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Modeling epidemics on adaptively evolving networks: A data-mining perspective. | The exploration of epidemic dynamics on dynamically evolving ("adaptive") networks poses nontrivial challenges to the modeler, such as the determination of a small number of informative statistics of the detailed network state (that is, a few "good observables") that usefully summarize the overall (macroscopic, systems... | ['Algorithms', 'Computer Simulation', 'Data Mining', 'Epidemics', 'Informatics', 'Models, Theoretical', 'Systems Analysis'] | 26,695,450 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['L01.313.500.750.280.199', 'L01.470.625'], ['N06.850.290.200'], ['L01.313'], ['E05.599'], ['L01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Prevalence of O157:H7 and non-O157 E. coli in Iranian domestic sheep. | The aim of the present study was the isolation of both E. coli O157 and non-O157 in sheep. Verotoxins (VT) 1, 2 and eae genes were tested for this propose. Sheep faces are an important source of Shiga toxin-producing Escherichia coli (STEC). Escherichia coli O157:H7 is a highly virulent food-borne pathogen and threat t... | ['Animals', 'Escherichia coli O157', 'Iran', 'Sheep, Domestic', 'Time Factors', 'Virulence Factors'] | 24,783,786 | [['B01.050'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150.180.100.800.250.500'], ['Z01.252.245.500.350'], ['B01.050.150.900.649.313.500.380.791.150'], ['G01.910.857'], ['D23.946.896']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Effect of oily vehicles on absorption of mepitiostane by the lymphatic system in rats. | [14C]Mepitiostane in various vehicles was administered to the small intestine of anaesthetized rats with cannulated thoracic ducts, and the effect of lipids on lymphatic absorption was examined. The extent of lymphatic absorption was greatest when administered in triolein and sesame oil, which are triglycerides of long... | ['Androstanols', 'Animals', 'Carbon Radioisotopes', 'Drug Carriers', 'Female', 'Intestinal Absorption', 'Intestine, Small', 'Lymph', 'Lymphatic System', 'Oils', 'Rats', 'Rats, Inbred Strains'] | 1,357,134 | [['D04.210.500.054.040'], ['B01.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D26.255.260', 'E02.319.300.380'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['A03.556.124.684'], ['A12.207.270.606', 'A15.382.520.150... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A survey of canine expressed sequence tags and a display of their annotations through a flexible web-based interface. | We have initially sequenced approximately 8,000 canine expressed sequence tags (ESTs) from several complementary DNA (cDNA) libraries: testes, whole brain, and Madin-Darby canine kidney (MDCK) cells. Analysis of these sequences shows that they provide partial sequence information for about 5%-10% of the canine genes. A... | ['Animals', 'Base Sequence', 'Databases, Genetic', 'Dogs', 'Expressed Sequence Tags', 'Molecular Sequence Data'] | 12,692,157 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['B01.050.150.900.649.313.750.250.216.200'], ['G05.360.340.024.340.137.275'], ['L01.453.245.667']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The diagnosis of dementia with single photon emission computed tomography. | Single photon emission computed tomography is a practical modality for the study of physiologic cerebral activity in vivo. We utilized single photon emission computed tomography and N-isopropyl-p-iodoamphetamine iodine 123 to evaluate regional cerebral blood flow in nine patients with Alzheimer's disease (AD), five hea... | ['Aged', 'Alzheimer Disease', 'Amphetamines', 'Brain', 'Cerebrovascular Circulation', 'Dementia', 'Female', 'Humans', 'Iodine Radioisotopes', 'Iofetamine', 'Male', 'Middle Aged', 'Parietal Lobe', 'Temporal Lobe', 'Tomography, Emission-Computed'] | 3,493,756 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D02.092.471.683.152'], ['A08.186.211'], ['G09.330.100.159'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D02.092.471.683.15... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A method for estimating three-dimensional human arm movement with two electromagnetic sensors. | Measurement of upper-limb movements is important in various domains. In this article, an upper-limb three-dimensional movement recording technique is proposed based on only two electromagnetic sensors. Two joints are considered with a total of seven degrees of freedom (DoF; three translations and four rotations). The c... | ['Adult', 'Arm', 'Biomechanical Phenomena', 'Calibration', 'Electromagnetic Phenomena', 'Humans', 'Joints', 'Male', 'Range of Motion, Articular'] | 21,153,971 | [['M01.060.116'], ['A01.378.800.075'], ['G01.154.090', 'G01.374.089'], ['E05.978.155'], ['G01.358.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583'], ['E01.370.600.700', 'G11.427.760']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence of cardiomegaly and left ventricular hypertrophy in scuba diving and traffic accident victims. | Although frequently asymptomatic, left ventricular hypertrophy (LVH) is an independent predictor of sudden cardiac death (SCD). We hypothesized that diving may increase the propensity for pre-existent LVH to cause a lethal arrhythmia (and SCD) and therefore the prevalence of LVH may be greater among scuba fatalities th... | ['Accidents, Traffic', 'Age Factors', 'Algorithms', 'Arrhythmias, Cardiac', 'Body Mass Index', 'Cardiomegaly', 'Case-Control Studies', 'Coronary Stenosis', 'Cross-Sectional Studies', 'Death, Sudden, Cardiac', 'Diving', 'Female', 'Humans', 'Hypertrophy, Left Ventricular', 'Linear Models', 'Male', 'Middle Aged', 'Organ S... | 24,851,550 | [['N06.850.135.392'], ['N05.715.350.075', 'N06.850.490.250'], ['G17.035', 'L01.224.050'], ['C14.280.067', 'C23.550.073'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14.280.195', 'C23.300.775.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Efficient retroviral transduction of human bone marrow progenitor and long-term culture-initiating cells: partial reconstitution of cells from patients with X-linked chronic granulomatous disease by gp91-phox expression. | The primary immunodeficiencies are attractive candidates for the development of gene therapy approaches based on the transduction of hematopoietic cells. We have constructed a high-titer recombinant retrovirus for expression of gp91-phox, deficiencies of which cause the X-linked form of chronic granulomatous disease (X... | ['Base Sequence', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Division', 'Cells, Cultured', 'Gene Transfer Techniques', 'Genetic Therapy', 'Genetic Vectors', 'Granulomatous Disease, Chronic', 'Hematopoietic Stem Cells', 'Humans', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'NADPH Oxidase 2', 'NADPH Oxid... | 8,611,697 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.148', 'A15.378.316'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['C15.378.553.774.535', 'C16.320.322.233', 'C20.673.774.535'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Is cold paresis related to axonal depolarization? | Cold paresis may occur in multifocal motor neuropathy and lower motor neuron disease. It was proposed to reflect nerve lesions where axons are depolarized due to loss of Na/K-pump activity. In those circumstances, a further decrease in pump activity by cooling may induce extra depolarization, conduction block, and weak... | ['Action Potentials', 'Adult', 'Axons', 'Cold Temperature', 'Electric Stimulation', 'Electromyography', 'Female', 'Humans', 'Male', 'Median Nerve', 'Muscle Contraction', 'Muscle, Skeletal', 'Neural Conduction', 'Paresis', 'Temperature', 'Young Adult'] | 21,040,145 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.723.402'], ['E01.370.405.255',... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Investigation of Clostridium botulinum group III's mobilome content. | Clostridium botulinum group III is mainly responsible for botulism in animals. It could lead to high animal mortality rates and, therefore, represents a major environmental and economic concern. Strains of this group harbor the botulinum toxin locus on an unstable bacteriophage. Since the release of the first complete ... | ['Animals', 'Botulinum Toxins', 'Botulism', 'Clostridium botulinum', 'Environmental Microbiology', 'Humans', 'Interspersed Repetitive Sequences'] | 29,287,670 | [['B01.050'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['C01.150.252.410.222.151', 'C10.668.758.200', 'C10.720.150', 'C25.723.415.151'], ['B03.300.390.400.200.160', 'B03.353.625.375.500.160', 'B03.510.415.400.200.160'], ['H01.158.273.540.274', 'N06.850.425'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Complementary molecular and elemental detection of speciated thioarsenicals using ESI-MS in combination with a xenon-based collision-cell ICP-MS with application to fortified NIST freeze-dried urine. | The simultaneous detection of arsenic and sulfur in thioarsenicals was achieved using xenon-based collision-cell inductively coupled plasma (ICP) mass spectrometry (MS) in combination with high-performance liquid chromatography. In an attempt to minimize the (16)O(16)O(+) interference at m/z 32, both sample introductio... | ['Arsenamide', 'Arsenic', 'Arsenicals', 'Chromatography, High Pressure Liquid', 'Freeze Drying', 'Mass Spectrometry', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrometry, Mass, Electrospray Ionization', 'Sulfur', 'Urine', 'Xenon'] | 18,157,667 | [['D02.129.040'], ['D01.268.513.249'], ['D01.075', 'D02.129'], ['E05.196.181.400.300'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E05.200.750.600.760.160.260', 'E05.760.156.260'], ['E05.196.566'], ['E05.318.370.725', 'E05.337.851', 'N05.715... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A microcomputer implementation of status and alarm algorithms in a cardiac surgical intensive care unit. | Algorithms have been developed for monitoring the cardiovascular status of patients on their return to an intensive care unit after cardiac surgery and also for giving an immediate alarm of a critical deterioration in this status. The two systems for implementing these algorithms were initially developed on Z80 based m... | ['Algorithms', 'Blood Pressure', 'Cardiac Surgical Procedures', 'Computer Graphics', 'Computers', 'Coronary Care Units', 'Heart Rate', 'Humans', 'Microcomputers', 'Monitoring, Physiologic', 'Postoperative Period', 'Signal Processing, Computer-Assisted', 'Software'] | 3,585,131 | [['G17.035', 'L01.224.