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Prospective Evaluation of the Effect of Thigh Dissection for Removal of Transobturator Mid Urethral Slings on Refractory Thigh Pain. | PURPOSE: Transobturator slings have higher rates of de novo neurologic symptoms than retropubic slings, most commonly related to the thigh. Cases refractory to conservative management may require removal of the thigh portion of the sling. In this series we prospectively examine the effect of thigh dissection with mesh ... | ['Device Removal', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Pain Measurement', 'Pain, Postoperative', 'Prospective Studies', 'Reoperation', 'Suburethral Slings', 'Thigh', 'Time Factors', 'Urinary Incontinence, Stress', 'Urologic Surgical Procedures'] | 27,049,875 | [['E04.199'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['C23.550.767.700', 'C23.888.592.612.832'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of desferrioxamine and quercetin on hepatic ischemia-reperfusion induced renal disturbance. | BACKGROUND: The aim of this study was to analyze the effects of 45min of hepatic ischemia and 1h of reperfusion on renal oxidative stress parameters, on renal tissue damage, and the role of Desferrioxamin (Dfx) and Q on these parameters.METHODS: Thirty Wistar albino rats were randomized to five groups. Group I was the ... | ['Animals', 'Blood Urea Nitrogen', 'Creatinine', 'Deferoxamine', 'Glutathione', 'Kidney', 'Liver', 'Male', 'Malondialdehyde', 'Oxidative Stress', 'Quercetin', 'Rats', 'Rats, Wistar', 'Reperfusion Injury', 'Time'] | 16,698,257 | [['B01.050'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['D03.383.129.308.207'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['D12.644.456.448'], ['A05.810.453'], ['A03.620'], ['D02.047.700'], ['G03.673', 'G07.775.750'], ['D03.383.663.283.266.450.284.777', 'D03.633.100.150.266.450.2... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patterns of rapid diversification in heteroploid Knautia sect. Trichera (Caprifoliaceae, Dipsacoideae), one of the most intricate taxa of the European flora. | BACKGROUND: Polyploidy is one of the most important evolutionary pathways in flowering plants and has significantly contributed to their diversification and radiation. Due to the prevalence of reticulate evolution spanning three ploidy levels, Knautia is considered one of the taxonomically most intricate groups in the ... | ['Amplified Fragment Length Polymorphism Analysis', 'Balkan Peninsula', 'Biological Evolution', 'Dipsacaceae', 'Ecosystem', 'Genetic Speciation', 'Hybridization, Genetic', 'Phylogeny', 'Phylogeography', 'Plastids', 'Polyploidy'] | 27,724,874 | [['E05.393.290.382', 'E05.393.620.500.324'], ['Z01.542.101'], ['G05.045', 'G16.075'], ['B01.650.940.800.575.912.250.328.875'], ['G16.500.275.157', 'N06.230.124'], ['G05.045.350', 'G16.075.350'], ['E05.820.150.390', 'G05.090.390'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['H01.158.273.343.335.500', 'H01.277.500.589']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Flame retardants in the indoor environment -- Part II: release of VOCs (triethylphosphate and halogenated degradation products) from polyurethane. | Organophosphate esters, halogenated and non-halogenated, are frequently used for fire protection of building materials. With regard to toxicological profiles it is desired to avoid human exposure in the indoor environment. Moreover, some hazardous volatile organic compounds detected in indoor air are directly linked to... | ['Air Pollution, Indoor', 'Construction Materials', 'Environmental Monitoring', 'Flame Retardants', 'Halogens', 'Organophosphates', 'Polyurethanes', 'Volatilization'] | 12,608,925 | [['N06.850.460.100.080'], ['J01.637.241'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.720.361'], ['D01.268.380'], ['D02.705.400'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D25.720.716.650', 'J01.637.051.720.327.782', 'J01.637.051.720.716.650', 'J01.637.412.700'], ['G01.645.750', 'G02.73... | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Indole-3-acetic acid biosynthesis in the biocontrol strain Pseudomonas fluorescens Psd and plant growth regulation by hormone overexpression. | Pseudomonas fluorescens is an important biological component of agricultural soils that bestows a number of direct and indirect beneficial attributes to the plants. We analyzed the biocontrol strain P. fluorescens Psd for indole-3-acetic acid (IAA) biosynthesis and studied the effect of its consequent manipulation on i... | ['Bacterial Proteins', 'Carboxy-Lyases', 'Gene Expression', 'Gene Expression Regulation, Bacterial', 'Indoleacetic Acids', 'Pest Control, Biological', 'Plant Diseases', 'Plant Growth Regulators', 'Plant Roots', 'Pseudomonas fluorescens', 'Sorghum'] | 21,397,014 | [['D12.776.097'], ['D08.811.520.224.125'], ['G05.297'], ['G05.308.300'], ['D03.066.288', 'D03.633.100.473.404'], ['N06.850.780.200.650.650'], ['G15.610'], ['D27.505.696.377.760'], ['A18.400'], ['B03.440.400.425.625.625.325', 'B03.660.250.580.590.210'], ['B01.650.940.800.575.912.250.822.894']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ubiquitin immunoreactivity in presumed spinal interneurones in motor neurone disease. | Previous studies have demonstrated the presence of ubiquitin-immunoreactivity (Ub-IR) as inclusions and skeins in motor neurones of both the familial and sporadic forms of motor neurone disease (MND). There is evidence that interneurones also degenerate in MND, but Ub-IR in ventral horn spinal interneurones has not bee... | ['Aged', 'Amyotrophic Lateral Sclerosis', 'Anterior Horn Cells', 'Female', 'Humans', 'Immunohistochemistry', 'Interneurons', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Ubiquitin'] | 11,679,087 | [['M01.060.116.100'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['A08.186.854.729.500', 'A08.675.655.500.050', 'A11.671.655.500.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512',... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Measurement and management of work climate: cross-validation of the CRISO Psychological Climate Questionnaire. | This paper presents research results that offer answers to the "why," "what" and "how" of work climate measurement. It also submits to the scientific community a confirmatory cross-validation procedure applied to a new measurement tool, consistent with the works of Jones and James's (1979) and of Parker et al. (2003) o... | ['Attitude of Health Personnel', 'Female', 'Health Facility Environment', 'Health Personnel', 'Health Services Research', 'Hospitals, University', 'Humans', 'Male', 'Psychometrics', 'Quebec', 'Surveys and Questionnaires', 'Systems Analysis', 'Workplace'] | 19,526,889 | [['F01.100.050', 'N05.300.100'], ['N02.278.220', 'N05.300.430.400'], ['M01.526.485', 'N02.360'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.780'], ['Z01.107.567.176.791'], ['E05.318.308.980', 'N05.715.360.... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Properties of agarose-encapsulated adsorbents. II. Elimination of endogenous and exogenous phenolic compounds from human serum. | Phenolic compounds derived from the amino acid tyrosine are endogenous toxins, which are believed to be involved in the pathogenesis of hepatic coma. There are also xenobiotic phenolic substances, such as p-hydroxy-acetanilide (paracetamol or acetaminophen), which can lead to serious complications if taken in an overdo... | ['Absorption', 'Acetaminophen', 'Capsules', 'Hemoperfusion', 'Hepatic Encephalopathy', 'Humans', 'In Vitro Techniques', 'Mathematics', 'Phenols', 'Polysaccharides', 'Sepharose', 'Tyrosine'] | 7,260,233 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D26.255.150'], ['E02.870.244', 'E02.912.430', 'E04.292.510'], ['C06.552.308.500.356', 'C10.228.140.163.360', 'C18.452.132.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['H01... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The biochemical identification of fibronectin in the sea urchin embryo. | We report the biochemical identification of fibronectin in the basal lamina of the sea urchin embryo. A. punctulata gastrula stage embryos were solubilized in Triton X-100 and the insoluble basal laminae extracted by incubation in buffer containing 8M urea, 2% 2-mercaptoethanol and 2% SDS. Extracted proteins were separ... | ['Animals', 'Basement Membrane', 'Embryo, Nonmammalian', 'Fibronectins', 'Octoxynol', 'Polyethylene Glycols', 'Sea Urchins'] | 4,074,361 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['A13.350', 'A16.331'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.637.051.720.741.610'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Seizure detection in temporal lobe epileptic EEGs using the best basis wavelet functions. | In this paper, we propose a novel method using best basis wavelet functions and double thresholding that are well suited for detecting and localization of important epileptic events from noisy recorded seizure EEG signals. Our technique is based on dyadic wavelet decomposition and is mainly concerned detection of singl... | ['Adult', 'Electroencephalography', 'Epilepsy', 'Female', 'Humans', 'Male', 'Neural Networks, Computer', 'Pilot Projects', 'Signal Processing, Computer-Assisted', 'Young Adult'] | 20,703,931 | [['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.485', 'L01.224.050.375.605'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['L01.224.800'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
National survey of once-daily dosing of aminoglycoside antibiotics. | To evaluate the scope of once-daily dosing of intravenous aminoglycoside antibiotics, a questionnaire was designed and mailed to a random sample of pharmacy directors at 500 acute care hospitals in the United States. The response rate was 68.4%. Nineteen percent of the respondents reported use of once-daily dosing of a... | ['Aminoglycosides', 'Anti-Bacterial Agents', 'Drug Administration Schedule', 'Drug Utilization', 'Humans', 'Injections, Intravenous', 'Pharmacy Service, Hospital', 'Referral and Consultation', 'Surveys and Questionnaires', 'United States'] | 7,624,267 | [['D09.408.051'], ['D27.505.954.122.085'], ['E02.319.283'], ['N04.452.706.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['N02.278.216.500.968.603', 'N02.421.668.556', 'N04.452.442.452.422.603'], ['N04.452.758.849'], ['E05.318.308.980', 'N05.715.360.300.800', 'N0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia. | Cells dynamically interact throughout animal development to coordinate growth and deter disease. For example, cell-cell competition weeds out aberrant cells to enforce homeostasis. In Drosophila, tumorigenic cells mutant for the cell polarity gene scribble (scrib) are actively eliminated from epithelia when surrounded ... | ['Animals', 'Cadherins', 'Carcinogenesis', 'Clone Cells', 'Drosophila Proteins', 'Drosophila melanogaster', 'Epithelium', 'Feedback, Physiological', 'JNK Mitogen-Activated Protein Kinases', 'Models, Biological', 'Neoplasms', 'Nerve Tissue Proteins', 'Receptors, Immunologic', 'Signal Transduction', 'Up-Regulation'] | 27,997,825 | [['B01.050'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.697.098', 'C23.550.727.098'], ['A11.251.353'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['A10.272'], ['G07.410.732'], ['D08.811.913.696.620.682.700.567.374', 'D12.644.360.450.340', 'D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Feedlot performance and carcass characteristics of steers fed diets containing ammonium salts of the branched-chain fatty acids and valeric acid. | Two trials were conducted to study the effects of feeding a mixture of ammonium salts of isovaleric, 2-methylbutyric, isobutyric and valeric acids (AS-VFA) on feedlot performance and carcass characteristics of growing and finishing Angus, Hereford and Angus X Hereford steers. In trial 1,192 steers (8 steers/pen, 6 pen/... | ['Animals', 'Body Composition', 'Body Weight', 'Butyrates', 'Cattle', 'Diet', 'Fatty Acids, Volatile', 'Hemiterpenes', 'Isobutyrates', 'Pentanoic Acids', 'Quaternary Ammonium Compounds', 'Valerates'] | 4,086,403 | [['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.241.081.114', 'D10.251.400.143'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['D10.251.400'], ['D02.455.849.486'], ['D02.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minimizing 18O/16O back-exchange in the relative quantification of ribonucleic acids. | The use of isotopically labeled endonuclease digestion products allows for the relative quantification of ribonucleic acids (RNAs). This approach utilizes ribonucleases such as RNase T1 to mediate the incorporation of 18O onto the 3'-terminus of the endonuclease digestion product from a solution containing heavy water ... | ['Biocatalysis', 'Escherichia coli', 'Hydrogen-Ion Concentration', 'Hydrolases', 'Isotope Labeling', 'Oligoribonucleotides', 'Oxygen Isotopes', 'RNA, Bacterial', 'RNA, Transfer, Glu', 'Ribonuclease T1', 'Temperature', 'Time Factors', 'Water'] | 19,484,804 | [['G02.111.086', 'G02.130.500', 'G03.105'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.300'], ['D08.811.277'], ['E05.522'], ['D13.695.578.424.500'], ['D01.268.185.550.500', 'D01.362.670.300', 'D01.496.625'], ['D13.444.735.473'], ['D13.444.735.757.700.410'], ['D08.811.277.352.355.350.725', 'D08.811.27... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
'I don't want anyone to know': Experiences of obtaining access to HIV testing by Eastern European, non-European Union sex workers in Amsterdam, the Netherlands. | Historically, the Netherlands has hosted a large number of migrant sex workers. Since sex work is considered a legal profession it might serve as an example of better access to health services, including HIV testing, at least for those working within the legal framework. However, migrant sex workers, especially non-Eur... | ['Adult', 'Female', 'Focus Groups', 'HIV Infections', 'Health Personnel', 'Health Services Accessibility', 'Humans', 'Mass Screening', 'Middle Aged', 'Netherlands', 'Organizations', 'Sex Work', 'Sex Workers', 'Social Stigma', 'Stakeholder Participation', 'Transients and Migrants', 'Young Adult'] | 32,634,136 | [['M01.060.116'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['M01.526.485', 'N02.360'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Long-Term Anti-Hypertensive Therapy and Stroke Prevention: A Meta-Analysis. | BACKGROUND: Stroke causes approximately 6.7 million deaths worldwide per year and is the second leading cause of death. Pharmacotherapy for hypertension, an independent risk factor for stroke, significantly reduces the incidence of stroke. Although prior meta-analyses demonstrate various antihypertensive classes are su... | ['Adrenergic beta-Antagonists', 'Aged', 'Antihypertensive Agents', 'Blood Pressure', 'Calcium Channel Blockers', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Randomized Controlled Trials as Topic', 'Stroke'] | 26,055,616 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['H01.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Misoprostol attenuates aspirin-induced changes in potential difference and associated damage in canine gastric mucosa. | Aspirin induces ulceration, cellular exfoliation, and blood loss associated with decreases in gastric mucosal potential difference (PD). Certain prostaglandins prevent the development of experimental gastric and duodenal ulcers and modify indices related to ulceration. Misoprostol, a synthetic PGE1 derivative with gast... | ['Alprostadil', 'Animals', 'Anti-Ulcer Agents', 'Aspirin', 'DNA', 'Dogs', 'Dose-Response Relationship, Drug', 'Epithelium', 'Female', 'Gastric Mucosa', 'Gastrointestinal Hemorrhage', 'Membrane Potentials', 'Misoprostol', 'Potassium', 'Stomach Ulcer'] | 3,113,798 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['D27.505.954.483.203'], ['D02.455.426.559.389.657.410.595.176'], ['D13.444.308'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['A10.272'], ['A03.556.875.875.440', 'A10.615.550.