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Geographic variation and trends in carotid imaging among medicare beneficiaries, 2001 to 2006. | BACKGROUND: Diagnostic imaging among Medicare beneficiaries is an important contributor to rising health care costs. We examined temporal trends and geographic variation in the use of carotid ultrasound, carotid magnetic resonance angiography (MRA), and carotid x-ray angiography.METHODS AND RESULTS: Analysis of a 5% na... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Carotid Arteries', 'Comorbidity', 'Coronary Angiography', 'Cost of Illness', 'Female', 'Humans', 'Magnetic Resonance Angiography', 'Male', 'Mid-Atlantic Region', 'New England', 'Ultrasonography'] | 20,940,248 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['A07.015.114.186'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.5... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Manic episodes are associated with grey matter volume reduction - a voxel-based morphometry brain analysis. | OBJECTIVE: To investigate whether the lifetime number of affective episodes or illness duration is associated with changes in local grey matter volume, in patients with bipolar I disorder without comorbid conditions.METHOD: Magnetic resonance imaging scans of 55 patients with bipolar I disorder were analysed using VBM.... | ['Adult', 'Bipolar Disorder', 'Brain', 'Brain Mapping', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Male', 'Myelin Sheath', 'Prefrontal Cortex', 'Time Factors'] | 20,712,826 | [['M01.060.116'], ['F03.084.500'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1. | AIM: The mTOR-inhibitor rapamycin has shown antitumor activity in various tumors. Bedside observations have suggested that rapamycin may be effective as a treatment for colorectal carcinomatosis.METHODS: We established an orthotopic syngenic model by transplanting CT26 peritoneal tumors in Balb/C mice and an orthotopic... | ['Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Colorectal Neoplasms', 'Fluorouracil', 'Humans', 'Mice', 'Organoplatinum Compounds', 'Oxaliplatin', 'Peritoneal Neoplasms', 'Sirolimus', 'Tissue Inhibitor of Metalloproteinase-1', 'Treatment Outcome', 'Xenograft Model Antitumor Assays'] | 19,565,301 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetic landscape of open chromatin in yeast. | Chromatin regulation underlies a variety of DNA metabolism processes, including transcription, recombination, repair, and replication. To perform a quantitative genetic analysis of chromatin accessibility, we obtained open chromatin profiles across 96 genetically different yeast strains by FAIRE (formaldehyde-assisted ... | ['Base Sequence', 'Binding Sites', 'Chromatin', 'Chromosome Mapping', 'Gene Expression Regulation, Fungal', 'Oligonucleotide Array Sequence Analysis', 'Phenotype', 'Quantitative Trait Loci', 'Regulatory Sequences, Nucleic Acid', 'Saccharomyces cerevisiae', 'Telomere', 'Transcription Factors'] | 23,408,895 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['E05.393.183'], ['G05.308.330'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['G05.695'], ['G05.360.340.024.380.937'], ['G02.111.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function. | Live probiotic bacteria are effective in reducing gut permeability and inflammation. We have previously shown that probiotics release peptide bioactive factors that modulate epithelial resistance in vitro. The objectives of this study were to determine the impact of factors released from Bifidobacteria infantis on inte... | ['Animals', 'Bifidobacterium', 'Cell Line, Tumor', 'Culture Media, Conditioned', 'Gene Deletion', 'Gene Expression Regulation', 'Humans', 'Interleukin-10', 'Intestines', 'Membrane Proteins', 'Mice', 'Mitogen-Activated Protein Kinase Kinases', 'Phosphorylation', 'Probiotics'] | 18,787,064 | [['B01.050'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['A11.251.210.190', 'A11.251.860.180'], ['D27.720.470.305.250', 'E07.206.250'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Enhancing palliative care for low-income elders with chronic disease: feasibility of a hospice consultation model. | Challenges exist in assimilating palliative care within community-based services for nursing home eligible low-income elders with complex chronic illness as they approach the end of life (EOL). This study assessed the feasibility of a consultation model, with hospice clinicians working with three Care Wisconsin Partner... | ['Attitude to Death', 'Chronic Disease', 'Cooperative Behavior', 'Focus Groups', 'Hospice Care', 'Humans', 'Independent Living', 'Long-Term Care', 'Longitudinal Studies', 'Palliative Care', 'Patient Care Team', 'Poverty', 'Social Work', 'Systems Integration'] | 25,494,931 | [['F01.100.125', 'N05.300.125'], ['C23.550.291.500'], ['F01.145.813.115'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E02.760.905.400', 'N02.421.585.905.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.050.500', 'N01.224.791.550', 'N06.850.505.400.800.550'], ['E02.760.476', 'N02.4... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Illness perceptions, beliefs in medicine and medication non-adherence among South Dakota minority women with diabetes: a pilot study. | BACKGROUND: The objectives of this study are to describe the illness perceptions and medication beliefs of minority women with diabetes and to examine if these beliefs have an impact on medication non-adherence.METHODS: Minority women who had been diagnosed with diabetes within the past six months, taking prescribed me... | ['Adaptation, Psychological', 'Adult', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Indians, North American', 'Middle Aged', 'Minority Groups', 'Patient Compliance', 'Pilot Projects', 'South Dakota'] | 22,016,925 | [['F01.058'], ['M01.060.116'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['M01.060.116.630'], ['I01.880.853.300'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.33... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Transoral versus extraoral reduction of mandible fractures: a comparison of complication rates and other factors. | OBJECTIVE: This retrospective study evaluates results and complications of the transoral and extraoral approaches for open reduction and internal fixation of mandibular body, angle, and ramus fractures. Our aim was to describe advantages and disadvantages of the techniques and to develop criteria for choosing between s... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Incidence', 'Jaw Fixation Techniques', 'Male', 'Mandibular Fractures', 'Middle Aged', 'Oral Surgical Procedures', 'Postoperative Complications', 'Retrospective Studies'] | 12,601,317 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E04.545.440', 'E06.645.440'], ['C10.900.300.284.500.400.255', 'C26.404.750... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative genomics on DKK2 and DKK4 orthologs. | WNT family proteins activate the beta-catenin - TCF pathway to induce carcinogenesis through cell fate determination, and also activate the planar cell polarity (PCP) pathway to induce cell motility and metastasis. DKK1, DKK2, DKK3 and DKK4 are secreted-type WNT signaling modulators belonging to the Dickkopf family. He... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Binding Sites', 'Computational Biology', 'Exons', 'Genes', 'Genomics', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Introns', 'Mice', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Proteins', 'Proteomics', 'Rats', 'Sequence Alignment', 'Seque... | 16,077,958 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['H01.158.273.180', 'L01.313.124'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Therapeutic arthroscopy of the knee. | This paper describes transcutaneous therapeutic procedures performed during arthroscopy. Sixty-six patients were treated. Small loose bodies were flushed out through the arthroscope in 7 cases. In 19 of 24 knees a loose body 0.5-2 cm in size was extracted either with a Dormia stone-dislodger or a pituitary rongeur. In ... | ['Adolescent', 'Adult', 'Aged', 'Convalescence', 'Endoscopes', 'Endoscopy', 'Female', 'Humans', 'Knee Joint', 'Male', 'Menisci, Tibial', 'Middle Aged'] | 581,583 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.562'], ['E07.230.220', 'E07.858.240'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['A02.165.308.538.500', 'A02.835.583.475.590', 'A10.165.382.350.163.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Temporal stability of ADHD in the high-IQ population: results from the MGH Longitudinal Family Studies of ADHD. | OBJECTIVE: The diagnosis of attention-deficit/hyperactivity disorder (ADHD) in high-IQ youths remains controversial.METHOD: To further explore the diagnostic validity of ADHD in this population, we studied two cohorts of high-IQ youths, both with and without ADHD, across a 4.5-year period.RESULTS: Compared to those wit... | ['Achievement', 'Adolescent', 'Anxiety', 'Attention Deficit Disorder with Hyperactivity', 'Attention Deficit and Disruptive Behavior Disorders', 'Child', 'Comorbidity', 'Female', 'Humans', 'Intelligence', 'Longitudinal Studies', 'Male', 'Mood Disorders', 'Personality Assessment', 'Psychometrics', 'Reproducibility of Re... | 18,520,956 | [['F01.658.059', 'F02.784.629.054'], ['M01.060.057'], ['F01.470.132'], ['F03.625.094.150'], ['F03.625.094'], ['M01.060.406'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oculomotor capture in ADHD. | It is generally thought that deficits in response inhibition form an important area of dysfunction in patients with attention-deficit/hyperactivity disorder (ADHD). However, recent research using visual search paradigms seems to suggest that these inhibitory deficits do not extend towards inhibiting irrelevant distract... | ['Adolescent', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Diagnostic and Statistical Manual of Mental Disorders', 'Humans', 'Inhibition, Psychological', 'Male', 'Memory, Short-Term', 'Reaction Time', 'Saccades', 'Visual Perception'] | 18,416,506 | [['M01.060.057'], ['F03.625.094.150'], ['M01.060.406'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F02.463.425.540.407'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['G14.350.500'], ['F02.463.593.932']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Glandular inclusions in inguinal hernial sacs and spermatic cords. M?llerian-like remnants confused with functional reproductive structures. | Small, glandular inclusions are present in approximately 6% of hernial sacs from prepubertal males. Identical structures may be present in the spermatic cord. Histologically, these are composed of ciliated, low columnar epithelium with eosinophilic cytoplasm and basal nuclei. A mantle of fibrous tissue surrounds each g... | ['Adolescent', 'Child', 'Child, Preschool', 'Epithelium', 'Genitalia, Male', 