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E04.100.376', 'E04.928.220'], ['L01.224.108', 'L01.296.110'], ['L01.224.230.260'], ['N02.278.388.493.211'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.260.550'], ['E01.370.520'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of viral and mycoplasma infections on ultrastructure and enzyme activities in human skeletal muscle. | The effect on skeletal muscle of acute viral and mycoplasma infections in thirteen men of ages ranging between 20-42 years has been studied. Comparisons are made with eight healthy men in the age group 22-29 years who were confined to bed for periods of time of lengths similar to the confinement to bed of the patients.... | ['Acute Disease', 'Adult', 'Citrate (si)-Synthase', 'Electron Transport Complex IV', 'Humans', 'L-Lactate Dehydrogenase', 'Male', 'Muscles', 'Muscular Diseases', 'Mycoplasma Infections', 'Oxo-Acid-Lyases', 'Thigh', 'Virus Diseases'] | 176,868 | [['C23.550.291.125'], ['M01.060.116'], ['D08.811.913.050.368'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.49... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiplex quantification of Escherichia coli, Salmonella typhi and Vibrio cholera with three DNA targets in single reaction assay. | Escherichia coli (E. coli), Salmonella typhi and Vibrio cholera harmful pathogens, which causes various diseases in humans. Rapid diagnosis of bacterial infection is an important for patient management and appropriate therapy during the early phase of the bacterial infected diseases. Among the existing techniques for i... | ['Bacterial Infections', 'Bacterial Proteins', 'Blood', 'DNA Primers', 'DNA, Bacterial', 'Escherichia coli', 'Female', 'Humans', 'Male', 'Molecular Diagnostic Techniques', 'Multiplex Polymerase Chain Reaction', 'Reproducibility of Results', 'Salmonella typhi', 'Sensitivity and Specificity', 'Urine', 'Vibrio cholerae'] | 28,606,647 | [['C01.150.252'], ['D12.776.097'], ['A12.207.152', 'A15.145'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.880', 'E05.200.880', 'E05.393.520'], ['E05.393.620.500.48... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The prevalence and health impact of shiftwork. | Data from the National Center for Health Statistics National Survey of Personal Health Practices and Consequences were analyzed to determine the impact of variable shift schedules on health-related behaviors of persons in the United States labor force. Twenty-six per cent of men and 18 per cent of women in the US labor... | ['Adult', 'Alcohol Drinking', 'Analysis of Variance', 'Circadian Rhythm', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Risk', 'Sex Factors', 'Sleep Wake Disorders', 'Stress, Psychological', 'Surveys and Questionnaires', 'Tranquilizing Agents', 'Work', 'Work Schedule Tolerance'] | 3,752,325 | [['M01.060.116'], ['F01.145.317.269'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['N05.715.350.675', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The role of tissue transglutaminase in the germinal vesicle breakdown of mouse oocytes. | We have investigated the novel function of tissue transglutaminase (tTG) in the germinal vesicle breakdown (GVBD) of mouse oocyte. tTG was identified in ooplasm and germinal vesicle by immunostaining with less amount in germinal vesicle. Spontaneous maturation of the oocytes elevated in situ activity of tTG by over 2.5... | ['Animals', 'Cadaverine', 'Cells, Cultured', 'Cystamine', 'Enzyme Inhibitors', 'GTP-Binding Proteins', 'Immunohistochemistry', 'Kinetics', 'Meiosis', 'Mice', 'Oocytes', 'Transglutaminases'] | 11,500,025 | [['B01.050'], ['D02.092.211.415.261', 'D02.092.782.258.174'], ['A11.251'], ['D02.092.471.200'], ['D27.505.519.389'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Should laparoscopic appendectomy be avoided for complicated appendicitis in children? | BACKGROUND/PURPOSE: Laparoscopic appendectomy is becoming the preferred technique for treating acute appendicitis. However, recent literature on adults suggests that laparoscopic appendectomy may increase the risk for postoperative infectious complications in complicated (gangrenous or perforated) cases. This study was... | ['Abdominal Abscess', 'Adolescent', 'Age Factors', 'Appendectomy', 'Appendicitis', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Patient Selection', 'Postoperative Complications', 'Retrospective Studies', 'Texas'] | 9,396,535 | [['C01.830.025.020'], ['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['E04.210.078'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E05.581.500.653', 'N04.590.731']... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Acute estrogen treatment facilitates recognition memory consolidation and alters monoamine levels in memory-related brain areas. | Acute effects of estrogens on mnemonic processes were examined at the behavioral and neurochemical levels. 17beta-estradiol and 17alpha-estradiol influences on memory consolidation were assessed using object placement (OP) and object recognition (OR) tasks. Subjects received treatment immediately after a sample trial (... | ['Animals', 'Biogenic Monoamines', 'Brain Chemistry', 'Estradiol', 'Estrogens', 'Female', 'Rats', 'Rats, Sprague-Dawley', 'Recognition, Psychology', 'Spatial Behavior'] | 20,553,724 | [['B01.050'], ['D02.092.211.215'], ['G02.111.150', 'G03.185'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['F02.463.425.540.706'], ['F01.145.875']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Curriculum Directors: influencing occupational therapy education, 1948-1964. | This paper depicts an important story in the history of occupational therapy. The story concerns a small group of women, known as the Curriculum Directors, whose influence prevailed in the growth and development of occupational therapy throughout the 1950s. The account is synthesized from both written history sources a... | ['Curriculum', 'History, 20th Century', 'Humans', 'Occupational Therapy', 'Societies', 'United States'] | 2,184,669 | [['I02.158'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['N03.540.828'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Evaluation of the clinical profile, laboratory parameters and outcome of two hundred COVID-19 patients from a tertiary centre in India. | COVID-19 is a pandemic with over 5 million cases worldwide. The disease has imposed a huge burden on health resources. Evaluation of clinical and epidemiological profiles of such patients can help in understanding and managing the outbreak more efficiently. This study was a prospective observational analysis of 200 dia... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Alanine Transaminase', 'Anemia', 'Aspartate Aminotransferases', 'Betacoronavirus', 'COVID-19', 'Child', 'Child, Preschool', 'Comorbidity', 'Coronary Artery Disease', 'Coronavirus Infections', 'Cough', 'Creatinine', 'Diabetes Mellitus', 'Female', 'Fever', 'Humans', '... | 33,169,598 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.913.477.700.100'], ['C15.378.071'], ['D08.811.913.477.700.225'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Variation in height and BMI of adult Indians. | It is well known that height and weight are interrelated, and that both are related to socioeconomic variables. The objective of this study was to assess the effect of socioeconomic variables on the heights and weights of different groups of people, formed according to different levels of heights and weights, and to se... | ['Adolescent', 'Adult', 'Age Factors', 'Body Height', 'Body Mass Index', 'Female', 'Health Surveys', 'Humans', 'India', 'Male', 'Middle Aged', 'Overweight', 'Sex Factors', 'Socioeconomic Factors', 'Thinness', 'Young Adult'] | 23,534,499 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.308.980.438', 'N05.715.360.300.800.438'... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pulsed in vitro release and in vivo behavior of exploding microcapsules. | Drug delivery systems which can generate multiple drug pulses after a single injection can be of major importance for e.g. the delivery of vaccines which often require multiple booster injections to generate sufficient immunity. In this paper, we report self-exploding microcapsules which can release their content in a ... | ['Animals', 'Biodegradation, Environmental', 'Capsules', 'Coated Materials, Biocompatible', 'Cross-Linking Reagents', 'Delayed-Action Preparations', 'Dextrans', 'Drug Carriers', 'Drug Delivery Systems', 'Emulsions', 'Female', 'Fluorescent Dyes', 'Gels', 'Green Fluorescent Proteins', 'Hydrogen-Ion Concentration', 'Indol... | 19,331,854 | [['B01.050'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D26.255.150'], ['D25.130.420', 'J01.637.051.130.420'], ['D27.720.470.410.210'], ['D26.255.210', 'E02.319.300.253'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['D20.280.260', 'D26.255.165.260'], ['D27.7... | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
E3 ubiquitin ligase E6AP negatively regulates adipogenesis by downregulating proadipogenic factor C/EBPalpha. | CCAAT/Enhancer Binding Protein Alpha (C/EBPá) is a key transcription factor involved in the adipocyte differentiation. Here for the first time we demonstrate that E6AP, an E3 ubiquitin ligase inhibits adipocyte differentiation in 3T3-L1 cells as revealed by reduced lipid staining with oil red. Knock down of E6AP in mou... | ['3T3-L1 Cells', 'Adipocytes', 'Adipogenesis', 'Animals', 'Biocatalysis', 'Bone Marrow Cells', 'CCAAT-Enhancer-Binding Protein-alpha', 'Cell Differentiation', 'Cell Separation', 'Down-Regulation', 'Gene Knockdown Techniques', 'Mesenchymal Stem Cells', 'Mice', 'Mice, Inbred C57BL', 'Models, Biological', 'Mutant Proteins... | 23,762,344 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['G04.152.149'], ['B01.050'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['A11.148', 'A15.378.316'], ['D12.776.260.108.124.500', 'D12.776.660.167.500', 'D12.776.930.127.124.500'], ['G04.152'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.3... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two new species of Willowsia (Collembola: Entomobryidae) from Guizhou Province, China. | The genus Willowsia Shoebotham, 1917 belongs to the family Entomobryidae. Within the family it is characterised by having 4-segmented antennae, 8+8 eyes, spines and scales absent from dens, claw with unpaired inner teeth, bidentate mucro and scales on body. Twenty-six species have been described in the genus worldwide ... | ['Animal Structures', 'Animals', 'Arthropods', 'Body Size', 'China', 'Color', 'Ecosystem', 'Female', 'Male', 'Organ Size'] | 27,615,876 | [['A13'], ['B01.050'], ['B01.050.500.131'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['Z01.252.474.164'], ['G01.590.540.199'], ['G16.500.275.157', 'N06.230.124'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Anemia of chronic renal failure in dogs. | Seventeen dogs with chronic renal failure (CRF) were studied to evaluate the incidence, type, and etiology of anemia in CRF. A nonregenerative, normochromic, normocytic anemia was seen in 12 of 17 dogs (70.6%). There was a direct correlation between the degree of anemia and the extent of CRF as assessed by serum creati... | ['2,3-Diphosphoglycerate', 'Analysis of Variance', 'Anemia', 'Animals', 'Blood Cell Count', 'Blood Chemical Analysis', 'Creatinine', 'Diphosphoglyceric Acids', 'Dog Diseases', 'Dogs', 'Erythrocytes', 'Erythropoietin', 'Female', 'Hematocrit', 'Kidney Failure, Chronic', 'Male', 'Osmotic Fragility', 'Parathyroid Hormone',... | 1,432,900 | [['D02.241.081.844.387.388.175', 'D02.241.511.902.387.388.175', 'D02.705.400.140.175', 'D09.811.366.388.175'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C15.378.071'], ['B01.050'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Angiographic cystoid macular edema after posterior chamber lens implantation. | We performed a prospective study evaluating the incidence of angiographic cystoid macular edema (CME) following extracapsular cataract extraction and posterior chamber intraocular lens implantation. Of the 162 eyes in the study, 141 were randomized into either a primary capsulotomy or a capsule intact group. The remain... | ['Aged', 'Cataract Extraction', 'Fluorescein Angiography', 'Humans', 'Lenses, Intraocular', 'Macular Edema', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Random Allocation'] | 3,369,996 | [['M01.060.116.100'], ['E04.540.825.249'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.500.460', 'E07.695.460'], ['C11.768.585.439.245'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Colorectal cancer screening adherence in a general population. | BACKGROUND: This article describes the self-reported colorectal cancer (CRC) screening adherence rates of adults, aged 50 years and older, living in five nonurban Minnesota counties.METHODS: During the year 2000, 1693 eligible respondents, aged 50 years and older, from a randomly selected sample completed a survey asse... | ['Aged', 'Barium', 'Colonoscopy', 'Colorectal Neoplasms', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Minnesota', 'Occult Blood', 'Patient Compliance', 'Sigmoidoscopy', 'Surveys and Questionnaires'] | 15,066,933 | [['M01.060.116.100'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Insulin-Like Growth Factor I Inhibits Alveolar Bone Loss Following Tooth Extraction in Rats. | BACKGROUND: Alveolar bone is often lost after tooth extraction. Few studies have assessed the longitudinal changes in bone volume that occur within these extraction sites.PURPOSE: To investigate the longitudinal morphological changes in extraction sockets following sustained continuous subcutaneous infusion of human re... | ['Alveolar Bone Loss', 'Animals', 'Humans', 'Insulin-Like Growth Factor I', 'Male', 'Mandible', 'Molar', 'Osteogenesis', 'Rats', 'Rats, Wistar', 'Tooth Extraction', 'Tooth Socket', 'X-Ray Microtomography'] | 24,852,941 | [['C05.116.264.150', 'C07.465.714.354.500'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['A14.549.167.860.525'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.5... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different roles for fibronectin in the generation of fore and hind limb precartilage condensations. | Fibronectin expression and spatiotemporal distribution were examined in relation to the distinctive patterns of mesenchymal condensation and chondrogenesis seen in high-density serum-free cultures of chicken wing and leg bud precartilage cells. More fibronectin protein was produced on a per cell basis by leg than by wi... | ['Animals', 'Cartilage', 'Cell Movement', 'Cells, Cultured', 'Chick Embryo', 'Fibronectins', 'Forelimb', 'Hindlimb', 'Mesoderm', 'RNA, Messenger', 'Transforming Growth Factor beta'] | 8,612,968 | [['B01.050'], ['A02.165', 'A10.165.382'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['A13.395'], ['A13.473'], ['A16.504.660'], ['D13.444.735.544'], ['D12.644.276.374.687', 'D12.644.276.954.77... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cost-utility analysis of antiviral use under pandemic influenza using a novel approach - linking pharmacology, epidemiology and heath economics. | Simulation models are used widely in pharmacology, epidemiology and health economics (HEs). However, there have been no attempts to incorporate models from these disciplines into a single integrated model. Accordingly, we explored this linkage to evaluate the epidemiological and economic impact of oseltamivir dose opti... | ['Adolescent', 'Adult', 'Aged', 'Antiviral Agents', 'Child', 'Child, Preschool', 'Cost-Benefit Analysis', 'Drug Costs', 'Female', 'Humans', 'Infant', 'Influenza, Human', 'Male', 'Middle Aged', 'Models, Economic', 'Models, Theoretical', 'Oseltamivir', 'Pandemics', 'Quality-Adjusted Life Years'] | 29,446,343 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.125'], ['N03.219.151.400.350', 'N05.300.375.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['M01.060.116.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Multicentric survey on hygienic aspects in private dental practice]. | The aim of this research was to evaluate the knowledge of cross-infection hazards in private dental practices, and their control procedures. The survey, carried out by questionnaire in 11 Italian cities, showed that dental personnel do not completely follow the main procedures for infection control. The interviewed sub... | ['Adult', 'Aged', 'Dentistry', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Infection Control', 'Italy', 'Male', 'Middle Aged', 'Private Practice'] | 14,969,326 | [['M01.060.116'], ['M01.060.116.100'], ['E06', 'H02.163'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.780.200.450'], ['Z01.542.489'], ['M01.060.116.630'], ['N04.452.758.745']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Sleep deprivation and accidental fall risk in children. | OBJECTIVES: To look for an association between sleep deprivation and risk of accidental falls (AF) in children.METHODS: A questionnaire was applied to two groups of children aged 1-14 years, encompassing children observed in an emergency room for AF (G1) and children attending health care visits (HV) (G2). Collected da... | ['Accidental Falls', 'Adolescent', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Emergency Service, Hospital', 'Female', 'Humans', 'Infant', 'Injury Severity Score', 'Logistic Models', 'Male', 'Risk Factors', 'Sleep Deprivation', 'Statistics, Nonparametric', 'Surveys and Questionnaires'] | 22,056,544 | [['N06.850.135.122'], ['M01.060.057'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.31... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Evaluation of transition zone biopsy in systematic prostate biopsy]. | We evaluated the systematic biopsies performed on 83 patients suspected of having prostate cancer. In the systematic biopsy, 6 cores were from the peripheral zone and 2 cores from the transition zone. Cancer was detected in 25 patients (30.1%). The percentage of patients who had abnormal digital rectal examination and ... | ['Aged', 'Aged, 80 and over', 'Biopsy', 'Humans', 'Male', 'Middle Aged', 'Prostate', 'Prostatic Neoplasms'] | 9,783,190 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A05.360.444.575', 'A10.336.707'], ['C04.588.945.440.770', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Secular trend in the occurrence of asthma among children and young adults: critical appraisal of repeated cross sectional surveys. | OBJECTIVES: To review repeated surveys of the rising prevalence of obstructive lung disease among children and young adults and determine whether systematic biases may explain the observed trends.DESIGN: Review of published reports of repeated cross sectional surveys of asthma and wheezing among children and young adul... | ['Adolescent', 'Adult', 'Asthma', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Data Collection', 'Global Health', 'Humans', 'Infant', 'Infant, Newborn', 'Prevalence', 'Respiratory Function Tests', 'Respiratory Sounds', 'Selection Bias'] | 9,224,081 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['H02.403.371', 'N01.400... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Tosyl-lysyl chloromethane alters glucocorticoid-receptor complex nuclear binding and physical properties. | We have investigated the effect of tosyl-lysyl chloromethane (a serine proteinase inhibitor) on rat liver cytosolic glucocorticoid-receptor complex binding to isolated nuclei. Tosyl-lysyl chloromethane (1-2 mM) significantly blocked nuclear binding when added before (but not after) thermal activation. Fifty percent inh... | ['Amino Acid Chloromethyl Ketones', 'Animals', 'Cell Nucleus', 'Centrifugation, Density Gradient', 'Cold Temperature', 'Cytosol', 'DEAE-Cellulose', 'Drug Stability', 'Hot Temperature', 'Liver', 'Male', 'Molybdenum', 'Protease Inhibitors', 'Proteins', 'Rats', 'Rats, Inbred Strains', 'Receptors, Glucocorticoid', 'Recepto... | 6,547,389 | [['D12.125.065'], ['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.181.724.336', 'E05.196.941.336'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Incidence, prevalence, and risk of eating disorder behaviors in military academy cadets. | Eating disorders are a particular problem for college students, as well as college athletes and military personnel. We examined the incidence, prevalence, and risk of eating disorders at the United States Military Academy (USMA) over a 7-year period (total population 12,731 cadets). The incidence per year for females w... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Incidence', 'Male', 'Military Personnel', 'New York', 'Prevalence', 'Psychology, Military', 'Psychometrics', 'Risk Factors', 'Stress, Psychological', 'Students', 'United States', 'Universities', 'Young Adult'] | 19,585,779 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.526.625'], ['Z01.107.567.875.075.437', 'Z01.107.567.875.350.530', 'Z01.107.567.875.500.530... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Fondaparinux therapy in a hemodialysis patient with heparin-induced thrombocytopenia type II. | PURPOSE: The successful use of fondaparinux in a hemodialysis patient with heparin-induced thrombocytopenia type II (HIT II) is reported.SUMMARY: An 85-year-old, 68-kg Caucasian woman came to the emergency department with shortness of breath and exertional chest pain radiating to the neck. Testing revealed non-ST-segme... | ['Aged, 80 and over', 'Anticoagulants', 'Arginine', 'Coronary Artery Bypass', 'Female', 'Fondaparinux', 'Heparin', 'Humans', 'Mitral Valve', 'Pipecolic Acids', 'Platelet Aggregation Inhibitors', 'Platelet Count', 'Polysaccharides', 'Renal Dialysis', 'Sulfonamides', 'Thrombocytopenia', 'Venous Thrombosis'] | 20,554,593 | [['M01.060.116.100.080'], ['D27.505.954.502.119'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['D09.698.629.429'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507'], ['D03.066.758', 'D03.383.62... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation and characterization of the outer membrane of Escherichia coli with autodisplayed Z-domains. | "Autodisplay technology" is an expression technique used to display the various recombinant proteins on the outer membrane (OM) of Escherichia coli. The resulting autodisplayed Z-domain has been used to improve the sensitivity of immunoassays. In this work, a facile isolation method of the OM fraction of E. coli with a... | ['Bacterial Outer Membrane Proteins', 'Blotting, Western', 'Cell Membrane', 'Escherichia coli', 'Escherichia coli Proteins', 'Lipid Bilayers', 'Models, Molecular', 'Multienzyme Complexes', 'NADH, NADPH Oxidoreductases', 'Protein Structure, Tertiary', 'beta-Galactosidase', 'beta-Lactamases'] | 25,528,472 | [['D12.776.097.120', 'D12.776.543.