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bronchodilator effects of terbutaline and aminophylline alone and in combination in asthmatic patients. | In 17 patients with moderate to severe asthma, we compared acute bronchodilator effects of the following drugs or drug combinations using a double-blind crossover design: terbutaline, 5; aminophyline 400; terbutaline, 5, plus aminophyline, 400; terbutaline, 2.5; aminophylline, 200; terbutaline, 2.5, plus aminophyline, ... | ['Adolescent', 'Adult', 'Aged', 'Aminophylline', 'Asthma', 'Clinical Trials as Topic', 'Double-Blind Method', 'Drug Synergism', 'Drug Therapy, Combination', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Ventilation', 'Terbutaline'] | 340,945 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.092.782.258.368.050', 'D03.633.100.759.758.824.751.075', 'D26.310.048'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differential susceptibility of na?ve and activated human gammadelta T cells to activation-induced cell death by T-cell receptor cross-linking. | BACKGROUND: T cells undergo activation-induced cell death (AICD) through repeated stimulation of their T cell receptors (TCRs). Activated human gammadelta T cells were found to die by apoptosis when their TCRs were cross-linked by antibodies, whereas na?ve gammadelta T cells freshly isolated from blood did not. Therefo... | ['Apoptosis', 'CASP8 and FADD-Like Apoptosis Regulating Protein', 'Carrier Proteins', 'Cell Cycle', 'Cell Survival', 'Cyclosporine', 'Cytokines', 'Enzyme Inhibitors', 'Fas Ligand Protein', 'Flow Cytometry', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Lymphocyte Activation', 'Membrane Glycoproteins', 'RN... | 11,778,653 | [['G04.146.954.035'], ['D12.644.360.024.285.024', 'D12.644.360.024.500.024', 'D12.644.360.075.421.024', 'D12.776.157.057.018.024', 'D12.776.476.075.421.024'], ['D12.776.157'], ['G04.144'], ['G04.346'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D27.505.519.3... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simultaneous time-lamination imaging of protein association using a split fluorescent timer protein. | Studies of temporal behaviors of protein association in living cells are crucially important for elucidating the fundamental roles and the mechanism of interactive coordination for cell activities. We developed a method for investigating the temporal alternation of a particular protein assembly using monomeric fluoresc... | ['Amino Acid Sequence', 'Animals', 'Cell Line', 'Humans', 'Luminescent Proteins', 'Models, Molecular', 'Molecular Imaging', 'Molecular Sequence Data', 'Peptide Fragments', 'Protein Multimerization', 'Protein Structure, Secondary', 'Time Factors', 'alpha-Synuclein'] | 25,679,333 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.532'], ['E05.599.595'], ['E01.370.350.557', 'E05.601.555'], ['L01.453.245.667'], ['D12.644.541'], ['G02.111.694'], ['G02.111.570.820.709.600'], ['G01.910.857'], ['D12.776.631.860.500', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Complementary and Alternative Medicine Use and Its Association with Emotional Status and Quality of Life in Patients with a Solid Tumor: A Cross-Sectional Study. | OBJECTIVES: Complementary and alternative medicine (CAM) has been used widely in various populations for various purposes, including emotional support and improvement of quality of life (QOL). However, CAM use and purposes for using CAM are less clear among Korean patients with a solid tumor. The purpose of this study ... | ['Aged', 'Anxiety', 'Complementary Therapies', 'Cross-Sectional Studies', 'Depression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Quality of Life', 'Republic of Korea', 'Surveys and Questionnaires'] | 28,453,297 | [['M01.060.116.100'], ['F01.470.132'], ['E02.190'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['Z01.252.474.557.750'], ['E05... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of high-fat, standard, and functional food meals on esophageal and gastric pH in patients with gastroesophageal reflux disease and healthy subjects. | OBJECTIVES: To investigate the effects of different test meals on esophageal and intragastric pH in patients with gastroesophageal reflux disease (GERD) and healthy subjects and to demonstrate the relationship between esophageal acid exposure (EAE) and gastric pH.METHODS: We enrolled patients with reflux esophagitis (R... | ['Adolescent', 'Adult', 'Aged', 'Case-Control Studies', 'Diet, High-Fat', 'Esophageal pH Monitoring', 'Esophagogastric Junction', 'Female', 'Functional Food', 'Gastric Acidity Determination', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Manometry', 'Middle Aged', 'Young Adult'] | 30,270,576 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.203.650.240.267'], ['E01.370.372.255', 'E01.370.520.215'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['G07.203.300.572', 'J02.500.572'], ['E01.370.225.124.300', 'E01.370.372... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets. | Poly (ADP-ribose)ylation is a dynamic protein modification that regulates multiple cellular processes. Here, we describe a system for identifying and characterizing PARylation events that exploits the ability of a PBZ (PAR-binding zinc finger) protein domain to bind PAR with high-affinity. By linking PBZ domains to bim... | ['Biosensing Techniques', 'Calcium-Binding Proteins', 'Cell Line, Tumor', 'Centrioles', 'Centrosome', 'DNA Transposable Elements', 'Epithelial Cells', 'Eukaryotic Initiation Factors', 'Fluorescent Dyes', 'Genetic Testing', 'HeLa Cells', 'Humans', 'Mitosis', 'Poly ADP Ribosylation', 'Poly Adenosine Diphosphate Ribose', ... | 29,789,535 | [['E05.601.043'], ['D12.776.157.125'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.214.190.750.585.160.130', 'A11.284.430.214.190.750.820.500.500.130'], ['A11.284.430.214.190.750.585.160', 'A11.284.430.214.190.750.820.500.500'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Parameters controlling the rate of gene targeting frequency in the protozoan parasite Leishmania. | In this study we investigated the role of several parameters governing the efficiency of gene targeting mediated by homologous recombination in the protozoan parasite Leishmania. We evaluated the relative targeting frequencies of different replacement vectors designed to target several sequences within the parasite gen... | ['Animals', 'DNA, Protozoan', 'Gene Dosage', 'Gene Targeting', 'Genetic Vectors', 'Kanamycin Kinase', 'Leishmania', 'Nucleic Acid Heteroduplexes', 'Recombination, Genetic', 'Sequence Homology, Nucleic Acid', 'Species Specificity'] | 9,336,458 | [['B01.050'], ['D13.444.308.442'], ['G05.380.350'], ['E05.393.335'], ['G05.360.337'], ['D08.811.913.696.620.475'], ['B01.268.475.868.488'], ['D13.444.500'], ['G05.728'], ['G02.111.810.550', 'G05.810.550'], ['G16.824']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of biodegradable controlled release rod systems for pain relief applications. | Control of chronic, severe pain is a difficult and important clinical problem for most patients, especially those with cancer. Although current applications are insufficient for a satisfactory solution to this problem, the rate of disease incidence is increasing worldwide, thus making the problem more apparent. Based o... | ['Analgesics, Opioid', 'Biocompatible Materials', 'Biodegradation, Environmental', 'Codeine', 'Drug Delivery Systems', 'Hydromorphone', 'Kinetics', 'Lactic Acid', 'Microscopy, Electron, Scanning', 'Morphine', 'Pain', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Polymers', 'Time Factors'] | 12,003,071 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D03.132.577.249.562.149', 'D03.605.497.607.204', 'D03.633.400.686.607.204', 'D04.615.723.795... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The effect of socio-economic status and ethnicity on the comparative oral health of Asian and White Caucasian 12-year-old children. | OBJECTIVE: To investigate the oral health of 12-year-old children of different deprivation but similar fluoridation status from South Asian and White Caucasian ethnic groups.DESIGN: An epidemiological survey of 12-year-old children using BASCD criteria, with additional tooth erosion, ethnic classification and postcode ... | ['Asian Continental Ancestry Group', 'Child', 'DMF Index', 'Dental Caries', 'Dentition, Permanent', 'England', 'European Continental Ancestry Group', 'Female', 'Hinduism', 'Humans', 'Islam', 'Male', 'Oral Health', 'Prevalence', 'Reproducibility of Results', 'Sampling Studies', 'Social Class', 'Tooth Erosion', 'Tooth, D... | 16,161,880 | [['M01.686.508.200'], ['M01.060.406'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['C07.793.720.210'], ['A14.549.167.237'], ['Z01.542.363.300'], ['M01.686.508.400'], ['K01.844.231'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Interaction Between Personality, Pain, and Genes in Ischemic Heart Disease]. | Personality traits of the patient with ischemic heart disease (IHD) are thought to determine disease course. Their level depends on clinical presentations of IHD including the presence of cardiac pain. The aim of the study was to identify the modifying effect of genes coding for serotonin transporter (5-HTTLPR), seroto... | ['Age Factors', 'Aged', 'Alleles', 'Brain-Derived Neurotrophic Factor', 'Coronary Artery Disease', 'Heterozygote', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Pain', 'Personality', 'Polymorphism, Genetic', 'Serotonin Plasma Membrane Transport Proteins'] | 28,290,902 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Respiratory quinones in Archaea: phylogenetic distribution and application as biomarkers in the marine environment. | The distribution of respiratory quinone electron carriers among cultivated organisms provides clues on both the taxonomy of their producers and the redox processes these are mediating. Our study of the quinone inventories of 25 archaeal species belonging to the phyla Eury-, Cren- and Thaumarchaeota facilitates their us... | ['Archaea', 'Bacteria', 'Biomarkers', 'Biomass', 'Black Sea', 'Ecology', 'Gene Transfer, Horizontal', 'Membrane Lipids', 'Oxidation-Reduction', 'Phylogeny', 'Quinones', 'Terpenes'] | 26,472,620 | [['B02'], ['B03'], ['D23.101'], ['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.756.217'], ['H01.158.273.248', 'H01.277.249'], ['G05.728.390'], ['D10.570'], ['G02.700', 'G03.295.531'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D02.806'], ['D02.455.849']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
A double-masked, placebo-controlled trial of acyclovir cream in immunocompetent patients with herpes zoster. | Sixty-four patients with herpes zoster were entered into a randomised double-masked, placebo-controlled trial of 5% acyclovir cream applied five times daily for 5 days. Of these patients, 56 were included in the final analysis (26 acyclovir, 30 placebo). Significant and objective differences in either progression of th... | ['Acyclovir', 'Aged', 'Aged, 80 and over', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Herpes Zoster', 'Humans', 'Male', 'Middle Aged', 'Ointments', 'Random Allocation'] | 3,060,542 | [['D03.633.100.759.758.399.454.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C01.925.256.466.930.750'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of high pressure treatment on metabolite profile of marinated meat in soy sauce. | Marinated meat in soy sauce was produced using hind leg by washing, rubbing salt, marinating with soy sauce and spices, and air dry-ripening for 15d. The effect of high pressure (HP) (150 and 300MPa for 15min) on the metabolite profiles of products was characterized using 1H NMR and multivariate data analysis. The resu... | ['Meat', 'Pressure', 'Sodium Chloride', 'Soy Foods'] | 28,946,326 | [['G07.203.300.600', 'J02.500.600'], ['G01.374.715'], ['D01.210.450.150.875', 'D01.857.650'], ['G07.203.200.775', 'G07.203.300.850.450.500', 'J02.350.775', 'J02.500.850.800.500']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Making a difference: initiating and maintaining a faith-based free health clinic. | This article is a summary of the challenges, struggles, and barriers that a group of churches encountered in developing a faith-based free health clinic. From the inception, this clinic has existed for the uninsured whose total household income aligns with the 2009 Fedral Poverty Guidelines. A voluntary interview with ... | ['Alabama', 'Ambulatory Care Facilities', 'Humans', 'Medical Indigency', 'Medically Uninsured', 'Organizational Case Studies', 'Program Development', 'Religion and Medicine', 'Uncompensated Care', 'Volunteers'] | 19,752,636 | [['Z01.107.567.875.075.100', 'Z01.107.567.875.750.100'], ['N02.278.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.460', 'N03.219.780'], ['M01.385'], ['N03.349.380.710', 'N05.715.360.455'], ['N04.452.760'], ['K01.844.619'], ['N04.590.374.900', 'N05.300.830'], ['M01.955']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A prospective evaluation of outcomes of two tapered implant systems. | The purpose of this prospective clinical study was to evaluate survival rate (SVR - i.e. fixtures still in place at the end of the observation period) and success rate (SCR - i.e. bone resorption around the implant neck) of two tapered implant systems. Both systems were equipped with a tapered connection, one requiring... | ['Alveolar Bone Loss', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Prosthesis Design', 'Dental Restoration Failure', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Treatment Outcome'] | 27,469,541 | [['C05.116.264.150', 'C07.465.714.354.500'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.625', 'E06.912.145'], ['E06.323.400', 'E06.780.346.725'], ['E05.318.372.500.750.249', 'N05.715.360.33... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Induction chemotherapy followed by cisplatin or cetuximab concomitant to radiotherapy for laryngeal/hypopharyngeal cancer: Long-term results of the TREMPLIN randomised GORTEC trial. | BACKGROUND: In Europe, induction chemotherapy (ICT) followed by radiotherapy is preferred to conventional chemoradiotherapy to avoid total laryngectomy in patients with laryngeal/hypopharyngeal cancer. In comparison with conventional radiotherapy, bioradiotherapy with cetuximab significantly improves locoregional contr... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Squamous Cell', 'Cetuximab', 'Chemoradiotherapy, Adjuvant', 'Cisplatin', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'France', 'Humans', 'Hypopharyngeal Neoplasms', 'Induction Chemotherapy', 'Laryngeal Neopl... | 32,454,417 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.124.486.485.114.224.060.750', 'D12.776.124.790.651.114.224.060.750', 'D12.776.377.715.548.114.224.200.750'], ['E02.186.079.500', 'E02.319.164.500',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Comparison and discussion of different surgical methods used to treat vesicovaginal fistulas]. | OBJECTIVE: To compare the feasibility and prognosis of different surgical methods used for vesicovaginal fistulas and to explore the value of electrocoagulation treating small ones.METHODS: The medical data of 19 patients who had undertaken transvaginal VVF repairs in Peking University People's Hospital between October... | ['Adult', 'Female', 'Gynecologic Surgical Procedures', 'Humans', 'Laparoscopy', 'Middle Aged', 'Retrospective Studies', 'Vesicovaginal Fistula'] | 29,045,975 | [['M01.060.116'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selection of DNA aptamers to Streptococcus pneumonia and fabrication of graphene oxide based fluorescent assay. | Pneumococci are one of the leading causes of infections throughout the world causing problems mainly in children, elderly, and immune-deficient patients. In recent years antibiotic resistant Streptococcus pneumoniae strains become widespread. Therefore simple, rapid, and specific detection methods are needed for public... | ['Aptamers, Nucleotide', 'Flow Cytometry', 'Graphite', 'Humans', 'Molecular Probes', 'SELEX Aptamer Technique', 'Spectrometry, Fluorescence', 'Streptococcus pneumoniae'] | 29,964,028 | [['D13.695.578.424.224'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D01.268.150.300', 'D01.578.