Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[Clinical and angiographic characteristics of acute anteroseptal and upper lateral myocardial infarction: obliquous infarction; proposal of a new denomination for a specific type of infarction]. | PURPOSE: Analysis of clinical and angiographic characteristics of oblique (anteroseptal and high lateral) myocardial infarction.MATERIAL AND METHODS: Forty-two patients, 33 men, aged 30 to 79 years (mean 57) with oblique myocardial infarction were clinically evaluated and through coronary arteriography between ten day ... | ['Adult', 'Aged', 'Collateral Circulation', 'Electrocardiography', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Stroke Volume', 'Terminology as Topic'] | 2,264,766 | [['M01.060.116'], ['M01.060.116.100'], ['G09.330.100.248'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pretreatment with 1,25-dihydroxycholecalciferol enhances thyrotropin-releasing hormone- and inositol 1,4,5-trisphosphate-induced release of sequestered Ca2+ in permeabilized GH4C1 pituitary cells. | In GH4C1 cells 1,25-dihydroxycholecalciferol [1,25-(OH)2D3] has been shown to enhance the TRH- and bombesin-induced increase in intracellular Ca2+ ([Ca2+]i). The aim of the present study was to investigate whether this increase in [Ca2+]i could be due to enhanced release of sequestered Ca2+ in cells pretreated with 1,2... | ['Animals', 'Calcitriol', 'Calcium', 'Cell Line', 'Cell Membrane Permeability', 'Heparin', 'Inositol 1,4,5-Trisphosphate', 'Pituitary Gland', 'Rats', 'Terpenes', 'Thapsigargin', 'Thyrotropin-Releasing Hormone'] | 1,396,313 | [['B01.050'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['G03.143.335', 'G04.175'], ['D09.698.373.400'], ['D02.033.800.519.400.350', 'D09.85... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
iMonDB: Mass Spectrometry Quality Control through Instrument Monitoring. | Over the past few years, awareness has risen that for mass-spectrometry-based proteomics methods to mature into everyday analytical and clinical practices, extensive quality assessment is mandatory. A currently overlooked source of qualitative information originates from the mass spectrometer itself. Apart from the act... | ['Databases, Factual', 'Equipment Failure Analysis', 'Humans', 'Mass Spectrometry', 'Proteomics', 'Quality Control', 'Software'] | 25,798,920 | [['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['J01.897.608'], ['L01.224.900']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial. | UNLABELLED: Hepatorenal syndrome (HRS), a serious complication of cirrhosis, is associated with high mortality without treatment. Terlipressin with albumin is effective in the reversal of HRS. Where terlipressin is not available, as in the United States, midodrine and octreotide with albumin are used as an alternative ... | ['Aged', 'Albumins', 'Analysis of Variance', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Hepatorenal Syndrome', 'Humans', 'Infusions, Intravenous', 'Kaplan-Meier Estimate', 'Kidney Function Tests', 'Liver Function Tests', 'Lypressin', 'Male', 'Middle Aged', 'Midodrine', 'Octreotide', 'Predictive Value ... | 25,644,760 | [['M01.060.116.100'], ['D12.776.034'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E02.319.310'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C06.552.465', 'C12.777.419.291', 'C13.351.968.419.291'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Dental caries: new data from imperial Roman necropolis]. | The relations between oral disease and living conditions and health of a population are important to reconstruct the biological status of a population. The incidence of caries was considered by the calculation of frequencies for individual and for tooth but also by the estimate of index of caries et extraction in four ... | ['Dental Caries', 'History, Ancient', 'Humans', 'Oral Hygiene', 'Roman World'] | 19,069,071 | [['C07.793.720.210'], ['K01.400.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547.600', 'E06.761.726'], ['I01.076.201.450.226.800.500']] | ['Diseases [C]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of the quality of food products and rations]. | The article delivers information about method of calculation from estimation quality food products and rations nourishment from different contingents feeding. Investigations conduct on the example meat-fish wares. Elaborated and scientific grounded permit biology of full valve products nourishment. | ['Diet', 'Fish Products', 'Food Analysis', 'Meat Products', 'Quality Control'] | 9,214,142 | [['G07.203.650.240'], ['G07.203.300.600.875.400', 'J02.500.600.875.400'], ['E05.362', 'J01.576.423.850.100'], ['G07.203.300.600.500', 'J02.500.600.500'], ['J01.897.608']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Correlation between the age at repair and speech outcome in patients with isolated cleft palate. | The effect of the age at primary palatal repair on the speech of 3-year old children with isolated cleft palate was assessed. The group comprised 108 consecutive children whose palates were repaired at the mean ages of 12.9 (n = 45), 18.5 (n = 18) and 22.1 months (n = 45). Signs of cleft palate speech and the degree of... | ['Age Factors', 'Articulation Disorders', 'Child, Preschool', 'Cleft Palate', 'Humans', 'Infant', 'Palate', 'Reoperation', 'Speech', 'Treatment Outcome', 'Velopharyngeal Insufficiency'] | 1,626,233 | [['N05.715.350.075', 'N06.850.490.250'], ['C10.597.606.150.500.800.150', 'C23.888.592.604.150.500.800.150'], ['M01.060.406.448'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.131.850.500.460.185', 'C16.... | ['Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Comparison of dewaterability and floc structure of synthetic sludge with activated sludge. | This work compared the appearance, dewaterability, floc size, fractal dimensions derived from free-settling test and light-scattering test, and detailed structural information of floc interior including porosity, Sierpinski carpet fractal dimension, and the fractal dimension of the pore boundaries of a synthetic sludge... | ['Flocculation', 'Sewage', 'Waste Disposal, Fluid', 'Water'] | 15,747,595 | [['E05.196.150.347', 'G02.159.347'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cloning of a gene encoding hydroxyquinol 1,2-dioxygenase that catalyzes both intradiol and extradiol ring cleavage of catechol. | Two Escherichia coli transformants with catechol 1,2-dioxygenase activity were selected from a gene library of the benzamide-assimilating bacterium Arthrobacter species strain BA-5-17, which produces four catechol 1,2-dioxygenase isozymes. A DNA fragment isolated from one transformant contained a complete open reading ... | ['Amino Acid Sequence', 'Base Sequence', 'Catalysis', 'Catechols', 'Cloning, Molecular', 'Dioxygenases', 'Hydrolysis', 'Molecular Sequence Data', 'Open Reading Frames', 'Oxygenases', 'Phylogeny', 'Sequence Homology, Amino Acid', 'Substrate Specificity'] | 10,380,628 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.130'], ['D02.455.426.559.389.657.166'], ['E05.393.220'], ['D08.811.682.690.416'], ['G02.380'], ['L01.453.245.667'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['D08.811.682.690'], ['G05.697', 'G16.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Comparison of the endocrine response under 2 kinds of anesthesia: neuroleptanalgesia of the chlorprothixene-dextromoramide type and venous anesthesia of the type alfadione-fentanyl]. | In 14 patients anaesthetized before undergoing an orthopedic surgical intervention, the variations induced by anaesthesia in the 17 hydroxycorticosterone rate, catecholamine, somatotropic hormone (STH), insulin, glycemia, free fatty acids and thyrotropin (TSH), all these variations were studied before the surgery. The ... | ['Alfaxalone Alfadolone Mixture', 'Anesthesia, Intravenous', 'Anesthetics', 'Catecholamines', 'Chlorprothixene', 'Dextromoramide', 'Epinephrine', 'Fentanyl', 'Growth Hormone', 'Humans', 'Hydrocortisone', 'Insulin', 'Insulin Secretion', 'Neuroleptanalgesia', 'Norepinephrine', 'Pituitary-Adrenal System', 'Thyrotropin'] | 5,035 | [['D04.210.500.745.558.050'], ['E03.155.308'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D02.886.952.250', 'D03.633.300.953.704.250'], ['D03.383.533.640.250'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.45... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical features and prognostic factors associated with adrenocortical carcinoma: Lahey Clinic Medical Center experience. | Adrenocortical carcinoma is a rare tumor associated with a commonly poor prognosis. However, data on the natural history and response to therapy of patients with this malignancy have often been conflicting. Our objective of this retrospective study was to evaluate the clinical course and survival of patients with adren... | ['Adolescent', 'Adrenal Cortex Neoplasms', 'Adrenocortical Carcinoma', 'Adult', 'Aged', 'Child', 'Female', 'Humans', 'Male', 'Massachusetts', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models', 'Retrospective Studies', 'Survival Rate'] | 10,651,352 | [['M01.060.057'], ['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['C04.557.470.200.025.152', 'C04.588.322.078.265.750', 'C19.053.098.265.750', 'C19.053.347.500.750', 'C19.344.078.265.750'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effects of Cassia obtusifolia (sicklepod) extracts and anthraquinones on muscle mitochondrial function. | Naturally occurring quinones and quinone-containing extracts of seeds of the toxic plant Cassia obtusifolia (sicklepod) affected muscle mitochondrial function. Aqueous suspensions and organic extracts of C. obtusifolia seeds slightly elevated plasma creatine kinase levels of Sprague-Dawley rats. These extracts were ana... | ['Animals', 'Anthraquinones', 'Body Weight', 'Cassia', 'Chromatography, Gas', 'Cytochrome Reductases', 'In Vitro Techniques', 'Male', 'Mitochondria, Muscle', 'Plant Extracts', 'Plants, Medicinal', 'Rats', 'Rats, Inbred Strains', 'Xanthine Oxidase'] | 2,749,752 | [['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.650.940.800.575.912.250.401.100'], ['E05.196.181.349'], ['D08.811.682.608.191'], ['E05.481'], ['A11.284.430.214.190.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical Relevance of Bone Density Values from CT Related to Dental Implant Stability: A Retrospective Study. | Purpose: The majority of the techniques used to assess the primary implant stability are subjective and empirical and can be used during or after the surgery. The aim of this study is to evaluate the bone density prior to surgery, in order to give recommendations to the clinician about the best surgical technique and t... