Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Parallel transmission RF pulse design for eddy current correction at ultra high field. | Multidimensional spatially selective RF pulses have been used in MRI applications such as B₁ and B₀ inhomogeneities mitigation. However, the long pulse duration has limited their practical applications. Recently, theoretical and experimental studies have shown that parallel transmission can effectively shorten pulse du... | ['Algorithms', 'Computer Simulation', 'Humans', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Radio Waves', 'Software', 'Whole Body Imaging'] | 22,789,452 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E07.671'], ['G01.358.500.505.810', 'G01.750.250.810', 'G01.750.770.721'], ['L01.224.900'], ['E01.370.350.925', 'E05.979']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Paraoxonase 1 activity in chylomicrons and VLDL: the effect of type 2 diabetes and meals rich in saturated fat and oleic acid. | Paraoxonase 1 (PON 1) has antioxidant and cardioprotective properties and is abnormally low in type 2 diabetic serum. This study aimed to determine the effect of type 2 diabetes and meals rich in saturated fat and oleic acid on PON1 activity in chylomicrons and very low density lipoproteins (VLDL). PON1 arylesterase ac... | ['Aged', 'Aryldialkylphosphatase', 'Chylomicrons', 'Cross-Over Studies', 'Diabetes Mellitus, Type 2', 'Dietary Fats', 'Female', 'Humans', 'Lipoproteins, VLDL', 'Male', 'Middle Aged', 'Oleic Acid'] | 22,160,450 | [['M01.060.116.100'], ['D08.811.277.352.660.500'], ['D10.532.183', 'D12.776.521.242'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C18.452.394.750.149', 'C19.246.300'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.599', 'D12.776.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Pelvic exenteration for carcinoma of the cervix. | Pelvic exenteration for carcinoma of the cervix uteri carries a 15 per cent operative mortality and a 23.3 per cent five-year survival. Total exenteration, not anterior exenteration or modified exenteration, is the operation of choice in the heavily irradiated patient. The criteria for operability are proof of persiste... | ['Combined Modality Therapy', 'Female', 'Humans', 'Middle Aged', 'Pelvic Exenteration', 'Postoperative Complications', 'Retrospective Studies', 'Survival Rate', 'Uterine Cervical Neoplasms'] | 17,926,376 | [['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.584'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['E05.318.308.985.550.900'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exploration of the Brn4-regulated genes enhancing adult hippocampal neurogenesis by RNA sequencing. | Adult hippocampal neurogenesis is essential for learning and memory, and its dysfunction is involved in neurodegenerative diseases. However, the molecular mechanisms underlying adult hippocampal neurogenesis are still largely unknown. Our previous studies indicated that the transcription factor Brn4 was upregulated and... | ['Animals', 'Gene Expression Regulation', 'High-Throughput Nucleotide Sequencing', 'Hippocampus', 'Mice', 'Mice, Knockout', 'Nerve Tissue Proteins', 'Neurogenesis', 'POU Domain Factors', 'Rats', 'Rats, Sprague-Dawley'] | 28,213,929 | [['B01.050'], ['G05.308'], ['E05.393.760.319'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['D12.776.631'], ['G04.152.912', 'G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Steroid sulfatase expression in human placenta: immunocytochemistry and in situ hybridization study. | Steroid sulfatase (STS), an important enzyme in the pathway of estrogen synthesis from sulfated steroid precursors, was localized to the syncytial trophoblast of human placentas during different periods of pregnancy by using a mouse monoclonal antibody and immunocytochemical techniques. Preembedding immunoelectron micr... | ['Arylsulfatases', 'Female', 'Gene Expression', 'Humans', 'Immunohistochemistry', 'Nucleic Acid Hybridization', 'Placenta', 'Pregnancy', 'RNA, Messenger', 'Steryl-Sulfatase', 'Sulfatases', 'Trophoblasts'] | 2,347,893 | [['D08.811.277.352.827.070'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
C3 Glomerulonephritis With Multiple Mutations in Complement Factor H. | Complement C3 glomerulopathy refers to a disease process in which abnormal control of complement activation or degradation results in predominant C3 fragment deposition within the glomerulus and causes glomerular damage. Abnormal control of the complement alternative pathway is a well-established risk factor for the oc... | ['Adult', 'Atypical Hemolytic Uremic Syndrome', 'Complement Activation', 'Complement C3', 'Complement Factor H', 'Complement Pathway, Alternative', 'Female', 'Glomerulonephritis', 'Humans', 'Iran', 'Kidney Glomerulus', 'Mutation'] | 30,595,568 | [['M01.060.116'], ['C12.777.419.936.463.500', 'C13.351.968.419.936.463.500', 'C15.378.071.141.610.500', 'C15.378.140.855.925.500.500'], ['G12.274'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274.920.325.200', 'D12.776.124.790.223.200', 'D12.776.377.715.182.200'], ['G12.274.695'], ['C12.777.4... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Identification of a conserved archaeal RNA polymerase subunit contacted by the basal transcription factor TFB. | Archaea possess two general transcription factors that are required to recruit RNA polymerase (RNAP) to promoters in vitro. These are TBP, the TATA-box-binding protein and TFB, the archaeal homologue of TFIIB. Thus, the archaeal and eucaryal transcription machineries are fundamentally related. In both RNAP II and archa... | ['Amino Acid Sequence', 'Archaea', 'Archaeal Proteins', 'DNA-Directed RNA Polymerases', 'Molecular Sequence Data', 'Nuclear Proteins', 'Plasmids', 'Point Mutation', 'Promoter Regions, Genetic', 'Protein Binding', 'Protein Structure, Tertiary', 'Sequence Homology, Amino Acid', 'Transcription Factor TFIIB', 'Transcriptio... | 11,606,563 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B02'], ['D12.776.090'], ['D08.811.913.696.445.735.270'], ['L01.453.245.667'], ['D12.776.660'], ['G05.360.600'], ['G05.365.590.675'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.610... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anti-anxiety activity of successive extracts of Angelica archangelica Linn. on the elevated T-maze and forced swimming tests in rats. | OBJECTIVE: Angelica archangelica Linn. is widely used in food and liquor preparations and also in Kashmiri folk medicine to reduce anxiety. We evaluated the anxiolytic effect of successive extracts of A. archangelica linn. (SAE) on rats tested in the elevated T-maze test (an animal model of generalized anxiety) at dose... | ['Angelica archangelica', 'Animals', 'Anti-Anxiety Agents', 'Anxiety', 'Female', 'Humans', 'Male', 'Maze Learning', 'Motor Activity', 'Plant Extracts', 'Rats', 'Rats, Wistar', 'Swimming'] | 23,297,567 | [['B01.650.940.800.575.912.250.075.088.077'], ['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['F01.470.132'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.874.500'], ['F01.145.632', 'G11.427.410.698'], ['D20.215.784.500', 'D26.667'], ['B01.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Use of etomidate in patients with heart failure undergoing noncardiac surgery. | BACKGROUND: Patients with symptomatic and asymptomatic heart failure undergoing noncardiac surgery may benefit from the haemodynamic profile of etomidate. However, the safety of etomidate in this population is unknown. We examined anaesthesiologist variation in etomidate use and assessed its safety using an instrumenta... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Etomidate', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Middle Aged', 'Retrospective Studies', 'Surgical Procedures, Operative', 'Young Adult'] | 32,807,381 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.129.308.265'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypoxia induces different responses of striatal high- and low- affinity dopamine uptake sites. | The dopamine (DA) uptake over a concentration range from 0.03 to 100 microM was studied in S1 fractions of the rat striatum prepared from control rats and those exposed for 14 h to hypobaric hypoxia. The uptake exhibited non-Michaelis-Menten kinetics, which were evaluated by applying an equation assuming two transport ... | ['Animals', 'Corpus Striatum', 'Hypoxia, Brain', 'In Vitro Techniques', 'Kinetics', 'Male', 'Rats', 'Rats, Wistar', 'Receptors, Dopamine', 'Subcellular Fractions'] | 8,466,591 | [['B01.050'], ['A08.186.211.200.885.287.249.487'], ['C10.228.140.624', 'C23.888.852.079.797'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D12.776.543.750.670.300.400', 'D12.776.543.750.695.150.400', 'D12.776.543.750.720.33... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The clinical significance of 5% change in vital capacity in patients with idiopathic pulmonary fibrosis: extended analysis of the pirfenidone trial. | BACKGROUND: Our phase III clinical trial of pirfenidone for patients with idiopathic pulmonary fibrosis (IPF) revealed the efficacy in reducing the decline of vital capacity (VC) and increasing the progression-free survival (PFS) time by pirfenidone. Recently, marginal decline in forced VC (FVC) has been reported to be... | ['Aged', 'Disease Progression', 'Disease-Free Survival', 'Double-Blind Method', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Japan', 'Kaplan-Meier Estimate', 'Lung', 'Middle Aged', 'Pyridones', 'Respiratory System Agents', 'Risk Assessment', 'Risk Factors', 'Time Factors', 'Treatment Outcome', 'Vital Capacity'] | 21,756,364 | [['M01.060.116.100'], ['C23.550.291.656'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Constitutive expression of PPARã inhibits proliferation and migration of gastric cancer cells and down-regulates Wnt/â-Catenin signaling pathway downstream target genes TERT and ENAH. | BACKGROUND: Peroxisome proliferator-activated receptor ã (PPARã) is a member of the PPAR nuclear hormone receptor superfamily, which plays a crucial role in carcinogenesis. Wnt/â-Catenin signaling pathway has been well certified to contribute to the progression of gastric malignancies. â-Catenin mediates transcriptiona... | ['Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Down-Regulation', 'Humans', 'Microfilament Proteins', 'PPAR gamma', 'Stomach Neoplasms', 'Telomerase', 'Wnt Proteins', 'beta Catenin'] | 26,956,036 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.730', 'D12.776.220.525'], ['D12.776.826.239.588'], ['C04.588.274.476.767', 'C06.301.371.767',... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the primary structure of 14 proteins from the large subunit of Escherichia coli ribosomes with an improved protein sequenator and with mass spectrometry. | Fourteen proteins from the large subunit of Escherichia coli ribosomes were analyzed in an improved sequenator. In addition to our previously described modifications of a Beckman sequenator, new valves which work free of a dead volume were constructed. By this and the previous improvements (e.g., a new vacuum system wi... | ['Amino Acid Sequence', 'Amino Acids', 'Autoanalysis', 'Bacterial Proteins', 'Chromatography, Gas', 'Chromatography, Thin Layer', 'Escherichia coli', 'Hydrolysis', 'Mass Spectrometry', 'Protein Conformation', 'Ribosomes'] | 1,107,676 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['E05.059'], ['D12.776.097'], ['E05.196.181.349'], ['E05.196.181.400.537'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.380'], ['E05.196.566'], ['G02.111.570.820.709'], ['A11.284.430.214.190.875.811']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of theophylline on the apical sodium and chloride permeabilities of amphibian skin. | 1. The effects of theophylline (1 mmol/l) on the sodium transport (short-circuit current, Isc) and transepithelial conductance (Gtotal) through toad (Bufo viridis) and frog (Rana temporaria and Rana esculenta) skin were investigated. 2. In toad skin incubated with nitrate Ringer solution on the apical side, theophyllin... | ['Amphibians', 'Animals', 'Biological Transport', 'Bufonidae', 'Cell Membrane Permeability', 'Chlorides', 'In Vitro Techniques', 'Ion Channels', 'Rana esculenta', 'Rana temporaria', 'Skin', 'Sodium', 'Theophylline'] | 2,457,697 | [['B01.050.150.900.090'], ['B01.050'], ['G03.143'], ['B01.050.150.900.090.180.210'], ['G03.143.335', 'G04.175'], ['D01.210.450.150', 'D01.248.497.158.215'], ['E05.481'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['B01.050.150.900.090.180.708.240'], ['B01.050.150.900.090.180.708.420'], ['A17... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of CCDC6 as a novel biomarker for the clinical use of PARP1 inhibitors in malignant pleural mesothelioma. | OBJECTIVES: CCDC6 (coiled-coil domain containing 6) is a player of the HR response to DNA damage and has been predicted to interact with BAP1, another HR-DNA repair gene highly mutated in Malignant Pleural Mesothelioma (MPM), an aggressive cancer with poor prognosis. CCDC6 levels are modulated by the deubiquitinase USP... | ['Apoptosis', 'Biomarkers', 'Cell Line, Tumor', 'Cytoskeletal Proteins', 'DNA Damage', 'DNA Repair', 'Humans', 'Immunohistochemistry', 'Lung Neoplasms', 'Mesothelioma', 'Mesothelioma, Malignant', 'Mutation', 'Poly (ADP-Ribose) Polymerase-1', 'Poly(ADP-ribose) Polymerase Inhibitors', 'Tumor Suppressor Proteins', 'Ubiqui... | 31,447,003 | [['G04.146.954.035'], ['D23.101'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.220'], ['G05.200'], ['G02.111.222', 'G05.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.5... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of cultivation for snail control on schistosomiasis in Changsha urban section of Xiangjiang River]. | OBJECTIVE: To study a reliable, friendly environmental and sustainable Oncomelania snail control method in marshlands of the Xiangjiang River.METHODS: According to the special characteristics of the marshlands of the Xiangjiang River, smoothing and cultivating in beaches were applied for snail control. In sections with... | ['Animals', 'China', 'Humans', 'Mice', 'Pest Control', 'Rivers', 'Schistosoma japonicum', 'Schistosomiasis japonica', 'Snails', 'Urban Health'] | 22,379,824 | [['B01.050'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['N06.850.780.200.650'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['B01.050.500.500.736.715.770.680.570'], ['C01.610.335.865.859.521', 'C01.920.922.521'], ['B01.050.500.644.... | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Patterns of Red and Processed Meat Consumption and Risk for Cardiometabolic and Cancer Outcomes: A Systematic Review and Meta-analysis of Cohort Studies. | This article has been corrected. The original version (PDF) is appended to this article as a Supplement.Background: Studying dietary patterns may provide insights into the potential effects of red and processed meat on health outcomes.Purpose: To evaluate the effect of dietary patterns, including different amounts of r... | ['Cardiovascular Diseases', 'Diet', 'Humans', 'Meat Products', 'Neoplasms', 'Red Meat'] | 31,569,217 | [['C14'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.600.500', 'J02.500.600.500'], ['C04'], ['G07.203.300.600.813', 'J02.500.600.813']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A new paradigm for electrostatic catalysis of radical reactions in vitamin B12 enzymes. | The catalytic power of enzymes containing coenzyme B(12) cofactor has been, in some respects, the "last bastion" for the strain hypothesis. The present work explores the origin of this effect by using simulation methods that overcome the sampling difficulties of previous energy minimization studies. It is found that th... | ['Catalysis', 'Cobamides', 'Computer Simulation', 'Intramolecular Transferases', 'Models, Molecular', 'Molecular Structure', 'Static Electricity'] | 17,517,615 | [['G02.130'], ['D03.383.129.578.840.437.777.270', 'D03.633.400.909.437.777.270', 'D04.345.783.437.777.270', 'D08.211.175'], ['L01.224.160'], ['D08.811.399.520'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G01.358.500.249.820']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Frequency of maternal mortality and morbidity in pregnancy-induced hypertension. | BACKGROUND: Pregnancy-induced hypertension (PIH) is defines as hypertension in pregnancy, and is sustained blood pressure >140 mm Hg systolic or 90 mm Hg diastolic. Objective of this study was to see the maternal outcome in terms of morbidity and mortality in PIH.METHODS: This descriptive study was conducted in Obstetr... | ['Adult', 'Female', 'Humans', 'Hypertension, Pregnancy-Induced', 'Maternal Mortality', 'Pakistan', 'Pregnancy', 'Risk Factors'] | 23,472,415 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.395', 'C14.907.489.480'], ['E05.318.308.985.550.500', 'N01.224.935.698.653', 'N06.850.505.400.975.550.500', 'N06.850.520.308.985.550.500'], ['Z01.252.245.723'], ['G08.686.784.769'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.3... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The effect of histamine on the adhesion of endothelial cells to eosinophils]. | Recent studies have revealed that eosinophils and eosinophil-derived mediators strongly contribute to the onset of nasal swelling and nasal hyperreactivity. The effect of histamine on the adhesion of endothelial cells to 35S-labeled eosinophils and on eosinophil transendothelial migration was investigated. Human microv... | ['Adolescent', 'Adult', 'Cell Adhesion', 'Cells, Cultured', 'Child', 'Endothelium, Vascular', 'Eosinophils', 'Histamine', 'Humans'] | 8,851,334 | [['M01.060.057'], ['M01.060.116'], ['G04.022'], ['A11.251'], ['M01.060.406'], ['A07.015.700.500', 'A10.272.491.355'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Male factors and the likelihood of pregnancy in infertile couples. II. Study of clinical characteristics--practical consequences. | A prospective study of 394 infertile men was conducted over 3 years following a primary semen analysis. Simple comparisons between the groups of men whose partners conceived and those that did not, showed that the mean duration of infertility in the primary infertile group was significantly shorter when a pregnancy was... | ['Age Factors', 'Alcohol Drinking', 'Analysis of Variance', 'Female', 'Humans', 'Infertility, Male', 'Male', 'Pregnancy', 'Prognosis', 'Prospective Studies', 'Smoking', 'Sperm Motility', 'Spermatozoa'] | 3,235,208 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.317.269'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['G08.686.784.769'], ['E01.789'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of whole-body road traffic vibration in building. | Level fluctuating vibration has been evaluated by the cumulative index L10, but some investigators suggest that the L10 cannot represent an adverse comment on vibration. In order to clarify the compliant, various factors involving vibration need to be analysed together by statistical methods, for instance factor analys... | ['Acceleration', 'Building Codes', 'Facility Design and Construction', 'Housing', 'Humans', 'Kinesthesis', 'Sensation', 'Transportation', 'Vibration'] | 9,583,308 | [['G01.482.107'], ['N02.278.200.100'], ['J01.086.339', 'N02.278.200'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['F02.830.816', 'G11.561.790'], ['J01.937'], ['G01.374.930']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Identification of two normal bcr gene products in the cytoplasm. | A monoclonal antibody (7C6) has been derived against a synthetic bcr peptide and used to study normal bcr gene products. The expression of a bcr phosphoprotein of 130 kd was demonstrated, in addition to the previously identified bcr phosphoprotein of 160 kd. Sequential immunoprecipitation demonstrated that both p160 an... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Cell Line', 'Chromosomes, Human, Pair 22', 'Fluorescent Antibody Technique', 'Fusion Proteins, bcr-abl', 'Humans', 'Mice', 'Molecular Sequence Data', 'Molecular Weight', 'Oligopeptides', 'Phosphorylation', 'Protein Biosynthesis', 'Protein-Tyrosine Kinases', ... | 3,078,961 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.251.210'], ['A11.284.187.520.300.505.515', 'G05.360.162.520.300.505.515'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.24... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Statewide Implementation of Virtual Perinatal Home Visiting During COVID-19. | PURPOSE: This evaluation describes efforts taken by MIECHV administrators and staff during the pandemic using data collected from 60 MIECHV staff surveys and nine statewide weekly focus groups.DESCRIPTION: The Florida Maternal, Infant and Early Childhood Home Visiting (MIECHV) Initiative funds perinatal home visiting f... | ['Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Female', 'Florida', 'House Calls', 'Humans', 'Pandemics', 'Pneumonia, Viral', 'Postnatal Care', 'Pregnancy', 'Program Development', 'Program Evaluation', 'SARS-CoV-2', 'Telemedicine'] | 32,691,359 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['Z01.107.567.875.750.350'], ['N04.452.758.