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.259.750', 'D27.720.470.530']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of growth rate and nutrient limitation on the transformability of Escherichia coli with plasmid deoxyribonucleic acid. | The observed transformation frequency by plasmid deoxyribonucleic acid of Escherichia coli grown in continuous culture was found to depend on both the steady-state growth rate and the type of nutrient used to limit growth. With carbon, nitrogen, or phosphorus limitation, the faster the growth rate, the higher the trans... | ['Calcium Chloride', 'Culture Media', 'DNA, Bacterial', 'Dose-Response Relationship, Drug', 'Escherichia coli', 'Glucose', 'Magnesium', 'Nitrogen', 'Phosphates', 'Plasmids', 'Sulfates', 'Transformation, Bacterial'] | 7,016,833 | [['D01.146.300', 'D01.210.450.150.150'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['G07.690.773.875', 'G07.690.936.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D09.947.875.359.448'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D01.268.604', 'D01.362.625'], ['D01.029.260.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mercury water and cauterizing stones: Nicolas Andr? and tic douloureux. | In his 1756 text, Observations pratiques sur les maladies de l'ur?thre et sur plusiers faits convulsifs, Nicolas Andr? coined the term "tic douloureux." He believed that this pain originated from compression of facial sensory peripheral nerves. Using scientific observation and experimentation to confirm this hypothesis... | ['Cautery', 'France', 'History, 18th Century', 'Humans', 'Mercury', 'Solutions', 'Trigeminal Neuralgia'] | 10,223,470 | [['E02.154', 'E04.014.170'], ['Z01.542.286'], ['K01.400.504.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D26.776'], ['C07.465.299.625.500.700', 'C10.292.319.625.700.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Detection of noncovalent complex between alpha-amylase and its microbial inhibitor tendamistat by electrospray ionization mass spectrometry. | Electrospray ionization mass spectrometry (ESI-MS) is now routinely used for detection of noncovalent complexes. However, detection of noncovalent protein-protein complexes is not a widespread practice and still produces some challenges for mass spectrometrists. Here we demonstrate the detection of a noncovalent protei... | ['Animals', 'Chromatography, Liquid', 'Enzyme Inhibitors', 'Models, Structural', 'Molecular Weight', 'Peptides', 'Protein Binding', 'Protein Conformation', 'Spectrometry, Mass, Electrospray Ionization', 'Swine', 'alpha-Amylases'] | 11,180,535 | [['B01.050'], ['E05.196.181.400'], ['D27.505.519.389'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['G02.494'], ['D12.644'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['E05.196.566.600'], ['B01.050.150.900.649.313.500.880'], ['D08.811.277.450.066.050']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Isolation of a unique marine bacterium capable of growth on a wide variety of polysaccharides from macroalgae. | A unique marine bacterium has been isolated which can be cultured on a variety of polysaccharides and cell wall preparations from red and brown algae. | ['Eukaryota', 'Gram-Negative Aerobic Bacteria', 'Hydrolysis', 'Phaeophyta', 'Polysaccharides', 'Seawater', 'Water Microbiology'] | 736,549 | [['B01'], ['B03.440.400'], ['G02.380'], ['B01.750.600'], ['D09.698'], ['G16.500.275.725.500'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Infectivity of different forms of lambda bacteriophage DNA in transfection of calcinated Escherichia coli]. | Infectivity of linear lambdaDNA molecules is proved to be about a hundred times higher in calcinated E. coli K12 (lambai434) than in E. coli K12(lambda-): the levels of transfection were 1-3-10(7) and 1-2-10(5) infective centers per 1 mug DNA, respectively. In E. coli JC 5743 rec B21 defective for exonucleases I and V ... | ['Coliphages', 'DNA, Viral', 'Escherichia coli', 'Lysogeny', 'Mutation', 'Species Specificity', 'Transformation, Genetic', 'Virus Replication'] | 765,769 | [['B04.123.205'], ['D13.444.308.568'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.935.500', 'G06.920.877.500'], ['G05.365.590'], ['G16.824'], ['G05.728.865'], ['G06.920.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Role of Socioeconomic Status and Health Care Access in Breast Cancer Screening Compliance Among Hispanics. | OBJECTIVES: Considerable disparities in breast cancer screening exist between Hispanic and non-Hispanic white (NHW) women. Identifying and quantifying the factors contributing to these racial-ethnic disparities can help shape interventions and policies aimed at reducing these disparities. This study, for the first time... | ['Adult', 'Aged', 'Breast Neoplasms', 'Early Detection of Cancer', 'Female', 'Health Services Accessibility', 'Healthcare Disparities', 'Hispanic Americans', 'Humans', 'Mammography', 'Middle Aged', 'Patient Compliance', 'Retrospective Studies', 'Risk Factors', 'Social Class', 'United States'] | 25,756,197 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E01.390.500'], ['N04.590.374.350', 'N05.300.430'], ['N04.590.374.380', 'N05.300.493'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adolescents initiating cannabis use: cultural opposition or poor mental health? | In Norway, the use of cannabis was introduced by a resourceful group of oppositional middle-class adolescents in the late 1960s. At the beginning of the 1970s there were, however, signs of a change in the recruitment of the users: youths in trouble from lower social levels gradually started to use the drug. In a prospe... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Attitude', 'Family', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Marijuana Abuse', 'Mental Disorders', 'Multivariate Analysis', 'Norway'] | 2,074,287 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['F01.100'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C25.775.635', 'F03.900.635'], ['F03'], ['E05.318.740.150.500', 'N05.715.360.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Early results of the EORTC randomized clinical trial on multiple fractions per day (MFD) and misonidazole in advanced head and neck cancer. | From Feb. 1981 to Oct. 1984, a randomized clinical trial was carried out in the EORTC Radiotherapy Group, comparing classical radiotherapy 70 Gy/7 weeks to MFD (3 X 1.6 Gy/day for 10 days, 3 weeks rest, followed by a boost to 67.2 or 72 Gy), with or without Misonidazole (1 g/m2 every irradiation day, total 12 to 14 g/m... | ['Adult', 'Aged', 'Clinical Trials as Topic', 'Combined Modality Therapy', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Misonidazole', 'Neoplasm Recurrence, Local', 'Prognosis', 'Radiotherapy', 'Radiotherapy Dosage', 'Random Allocation'] | 3,516,953 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.186'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.640.672.530', 'D03.383.129.308.658.530'], ['C04.697.655', 'C23.550.727.655'], ['E01.789'], ['E02... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Protective effect of heme oxygenase-1 induction in vivo to pancreas islet xenograft]. | OBJECTIVE: To study the protective effect of islet xenograft and its possible mechanism of high expression of heme oxygenase-1 (HO-1) in donor pancreas islet induced by cobalt protoporphyrin (CoPP).METHODS: Male SD rats and C57BL/6 mouse were used as donors and recipients respectively. Donors were divided into 3 groups... | ['Animals', 'Diabetes Mellitus, Experimental', 'Graft Survival', 'Heme Oxygenase-1', 'Interleukin-10', 'Islets of Langerhans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Pancreas Transplantation', 'Protoporphyrins', 'Rats', 'Rats, Sprague-Dawley', 'Subrenal Capsule Assay', 'Transplantation, Heterologous'] | 19,781,175 | [['B01.050'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G12.875.545.340'], ['D08.811.682.690.708.410.500'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['A03.734.414', 'A06.300.414'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Reporting costs" to nonoffending parents in cases of intrafamilial child sexual abuse. | Findings from a study of 104 nonoffending parents and their sexually abused children suggest four areas in which nonoffending parents experience significant change or loss as a result of the disclosure of the sexual abuse of their children. The term reporting cost was coined to describe these changes and losses. The fo... | ['Adult', 'Child', 'Child Abuse, Sexual', 'Cost of Illness', 'Cross-Sectional Studies', 'Female', 'Humans', 'Incest', 'Life Change Events', 'Male', 'Mandatory Reporting', 'Parents', 'Surveys and Questionnaires', 'Truth Disclosure'] | 9,666,550 | [['M01.060.116'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Planning target margin calculations for prostate radiotherapy based on intrafraction and interfraction motion using four localization methods. | PURPOSE: To determine planning target volume (PTV) margins for prostate radiotherapy based on the internal margin (IM) (intrafractional motion) and the setup margin (SM) (interfractional motion) for four daily localization methods: skin marks (tattoo), pelvic bony anatomy (bone), intraprostatic gold seeds using a 5-mm ... | ['Dose Fractionation, Radiation', 'Gold', 'Humans', 'Male', 'Movement', 'Pelvic Bones', 'Prostate', 'Prostatic Neoplasms', 'Prostheses and Implants'] | 17,919,837 | [['E02.815.639.200'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['A02.835.232.043.825'], ['A05.360.444.575', 'A10.336.707'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E07.695']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Total laparoscopic hysterectomy in 1253 patients using an early ureteral identification technique. | AIM: The aim of this study was to determine the incidence of perioperative complications and evaluate risk factors for the major complications of total laparoscopic hysterectomy (TLH) using an early ureteral identification technique. We describe the technique we standardized and used for TLH, without exclusion criteria... | ['Adult', 'Female', 'Humans', 'Hysterectomy, Vaginal', 'Incidence', 'Japan', 'Laparoscopy', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Risk Factors', 'Ureter'] | 22,540,927 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399.380'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.252.474.463', 'Z01.639.595'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['C23.550.767... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Detection of Hypoderma actaeon infestation in Cervus elaphus with ELISA and western blotting. | We used enzyme-linked immunosorbent assay (ELISA) and western blotting (WB) to evaluate the reactivity of first-stage larval extracts of Hypoderma lineatum with antibodies in sera from 76 red deer from an endemic area for Hypoderma actaeon. Antibodies in sera from deer infested with H. actaeon recognized hypodermin C f... | ['Animals', 'Animals, Wild', 'Antibodies', 'Blotting, Western', 'Deer', 'Diptera', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Larva', 'Male', 'Myiasis', 'Seroepidemiologic Studies'] | 20,688,700 | [['B01.050'], ['B01.050.050.300'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.050.150.900.649.313.500.380.373'], ['B01.050.500.131.617.720.500.500.750'], ['E05.478.566.350.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum | Concurrently, leishmaniasis and AIDS are global public health issues and the overlap between these diseases adds additional treats to the management of co-infected patients. Lopinavir (LPV) has a well characterized anti-HIV and leishmanicidal action, and to analyze its combined action with miltefosine (MFS) could help ... | ['Administration, Oral', 'Animals', 'Antiprotozoal Agents', 'Coinfection', 'Disease Models, Animal', 'Drug Combinations', 'Drug Synergism', 'Female', 'HIV Infections', 'Inhibitory Concentration 50', 'Leishmania infantum', 'Leishmaniasis, Visceral', 'Liver', 'Lopinavir', 'Macrophages, Peritoneal', 'Mice', 'Mice, Inbred ... | 31,316,919 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.122.250.100'], ['C01.218'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D26.310'], ['G07.690.773.968.477'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['E05.940.350', 'G07.690.936.563']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Small-dose bupivacaine-sufentanil prevents cardiac output modifications after spinal anesthesia. | Spinal injection of small-dose (SD) bupivacaine decreases the likelihood of hypotension compared with large-dose (LD) bupivacaine. We assumed that a SD of bupivacaine could also prevent the decrease in cardiac output (CO). Patients undergoing elective urologic, lower abdominal, or lower limb surgery under spinal anesth... | ['Adult', 'Aged', 'Anesthesia, Spinal', 'Bupivacaine', 'Cardiac Output', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Sufentanil'] | 16,244,022 | [['M01.060.116'], ['M01.060.116.100'], ['E03.155.086.331'], ['D02.065.199.239', 'D02.092.146.113.239'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Left atrial volume and strain parameters using echocardiography in a black population. | Aims: Left atrial (LA) volume is an important predictor of morbidity and mortality in cardiovascular disease. Left atrial strain is a feasible technique for assessing LA function. The EchoNoRMAL study recently highlighted the possibility that ethnic-based differences may exist in LA size. There is a paucity of data reg... | ['Adult', 'African Continental Ancestry Group', 'Age Factors', 'Analysis of Variance', 'Cross-Sectional Studies', 'Echocardiography, Doppler', 'Female', 'Heart Atria', 'Humans', 'Hypertrophy', 'Image Interpretation, Computer-Assisted', 'Linear Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Observer Variation... | 27,044,915 | [['M01.060.116'], ['M01.686.508.100'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Association of single nucleotide polymorphism of reduced folate carrier gene with susceptibility to acute leukemia]. | OBJECTIVE: To investigate the allele and genotype frequencies of reduced folate carrier gene (RFC) 80G/A polymorphism in Chinese patients with acute leukemia (AL) and healthy control children, and to provide clue for association between the single nucleotide polymorphism (SNP) of RFC and the occurrence of AL.METHODS: B... | ['Acute Disease', 'Adolescent', 'Base Sequence', 'Child', 'Child, Preschool', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'Infant', 'Infant, Newborn', 'Leukemia', 'Male', 'Polymorphism, Single Nucleotide', 'Reduced Folate Carrier Protein', 'Sequence Analysis, DNA'] | 21,811,990 | [['C23.550.291.125'], ['M01.060.057'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406'], ['M01.060.406.448'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C04.557.337'], ['G05.365.795.598'], ['D12.... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