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bone Density', 'Dental Implantation, Endosseous', 'Dental Implants', 'Female', 'Humans', 'Male', 'Maxilla', 'Middle Aged', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Torque', 'Young Adult'] | 29,955,608 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G11.427.100'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.645'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[The "COPD emergency 2003" study: a description of the hospital management of exacerbations of COPD]. | CURRENT SITUATION: Despite its impact on public health and numerous recommendations COPD remains under-diagnosed and its care pathways are not well known. Exacerbations are common presentations of the illness and contribute greatly to its impact on the health of the individual and the community. Despite this the method... | ['Adult', 'Data Collection', 'Emergency Treatment', 'Hospitalization', 'Humans', 'Practice Guidelines as Topic', 'Prospective Studies', 'Pulmonary Disease, Chronic Obstructive', 'Severity of Illness Index'] | 15,260,044 | [['M01.060.116'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E02.365'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Investigations of ferric heme cyanide photodissociation in myoglobin and horseradish peroxidase. | The photodissociation of cyanide from ferric myoglobin (MbCN) and horseradish peroxidase (HRPCN) has definitively been observed. This has implications for the interpretation of ultrafast IR (Helbing et al. Biophys. J. 2004, 87, 1881-1891) and optical (Gruia et al. Biophys. J. 2008, 94, 2252-2268) studies that had previ... | ['Cyanides', 'Heme', 'Horseradish Peroxidase', 'Models, Molecular', 'Myoglobin', 'Photolysis'] | 23,472,676 | [['D01.248.497.158.291', 'D01.625.400.100'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D08.811.682.732.512'], ['E05.599.595'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['G02.740.685']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thymoma arising in the wall of a thymic cyst. | A 54-year-old male, non smoker, began to suffer from persistent dyspnoea and fever. X-ray and CT scan showed a cystic lesion located in the left anterior mediastinum. This lesion was removed instead of the initially scheduled surgical resection with video-assisted thoracoscopic surgery (VATS) preceded by fine needle as... | ['Biopsy, Fine-Needle', 'Contraindications', 'Dyspnea', 'Humans', 'Male', 'Mediastinal Cyst', 'Middle Aged', 'Thoracic Surgery, Video-Assisted', 'Thymoma', 'Thymus Neoplasms', 'Tomography, X-Ray Computed'] | 19,475,891 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E02.208'], ['C08.618.326', 'C23.888.852.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
GSK3â controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug. | Glycogen synthase kinase 3 beta (GSK3â) is highly inactivated in epithelial cancers and is known to inhibit tumor migration and invasion. The zinc-finger-containing transcriptional repressor, Slug, represses E-cadherin transcription and enhances epithelial-mesenchymal transition (EMT). In this study, we find that the G... | ['Animals', 'Blotting, Western', 'Cadherins', 'Carcinoma, Non-Small-Cell Lung', 'Cell Movement', 'Cell Proliferation', 'Cohort Studies', 'Epithelial-Mesenchymal Transition', 'Gene Expression Regulation, Neoplastic', 'Glycogen Synthase Kinase 3', 'Glycogen Synthase Kinase 3 beta', 'Humans', 'Immunoenzyme Techniques', 'I... | 23,851,495 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G04.198', 'G07.568.500.180'], ['G04.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Training evaluation of the Secondary 3 Training Program of the Project P.A.T.H.S. in Hong Kong. | A total of 235 participants from 48 schools participated in a 3-day training program designed to train teachers and social workers to implement the Secondary 3 Program of the Project P.A.T.H.S. in Hong Kong. At the end of the training program, participants were invited to respond to a structured subjective outcome eval... | ['Adolescent', 'Adolescent Development', 'Education, Professional', 'Health Knowledge, Attitudes, Practice', 'Health Promotion', 'Hong Kong', 'Humans', 'Inservice Training', 'Program Evaluation', 'Social Problems'] | 22,416,501 | [['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['I02.358'], ['F01.100.150.500', 'N05.300.150.410'], ['I02.233.332.445', 'N02.421.726.407.579'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['I01.880.735']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Emergency surgery in colorectal cancer: experience of a county hospital at a 10-year interval. Comparison of immediate postoperative results. | UNLABELLED: A great majority of procedures for colorectal cancer are performed as emergencies, implying a high morbidity and mortality. The aim of this study is to compare the immediate postoperative results of emergency procedures for colorectal cancer between a 10 year interval in a single centre. We performed a retr... | ['Aged', 'Aged, 80 and over', 'Colectomy', 'Colorectal Neoplasms', 'Emergency Service, Hospital', 'Female', 'Hospitals, County', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Postoperative Period', 'Retrospective Studies', 'Risk Factors', 'Romania', 'Survival Rate', 'Treatment Outcome'] | 24,956,338 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.219'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N02.278.421.510.100'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Antireceptor antiserum causes specific inhibition of reactivity to rat histocompatibility antigens. | The antigen receptor of lymphocytes destined to form antibody appears to have the characteristics of the immunoglobulin produced. Antibody directed against the combining region of this immunoglobulin should interact with the combining region of the cell receptor for the antigen. Purified Lewis rat alloantibody prepared... | ['Animals', 'Antibodies, Anti-Idiotypic', 'Antibody Formation', 'Antigen-Antibody Reactions', 'Binding Sites, Antibody', 'Erythrocytes', 'Graft vs Host Reaction', 'Hemagglutination Tests', 'Histocompatibility Antigens', 'Hybridization, Genetic', 'Immune Sera', 'Immune Tolerance', 'Immunization', 'Immunization, Passive'... | 4,148,704 | [['B01.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['G12.450.050.370.250'], ['G12.122'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G12.875.402'], ['E01.370.225.812.735.050.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Parkinson disease and risk of mortality: a prospective comorbidity-matched cohort study. | OBJECTIVE: To evaluate the association between Parkinson disease (PD) and mortality after adjustment for comorbidities.METHODS: We conducted a matched cohort analysis among 22,071 participants in the Physicians' Health Study. Five hundred sixty incident PD cases were identified by self-report. We used a modified Charls... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Cohort Studies', 'Comorbidity', 'Diabetes Mellitus', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Parkinson Disease', 'Proportional Hazards Models', 'Prospective Studies', 'Randomized Controlled Trials as Topic', 'Risk Factors', '... | 18,413,567 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C18.452.394.750', 'C19.246'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Spectrofluorimetric methods for the determination of gemifloxacin in tablets and spiked plasma samples. | Two new, sensitive and selective spectrofluorimetric methods have been developed for the determination of gemifloxacin (GFX) in tablets and spiked plasma samples. Gemifloxacin, as a primary amine compound, reacts with 7-chloro-4-nitrobenzofurazon (NBD-Cl) (for method A) and fluorescamine (for method B) which are a high... | ['Anti-Bacterial Agents', 'Fluoroquinolones', 'Gemifloxacin', 'Humans', 'Naphthyridines', 'Reference Standards', 'Spectrometry, Fluorescence', 'Tablets'] | 20,981,565 | [['D27.505.954.122.085'], ['D03.633.100.810.835.322'], ['D03.633.100.612.250', 'D03.633.100.810.835.322.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.612'], ['E05.978.808'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['D26.255.830']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunoregulatory effects of human cord blood T lymphocytes on mixed lymphocyte reaction. | Fetuses of outbred mammalian species can survive despite disparities of participants' histocompatibility antigens. During pregnancy, maternal immune response is supposed to be suppressed by various immune suppressive mechanisms. In order to know whether fetal lymphocytes can suppress the maternal immune reaction, we in... | ['Female', 'Fetal Blood', 'Histocompatibility', 'Humans', 'Immunosuppression', 'Infant, Newborn', 'Lymphocyte Culture Test, Mixed', 'Pregnancy', 'T-Lymphocytes', 'T-Lymphocytes, Regulatory'] | 2,943,844 | [['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['G12.875.519'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ['M01.060.703.520'], ['E01.370.225.812.385.475', 'E05.200.812.385.475', 'E05.478.594.385.429'], ['G08.686.784.769'], ['A11.118.637.555.567.569', 'A15.145.229.637.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
White men and weak masculinity: men in the public asylums in Victoria, Australia, and New Zealand, 1860s-1900s. | This article reveals a set of formulations of masculine identity through the fragments of extant casebook evidence from nineteenth-century psychiatric institutions in Victoria, Australia, and Auckland, New Zealand. It shows that some patterns in the identification of masculinity and insanity emerge, also highlighting t... | ['Colonialism', 'History, 19th Century', 'History, 20th Century', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Masculinity', 'Mental Disorders', 'Neurosyphilis', 'New Zealand', 'Sexuality', 'Victoria'] | 25,395,445 | [['I01.696.116'], ['K01.400.504.937'], ['K01.400.504.968'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.813.376', 'F01.393.446.250.750', 'F01.752.747.385.200.750'], ['F03'], ['C01.150.252.223.600', 'C01.150.252.400.794.840.500.750', 'C01.150.252.400.840.500.750', 'C01.207.180.600... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
