.900.300'], ['N05.715.350.225', 'N06.850.490.687'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA. | MHC class II (MHC-II) genes are regulated by an enhanceosome complex containing two gene-specific transcription factors, regulatory factor X complex (RFX) and CIITA. These factors assemble on a strictly conserved regulatory module (S-X-X2-Y) found immediately upstream of the promoters of all classical and nonclassical ... | ['Acetylation', 'Acetyltransferases', 'Antigens, Differentiation, B-Lymphocyte', 'Base Sequence', 'Cell Line, Tumor', 'Computational Biology', 'Conserved Sequence', 'DNA-Binding Proteins', 'Enhancer Elements, Genetic', 'Gene Expression Profiling', 'Genes, MHC Class II', 'Genetic Markers', 'Histocompatibility Antigens C... | 15,528,357 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D08.811.913.050.134'], ['D23.050.301.264.051', 'D23.101.100.150'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.190', 'A11.251.860.180'], ['H01.158.273.180', 'L01.313.124'], ['G02.111.570.580'], ['D12.776.260'], ['G02.111.570.080.689.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Anomalous left main coronary artery arising from the pulmonary artery in an adult: treatment by direct reimplantation. | We herein report the case of a 37-year-old woman in whom an anomalous origin of the left coronary artery from the pulmonary artery was surgically corrected. A magnetic resonance angiogram showed the left main coronary artery connecting to the right posterior portion of the pulmonary trunk, and exercise-stressed thalliu... | ['Adult', 'Aorta, Thoracic', 'Coronary Angiography', 'Coronary Vessel Anomalies', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Pulmonary Artery', 'Replantation'] | 8,782,308 | [['M01.060.116'], ['A07.015.114.056.372'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.240.400.210', 'C14.280.400.210', 'C16.131.240.400.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A07.015.114.715'], ['E04.936.494']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunogenicity Assessment of Lipegfilgrastim in Patients with Breast Cancer Receiving Chemotherapy. | Lipegfilgrastim is a long-acting, once-per-cycle, glycopegylated recombinant granulocyte colony-stimulating factor (G-CSF) used to prevent neutropenia in patients receiving myelosuppressive chemotherapy. This integrated analysis examined the immunogenicity of lipegfilgrastim and its potential clinical impact in two dou... | ['Adult', 'Aged', 'Antibodies, Neutralizing', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Clinical Trials, Phase II as Topic', 'Clinical Trials, Phase III as Topic', 'Female', 'Filgrastim', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Isoantibodies', 'Middle Aged', 'Neoplasm Staging', ... | 27,419,145 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.250.250.210', 'N05.715.360.330.250.250.210', 'N06.850.520.450.250.250.210'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Can women's childbearing and contraceptive intentions predict contraceptive demand? Findings from a longitudinal study in Central India. | CONTEXT: To predict the need for contraceptive services, family planning program managers often rely on levels of unmet need derived from measures of childbearing intentions. However, women's intention to use a method has not received as much attention as a measure of contraceptive demand.METHODS: A survey was conducte... | ['Adolescent', 'Adult', 'Age Factors', 'Community Health Planning', 'Contraception', 'Contraception Behavior', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Services Needs and Demand', 'Health Surveys', 'Humans', 'India', 'Intention', 'Middle Aged', 'Odds Ratio', 'Parity', 'Pregnancy', 'Regression Analysis... | 12,709,309 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['N03.349.650.185'], ['E02.875.194'], ['F01.145.688.500', 'G08.686.784.891.500'], ['F01.100.150.500', 'N05.300.150.410'], ['N03.349.380.420', 'N05.300.450'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.05... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adolescent externalizing behaviour, psychological control, and peer rejection: Transactional links and dopaminergic moderation. | This study investigated (1) reciprocal links among parental psychological control, peer rejection, and adolescent externalizing (aggressive and rule-breaking behaviour), and (2) the moderating effect of an adolescent genetic factor (biologically informed polygenic score for dopamine signalling). Three-year longitudinal... | ['Adolescent', 'Adolescent Behavior', 'Aggression', 'Catechol O-Methyltransferase', 'Dopamine Plasma Membrane Transport Proteins', 'Female', 'Genotype', 'Humans', 'Interpersonal Relations', 'Male', 'Parent-Child Relations', 'Peer Group', 'Polymorphism, Single Nucleotide', 'Psychological Distance', 'Receptors, Dopamine ... | 28,338,224 | [['M01.060.057'], ['F01.145.022'], ['F01.145.126.125', 'F01.145.813.045'], ['D08.811.913.555.500.250'], ['D12.776.157.530.450.625.124', 'D12.776.157.530.562.374.500.500', 'D12.776.157.530.937.500', 'D12.776.543.585.450.625.124', 'D12.776.543.585.562.374.500.500', 'D12.776.543.585.937.500'], ['G05.380'], ['B01.050.150.