MASP-1 of the complement system promotes clotting via prothrombin activation. | Mannan-binding lectin-associated serine protease-1 (MASP-1), a protein of the complement lectin pathway, resembles thrombin in terms of structural features and substrate specificity, and it has been shown to activate coagulation factors. Here we studied the effects of MASP-1 on clot formation in whole blood (WB) and pl... | ['Blood Coagulation', 'Enzyme Activation', 'Female', 'Humans', 'Male', 'Mannose-Binding Protein-Associated Serine Proteases', 'Proteolysis', 'Prothrombin', 'Thrombelastography'] | 25,745,807 | [['G09.188.390.150'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.501', 'D08.811.277.656.959.350.501', 'D12.776.124.486.274.045.387.875'], ['G02.111.720', 'G03.812'], ['D08.622.709', 'D12.776.124.125.800', 'D12.776.811.243.709', 'D23.119.945'], ['E01.370.225.62... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characteristics of regional myocardial stunning after exercise in dogs with chronic coronary stenosis. | Persistent impairment of regional contraction of the left ventricle after restoration of blood flow following transient coronary occlusion has been termed "stunning," and reversible regional dysfunction has also been observed during recovery from exercise-induced regional ischemia. To determine whether limitation of su... | ['Animals', 'Chronic Disease', 'Coronary Circulation', 'Coronary Disease', 'Dogs', 'Heart', 'Hemodynamics', 'Physical Exertion'] | 2,750,931 | [['B01.050'], ['C23.550.291.500'], ['G09.330.100.324'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['G09.330.380'], ['G11.427.683']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro and in vivo analysis of the processing and fate of the peptide products of the short proopiomelanocortin mRNA. | Many peripheral tissues express the proopiomelanocortin (POMC) gene as an 800-base mRNA that lacks the 5' end of the 1200-base pituitary transcript. The missing region encodes the peptide signal sequence, and thus, it is unlikely that any translation product would be secreted. We have found that a RNA transcript equiva... | ['Adrenocorticotropic Hormone', 'Animals', 'Cell Line', 'DNA', 'Drug Resistance', 'Gene Expression Regulation', 'Microsomes', 'Neomycin', 'Pro-Opiomelanocortin', 'Promoter Regions, Genetic', 'RNA Processing, Post-Transcriptional', 'RNA, Messenger', 'Rabbits', 'Rats', 'Reticulocytes', 'beta-Endorphin'] | 2,177,842 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['A11.251.210'], ['D13.444.308'], ['G07.690.773.984'], ['G05.308'], ['A11.284.835.540'], ['D09.408.051.623... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of moderate hypoxia/reoxygenation on mitochondrial adaptation to acute severe hypoxia. | In an experimental model, it was shown that repetitive periods of hypoxia/reoxygenation (H/R) [5 cycles of 5 min hypoxia (12% O(2) in N(2) ) followed by 15 min normoxia, daily for three weeks] attenuated basal and stimulated in vitro lipid peroxidation, as well as H(2)O(2) production in liver and brain mitochondria of ... | ['Animals', 'Antioxidants', 'Brain', 'Glutathione', 'Glutathione Peroxidase', 'Glutathione Transferase', 'Homeostasis', 'Hypoxia', 'Lipid Peroxidation', 'Liver', 'Mitochondria', 'Models, Biological', 'NADP', 'Oxidative Stress', 'Oxygen', 'Rats', 'Rats, Wistar', 'Superoxide Dismutase'] | 19,584,028 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A08.186.211'], ['D12.644.456.448'], ['D08.811.682.732.500'], ['D08.811.913.225.500'], ['G07.410'], ['C23.888.852.079'], ['G02.111.515', 'G03.295.531.587'], ['A03.620'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['E05.599.395'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of adult participation in a school-based family intervention to improve Children's diet and physical activity: the Child and Adolescent Trial for Cardiovascular Health. | UNLABELLED: BACKGROUND. There are strong theoretical reasons for including a family component with a school-based intervention aimed at eating, activity, and smoking behaviors, but the empirical findings to date are limited and show mixed results. The overall CATCH family intervention added only knowledge and attitudin... | ['Adolescent', 'Adult', 'Cardiovascular Diseases', 'Child', 'Diet', 'Exercise', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Promotion', 'Humans', 'Male', 'Parents', 'Program Evaluation', 'Regression Analysis', 'School Health Services', 'United States'] | 8,818,068 | [['M01.060.057'], ['M01.060.116'], ['C14'], ['M01.060.406'], ['G07.203.650.240'], ['G11.427.410.698.277', 'I03.350'], ['F01.100.150.500', 'N05.300.150.410'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Occupational and recreational physical activity during adult life and the risk of cancer among men. | BACKGROUND: There is a strong evidence for a protective role of physical activity (PA) on cancers of the colon, breast (postmenopausal) and endometrium, but data are less consistent or scarce for other cancer types. This study assessed the relationship between occupational and recreational PA and cancer risk among men ... | ['Adult', 'Canada', 'Case-Control Studies', 'Humans', 'Male', 'Middle Aged', 'Motor Activity', 'Neoplasms', 'Occupations', 'Recreation', 'Risk Factors'] | 21,030,330 | [['M01.060.116'], ['Z01.107.567.176'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.145.632', 'G11.427.410.698'], ['C04'], ['N01.824.547'], ['I03.450.642'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Mechanical circulatory supports for the treatment of advanced heart failure]. | Heart failure (HF) is the final event of virtually all cardiac diseases with a prevalence that has risen to epidemic levels in both Europe and North America. Medical therapy with angiotensin-converting enzyme inhibitors, beta-blockers, and aldosterone inhibitors associated with cardiac resynchronization therapy, when i... | ['Disease Progression', 'Heart Failure', 'Heart Transplantation', 'Heart-Assist Devices', 'Humans', 'Time Factors', 'Ventricular Remodeling'] | 19,195,316 | [['C23.550.291.656'], ['C14.280.434'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.857'], ['C23.300.985', 'G09.330.955.975']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Baroreflex control of sympathetic outflow in pregnant rats: effects of captopril. | Arterial baroreflex control of renal sympathetic nerve activity (RSNA) was compared in nonpregnant (NP) and near-term pregnant (P) chloralose-anesthetized rats. Baroreflex curves were obtained by recording reflex changes in RSNA (expressed as a percent of base line) due to increases and decreases in mean arterial press... | ['Animals', 'Blood Pressure', 'Captopril', 'Female', 'Pregnancy', 'Pregnancy, Animal', 'Pressoreceptors', 'Rats', 'Rats, Inbred Strains', 'Reflex', 'Sympathetic Nervous System'] | 2,193,548 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D12.125.072.401.623.270'], ['G08.686.784.769'], ['G08.686.784.769.498'], ['A08.675.650.915.750.750', 'A08.800.050.800.900.700', 'A08.800.950.750.750', 'A11.671.650.915.750.