In situ RT-PCR allows the detection of ornithine decarboxylase mRNA in paraffin embedded archival human hyperplastic breast tissues. | Expression of ornithine decarboxylase (ODC) is induced by c-Myc oncoprotein and is required for cell proliferation and tumour growth. We have studied the expression of ODC mRNA by in situ hybridisation and in situ RT-PCR in archival human hyperplastic breast tissues. A very low signal was detected by in situ hybridisat... | ['Breast', 'Epithelial Cells', 'Humans', 'Hyperplasia', 'In Situ Hybridization', 'Ornithine Decarboxylase', 'Paraffin Embedding', 'Permeability', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Tissue Fixation'] | 10,563,250 | [['A01.236'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['D08.811.520.224.125.425'], ['E01.370.225.500.620.760.440.610', 'E01.370.225.750.600.760.... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conformational changes induced in dihydrofolate reductase by folates, pyridine nucleotide coenzymes, and methotrexate. | Dihydrofolate reductase (EC 1.5.1.3; 5,6,7,8-tetrahydrofolate:NADP(+) oxidoreductase) from antifolate-resistant Lactobacillus casei has been isolated in pure form and examined in solution by high resolution proton magnetic resonance spectroscopy. The 220 MHz proton magnetic resonance spectrum of this small enzyme (abou... | ['Folic Acid', 'Lactobacillus casei', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Methotrexate', 'NADP', 'Protein Conformation', 'Protein Denaturation', 'Tetrahydrofolate Dehydrogenase', 'Urea'] | 4,154,440 | [['D03.633.100.733.631.400'], ['B03.353.750.450.475.225', 'B03.510.460.400.410.475.475.225', 'B03.510.550.450.475.225'], ['D27.720.470.480'], ['E05.196.867.519'], ['D03.633.100.733.631.192.500'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['G02.111.570.820.709'], ['G01... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Noninvasive hemodynamic monitoring via the integration of data obtained by ECG, aortic flow by Doppler esophageal probe and by finger plethysmography]. | The aims of this work are to describe the general and technical characteristics of a new device for the noninvasive monitoring of patients in intensive care and during general anaesthesia, and the results concerning the reliability of this method. An ultrasonic esophageal probe and an echo-Doppler device have been used... | ['Anesthesia, General', 'Aorta, Thoracic', 'Critical Care', 'Electrocardiography', 'Esophagus', 'Fingers', 'Hemodynamics', 'Humans', 'Monitoring, Intraoperative', 'Plethysmography', 'Ultrasonography'] | 2,247,249 | [['E03.155.197'], ['A07.015.114.056.372'], ['E02.760.190', 'N02.421.585.190'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A03.556.875.500'], ['A01.378.800.667.430'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.510', 'E04.510'], ['E01.370.370.610'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Association mapping of iron deficiency chlorosis loci in soybean (Glycine max L. Merr.) advanced breeding lines. | Association mapping is an alternative to mapping in a biparental population. A key to successful association mapping is to avoid spurious associations by controlling for population structure. Confirming the marker/trait association in an independent population is necessary for the implementation of the marker in other ... | ['Biomarkers', 'Breeding', 'Chromosome Mapping', 'Chromosomes, Plant', 'Iron', 'Minisatellite Repeats', 'Models, Genetic', 'Plant Diseases', 'Quantitative Trait Loci', 'Soybeans'] | 18,292,984 | [['D23.101'], ['E05.820.150', 'G05.090'], ['E05.393.183'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G02.111.570.080.708.800.550', 'G05.360.080.708.800.550', 'G05.360.340.024.850.550'], ['E05.599.395.397'], ['G15.610'], ['G05.360.340.024.380.937'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PI3K activation is required for PMA-directed activation of cSrc by AFAP-110. | Activation of PKCalpha will induce the cSrc binding partner AFAP-110 to colocalize with and activate cSrc. The ability of AFAP-110 to colocalize with cSrc is contingent on the integrity of the amino-terminal pleckstrin homology (PH1) domain, while the ability to activate cSrc is dependent on the integrity of its SH3 bi... | ['Animals', 'Cell Membrane', 'Cell Movement', 'Chromones', 'Enzyme Activation', 'Enzyme Activators', 'Fibroblasts', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Microfilament Proteins', 'Morpholines', 'NIH 3T3 Cells', 'Phosphatidylinositol 3-Kinases', 'Phosphoinositide-3 Kinase Inhibitors', 'Phosphoproteins', 'Prot... | 17,360,811 | [['B01.050'], ['A11.284.149'], ['G04.198', 'G07.568.500.180'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['G02.111.263', 'G03.328'], ['D27.505.519.374'], ['A11.329.228'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delayed implantation of demineralized bone powder after local irradiation in rats. | Previous studies have shown that osteoinduction is inhibited when demineralized bone powder (DBP) is implanted within 48 hours of local irradiation (i.e., when the acute effects of radiation injury are present). This study sought to determine whether normal osteoinduction can proceed if the implantation of DBP is delay... | ['Animals', 'Bone Transplantation', 'Bone and Bones', 'Dose-Response Relationship, Radiation', 'Male', 'Osteogenesis', 'Radiation Dosage', 'Rats', 'Rats, Sprague-Dawley', 'Time Factors'] | 8,358,938 | [['B01.050'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['A02.835.232', 'A10.165.265'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['E05.799.513', 'G01.750.740', 'N06.850.810... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
CSF transplantation of a specific iPSC-derived neural stem cell subpopulation ameliorates the disease phenotype in a mouse model of spinal muscular atrophy with respiratory distress type 1. | Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a genetic motor neuron disease affecting infants. This condition is caused by mutations in the IGHMBP2 gene and currently has no cure. Stem cell transplantation is a potential therapeutic strategy for motor neuron diseases such as SMARD1, exerting ben... | ['Animals', 'Disease Models, Animal', 'Humans', 'Induced Pluripotent Stem Cells', 'Mice', 'Muscular Atrophy, Spinal', 'Neural Stem Cells', 'Phenotype', 'Respiratory Distress Syndrome, Newborn', 'Stem Cell Transplantation'] | 31,445,043 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['C10.228.854.468', 'C10.574.562.500', 'C10.668.467.500'], ['A11.872.653'], ['G05.695'], ['C08.381.840.500', 'C08.618.840.500... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral continuous positive airway pressure (CPAP) following nasal injury in a preterm infant. | Non-invasive respiratory support is increasingly popular but is associated with complications including nasal trauma. The present report describes a novel method of oral continuous positive airway pressure (CPAP) delivery in an extremely premature infant with severe nasal septum erosion. The distal end of a cut down en... | ['Continuous Positive Airway Pressure', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Nasal Septum', 'Positive-Pressure Respiration', 'Respiratory Distress Syndrome, Newborn'] | 20,231,219 | [['E02.041.625.790.259', 'E02.880.820.790.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['A04.531.591'], ['E02.041.625.790', 'E02.880.820.790'], ['C08.381.840.500', 'C08.618.840.500', 'C16.614.521.563']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Landmark-based morphometrics of the normal adult brain using MRI. | We describe the application of statistical shape analysis to homologous landmarks on the cortical surface of the adult human brain. Statistical shape analysis has a sound theoretical basis. Landmarks are identified on the surface of a 3-D reconstruction of the segmented cortical surface from magnetic resonance image (M... | ['Adolescent', 'Adult', 'Brain Mapping', 'Cephalometry', 'Cerebral Cortex', 'Dominance, Cerebral', 'Female', 'Frontal Lobe', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Male', 'Mathematical Computing', 'Middle Aged', 'Reference Values'] | 11,304,077 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A08.186.211.200.885.287.500'], ['F02.830.297', 'G11.561.225'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effects of rosiglitazone on proliferation and differentiation of duck preadipocytes. | Rosiglitazone (RSG), one member of the thiazolidinediones (TZDs), is a type of anti-diabetic drug in diabetic humans and animal models, whose function remains unknown in waterfowl. In this study, effects of RSG on duck preadipocyte differentiation were investigated. We detected cell viability using CCK method and measu... | ['Adipocytes', 'Adipogenesis', 'Animals', 'Cell Differentiation', 'Cell Proliferation', 'Ducks', 'Fatty Acids, Nonesterified', 'Humans', 'Lipogenesis', 'Lipolysis', 'Rosiglitazone', 'Thiazolidinediones'] | 26,487,429 | [['A11.329.114'], ['G04.152.149'], ['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['D10.251.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.528', 'G03.458.249'], ['G02.111.534', 'G03.458.500'], ['D02.886.675.933.500', '... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Survival of phage M13 with uracils on one or both DNA strands. | The survival of M13 DNA was studied after partial replacement of thymine by uracil in the bacteriophage. Uracils carry the same genetic information as the thymines. Nevertheless in Escherichia coli wild-type cells, uracils in DNA are replaced by thymines by excision repair initiated by uracil-DNA glycosylase (UDG). Thu... | ['Base Sequence', 'Coliphages', 'DNA Damage', 'DNA Repair', 'DNA, Single-Stranded', 'DNA, Viral', 'Electrophoresis', 'Escherichia coli', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Transformation, Bacterial', 'Uracil Nucleotides'] | 1,620,092 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.123.205'], ['G05.200'], ['G02.111.222', 'G05.219'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D13.444.308.568'], ['E05.196.401', 'E05.301.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['L01.453.245.667'], ['D13... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Diagnosis of gallbladder dyskinesia by quantitative hepatobiliary scintigraphy. | AIM: The aim of the present study was to develop a new pharmacologic method during hepatobiliary scintigraphy by which patients with functional and organic forms of gallbladder (GB) dysfunction can be differentiated.METHODS: Quantitative hepatobiliary scintigraphy (QHBS) was performed on 31 patients with impaired GB mo... | ['Biliary Dyskinesia', 'Biliary Tract', 'Ceruletide', 'Female', 'Gallbladder', 'Humans', 'Image Interpretation, Computer-Assisted', 'Liver', 'Male', 'Middle Aged', 'Nitroglycerin', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Technetium Tc 99m Diethyl-imi... | 15,827,396 | [['C06.130.120.250.098'], ['A03.159'], ['D12.644.456.241'], ['A03.159.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A03.620'], ['M01.060.116.630'], ['D02.640.636'], ['E01.370.350.710', 'E01.370.384.730'], ['D27.505.259.843', 'D27.505.519.871... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Real-time measurement of flow rate in microfluidic devices using a cantilever-based optofluidic sensor. | Real-time and accurate measurement of flow rate is an important reqirement in lab on a chip (LOC) and micro total analysis system (ìTAS) applications. In this paper, we present an experimental and numerical investigation of a cantilever-based optofluidic flow sensor for this purpose. Two sensors with thin and thick can... | ['Elastic Modulus', 'Microfluidic Analytical Techniques', 'Optical Phenomena', 'Time Factors'] | 24,291,805 | [['G01.374.590.605'], ['E05.588.465'], ['G01.590'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Getting our own house in order: improving psychiatry education to medical students as a prelude to medical school education reform. | OBJECTIVE: The authors summarize efforts to revitalize psychiatry teaching to medical students at Harvard Medical School (HMS) in advance of a major overhaul of the medical school curriculum.METHODS: This preliminary report chronicles key challenges and the organization of the reform effort within the departments of ps... | ['Education, Medical', 'Humans', 'Psychiatry', 'Social Change', 'United States'] | 16,609,125 | [['I02.358.