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical profile of hypertrophic cardiomyopathy identified de novo in rural communities. | OBJECTIVES: The purpose of this study was to assess the extent to which hypertrophic cardiomyopathy (HCM) exists unsuspected and undetected in the general population.BACKGROUND: Hypertrophic cardiomyopathy is a disease with diverse natural history for which the potential to produce adverse consequences has been emphasi... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cardiomyopathy, Hypertrophic', 'Death, Sudden, Cardiac', 'Echocardiography', 'Female', 'Health Surveys', 'Humans', 'Hypertrophy, Left Ventricular', 'Male', 'Middle Aged', 'Minnesota', 'Primary Health Care', 'Prospective Studies', 'Risk Assessment', 'Rural Population... | 10,334,429 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Muscarinic and beta-adrenergic receptor expression in peripheral lung from normal and asthmatic patients. | We used human peripheral lung from 8 mildly asthmatic patients and 11 normal donors to study the expression of muscarinic and beta-adrenergic receptors in asthma. There was no significant difference in the affinity or the density of muscarinic (labeled with [N-methyl-3H]scopolamine) and beta 1- and beta 2-adrenergic re... | ['Adult', 'Asthma', 'Blotting, Northern', 'Electric Stimulation', 'Female', 'Humans', 'Lung', 'Male', 'Parasympathetic Nervous System', 'RNA, Messenger', 'Radioligand Assay', 'Receptors, Adrenergic, beta', 'Receptors, Muscarinic', 'Reference Values', 'Trachea'] | 8,764,219 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.723.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['A08.800.050.600'], ['D13.444.735.544'], ['E01.370.225.985', 'E01.370.374.650', 'E01.370.384.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Our experience with surgery of chronic obstructive lesions of the subclavian artery. Apropos of 94 procedures. Critical analysis of our results]. | Patient characteristics, types of lesion, routes of approach and techniques employed are discussed in relation to 94 cases of surgical treatment for chronic obstruction of the subclavian artery. The most frequently (60% of cases) used procedure was an extrathoracic by-pass operation, thrombo-endarterectomy being perfor... | ['Adult', 'Aged', 'Aorta', 'Arterial Occlusive Diseases', 'Axillary Artery', 'Endarterectomy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Subclavian Artery', 'Thrombosis', 'Vertebral Artery'] | 6,631,258 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.056'], ['C14.907.137'], ['A07.015.114.085'], ['E04.100.814.456'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['A07.015.114.839'], ['C14.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Use of glucocorticoid hormones in multiple sclerosis]. | A long-term observation over patients with disseminated scleosis who were treated by glucorticoid hormones demonstrated that hormone therapy with short sessions and a standard scheme appeared to be uneffective. The presentation is based on an examination of 25 patients who had undergone a durative course of hormone the... | ['Acute Disease', 'Adolescent', 'Adult', 'Chronic Disease', 'Female', 'Glucocorticoids', 'Humans', 'Male', 'Multiple Sclerosis', 'Prednisolone', 'Remission, Spontaneous'] | 1,015,135 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['C23.550.291.500'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['D04.210.500.745.432.769.795'], ['C23.550.291.656.700', 'G16.767']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Behavioral effects of salsolinol and ethanol on mice selected for sensitivity to alcohol-induced sleep time. | Two lines of mice, selected for differential sensitivity to alcohol, were tested following intracisternal administration of salsolinol, a compound putatively formed following ethanol ingestion. Both lines showed dose-dependent decreases in activity following salsolinol. When injected with ethanol, alcohol-insensitive s... | ['Acetaldehyde', 'Animals', 'Behavior, Animal', 'Dose-Response Relationship, Drug', 'Ethanol', 'Female', 'Genetics, Behavioral', 'Genotype', 'Isoquinolines', 'Male', 'Mice', 'Motor Activity', 'Sleep', 'Time Factors'] | 913,242 | [['D02.047.064'], ['B01.050'], ['F01.145.113'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['F04.096.276', 'H01.158.273.343.290'], ['G05.380'], ['D03.633.100.531'], ['B01.050.150.900.649.313.992.635.505.500'], ['F01.145.632', 'G11.427.410.698'], ['F02.830.855', 'G11.561.803'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