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.8... | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Uncovering the cultural context for quality of family caregiving for elders. | This article is part of a symposium exploring issues in developing cross-culturally equivalent conceptualizations and measures for a study of elder family caregiving. This article describes the development of an instrument to measure quality of elder family caregiving among Anglo and Mexican American caregivers. Follow... | ['Aged', 'Caregivers', 'Cross-Cultural Comparison', 'Europe', 'Family', 'Home Nursing', 'Human Rights', 'Humans', 'Mexican Americans', 'Models, Nursing', 'Nursing Assessment', 'Quality of Health Care', 'Southwestern United States'] | 8,693,723 | [['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['Z01.542'], ['F01.829.263', 'I01.880.853.150'], ['E02.760.611.470', 'N02.421.143.524.470', 'N02.421.533.320'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Environmental fate and risk of ultraviolet- and visible-light-transformed graphene oxide: A comparative study. | Currently, there is little comparative data on the colloidal stability and the toxicity of ultraviolet (UV)- and visible-light (VL)-transformed graphene oxide (GO). In order to identify this knowledge gap, the physicochemical properties of UV/VL-transformed GO are investigated in detail. Attempts are made to correlate ... | ['Escherichia coli', 'Graphite', 'Light', 'Organic Chemicals', 'Oxides', 'Staphylococcus aureus', 'Ultraviolet Rays', 'Water', 'Water Pollutants, Chemical'] | 31,125,812 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.268.150.300', 'D01.578.300'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02'], ['D01.248.497.158.685', 'D01.650.550'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Food consumption and the risk of type 1 diabetes in children and youth: a population-based, case-control study in Prince Edward Island, Canada. | OBJECTIVE: The objective of this study was to determine if the consumption of certain foods during the year prior to diagnosis of type 1 diabetes mellitus (T1D) was associated with the risk of developing T1D in children and youth residing in Prince Edward Island, Canada.METHODS: Cases (n = 57) consisted of newly diagno... | ['Adolescent', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Diet', 'Drinking', 'Eggs', 'Feeding Behavior', 'Female', 'Humans', 'Infant', 'Male', 'Prince Edward Island', 'Risk Factors', 'Surveys and Questionnaires', 'Young Adult'] | 18,838,530 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G07.203.650.240'], ['G07.203.650.283.249', 'G10.261.330.249'], ['G07.203.300.470', 'J02.500.470'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Effect of musculoskeletal pain on sexuality of male adolescents and adults with juvenile idiopathic arthritis. | OBJECTIVE: To develop a questionnaire for the evaluation of sexuality of male patients with juvenile idiopathic arthritis (JIA).METHODS: A cohort of male patients with rheumatoid factor (RF)-negative polyarticular JIA according to the 2004 revised ILAR criteria and inactive disease was studied. The Health Assessment Qu... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Arthritis, Juvenile', 'Cohort Studies', 'Health Status', 'Humans', 'Joints', 'Male', 'Musculoskeletal System', 'Pain', 'Quality of Life', 'Severity of Illness Index', 'Sexual Behavior', 'Surveys and Questionnaires', 'Young Adult'] | 19,411,396 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Immunological evidence that insulin activates protein kinase C in BC3H-1 myocytes. | Effects of insulin on immunoreactive protein kinase C were examined in BC3H-1 myocytes. Insulin provoked rapid dose-dependent decreases in cytosolic enzyme, and transient increases and subsequent decreases in membrane-associated enzyme. Phorbol esters provoked similar changes. Our findings suggest that insulin provokes... | ['Blotting, Western', 'Cell Line', 'Cell Membrane', 'Cytosol', 'Enzyme Activation', 'Insulin', 'Muscles', 'Protein Kinase C', 'Tetradecanoylphorbol Acetate'] | 2,647,516 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['A11.284.149'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G02.111.263', 'G03.328'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A02.633', 'A10.690'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Mission Reliability-Driven Manufacturing System Health State Evaluation Method Based on Fusion of Operational Data. | The rapid development of complexity and intelligence in manufacturing systems leads to an increase in potential operational risks and therefore requires a more comprehensive system-level health diagnostics approach. Based on the massive multi-source operational data collected by smart sensors, this paper proposes a mis... | ['Algorithms', 'Data Interpretation, Statistical', 'Humans', 'Information Storage and Retrieval', 'Monitoring, Physiologic', 'Reproducibility of Results'] | 30,678,187 | [['G17.035', 'L01.224.050'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['E01.370.520'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Haemolysis in vivo by therapeutic intensities of ultrasound. | Therapeutic intensities of MHz ultrasound directed at the upper abdominal area of rats in vivo resulted in damage to the circulating red blood cells. This damage was detected as free haemoglobin in the plasma as well as microspheres and spherocytic cell fragments which are characteristically produced when blood is heat... | ['Animals', 'Burns', 'Erythrocytes', 'Hemoglobins', 'Hemolysis', 'Hot Temperature', 'In Vitro Techniques', 'Liver', 'Male', 'Radio Waves', 'Rats', 'Rats, Inbred Strains', 'Time Factors', 'Ultrasonics'] | 3,727,177 | [['B01.050'], ['C26.200'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D12.776.124.400', 'D12.776.422.316.762'], ['C23.550.403', 'G12.122.545'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['E05.481'], ['A03.620'], ['G... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparison of optic disc topographic parameters in patients with primary open angle glaucoma, normal tension glaucoma, and ocular hypertension. | BACKGROUND: Heidelberg Retina Tomograph (HRT) findings have been employed to quantitatively assess the topography of optic discs. We measured topographic parameters of optic discs in patients with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and ocular hypertension (OH) using an HRT in order to de... | ['Aged', 'Diagnosis, Computer-Assisted', 'Female', 'Glaucoma', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Ocular Hypertension', 'Optic Disk', 'Tomography'] | 12,819,980 | [['M01.060.116.100'], ['E01.158', 'L01.313.500.750.100.158'], ['C11.525.381'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['C11.525'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['E01.370.350.825']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A sensitive method for the determination of iodine containing diagnostic agents in aqueous matrices using LC-electrospray-tandem-MS detection. | Iodinated contrast media belong to the most frequently applied compounds in medicine. They exhibit a high polarity and are very persistent against metabolism by the organism and environmental degradation. A sensitive method for the determination of five iodinated contrast media in aqueous matrices is described. Solid p... | ['Chromatography, High Pressure Liquid', 'Contrast Media', 'Fresh Water', 'Mass Spectrometry', 'Medical Waste', 'Molecular Structure', 'Sensitivity and Specificity', 'Water Pollutants'] | 11,227,418 | [['E05.196.181.400.300'], ['D27.505.259.500', 'D27.720.259'], ['G16.500.275.280', 'N06.230.232'], ['E05.196.566'], ['D20.944.460', 'N06.850.460.710.460'], ['G02.111.570', 'G02.466'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vision and self-rated health: longitudinal findings from an older Australian population. | PURPOSE: To assess temporal associations between vision and self-rated health.METHODS: We examined 3654 Australian residents (82.4% response) aged 49+ years in the Blue Mountains Eye Study, during 1992 to 1994, and re-examined 2334 in 1997 to 1999. Change in vision was defined if baseline and 5-year visual acuity (VA) ... | ['Aged', 'Aging', 'Cohort Studies', 'Female', 'Health Status', 'Health Surveys', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'New South Wales', 'Self Disclosure', 'Vision Disorders', 'Vision, Ocular', 'Visual Acuity', 'Visually Impaired Persons'] | 16,036,476 | [['M01.060.116.100'], ['G07.345.124'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Primary versus secondary stereotypic movements]. | Stereotypic movements are repetitive patterns of movements whose physiopathology and relations to other neurobehavioural disorders are still only poorly understood. In this paper our aim is to distinguish between primary stereotypic movements, which are the sole manifestation of an anomaly, while the complementary exam... | ['Humans', 'Intellectual Disability', 'Rett Syndrome', 'Stereotyped Behavior', 'Stereotypic Movement Disorder'] | 15,011,149 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['C10.597.606.360.455.937', 'C16.320.322.500.937', 'C16.320.400.525.937'], ['F01.145.896'], ['F03.625.984']] | ['Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria. | Plasmodium falciparum infection can abruptly progress to severe malaria, a life-threatening complication resulting from sequestration of parasitized red blood cells (PRBC) in the microvasculature of various organs such as the brain and lungs. PRBC adhesion can induce endothelial cell (EC) activation and apoptosis, ther... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Adolescent', 'Animals', 'Antimalarials', 'Apoptosis', 'Cell Adhesion', 'Child', 'Child, Preschool', 'Endothelium, Vascular', 'Humans', 'Infant', 'Malaria, Falciparum', 'Plasmodium falciparum'] | 20,949,056 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['M01.060.057'], ['B01.050'], ['D27.505.954.122.250.100.085'], ['G04.146.954.035'], ['G04.022'], ['M01.060.406'], ['M01.060.406.448'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.610.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serum vitamin D concentration does not predict insulin action or secretion in European subjects with the metabolic syndrome. | OBJECTIVE: To investigate the relation between serum concentration of 25-hydroxyvitamin D [25(OH)D] and insulin action and secretion.RESEARCH DESIGN AND METHODS: In a cross-sectional study of 446 Pan-European subjects with the metabolic syndrome, insulin action and secretion were assessed by homeostasis model assessmen... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Vitamin D'] | 20,067,973 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['D04.210.500.812.768']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Substrate specificity of recombinant human renal renin: effect of histidine in the P2 subsite on pH dependence. | Steady-state kinetic analysis of human renin demonstrates the histidine proximal to the substrate scissile peptide bond contributes to the unique specificity and pH dependence of this aspartyl protease. Recombinant human renal renin purified from mammalian cell culture appears to be indistinguishable from renin isolate... | ['Animals', 'Binding Sites', 'Cell Line', 'Enzyme Precursors', 'Histidine', 'Humans', 'Hydrogen-Ion Concentration', 'Kidney', 'Kinetics', 'Models, Molecular', 'Protein Binding', 'Recombinant Proteins', 'Renin', 'Renin-Angiotensin System', 'Substrate Specificity', 'Transfection'] | 2,186,807 | [['B01.050'], ['G02.111.570.120'], ['A11.251.210'], ['D08.622', 'D12.776.811.243'], ['D12.125.072.329', 'D12.125.142.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['G02.111.679', 'G03.808'], ['D12.776.828'], ['D08.811.277.656.074.