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.544', 'H02.403.690'], ['I01.076.201.450.776', 'I01.880.853.400', 'N01.824.737'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Clinical impact of intravascular ultrasound guidance in drug-eluting stent implantation for unprotected left main coronary disease: pooled analysis at the patient-level of 4 registries. | OBJECTIVES: This study sought to investigate the clinical impact of the use of intravascular ultrasound (IVUS) during revascularization of patients with left main coronary artery (LM) disease with drug-eluting stents (DES).BACKGROUND: Whether the use of IVUS during the procedure adds a clinical benefit remains unclear.... | ['Aged', 'Blood Vessel Prosthesis Implantation', 'Coronary Artery Disease', 'Drug-Eluting Stents', 'Female', 'Humans', 'Male', 'Myocardial Revascularization', 'Postoperative Complications', 'Propensity Score', 'Registries', 'Spain', 'Surgery, Computer-Assisted', 'Survival Rate', 'Ultrasonography, Interventional'] | 24,650,399 | [['M01.060.116.100'], ['E04.100.814.868.500', 'E04.650.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E07.695.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.100.376.719', 'E04.928.220.520'], ['C23.550.767'], ['E05.318.740.600.675', 'N05.715.360.750.625.620', 'N06.850.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Senile chorea treated by deep brain stimulation: a clinical, neurophysiological and functional imaging study. | We report on a patient with senile chorea, treated with deep brain stimulation of the left globus pallidus internus and subsequently the left ventralis oralis posterior nucleus of the thalamus. Deep brain field potential recordings and functional imaging using single photon emission tomography enabled us to suggest pat... | ['Aged', 'Brain', 'Chorea', 'Electric Stimulation', 'Electrodes, Implanted', 'Electromyography', 'Evoked Potentials', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Muscle, Skeletal', 'Severity of Illness Index', 'Tomography, Emission-Computed, Single-Photon'] | 15,133,831 | [['M01.060.116.100'], ['A08.186.211'], ['C10.228.662.262.249', 'C10.597.350.250', 'C23.888.592.350.250'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A02.6... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The input of the chemical potential gradient of the water in the medium to the energy balance of terrestrial vascular plants]. | One of the characteristic feature of activity of plant organism vital functions is a speed of its inner water flow. The main source of energy providing the transport of water is gradient of water chemical potential between soil and atmosphere. In case of equal potentials of these surroundings, the plant organism have a... | ['Atmosphere', 'Energy Metabolism', 'Helianthus', 'Plants', 'Seeds', 'Soil', 'Triticum', 'Water'] | 10,778,391 | [['G16.500.275.063', 'N06.230.300.100'], ['G03.295'], ['B01.650.940.800.575.912.250.100.400'], ['B01.650'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.940.800.575.912.250.822.918'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.65... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Benzimidazole-embedded N-fused aza-indacenes: synthesis and deprotonation-assisted optical detection of carbon dioxide. | N-fused aza-indacene-based fluorophores 1 and 2 were prepared via a three-component condensation involving benzimidazole-carbinol, trifluoroacetic acid, and either pyrrole or indole, respectively. The N-fused aza-indacenes act as optical-based chemosensors for dissolved carbon dioxide gas following fluoride anion-media... | ['Aza Compounds', 'Benzimidazoles', 'Carbon Dioxide', 'Models, Molecular', 'Molecular Structure', 'Optical Phenomena', 'Protons'] | 23,811,989 | [['D02.145'], ['D03.633.100.103'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G01.590'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Life events, psychosocial factors, and demographic variables in early rheumatoid arthritis: relations to one-year changes in functional disability. | OBJECTIVE: To explore how life events, psychosocial factors, and demographic variables are related to one-year changes in disability in early rheumatoid arthritis (RA).METHODS: A sample of 238 patients with RA of 48 mo duration or less was examined at baseline and after 12 mo (n = 227; 95%). Data on life events and psy... | ['Adult', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Arthritis, Rheumatoid', 'Demography', 'Disability Evaluation', 'Female', 'Follow-Up Studies', 'Health Status', 'Humans', 'Life Change Events', 'Male', 'Middle Aged', 'Risk Factors', 'Socioeconomic Factors', 'Surveys and Questionnaires'] | 8,835,552 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E01.370.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
High-dose dexamethasone therapy in chronic idiopathic thrombocytopenic purpura. | A high-dose pulse of dexamethasone has been described as a current option for the treatment of refractory idiopathic thrombocytopenic purpura (ITP), but the results are controversial. Here we describe the use of a high does of dexamethasone (40 mg per day for 4 days every month) in 18 patients with chronic ITP. The med... | ['Adolescent', 'Adult', 'Dexamethasone', 'Dose-Response Relationship, Drug', 'Female', 'Glucocorticoids', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Purpura, Thrombocytopenic, Idiopathic', 'Splenectomy'] | 8,890,705 | [['M01.060.057'], ['M01.060.116'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G07.690.773.875', 'G07.690.936.500'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['M01.060.116.630'], ['C15.378.100.802.687.600', 'C15.378.140.855.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Masticatory jaw movement of Exaeretodon argentinus (Therapsida: Cynodontia) inferred from its dental microwear. | Dental microwear of four postcanine teeth of Exaeretodon argentinus was analyzed using both two dimensional (2D) and three dimensional (3D) methods to infer their masticatory jaw movements. Results of both methods were congruent, showing that linear microwear features (scratches) were well aligned and mostly directed t... | ['Animals', 'Fishes', 'Fossils', 'Jaw', 'Mastication', 'Tooth Wear'] | 29,186,178 | [['B01.050'], ['B01.050.150.900.493'], ['I01.076.368.584.311'], ['A02.835.232.781.324.502', 'A14.521'], ['G07.203.650.283.500', 'G10.261.330.500'], ['C07.793.818']] | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
The Role of the NICU in Father Involvement, Beliefs, and Confidence: A Follow-up Qualitative Study. | BACKGROUND: Fathers are important to infant outcomes. Infants of involved fathers have improved weight gain, sleep, and psychosocial behaviors. Father involvement with neonatal intensive care unit (NICU) infants reduces the length of stay.PURPOSE: The purpose of this study was to explore and describe involvement, confi... | ['Adult', 'Curriculum', 'Education, Nursing, Continuing', 'Father-Child Relations', 'Fathers', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Intensive Care Units, Neonatal', 'Male', 'Middle Aged'] | 31,567,277 | [['M01.060.116'], ['I02.158'], ['I02.358.212.450', 'I02.358.462.399'], ['F01.829.263.370.290.110'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Gross morphological and ultrastructural characterization of the oropharyngeal cavity of the Eurasian hoopoe captured from Egypt. | The present study aimed to give full morphological insight into the oropharyngeal cavity of Eurasian hoopoe at the level of gross morphology in addition to ultrastructural inspection including light- and scanning electron microscopy. The oropharyngeal cavity has a triangular appearance with a very long rostrally locate... | ['Animals', 'Birds', 'Egypt', 'Microscopy, Electron, Scanning', 'Oropharynx'] | 30,357,609 | [['B01.050'], ['B01.050.150.900.248'], ['Z01.058.266.317'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A04.623.603', 'A14.724.603']] | ['Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models. | BACKGROUND: Modern resuscitation strategies following haemorrhagic shock are influenced by global haemodynamic parameters such as blood pressure and cardiac output. Microcirculatory dysfunction in this context may persist even after restoration of satisfactory global parameters. Additional monitoring of the microcircul... | ['Animals', 'Fluid Therapy', 'Microcirculation', 'Models, Animal', 'Research Design', 'Resuscitation', 'Shock, Hemorrhagic', 'Systematic Reviews as Topic'] | 26,437,713 | [['B01.050'], ['E02.319.360'], ['G09.330.100.645'], ['E05.598'], ['E05.581.500', 'H01.770.644.728'], ['E02.365.647'], ['C23.550.414.980', 'C23.550.835.650'], ['L01.178.682.759.575']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Impact strength of acrylic resin denture base materials with surface defects. | The first part of this study involved the development of a method for evaluating the effect of small surface defects (3.0 microns-80.0 microns) on the impact strength of acrylic denture base materials. The method was used to compare the properties of 12 denture base materials, some of which are described as "high-impac... | ['Acrylic Resins', 'Analysis of Variance', 'Dental Stress Analysis', 'Denture Bases', 'Hardness', 'Materials Testing', 'Pliability', 'Reproducibility of Results', 'Surface Properties'] | 7,988,767 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E06.308'], ['E06.780.346.760.281', 'E07.695.190.200.200'], ['G01.374.647'], ['E05.570'], ['G01.374.705'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.85... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Lower gastrointestinal disorders in patients with irritable bowel syndrome. | Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal system characterized by abdominal pain related to bowel emptying, defecation impairment and abdominal distention. The aim of the study was to objectify lower gastrointestinal system disturbances in IBS patients. Thirty IBS patients and 30 h... | ['Adult', 'Female', 'Gastrointestinal Diseases', 'Gastrointestinal Motility', 'Humans', 'Irritable Bowel Syndrome', 'Lower Gastrointestinal Tract', 'Male', 'Manometry'] | 18,982,748 | [['M01.060.116'], ['C06.405'], ['G10.261.