An abnormality of oestrogen feedback in amenorrhoea-galactorrhoea. | Fourteen patients with amenorrhoea and hyperprolactin-anemia but no evidence of pituitary tumours were each given an intramuscular injection of 1 mg oestradiol benzoate. Thirteen patients failed to release luteinizing hormone in response to the oestrogen. This hypothalamic abnormality may help to explain the menstrual ... | ['Amenorrhea', 'Estradiol', 'Estrogens', 'Feedback', 'Female', 'Follicle Stimulating Hormone', 'Galactorrhea', 'Humans', 'Lactation Disorders', 'Luteinizing Hormone', 'Pregnancy', 'Progesterone', 'Prolactin', 'Secretory Rate'] | 1,170,923 | [['C23.550.568.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D27.505.696.399.472.277'], ['L01.906.394.211'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['C13.703.844.506.389', 'C17.800.090.937.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C1... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Insensitivity to the alpha2-adrenergic receptor blocker yohimbine hydrochloride and occurrence of spontaneous platelet macroaggregation (SPMA) in diabetes. | We report here a study of platelet aggregation in diabetes, induced by epinephrine and its inhibition by yohimbine hydrochloride (YH), an alpha(2)-adrenergic receptor-blocking agent. Interestingly, emergence of spontaneous platelet macroaggregation (SPMA) was observed in six out of 75 cases in the absence of any agonis... | ['Adrenergic alpha-2 Receptor Agonists', 'Adrenergic alpha-2 Receptor Antagonists', 'Adrenergic alpha-Agonists', 'Adrenergic alpha-Antagonists', 'Cells, Cultured', 'Diabetes Mellitus', 'Drug Antagonism', 'Drug Resistance', 'Epinephrine', 'Female', 'Humans', 'Male', 'Platelet Aggregation', 'Yohimbine'] | 15,823,867 | [['D27.505.519.625.050.100.100.200', 'D27.505.696.577.050.100.100.200'], ['D27.505.519.625.050.200.100.200', 'D27.505.696.577.050.200.100.200'], ['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['A11.251'], ['C18.452.394.750', 'C19.246'], ['... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Salegentibacter catena sp. nov., isolated from sediment of the South China Sea, and emended description of the genus Salegentibacter. | A novel marine bacterial strain, HY1T, was isolated from sediment of the South China Sea. The strain was aerobic and heterotrophic and formed saffron yellow-pigmented colonies on marine agar 2216. Cells were non-motile, Gram-negative rods, frequently occurring in chains. BLASTN searches revealed that the 16S rRNA gene ... | ['Aerobiosis', 'Bacterial Typing Techniques', 'Base Composition', 'Base Sequence', 'China', 'DNA, Bacterial', 'DNA, Ribosomal', 'Fatty Acids', 'Flavobacteriaceae', 'Genes, rRNA', 'Geologic Sediments', 'Locomotion', 'Molecular Sequence Data', 'Phylogeny', 'Pigments, Biological', 'Quinones', 'RNA, Bacterial', 'RNA, Ribos... | 17,267,953 | [['G02.111.017', 'G03.049'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.474.164'], ['D13.444.308.212'], ['D13.444.308.475'], ['D10.251'], ['B03.440.080.190', 'B03.440.400.425.310'], ['G05.360.340.024.340.645.750'], ['G01.311.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
X-ray diffraction and electron microscopy studies of frozen erythrocyte membrane preparations. | Well-defined X-ray diffraction patterns have been recorded from erythrocyte membranes in the frozen state. At -40 degrees C, lamellar periodicities range from 19 to 95 nm depending on the glycerol content (0--40%, respectively). Freeze-fracture electon micrographs of samples frozen in two stages to approximate to the d... | ['Differential Thermal Analysis', 'Dose-Response Relationship, Drug', 'Erythrocyte Membrane', 'Erythrocytes', 'Freeze Fracturing', 'Freezing', 'Glycerol', 'Humans', 'Microscopy, Electron', 'Temperature', 'X-Ray Diffraction'] | 7,397,175 | [['E05.196.370'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.225.500.620.620.260', 'E01.370.225.750.600.620.260', 'E05.200.500.620.620.260', 'E05.200.750.600.620.260'], ['G01.645.500', 'G01.906.595.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Health care relief to neighbors: Split University Hospital during the 1991-1995 war in Bosnia and Herzegovina. | AIM: To assess the workload of the Split University Hospital during the war and its role in providing help to the neighboring countries.METHODS: We reviewed all available records of patients admitted to the four (out of 15) departments: General Surgery, Traumatology, Dermatovenerology, and Pulmonology. The files of 37,... | ['Bosnia and Herzegovina', 'Croatia', 'Delivery of Health Care', 'Female', 'Hospitalization', 'Hospitals, University', 'Humans', 'International Cooperation', 'Male', 'Retrospective Studies', 'Warfare', 'Workload', 'Wounds and Injuries'] | 11,885,052 | [['Z01.542.248.160'], ['Z01.542.248.295'], ['N04.590.374', 