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.149'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D10.570.510', 'J01.637.087.500.510'], ['E05.599.595'], ['D05.500.562', 'D08.811.60... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Erythrocyte membrane skeletal protein bands 4.1 a and b are sequence-related phosphoproteins. | Bands 4.1 a and b are proteins of 80,000 and 78,000 molecular weight, which are both present at approximately 100,000 copies per erythrocyte ghost. Both proteins are components of the erythrocyte membrane skeleton. Bands 4.1 a and b are labeled when intact erythrocytes are incubated with [32P]orthophosphoric acid, and,... | ['Electrophoresis, Disc', 'Erythrocyte Membrane', 'Erythrocytes', 'Humans', 'Membrane Proteins', 'Molecular Weight', 'Peptide Fragments', 'Phosphoproteins', 'Spectrin'] | 7,068,651 | [['E05.196.401.402.236', 'E05.301.300.319.403'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['G02.494'], ['D12.644.541'], ['D12.776.744'], ['D12.776.220.980', 'D12.776.543.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete Genome Sequence of Germline Chromosomally Integrated Human Herpesvirus 6A and Analyses Integration Sites Define a New Human Endogenous Virus with Potential to Reactivate as an Emerging Infection. | Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated "CiHHV-6A/B". These affect approximately 1.0% of human populations, giving potential for virus gene expression in every cell. We previously showed that CiHHV-6A wa... | ['Base Sequence', 'Chromosomes, Human', 'Heart Failure', 'Herpesvirus 6, Human', 'Humans', 'Molecular Sequence Data', 'Phylogeny', 'Prospective Studies', 'Roseolovirus Infections', 'Virus Integration'] | 26,784,220 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['C14.280.434'], ['B04.280.382.150.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Survival and function of purified islets in the omental pouch site of outbred dogs. | The aims of this study were to devise an omental pouch site for islet implantation in a preclinical large animal and to compare the function of islets engrafted to this site with islets implanted into the spleen. Highly purified islets were isolated from outbred mongrel dogs, then grafted into totally pancreatectomized... | ['Animals', 'Dogs', 'Dose-Response Relationship, Drug', 'Female', 'Glucose', 'Hyperglycemia', 'Islets of Langerhans Transplantation', 'Male', 'Omentum', 'Spleen', 'Survival Rate', 'Transplantation, Autologous', 'Transplantation, Heterotopic', 'Transplantation, Homologous'] | 8,212,144 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.947.875.359.448'], ['C18.452.394.952'], ['E02.095.147.500.250', 'E04.270.550', 'E04.936.225.375'], ['A01.923.047.025.600.573'], ['A10.549.700', 'A15.382.520.604.700'], ['E05.318.308.985.550.900', 'N01.224.935.698.82... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of parental smoking on cotinine levels in newborns. | BACKGROUND: Smoking is a major risk factor for cot death. Many infants smoke passively as a result of parental smoking. This paper reports on infants exposed to a smoking environment and how they accumulate metabolites of cigarette smoke, such as cotinine, which may be physiologically harmful.AIM: To assess cotinine le... | ['Case-Control Studies', 'Cotinine', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Linear Models', 'Male', 'Multivariate Analysis', 'Parenting', 'Parents', 'Risk Factors', 'Smoking', 'Sudden Infant Death', 'Tobacco Smoke Pollution'] | 17,580,319 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D03.383.773.812.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control region. | Much of our understanding of the process by which enhancers activate transcription has been gained from transient-transfection studies in which the DNA is not assembled with histones and other chromatin proteins as it is in the cell nucleus. To study the activation of a mammalian gene in a natural chromatin context in ... | ['Animals', 'Cell Nucleus', 'Chromatin', 'DNA Replication', 'DNA-Binding Proteins', 'Erythroid-Specific DNA-Binding Factors', 'GATA1 Transcription Factor', 'Globins', 'Humans', 'Mammals', 'NF-E2 Transcription Factor', 'NF-E2 Transcription Factor, p45 Subunit', 'Nuclear Proteins', 'Nucleosomes', 'Promoter Regions, Genet... | 8,887,635 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['G02.111.225', 'G05.226'], ['D12.776.260'], ['D12.776.260.235', 'D12.776.930.216'], ['D12.776.260.235.500', 'D12.776.260.257.100', 'D12.776.930.216.500', 'D12.776.930.314.100... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Perventricular Implantation of Melody Valve in Child With Pulmonary Hypertension After a Potts Shunt. | The Potts operation is a surgical option for the treatment of children with suprasystemic pulmonary arterial hypertension (PAH). Its positive hemodynamic effect may be obliterated by pulmonary valvar insufficiency. We describe a case in which the Potts shunt was followed by perventricular Melody valve implantation in t... | ['Anastomosis, Surgical', 'Angiography', 'Child, Preschool', 'Echocardiography', 'Female', 'Heart Ventricles', 'Humans', 'Hypertension, Pulmonary', 'Postoperative Complications', 'Pulmonary Artery', 'Pulmonary Valve Insufficiency', 'Tomography, X-Ray Computed', 'Truncus Arteriosus', 'Vascular Surgical Procedures'] | 28,633,267 | [['E04.035'], ['E01.370.350.700.060', 'E01.370.370.050'], ['M01.060.406.448'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['C23.550.767'], ['A07.015.114.715'], ['C14.280.484.660'], ['E01.370... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of Trypanosoma cruzi from Argentina by electrophoretic zymograms. | Polyacrylamide gel electrophoretic patterns for six enzymes in 73 isolates and 38 clones of Trypanosoma cruzi from different areas of Argentina were classified into 12 zymodemes. The isolates were obtained from human patients with acute, chronic or congenital Chagas' disease, vector insects, domestic and sylvatic anima... | ['Animals', 'Animals, Domestic', 'Animals, Wild', 'Argentina', 'Carnivora', 'Chagas Disease', 'Dogs', 'Electrophoresis, Polyacrylamide Gel', 'Enzymes', 'Guinea Pigs', 'Humans', 'Insect Vectors', 'Mephitidae', 'Rodentia', 'Triatoma', 'Trypanosoma cruzi'] | 1,685,868 | [['B01.050'], ['B01.050.050.116'], ['B01.050.050.300'], ['Z01.107.757.077'], ['B01.050.150.900.649.313.750'], ['C01.610.752.300.900.200', 'C01.920.625'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.196.401.402', 'E05.301.300.319'], ['D08.811'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.4... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Factors determining pesticide use practices by farmers in the Sultanate of Oman. | In a study of pesticide use on farms in Oman, over 200 respondents were surveyed from amongst owners of and workers on farms that belonged to a Farmers' Association (FA) and those that did not belong to the FA. A questionnaire was used to gauge attitudes to pesticide use whilst inventories of active ingredients were ta... | ['Adult', 'Agriculture', 'Educational Status', 'Humans', 'Oman', 'Pesticides', 'Surveys and Questionnaires'] | 24,486,502 | [['M01.060.116'], ['J01.040'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.600'], ['D27.720.031.700', 'D27.888.723'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Low methionine ingestion by rats extends life span. | Dietary energy restriction has been a widely used means of experimentally extending mammalian life span. We report here that lifelong reduction in the concentration of a single dietary component, the essential amino acid L-methionine, from 0.86 to 0.17% of the diet results in a 30% longer life span of male Fischer 344 ... | ['Animals', 'Diet', 'Eating', 'Energy Intake', 'Longevity', 'Male', 'Methionine', 'Rats', 'Rats, Inbred F344', 'Weight Gain'] | 8,429,371 | [['B01.050'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.650.240.340'], ['G07.345.124.519', 'G07.540'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.200', 'B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A test of the frontal lobe functioning hypothesis of age deficits in production priming. | Older adults have been hypothesized to show reduced priming relative to younger adults on implicit memory tests that require production of a response because these tasks place high demands on attentional processes associated with frontal lobe function, which are often reduced with age (see D. A. Fleischman & J. D. E. G... | ['Adolescent', 'Adult', 'Aging', 'Attention', 'Cues', 'Female', 'Frontal Lobe', 'Humans', 'Male', 'Memory', 'Memory Disorders', 'Mental Recall', 'Neuropsychological Tests', 'Perception', 'Psychomotor Performance'] | 16,938,016 | [['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['F02.830.104.214'], ['F02.463.425.234'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['F02.463.425.540.641'], ['F04.711.513'], ['F02.463.593'], [... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of dietary fiber and fat on performance and digestive traits of broilers from one to twenty-one days of age. | The influence of fiber source and dietary fat level on digestive traits and productive performance was studied in broilers from 1 to 21 d of age. There were 6 treatments arranged factorially with 3 sources of fiber (none; 3% oat hulls, OH; and 3% sugar beet pulp, SBP) and 2 fat sources (5% soybean oil, SO; and 5% yello... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Chickens', 'Diet', 'Dietary Fats', 'Dietary Fiber', 'Digestion', 'Male'] | 19,903,955 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.250', 'G10.261.190']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Relationship between vitamin D deficiency and nondipper hypertension. | Nondipper hypertension is associated with increased cardiovascular morbidity and mortality. Vitamin D deficiency is associated with cardiovascular diseases such as coronary artery disease, heart failure, and hypertension. Vitamin D deficiency activates the renin-angiotensin-aldosterone system, which affects the cardiov... | ['Antihypertensive Agents', 'Blood Pressure', 'Calcifediol', 'Circadian Rhythm', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Parathyroid Hormone', 'Renin-Angiotensin System', 'Ultrasonography', 'Vitamin D Deficiency'] | 22,594,967 | [['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D04.210.500.247.222.159.478.250', 'D04.210.500.247.808.146.478.250', 'D04.210.500.812.768.196.478.250', 'D10.570.938.146.478.250'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['D06.47... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predictors of job strain in residential dementia care nursing staff. | AIM: To identify predictors of job strain in residential nursing care staff working with people with dementia.BACKGROUND: It is well known that nursing staff experience high levels of stress, but less is known about how to predict job strain.METHODS: The job strain of nursing care staff (n = 344) within residential dem... | ['Adaptation, Psychological', 'Adult', 'Aged, 80 and over', 'Dementia', 'Female', 'Humans', 'Job Satisfaction', 'Linear Models', 'Male', 'Models, Statistical', 'Multivariate Analysis', 'Nursing Staff', 'Occupational Health', 'Residential Facilities', 'Stress, Psychological', 'Surveys and Questionnaires'] | 19,166,523 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100.080'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.52... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes. | We previously reported that Na(+)/H(+) exchanger type 3 (NHE3) and NaPi2 are acutely retracted from the proximal tubule (PT) microvilli (MV) during acute hypertension [high blood pressure (BP)] or parathyroid hormone (PTH) treatment. By subcellular membrane fractionation, NHE3 and NaPi2 show indistinguishable redistrib... | ['Animals', 'Blotting, Western', 'Endosomes', 'Fluorescent Antibody Technique, Indirect', 'Hypertension, Renal', 'Kidney Cortex', 'Kidney Tubules, Proximal', 'Lysosomes', 'Male', 'Microscopy, Confocal', 'Microscopy, Immunoelectron', 'Microvilli', 'Parathyroid Hormone', 'Phosphates', 'Rats', 'Rats, Sprague-Dawley', 'Sod... | 15,265,767 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.430.214.190.875.190.880.337'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['C12.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Benefits of High Relaxivity for Brain Tumor Imaging: Results of a Multicenter Intraindividual Crossover Comparison of Gadobenate Dimeglumine with Gadoterate Meglumine (The BENEFIT Study). | BACKGROUND AND PURPOSE: Gadobenate dimeglumine (MultiHance) has higher r1 relaxivity than gadoterate meglumine (Dotarem) which may permit the use of lower doses for MR imaging applications. Our aim was to compare 0.1- and 0.05-mmol/kg body weight gadobenate with 0.1-mmol/kg body weight gadoterate for MR imaging assessm... | ['Adult', 'Aged', 'Brain Neoplasms', 'Contrast Media', 'Cross-Over Studies', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meglumine', 'Middle Aged', 'Organometallic Compounds'] | 26,185,325 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D27.505.259.500', 'D27.720.259'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['D02.033.800.813.550', 'D09.067.342.600'... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Aspirin, but Not Tirofiban Displays Protective Effects in Endotoxin Induced Lung Injury. | BACKGROUND: Treatment of acute lung injury (ALI) remains an unsolved problem in intensive care medicine. Recruitment of neutrophils into the lungs, regarded as a key mechanism in progression of ALI, depends on signaling between neutrophils and platelets. Consequently we explored the effect of platelet-targeted aspirin ... | ['Acute Lung Injury', 'Animals', 'Endotoxins', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neutrophils', 'Tirofiban', 'Tyrosine'] | 27,583,400 | [['C08.381.520.500'], ['B01.050'], ['D23.946.123.329'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D12.1... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuronal activity and its influence on developmentally regulated GABA(A) receptor expression in cultured mouse cerebellar granule cells. | Mouse cerebellar granule cells (CGCs) were cultured in either non-depolarising (5 mM KCl, '5K') or depolarising (25 mM KCl, '25K') media. CGCs at 5K developed an elaborate network of processes and formed compact cell aggregates, whilst at 25K, cell aggregation was rarely observed. GABA(A) receptor (GABAR) expression wa... | ['Animals', 'Cells, Cultured', 'Cerebellum', 'DNA Primers', 'DNA, Complementary', 'Electrophoresis, Polyacrylamide Gel', 'Electrophysiology', 'Kinetics', 'Mice', 'Neurons', 'RNA', 'Radioligand Assay', 'Receptors, Complement 3b', 'Receptors, GABA-A', 'Reverse Transcriptase Polymerase Chain Reaction'] | 12,367,617 | [['B01.050'], ['A11.251'], ['A08.186.211.132.810.428.200'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['E05.196.401.402', 'E05.301.300.319'], ['H01.158.344.528', 'H01.158.782.236'], ['G01.374.661', 'G02.111.490'], ['B01.050... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnostic Challenge in Pancreatic Sarcoidosis Using Endoscopic Ultrasonography. | We herein report a 55-year-old woman who presented with erythema and bilateral hilar lymphadenopathy 4 months prior to the detection of pancreatic lesions on an ultrasound. A skin biopsy showed evidence of sarcoidosis. The largest lesion in the tail of the pancreas was hypoechoic on endoscopic ultrasonography (EUS). Th... | ['Biopsy, Fine-Needle', 'Endosonography', 'Female', 'Humans', 'Middle Aged', 'Pancreas', 'Pancreatic Diseases', 'Sarcoidosis'] | 29,033,431 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.350.850.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A03.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[(18)F] FP-CIT PET study in parkinsonian patients with leukoaraiosis. | BACKGROUNDS: Leukoaraiosis may present with slowly progressive parkinsonism indistinguishable from primary degenerative parkinsonism. Both leukoaraiosis and degenerative parkinsonism are an age-related disorder. Thus, comorbidity is expected to be common in elderly patients with parkinsonism. However, no systematic stu... | ['Aged', 'Aged, 80 and over', 'Corpus Striatum', 'Female', 'Fluorine Radioisotopes', 'Humans', 'Leukoaraiosis', 'Male', 'Parkinsonian Disorders', 'Positron-Emission Tomography', 'Substantia Nigra'] | 25,937,616 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211.200.885.287.249.487'], ['D01.496.749.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.522'], ['C10.228.140.079.862', 'C10.228.662.600'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.825.80... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationship between body mass index and local quality of mandibular bone structure in elderly individuals. | BACKGROUND: Human bones decrease in density and increase in porosity beginning at about the third decade of life. The objective of this study was to determine whether mandibular bone mineral density (BMD) and some linear radiomorphometric measurements on dental panoramic radiograph (DPR) are correlated with different c... | ['Aged', 'Aged, 80 and over', 'Body Mass Index', 'Bone Density', 'Female', 'Humans', 'Male', 'Mandible', 'Middle Aged', 'Observer Variation', 'Radiography, Panoramic'] | 12,196,496 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenosine A2B receptor stimulates angiogenesis by inducing VEGF and eNOS in human microvascular endothelial cells. | Angiogenesis is critical to wound repair due to its role in providing oxygen and nutrients that are required to support the growth and function of reparative cells in damaged tissues. Adenosine receptors are claimed to be of paramount importance in driving wound angiogenesis by inducing VEGF. However, the underlying me... | ['Acetamides', 'Adenosine', 'Capillaries', 'Cell Line', 'Cyclic AMP', 'Dose-Response Relationship, Drug', 'Endothelial Cells', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Microcirculation', 'Neovascularization, Physiologic', 'Nitric Oxide Synthase Type III', 'Oxygen', 'Phosphatidylinositol 3-Kinases', 'Phosph... | 25,966,978 | [['D02.065.064', 'D02.241.081.018.110'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['A07.015.461.165'], ['A11.251.210'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436.275'], ['G05.308.320'], ['... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Paternal pericentric inversion of chromosome 4 as a cause of recurrent pregnancy loss. | A paternal pericentric inversion of chromosome 4 was ascertained through karyotype analysis of an abortus specimen proven to be 46,XX,rec(4),dup q, inv (4)(p13q28). The relationship of paternal pericentric inversion to pregnancy loss is discussed, and a recommendation for karyotype analysis of recurrent abortion specim... | ['Abortion, Habitual', 'Adult', 'Chromosome Inversion', 'Chromosomes, Human, Pair 4', 'Fathers', 'Female', 'Humans', 'Karyotyping', 'Male', 'Models, Genetic', 'Pregnancy'] | 8,182,725 | [['C13.703.039.089'], ['M01.060.116'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['A11.284.187.520.300.280.285', 'G05.360.162.520.300.280.285'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.3... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Low dose ionising radiation leads to a NF-êB dependent decreased secretion of active IL-1â by activated macrophages with a discontinuous dose-dependency. | PURPOSE: Therapy with low doses of ionising radiation (X-rays) exerts anti-inflammatory effects. Little is known about whether and how low doses of X-ray treatment modulate the inflammatory phenotype of macrophages, especially the secretion of Interleukin-1beta (IL-1â).MATERIALS AND METHODS: Macrophages were differenti... | ['Cell Line, Tumor', 'Dose-Response Relationship, Radiation', 'Humans', 'Inflammation', 'Interleukin-1beta', 'Macrophages', 'Transcription Factor RelA', 'X-Rays'] | 22,545,750 | [['A11.251.210.190', 'A11.251.860.180'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.37... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Efficient and chemoselective surface immobilization of proteins by using aniline-catalyzed oxime chemistry. | Site-specific immobilization of peptides and proteins is crucial to ensure their functionality in surface-based assays. We report the use of aniline-catalyzed oxime ligations as a very efficient and broadly applicable method to covalently attach the N terminus of proteins and peptides to a surface functionalized with a... | ['Aniline Compounds', 'Biosensing Techniques', 'Catalysis', 'Immobilized Proteins', 'Oximes', 'Peptides', 'Substrate Specificity'] | 19,241,407 | [['D02.092.146'], ['E05.601.043'], ['G02.130'], ['D12.776.463'], ['D02.092.570.665'], ['D12.644'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ATP-dependent chromatin remodeling and histone acetyltransferases in 5-FU cytotoxicity in Saccharomyces cerevisiae. | Chromatin is thought to modulate access of repair proteins to DNA lesions, and may be altered by chromatin remodelers to facilitate repair. We investigated the participation of chromatin remodelers and DNA repair in 5-fluorouracil (5-FU) cytotoxicity in Saccharomyces cerevisiae. 5-FU is an antineoplastic drug commonly ... | ['Adenosine Triphosphate', 'Cell Cycle Checkpoints', 'Chromatin Assembly and Disassembly', 'DNA Repair', 'DNA, Fungal', 'Dose-Response Relationship, Drug', 'Fluorouracil', 'Histone Acetyltransferases', 'Homologous Recombination', 'Microbial Sensitivity Tests', 'Mutation', 'Saccharomyces cerevisiae'] | 23,661,467 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G04.144.109'], ['G04.400.095', 'G05.213.095', 'G05.308.095'], ['G02.111.222', 'G05.219'], ['D13.444.308.300'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.383.742.698.875.404'], ['D08.811.913.050.134.415.500'], ['G05.728.615'], ['E01.37... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial consequences of defective processing of specific yeast mRNAs revealed by fluorescent in situ hybridization. | This work introduces the first use of fluorescent in situ hybridization (FISH) to detect the distribution of specific transcripts in Saccharomyces cerevisiae. We have applied this technique to analysis of reporter transcripts from a single, integrated copy, or multicopy plasmids. We have evaluated the effect of splice ... | ['Base Sequence', 'Consensus Sequence', 'Genes, Reporter', 'In Situ Hybridization, Fluorescence', 'Lac Operon', 'Molecular Sequence Data', 'Plasmids', 'RNA Polymerase II', 'RNA Precursors', 'RNA Processing, Post-Transcriptional', 'RNA, Fungal', 'RNA, Messenger', 'Saccharomyces cerevisiae', 'Sequence Deletion', 'Transcr... | 8,595,562 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580.175'], ['G05.360.340.024.340.435'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['G05.360.340.024.686.545', 'G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Insights from the First International Conference on Hyperacusis: causes, evaluation, diagnosis and treatment. | The First International Conference on Hyperacusis gathered over 100 scientists and health care professionals in London, UK. Key conclusions from the conference included: (1) Hyperacusis is characterized by reduced tolerance of sound that has perceptual, psychological and social dimensions; (2) there is a growing awaren... | ['Adult', 'Anxiety', 'Auditory Cortex', 'Auditory Perception', 'Child', 'Cognitive Behavioral Therapy', 'Humans', 'Hyperacusis', 'Noise', 'Sound'] | 24,804,717 | [['M01.060.116'], ['F01.470.132'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['F02.463.593.071', 'G07.888.125'], ['M01.060.406'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.458.505', 'C10.597.751.418.505', 'C23.888.592.763.393.505'], ['G01.750.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Psychological and possible psychiatric aspects of hyperthyroidism]. | Hyperthyroidism has always been the challenge for psychosomatic investigations. In traditional scientific literature the specific structure of hyperthyroid personality was pointed out. Severe and important emotional influences can induce disease in such, prone personalities. This investigation fails in featuring the sp... | ['Adult', 'Female', 'Humans', 'Hyperthyroidism', 'Male', 'Middle Aged', 'Psychological Tests', 'Psychophysiologic Disorders'] | 2,642,203 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['M01.060.116.630'], ['F04.711'], ['C23.888.592.700']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A quantitative study of water proton relaxation in packed beds of porous particles with varying water content. | A quantitative analysis of the dependence of water proton relaxation on water content in randomly packed beds of Sephadex is undertaken. A combination of Osmotic and Capillary theory is used to describe the morphological changes occurring in the packed beds as the water content is lowered. At each water content the wat... | ['Dextrans', 'Gels', 'Magnetic Resonance Spectroscopy', 'Osmosis', 'Porosity', 'Protons', 'Water'] | 7,526,110 | [['D05.750.078.562.272', 'D09.698.365.272'], ['D20.280.320', 'D26.255.165.320'], ['E05.196.867.519'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['G01.374.710'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resistance to cloxacillin among hospital staphylococci. | Cloxacillin-resistant strains of Staphylococcus aureus were detected by their ability to grow on agar containing 1.6 mug./ml. of cloxacillin, a more reliable method than the disc-diffusion test. At Sefton General Hospital, Liverpool, between 1963 and 1965, there was an increase in the number of infections among in-pati... | ['Bacteriophage Typing', 'Cloxacillin', 'Cross Infection', 'Humans', 'Penicillin Resistance', 'Staphylococcal Infections', 'Staphylococcus'] | 5,188,891 | [['E01.370.225.875.150.125.150', 'E05.200.875.150.125.150'], ['D02.065.589.099.750.625.150', 'D02.886.108.750.625.150', 'D03.633.100.300.750.625.150'], ['C01.248', 'C23.550.291.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.099.225.500.600', 'G06.225.347.500.600', 'G07.690.773.984.269.347.500.600'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnetic resonance imaging features of canine gliomatosis cerebri. | A retrospective, case series study was undertaken to identify magnetic resonance imaging (MRI) characteristics of gliomatosis cerebri in dogs. Fourteen dogs were included by review of histopathological records and contemporaneous MRI. On MRI, all lesions presented as ill-defined, intraaxial lesions within the left and ... | ['Animals', 'Brain Neoplasms', 'Dog Diseases', 'Dogs', 'Female', 'Magnetic Resonance Imaging', 'Male', 'Neoplasms, Neuroepithelial', 'Retrospective Studies'] | 29,110,365 | [['B01.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.350.825.500'], ['C04.557.465.625.600', 'C04.557.470.670', 'C04.557.580.625.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.71... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Investigation of SSEA-4 binding protein in breast cancer cells. | SSEA-4, a sialyl-glycolipid, has been commonly used as a pluripotent human embryonic stem cell marker, and its expression is correlated with the metastasis of some malignant tumors. However, there is no in-depth functional study related to the receptor and the role of this glycolipid. Here, we report the identification... | ['Breast Neoplasms', 'Cell Line, Tumor', 'Chromatography, High Pressure Liquid', 'Female', 'Flow Cytometry', 'Humans', 'Mass Spectrometry', 'Microarray Analysis', 'Polyethylene Glycols', 'Polysaccharides', 'Protein Binding', 'Stage-Specific Embryonic Antigens', 'Tacrolimus', 'Tacrolimus Binding Proteins'] | 23,574,147 | [['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.181.400.300'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
INTERMEDIATE CLEAVAGE PEPTIDASE55 Modifies Enzyme Amino Termini and Alters Protein Stability in Arabidopsis Mitochondria. | Precursor proteins containing mitochondrial peptide signals are cleaved after import by a mitochondrial processing peptidase. In yeast (Saccharomyces cerevisiae) and human (Homo sapiens), intermediate cleavage peptidase55 (ICP55) plays a role in stabilizing mitochondrial proteins by the removal of single amino acids fr... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'DNA, Bacterial', 'Gene Expression Regulation, Plant', 'Genetic Complementation Test', 'Metalloproteases', 'Mitochondria', 'Mitochondrial Proteins', 'Molecular Sequence Data', 'Mutagenesis, Insertional', 'Phenotype', 'Plant Development', 'Protein Stability'... | 25,862,457 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D13.444.308.212'], ['G05.308.375'], ['E05.393.281.526'], ['D08.811.277.656.675'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.575'], ['L01.453.245.667'], ['E05.393.420.601.550', 'G05.365.590.57... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2. | Mutations in the LRRK2 gene cause autosomal dominant Parkinson's disease. LRRK2 encodes a multi-domain protein containing a Ras-of-complex (Roc) GTPase domain, a C-terminal of Roc domain and a protein kinase domain. LRRK2 can function as a GTPase and protein kinase, although the interplay between these two enzymatic do... | ['Animals', 'Dimerization', 'Female', 'GTP Phosphohydrolases', 'Guanine Nucleotides', 'Guanosine Triphosphate', 'HSP90 Heat-Shock Proteins', 'Humans', 'Leucine-Rich Repeat Serine-Threonine Protein Kinase-2', 'Mutation, Missense', 'Neurons', 'Parkinson Disease', 'Phenotype', 'Protein Binding', 'Protein Structure, Tertia... | 23,241,358 | [['B01.050'], ['G02.206', 'G03.230'], ['D08.811.277.040.330'], ['D03.633.100.759.646.454', 'D13.695.667.454', 'D13.695.827.426'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', 'D13.695.827.426.504'], ['D12.776.580.216.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.534', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of obesity on outcomes in the management of localized adenocarcinoma of the esophagus and esophagogastric junction. | OBJECTIVE: Obesity trends in the Western world parallel the increased incidence of adenocarcinoma of the esophagus and esophagogastric junction. The implications of obesity on standard outcomes in the management of localized adenocarcinoma, particularly operative risks, have not been systematically addressed.METHODS: T... | ['Adenocarcinoma', 'Adult', 'Aged', 'Body Mass Index', 'Esophageal Neoplasms', 'Esophagectomy', 'Esophagogastric Junction', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Postoperative Complications', 'Retrospective Studies', 'Risk Assessment', 'Survival Analysis'] | 17,976,464 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.346'], ['A03.556.875.500.414', 'A03.556.875.875.330... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Policy changes and the methadone maintenance treatment system for opioid dependence in Ontario, 1996 to 2001. | BACKGROUND: Until recently, the availability of methadone treatment in Ontario, Canada was limited. In 1996, policy changes were introduced to increase the availability of treatment. The 5-year impact of these policy changes is assessed.METHODS: For these census data, descriptive statistics were used to examine changes... | ['Adult', 'Female', 'Health Policy', 'Humans', 'Longitudinal Studies', 'Male', 'Mental Health Services', 'Methadone', 'Narcotics', 'Ontario', 'Opioid-Related Disorders', 'Registries'] | 15,774,409 | [['M01.060.116'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['F04.408', 'N02.421.461'], ['D02.522.675'], ['D27.505.696.277.600', 'D27.505.696.663.8... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mechanism of HIV-1 Tat induced inhibition of antigen-specific T cell responsiveness. | HIV-1 Tat has been shown to have an inhibitory effect on the Ag-specific responsiveness of human peripheral T cells. We have previously demonstrated that this retroviral protein binds to and partially inhibits the enzymatic activity of dipeptidyl aminopeptidase type IV (DP IV), also known as CD26, which is expressed on... | ['Adult', 'Antigens, CD', 'Antigens, Differentiation, T-Lymphocyte', 'CD2 Antigens', 'CD28 Antigens', 'Dipeptidyl Peptidase 4', 'Dipeptidyl-Peptidases and Tripeptidyl-Peptidases', 'Gene Products, tat', 'Humans', 'Immune Sera', 'Interleukin-2', 'Lymphocyte Activation', 'Muromonab-CD3', 'Phytohemagglutinins', 'Receptors,... | 8,095,514 | [['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D23.050.301.264.894.090', 'D23.101.100.894.090'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['D08.811.277.656.350.350.126', 'D08.811.277.656.959.250', 'D23.050.301.264.894... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Quercetin enhances motility in aged and heat-stressed Caenorhabditis elegans nematodes by modulating both HSF-1 activity, and insulin-like and p38-MAPK signalling. | Quercetin is a yellow pigment that is found in many common dietary plants, and that protects against oxidative stress, inflammation, and arteriosclerosis. It has also been suggested to prolong the lifespan of, and enhance heat-stress tolerance in nematodes; thus, the present study investigated its effects on both the n... | ['Aging', 'Animals', 'Antioxidants', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'DNA-Binding Proteins', 'Forkhead Transcription Factors', 'Heat-Shock Response', 'Oxidative Stress', 'Quercetin', 'Signal Transduction', 'Transcription Factors', 'p38 Mitogen-Activated Protein Kinases'] | 32,881,908 | [['G07.345.124'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['D12.776.260'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G07.775.500'], ['G03.673', 'G07.775.750'], ['D03.383.663.283.266.450.284.777', 'D03.633.100.