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.158.272.608'], ['A03.556.249'], ['E05.559']] | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Increased transaminase activity in the patients and personnel of dialysis centers and problem of its assessment]. | Within the general hepatitis prevention on dialysis wards regular controls of the liver values and the HBsAG/AK are necessary for the patients and the personnel. The general symptom which is frequently found in these cases -- increased transaminase -- demands a diagnostic clarification and the exclusion of an acute vir... | ['Alanine Transaminase', 'Alkaline Phosphatase', 'Bilirubin', 'Clinical Enzyme Tests', 'Diagnosis, Differential', 'Enzyme Activation', 'Hepatitis A', 'Hepatitis B Surface Antigens', 'Humans', 'Renal Dialysis', 'Thymol', 'Transaminases'] | 506,494 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia. | Childhood Acute Myeloid Leukemia (AML) is a clinically and genetically heterogeneous malignant disease. Despite improvements in outcome over the past decades, the current survival rate still is approximately 60-70%. Cytogenetic, recurrent genetic abnormalities and early response to induction treatment are the main fact... | ['Base Sequence', 'Biomarkers, Tumor', 'Gene Expression Profiling', 'Hedgehog Proteins', 'Humans', 'Leukemia, Myeloid, Acute', 'Molecular Sequence Data', 'Oncogene Proteins, Fusion', 'RNA, Messenger', 'Survival Analysis', 'Transcriptome', 'ras Proteins'] | 24,127,550 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D23.101.140'], ['E05.393.332'], ['D12.644.276.671', 'D12.776.467.671', 'D23.529.671'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['L01.453.245.667'], ['D12.776.602.500.500', 'D12.776.624.664.500'], ['D13.444.735.544'], ['E05.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Twin Legacies: Victor and Vincent McKusick/Twin Studies: Twinning Rates I; Twinning Rates II; MZ Twin Discordance for Russell-Silver Syndrome; Twins' Language Skills/Headlines: Babies Born to Identical Twin Couples; Identity Exchange; Death of Princess Ashraf (Twin); Yahoo CEO Delivers Identical Twins. | The lives of the illustrious monozygotic (MZ) twins, Victor A. and Vincent L. McKusick, are described. Victor earned the distinction as the 'Father of Medical Genetics', while Vincent was a legendary Chief Justice of the Maine Supreme Court. This dual biographical account is followed by two timely reports of twinning r... | ['Female', 'History, 21st Century', 'Humans', 'Language', 'Male', 'Twins, Dizygotic', 'Twins, Monozygotic'] | 26,934,824 | [['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['M01.438.873.920'], ['M01.438.873.940']] | ['Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Selective Removal of Malachite Green Dye from Aqueous Solutions by Supported Liquid Membrane Technology. | A lab-scale study on the application of supported liquid membranes (SLM) has been conducted for recovery and selective removal of Malachite Green dye from wastewater. Naturally occurring non-toxic vegetable oils have been used as membrane liquids. Polyvinylidene fluoride (PVDF) films have been used as supports for the ... | ['Environmental Restoration and Remediation', 'Hydrogen-Ion Concentration', 'Membranes, Artificial', 'Rosaniline Dyes', 'Solutions', 'Waste Water', 'Water Pollutants, Chemical', 'Water Purification'] | 31,546,761 | [['N06.230.080.600', 'N06.850.460.375'], ['G02.300'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D02.092.146.755'], ['D26.776'], ['D20.944.932', 'N06.850.460.710.865'], ['D27.888.284.903.655'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Fast and accurate method to purify small noncoding RNAs from Drosophila ovaries. | The recent development of High Throughput Sequencing technology has boosted the study of small regulatory RNA populations. A critical step prior to cloning and sequencing is purification of small RNA populations. Here, we report the optimization of an anion-exchange chromatography procedure in order to purify small reg... | ['Animals', 'Base Sequence', 'Chromatography, Ion Exchange', 'Dissection', 'Drosophila melanogaster', 'Female', 'Gene Silencing', 'Ovary', 'RNA, Small Interfering', 'Time Factors'] | 24,178,565 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.383'], ['E01.370.225.998.221', 'E04.221', 'E05.200.998.221'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.308.203.374'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['D13.150.650.700', 'D13.444.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Improvement in speech production following use of the UCH/RNID cochlear implant. | It has been noted that the speech of adults who become deaf can deteriorate, particularly in terms of suprasegmental features. The speech production skills of 30 post-lingually deafened adults who had derived no benefit from hearing aids was assessed before and after cochlear implantation using subjective and objective... | ['Cochlear Implants', 'Deafness', 'Humans', 'Speech', 'Speech Production Measurement'] | 2,607,195 | [['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['E01.370.760']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Neuromotor dyskinesia occurring during repeated injections of enkephalins into the rat striatum]. | The effect of 3-week daily injection of 5 or 15 mg enkephalin-like tetrapeptides (TP) into the rostral neostriatum was studied in chronic experiments on rats with implanted microcannulas. According to the type of TP, hyperkinesia or a pathological cataleptic status was registered in disorder of conditioned reflex behav... | ['Animals', 'Corpus Striatum', 'Dyskinesia, Drug-Induced', 'Enkephalins', 'Male', 'Rats', 'Rats, Inbred Strains'] | 1,818,278 | [['B01.050'], ['A08.186.211.200.885.287.249.487'], ['C10.228.662.262.500', 'C10.597.350.275', 'C10.720.312', 'C23.888.592.350.275', 'C25.100.750', 'C25.723.705.200'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain metastasis as the site of relapse in germ cell tumor of testis. | BACKGROUND: Brain metastases occur in approximately 8-15% of patients with testicular germ cell tumors and invariably are associated with relapse at other sites, most commonly the lungs, or as a terminal event.METHODS: The authors, from the Institute Rotary Cancer Hospital, a regional cancer center in northern India, d... | ['Adult', 'Aged', 'Brain Neoplasms', 'Dysgerminoma', 'Humans', 'Male', 'Neoplasms, Germ Cell and Embryonal', 'Recurrence', 'Testicular Neoplasms'] | 8,397,061 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.465.330.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465'], ['C23.550.291.937'], ['C04.588.322.762', 'C04.588.945.440.915', 'C12.294.260.937', 'C12.758.409.937', 'C19.344.762', 'C19.391.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of lapatinib on oral digoxin absorption in patients. | The potential for an interaction between lapatinib and absorption of the P-glycoprotein (ABCB1) substrate digoxin at a therapeutic dose in breast cancer patients was characterized. Seventeen women with HER2-positive metastatic breast cancer received a single oral 0.5-mg dose of digoxin on days 1 and 9 and oral lapatini... | ['ATP Binding Cassette Transporter, Subfamily B', 'Administration, Oral', 'Adult', 'Alberta', 'Antineoplastic Agents', 'Area Under Curve', 'Breast Neoplasms', 'Cardiotonic Agents', 'Cross-Over Studies', 'Digoxin', 'Drug Interactions', 'Female', 'Gastrointestinal Absorption', 'Half-Life', 'Humans', 'Lapatinib', 'Metabol... | 27,137,717 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['E02.319.267.100'], ['M01.060.116'], ['Z01.107.567.176.064'], ['D27.505.954.248'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Atrioventricular block disclosing an isolated congenital aneurysm of the sinus of Valsalva, extending into the septum and not ruptured]. | A case of a congenital aneurysm of the right anterior sinus of Valsalva (ASV) extending into the septum is reported. The patient, a 20 year old male Central-African, presented with syncopal complete atrioventricular block (AVB) or recent onset. There were no clinical or radiological signs of associated cardiac disease.... | ['Adult', 'Aortic Aneurysm', 'Echocardiography', 'Heart Block', 'Heart Septum', 'Humans', 'Male', 'Sinus of Valsalva'] | 6,796,027 | [['M01.060.116'], ['C14.907.055.239', 'C14.907.109.139'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['A07.541.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.056.847']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of therapeutic outcome: some reflections on methodology. | Problems connected with choice of outcome-criteria are discussed. Some results from an outcome study of student-conducted dynamic psychotherapies are presented. The discussion is focused on discrepancies between subjective data and more objective measures, as reflected in Rorschach test results. It is claimed that in o... | ['Adult', 'Ego', 'Fantasy', 'Female', 'Follow-Up Studies', 'Humans', 'Personality Development', 'Personality Disorders', 'Psychoanalytic Therapy', 'Psychophysiologic Disorders'] | 3,628,679 | [['M01.060.116'], ['F01.752.747.189', 'F02.739.794.206'], ['F01.393.351', 'F02.463.188.634.507'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747'], ['F03.675'], ['F04.754.709'], ['C23.888.592.700']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improved understanding of human anatomy through self-guided radiological anatomy modules. | RATIONALE AND OBJECTIVE: To quantifiably measure the impact of self-instructed radiological anatomy modules on anatomy comprehension, demonstrated by radiology, gross, and written exams.MATERIALS AND METHODS: Study guides for independent use that emphasized structural relationships were created for use with two online ... | ['Adult', 'Anatomy', 'Computer-Assisted Instruction', 'Education, Medical, Undergraduate', 'Educational Measurement', 'Female', 'Humans', 'Male', 'Radiology', 'Software', 'Young Adult'] | 22,537,504 | [['M01.060.116'], ['H01.158.100'], ['I02.903.771.500.208'], ['I02.358.399.450'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.740'], ['L01.224.900'], ['M01.060.116.815']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 |