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surgical management of primary intrathoracic goiters. | Intrathoracic goiters account for 3.1%-5.8% of all mediastinal masses. Primary intrathoracic goiters, which receive their blood supply from mediastinal vessels and disconnect at the cervical thyroid, are even rarer. This report presents two cases of surgical resection of benign and malignant primary intrathoracic goite... | ['Aged', 'Biopsy, Fine-Needle', 'Female', 'Fluorodeoxyglucose F18', 'Goiter, Substernal', 'Humans', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Positron-Emission Tomography', 'Predictive Value of Tests', 'Radiopharmaceuticals', 'Sternotomy', 'Thoracic Neoplasms', 'Thyroidectomy', 'Tomography, X-Ray Computed', 'Treatm... | 22,419,189 | [['M01.060.116.100'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['D09.254.229.500'], ['C19.874.283.601'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors affecting the rise of treatment of resistant bacteria in skin and soft tissue infections in the United States: 1993-2012 | BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) prevalence has been steadily increasing for the past 40 years. The increase in such infections has contributed to a change in the treatment patterns of the patient. This study aimed to detail the factors determining p... | ['Adolescent', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Drug Prescriptions', 'Drug Resistance, Bacterial', 'Female', 'Health Care Surveys', 'Humans', 'Logistic Models', 'Male', 'Methicillin-Resistant Staphylococcus aureus', 'Middle Aged', 'Odds Ratio', 'Prevalence', 'Soft Tissue Infections', 'Staphylococcal Skin Infe... | 27,813,433 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['E02.319.307', 'N02.421.668.778.500'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sex Determining Region Y Box 9 Induces Chemoresistance in Pancreatic Cancer Cells by Induction of Putative Cancer Stem Cell Characteristics and Its High Expression Predicts Poor Prognosis. | OBJECTIVES: Pancreatic cancer is a highly chemoresistant tumor and underlying mechanisms are not well understood. Sex determining region Y box 9 (Sox9) is a transcription factor playing important roles on maintenance of pluripotent cells during pancreatic organogenesis. The purpose of this study is to evaluate the role... | ['Animals', 'Cell Line, Tumor', 'Doxycycline', 'Drug Resistance, Neoplasm', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice, Nude', 'Neoplastic Stem Cells', 'Pancreatic Neoplasms', 'Prognosis', 'RNA Interference', 'RNAi Therapeutics', 'SOX9 Transcription Factor', 'Xenograft Model Antitumor Assays'] | 28,984,791 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['G07.690.773.984.395'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['A11.872.650'], ['C04.588.274.761', 'C04.588.322.475', 'C06.3... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physiological and behavioral effects of chronic intracerebroventricular infusion of corticotropin-releasing factor in the rat. | The present study was conducted to investigate the long-term effects of chronic elevation of centrally circulating levels of corticotropin-releasing factor (CRF) on behavior and physiology. For this purpose ovine CRF was infused continuously for a period of 10 days into the lateral ventricle of rats with the aid of osm... | ['Animals', 'Arousal', 'Body Temperature Regulation', 'Body Weight', 'Brain', 'Circadian Rhythm', 'Corticotropin-Releasing Hormone', 'Infusion Pumps', 'Injections, Intraventricular', 'Male', 'Motor Activity', 'Rats', 'Rats, Wistar'] | 9,279,936 | [['B01.050'], ['F02.830.104', 'G11.561.035'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['G07.180.562.190'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
7th International Immunoglobulin Conference: Transplantation. | In transplantation, harnessing the immune system is essential for allograft survival and function. This session explores different aspects of the immune system during transplantation, including the effect of donor-specific anti-human leucocyte antigen (HLA) antibodies (DSAs), antibody-mediated rejection (AMR), B cell m... | ['B-Lymphocytes', 'Desensitization, Immunologic', 'Graft Rejection', 'Graft Survival', 'HLA Antigens', 'Humans', 'Immunoglobulins, Intravenous', 'Transplantation'] | 25,546,758 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E02.095.465.425.450.310', 'E05.478.610.310'], ['G12.875.545.328'], ['G12.875.545.340'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.1... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary total antioxidant capacity and risk of cancer: a systematic review and meta-analysis on observational studies. | BACKGROUND: Recent studies have shown that dietary total antioxidant capacity (D-TAC) may affect risk of cancer; however, findings are conflicting. Hence, we aimed to summarize the current evidence on the association between D-TAC and risk of cancer.METHODS: We searched the online databases of PubMed, ISI Web of Scienc... | ['Antioxidants', 'Diet', 'Female', 'Humans', 'Neoplasms', 'Risk'] | 31,092,388 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Studies on Niuxi with the method of FT-IR spectroscopy and analyze technology auxiliary]. | OBJECTIVE: To study the genuine of 32 samples of Niuxi from 14 provinces, and compare some samples stored for different time to check the change in the coures of store.METHOD: IR spectroscopy and Analyze Technology Auxiliary softeare.RESULT: The coefficient correlations had certain difference among these Niuxi from dif... | ['Achyranthes', 'Drug Contamination', 'Drug Storage', 'Drugs, Chinese Herbal', 'Image Processing, Computer-Assisted', 'Mathematics', 'Plant Roots', 'Plants, Medicinal', 'Quality Control', 'Spectroscopy, Fourier Transform Infrared', 'Time Factors'] | 16,107,025 | [['B01.650.940.800.575.912.250.198.500.100.100'], ['N06.850.360'], ['E05.916.350'], ['D20.215.784.500.350', 'D26.335'], ['L01.224.308'], ['H01.548'], ['A18.400'], ['B01.650.560'], ['J01.897.608'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G01.910.857']] | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro. | Epigallocatechin gallate (EGCG), the major catechin contained in tea leaves, is known to possess the synergistic anti-staphylococcal activity in combination with various â-lactam antibiotics and tetracycline. In the present study, we explored the in vitro combinatory effect of EGCG in combination with oxytetracycline a... | ['Anti-Bacterial Agents', 'Catechin', 'Drug Resistance, Multiple, Bacterial', 'Drug Synergism', 'Erythromycin', 'Methicillin Resistance', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Oxytetracycline', 'Plant Leaves', 'Tea', 'Tetracycline', 'Tetracycline Resistance'] | 23,485,046 | [['D27.505.954.122.085'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['G07.690.773.968.477'], ['D02.540.576.500.992'], ['G06.099.225.500.600.525', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Beating and arrested intramyocardial injections are associated with significant mechanical loss: implications for cardiac cell transplantation. | BACKGROUND: Cellular cardiomyoplasty is emerging as a potentially novel therapeutic option for heart failure and typically involves direct intramyocardial injection of donor cells into a beating heart. Yet, limited rates of cell engraftment remain an obstacle to be overcome before cell therapy is fully recognized. Mech... | ['Animals', 'Cardiomyoplasty', 'Cardiopulmonary Bypass', 'Cell Transplantation', 'Female', 'Fluorescence', 'Heart', 'Heart Arrest, Induced', 'Heart Ventricles', 'Injections', 'Male', 'Microspheres', 'Models, Animal', 'Myocardial Contraction', 'Sus scrofa'] | 17,719,065 | [['B01.050'], ['E04.100.376.125', 'E04.928.220.220'], ['E04.292.413'], ['E02.095.147.500', 'E04.936.225'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['A07.541'], ['E04.100.376.374', 'E04.928.220.360'], ['A07.541.560'], ['E02.319.267.530'], ['E07.565'], ['E05.598'], ['G09.330.580', 'G11.427.494.570'], ['B0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heat stress-induced protection of endothelial function against ischaemic injury is abolished by ATP-sensitive potassium channel blockade in the isolated rat heart. | The protection conferred by heat stress (HS) against myocardial ischaemia-reperfusion injury, in terms of mechanical function preservation and infarct size reduction, is well documented and mechanisms underlying these effects have been extensively explored. However, the effect of HS on coronary circulation is less know... | ['ATP-Binding Cassette Transporters', 'Animals', 'Blood Pressure', 'Endothelium, Vascular', 'Glyburide', 'Heart Rate', 'Heat Stress Disorders', 'Hypoglycemic Agents', 'Ischemic Preconditioning', 'KATP Channels', 'Male', 'Myocardial Reperfusion Injury', 'Potassium Channel Blockers', 'Potassium Channels', 'Potassium Chan... | 10,807,672 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['E01.370.600.875.500', 'G09.330.380.500'], ['C26.522'], ['D27.505.696.422'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The EHEC O104:H4 outbreak in Germany 2011 - lessons learned?!]. | The EHEC O104:H4 outbreak 2011 in Germany provided numerous insights into the recognition and control of such epidemic situations. Food-borne outbreaks and their related dynamics may lead to a critical burden of disease and an eventual capacity overload of the medical care system. Possible difficulties in the microbiol... | ['Disease Outbreaks', 'Escherichia coli Infections', 'Escherichia coli O157', 'Germany', 'Health Communication', 'Hemolytic-Uremic Syndrome', 'Humans', 'Incidence', 'Population Surveillance', 'Risk Assessment'] | 23,576,144 | [['N06.850.290'], ['C01.150.252.400.310.330'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150.180.100.800.250.500'], ['Z01.542.315'], ['L01.143.350', 'N02.208'], ['C12.777.419.936.463', 'C13.351.968.419.936.463', 'C15.378.071.141.610', 'C15.378.140.855.925.500'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Noninvasive genotyping and monitoring of anaplastic lymphoma kinase (ALK) rearranged non-small cell lung cancer by capture-based next-generation sequencing. | Noninvasive genotyping of driver genes and monitoring of tumor dynamics help make better personalized therapeutic decisions. However, neither PCR-based assays nor amplicon-based targeted sequencing can detect fusion genes like anaplastic lymphoma kinase (ALK) rearrangements in blood samples. To investigate the feasibil... | ['Adult', 'Aged', 'Anaplastic Lymphoma Kinase', 'Carcinoma, Non-Small-Cell Lung', 'Cell-Free Nucleic Acids', 'Circulating Tumor DNA', 'Female', 'Gene Rearrangement', 'Genotype', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Receptor Protein-Tyrosine Kinases', 'Sensitivity ... | 27,564,104 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.696.620.682.725.400.002', 'D12.776.543.750.630.002'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D13.444.154'], ['D13.444.154.500', 'D13.444.308.425.500'], ['G05.344'], ['G05.380'], ['E05.393.760.319'], ['B01.050.150.900.