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mustard's operation for patients with ventriculoarterial concordance. Report of two cases and a cautionary tale. | Three patients with ventriculoarterial concordance and an abnormal atrioventricular connexion were investigated. One patient had total anomalous pulmonary venous connexion to a left vertical vein. In 1972 this was repaired and a ventricular septal defect was closed, but the presence of atrioventricular discordance was ... | ['Angiocardiography', 'Child, Preschool', 'Echocardiography', 'Female', 'Heart Defects, Congenital', 'Heart Septal Defects', 'Heart Ventricles', 'Humans', 'Infant', 'Male', 'Methods'] | 3,986,058 | [['E01.370.350.130.249', 'E01.370.350.700.060.050', 'E01.370.370.050.050', 'E01.370.370.380.050'], ['M01.060.406.448'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['C14.240.400.560', 'C14.280.400.560', 'C16.131.240.400.560'], ['A07.541.560']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Errors as allies: error management training in health professions education. | This paper adopts methods from the organisational team training literature to outline how health professions education can improve patient safety. We argue that health educators can improve training quality by intentionally encouraging errors during simulation-based team training. Preventable medical errors are inevita... | ['Administrative Personnel', 'Behavior Control', 'Humans', 'Medical Errors', 'Organizational Innovation', 'Patient Care Team', 'Patient Simulation', 'Safety Management', 'Systems Integration', 'Transfer, Psychology'] | 23,293,120 | [['M01.526.070'], ['E02.085', 'F04.047', 'I01.880.630.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.450'], ['N04.452.610'], ['N04.590.715'], ['I02.903.847.500'], ['N04.452.871.900', 'N06.850.135.060.075.800'], ['H01.770.787', 'L01.906.787'], ['F02.463.425.910']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Effect of abdominal distension on central and regional hemodynamics in neonatal lambs. | Elevations of intraabdominal pressure (IAP) can occur during surgical repair of gastroschisis and omphalocele and lead to ischemia of abdominal organs. We examined the effect of elevated IAP on central hemodynamics and regional abdominal organ blood flow, measured by radiolabeled microspheres, in 11 pentobarbital-anest... | ['Abdomen', 'Animals', 'Animals, Newborn', 'Cardiac Output', 'Digestive System', 'Female', 'Hemodynamics', 'Liver Circulation', 'Male', 'Oxygen Consumption', 'Pressure', 'Regional Blood Flow', 'Renal Circulation', 'Sheep', 'Splanchnic Circulation'] | 4,080,441 | [['A01.923.047'], ['B01.050'], ['B01.050.050.282'], ['E01.370.370.380.150', 'G09.330.380.124'], ['A03'], ['G09.330.380'], ['G09.330.100.881.552'], ['G03.680'], ['G01.374.715'], ['G09.330.100.780'], ['G08.852.725', 'G09.330.100.812'], ['B01.050.150.900.649.313.500.380.791'], ['G09.330.100.881']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of frog skin lipids in wound healing. | BACKGROUND: Frog skin has been sequentially and scientifically evaluated by our group for its wound healing efficiency. Owing to the complex structure of skin, attempts were being made to analyse the role of individual constituents in different phases of healing. Our earlier papers have shown the significance of frog s... | ['Administration, Cutaneous', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Dose-Response Relationship, Drug', 'Drug Discovery', 'Edema', 'Female', 'Granulation Tissue', 'Hypersensitivity', 'Immunity, Humoral', 'India', 'Injections, Intraperitoneal', 'Lipids', 'Materia Medica', 'Medicine, Traditional', 'Ranida... | 20,637,131 | [['E02.319.267.120.060'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['C23.888.277'], ['A10.165.450'], ['C20.543'], ['G12.450.050.420'], ['Z01.252.245.393'], ['E02.319.267.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
HEXIM1 Has Different Functions within Different RNA-Protein Complexes. | In this issue of Molecular Cell, Morchikh et al. (2017) describe a new ribonuclear complex built around HEXIM1 and the long non-coding RNA NEAT1. This complex regulates the innate immune response to DNA viruses and is distinct from the HEXIM1-7SK RNA complex that regulates transcription elongation. | ['HeLa Cells', 'Humans', 'Positive Transcriptional Elongation Factor B', 'RNA, Long Noncoding', 'RNA, Small Nuclear', 'RNA-Binding Proteins'] | 28,777,948 | [['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.626', 'D12.776.930.955.500'], ['D13.444.735.790.375'], ['D13.444.735.628.818', 'D13.444.735.790.552.937'], ['D12.776.157.725', 'D12.776.664.962']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A glycine-rich protein that facilitates exine formation during tomato pollen development. | Formation of the unique and highly diverse outer cell wall, or exine, of pollen is essential for normal pollen function and survival. However, little is known about the many contributing proteins and processes involved in the formation of this wall. The tomato gene LeGRP92 encodes for a glycine-rich protein produced sp... | ['Blotting, Western', 'Cell Wall', 'Gene Expression Regulation, Plant', 'Glycine', 'Lycopersicon esculentum', 'Microscopy, Electron, Scanning', 'Microscopy, Electron, Transmission', 'Plant Proteins', 'Plants, Genetically Modified', 'Pollen', 'RNA, Antisense'] | 20,033,228 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.183'], ['G05.308.375'], ['D12.125.481'], ['B01.650.940.800.575.912.250.908.500.322'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D12.776.765'], ['B01.650... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Derivation of haemodynamic information from ultrasonic recordings of aortic diameter changes. | An ultrasound phase-locked echo-tracking system was used for noninvasive measurements of diameter changes in the upper abdominal aorta of the anaesthetised cat. Comparisons were made between the noninvasively recorded diameter changes and central haemodynamic variables measured with inserted catheters and transducers. ... | ['Animals', 'Aorta, Abdominal', 'Blood Flow Velocity', 'Blood Pressure', 'Cardiac Catheterization', 'Cardiac Output', 'Cats', 'Hemodynamics', 'Male', 'Myocardial Contraction', 'Regional Blood Flow', 'Stroke Volume', 'Transducers', 'Ultrasonography', 'Vascular Resistance'] | 2,662,549 | [['B01.050'], ['A07.015.114.056.205'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.370.380.150', 'G09.330.380.124'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G09.330.380'], ['G09.330.580', 'G11.427.494... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A study on the risk factors of cerebral infarction as complication of type 2 diabetes mellitu patients]. | OBJECTIVE: Cerebral infarction, a common acute cereovascular disease, is one of the main complications of type 2 diabetes mellitus (DM). This paper is to explore the risk factors of cerebral infarction among type 2 DM patients.METHODS: A pair-matched case-control study was carried out. Data was analyzed with conditiona... | ['Adult', 'Aged', 'Cerebral Infarction', 'Diabetes Mellitus, Type 2', 'Diet', 'Exercise', 'Female', 'Humans', 'Hypertension', 'Lipids', 'Male', 'Middle Aged', 'Risk Factors'] | 11,860,880 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.650.240'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.15... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Morphologically distinct types of amyloid plaques point the way to a better understanding of Alzheimer's disease pathogenesis. | The details of the sequence of pathological events leading to neuron death in Alzheimer's disease (AD) are not known. Even the formation of amyloid plaques, one of the major histopathological hallmarks of AD, is not clearly understood; both the origin of the amyloid and the means of its deposition remain unclear. It is... | ['Aged', 'Alzheimer Disease', 'Amyloid', 'Blood-Brain Barrier', 'Brain', 'Extracellular Space', 'Humans', 'Immunohistochemistry', 'Inflammation', 'Intracellular Space', 'Necrosis', 'Neurons', 'Plaque, Amyloid'] | 20,121,465 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D05.500.049', 'D12.776.049'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.5... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The rehabilitation of children with anti-N-methyl-D-aspartate-receptor encephalitis: a case series. | Anti-N-methyl-D-aspartate (NMDA)-receptor encephalitis is a serious, complex, and potentially fatal disease in children. Children with this condition frequently present with altered mental status, rapid functional deterioration, and seizures. Despite aggressive treatment with immune therapy such as corticosteroids, int... | ['Adolescent', 'Anti-N-Methyl-D-Aspartate Receptor Encephalitis', 'Child', 'Child, Preschool', 'Female', 'Hospitalization', 'Humans', 'Male', 'Recovery of Function', 'Rehabilitation Centers', 'Treatment Outcome'] | 22,415,341 | [['M01.060.057'], ['C04.588.614.550.112', 'C04.730.856.112', 'C10.228.140.430.124', 'C10.574.781.249', 'C20.111.258.124'], ['M01.060.406'], ['M01.060.406.448'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.757'], ['N02.278.808'], ['E01.789.800', 'N04.761.559.590.800', 'N05.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A 10-year retrospective study of infective endocarditis at a university hospital with special regard to the timing of surgical evaluation in S. viridans endocarditis. | A total of 154 episodes of infective endocarditis (IE) in 149 patients were studied retrospectively with special regard to the major aetiological groups and the surgical evaluation. There were 136 episodes of native valve endocarditis (NVE) (88%) and 18 episodes of prosthetic valve endocarditis (PVE) (12%). Three major... | ['Abscess', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Endocarditis, Bacterial', 'Female', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Staphylococcus aureus', 'Streptococcus', 'Time Factors'] | 10,381,225 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of translationally controlled tumor protein mRNA in human colon cancer. | The translationally controlled tumor protein (TCTP) was first identified as a tumor-associated protein. Here we described the expression profile of TCTP mRNA using a panel of normal human tissues. We also investigated the cell-cycle-dependent expression of the TCTP mRNA using synchronized cultures of Saccahromyces cere... | ['Adenocarcinoma', 'Animals', 'Biomarkers, Tumor', 'Blotting, Northern', 'Calcium-Binding Proteins', 'Cell Cycle', 'Colonic Neoplasms', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'RNA, Messenger', 'Saccharomyces cerevisiae', 'Transplantation, Heterologo... | 10,880,768 | [['C04.557.470.200.025'], ['B01.050'], ['D23.101.140'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D12.776.157.125'], ['G04.144'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['G05.308.370'], ['B01.050.150.900... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain. | P2X4 receptor (P2X4R) is an ion channel gated by adenosine 5'-triphosphate. Here we report the presence and the distribution of P2X4R in rat spinal cord by immunohistochemical analysis in an inflammatory pain model. Peripheral inflammation was induced by subcutaneous injection of 4% formalin into the rat hindpaw. Morph... | ['Animals', 'Gene Expression Regulation', 'Inflammation', 'Lumbosacral Region', 'Male', 'Microglia', 'Pain', 'Pain Measurement', 'Rats', 'Rats, Inbred Lew', 'Receptors, Purinergic P2', 'Receptors, Purinergic P2X4', 'Spinal Cord'] | 15,885,314 | [['B01.050'], ['G05.308'], ['C23.550.470'], ['A01.923.176.519'], ['A08.637.400', 'A11.650.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E01.370.600.550.324'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.280', 'B01.050.150.900.649.313.992.635.505.700.400.280'], ['D12.776.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Here's a look at status of court rulings on ADA. First key decision involved HIV-infected person. | The U.S. Supreme Court first issued a decision on HIV and the Americans With Disabilities Act (ADA) on June 25, 1998, and for AIDS advocates it was a high point in their efforts to provide legal protection to HIV-infected people. However, there subsequently have been some disappointing ADA decisions by the nation's hig... | ['Disabled Persons', 'HIV Infections', 'Humans', 'Supreme Court Decisions'] | 15,446,222 | [['M01.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583.858']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Late onset of a facial variant of steatocystoma multiplex - calretinin as a specific marker of the follicular companion cell layer. | Steatocystoma multiplex is a rare,almost exclusively autosomal dominant disease of the sebaceous glands. The sites of predilection are the sternal region, upper back, axillae and proximal parts of the extremities. A 78-year-old woman developed multiple yellowish nodules only on the face over a few months. Histology rev... | ['Aged', 'Biomarkers', 'Calbindin 2', 'Facial Dermatoses', 'Female', 'Hair Follicle', 'Humans', 'Rare Diseases', 'S100 Calcium Binding Protein G', 'Sebaceous Gland Diseases'] | 18,266,860 | [['M01.060.116.100'], ['D23.101'], ['D12.776.157.125.090.249'], ['C17.800.271'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.906'], ['D12.776.157.125.090.500', 'D12.776.157.125.750.750'], ['C17.800.794']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of age on ventricular-vascular coupling. | The effects of age on the interrelation between the physical properties of the arterial tree (aortic input impedance) and left ventricular performance (cardiac output) were studied in 45 subjects, aged 19 to 62 years, without apparent cardiovascular disease. Ascending aortic pulsatile pressure and blood flow velocity w... | ['Adult', 'Aging', 'Aorta', 'Blood Flow Velocity', 'Blood Pressure', 'Cardiac Catheterization', 'Cardiac Output', 'Elasticity', 'Hemodynamics', 'Humans', 'Middle Aged', 'Stroke Volume', 'Systole', 'Vascular Resistance'] | 3,984,897 | [['M01.060.116'], ['G07.345.124'], ['A07.015.114.056'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.370.380.150', 'G09.330.380.124'], ['G01.374.590'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in the expression of cytochromes P450 and nuclear receptors in the liver of genetically diabetic db/db mice. | Physiological and pathophysiological conditions often affect the expression of drug metabolizing enzymes such as cytochromes P450 (P450s). Diabetes is one such factor and it is of great interest to understand its effects on drug metabolism, since diabetic patients generally have increased need for pharmacotherapy. We h... | ['Animals', 'Base Sequence', 'Blotting, Western', 'Cytochrome P-450 Enzyme System', 'DNA Primers', 'Diabetes Mellitus, Experimental', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Receptors, Cytoplasmic and Nuclear', 'Reverse Transcriptase Polymerase Chain Reaction'] | 16,880,618 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C18.452.394.750.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mathematical models of human paralyzed muscle after long-term training. | Spinal cord injury (SCI) results in major musculoskeletal adaptations, including muscle atrophy, faster contractile properties, increased fatigability, and bone loss. The use of functional electrical stimulation (FES) provides a method to prevent paralyzed muscle adaptations in order to sustain force-generating capacit... | ['Adult', 'Exercise', 'Humans', 'Male', 'Models, Biological', 'Muscle, Skeletal', 'Muscular Atrophy', 'Paresis', 'Spinal Cord Injuries', 'Time Factors'] | 17,316,653 | [['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['A02.633.567', 'A10.690.552.500'], ['C10.597.613.612', 'C23.300.070.500', 'C23.888.592.608.612'], ['C10.597.636', 'C23.888.592.643'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['G01.910.857']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Pasteurella multocida infections: bites by dogs or cats?]. | Annually 50,000 to 100,000 animal bites are seen by physicians in the Netherlands. Infections of these bite wounds frequently occur. Pasteurella multocida is one of the main causes of these infections and many serious complications may occur. We present 3 patients with disturbances in wound healing after animal bites o... | ['Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Bites and Stings', 'Female', 'Humans', 'Middle Aged', 'Pasteurella', 'Pasteurella Infections', 'Skin Transplantation', 'Wound Infection'] | 2,002,857 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['C25.723.127', 'C26.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['B03.440.450.600.600', 'B03.660.250.550.590'], ['C01.150.252.400.700.662'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['C01.947'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The 2009 influenza A (H1N1) pandemic. Management and vaccination strategies in The Netherlands. | Prior to 2009, The Netherlands had prepared itself extensively for a potential pandemic. Multidisciplinary guidelines had been drafted to control transmission and limit adverse outcomes for both a phase of early incidental introduction and for a phase with widespread transmission. The Ministry of Health had ensured a s... | ['Disease Notification', 'Health Communication', 'Health Planning', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Mass Vaccination', 'Netherlands', 'Pandemics', 'Population Surveillance'] | 23,275,958 | [['E05.318.362', 'N06.850.520.373', 'N06.850.780.200.262'], ['L01.143.350', 'N02.208'], ['N03.349', 'N03.706.615.302'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['E02.095.465.425.400.530.890.500', 'E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Pelvic insufficiency fractures in patients with pelvic irradiation. | BACKGROUND: Insufficiency fractures (IF) occur as a result of normal physiological stress on bones with deficient elastic resistance. Pelvic insufficiency fractures are a complication of osteoporosis due to postmenopausal status, high dose of corticosteroids, or local irradiation. They are important because differentia... | ['Adenocarcinoma', 'Aged', 'Carcinoma, Squamous Cell', 'Diagnosis, Differential', 'Endometrial Neoplasms', 'Female', 'Fractures, Bone', 'Humans', 'Middle Aged', 'Pelvic Bones', 'Radiography', 'Radionuclide Imaging', 'Rectal Neoplasms', 'Sarcoma', 'Uterine Cervical Neoplasms'] | 10,219,795 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.171'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.835.232.043.825'], ['E01.370.350.700'], ... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fractal nature of regional myocardial blood flow heterogeneity. | Spatial variation in regional flows within the heart, skeletal muscle, and in other organs, and temporal variations in local arteriolar velocities and flows is measurable even with low resolution techniques. A problem in the assessment of the importance of such variations has been that the observed variance increases w... | ['Animals', 'Coronary Circulation', 'Mathematics', 'Models, Cardiovascular', 'Rabbits', 'Regional Blood Flow', 'Regression Analysis', 'Sheep', 'Stochastic Processes'] | 2,766,485 | [['B01.050'], ['G09.330.100.324'], ['H01.548'], ['E05.599.395.161'], ['B01.050.150.900.649.313.968.700'], ['G09.330.100.780'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['B01.050.150.900.649.313.500.380.791'], ['E05.318.740.996', 'G17.830', 'N05.715.360.750.770', 'N06.850.520.830.996']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Ambiguous genitals and the choice of gender. | In 8 children with ambiguous external genitals, sex chromosome, hormonal and histological examinations were performed. On this basis the registered sex and the surname of the child were changed from the registered male to female in 3 cases and from female to male in one case. Diagnosis and the decision about the gender... | ['Adrenal Hyperplasia, Congenital', 'Androgen-Insensitivity Syndrome', 'Child, Preschool', 'Disorders of Sex Development', 'Dysgerminoma', 'Female', 'Genitalia', 'Gonads', 'Humans', 'Hypospadias', 'Infant', 'Infant, Newborn', 'Karyotyping', 'Male', 'Sex Chromosome Aberrations', 'Sex Determination Analysis', 'Testicular... | 735,802 | [['C12.706.316.090.500', 'C13.351.875.253.090.500', 'C16.131.939.316.129.500', 'C16.320.033', 'C16.320.565.925.249', 'C18.452.648.925.249', 'C19.053.440', 'C19.391.119.090.500'], ['C12.706.316.096.500', 'C13.351.875.253.096.500', 'C16.131.939.316.096.500', 'C16.320.322.061', 'C19.391.119.096.500'], ['M01.060.406.448'],... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. | The chemical diversity and known safety profiles of drugs previously tested in humans make them a valuable set of compounds to explore potential therapeutic utility in indications outside those originally targeted, especially neglected tropical diseases. This practice of "drug repurposing" has become commonplace in aca... | ['Animals', 'Antiprotozoal Agents', 'Cryptosporidiosis', 'Cryptosporidium', 'Databases, Pharmaceutical', 'Drug Discovery', 'Drug Evaluation, Preclinical', 'Drug Repositioning', 'Female', 'High-Throughput Screening Assays', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'Small Molecule Libraries'] | 30,282,735 | [['B01.050'], ['D27.505.954.122.250.100'], ['C01.610.432.269', 'C01.610.701.688.235', 'C01.610.752.250.269', 'C01.610.752.625.235', 'C06.405.469.452.269', 'C22.674.710.235'], ['B01.043.075.189.250.150.160'], ['L01.313.500.750.300.188.400.400', 'L01.470.750.750.400'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
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