Risk factors for recurrence following radical cystectomy for pathologic node negative bladder cancer. | BACKGROUND AND OBJECTIVES: To evaluate for risk factors associated with bladder cancer recurrence in patients with pathologically negative lymph nodes.METHODS: A retrospective review of 405 patients undergoing radical cystectomy for bladder cancer between 1996 and 2008 was performed. Patients with node-positive disease... | ['Aged', 'Cystectomy', 'Female', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Retrospective Studies', 'Risk Factors', 'Urinary Bladder Neoplasms'] | 20,607,757 | [['M01.060.116.100'], ['E04.950.774.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E01.789.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.36... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Microwave energy as a precoagulative device to assist in hepatic resection. | INTRODUCTION: Microwave energy is another energy source than can be used to precoagulate hepatic tissue during hepatic resection. The aim of this study was to develop an optimal microwave precoagulation technique in a porcine model and then validate the technique during hepatic resection in patients.METHODS: Institutio... | ['Ablation Techniques', 'Animals', 'Electrocoagulation', 'Hemostasis', 'Hepatectomy', 'Humans', 'Laparoscopy', 'Liver', 'Microwaves', 'Models, Animal', 'Swine'] | 19,727,958 | [['E04.014'], ['B01.050'], ['E02.154.402', 'E04.014.170.402'], ['G09.188.390'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['A03.620'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['E05.598'], ['B01.050.150.900.649.313.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A randomized controlled trial investigation of a non-stimulant in attention deficit hyperactivity disorder (ACTION): rationale and design. | BACKGROUND: The ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized cross-over trial of the non-stimulant medication, Atomoxetine, in children and adolescents with attention deficit hyperactivity disorder (ADHD). The prima... | ['Adolescent', 'Adrenergic Uptake Inhibitors', 'Affect', 'Anxiety', 'Atomoxetine Hydrochloride', 'Attention Deficit Disorder with Hyperactivity', 'Australia', 'Child', 'Cognition', 'Comorbidity', 'Cross-Over Studies', 'Double-Blind Method', 'Humans', 'Logistic Models', 'Neuropsychological Tests', 'Propylamines', 'Psych... | 21,396,130 | [['M01.060.057'], ['D27.505.519.562.437.050', 'D27.505.519.625.050.601', 'D27.505.519.625.600.050', 'D27.505.696.577.050.601', 'D27.505.696.577.600.050'], ['F01.470.047'], ['F01.470.132'], ['D02.092.831.085'], ['F03.625.094.150'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['F02.463.188'], ['N05.715.350.225',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[Rifampicin (benemycin) treatment of salmonellosis in nursing infants]. | The efficacy of rifampicin (benemycin) in combined therapy of salmonellosis in 145 infants, including 25 newborns was studied. The data indicated that it was highly effective and superior to the other drugs, such as levomycetin, polymyxin, ampicillin and furazolidone, widely used at present for the treatment of salmone... | ['Drug Evaluation', 'Drug Resistance, Microbial', 'Humans', 'Infant', 'Infant, Newborn', 'Rifampin', 'Salmonella Infections', 'Salmonella typhimurium', 'Time Factors'] | 7,027,920 | [['E05.290.625', 'E05.337.425'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D03.633.400.811.700', 'D04.345.295.750.700'], ['C01.150.252.400.310.821'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antigen handling in ageing. III. Age-related changes in antigen handling by liver parenchymal and nonparenchymal cells. | This is a continuation of our earlier studies on antigen handling and the ageing process which have shown the liver to be a major site of antigen retention in the body. This paper reports on the uptake and cellular distribution in relatively pure isolates of the principal cell types of the liver of [35S]sulfanilate-azo... | ['Aging', 'Animals', 'Antigens', 'Endothelium', 'In Vitro Techniques', 'Kupffer Cells', 'Liver', 'Lymphocyte Activation', 'Male', 'Nucleoproteins', 'Peptides', 'Rats', 'Rats, Inbred F344'] | 6,482,526 | [['G07.345.124'], ['B01.050'], ['D23.050'], ['A10.272.491'], ['E05.481'], ['A11.329.372.588', 'A11.627.482.588', 'A11.733.397.588', 'A15.382.670.522.588', 'A15.382.680.397.588'], ['A03.620'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['D12.776.664'], ['D12.644'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stat3-Atg5 signal axis inducing autophagy to alleviate hepatic ischemia-reperfusion injury. | In performing our experiment, impaired autophagy increased hepatocellular damage during the reperfusion period. It was demonstrated by the effect of blocking autophagy using bafilomycin A1 or knocking Atg5 gene out reduces the anti-apoptotic effect of Stat3. Here we focus on the role of signal transducer and activator ... | ['Animals', 'Apoptosis', 'Autophagy', 'Autophagy-Related Protein 5', 'Blotting, Western', 'Cell Line', 'Cell Survival', 'Disease Models, Animal', 'Immunohistochemistry', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Microscopy, Confocal', 'Microscopy, Electron, Transmission', 'Reperfusion Injury', 'STAT3 Transcriptio... | 29,143,976 | [['B01.050'], ['G04.146.954.035'], ['G04.011'], ['D12.776.094.250'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['G04.346'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-inferiority of insulin glargine versus insulin detemir on blood glucose variability in type 1 diabetes patients: a multicenter, randomized, crossover study. | BACKGROUND: This study compared the effects of insulin glargine and insulin detemir on blood glucose variability under clinical practice conditions in patients with type 1 diabetes (T1D) using glulisine as the mealtime insulin.METHODS: This was a multicenter, crossover trial in 88 randomized T1D patients: 54 men and 34... | ['Adult', 'Blood Glucose', 'Cross-Over Studies', 'Diabetes Mellitus, Type 1', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemic Agents', 'Insulin Detemir', 'Insulin Glargine', 'Insulin, Long-Acting', 'Male', 'Middle Aged'] | 21,810,024 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Determination of 16 PAHs and 22 PCBs in honey samples originated from different region of Lebanon and used as environmental biomonitors sentinel. | In order to assess the air quality in some Lebanese regions, a biomonitoring study based on honey as biomonitor candidate was conducted. For this, 18 samples of honey collected from four regions in Lebanon, were analyzed for their contamination by 16 polycyclic aromatic hydrocarbons (PAHs) and 22 polychlorinated biphen... | ['Air Pollution', 'Animals', 'Bees', 'Environmental Monitoring', 'Gas Chromatography-Mass Spectrometry', 'Honey', 'Lebanon', 'Polychlorinated Biphenyls', 'Polycyclic Aromatic Hydrocarbons', 'Sentinel Surveillance', 'Solid Phase Microextraction', 'Tandem Mass Spectrometry'] | 30,199,354 | [['N06.850.460.100'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G07.203.300.581', 'J02.500.581'], ['Z01.252.245.500.450'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['D02.455.426.559.84... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Virus replication in enucleate cells: vesicular stomatitis virus and influenza virus. | The requirement of the presence of a nucleus for the replication of vesicular stomatitis virus and influenza virus has been examined by following the growth and development of these viruses in enucleate BS-C-1 cells. Vesicular stomatitis virus replicates normally in enucleate cells with the rate of production of infect... | ['Animals', 'Autoradiography', 'Carbon Radioisotopes', 'Cell Line', 'Cell Nucleus', 'Cells, Cultured', 'Cytochalasin B', 'Electrophoresis, Polyacrylamide Gel', 'Haplorhini', 'Influenza A virus', 'Kidney', 'Orthomyxoviridae', 'Peptide Biosynthesis', 'RNA, Viral', 'Sulfur Radioisotopes', 'Tritium', 'Vesicular stomatitis ... | 4,359,299 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['D03.633.100.473.231.370', 'D23.946.587.370.370'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Passion, countertransference enactment, and breakdown in the psychoanalysis of a young woman. | Transference-countertransference involvement with patients the analyst finds "pleasurable" is examined. Analysis of such patients courts the danger that pathological identifications will go unrecognized and the analysis end at a point where the opportunity for decisive change, which to the patient appears physically an... | ['Adult', 'Countertransference', 'Female', 'Humans', 'Love', 'Professional-Patient Relations', 'Psychoanalytic Therapy', 'Psychophysiologic Disorders', 'Treatment Outcome'] | 11,059,398 | [['M01.060.116'], ['F04.754.720.864.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.734'], ['F01.829.401.650', 'N05.300.660'], ['F04.754.709'], ['C23.888.592.700'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An integrated phylogenetic analysis on ascaridoid nematodes (Anisakidae, Raphidascarididae), including further description and intraspecific variations of Raphidascaris (Sprentascaris) lanfrediae in freshwater fishes from Brazil. | Genetic and morphological variations in two component populations of Raphidascaris (Sprentascaris) lanfrediae collected in the intestine of Geophagus argyrosticus and G. proximus (Cichlidae) from States of Par? and Amap?, Brazil, respectively, were explored for the first time. A phylogenetic study including two genes (... | ['Animals', 'Ascaridida Infections', 'Ascaridoidea', 'Brazil', 'Fish Diseases', 'Fishes', 'Genetic Variation', 'Microscopy, Confocal', 'Phylogeny', 'Polymerase Chain Reaction', 'RNA, Ribosomal, 18S', 'Sequence Analysis, DNA'] | 27,771,461 | [['B01.050'], ['C01.610.335.508.700.100'], ['B01.050.500.500.294.400.500.100'], ['Z01.107.757.176'], ['C22.362'], ['B01.050.150.900.493'], ['G05.365'], ['E01.370.350.515.395', 'E05.595.395'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500'], ['D13.444.735.686.675'], ['E05.393.760.700']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Association of the TaqI A polymorphism of the dopamine D(2) receptor gene with predisposition to neuroleptic malignant syndrome. | OBJECTIVE: The pathophysiology of neuroleptic malignant syndrome is mainly explained by a central hypodopaminergic state. The familial occurrence of neuroleptic malignant syndrome suggests the involvement of a genetic mechanism in the predisposition to the syndrome. Therefore, the authors examined the association betwe... | ['Adult', 'Antipsychotic Agents', 'Depressive Disorder', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Neuroleptic Malignant Syndrome', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length', 'Receptors, Dopamine D2', 'Schizoph... | 11,579,007 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F03.600.300'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.737', 'C10.720.737', 'C25.723.705.600'], ['E05.393.620.500'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia. | Functional defects of the mitochondrial translation machinery, as a result of mutations in nuclear-encoded genes, have been associated with combined oxidative phosphorylation (OXPHOS) deficiencies. We report siblings with congenital sensorineural deafness and lactic acidemia in association with combined respiratory cha... | ['Acidosis, Lactic', 'Adolescent', 'Base Sequence', 'Child', 'Child, Preschool', 'Disease Progression', 'Female', 'Hearing Loss, Sensorineural', 'Humans', 'Infant', 'Liver Failure', 'Mitochondria', 'Mitochondrial Proteins', 'Molecular Sequence Data', 'Mutation', 'Protein Biosynthesis', 'Renal Insufficiency', 'Ribosomal... | 25,556,185 | [['C18.452.076.176.180'], ['M01.060.057'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.656'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C06.552.... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