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[In vitro antibacterial activity of neomycin, bacitracin and a combination of both]. | Bacitracin and neomycin have been used for a long time for local intestinal antisepsis or decontamination, due to their scarce or nonexistent intestinal absorption. The aim of the present study was to determine the activity of bacitracin and neomycin against recent clinical isolates of aerobic and anaerobic microorgani... | ['Bacitracin', 'Bacteria, Aerobic', 'Bacteria, Anaerobic', 'Drug Resistance, Microbial', 'Drug Synergism', 'Drug Therapy, Combination', 'Microbial Sensitivity Tests', 'Neomycin'] | 2,488,912 | [['D04.345.566.075', 'D12.644.641.075'], ['B03.120'], ['B03.130'], ['G06.225', 'G07.690.773.984.269'], ['G07.690.773.968.477'], ['E02.319.310'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D09.408.051.623']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES). | Fractionated excretory/secretory products (ES) of adult Haemonchus contortus were evaluated as protective antigens. The proteins were successively eluted from a Thiol Sepharose column using 25 mM cysteine followed by 25 mM Dl-dithiothreitol (DTT). Sheep were vaccinated three times and challenged with 5000 third stage i... | ['Abomasum', 'Animals', 'Antibodies, Helminth', 'Antigens, Helminth', 'Chromatography, Agarose', 'Cysteine Endopeptidases', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Feces', 'Haemonchiasis', 'Haemonchus', 'Immunization', 'Immunoglobulin G', 'Lymphocyte Count', 'Mucus', 'Parasite Egg C... | 14,741,153 | [['A13.869.106'], ['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['D23.050.223'], ['E05.196.181.400.250.200'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sinking skin flap syndrome and paradoxical herniation secondary to lumbar drainage. | OBJECTIVE: Decompressive craniectomy (DC) has been regaining popularity in the field of neurosurgery because it can alleviate intracranial hypertension and brain swelling. Lumbar drainage (LD) is affective in managing numerous neurosurgical circumstances such as aneurysmal subarachnoid hemorrhage, refractory intracrani... | ['Adult', 'Aged', 'Brain', 'Cerebrospinal Fluid', 'Decompressive Craniectomy', 'Drainage', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Postoperative Complications', 'Risk Factors', 'Scalp', 'Syndrome', 'Treatment Outcome', 'Trephining'] | 25,817,571 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['A12.207.270.210'], ['E04.188.200', 'E04.525.190.200'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Blood pressure and hypertension are associated with 7 loci in the Japanese population. | BACKGROUND: Two consortium-based genome-wide association studies have recently identified robust and significant associations of common variants with systolic and diastolic blood pressures in populations of European descent, warranting further investigation in populations of non-European descent.METHODS AND RESULTS: We... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'Blood Pressure', 'Cross-Sectional Studies', 'DNA-Binding Proteins', 'Female', 'Fibroblast Growth Factor 5', 'Genetic Loci', 'Humans', 'Hypertension', 'Integrins', 'Japan', 'Male', 'Middle Aged', 'Plasma Membrane Calcium-Transporti... | 20,479,155 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D12.776.260'], ['D12.644.276.624.150', 'D12.776.467.624.150', 'D23.529.624.150'], ['G05.360.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Uncompacted myelin lamellae in dysglobulinemic neuropathy. | Uncompacted lamellae, located preferentially in inner layers of myelin sheath, were observed in biopsied sural nerves of 3 cases of dysglobulinemic neuropathy, in which the main pathological findings of myelinated fibers were those of segmental demyelination and remyelination, and axonal degeneration with concurrent ma... | ['Adult', 'Dysgammaglobulinemia', 'Female', 'Humans', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Myelin Sheath', 'Peripheral Nervous System Diseases'] | 6,265,601 | [['M01.060.116'], ['C15.378.147.333', 'C20.673.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149.165.600', 'A11.650.600.500', 'A11.650.800.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differentially expressed and activated proteins associated with non small cell lung cancer tissues. | BACKGROUND: Lung cancer is a leading cause of mortality. The most common cancer subtype, non small cell lung cancer (NSCLC), accounts for 85-90% all cases and is mainly caused by environmental and genetic factors. Mechanisms involved in lung carcinogenesis include deregulation of several kinases and molecular pathways ... | ['Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'MAP Kinase Signaling System', 'NF-kappa B', 'Neoplasm Proteins'] | 26,104,294 | [['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D05.500.672', 'D12.776.260.600', 'D12.776... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with treatment-resistant depression. | The tumor necrosis factor (TNF) antagonist infliximab was recently found to reduce depressive symptoms in patients with increased baseline inflammation as reflected by a plasma C-reactive protein concentration >5 mg/L. To further explore predictors and targets of response to infliximab, differential gene expression was... | ['Adult', 'Antibodies, Monoclonal', 'Antidepressive Agents', 'Carbohydrate Metabolism', 'Depressive Disorder, Treatment-Resistant', 'Double-Blind Method', 'Female', 'Gene Expression Profiling', 'Glucose', 'Humans', 'Infliximab', 'Lipid Metabolism', 'Male', 'Middle Aged', 'Treatment Outcome', 'Tumor Necrosis Factor-alph... | 23,624,296 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.427.700.122'], ['G02.111.158', 'G03.191'], ['F03.600.300.388'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.393.332'], ['D09.947.875.359.448'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Down-regulating annexin gene GhAnn2 inhibits cotton fiber elongation and decreases Ca2+ influx at the cell apex. | Cotton fiber is a single cell that differentiates from the ovule epidermis and undergoes synchronous elongation with high secretion and growth rate. Apart from economic importance, cotton fiber provides an excellent single-celled model for studying mechanisms of cell-growth. Annexins are Ca(2+)- and phospholipid-bindin... | ['Annexins', 'Calcium', 'Calcium Signaling', 'Cell Enlargement', 'Cotton Fiber', 'Down-Regulation', 'Expressed Sequence Tags', 'Gossypium', 'Phylogeny', 'Plant Proteins', 'Polymorphism, Single Nucleotide', 'RNA Interference', 'Sequence Analysis'] | 24,890,373 | [['D12.776.157.125.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['G04.161.500', 'G07.345.249.410.500'], ['J01.637.836.299'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.360.340.024.340.137.275'], ['B01.650.940.800.575.912.250.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Hemorrhoidectomy with stapler vs. traditional hemorrhoidectomy: comparative outcome of 2 groups of patients]. | Authors compare the results of two groups of patients, with III and IV degree haemorrhoids. The first group (48 patients) were treated with traditional surgery, open or closed. The second group (42 patients) treated with stapling haemorrhoidectomy. The groups were compared in order to determine if a true advantage exis... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Hemorrhoids', 'Humans', 'Ligation', 'Male', 'Middle Aged', 'Pain, Postoperative', 'Postoperative Complications', 'Rectal Prolapse', 'Surgical Staplers', 'Time Factors'] | 12,197,292 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C06.405.469.860.401', 'C14.907.449'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.426'], ['M01.060.116.630'], ['C23.550.767.700', 'C23.888.592.612.832'], ['C23.550.767'], ['C06.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dairy soil bacterial responses to nitrogen application in simulated Italian ryegrass and white clover pasture. | Through clearing and use of fertilizer and legumes, areas of southwestern Australia's unique coastal sand plains can support relatively low-cost dairies. However, the ancient, highly weathered nature of the soils in this region makes the dairies susceptible to a range of threats, including nutrient leaching and erosion... | ['Animals', 'Australia', 'Bacteria', 'Cattle', 'Female', 'Fertilizers', 'Italy', 'Lolium', 'Milk', 'Nitrates', 'Nitrogen', 'Soil Microbiology', 'Trifolium'] | 31,351,712 | [['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['B03'], ['B01.050.150.900.649.313.500.380.271'], ['D27.720.031.400'], ['Z01.542.489'], ['B01.650.940.800.575.912.250.822.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['D01.248.497.158.606', 'D01.625.525.... | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Leptin levels in different forms of Chagas' disease. | Leptin is produced primarily by adipocytes. Although originally associated with the central regulation of satiety and energy metabolism, increasing evidence indicates that leptin may be an important mediator in cardiovascular pathophysiology. The aim of the present study was to investigate plasma leptin levels in patie... | ['Adult', 'Biomarkers', 'Body Mass Index', 'Case-Control Studies', 'Chagas Cardiomyopathy', 'Chagas Disease', 'Echocardiography', 'Electrocardiography', 'Female', 'Fluoroimmunoassay', 'Heart Failure', 'Humans', 'Leptin', 'Male', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Ventricular Dysfunction,... | 17,713,658 | [['M01.060.116'], ['D23.101'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.610.752.300.900.200.190', 'C01.920.625.190', 'C14.280.238.190'], ['C01.610.752.300.900.200', 'C01.920.625'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transcriptomic analysis of American ginseng seeds during the dormancy release process by RNA-Seq. | American ginseng (Panax quinquefolius L.) is an important herb that is cultivated in China, North American, and South Korea. It is propagated from seed, but the seed has deep dormancy characteristics described as morphophysiological dormancy. Two-stage temperature stratification, a warm (15-20°C) and cold (2°C) stratif... | ['Base Sequence', 'Computational Biology', 'Gene Expression Profiling', 'Genes, Plant', 'Molecular Sequence Annotation', 'Molecular Sequence Data', 'Panax', 'Plant Dormancy', 'Seeds', 'Sequence Analysis, RNA', 'Sequence Homology', 'Transcriptome'] | 25,790,114 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.158.273.180', 'L01.313.124'], ['E05.393.332'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['E05.393.760.479', 'L01.453.245.667.580'], ['L01.453.245.667'], ['B01.650.940.800.575.912.250.087.500'], ['G07.345.625.875', 'G15.357.500'], ['A18.024.500... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