'N05.300'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.... | ['Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Soluble interleukin-2 receptors in recurrent miscarriage and the effect of leukocyte immunotherapy. | The relationship between soluble interleukin-2 receptors (IL-2R) and pregnancy outcome was investigated in women with a history of miscarriage, some of whom were treated with partner-specific leukocyte immunotherapy. IL-2R were significantly elevated in patients with a poor obstetric history possessing cardiolipin anti... | ['Abortion, Habitual', 'Antibodies, Anticardiolipin', 'Female', 'Humans', 'Immunotherapy', 'Leukocytes', 'Placebos', 'Pregnancy', 'Pregnancy Outcome', 'Receptors, Interleukin-2', 'Recurrence', 'Solubility'] | 1,487,306 | [['C13.703.039.089'], ['D12.776.124.486.485.114.323.210.100', 'D12.776.124.790.651.114.323.210.100', 'D12.776.377.715.548.114.323.210.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['D26.660', 'E02.785'], ['G08.686.784.769'], ['E01.789.700... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chordoma-derived cell line U-CH1-N recapitulates the biological properties of notochordal nucleus pulposus cells. | Intervertebral disc degeneration proceeds with age and is one of the major causes of lumbar pain and degenerative lumbar spine diseases. However, studies in the field of intervertebral disc biology have been hampered by the lack of reliable cell lines that can be used for in vitro assays. In this study, we show that a ... | ['Biomarkers', 'CD24 Antigen', 'Cell Line, Tumor', 'Chondrogenesis', 'Chordoma', 'Female', 'Fetal Proteins', 'HEK293 Cells', 'Humans', 'Lumbar Vertebrae', 'Mesenchymal Stem Cells', 'Nucleus Pulposus', 'Pregnancy', 'Spinal Neoplasms', 'T-Box Domain Proteins'] | 27,248,133 | [['D23.101'], ['D12.776.395.550.200.098', 'D12.776.395.550.448.120', 'D12.776.543.484.500.120', 'D12.776.543.550.200.124', 'D12.776.543.550.418.120', 'D23.050.285.018', 'D23.050.301.350.098'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['C04.557.465.220'], ['D12.776.320'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A case study of simultaneous recovery from multiple physical symptoms with medical qigong therapy. | BACKGROUND: It is well known that qigong practice is beneficial to human health, but it is less known, even in China, that qigong may also be an effective therapy to treat various diseases. This report documents the story of a 58-year-old Caucasian male patient with a series of chronic conditions, including high prosta... | ['Accidents, Traffic', 'Asthma', 'Breathing Exercises', 'Edema', 'Heart Septal Defects, Atrial', 'Humans', 'Hypersensitivity', 'Hypertension', 'Leg', 'Male', 'Mental Healing', 'Middle Aged', 'Multiple Trauma', 'Prostate-Specific Antigen', 'Time Factors', 'Treatment Outcome'] | 15,025,889 | [['N06.850.135.392'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E02.190.525.186', 'E02.779.474.124'], ['C23.888.277'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['C14.907.489'], ['A01.378.610... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Influence of functional status of ovaries on results of controlled ovarian hyperstimulation]. | UNLABELLED: The controlled ovarian hyperstimulation is an integral part of infertility treatment. Its main objective is to obtain oocytes with a highest developmental potential. The stimulation protocols involving the gonadotropin-releasing hormone analogues and gonadotropins are considered as the most efficient. Despi... | ['Adult', 'Female', 'Humans', 'Infertility, Female', 'Ovary', 'Ovulation Induction', 'Retrospective Studies', 'Ultrasonography'] | 23,882,928 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['E02.875.800.984', 'E05.820.800.984'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sophorolipids improve sepsis survival: effects of dosing and derivatives. | INTRODUCTION: Sophorolipids, a family of natural and easily chemo-enzymatically modified microbial glycolipids, are promising modulators of the immune response. We have previously demonstrated that sophorolipids mediate anti-inflammatory effects, including decreasing sepsis-related mortality at 36 h in vivo in a rat mo... | ['Acetylation', 'Animals', 'Cecum', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Esters', 'Glycolipids', 'Injections, Intravenous', 'Ligation', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Sepsis', 'Survival Rate', 'Wounds, Stab'] | 17,719,064 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.241.400'], ['D09.400.410', 'D10.390'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E04.426'], ['B01.050.