'Hernia, Inguinal', 'Humans', 'Infant', 'Male', 'Mullerian Ducts', 'Spermatic Cord'] | 6,741,877 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['A10.272'], ['A05.360.444'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A16.623'], ['A05.360.444.777']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Leonard A. Jason: Award for Distinguished Professional Contributions to Applied Research. | The Award for Distinguished Professional Contributions to Applied Research is given to a psychologist whose research has led to important discoveries or developments in the field of applied psychology. To be eligible, this research should have led to innovative applications in an area of psychological practice, includi... | ['Awards and Prizes', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Psychology, Applied', 'Research'] | 26,618,967 | [['K01.150'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784'], ['H01.770.644']] | ['Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Separating color from color contrast. | Visual objects can be described by their color and by their color contrast. For example, a red disk in front of a white background appears "red with high color contrast," whereas a red disk in front of a slightly less-saturated red background will appear "red with low color contrast." This paper examines the visual res... | ['Adaptation, Ocular', 'Adolescent', 'Adult', 'Color Perception', 'Contrast Sensitivity', 'Humans', 'Photic Stimulation', 'Space Perception'] | 18,318,611 | [['G14.020'], ['M01.060.057'], ['M01.060.116'], ['F02.463.593.932.217'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.723.729'], ['F02.463.593.778']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression of the long noncoding RNA RP11-169D4.1-001 in Hypopharyngeal Squamous cell carcinoma tissue and its clinical significance. | BACKGROUND: Increased research efforts have demonstrated that lncRNAs are associated with multiple head and neck tumors and play important roles in cancer. We previously found that RP11-169D4.1-001 plays a tumor-suppressive role in laryngeal cancer, but its function in human hypopharyngeal squamous cell carcinoma (HSCC... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Hypopharyngeal Neoplasms', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'RNA, Long Noncoding', 'ROC Curve'] | 31,512,299 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.485'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of anethole dithiolthione on human platelet aggregation. | Anethole dithiolthione (ADT) (10 mumol/l) inhibited platelet aggregation and the formation of thromboxane (Tx)B2 in plasma in response to adenosine diphosphate (ADP), epinephrine and arachidonic acid (AA). ADT partially inhibited platelet aggregation and TxB2 formation in plasma induced by thrombin, phorbol myristate a... | ['Adenosine Diphosphate', 'Adult', 'Anethole Trithione', 'Arachidonic Acid', 'Aspirin', 'Butylated Hydroxytoluene', 'Humans', 'In Vitro Techniques', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Radioimmunoassay', 'Thrombin', 'Thromboxane B2'] | 1,497,692 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.116'], ['D02.355.601.200.100', 'D02.355.726.158.100', 'D02.455.426.559.389.657.654.158.100', 'D02.886.753.077'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D02.455.426.559.389.657.410.595.176'], ['D02.455.426.559.38... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of 5-fluorouracil on gastrointestinal carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats. | This study was undertaken to determine the effect of 5-fluorouracil on gastrointestinal carcinogenesis. Sixty rats were divided into three groups of 20 rats each. All rats were exposed to N-methyl-N'-nitro-N-nitrosoguanidine for the first 20 weeks. Group 1 rats received intraperitoneal injections of 5-fluorouracil for ... | ['Adenocarcinoma', 'Animals', 'Antimetabolites, Antineoplastic', 'Carcinogens', 'Carcinoma, Squamous Cell', 'Fluorouracil', 'Gastrointestinal Neoplasms', 'Injections, Intraperitoneal', 'Male', 'Methylnitronitrosoguanidine', 'Rats', 'Rats, Wistar'] | 9,952,226 | [['C04.557.470.200.025'], ['B01.050'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D27.888.569.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D03.383.742.698.875.404'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['E02.319.267.530.490'], ['D02.078.370.649.400', 'D02.654.567... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bladder Outlet Obstruction Induced by the Compression of Displaced Hemipelvic Prosthesis After Pelvic Reconstruction: A Case Report. | Bladder outlet obstruction (BOO) is a common urological condition usually caused by benign prostatic hyperplasia, prostate cancer, urethral stricture, rarely by compression of surrounding organs. Herein we presented a BOO patient caused by the compression of displaced hemipelvic prosthesis after pelvic reconstruction. ... | ['Foreign Bodies', 'Humans', 'Male', 'Middle Aged', 'Pelvic Bones', 'Pelvis', 'Postoperative Complications', 'Prostheses and Implants', 'Prosthesis Failure', 'Prosthesis Implantation', 'Urinary Bladder Neck Obstruction'] | 31,352,018 | [['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.835.232.043.825'], ['A01.923.600'], ['C23.550.767'], ['E07.695'], ['C23.550.767.865', 'E05.325.771'], ['E04.650'], ['C12.777.767.700.962', 'C12.777.829.760', 'C13.351.968.767.700.850', 'C13.351.968.829.601']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of adenosine receptor subtypes expressed in the human endothelial-like ECV304 cells. | Adenosine, acting through its receptors, is a potent endogenous regulator of endothelial cells. The cultured endothelial cells expressing adenosine receptors are thus important for elucidation of molecular mechanism of adenosine functions in these cell systems. Therefore, identification of adenosine receptors in the hu... | ['Cell Line', 'Cyclic AMP', 'Endothelial Cells', 'Humans', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'RNA, Messenger', 'Radioligand Assay', 'Receptors, Purinergic P1', 'Reverse Transcriptase Polymerase Chain Reaction'] | 15,795,521 | [['A11.251.210'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.567.249.500', 'D12.644.360.450.169.500', 'D12.776.476.450.169.500'], ['D08.811.913.696.620.682.700.567.249.7... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of agriculture-based phytoremediation in Pacific island ecosystems using trisector planters. | It is difficult to directly evaluate the efficacy of phytoremediation of petroleum hydrocarbon contaminants embedded in deep soil layers, especially if the contaminants are of relatively low concentration and are unevenly distributed. This report describes the greenhouse and laboratory experiments carried out to evalua... | ['Agriculture', 'Ecosystem', 'Humans', 'Plant Roots', 'Soil', 'Trees'] | 15,224,773 | [['J01.040'], ['G16.500.275.157', 'N06.230.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A18.400'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.915']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Glucose utilization by the retinal pigment epithelium: evidence for rapid uptake and storage in glycogen, followed by glycogen utilization. | Glucose utilization and glycogen metabolism by human retinal pigment epithelium (RPE) cultures with high transepithelial resistance maintained on porous Millicell polycarbonate filters, were quantified by fluorophore-assisted carbohydrate electrophoresis (FACE). Glucose uptake was more efficient at the apical surface o... | ['Aminoacridines', 'Cells, Cultured', 'Culture Media', 'Electrophoresis', 'Fluorescent Dyes', 'Glucan 1,4-alpha-Glucosidase', 'Glucose', 'Glucose Transport Proteins, Facilitative', 'Glucose Transporter Type 1', 'Glycogen', 'Humans', 'Immunohistochemistry', 'Pigment Epithelium of Eye', 'Polysaccharides', 'Reverse Transc... | 16,690,055 | [['D03.633.300.046.250'], ['A11.251'], ['D27.720.470.305', 'E07.206'], ['E05.196.401', 'E05.301.300'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D08.811.277.450.420.375'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500', 'D12.776.157.530.937.563', 'D12.776.543.585.500.500', 'D12.776.543.585.937.625'], ['D12... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential expression of endothelial nutrient transporters (MCT1 and GLUT1) in the developing eyes of mice. | The blood-brain barrier in the neonatal brain expresses the monocarboxylate transporter (MCT)-1 rather than the glucose transporter (GLUT)-1, due to the special energy supply during the suckling period. The hyaloid vascular system, consisting of the vasa hyaloidea propria and tunica vasculosa lentis, is a temporary vas... | ['Animals', 'Animals, Newborn', 'Biological Transport', 'Eye', 'Female', 'Glucose Transporter Type 1', 'Immunohistochemistry', 'Mice', 'Microscopy, Electron', 'Models, Animal', 'Monocarboxylic Acid Transporters', 'Pigment Epithelium of Eye', 'Pregnancy', 'Pregnancy, Animal', 'Symporters'] | 27,793,618 | [['B01.050'], ['B01.050.050.282'], ['G03.143'], ['A01.456.505.420', 'A09.371'], ['D12.776.157.530.500.500.500', 'D12.776.157.530.937.563.500', 'D12.776.543.585.500.500.500', 'D12.776.543.585.937.625.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Fat tissue histological study at indocyanine green-mediated photothermal/photodynamic treatment of the skin in vivo. | Histological slices of skin samples with the subcutaneous adipose tissue after photothermal/photodynamic treatment are analyzed. In the case of subcutaneous indocyanine green injection and 808-nm diode laser exposure of the rat skin site in vivo, the greatest changes in tissue condition were observed. Processes were ch... | ['Adipose Tissue', 'Animals', 'Cell Survival', 'Female', 'Hyperthermia, Induced', 'Indocyanine Green', 'Lasers', 'Lipolysis', 'Photochemotherapy', 'Rats', 'Skin'] | 22,612,149 | [['A10.165.114'], ['B01.050'], ['G04.346'], ['E02.565'], ['D03.633.100.473.400'], ['E07.632.490', 'E07.710.520'], ['G02.111.534', 'G03.458.500'], ['E02.186.500', 'E02.319.685', 'E02.774.722'], ['B01.050.150.900.649.313.992.635.505.700'], ['A17.815']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A biostatistical insight into the As(2)O(3) high dilution effects on the rate and variability of wheat seedling growth. | BACKGROUND: Most criticism of homeopathy concerns the lack of scientific bases and theoretical models. Fundamental research could make important contributions to our understanding of the mechanisms of action of homeopathic treatments. Plant-based bioassays are suitable for basic research -- lacking the placebo effect a... | ['Arsenic Trioxide', 'Arsenicals', 'Germination', 'Growth Inhibitors', 'Homeopathy', 'Humans', 'Models, Biological', 'Oxides', 'Phytotherapy', 'Reproducibility of Results', 'Statistics as Topic', 'Triticum'] | 16,230,857 | [['D01.075.038', 'D01.650.550.125'], ['D01.075', 'D02.129'], ['G07.345.625.249', 'G15.357'], ['D27.505.696.377.450'], ['E02.190.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['D01.248.497.158.685', 'D01.650.550'], ['E02.190.755'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Serological characterisation of Ureaplasma urealyticum strains by enzyme-linked immunosorbent assay (ELISA). | A modification of enzyme-linked immunosorbent assay (ELISA) was developed for the serological characterisation and identification of strains of Ureaplasma urealyticum. The eight recognised human serotypes of U urealyticum and antisera produced against them were used as reference for the evaluation and standardisation o... | ['Antigens, Bacterial', 'Dose-Response Relationship, Immunologic', 'Enzyme-Linked Immunosorbent Assay', 'Immune Sera', 'Serotyping', 'Ureaplasma'] | 7,076,871 | [['D23.050.161'], ['G12.300'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['E01.370.225.812.742', 'E01.370.225.87... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