The effects of a transitional discharge model for psychiatric patients. | This pilot randomized control trial was motivated by the discovery that many individuals with mental health problems are re-hospitalized within a year, with many being unable to fully adjust to community living. A solution was proposed in the form of an intervention called transitional discharge. The transitional disch... | ['Acute Disease', 'Aftercare', 'Community Mental Health Services', 'Continuity of Patient Care', 'Health Services Research', 'Hospitals, Psychiatric', 'Humans', 'Interinstitutional Relations', 'Length of Stay', 'Mental Disorders', 'Models, Nursing', 'Models, Organizational', "Nurse's Role", 'Nursing Evaluation Research... | 14,723,643 | [['C23.550.291.125'], ['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Isolation and identification of Peptococcus saccharolyticus from human skin. | Peptococcus saccharolyticus was a numerically important organism on the forehead and the antecubital fossa of the arm of ca. 20% of the subjects studied. It was best detected by prolonged (4- to 7-day) anaerobic incubation on a suitably enriched medium but also appeared in smaller numbers in aerobic primary cultures af... | ['Aerobiosis', 'Anaerobiosis', 'Arm', 'Forehead', 'Humans', 'Peptococcus', 'Skin'] | 649,761 | [['G02.111.017', 'G03.049'], ['G02.111.062', 'G03.078'], ['A01.378.800.075'], ['A01.456.505.580'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.625.782.593', 'B03.510.400.562.593'], ['A17.815']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells. | Tyrosinase-related protein-2 (TRP-2) is a DOPAchrome tautomerase catalyzing a distal step in the melanin synthesis pathway. Similar to the other two melanogenic enzymes belonging to the TRP gene family, tyrosinase and TRP-1, TRP-2 is expressed in melanocytes and melanoma cells. Despite the increasing evidence of its ef... | ['Animals', 'Biological Transport, Active', 'Calnexin', 'Calreticulin', 'Cysteine Endopeptidases', 'Endoplasmic Reticulum', 'Golgi Apparatus', 'Intramolecular Oxidoreductases', 'Melanoma, Experimental', 'Melanosomes', 'Mice', 'Multienzyme Complexes', 'Polysaccharides', 'Proteasome Endopeptidase Complex', 'Protein Confo... | 12,719,423 | [['B01.050'], ['G03.143.310'], ['D12.644.360.372.311', 'D12.776.157.125.412.311', 'D12.776.476.387.311', 'D12.776.503.295', 'D12.776.543.162'], ['D12.644.360.372.374', 'D12.776.157.125.412.374', 'D12.776.476.387.374', 'D12.776.503.303'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['A11.284.430.214.190.875.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A testing-coverage software reliability model considering fault removal efficiency and error generation. | In this paper, we propose a software reliability model that considers not only error generation but also fault removal efficiency combined with testing coverage information based on a nonhomogeneous Poisson process (NHPP). During the past four decades, many software reliability growth models (SRGMs) based on NHPP have ... | ['Databases as Topic', 'Least-Squares Analysis', 'Likelihood Functions', 'Poisson Distribution', 'Reproducibility of Results', 'Software'] | 28,750,091 | [['L01.313.500.750.300.188', 'L01.470.750'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['E05.318.740.994.750... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Predictors of contact tracing completion and outcomes in tuberculosis: a 21-year retrospective cohort study. | SETTING: Birmingham, UK, 1990-2010.OBJECTIVE: To identify predictors in contacts for completion of screening and of a positive screening outcome, i.e., a diagnosis of latent tuberculous infection (LTBI) or active tuberculosis (TB).DESIGN: A retrospective cohort study of TB notifications for a European city.RESULTS: A t... | ['Adolescent', 'Adult', 'Aged', 'Antitubercular Agents', 'Bacteriological Techniques', 'Child', 'Child, Preschool', 'Contact Tracing', 'England', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Interferon-gamma Release Tests', 'Latent Tuberculosis', 'Male', 'Middle Aged', 'Mycobacterium tuberculosis', 'Patient Accept... | 24,903,932 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085.255'], ['E01.370.225.875.150', 'E05.200.875.150'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.270', 'N06.850.520.270', 'N06.850.780.200.225'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Child care practices of mothers: implications for intervention in acute respiratory infections. | An epidemiological study of acute respiratory infection (ARI) in an urban community showed poor utilization of available health services. This prompted us to undertake this study to identify determinants of child care practices of mothers through a focus group discussion and survey of the knowledge, attitudes and pract... | ['Acute Disease', 'Attitude to Health', 'Child', 'Child Health Services', 'Child, Preschool', 'Cross-Sectional Studies', 'Health Services, Indigenous', 'Home Nursing', 'Humans', 'Infant', 'Infant, Newborn', 'Philippines', 'Respiratory Tract Infections', 'Rural Health', 'Self Medication', 'Socioeconomic Factors'] | 2,473,706 | [['C23.550.291.125'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['N02.421.143.130'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N02.421.330'], ['E02.760.611.470', 'N02.421.143.524.470', 'N02.421.533.320'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mapping by synthetic peptides of the binding sites for acetylcholine receptor on alpha-bungarotoxin. | A set of seven peptides constituting the various loops and most of the surface areas of alpha-bungarotoxin (BgTX) was synthesized. In appropriate peptides, the cyclical (by a disulfide bond) monomers were prepared. In all cases, the peptides were purified and characterized. The ability of these peptides to bind Torpedo... | ['Amino Acid Sequence', 'Amino Acids', 'Bungarotoxins', 'Molecular Sequence Data', 'Peptide Mapping', 'Peptides', 'Receptors, Cholinergic'] | 3,255,383 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['D20.888.850.325.139', 'D23.946.833.850.325.139'], ['L01.453.245.667'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['D12.644'], ['D12.776.543.750.720.360']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Disorder of blood-aqueous barrier following Ahmed Glaucoma Valve implantation. | BACKGROUND: Ahmed Glaucoma Valve implantation (AGVI) is used to treat refractory glaucoma. Breakdown of the blood-aqueous barrier (BAB) has been noted after some surgical techniques. The current study was designed to assess BAB disruption after AGVI.METHODS: Anterior chamber protein content was measured by the laser fl... | ['Adult', 'Aqueous Humor', 'Blood-Aqueous Barrier', 'Female', 'Glaucoma Drainage Implants', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies'] | 23,506,590 | [['M01.060.116'], ['A09.371.060.067.070', 'A12.207.270.040'], ['A07.030', 'A09.371.894.030'], ['E07.695.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Correlation of IDH1 and B7H3 expression with prognosis of CRC patients. | BACKGROUND: B7H3 is an immuno-stimulatory glycoprotein that is overexpressed in cancer. However, its functional contributions to cancer development and progression are not well understood. In several reports, it was demonstrated that B7H3 reprograms lipid metabolism and regulates glucose metabolism. Isocitrate dehydrog... | ['Adult', 'Aged', 'B7 Antigens', 'Biomarkers, Tumor', 'Blotting, Western', 'Colorectal Neoplasms', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'Isocitrate Dehydrogenase', 'Male', 'Middle Aged', 'Prognosis', 'RNA, Neoplasm', 'Real-Time Polymerase Chain Reaction', 'Retrospective ... | 29,871,819 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.467.150', 'D12.776.543.095', 'D23.050.301.285', 'D23.529.168'], ['D23.101.140'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.15... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation of the intermediate filament protein vimentin by chromatofocusing. | A novel, simple and relatively rapid method is described for the isolation of the intermediate-sized filament protein vimentin from eye lens tissue. Chromatofocusing is applied as the sole purification step. The apparent isoelectric point of the protein in 6 M urea and at 22 degrees C is 4.9. Electrophoretic mobility o... | ['Amino Acids', 'Animals', 'Cattle', 'Electrophoresis, Polyacrylamide Gel', 'Hydrogen-Ion Concentration', 'Isoelectric Focusing', 'Lens, Crystalline', 'Methods', 'Vimentin'] | 3,967,763 | [['D12.125'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.300'], ['E05.196.401.663', 'E05.301.300.663'], ['A09.371.060.500'], ['E05.581'], ['D05.750.078.593.900', 'D12.776.220.475.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hey, look over there: Distraction effects on rapid sequence recall. | In the course of everyday life, the brain must store and recall a huge variety of representations of stimuli which are presented in an ordered or sequential way. The processes by which the ordering of these various things is stored and recalled are moderately well understood. We use here a computational model of a cort... | ['Arousal', 'Attention', 'Cerebral Cortex', 'Humans', 'Mental Recall', 'Models, Neurological', 'Neuronal Plasticity'] | 32,275,703 | [['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['E05.599.395.642'], ['G11.561.638']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the effects of viprostol in isolated small blood vessels and thoracic aorta of the rat. | 1. The effects of viprostol, prostaglandin E2 (PGE2) and nitroglycerin were studied in basilar artery, small mesenteric artery and the vein parallel to it as well as thoracic aorta of the rat. 2. In KCl-contracted basilar artery, viprostol produced a concentration-related biphasic response, contraction at concentration... | ['Animals', 'Antihypertensive Agents', 'Aorta, Thoracic', 'Basilar Artery', 'Blood Vessels', 'Dinoprostone', 'Dose-Response Relationship, Drug', 'In Vitro Techniques', 'Mesenteric Arteries', 'Mesenteric Veins', 'Muscle Contraction', 'Nitroglycerin', 'Potassium Chloride', 'Prostaglandins E', 'Prostaglandins E, Synthetic... | 3,130,918 | [['B01.050'], ['D27.505.954.411.162'], ['A07.015.114.056.372'], ['A07.015.114.106'], ['A07.015'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.481'], ['A07.015.114.565'], ['A07.015.908.670.385'], ['G11.427.494'], ['D02.640.636'], ['D01.210.450.150.750', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ketorolac for pain management after abdominal surgical procedures in infants. | BACKGROUND: While the use of intravenous ketorolac in infants less than 6 months old has not been previously reported, ketorolac may reduce opioid use and prevent opioid-associated side effects that are frequent in this age group. We reviewed our experience with ketorolac in infants to develop recommendations for using... | ['Abdomen', 'Analgesics, Opioid', 'Anti-Inflammatory Agents, Non-Steroidal', 'Drug Therapy, Combination', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Infusions, Intravenous', 'Ketorolac', 'Male', 'Morphine', 'Pain Measurement', 'Pain, Postoperative', 'Retrospective Studies'] | 11,902,701 | [['A01.923.047'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A robot-guided minimally invasive approach for cochlear implant surgery: preliminary results of a temporal bone study. | PURPOSE: The aim of this study was to create an access canal to the inner ear, by drilling, and perform the cochleostomy for cochlear implant surgery using robot guidance.METHODS: A robot, a surgical drill and an Image-Guided Surgery (IGS) system were combined in a closed-loop setup. Ten temporal bones were scanned at ... | ['Cadaver', 'Cochlea', 'Cochlear Implantation', 'Humans', 'Ostomy', 'Reproducibility of Results', 'Robotics', 'Surgery, Computer-Assisted', 'Temporal Bone', 'Tomography, X-Ray Computed'] | 20,033,531 | [['C23.550.260.224'], ['A09.246.300.246'], ['E04.580.450.220', 'E04.650.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.579'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['E04.749'], ['A02.835.232.781.885... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