CRISPR/Cas9-mediated genome editing reveals differences in the contribution of INDEHISCENT homologues to pod shatter resistance in Brassica napus L. | The INDEHISCENT (IND) and ALCATRAZ (ALC) gene homologues have been reported to be essential for dehiscence of fruits in Brassica species. But their functions for pod shatter resistance in Brassica napus, an important oil crops, are not well understood. Here, we assessed the functions of these two genes in rapeseed usin... | ['Alleles', 'Basic Helix-Loop-Helix Transcription Factors', 'Brassica napus', 'CRISPR-Cas Systems', 'Gene Editing', 'Gene Knockout Techniques', 'Genes, Plant', 'Phenotype', 'Plant Proteins', 'Plants, Genetically Modified', 'Seeds'] | 30,980,103 | [['G05.360.340.024.340.030'], ['D12.776.260.103', 'D12.776.930.125'], ['B01.650.940.800.575.912.250.157.200.249'], ['G05.308.203.374.394'], ['E05.393.420.270'], ['E05.393.335.750'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.695'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['A18.024.500.750', 'G07... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
On the synthesis of Z-gamma-amino-alpha,beta-unsaturated esters via Ru-catalyzed coupling. | [formula: see text] A synthesis of gamma-amino acids and their cyclic derivatives, 3-pyrrolinones, from alpha-amino acids employs a ruthenium-catalyzed Alder ene reaction as a key step in the sequence. Cyclopentadienylruthenium (1,4-cyclooctadiene) chloride catalyzes the addition of gamma-amido-alpha,beta-alkynoate est... | ['Alkenes', 'Alkynes', 'Amides', 'Catalysis', 'Cyclization', 'Esters', 'Oxidation-Reduction', 'Ruthenium', 'Tin'] | 10,822,535 | [['D02.455.326.271'], ['D02.455.326.397'], ['D02.065'], ['G02.130'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D02.241.400'], ['G02.700', 'G03.295.531'], ['D01.268.556.805', 'D01.268.956.812', 'D01.552.544.805'], ['D01.268.556.875', 'D01.552.544.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical spectrum and prognostic factors of possible UIP pattern on high-resolution CT in patients who underwent surgical lung biopsy. | BACKGROUND: Few studies have reported the diagnostic variability in patients with a possible usual interstitial pneumonia (UIP) pattern on high-resolution CT (HRCT) who underwent surgical lung biopsy (SLB), and the prognostic factors for these patients have not been fully evaluated. We retrospectively investigated the ... | ['Aged', 'Biopsy', 'Female', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Lung', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 29,590,152 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.765.500'], ['A04.411'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. | The cytokine B cell activating factor (BAFF) and its receptor, BAFF receptor (BAFF-R), modulate signaling cascades critical for B cell development and survival. We identified a novel mutation in TNFRSF13C, the gene encoding human BAFF-R, that is present in both tumor and germline tissue from a subset of patients with n... | ['Amino Acid Sequence', 'B-Cell Activation Factor Receptor', 'Cell Line', 'Humans', 'Immunoglobulins', 'Lymphoma, Non-Hodgkin', 'Molecular Sequence Data', 'Mutation', 'NF-kappa B', 'Signal Transduction', 'TNF Receptor-Associated Factor 3', 'TNF Receptor-Associated Factor 6'] | 21,041,452 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.543.750.705.852.760.222'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['L01.453.245.667'], ['G05.365.590... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of one-year treatment with isoflavone extract from red clover on prostate, liver function, sexual function, and quality of life in men with elevated PSA levels and negative prostate biopsy findings. | OBJECTIVES: To asses the effect of an isoflavonoid extract from red clover on the prostate, liver function, quality of life, and sexual function in men with an initial elevated prostate-specific antigen (PSA) level and negative prostate biopsy findings during a 1-year treatment period.METHODS: A total of 20 men (mean a... | ['Aged', 'Biopsy', 'Gonadal Steroid Hormones', 'Humans', 'Isoflavones', 'Liver', 'Male', 'Middle Aged', 'Penile Erection', 'Phytotherapy', 'Plant Extracts', 'Prospective Studies', 'Prostate', 'Prostate-Specific Antigen', 'Quality of Life', 'Time Factors', 'Trifolium'] | 18,308,079 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D06.472.334.851'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['A03.620'], ['M01.06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Importance of cytogenetic analysis in patients with azoospermia or severe oligozoospermia undergoing in vitro fertilization]. | The karyotypic analysis was performed to assess the importance of genetic factor in male infertility. For that purpose, chromosomal analysis in blood lymphocytes was performed in 28 males, candidates for ICSI with azoospermia or severe oligozoospermia and in their spouses. Although chromosomal aberrations were identifi... | ['Adult', 'Chromosome Aberrations', 'Chromosome Disorders', 'Female', 'Fertilization in Vitro', 'Humans', 'Karyotyping', 'Male', 'Mosaicism', 'Oligospermia', 'Poland', 'Risk Factors'] | 11,848,024 | [['M01.060.116'], ['C23.550.210', 'G05.365.590.175'], ['C16.131.260', 'C16.320.180'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['G05.365.590.175.595'], ['C12.294.365.700.508'], ['Z01... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Intrahepatic and peripheral blood virus-specific cytotoxic T lymphocyte activity is associated with a response to combination IFN-alpha and ribavirin treatment among patients with chronic hepatitis C virus infection. | This report describes an association between intrahepatic and peripheral blood cytotoxic T lymphocytes (CTL) activity present prior to receiving treatment, and a response to combination interferon-alpha (IFN-alpha) and ribavirin therapy for chronic hepatitis C virus (HCV) infection. Recombinant vaccinia virus construct... | ['Cohort Studies', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Immunohistochemistry', 'Interferon alpha-2', 'Interferon-alpha', 'Liver Function Tests', 'Lymphocyte Activation', 'Male', 'Probability', 'Prognosis', 'Prospect... | 15,720,526 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E02.319.310'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro and in vivo antifungal properties of cysteine proteinase inhibitor from green kiwifruit. | BACKGROUND: Higher plants possess several mechanisms of defense against plant pathogens. Proteins actively synthesized in response to those stresses are called defense-related proteins which, among others, include certain protease inhibitors. It is of particular relevance to investigate plant natural defense mechanisms... | ['Actinidia', 'Alternaria', 'Botrytis', 'Cysteine Proteinase Inhibitors', 'Fruit', 'Fungicides, Industrial', 'Plant Diseases', 'Spores, Fungal'] | 22,653,546 | [['B01.650.940.800.575.912.250.341.500.500'], ['B01.300.381.075'], ['B01.300.381.128'], ['D27.505.519.389.745.325'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D27.720.031.700.288', 'D27.888.723.288'], ['G15.610'], ['A11.870.710', 'A19.374.500', 'B05.775.710']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Vascular patients' preferences for local treatment: an application of conjoint analysis. | OBJECTIVES: To investigate whether and to what extent vascular patients are willing to trade expected health outcomes for improvements in non-health benefits, such as the availability of local services, in the provision of peripheral vascular surgery.METHODS: Conjoint analysis was used to elicit patient preferences via... | ['Community Health Services', 'Health Services Accessibility', 'Health Services Research', 'Humans', 'Patient Satisfaction', 'Peripheral Vascular Diseases', 'State Medicine', 'Surveys and Questionnaires', 'United Kingdom'] | 11,467,272 | [['N02.421.143'], ['N04.590.374.350', 'N05.300.430'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['C14.907.617'], ['N03.349.550.902', 'N03.858'], ['E05.31... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Expression, subcellular localization and putative function of platelet-type 12-lipoxygenase in human prostate cancer cell lines of different metastatic potential. | The involvement of 12-lipoxygenase (12-LOX) expression and function in tumor metastasis has been demonstrated in several murine tumor cell lines. In addition, 12-LOX expression was detected in human prostatic tumors and correlated to the clinical stage of disease. Here we provide data that human prostate cancer cell li... | ['Animals', 'Arachidonate 12-Lipoxygenase', 'Blood Platelets', 'Cell Membrane', 'Cytoplasm', 'Cytoskeleton', 'Disease Progression', 'Flow Cytometry', 'Humans', 'Immunohistochemistry', 'Lipoxygenase Inhibitors', 'Male', 'Mice', 'Mice, SCID', 'Microscopy, Confocal', 'Neoplasm Invasiveness', 'Neoplasm Transplantation', 'N... | 10,861,450 | [['B01.050'], ['D08.811.682.690.416.583.500.060', 'D12.776.556.579.374.568.500.025'], ['A11.118.188', 'A15.145.229.188'], ['A11.284.149'], ['A11.284.430.214'], ['A11.284.430.214.190.750'], ['C23.550.291.656'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
High IgM production by human-human hybridoma HB4C5 cells cultured in microtubes. | HB4C5 cells, a human-human hybridoma, were cultured in microtubes. After 24 h of cultivation, growth of the cells cultured in microtubes was 1.2- to 1.5-fold that in culture dishes or 96-well culture plates. The production of IgM was 2.6- to 3.3-fold that in the 96-well culture plates. | ['Cell Count', 'Cell Culture Techniques', 'Cells, Cultured', 'Culture Media', 'Humans', 'Hybridomas', 'Immunoglobulin M', 'Time Factors'] | 12,729,006 | [['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.353.485', 'A11.251.600.485'], ['D12.776.124.486.485.114.619.574', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anxiety, Anxiety Sensitivity, and Perceived Stress as Predictors of Recent Drinking, Alcohol Craving, and Social Stress Response in Heavy Drinkers. | BACKGROUND: Stress and anxiety are widely considered to be causally related to alcohol craving and consumption, as well as development and maintenance of alcohol use disorder (AUD). However, numerous preclinical and human studies examining effects of stress or anxiety on alcohol use and alcohol-related problems have be... | ['Adult', 'Alcohol Drinking', 'Alcohol-Induced Disorders', 'Anxiety', 'Craving', 'Female', 'Follow-Up Studies', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Perception', 'Stress, Psychological', 'Young Adult'] | 28,281,290 | [['M01.060.116'], ['F01.145.317.269'], ['C25.775.100.087'], ['F01.470.132'], ['F01.658.293.195'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['F02.463.593'], ['F01.145.126.990', 'F02.83... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bone marrow in leukemia and aplastic anemia: MR imaging before, during, and after treatment. | Serial magnetic resonance (MR) studies of the cervical bone marrow were performed in five patients undergoing bone marrow transplantation for chronic granulocytic leukemia and in four patients with aplastic anemia who were treated with antilymphocytic globulin. Findings were compared with those from a group of healthy ... | ['Adolescent', 'Adult', 'Anemia, Aplastic', 'Antilymphocyte Serum', 'Bone Marrow', 'Bone Marrow Transplantation', 'Female', 'Humans', 'Leukemia, Myeloid', 'Magnetic Resonance Spectroscopy', 'Male', 'Middle Aged'] | 3,544,034 | [['M01.060.057'], ['M01.060.116'], ['C15.378.071.085', 'C15.378.190.223.250'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['A15.382.216'], ['E02.095.147.725.040', 'E04.936.580.040'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predictors of weight change following smoking cessation. | Smoking behavior and weight change over a 5-year period were studied in 1,749 adult males of the Normative Aging Study. While men who quit smoking generally gained more weight than those in other smoking categories, 36% either lost weight or maintained the same weight after quitting. The major research focus was to pre... | ['Adult', 'Anxiety', 'Body Weight', 'Humans', 'Male', 'Middle Aged', 'Personality', 'Smoking'] | 7,450,953 | [['M01.060.116'], ['F01.470.132'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.752'], ['F01.145.805']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modulation of dopamine release in rat striatal slices by delta opiate agonists. | The effects of various opiates on the spontaneous release of [3H]dopamine ([3H]DA) continuously formed from [3H]tyrosine has been studied in rat striatal slices. Morphine (5 x 10(-6) M), fentanyl (5 x 10(-8) M) and the tripeptide Tyr-D-Ala-Gly-NH-CH(CH3)CH2-CH(CH3)2 (10(-6) M) were without effect, whereas D-Ala2-Met-en... | ['Animals', 'Corpus Striatum', 'Dopamine', 'Endorphins', 'Enkephalin, Methionine', 'Enkephalins', 'In Vitro Techniques', 'Male', 'Morphine', 'Naloxone', 'Narcotics', 'Rats', 'Rats, Inbred Strains', 'Receptors, Opioid', 'Receptors, Opioid, delta', 'Tetrodotoxin'] | 6,284,911 | [['B01.050'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['E05.481'], ['D03.132... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins. | The mRNA derived from influenza B virus RNA segment 6 is functionally bicistronic and encodes the NB and NA glycoproteins in different, overlapping reading frames. NB protein synthesis is initiated at the 5'-proximal AUG codon, and 4 nucleotides downstream there is a second AUG codon which is used to initiate NA protei... | ['Animals', 'Base Sequence', 'Cell Line', 'Chick Embryo', 'Chromosome Deletion', 'Codon', 'Gene Expression Regulation', 'Glycoproteins', 'Influenza B virus', 'Molecular Sequence Data', 'Mutation', 'Precipitin Tests', 'RNA, Messenger', 'RNA, Viral', 'Viral Proteins'] | 2,908,923 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['A13.350.150', 'A16.331.200'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['D13.444.735.544.355', 'G05.360.335.355', 'G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pharmacy and public health: a pathway forward. | OBJECTIVE To identify a pathway forward for practicing pharmacists in supporting public health initiatives by applying the five core competencies of public health. SUMMARY The pharmacist is well positioned to improve population health. Until now, increased impact of pharmacists has been based on the expansion of patien... | ['Clinical Competence', 'Humans', 'Pharmaceutical Services', 'Pharmacists', 'Professional Role', 'Public Health'] | 24,584,835 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.668'], ['M01.526.485.780', 'N02.360.780'], ['F01.829.316.616.625'], ['H02.403.720', 'N01.400.550', 'N06.850']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model. | Retinitis pigmentosa (RP) is characterized by progressive loss of vision due to photoreceptor degeneration leading to secondary inflammation. The urokinase-type plasminogen activator (uPA) system contributes to retinal inflammation, but its role in RP is unknown. In the rd10 mouse model of RP, we addressed this questio... | ['Animals', 'Disease Models, Animal', 'Humans', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Inflammation', 'Mice', 'Oligopeptides', 'Receptors, Urokinase Plasminogen Activator', 'Retina', 'Retinal Cone Photoreceptor Cells', 'Retinal Degeneration', 'Retinitis Pigmentosa', 'Urokinase-Type Plasminogen Activator'] | 31,251,468 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.456'], ['D12.776.395.550.448.813', 'D12.776.543.484.500.813', 'D12.776.543.550.418... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A valuable non-invasive diagnostic investigation for paediatric idiopathic brachial neuritis. | Idiopathic brachial neuritis (idiopathic neuralgic amyotrophy) in children is a well-recognized but rare condition. Although the precise aetiology is unknown, its usual occurrence after an infection suggests an immunological process. There is no specific test for brachial neuritis, and the diagnosis is one of exclusion... | ['Brachial Plexus Neuritis', 'Child, Preschool', 'Electromyography', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Neurologic Examination'] | 20,722,667 | [['C10.668.829.100.500', 'C10.668.829.650.250'], ['M01.060.406.448'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.376.550', 'E01.370.600.550']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Successful percutaneous treatment of gluteal claudication secondary to isolated bilateral hypogastric stenoses. | We report an unusual case of bilateral buttock claudication at ambulation of less than two blocks in a 57-year-old man with normal lower-extremity segmental pressure on noninvasive exercise testing. He was found to have bilateral high-grade internal iliac artery stenoses on arteriography. Both sides were successfully t... | ['Angioplasty, Balloon', 'Arterial Occlusive Diseases', 'Buttocks', 'Humans', 'Iliac Artery', 'Intermittent Claudication', 'Male', 'Middle Aged', 'Remission Induction', 'Stents'] | 16,414,405 | [['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137'], ['A01.378.610.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.444'], ['C14.907.137.126.669', 'C23.888.531'], ['M01.060.116.630'], ['E02.860'], ['E07.695.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Granulomatous angiitis of the central nervous system: protean manifestations and response to treatment. | Granulomatous angiitis is an uncommon necrotising vasculitis of unknown cause restricted to vessels of the central nervous system. Five tissue-proven cases emphasise the protean manifestations of this disease and the difficulties encountered in reaching a diagnosis. One patient presented with a temporoparietal mass, th... | ['Adult', 'Aged', 'Biopsy', 'Cerebral Arterial Diseases', 'Cerebral Arteries', 'Cerebral Infarction', 'Diabetic Angiopathies', 'Endothelium, Vascular', 'Granuloma', 'Humans', 'Male', 'Middle Aged', 'Polyarteritis Nodosa'] | 2,906,362 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C10.228.140.300.510.200', 'C14.907.253.560.200'], ['A07.015.114.228'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of weighted and composite scores for pre-clinical dental learners. | PURPOSE: The weighted mean (WM) method for combining scores of assessment components can provide outcomes with biased reliability and score precision. The objective of this study was to compare the traditional WM with another method utilising the composite score (CS) principle for combining scores of a final summative ... | ['Clinical Competence', 'Education, Dental', 'Educational Measurement', 'Esthetics, Dental', 'Humans', 'Reproducibility of Results', 'Students, Dental'] | 29,227,014 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.274'], ['I02.399'], ['E06.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['M01.848.769.519']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cost effectiveness of fracture prevention in postmenopausal women who receive aromatase inhibitors for early breast cancer. | PURPOSE: Aromatase inhibitors (AIs) increase the risk of osteoporosis and related fractures in postmenopausal women who receive adjuvant AIs for hormone receptor (HR) -positive early breast cancer (EBC). We compared the cost effectiveness of alternative screening and treatment strategies for fracture prevention.METHODS... | ['Absorptiometry, Photon', 'Administration, Oral', 'Age Factors', 'Aromatase Inhibitors', 'Bone Density', 'Bone Density Conservation Agents', 'Bone Diseases, Metabolic', 'Breast Neoplasms', 'Computer Simulation', 'Cost-Benefit Analysis', 'Diphosphonates', 'Disease-Free Survival', 'Drug Costs', 'Early Detection of Cance... | 22,370,313 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['E02.319.267.100'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['G11.427.100'], ['D27.505.696.242'], ['C05.116.198', 'C18.452.104'], ['C04.588.180', 'C17.800.090.500'], ['L01.224.160... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The disparity of frontline clinical staff and managers' perceptions of a quality and patient safety initiative. | RATIONALE, AIMS AND OBJECTIVES: Arguably, a shared perspective between managers and their clinical staff on an improvement initiative would allow for most effective implementation and increase programme success. However, it has been reported that research has failed to differentiate between managers and line employees ... | ['Attitude of Health Personnel', 'Cooperative Behavior', 'Health Personnel', 'Hospital Administrators', 'Humans', 'Organizational Culture', 'Patient Safety', 'Perception', 'Program Evaluation', 'Quality Improvement', 'Safety Management', 'Time Factors'] | 20,738,468 | [['F01.100.050', 'N05.300.100'], ['F01.145.813.115'], ['M01.526.485', 'N02.360'], ['M01.526.070.490.490', 'M01.526.485.430.490', 'M01.526.485.740.380', 'N02.360.430.490', 'N02.360.740.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.606'], ['N06.850.135.060.075.399'], ['F02.463.593'], ['E05.337.820', '... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Role for sulfur-containing groups in the Na+-Ca2+ exchange of cardiac sarcolemmal vesicles. | Different amino acid residues in cardiac sarcolemmal vesicles were modified by incubation with various chemical reagents. The effects of these modifications on sarcolemmal Na+-Ca2+ exchange were examined. Dithiothreitol, an agent that maintains sulfur-containing residues in a reduced state, caused a time- and concentra... | ['Animals', 'Carrier Proteins', 'Dithiothreitol', 'Dogs', 'Heart Ventricles', 'Kinetics', 'Myocardium', 'Sarcolemma', 'Sodium', 'Sodium-Calcium Exchanger', 'Sulfhydryl Compounds', 'Sulfhydryl Reagents'] | 3,560,203 | [['B01.050'], ['D12.776.157'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541.560'], ['G01.374.661', 'G02.111.490'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['A11.284.149.707'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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