How nonmagnetic particles intensify rotational diffusion in magnetorheological fluids. | In this work we propose a mechanism to explain the enhancement of the magnetic-field-induced yield stress when nonmagnetic particles are added to magnetic particulate suspensions, i.e., two-component suspensions. Our main hypothesis is that the nonmagnetic particles collide with the field-induced magnetic aggregates un... | ['Diffusion', 'Hydrodynamics', 'Magnetic Phenomena', 'Particle Size', 'Polymethyl Methacrylate', 'Rheology', 'Rotation', 'Stochastic Processes'] | 25,122,306 | [['G01.202', 'G02.196'], ['G01.342'], ['G01.358'], ['G02.712'], ['D02.241.081.069.800.550.500', 'D05.750.716.822.111.650.605.500', 'D25.720.716.822.111.650.605.500', 'J01.637.051.720.716.822.111.650.605.500'], ['E05.830', 'H01.671.808'], ['G01.482.703'], ['E05.318.740.996', 'G17.830', 'N05.715.360.750.770', 'N06.850.52... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
A "Handy" tool for hypertension prediction: Dermatoglyphics. | BACKGROUND: Fingerprints studied by dermatoglyphics are unique for a given individual. It depends on the genetic makeup of an individual. Hypertension, a harbinger of many complications, is determined by genetic and environmental factors. In this observational study, we tried to find an association of palmar dermatogly... | ['Adult', 'Cross-Sectional Studies', 'Dermatoglyphics', 'Female', 'Fingers', 'Genetic Predisposition to Disease', 'Humans', 'Hypertension', 'Incidence', 'India', 'Male', 'Middle Aged', 'Retrospective Studies'] | 30,595,242 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.740.225.500.375', 'I01.198.780.937.343', 'N04.452.910.099.500'], ['A01.378.800.667.430'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.308.985... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
5-Androstene-3â,17â-diol promotes recovery of immature hematopoietic cells following myelosuppressive radiation and synergizes with thrombopoietin. | PURPOSE: 5-Androstene-3â,17â-diol (5-AED) stimulates recovery of hematopoiesis after exposure to radiation. To elucidate its cellular targets, the effects of 5-AED alone and in combination with (pegylated) granulocyte colony-stimulating factor and thrombopoietin (TPO) on immature hematopoietic progenitor cells were eva... | ['Androstenediol', 'Animals', 'Blood Cells', 'Bone Marrow', 'Bone Marrow Cells', 'Colony-Forming Units Assay', 'Dose Fractionation, Radiation', 'Drug Synergism', 'Drug Therapy, Combination', 'Granulocyte Colony-Stimulating Factor', 'Hematopoietic Stem Cells', 'Mice', 'Mice, Inbred BALB C', 'Thrombopoietin', 'Whole-Body... | 22,672,754 | [['D04.210.500.054.079.429.154.050', 'D06.472.334.851.968.750'], ['B01.050'], ['A11.118', 'A15.145.229'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['E02.815.639.200'], ['G07.690.773.968.477'], ['E02.319.310'], ['D12.644.276.374.410.240.350', 'D12.776.395.24... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetics of alfentanil and clinical responses during cardiac surgery. | This study assessed the pharmacokinetic and pharmacodynamic behaviour of alfentanil during and after coronary artery bypass grafting (CABG). Twenty-eight patients with good ventricular function having CABG were divided into three groups and premedicated with morphine 0.1 mg.kg-1 IM, scopolamine 0.005 mg.kg-1 IM and dia... | ['Alfentanil', 'Anesthesia, Intravenous', 'Coronary Artery Bypass', 'Female', 'Hemodynamics', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged'] | 2,295,106 | [['D03.383.621.265.100'], ['E03.155.308'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['M01.060.116.630']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Harm reduction therapy with families and friends of people with drug problems. | This article describes and illustrates the ongoing development of a treatment for working with families and friends of drug users using harm reduction principles. The author was instrumental in applying harm reduction principles to substance abuse and has used these same principles to help families deal with the pessim... | ['Adult', 'Anecdotes as Topic', 'Family Therapy', 'Female', 'Friends', 'Harm Reduction', 'Humans', 'Self-Help Groups', 'Substance-Related Disorders'] | 20,049,921 | [['M01.060.116'], ['K01.517.067'], ['F04.754.864.581.273'], ['M01.252'], ['F01.145.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.782'], ['C25.775', 'F03.900']] | ['Named Groups [M]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Wanting a child]. | To want a child and to want to have a child are notions receiving renewed interest ever since the generalization of contraception and even more recently, the new methods of procreation. These two notions are compared and tested against biological data across historical, psychoanalytic and sociological works. A brief re... | ['Female', 'Humans', 'Male', 'Maternal Behavior', 'Motivation', 'Parents', 'Pregnancy'] | 3,659,206 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.215'], ['F01.658', 'F01.752.543.500.750'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['G08.686.784.769']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Adverse reactions to carcinostatics and countermeasures]. | As adverse reactions to the combination treatment by the digestive system, we observed the occurrence of nausea and vomiting in 15% of the cases who received FTP treatment consisting of 5-FU, toyomicin and prednisone, 25% of the cases who received MFU treatment consisting of MMC, 5-FU and ACNU, and in 64% of the cases ... | ['Antiemetics', 'Antineoplastic Combined Chemotherapy Protocols', 'Carbazilquinone', 'Chemical and Drug Induced Liver Injury', 'Chromomycin A3', 'Fluorouracil', 'Humans', 'Liver', 'Mitomycin', 'Mitomycins', 'Nausea', 'Nimustine', 'Organoplatinum Compounds', 'Prednisone', 'Vomiting'] | 2,499,262 | [['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.806.250.180', 'D03.383.097.217.300'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['D09.408.210.209'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Foley catheter practices and knowledge among Minnesota physicians. | BACKGROUND: Urinary catheter use is common, and physicians are often unaware of the presence of a catheter in a patient. Despite this, and despite a recent policy change classifying catheter-associated urinary tract infection (CAUTI) as nonreimbursable, little is known regarding physicians' knowledge and attitudes rega... | ['Attitude of Health Personnel', 'Catheter-Related Infections', 'Data Collection', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Internet', 'Minnesota', 'Physicians', 'Surveys and Questionnaires', 'Urinary Catheterization', 'Urinary Tract Infections'] | 20,605,268 | [['F01.100.050', 'N05.300.100'], ['C01.195'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['M01.526.485.810', 'N02.360.810']... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Analysis of genes, pathways and networks involved in disease severity and age at onset in primary-progressive multiple sclerosis. | BACKGROUND: The role of genetic factors in influencing the clinical expression of multiple sclerosis (MS) is unclear.OBJECTIVE: The objective of this paper is to identify genes, pathways and networks implicated in age at onset (AAO) and severity, measured using the Multiple Sclerosis Severity Score (MSSS), of primary-p... | ['Adult', 'Age of Onset', 'Female', 'Gene Regulatory Networks', 'Genome-Wide Association Study', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Multiple Sclerosis, Chronic Progressive', 'Severity of Illness Index'] | 25,583,839 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['G05.360.080.689.360'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.63... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reactivity of primate sera to foamy virus Gag and Bet proteins. | In order to establish criteria for the serodiagnosis of foamy virus infections we investigated the extent to which sera from infected individuals of human and primate origin react with structural and non-structural virus proteins in immunoblot assays. Using lysates from infected cells as the source of virus antigen, an... | ['Animals', 'Cell Line', 'Chlorocebus aethiops', 'Cricetinae', 'Cross Reactions', 'Gene Products, gag', 'Genes, gag', 'Gorilla gorilla', 'Humans', 'Insecta', 'Kidney', 'Lung', 'Macaca mulatta', 'Molecular Sequence Data', 'Molecular Weight', 'Pan troglodytes', 'Phosphorylation', 'Pongo pygmaeus', 'Primates', 'Recombinan... | 7,931,149 | [['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['B01.050.150.900.649.313.992.635.075.250'], ['G12.122.281'], ['D12.776.775.330', 'D12.776.964.775.350', 'D12.776.964.970.600.850.350'], ['G05.360.340.024.340.364.875.258', 'G05.360.340.358.024.875.258', 'G05.360.340.358.840.500.258... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Critical analysis of rhinovirus RNA load quantification by real-time reverse transcription-PCR. | Rhinoviruses are the most frequent cause of human respiratory infections, and quantitative rhinovirus diagnostic tools are needed for clinical investigations. Although results obtained by real-time reverse-transcription PCR (RT-PCR) assays are frequently converted to viral RNA loads, this presents several limitations r... | ["5' Untranslated Regions", 'Genetic Variation', 'Humans', 'Picornaviridae Infections', 'RNA, Viral', 'Real-Time Polymerase Chain Reaction', 'Reproducibility of Results', 'Reverse Transcriptase Polymerase Chain Reaction', 'Rhinovirus', 'Viral Load'] | 22,718,934 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.782.687'], ['D13.444.735.828'], ['E05.393.620.500.706'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The development of the hypothalamic-pituitary-gonadal axis in juvenile great tits. | The development of the hypolamic-pituitary-gonadal axis in free-living nestling great tits (Parus major) was studied from the day of hatching until about 40 days of age. The hypothalamic content of GnRH was low during the entire nestling period, although a significant increase was noted between 6 and 9 days of age. The... | ['Aging', 'Animals', 'Birds', 'Estradiol', 'Female', 'Gonadotropin-Releasing Hormone', 'Hypothalamus', 'Luteinizing Hormone', 'Male', 'Orchiectomy', 'Ovary', 'Pituitary Gland', 'Sex Characteristics', 'Testis', 'Testosterone'] | 8,812,358 | [['G07.345.124'], ['B01.050'], ['B01.050.150.900.248'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D06.472.699.322.576.4... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds). | BACKGROUND: Altered neuronal vulnerability underlies many diseases of the human nervous system, resulting in degeneration and loss of neurons. The neuroprotective slow Wallerian degeneration (Wlds) mutation delays degeneration in axonal and synaptic compartments of neurons following a wide range of traumatic and diseas... | ['Animals', 'Axons', 'Cell Cycle', 'Cell Line', 'Cerebellum', 'Chromosome Pairing', 'Humans', 'Mice', 'Neurons', 'Wallerian Degeneration'] | 18,570,652 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G04.144'], ['A11.251.210'], ['A08.186.211.132.810.428.200'], ['G04.144.220.220.687.883.250', 'G04.144.220.220.781.906.250', 'G05.113.220.687.883.250', 'G05.113.220.781.906.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy and safety of secondary prophylactic vs. on-demand sucrose-formulated recombinant factor VIII treatment in adults with severe hemophilia A: results from a 13-month crossover study. | BACKGROUND: Hemarthroses in severe hemophilia precipitate physical, psychosocial and financial difficulties.OBJECTIVE: To compare the effects of secondary prophylaxis with on-demand sucrose-formulated recombinant factor VIII (rFVIII-FS) therapy in severe hemophilia A.PATIENTS AND METHODS: This open-label study included... | ['Adult', 'Chemistry, Pharmaceutical', 'Coagulants', 'Cross-Over Studies', 'Drug Administration Schedule', 'Europe', 'Factor VIII', 'Hemarthrosis', 'Hemophilia A', 'Home Infusion Therapy', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Prospective Studies', 'Secondary Prevention', 'Severity of Illness Inde... | 19,817,995 | [['M01.060.116'], ['H01.158.703.007', 'H01.181.466'], ['D27.505.954.502.270'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E02.319.283'], ['Z01.542'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['C05.550.459', 'C23.550.414.794'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
A simple computer program for optimization of source loading in cervical intracavitary applicators. | A computer program has been developed to aid in the brachytherapy of cancer of the cervix. Using a least-squares minimization algorithm, the program will optimize the source loading in intracavitary applicators so as to reproduce, as nearly as physical considerations allow, the dose distribution requested by the user. ... | ['Computers', 'Female', 'Humans', 'Methods', 'Radiotherapy Dosage', 'Uterine Cervical Neoplasms'] | 831,930 | [['L01.224.230.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['E02.815.639'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.762.850', 'C13.351.937.418.875.850']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-term, high-dose disulfiram in the treatment of alcohol abuse. | A patient who had experienced most of the standard methods of managing alcohol abuse found that during 11 years of treatment, the most consistently effective intervention has been the taking of disulfiram under family supervision. He has received 600 mg daily almost continuously for over six years without side-effects.... | ['Adult', 'Alcoholism', 'Combined Modality Therapy', 'Disulfiram', 'Humans', 'Male', 'Psychotherapy, Group'] | 8,298,843 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E02.186'], ['D02.241.081.251.869.220.250', 'D02.886.520.150.175', 'D02.886.706.200.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.754.864.581']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter. | The homeobox genes Xlim-1 and goosecoid (gsc) are coexpressed in the Spemann organizer and later in the prechordal plate that acts as head organizer. Based on our previous finding that gsc is a possible target gene for Xlim-1, we studied the regulation of gsc transcription by Xlim-1 and other regulatory genes expressed... | ['Animals', 'Base Sequence', 'DNA', 'DNA Primers', 'DNA-Binding Proteins', 'Gene Expression Regulation, Developmental', 'Goosecoid Protein', 'Homeodomain Proteins', 'LIM-Homeodomain Proteins', 'Molecular Sequence Data', 'Protein Binding', 'Repressor Proteins', 'Sequence Homology, Nucleic Acid', 'Transcription Factors',... | 10,926,781 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D12.776.260'], ['G05.308.310'], ['D12.776.260.400.186', 'D12.776.930.315'], ['D12.776.260.400'], ['D12.776.260.529', 'D12.776.512.249'], ['L01.453.245.667'], ['G02.111.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Investigating the role of anodic potential in the biodegradation of carbamazepine in bioelectrochemical systems. | Anode potential is a critical factor in the biodegradation of organics in bioelectrochemical systems (BESs), but research on these systems with complex recalcitrant co-substrates at set anode potentials is scarce. In this study, carbamazepine (CBZ) biodegradation in a BES was examined over a wide range of set anode pot... | ['Bacteria', 'Biodegradation, Environmental', 'Bioelectric Energy Sources', 'Carbamazepine', 'Electrodes'] | 31,229,828 | [['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.305.124.150'], ['D03.633.300.240.127'], ['E07.305.250']] | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death. | Mitochondrial trifunctional protein (MTP) is a hetero-octamer of four alpha and four beta subunits that catalyzes the final three steps of mitochondrial long chain fatty acid beta-oxidation. Human MTP deficiency causes Reye-like syndrome, cardiomyopathy, or sudden unexpected death. We used gene targeting to generate an... | ['Animals', 'Animals, Newborn', 'Blood Chemical Analysis', 'Crosses, Genetic', 'Death, Sudden', 'Diaphragm', 'Disease Models, Animal', 'Embryonic and Fetal Development', 'Female', 'Fetal Growth Retardation', 'Gene Targeting', 'Humans', 'Hypoglycemia', 'Immunoblotting', 'Liver', 'Male', 'Mice', 'Mice, Knockout', 'Mitoch... | 11,390,422 | [['B01.050'], ['B01.050.050.282'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E05.393.281'], ['C23.550.260.322'], ['A02.633.567.900.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.345.500.325', 'G08.686.784.170'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['E05.393.335'], ['B01.050.150.900.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quality circles in ambulatory care: state of development and future perspective in Germany. | OBJECTIVE: To survey the quantitative development of quality circles (peer review groups; QC) and their moderators in ambulatory care in Germany, to describe approaches to documentation and evaluation, to establish what types of facilities and support is available and to assess opinions on the future importance of QC.D... | ['Ambulatory Care', 'Cross-Sectional Studies', 'Forecasting', 'Germany', 'Humans', 'Management Quality Circles', 'Peer Review, Health Care', 'Surveys and Questionnaires', 'Total Quality Management'] | 10,030,785 | [['E02.760.106', 'N02.421.585.106'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.320'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.677.420'], ['F01.829.316.549.690', 'I01.880.604.640.690', 'N03.706.700.690', 'N04.761.616', 'N05.715.680'], ['E05.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Reducing the rate of fistula: does a fibrin sealant act as an adjunct in pharyngeal closure? A two-centre experience. | BACKGROUND: Pharyngocutaneous fistula is a troublesome complication. Recently, synthetic materials such as fibrin sealant have been used as a secondary measure to treat fistula. This work assessed whether the primary use of fibrin sealant can reduce the rate of fistula.METHOD: A retrospective review of 50 cases from 2 ... | ['Cutaneous Fistula', 'Fibrin Tissue Adhesive', 'Humans', 'Laryngectomy', 'Pharyngeal Diseases', 'Retrospective Studies', 'Salvage Therapy', 'Treatment Outcome'] | 32,741,379 | [['C17.800.135', 'C23.300.575.150'], ['D12.776.124.270.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.580.369'], ['C07.550', 'C09.775'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of Structured Teaching Programme on Knowledge, Anxiety and Behavioural Response of Patients Undergoing Endoscopy at a Tertiary Care Hospital. | Upper gastrointestinal endoscopy is a common OPD procedure carried out for diagnostic as well as therapeutic purpose. Limited time for interaction between patients and health workers leads to increased anxiety among patients. This study was carried among 50 patients undergoing planned, diagnostic upper GI endoscopy for... | ['Adult', 'Aged', 'Anxiety', 'Endoscopy, Gastrointestinal', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'India', 'Male', 'Middle Aged', 'Nursing Process', 'Patient Education as Topic', 'Surveys and Questionnaires', 'Young Adult'] | 30,744,253 | [['M01.060.116'], ['M01.060.116.100'], ['F01.470.132'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['N04.590.233.508'], ['I02.233.332.500'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Decision-making in gender reassignment surgery]. | The prescribing of hormones and the performing of gender reassignment surgery on a healthy body are dangerous and irreversible acts. To ensure patients' safety, endocrinologists and surgeons must use the skills of experienced psychiatrists to create a differential diagnosis, evaluate any frailties and weigh up the risk... | ['Decision Making', 'Humans', 'Sex Reassignment Surgery'] | 30,879,628 | [['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.906.500', 'E04.680.750', 'E04.950.449']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Doxorubicin induced apoptosis was potentiated by neferine in human lung adenocarcima, A549 cells. | Doxorubicin (DOX) is the best anticancer agent that has ever been used, but acquired tumor resistance and dose limiting toxicity are major road blocks. Concomitant use of natural compounds is a promising strategy to overcome this problem. Neferine, a proven anticancer agent is found in green embryos of lotus seed. The ... | ['Antibiotics, Antineoplastic', 'Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis', 'Benzylisoquinolines', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Doxorubicin', 'Glutathione', 'Humans', 'L-Lactate Dehydrogenase', 'Membrane Potential, Mitochondrial', 'Myocytes, Cardiac', 'NF-kappa B', 'Nit... | 24,632,453 | [['D27.505.954.248.106'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G04.146.954.035'], ['D03.132.098', 'D03.633.100.531.085'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of cafeteria diet induced obesity on rat blood amino acid compartmentation. | In female virgin Wistar rats, the effects of a cafeteria-diet induced obesity on blood amino acid levels and their distribution between plasma and blood cells have been studied in fed and 24-hour starved states. Cafeteria diet induced obesity provoked a decrease in total blood cell amino acid content, both in fed and s... | ['Amino Acids', 'Animals', 'Blood Cells', 'Diet', 'Female', 'Obesity', 'Plasma', 'Rats', 'Rats, Inbred Strains', 'Starvation'] | 1,707,611 | [['D12.125'], ['B01.050'], ['A11.118', 'A15.145.229'], ['G07.203.650.240'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Satellite cells are increasingly refractory to activation by nitric oxide and stretch in aged mouse-muscle cultures. | Age-related muscle atrophy or sarcopenia results in progressive loss of muscle function and satellite cells in aging muscle are increasingly refractory to activation that could mitigate atrophy. We know that nitric oxide release triggered by mechanical stretch of skeletal muscle, initiates satellite cell activation in ... | ['Aging', 'Animals', 'Cells, Cultured', 'Female', 'Mice', 'Mice, Inbred C57BL', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Satellite Cells, Skeletal Muscle', 'Stress, Mechanical'] | 19,819,345 | [['G07.345.124'], ['B01.050'], ['A11.251'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['A11.872.620.500.700... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The anterior saphenous veins of the thigh]. | The authors base their argument on a homogeneous series of 75 patients who, in the course of crossectomies and the stripping of the long saphenousvein carried out by the authors, were given a puncture-phlebectomy of the accessory anterior saphenous vein or veins. Firstly they analyse the clinical characteristics of the... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Saphenous Vein', 'Thigh', 'Varicose Veins'] | 4,023,081 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.015.908.819'], ['A01.378.610.750'], ['C14.907.927']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tetrapyrrole biosynthesis in Rhodobacter capsulatus is transcriptionally regulated by the heme-binding regulatory protein, HbrL. | We demonstrate that the expression of hem genes in Rhodobacter capsulatus is transcriptionally repressed in response to the exogenous addition of heme. A high-copy suppressor screen for regulators of hem gene expression resulted in the identification of an LysR-type transcriptional regulator, called HbrL, that regulate... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Consensus Sequence', 'Gene Expression Regulation, Bacterial', 'Heme', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Rhodobacter capsulatus', 'Tetrapyrroles', 'Transcription, Genetic'] | 16,452,440 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.580.175'], ['G05.308.300'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['L01.453.245.667'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo investigations of vascular density and local mitochondrial metabolism after irradiation. | It is obvious that irradiation increases local oxygen uptake. Because the oxygen supply is not altered, a decrease in local oxygen partial pressure may develop. This state may be called relative hypoxia. If the metabolism is altered for a period of at least 24 hrs an increase in angiogenic mitogens, inducing angiogenes... | ['Animals', 'Chick Embryo', 'Colorimetry', 'Kinetics', 'Mitochondria', 'Neovascularization, Physiologic', 'Time Factors', 'Yolk Sac'] | 9,500,036 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['E05.196.922.250'], ['G01.374.661', 'G02.111.490'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G09.330.630'], ['G01.910.857'], ['A10.615.284.981', 'A16.254.750.981', 'A16.331.800']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extreme response style bias in burn survivors. | This paper explores extreme response style to the Life Impact Burn Recovery Evaluation (LIBRE) Profile, a measure of social participation in burn survivors. We fit a Multidimensional Generalized Partial Credit Model (MGPCM) with a positive extreme response style (PERS) factor and compared this model with the original M... | ['Adult', 'Burns', 'Female', 'Humans', 'Male', 'Social Participation', 'Survivors'] | 31,059,527 | [['M01.060.116'], ['C26.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.050.750'], ['M01.860']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Postpartum traditions and nutrition practices among urban Lao women and their infants in Vientiane, Lao PDR. | BACKGROUND/OBJECTIVE: To assess the traditional postpartum practices, mother and child nutritional status and associated factors.SUBJECTS/METHODS: A cross-sectional study in 41 randomly selected villages on the outskirts of Vientiane capital city, Lao PDR (Laos). 300 pairs of infants (< 6 months of age) and their mothe... | ['Adult', 'Body Height', 'Breast Feeding', 'Cross-Sectional Studies', 'Cultural Characteristics', 'Diet', 'Diet Surveys', 'Energy Intake', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant Nutrition Disorders', 'Laos', 'Mothers', 'Postnatal Care', 'Pregnancy', 'Thinness', 'Young Adult'] | 18,000,519 | [['M01.060.116'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.076.201.450.324', 'I01.88... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides. | The synthesis of L-nucleoside analogues containing 2'-vinylic fluoride was accomplished by direct condensation method, and their anti-HIV and anti-HBV activities were evaluated in vitro. The key intermediate 8, the sugar moiety of our target compounds, was prepared from 1,2-O-isopropylidene-L-glyceraldehyde via (R)-2-f... | ['Adenosine', 'Anti-HIV Agents', 'Cell Line', 'Cytosine', 'HIV-1', 'Hepatitis B virus', 'Humans', 'In Vitro Techniques', 'Inhibitory Concentration 50', 'Leukocytes, Mononuclear', 'Purine Nucleosides', 'Pyrimidine Nucleosides', 'Structure-Activity Relationship', 'Virus Replication'] | 10,197,975 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D27.505.954.122.388.077.088'], ['A11.251.210'], ['D03.383.742.698.421'], ['B04.820.650.589.650.350.400'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E05.940.350', 'G07.690.936.563']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recombination between gtfB and gtfC is required for survival of a dTDP-rhamnose synthesis-deficient mutant of Streptococcus mutans in the presence of sucrose. | The rml genes are involved in dTDP-rhamnose synthesis in Streptococcus mutans. A gene fusion between gtfB and gtfC, which both encode extracellular water-insoluble glucan-synthesizing enzymes, accompanied by inactivation of the rml genes was observed for cells grown in the presence of sucrose. The survival rates of rml... | ['Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Glucosyltransferases', 'Recombination, Genetic', 'Rhamnose', 'Streptococcus mutans', 'Sucrose', 'Thymine Nucleotides'] | 10,377,163 | [['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D08.811.913.400.450.460'], ['G05.728'], ['D09.254.799'], ['B03.353.750.737.872.875.520', 'B03.510.400.800.872.875.520', 'B03.510.550.737.872.875.520'], ['D09.698.629.305.770', 'D09.947.750.770'], ['D03.383.742.686... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes of some lipid and lipid peroxidation characteristics in obese people as a result of a low energy diet. | In blood samples of 54 obese persons (13 men, 41 women) some lipid components, malondialdehyde (MDA), and the activities of free radical protecting enzymes superoxide-dismutase (SOD) and glutathione-peroxidase (GSHpx), were determined before and after a seven-day slimming diet of 2.1 MJ/day. Body weight, triglycerides,... | ['Adult', 'Cholesterol', 'Cholesterol, HDL', 'Diet, Reducing', 'Energy Intake', 'Female', 'Glutathione Peroxidase', 'Humans', 'Lipid Peroxidation', 'Lipid Peroxides', 'Lipids', 'Male', 'Malondialdehyde', 'Middle Aged', 'Obesity', 'Superoxide Dismutase', 'Triglycerides'] | 3,239,107 | [['M01.060.116'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['E02.642.249.285', 'G07.203.650.240.285'], ['G07.203.650.240.340'], ['D08.811.682.732.500'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association of shorter mean telomere length with large artery stiffness in patients with coronary heart disease. | BACKGROUND: Accumulating evidence implicates leukocyte telomere length (LTL) shortening as a potential risk predictor for cardiovascular disease. Arterial stiffness chronicles the cumulative burden of cardiovascular disease risk factors. Therefore, the capacity of LTL to predict arterial stiffness was examined.METHODS:... | ['Adult', 'Aged', 'C-Reactive Protein', 'Case-Control Studies', 'Coronary Artery Disease', 'Coronary Vessels', 'Elasticity', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Oxidative Stress', 'Reference Values', 'Reverse Transcriptase Polymerase Chain Reaction', 'Risk Factors', 'Telomere', 'Ultrasonography'] | 21,067,315 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['G01.374.590'], ['B01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of a follow-up program for mild traumatic brain injury in schoolchildren. | INTRODUCTION: Mild traumatic brain injury is a common condition in childhood. Although classified as mild, post-concussive symptoms may persist and interfere with daily activities. Because no established guidelines exist with respect to follow-up medical care for these children, there may be a delay in receiving approp... | ['Adolescent', 'Brain Concussion', 'Child', 'Child, Preschool', 'Cognitive Dysfunction', 'Female', 'Follow-Up Studies', 'Headache', 'Humans', 'Male', 'Problem Behavior', 'Time Factors'] | 27,856,122 | [['M01.060.057'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['M01.060.406'], ['M01.060.406.448'], ['F03.615.250.700'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C2... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Age 40 years and under does not confer superior prognosis in patients with multiple myeloma undergoing upfront autologous stem cell transmplant. | Multiple myeloma (MM) rarely occurs in patients 40 years of age and younger. This young age has been reported to correlate with improved survival in patients with MM. The objective of this study is to describe presenting features and outcomes of patients < or =40 years of age with MM who undergo autologous stem cell tr... | ['Adult', 'Age Factors', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Cohort Studies', 'Combined Modality Therapy', 'Disease-Free Survival', 'Female', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Leukemia, Plasma Cell', 'Male', 'Middle Aged', 'Multiple Myeloma', 'Neoplasms, Second Primary', 'Postopera... | 19,450,753 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.186'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of cytomegalovirus in vitreous, aqueous and conjunctiva by polymerase chain reaction (PCR). | OBJECTIVE: To evaluate the diagnostic value of polymerase chain reaction (PCR) performed on vitreous, aqueous and conjunctiva for the detection of cytomegalovirus in AIDS patients with a clinical diagnosis of cytomegalovirus retinitis.MATERIAL AND METHOD: PCR-based assay was used to detect cytomegalovirus DNA in vitreo... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Aqueous Humor', 'Conjunctiva', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Cytomegalovirus Retinitis', 'Eye Infections, Viral', 'Humans', 'Polymerase Chain Reaction', 'Vitreous Body'] | 15,962,675 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['A09.371.060.067.070', 'A12.207.270.040'], ['A09.371.060.200', 'A09.371.337.168'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], [... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Carbon storage regulator A (CsrA(Bb)) is a repressor of Borrelia burgdorferi flagellin protein FlaB. | The Lyme disease spirochete Borrelia burgdorferi lacks the transcriptional cascade control of flagellar protein synthesis common to other bacteria. Instead, it relies on a post-transcriptional mechanism to control its flagellar synthesis. The underlying mechanism of this control remains elusive. A recent study reported... | ["5' Untranslated Regions", 'Binding Sites', 'Borrelia burgdorferi', 'Cryoelectron Microscopy', 'Electron Microscope Tomography', 'Flagella', 'Flagellin', 'Gene Deletion', 'Gene Expression', 'Gene Expression Regulation, Bacterial', 'Microscopy, Fluorescence', 'Mutation', 'Repressor Proteins'] | 21,999,436 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['G02.111.570.120'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['E01.370.350.825.249', 'E05.595.402.580.239'], ['A11.284.180.29... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anisotropy in an ambiguous kinetic depth effect. | A set of animated stimuli (Lissajous figures), each element of which is physically consistent with two different three-dimensional shapes undergoing rigid rotations about orthogonal axes, is described. Human observers typically show a preference for one shape or the other; this preference may be biased by manipulating ... | ['Anisotropy', 'Depth Perception', 'Humans', 'Kinetics', 'Mathematics', 'Motion Perception', 'Psychophysics'] | 1,569,494 | [['G01.590.040', 'G02.050'], ['F02.463.593.200', 'F02.463.593.778.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['F02.463.593.932.567'], ['E01.370.685', 'F04.096.753']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Discrepancies of current recommendations in breast cancer follow-up: a systematic review. | INTRODUCTION: Management and optimal follow-up of early breast cancer survivors remain up to this day a challenge due to the lack of well-established guidelines. Multiple medical societies, organizations and working groups have provided recommendations for follow-up but there is no uniform, globally approved algorithm ... | ['Aftercare', 'Bone Density', 'Breast Neoplasms', 'Breast Self-Examination', 'Cancer Survivors', 'Chemotherapy, Adjuvant', 'Female', 'Hematologic Tests', 'Humans', 'Magnetic Resonance Imaging', 'Mammography', 'Physical Examination', 'Practice Guidelines as Topic'] | 30,887,287 | [['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['G11.427.100'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.600.750.100', 'F01.145.488.700.100'], ['M01.860.350'], ['E02.186.170', 'E02.319.170'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of two fluorosis indices in the primary dentition of Tswana children. | Fluorosis of the primary dentition was determined in 146 children living in a hot, dry African village with a fluoride concentration in the drinking water of 0.98-2.7 ppm. The prevalence of fluorosis was compared using DEAN's (8) and THYLSTRUP & FEJERSKOV's (14) indices. The prevalence varied according to tooth type, b... | ['Botswana', 'Child', 'Child, Preschool', 'Female', 'Fluorosis, Dental', 'Humans', 'Infant', 'Male', 'South Africa', 'Tooth, Deciduous'] | 3,471,382 | [['Z01.058.290.175.230'], ['M01.060.406'], ['M01.060.406.448'], ['C07.793.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.058.290.175.735'], ['A14.549.167.860.700']] | ['Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Adjuvant ipilimumab in stage III melanoma: New landscape, new questions. | The recently reported significant prolongation of overall survival with ipilimumab as adjuvant in high-risk stage III melanoma patients represents an important event in the adjuvant treatment landscape. The European Organisation for Research and Treatment of Cancer 18071 trial demonstrated a 28% reduction in risk of de... | ['Antibodies, Monoclonal', 'CTLA-4 Antigen', 'Chemotherapy, Adjuvant', 'Disease-Free Survival', 'Humans', 'Immunologic Factors', 'Interferon-alpha', 'Ipilimumab', 'Lymph Node Excision', 'Melanoma', 'Neoplasm Staging', 'Skin Neoplasms'] | 27,816,830 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.465.782', 'D12.776.543.750.705.222.750', 'D23.050.301.264.894.158', 'D23.101.100.894.158'], ['E02.186.170', 'E02.319.170'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The outcome of 5-ALA-mediated photodynamic treatment in melanoma cells is influenced by vitamin C and heme oxygenase-1. | Photodynamic therapy (PDT) is an important clinical approach for cancer treatment. It involves the administration of a photosensitizer, followed by its activation with light and induction of cell death. The underlying mechanism is an increased production of reactive oxygen species (ROS) leading to oxidative stress, whi... | ['Aminolevulinic Acid', 'Antioxidants', 'Ascorbic Acid', 'Cell Line, Tumor', 'Cell Survival', 'Heme Oxygenase-1', 'Humans', 'Melanoma', 'Oxidative Stress', 'Photochemotherapy', 'Photosensitizing Agents', 'Protoporphyrins', 'Up-Regulation'] | 21,328,623 | [['D02.241.755.547.276', 'D12.125.262'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D08.811.682.690.708.410.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete oxidation of benzoate and 4-hydroxybenzoate by a new sulfate-reducing bacterium resembling Desulfoarculus. | A new sulfate-reducer "strain SAX" was isolated from an anaerobic marine sediment [Saxild, Denmark]. The isolate was a gram-negative, motile and non-spore-forming rod which sometimes appeared as a curved rod. Strain SAX differed from all described Desulfovibrio-, Desulfobotulus- and Desulfoarculus-species by the abilit... | ['Benzoates', 'Benzoic Acid', 'Biodegradation, Environmental', 'DNA, Bacterial', 'Desulfovibrio', 'Hydrogen-Ion Concentration', 'Microscopy, Electron, Scanning', 'Oxidation-Reduction', 'Parabens', 'Sodium Chloride', 'Sulfates', 'Temperature'] | 8,439,232 | [['D02.241.223.100', 'D02.455.426.559.389.127'], ['D02.241.223.100.120', 'D02.455.426.559.389.127.117'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D13.444.308.212'], ['B03.440.425.410.350', 'B03.660.125.144.500.875', 'B03.900.350'], ['G02.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G02.700', 'G03.2... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Homozygosity for the variant alpha-L-fucosidase trait and mucolipidosis III. | The variant alpha-L-fucosidase genotype, phenotypically observed as a low plasma level of alpha-L-fucosidase in healthy individuals, can modify the plasma expression of the primary genetic defect in mucolipidosis III. Three patients with clinical, radiological, and biochemical features of mucolipidosis III, had a norma... | ['Female', 'Genes, Recessive', 'Genetic Testing', 'Genetic Variation', 'Homozygote', 'Humans', 'Male', 'Mucolipidoses', 'alpha-L-Fucosidase'] | 3,997,153 | [['G05.360.340.024.340.415', 'G05.420.325'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['G05.365'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.198.371', 'C10.228.140.163.100.435.590', 'C16.320.565.189.435.590', 'C16.320.565.202.670', 'C... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Neural correlates of fast stimulus discrimination and response selection in top-level fencers. | Flexible adaptation of behaviour is highly required in some sports, such as fencing. In particular, stimulus discrimination and motor response selection and inhibition processes are crucial. We investigated the neural mechanisms responsible for fencers' fast and flexible behaviour recording event-related potentials (ER... | ['Adult', 'Behavior', 'Discrimination, Psychological', 'Electroencephalography', 'Evoked Potentials', 'Humans', 'Psychomotor Performance', 'Reaction Time', 'Sports', 'Visual Perception'] | 17,018,246 | [['M01.060.116'], ['F01.145'], ['F02.463.593.257'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['I03.450.642.845'], ['F02.463.593... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Angioscopic evaluation of an endoluminal aortic graft: the first clinical experience. | PURPOSE: Balloon aortoscopy has been described for viewing aortic endoluminal anatomy and guiding aortic stent placement in animals. We report the first clinical use of this technique to visually inspect the proximal portion of a 1-year-old endovascular aortic graft, its proximal fixation stent, and its relationship to... | ['Angioscopy', 'Aorta', 'Aortic Aneurysm, Abdominal', 'Blood Vessel Prosthesis', 'Female', 'Humans', 'Middle Aged', 'Postoperative Period', 'Stents'] | 9,234,139 | [['E01.370.370.065', 'E01.370.388.250.035', 'E04.100.814.529.500', 'E04.502.250.035', 'E04.502.382.500'], ['A07.015.114.056'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E07.695.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.750', 'N02.421.585.753.750'], ['E07.695.