A genetic screen for novel behavioral mutations in mice. | A genetic screen using mice was performed to identify dominant loci affecting behavior. Mice were mutagenized with ENU, then bred to examine their G1 offspring for behavioral abnormalities. Potentially mutant G1 pups were screened through a variety of behavioral assays, including tests of learning and memory, sensorimo... | ['Alkylating Agents', 'Animals', 'Behavior, Animal', 'Conditioning, Psychological', 'Ethylnitrosourea', 'Exploratory Behavior', 'Fear', 'Female', 'Genetic Testing', 'Locomotion', 'Male', 'Memory', 'Mice', 'Mice, Inbred C57BL', 'Mice, Neurologic Mutants', 'Motor Activity', 'Mutagenesis', 'Pain Threshold', 'Reflex, Start... | 10,889,547 | [['D27.505.519.124', 'D27.888.569.035'], ['B01.050'], ['F01.145.113'], ['F02.463.425.179'], ['D02.065.950.594.310', 'D02.654.692.300'], ['F01.145.387', 'F01.658.370'], ['F01.470.361'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['G07.568.500', 'G11.427.410.568'], ['F02.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Establishment of a cerebral schistosomiasis experimental model in rabbits. | OBJECTIVE: The present study aimed to establish a cerebral schistosomiasis model in rabbits, to provide a valuable tool for morphological analysis, clinical manifestation observation, as well as investigations into immunological reactions and pathogenesis of focal inflammatory reaction in neuroschistosomiasis (NS).METH... | ['Animals', 'Cerebral Cortex', 'Disease Models, Animal', 'Eggs', 'Female', 'Male', 'Neuroschistosomiasis', 'Rabbits', 'Schistosoma japonicum', 'Time Factors'] | 21,441,970 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.203.300.470', 'J02.500.470'], ['C01.207.205.250.600', 'C01.610.105.250.600', 'C01.610.335.865.859.213', 'C01.920.922.213', 'C10.228.228.205.250.600'], ['B01.050.150.900.649.313.968.700'], ['B01.050.500.500.736.715.770.68... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Lattice light sheet imaging of membrane nanotubes between human breast cancer cells in culture and in brain metastases. | Membrane nanotubes are cytosolic protrusions with diameters <1 µm that extend between cells separated by tens of µm. They mediate several forms of intercellular communication and are upregulated in diverse diseases. Difficulties in visualizing and studying nanotubes within intact tissues have, however, prompted skeptic... | ['Animals', 'Brain', 'Brain Neoplasms', 'Breast Neoplasms', 'Cell Culture Techniques', 'Cell Surface Extensions', 'Disease Models, Animal', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Humans', 'Mice', 'Neoplasm Metastasis', 'Staining and Labeling', 'Tumor Cells, Cultured'] | 28,887,508 | [['B01.050'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.284.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.360.340.024.340.435'], ['D12.776.532.265']... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular cytogenetic identification of a novel wheat-Agropyron elongatum chromosome translocation line with powdery mildew resistance. | Agropyron elongatum (Host.) Neviski (synonym, Thinopyrum ponticum Podp., 2n = 70) has been used extensively as a valuable source for wheat breeding. Numerous chromosome fragments containing valuable genes have been successfully translocated into wheat from A. elongatum. However, reports on the transfer of powdery milde... | ['Agropyron', 'Ascomycota', 'Chromosomes, Plant', 'Cytogenetic Analysis', 'Disease Resistance', 'Expressed Sequence Tags', 'Genetic Markers', 'In Situ Hybridization, Fluorescence', 'Microsatellite Repeats', 'Phenotype', 'Plant Diseases', 'Translocation, Genetic'] | 28,886,152 | [['B01.650.940.800.575.912.250.822.033'], ['B01.300.107'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['G05.360.340.024.340.137.275'], ['D23.101.387', 'G05.695.450'... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does physical activity in adolescence have site-specific and sex-specific benefits on young adult bone size, content, and estimated strength? | The long-term benefits of habitual physical activity during adolescence on adult bone structure and strength are poorly understood. We investigated whether physically active adolescents had greater bone size, density, content, and estimated bone strength in young adulthood when compared to their peers who were inactive... | ['Adolescent', 'Adult', 'Age Factors', 'Bone Density', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Motor Activity', 'Radius', 'Sex Factors', 'Tibia', 'Tomography, X-Ray Computed', 'Young Adult'] | 23,907,819 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['G11.427.100'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['A02.835.232.087.090.700'], ['N05.... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Parental values and ethnic identity in indigenous Sami families: a qualitative study. | The qualitative study reported in this article is part of a larger multimethod investigation of child-rearing practices and child-behavior problems in indigenous Sami and majority Norwegian populations in the Sami core area in Northern Norway. In the primary quantitative study we found significant ethnic differences be... | ['Adult', 'Child Rearing', 'Child, Preschool', 'Cultural Characteristics', 'Ethnic Groups', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Norway', 'Social Values'] | 12,698,605 | [['M01.060.116'], ['F01.318'], ['M01.060.406.448'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['M01.686.754', 'N01.224.317'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.816.374'], ['F01.829.873']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Auranofin: experience to date. | Auranofin, an oral gold-containing medication for the treatment of rheumatoid arthritis, has unique chemical, pharmacologic, and kinetic characteristics. Clinical improvement is achieved with lower blood gold levels than with parenteral gold compounds. More than 3,000 patients with rheumatoid arthritis in 27 countries ... | ['Animals', 'Anti-Inflammatory Agents', 'Arthritis, Rheumatoid', 'Auranofin', 'Aurothioglucose', 'Chemical Phenomena', 'Chemistry', 'Clinical Trials as Topic', 'Dose-Response Relationship, Drug', 'Gold', 'Humans', 'Rats', 'Tissue Distribution'] | 6,419,601 | [['B01.050'], ['D27.505.954.158'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D02.691.675.249.150'], ['D02.691.675.249'], ['G02'], ['H01.181'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.268.556.322', 'D01.268... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis. | Plasma concentrations of the hormone gastrin are elevated by Helicobacter pylori infection and by gastric atrophy. It has previously been proposed that gastrin acts as a cofactor during gastric carcinogenesis and hypergastrinemic transgenic INS-GAS mice are prone to developing gastric adenocarcinoma, particularly follo... | ['Animals', 'Anti-Ulcer Agents', 'Apoptosis', 'Benzodiazepines', 'Cells, Cultured', 'Disease Susceptibility', 'Gamma Rays', 'Gastric Mucosa', 'Gastrins', 'Helicobacter pylori', 'Humans', 'Mice', 'Mice, Transgenic', 'Omeprazole', 'Receptor, Cholecystokinin B', 'Stomach Neoplasms'] | 17,900,712 | [['B01.050'], ['D27.505.954.483.203'], ['G04.146.954.035'], ['D03.633.100.079.080'], ['A11.251'], ['C23.550.291.687', 'G07.100.250'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
How to discriminate between computer-aided and computer-hindered decisions: a case study in mammography. | BACKGROUND: Computer aids can affect decisions in complex ways, potentially even making them worse; common assessment methods may miss these effects. We developed a method for estimating the quality of decisions, as well as how computer aids affect it, and applied it to computer-aided detection (CAD) of cancer, reanaly... | ['Breast Neoplasms', 'Diagnosis, Computer-Assisted', 'Female', 'Humans', 'Logistic Models', 'Mammography', 'Mass Screening', 'Probability', 'Sensitivity and Specificity'] | 23,300,205 | [['C04.588.180', 'C17.800.090.500'], ['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of Tetrahymena ciliary surface proteins labeled with sulfosuccinimidyl 6-(biotinamido) hexanoate and Concanavalin A and fractionated with Triton X-114. | Tetrahymena thermophila cells were labeled with sulfosuccinimidyl 6-(biotinamido) hexanoate, a sensitive nonradioactive probe for cell surface proteins, and Western blots of axonemes and ciliary membrane vesicles were compared to cilia fractionated with Triton X-114 (TX-114) in order to study the orientation of ciliary... | ['Animals', 'Biotin', 'Cell Fractionation', 'Cell Membrane', 'Cilia', 'Concanavalin A', 'Electrophoresis, Gel, Two-Dimensional', 'Membrane Proteins', 'Microtubules', 'Octoxynol', 'Polyethylene Glycols', 'Protozoan Proteins', 'Succinimides', 'Tetrahymena thermophila'] | 1,640,384 | [['B01.050'], ['D03.383.129.308.080', 'D08.211.096'], ['E05.242.251'], ['A11.284.149'], ['A11.284.180.165'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['E05.196.401.250', 'E05.301.300.230'], ['D12.776.543'], ['A11.284.430.214.190.750.602'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.63... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Primitive neuroectodermal tumor of the testis. Report of a case. | A 30-year-old man died of a testicular tumor with widespread metastases. Both the right testis and the adjoining epididymis were replaced by a mass that consisted mainly of small cells, but differentiated focally into medullary tubules, ependymal rosettes, and glia in which glial fibrillary acidic protein was demonstra... | ['Adult', 'Dysgerminoma', 'Epididymis', 'Humans', 'Male', 'Neoplasm Metastasis', 'Neoplasms, Germ Cell and Embryonal', 'Testicular Neoplasms'] | 6,314,925 | [['M01.060.116'], ['C04.557.465.330.300'], ['A05.360.444.