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monoaminergic inputs to frog motoneurons: an anatomical study using fluorescence histochemical and silver degeneration techniques. | The monoaminergic input to spinal segment 10 of the frog, Rana pipiens, was investigated anatomically. Fluorescence histochemistry demonstrated a diffuse and overlapping distribution of catecholamine (CA) and indoleamine (IA) containing terminals within the spinal cord. Terminal fields containing high numbers of CA and... | ['Animals', 'Anura', 'Brain Mapping', 'Catecholamines', 'Histocytochemistry', 'Male', 'Medulla Oblongata', 'Microscopy, Fluorescence', 'Motor Neurons', 'Neural Pathways', 'Rana pipiens', 'Spinal Cord', 'Tryptamines'] | 300,265 | [['B01.050'], ['B01.050.150.900.090.180'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. | Chemotherapeutic drugs chronically administered to tumor-bearing mice, using a frequent schedule at doses substantially lower than the maximum tolerated dose (MTD) (i.e., metronomic dosing), can cause sustained and potent antiangiogenic effects by targeting the endothelial cells of newly growing tumor blood vessels. Th... | ['Administration, Oral', 'Angiogenesis Inhibitors', 'Animals', 'Antineoplastic Agents', 'Cells, Cultured', 'Cyclophosphamide', 'Endothelium, Vascular', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, SCID', 'Microcirculation', 'Prostatic Neoplasms', 'Thrombospondin 1', 'Transplantation, Heterologous', ... | 14,561,896 | [['E02.319.267.100'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['D27.505.954.248'], ['A11.251'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of two membrane fusion proteins, synaptosome-associated protein of 25 kDa and vesicle-associated membrane protein, in choroid plexus epithelium. | In addition to being the major site of cerebrospinal fluid formation, the choroid plexus epithelium emerges as an important source of polypeptides in the brain. Physiologically regulated release of some polypeptides synthesized by the choroid plexus has been shown. The molecular mechanisms underlying this polypeptide s... | ['Animals', 'Blotting, Western', 'Choroid Plexus', 'Epithelium', 'Exocytosis', 'Immunohistochemistry', 'Male', 'Membrane Fusion', 'Membrane Proteins', 'Nerve Tissue Proteins', 'Precipitin Tests', 'R-SNARE Proteins', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sy... | 12,559,091 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211.140.298'], ['A10.272'], ['G04.468'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.20... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Tools for Rapid Genetic Engineering of Vibrio fischeri. | Vibrio fischeri is used as a model for a number of processes, including symbiosis, quorum sensing, bioluminescence, and biofilm formation. Many of these studies depend on generating deletion mutants and complementing them. Engineering such strains, however, is a time-consuming, multistep process that relies on cloning ... | ['Aliivibrio fischeri', 'Cellulose', 'Cloning, Molecular', 'DNA Nucleotidyltransferases', 'Gene Deletion', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Genetic Engineering', 'Mutagenesis, Insertional', 'Mutation', 'Promoter Regions, Genetic', 'Quorum Sensing', 'Symbiosis'] | 29,776,924 | [['B03.440.450.900.050.860', 'B03.660.250.830.050.860'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E05.393.220'], ['D08.811.913.696.445.308'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.36... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Synthesis and mesomorphic properties of rigid-core ionic liquid crystals. | Ionic liquid crystals combine the unique solvent properties of ionic liquids with self-organization found for liquid crystals. We report a detailed analysis of the structure-property relationship of a series of new imidazolium-based liquid crystals with an extended aromatic core. Investigated parameters include length ... | ['Crystallization', 'Ions', 'Liquid Crystals', 'Molecular Structure', 'Particle Size', 'Phase Transition', 'Stereoisomerism', 'Surface Properties', 'Temperature', 'X-Ray Diffraction'] | 17,949,091 | [['E05.196.300', 'G02.171'], ['D01.248.497'], ['J01.637.506'], ['G02.111.570', 'G02.466'], ['G02.712'], ['G01.645', 'G02.734'], ['G02.607.445.682'], ['G02.860'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['E05.196.309.742', 'E05.196.822.950', 'G01.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[The use of gas chromatographic profile of serum lipids for computer diagnosis]. | A procedure is described for studies of patterns of blood serum lipids using gas chromatographic apparatus with electronic detector and capillary quartz column containing the non-polar silicon phase under conditions of temperature gradient from 120 degrees to 280 degrees. The patterns obtained were interpreted by means... | ['Chromatography, Gas', 'Diagnosis, Computer-Assisted', 'Humans', 'Lipids'] | 3,057,740 | [['E05.196.181.349'], ['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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