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. III. Structural elucidation of plipastatins. | Plipastatins are new inhibitors of phospholipase A2 produced by Bacillus cereus BMG302-fF67. Structures of the plipastatins have been determined by UV, mass and NMR spectrometries and chemical degradation. The carboxyl group of the C-terminal L-isoleucine of plipastatinic acid has been shown to form a lactone linkage w... | ['Anti-Bacterial Agents', 'Bacillus cereus', 'Chemical Phenomena', 'Chemistry', 'Fatty Acids', 'Lactones', 'Magnetic Resonance Spectroscopy', 'Oligopeptides', 'Peptides, Cyclic', 'Phospholipases', 'Phospholipases A', 'Phospholipases A2', 'Spectrophotometry, Infrared', 'Spectrophotometry, Ultraviolet'] | 3,089,999 | [['D27.505.954.122.085'], ['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['G02'], ['H01.181'], ['D10.251'], ['D02.540'], ['E05.196.867.519'], ['D12.644.456'], ['D04.345.566', 'D12.644.641'], ['D08.811.277.352.100.680',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Bladder cancer in neurogenic patients: A retrospective study of management and follow-up]. | INTRODUCTION: The prevalence of bladder cancer (BC) in neurological patients seems to be similar to that of the general population. However, they are more aggressive with a higher rate of muscle-invasive forms and squamous cells carcinomas. The aim of the current study was to report etiologies, management and outcomes ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Urinary Bladder Neoplasms', 'Urinary Bladder, Neurogenic'] | 29,174,817 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lumping and splitting: the health policy agenda in India. | India's health system was designed in a different era, when expectations of the public and private sectors were quite different. India's population is also undergoing transitions in the demographic, epidemiologic and social aspects of health. Disparities in life expectancy, disease, access to health care and protection... | ['Delivery of Health Care', 'Health Expenditures', 'Health Policy', 'Health Status Indicators', 'Health Transition', 'Humans', 'India'] | 12,917,266 | [['N04.590.374', 'N05.300'], ['N03.219.151.450', 'N05.300.385'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['I01.240.600.400', 'N01.224.625.400', 'N06.850.505.400.700.400', 'N06.850.650'], ['B01.0... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[A case of inverted papilloma of the prostatic urethra]. | A 59-year-old male with a complaint of gross hematuria was found to have a pedunculated and non-papillary tumor on the prostatic urethra. The tumor was resected transurethrally. The pathological finding was inverted papilloma. Although the majority of the cases of inverted papilloma have been found in the bladder, we r... | ['Humans', 'Male', 'Middle Aged', 'Papilloma, Inverted', 'Urethral Neoplasms'] | 14,518,389 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.470.700.600.610'], ['C04.588.945.947.945', 'C12.758.820.937', 'C12.777.767.601', 'C13.351.937.820.890', 'C13.351.968.767.601']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Purification and characterization of pyruvate decarboxylase from Sarcina ventriculi. | Pyruvate decarboxylase from the obligate anaerobe Sarcina ventriculi was purified eightfold. The subunit Mr was 57,000 +/- 3000 as estimated from SDS-PAGE, and the native Mr estimated by gel filtration on a Superose 6 column was 240,000, indicating that the enzyme is a tetramer. The Mr values are comparable to those fo... | ['Amino Acid Sequence', 'Chlorides', 'Enzyme Activation', 'Glyoxylates', 'Kinetics', 'Molecular Sequence Data', 'Molecular Weight', 'Protein Binding', 'Pyruvate Decarboxylase', 'Saccharomyces cerevisiae', 'Sarcina', 'Zinc', 'Zinc Compounds'] | 1,588,311 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G02.111.263', 'G03.328'], ['D02.241.152.367'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['G02.494'], ['G02.111.679', 'G03.808'], ['D08.811.520.224.125.750'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['B03.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus. | The crystal structure of GST Nu2-2 (HpolGSTN2-2) from the model hookworm nematode Heligmosomoides polygyrus has been solved by the molecular replacement method and refined to a resolution of 1.71 A, providing the first structural data from a class of nematode-specific GSTs. By structural alignment with two Sigma class ... | ['Animals', 'Binding Sites', 'Crystallography, X-Ray', 'Enzyme Inhibitors', 'Glutathione Transferase', 'Heligmosomatoidea', 'Humans', 'Ligands', 'Models, Molecular', 'Protein Structure, Secondary', 'Strongylida Infections'] | 16,189,827 | [['B01.050'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['D27.505.519.389'], ['D08.811.913.225.500'], ['B01.050.500.500.294.400.968.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['E05.599.595'], ['G02.111.570.820.709.600'], ['C01.610.335.508.700.775']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Static Hot Air and Infrared Rays Roasting are Efficient Methods for Aflatoxin Decontamination on Hazelnuts. | Aflatoxins are a group of secondary metabolites produced by members of Aspergillus Section Flavi that are dangerous to humans and animals. Nuts can be potentially contaminated with aflatoxins, often over the legal threshold. Food processes, including roasting, may have different effects on mycotoxins, and high temperat... | ['Aflatoxins', 'Air', 'Corylus', 'Decontamination', 'Fatty Acids', 'Food Contamination', 'Food Handling', 'Hot Temperature', 'Infrared Rays', 'Nuts'] | 28,230,792 | [['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['G16.500.275.063.150', 'N06.230.300.100.150'], ['B01.650.940.800.575.912.250.859.750.200.875'], ['N06.850.780.325'], ['D10.251'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.200'], ['G01.906.595.543', 'G16.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Reface, remodel, or rebuild your dental office. | Upgrades to a dental practice can range from a minor facelift to all new construction. Consulting a certified public accountant is important to properly account for all the various assets that go into a new office so the tax benefits from each can be optimized. After all the dust has settled, practitioners will be able... | ['Accounting', 'California', 'Capital Financing', 'Consultants', 'Dental Offices', 'Electric Power Supplies', 'Facility Design and Construction', 'Humans', 'Practice Management, Dental', 'Taxes'] | 20,806,692 | [['N03.219.463.030'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N03.219.463.085'], ['M01.120'], ['N02.278.192.377'], ['E07.305.124'], ['J01.086.339', 'N02.278.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.758.708.300'], ['N03.219.900']] | ['Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Calcium binding activity of the epidermal growth factor-like domains of the apicomplexan microneme protein EtMIC4. | Microneme proteins are secreted from apicomplexan parasites during invasion of host cells and they play crucial roles in parasite-host cell adhesion. EtMIC4 is a 240 kDa transmembrane protein from Eimeria tenella that contains 31 tandemly arranged epidermal growth factor (EGF), like repeats within its extracellular dom... | ['Amino Acid Sequence', 'Animals', 'Calcium', 'Cell Adhesion Molecules', 'Circular Dichroism', 'Eimeria tenella', 'Epidermal Growth Factor', 'Mass Spectrometry', 'Molecular Sequence Data', 'Peptide Hydrolases', 'Protein Binding', 'Protein Conformation', 'Protein Structure, Tertiary', 'Protozoan Proteins'] | 16,024,103 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['E05.196.867.151'], ['B01.043.075.189.250.250.250.250'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Experiences with computer navigated total knee arthroplasty. | The successful outcome of total knee arthroplasty (TKA) is very much dependent on precise positioning of the components. Inaccuracy may result in complaints as well as in early mechanical failure. Between March 2003 and September 2005, 69 TKA procedures were performed by the computer navigated technique. The postoperat... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Surgery, Computer-Assisted'] | 17,115,156 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.749']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A peer learning intervention targeting newly graduated nurses: A feasibility study with a descriptive design based on the Medical Research Council framework. | AIMS: The aim of this study was to describe the feasibility of a peer learning intervention targeting newly graduated nurses. Feasibility was tested concerning consistency of the theoretical description of peer learning with empirical findings in a new context, compliance and acceptability, as well as usability of a qu... | ['Adaptation, Psychological', 'Adult', 'Education, Nursing, Baccalaureate', 'Feasibility Studies', 'Female', 'Humans', 'Inservice Training', 'Male', 'Nursing Staff', 'Peer Group', 'Stress, Psychological', 'Surveys and Questionnaires', 'Young Adult'] | 29,193,242 | [['F01.058'], ['M01.060.116'], ['I02.358.462.316'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['M01.526.485.680', 'N02.360.680'], ['F01.829.316.483'], ['F01.145.126.990', 'F02.830.900'], ['E05.318.308.980', 'N05.715.36... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The role of donor-recipient relationship in long-term outcomes of living donor renal transplantation. | BACKGROUND: Graft failure related to acute and chronic rejection remains an important problem in transplantation. An association has been reported between microchimerism and the development of tolerance. Since it has been established that cells of fetal origin can be found in maternal tissues long after parturition, an... | ['Adolescent', 'Adult', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Kidney Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Nuclear Family', 'Parent-Child Relations', 'Research Design', 'Retrospective Studies', 'Siblings', 'Survival Analysis', 'Time Factors'] | 18,497,690 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.898.656'], ['M01.060.116.630'], ['F01.829.263.500', 'I01.880.853.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Conditioned reactions and mediator-humoral shifts during neurotization in a probabilistic pain reinforcement situation]. | Substitution of regular partial reinforcement for random one (in both cases the reinforcement frequency was 50%) acted in some dogs as a neurotizing factor: they showed unrest, stable defensive reflexes disappeared, corresponding changes were observed in vegetative reactions. At the same time activation of the sympatho... | ['Acetylcholine', 'Animals', 'Conditioning, Classical', 'Dogs', 'Epinephrine', 'Humans', 'Motivation', 'Motor Activity', 'Neurotic Disorders', 'Norepinephrine', 'Pain', 'Probability', 'Reinforcement Schedule', 'Sound'] | 569,945 | [['D02.092.211.111'], ['B01.050'], ['F02.463.425.179.308'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Interplay between DNA replication and recombination in prokaryotes. | The processes of DNA replication and recombination are intertwined at many different levels. In diverse systems, extensive DNA replication can be triggered by genetic recombination, with assembly of a replication complex onto a D-loop recombination intermediate. This and related pathways of replisome assembly allow the... | ['Bacteriophage T4', 'DNA Repair', 'DNA Replication', 'DNA, Bacterial', 'Escherichia coli', 'Recombination, Genetic', 'SOS Response, Genetics'] | 15,792,496 | [['B04.123.150.500.350', 'B04.123.205.891.200', 'B04.280.090.500.350'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.728'], ['G02.111.222.830', 'G05.219.830']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoscope-assisted suction extraction of lipomas. | The blunt technique of suction-assisted lipectomy partially evolved while proving to be an efficient, albeit blind, method for the removal of lipomas. Larger or poorly encapsulated tumors were acknowledged to be at a greater risk for recurrence probably because of an unrecognized residua. Just as liposuction has enhanc... | ['Endoscopy', 'Humans', 'Lipectomy', 'Lipoma', 'Soft Tissue Neoplasms'] | 7,702,298 | [['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.530', 'E02.650.500.062.937', 'E04.062.937', 'E04.680.450'], ['C04.557.450.550.400'], ['C04.588.839']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fibrinogen concentrate substitution therapy for obstetric hemorrhage complicated by coagulopathy. | AIM: The aim of this study was to assess the efficacy and safety of fibrinogen concentrate therapy for women with obstetric hemorrhage complicated by dilutional or consumptive coagulopathy by retrospectively reviewing the medical records of relevant patients from a single tertiary center.MATERIAL AND METHODS: Eighteen ... | ['Adult', 'Blood Coagulation Disorders', 'Blood Coagulation Factors', 'Female', 'Fibrinogen', 'Hemostatics', 'Humans', 'Pregnancy', 'Pregnancy Complications, Hematologic', 'Retrospective Studies', 'Uterine Hemorrhage'] | 23,278,972 | [['M01.060.116'], ['C15.378.100'], ['D12.776.124.125', 'D23.119'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D27.505.954.502.270.