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04.557.465'], ['C04.588.322.762', 'C04.588.945.440.915', 'C12.294.260.937', 'C12.758.409.937', 'C19.344.762', 'C19.391.829.782']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Meta-aligner: long-read alignment based on genome statistics. | BACKGROUND: Current development of sequencing technologies is towards generating longer and noisier reads. Evidently, accurate alignment of these reads play an important role in any downstream analysis. Similarly, reducing the overall cost of sequencing is related to the time consumption of the aligner. The tradeoff be... | ['Algorithms', 'DNA', 'DNA Copy Number Variations', 'Genome, Human', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Software'] | 28,231,760 | [['G17.035', 'L01.224.050'], ['D13.444.308'], ['G05.365.795.297.500'], ['G05.360.340.350'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.751'], ['E05.393.760.700'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Responses of neurons of the upper cervical segments of the spinal cord in the cat to stimulation of the locomotor region of the brain stem with different frequencies]. | Synaptic responses of C2 and C3 neurons to stimulation of medullary or midbrain locomotor points were recorded extracellularly in mesencephalic cats. Neurons excited with a firing index of 0.4-0.6 at a stimulation frequency of 2 S-1 retained this index at frequencies of 20-60 S-1 too. Many neurons with the low firing i... | ['Animals', 'Brain Mapping', 'Cats', 'Decerebrate State', 'Electric Stimulation', 'Locomotion', 'Medulla Oblongata', 'Reaction Time', 'Spinal Cord', 'Synapses'] | 6,621,743 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C10.597.305', 'C23.888.592.298'], ['E05.723.402'], ['G07.568.500', 'G11.427.410.568'], ['A08.186.211.132.810.591.500'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The elderly in the Italian traffic environment: analysis of mobility patterns and determinants for fatal outcomes]. | Road traffic injuries among the elderly substantially differ from those seen in younger subjects in terms of crash mechanisms and injury profile. The study aimed at analysing road traffic injuries among subjects aged over 65 in terms of the magnitude of the problem, mobility patterns and risk factors for fatal outcomes... | ['Accidents, Traffic', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Humans', 'Italy', 'Middle Aged', 'Mobility Limitation', 'Risk Factors', 'Wounds and Injuries'] | 18,478,675 | [['N06.850.135.392'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['C23.888.550'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N0... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Nucleotide pyrophosphatase/phosphodiesterase 1 is responsible for degradation of antisense phosphorothioate oligonucleotides. | The rapid degradation of unmodified phosphodiester oligodeoxynucleotides (PO-oligos) by exo -and endonucleases limits their application as antisense constructs and requires the synthesis and use of modified oligonucleotides. Phosphorothioate analogs of oligonucleotides (PS-oligos) are much more stable against nucleolyt... | ['Enzyme Inhibitors', 'Exonucleases', 'Humans', 'Immunoprecipitation', 'Oligonucleotides, Antisense', 'Phosphoric Diester Hydrolases', 'Pyrophosphatases', 'Substrate Specificity', 'Thionucleotides'] | 17,461,770 | [['D27.505.519.389'], ['D08.811.277.352.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.150.639', 'E05.478.605'], ['D13.150.480', 'D13.444.600.150.640', 'D13.695.578.424.480', 'D27.720.470.530.600.150.640'], ['D08.811.277.352.640'], ['D08.811.277.040.600'], ['G02.111.835'], ['D02.886.765', 'D13.695.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions between rainfall, deforestation and fires during recent years in the Brazilian Amazonia. | Understanding the interplay between climate and land-use dynamics is a fundamental concern for assessing the vulnerability of Amazonia to climate change. In this study, we analyse satellite-derived monthly and annual time series of rainfall, fires and deforestation to explicitly quantify the seasonal patterns and relat... | ['Brazil', 'Conservation of Natural Resources', 'Ecosystem', 'Fires', 'Greenhouse Effect', 'Rain', 'Time Factors', 'Trees'] | 18,267,907 | [['Z01.107.757.176'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['N06.230.216'], ['G16.500.175.827', 'N06.230.265'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['G01.910.857'], ['B01.650.915']] | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Sydenham's chorea is associated with decreased verbal fluency. | BACKGROUND: Sydenham's chorea (SC) is a disorder associated with rheumatic fever and related to Streptococcus-induced immune reaction cross-reactive with basal ganglia antigens. Obsessive-compulsive disorder and other behavioral abnormalities have been described in SC. There are scarce data of cognitive function in thi... | ['Adolescent', 'Basal Ganglia', 'Chorea', 'Female', 'Humans', 'Male', 'Phonetics', 'Prefrontal Cortex', 'Semantics', 'Speech Disorders'] | 16,460,985 | [['M01.060.057'], ['A08.186.211.200.885.287.249'], ['C10.228.662.262.249', 'C10.597.350.250', 'C23.888.592.350.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.518'], ['A08.186.211.200.885.287.500.270.700'], ['L01.559.598.745'], ['C10.597.606.150.500.800', 'C23.888.592.604.150.500.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Fibromuscular dysplasia unraveled: the pulsation-induced microtrauma and reactive hyperplasia theory. | INTRODUCTION: Fibromuscular dysplasia (FMD) is a relatively uncommon, non-inflammatory, non-atherosclerotic vascular condition of unknown etiology. There have been no major advancements in understanding FMD in the past 30-40yrs. We hypothesize that the vascular changes seen in FMD are a direct result of recurrent mecha... | ['Aged', 'Female', 'Fibromuscular Dysplasia', 'Humans', 'Middle Aged', 'Models, Theoretical', 'Wounds and Injuries'] | 24,810,675 | [['M01.060.116.100'], ['C14.907.137.372'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599'], ['C26']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The first record of Orthocis casey (Coleoptera: Ciidae) from the Andean region, with the description of a distinctive new species. | Orthocis Casey is recorded for the first time from the Andean Region, with the description of O. elguetai sp. nov., for which diagnostic characters and details on the male genitalia and other external morphological structures are provided. One record of the new species, from Punta Espora (Chile, higher latitude than 52... | ['Animals', 'Coleoptera', 'Demography', 'Male'] | 20,887,182 | [['B01.050'], ['B01.050.500.131.617.720.500.500.375'], ['I01.240', 'N01.224', 'N06.850.505.400']] | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Clinical study of liver resection with bipolar radiofrequency device: Habib 4X]. | OBJECTIVE: To assess the application value of a new radiofrequency device Habib 4X in liver resection.METHODS: A retrospective study was performed during March 2010 to July 2011.Forty-four patients underwent liver resection with radiofrequency device Habib 4X and another 54 patients traditional liver resection.Intraope... | ['Adult', 'Aged', 'Aged, 80 and over', 'Catheter Ablation', 'Female', 'Hepatectomy', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome'] | 24,351,595 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.808.750.500', 'E04.014.760.500'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival. | Given the importance of deregulated phosphoinositide (PI) signaling in leukemic hematopoiesis, genes coding for proteins that regulate PI metabolism may have significant and as yet unappreciated roles in leukemia. We performed a targeted knockdown (KD) screen of PI modulator genes in human acute myeloid leukemia (AML) ... | ['Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Cluster Analysis', 'Enzyme Activation', 'Gene Expression Profiling', 'Gene Knockdown Techniques', 'Humans', 'Intracellular Space', 'Leukemia, Myeloid, Acute', 'Mice', 'Mice, Transgenic', 'Neoplastic Stem Cells', 'Phosphatidylinositol P... | 24,681,948 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G02.111.263', 'G03.328'], ['E05.393.332'], ['E05.393.335.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.082.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Visible-light-induced bactericidal activity of titanium dioxide codoped with nitrogen and silver. | Titanium dioxide nanoparticles codoped with nitrogen and silver (Ag(2)O/TiON) were synthesized by the sol-gel process and found to be an effective visible light driven photocatalyst. The catalyst showed strong bactericidal activity against Escherichia coli (E. coli) under visible light irradiation (ë > 400 nm). In X-ra... | ['Anti-Infective Agents', 'Catalysis', 'Crystallography, X-Ray', 'Disinfection', 'Electron Spin Resonance Spectroscopy', 'Escherichia coli', 'Hydroxyl Radical', 'Kinetics', 'Light', 'Microbial Sensitivity Tests', 'Microbial Viability', 'Nitrogen', 'Oxidation-Reduction', 'Oxides', 'Silver', 'Silver Compounds', 'Spectrop... | 20,726,520 | [['D27.505.954.122'], ['G02.130'], ['E05.196.309.742.225'], ['N06.850.780.200.450.850.375'], ['E05.196.867.519.274'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['G01.374.661', 'G02.111.490'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Noninvasive diagnosis of vascular trauma by duplex ultrasonography. | Duplex ultrasonography was used prospectively in the initial evaluation of 198 patients with 319 potential vascular injuries of the neck and extremities. Patients who were unstable or who had obvious arterial trauma were excluded. Injury was caused by gunshot in 104 (53%), blunt trauma in 42 (21%), stab wound in 34 (17... | ['Adolescent', 'Adult', 'Aged', 'Aneurysm', 'Angiography', 'Arm', 'Arteries', 'Child', 'Female', 'Humans', 'Leg', 'Male', 'Methods', 'Middle Aged', 'Neck', 'Pulse', 'Regional Blood Flow', 'Sensitivity and Specificity', 'Thrombosis', 'Ultrasonography', 'Veins', 'Wounds, Gunshot', 'Wounds, Nonpenetrating', 'Wounds, Penet... | 1,880,842 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.907.055'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A01.378.800.075'], ['A07.015.114'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['E05.581'], ['M01.060.116.630'], ['A01.598'], ['E01.370.370.380.650', 'G09.33... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Solar activity during gestation does not affect human lifespan: evidence from national data. | Human lifespan has been reported to relate to solar activity during prenatal development. The likely key mechanism behind this association is increased mutagenic ultraviolet (UVB) radiation during high solar activity that damages DNA. Here, the aim was to replicate the findings of those previous few studies that have s... | ['Cohort Studies', 'Europe', 'Female', 'Gestational Age', 'Humans', 'Longevity', 'Male', 'Models, Statistical', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Solar Activity', 'Time Factors'] | 19,199,108 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.345.124.519', 'G07.540'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G08.686.784.769'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
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