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703.667', 'C15.378.785'], ['E05.318.372.500.500.500', 'E05.318.372... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase. | A direct link between receptor glycosylation and activation following natural ligand interaction has not been observed. Here, we discover a membrane sialidase-controlling mechanism that depends on ligand binding to its receptor to induce enzyme activity which targets and desialylates the receptor and, consequently, cau... | ['Animals', 'Asialoglycoproteins', 'Brain-Derived Neurotrophic Factor', 'Cerebral Cortex', 'Embryo, Mammalian', 'Enzyme Activation', 'Female', 'Membrane Proteins', 'Mice', 'Nerve Growth Factors', 'Neuraminidase', 'Neurons', 'PC12 Cells', 'Pregnancy', 'Protein Binding', 'Rats', 'Receptor Protein-Tyrosine Kinases', 'Rece... | 16,971,381 | [['B01.050'], ['D12.776.395.140'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A08.186.211.200.885.287.500'], ['A16.254'], ['G02.111.263', 'G03.328'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.276.860', 'D12.776.467.860', 'D12.776.631.600', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pattern of recognition of Neospora caninum tachyzoite antigens by naturally infected pregnant cattle and aborted foetuses. | Different aspects of Neospora tachyzoite antigen recognition by Neospora-infected heifers and cows and aborted foetuses were studied. The pattern of antigen recognition and the relationship between IFAT titres and number of Neospora antigens detected, were evaluated. In addition, the tachyzoite antigens involved in the... | ['Aborted Fetus', 'Abortion, Veterinary', 'Animals', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Blotting, Western', 'Cattle', 'Cattle Diseases', 'Coccidiosis', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Fluorescent Antibody Technique, Indirect', 'Infectious Disease Transmission, Vertical', 'Kinetics', 'Mol... | 12,072,210 | [['A16.378.099'], ['C13.703.039.422', 'C22.021'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.050.150.900.649.313.500.380.271'], ['C... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Differential effects of the tumor necrosis factor alpha-blocker infliximab and etanercept on immunocompetent cells in vitro. | The tumor necrosis factor-alpha (TNFá) antagonists infliximab or etanercept are used in the management of chronic inflammatory disorders but have differences in clinical activity. Here we show that both have different effects on immunocompetent cells in vitro. Peripheral blood mononuclear cells (PBMC) from 20 healthy d... | ['Adult', 'Antibodies, Monoclonal', 'Cell Proliferation', 'Cytokines', 'Cytotoxicity, Immunologic', 'Dose-Response Relationship, Drug', 'Etanercept', 'Female', 'Flow Cytometry', 'Humans', 'Immunoglobulin G', 'Infliximab', 'Macrophages', 'Male', 'Natural Killer T-Cells', 'Receptors, Tumor Necrosis Factor', 'Tumor Necros... | 21,704,732 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.287'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.541.500.697.624', 'D12.776.124.486.485.538.500.62... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Feasibility of an injectable and in situ | Objective: To introduce an injectable and in situ gelling gelatin hydrogel, and to explore the possibility as a carrier for demineralized bone matrix (DBM) powder delivery.Methods: First, thiolated gelatin was prepared and the thiol content was determined by Ellman method, and then the injectable and in situ gelling ge... | ['Animals', 'Biocompatible Materials', 'Bone Matrix', 'Gelatin', 'Gels', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Rats'] | 29,806,258 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A10.165.265.166'], ['D12.776.860.476'], ['D20.280.320', 'D26.255.165.320'], ['D02.033.455.250.700.485', 'D05.750.219.500', 'D05.750.741.485', 'D20.280.320.609.500', 'D25.720.532.500', 'D25.720.741.485', 'D26.255.165.320.375.375', 'J01.637.051.720.584.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Specifics of anesthesia in extensive liver resection]. | There were analyzed the results of anesthesiological securing while performance of extensive hepatic resection in 46 patients (extended rite-sided--in 21, left-sided--in 22, mesohepatectomy--in 3) with preservation of 20-40% of the organ volume, including preoperative preparation, analgesia and intensive therapy after ... | ['Anesthesia, General', 'Female', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Postoperative Complications'] | 15,154,244 | [['E03.155.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['C23.550.767']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Joint TGF-â type II receptor-expressing cells: ontogeny and characterization as joint progenitors. | TGF-â type II receptor (Tgfbr2) signaling plays an essential role in joint-element development. The Tgfbr2(PRX-1KO) mouse, in which the Tgfbr2 is conditionally inactivated in developing limbs, lacks interphalangeal joints and tendons. In this study, we used the Tgfbr2-â-Gal-GFP-BAC mouse as a LacZ/green fluorescent pro... | ['Animals', 'Antigens, Differentiation', 'Cartilage, Articular', 'Cell Proliferation', 'Cells, Cultured', 'Female', 'Foot Joints', 'Forelimb', 'Gene Expression', 'Gene Expression Regulation, Developmental', 'Male', 'Mice', 'Mice, Transgenic', 'Protein-Serine-Threonine Kinases', 'Receptor, Transforming Growth Factor-bet... | 23,231,014 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A02.835.583.378'], ['A13.395'], ['G05.297'], ['G05.308.310'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vinblastine inhibits the angiogenic response induced by adrenomedullin in vitro and in vivo. | Adrenomedullin (ADM) is protumorigenic by stimulating tumor cell growth and angiogenesis. In this context, ADM is identified as a novel target for antiangiogenic therapy. In this study, we addressed the possibility that vinblastine (VBL), as demonstrated in other experimental conditions, may act as an angiostatic molec... | ['Adrenomedullin', 'Animals', 'Antineoplastic Agents, Phytogenic', 'Chick Embryo', 'Growth Substances', 'Neovascularization, Pathologic', 'Peptides', 'Vinblastine'] | 14,508,526 | [['D06.472.699.077', 'D12.644.548.017'], ['B01.050'], ['D27.505.954.248.179'], ['A13.350.150', 'A16.331.200'], ['D27.505.696.377'], ['C23.550.589.500'], ['D12.644'], ['D03.132.436.681.827.650', 'D03.633.100.473.402.681.827.650', 'D03.633.100.496.500.500.681.827.650']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Limited agreement between current and long-term asthma control in children: the PACMAN cohort study. | BACKGROUND: Several studies have shown that predictors of asthma treatment outcomes differ depending on the definition of the outcome chosen. This provides evidence that different outcomes studied may reflect distinct aspects of asthma control. To assess predictors of asthma control, we need firm outcome phenotypes. Th... | ['Administration, Inhalation', 'Adrenal Cortex Hormones', 'Anti-Asthmatic Agents', 'Asthma', 'Child', 'Child, Preschool', 'Cohort Studies', 'Disease Progression', 'Drug Administration Schedule', 'Emergency Medical Services', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Netherlands', 'Seasons', 'Surveys and Questio... | 21,749,459 | [['E02.319.267.050'], ['D06.472.040'], ['D27.505.954.796.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.656'], ['E02.319.283'], ['N02.421.297'], ['E05.318.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
"Atherogenic index of plasma" (log10 triglyceride/high-density lipoprotein-cholesterol) predicts high blood pressure, diabetes, and vascular events. | OBJECTIVES: To determine the association of atherogenic index of plasma (AIP), the logarithm of molar ratio of triglyceridemia to high-density lipoprotein cholesterol (TG/HDL-cholesterol) with cardiometabolic disorders was investigated in a sample of the Turkish population.METHODS: A total of 2676 middle-aged adults we... | ['Adult', 'Aged', 'Aged, 80 and over', 'Apolipoproteins B', 'Atherosclerosis', 'C-Reactive Protein', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Hypertension', 'Inflammation Mediators', 'Linear Models', 'Male', 'Middle Aged', 'Obesity', 'Prospective Studies', 'Risk Factors'... | 21,122,635 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['C14.907.137.126.307'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evidence-based and unlicensed indications for proton pump inhibitors and patients' preferences for discontinuation: a pilot study in a sample of Italian community pharmacies. | WHAT IS KNOWN AND OBJECTIVE: Despite the widespread use of proton pump inhibitors (PPIs), little is known about the appropriateness of treatment according to the indications reported by patients and their involvement in the process of treatment discontinuation. In patients who are unlikely to benefit, the medication sh... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Drug Utilization', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Patient Preference', 'Pharmacies', 'Pilot Projects', 'Proton Pump Inhibitors', 'Young Adult'] | 26,931,180 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.452.706.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['F01.100.150.750.625.500', 'F01.145.488.887.625.500', 'N04.452.822.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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