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multidirectional voluntary glenohumeral dislocation in a 7-year-old patient: a case report. | A case of multidirectional voluntary shoulder dislocation developing at the age of seven is reported. The authors present the process that leads to the diagnosis of voluntary shoulder dislocation. The treatment of young patients with this condition is difficult. If no underlying pathology exists, most authors agree it ... | ['Child', 'Diagnosis, Differential', 'Humans', 'Male', 'Orthopedic Procedures', 'Physical Therapy Modalities', 'Risk Factors', 'Shoulder Dislocation'] | 14,748,116 | [['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718', 'E04.555'], ['E02.779', 'E02.831.535'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['C05.550.518.750', 'C26.289.750', 'C26.803.125']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Body weight and waist circumference as predictors of vitamin D deficiency in patients with type 2 diabetes and cardiovascular disease. | BACKGROUND/AIM: Vitamin D deficiency is a well-established risk factor for bone disease, but emerging data suggest that altered vitamin D homeostasis may play a role in the development of type 2 diabetes mellitus (T2DM), dyslipidemia hypertension, and other cardiovascular diseases (CVD). The aim of this study was to in... | ['Body Mass Index', 'Body Weight', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Lipid A', 'Male', 'Middle Aged', 'Risk Factors', 'Vitamin D Deficiency', 'Waist Circumference'] | 23,607,183 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C14'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Human milk stimulates DNA synthesis and cellular proliferation in cultured fibroblasts. | Human milk contains a mitogenic factor that stimulates DNA synthesis and cell division in mouse and human fibroblasts in vitro. Milk at a concentration of 1% (vol/vol) is as active in stimulating DNA synthesis as is 5% (vol/vol) human serum and 10% (vol/vol) calf serum. The mitogenic activity of human milk is destroyed... | ['Cell Division', 'Cells, Cultured', 'Chymotrypsin', 'DNA', 'Fibroblasts', 'Growth Substances', 'Isoelectric Point', 'Milk, Human', 'Molecular Weight', 'Trypsin'] | 283,415 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['D13.444.308'], ['A11.329.228'], ['D27.505.696.377'], ['E05.301.300.663.500', 'G02.300.500'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300.350.52... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Type 2 myocardial infarction among critically ill elderly patients in the Intensive Care Unit: the clinical features and in-hospital prognosis. | BACKGROUND: Type 2 myocardial infarction (T2MI) refers to myocardial ischemic necrosis as a result of myocardial oxygen supply/demand mismatch, which are common comorbidities of critically ill patients. The purpose of this study was to investigate the incidence rate and risks of T2MI in critically ill elderly patients ... | ['Aged', 'Critical Illness', 'Hospitals', 'Humans', 'Intensive Care Units', 'Myocardial Infarction', 'Prognosis'] | 31,598,913 | [['M01.060.116.100'], ['C23.550.291.625'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['E01.789']] | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased severity of experimental colitis in alpha 5 nicotinic acetylcholine receptor subunit-deficient mice. | Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue a... | ['Animals', 'Colitis', 'Mice', 'Mice, Knockout', 'Receptors, Nicotinic'] | 15,973,160 | [['B01.050'], ['C06.405.205.265', 'C06.405.469.158.188'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['D12.776.157.530.400.400.100.500', 'D12.776.543.550.450.500.100.500', 'D12.776.543.58... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Robust colour constancy in red-green dichromats. | Colour discrimination has been widely studied in red-green (R-G) dichromats but the extent to which their colour constancy is affected remains unclear. This work estimated the extent of colour constancy for four normal trichromatic observers and seven R-G dichromats when viewing natural scenes under simulated daylight ... | ['Adult', 'Color Perception', 'Contrast Sensitivity', 'Female', 'Humans', 'Male', 'Middle Aged', 'Photic Stimulation', 'Sensory Thresholds', 'Young Adult'] | 28,662,218 | [['M01.060.116'], ['F02.463.593.932.217'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.723.729'], ['F02.463.593.710'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of histamine H(3) receptor activation on the behavioral-stimulant effects of methamphetamine and cocaine in mice and squirrel monkeys. | BACKGROUND: Cocaine and methamphetamine (METH) are two commonly abused drugs that have behavioral-stimulant properties. These stimulant effects are partially mediated by the dopaminergic system. Recent evidence has suggested that the histamine H(3) receptor (H(3)R) may modulate the release of dopamine induced by METH. ... | ['Animals', 'Behavior, Animal', 'Central Nervous System Stimulants', 'Cocaine', 'Conditioning, Operant', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Histamine Agonists', 'Imidazoles', 'Male', 'Methamphetamine', 'Mice', 'Motor Activity', 'Receptors, Histamine H3', 'Reinforcement Schedule', 'Saimiri', 'Thio... | 19,145,102 | [['B01.050'], ['F01.145.113'], ['D27.505.696.282', 'D27.505.954.427.220'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['F02.463.425.179.509'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['D27.505.519.625.375.400', 'D27.505.696.577.375.400'], ['D03.383.129... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of glucose kinetics in trauma patients by insulin and glucagon. | The current study was undertaken to evaluate the contribution of insulin and glucagon to regulation of glucose metabolism in man following severe, traumatic injury by manipulating concentrations of insulin and glucagon with infusions of somatostatin. Glucose kinetics were assessed with [U-14C, 6-(3)H]glucose in severel... | ['Adolescent', 'Adult', 'Energy Metabolism', 'Female', 'Glucagon', 'Glucose', 'Humans', 'Insulin', 'Lipid Metabolism', 'Liver', 'Male', 'Middle Aged', 'Somatostatin', 'Wounds and Injuries'] | 1,347,143 | [['M01.060.057'], ['M01.060.116'], ['G03.295'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.458'], ['A03.620'], ['M01.060.116.630'], ['D06.472.699.327.700.875', 'D0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors for secondary transmission in households after a common-source outbreak of Norwalk gastroenteritis. | In November 1984, a foodborne outbreak of Norwalk gastroenteritis occurred in a K-12 public school in northern Vermont. The outbreak offered an opportunity to systematically study in detail secondary transmission rates in households. Eating salad at Tuesday's school-sponsored Thanksgiving Banquet was associated with il... | ['Adult', 'Age Factors', 'Child', 'Child, Preschool', 'Disease Outbreaks', 'Female', 'Food Contamination', 'Gastroenteritis', 'Humans', 'Norwalk virus', 'Risk Factors', 'Schools', 'Vermont', 'Virus Diseases'] | 2,825,520 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.290'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['C06.405.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.578.298.550.500'], ['E05.318.740.600.800.725', 'N05.715.... | ['Named Groups [M]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
A case-control for the association between change in weight, family history and hypertension at different ages. | To study the association between the changes of weight, family history and hypertension at different ages, a pair-matched case-control study was conducted in the outpatient service of department of internal medicine in Binjiang Hospital of Tianjin from 1994 to 1996. The cases were selected from 312 patients with hypert... | ['Age of Onset', 'Aged', 'Body Weight', 'Case-Control Studies', 'China', 'Family Health', 'Female', 'Humans', 'Hypertension', 'Male', 'Matched-Pair Analysis', 'Middle Aged', 'Obesity'] | 12,597,506 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.252.474.164'], ['N01.400.300'], ['B01.050.150.90... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pre-eclampsia is a risk factor of carotid artery atherosclerosis. | BACKGROUND: A history of pre-eclampsia has been shown to be associated with an increased risk of subsequent coronary artery disease. The intima-media thickness of carotid arteries and the detection of plaques are useful measures as regards preclinical atherosclerosis. The aim of this study was to examine whether women ... | ['Aged', 'Carotid Artery Diseases', 'Case-Control Studies', 'Cross-Sectional Studies', 'Disease Progression', 'Female', 'Finland', 'Health Surveys', 'Humans', 'Hypertension, Pregnancy-Induced', 'Logistic Models', 'Middle Aged', 'Pre-Eclampsia', 'Pregnancy', 'Risk Factors', 'Tunica Intima', 'Tunica Media', 'Ultrasonogra... | 19,407,443 | [['M01.060.116.100'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.550.291.656'], ['Z01.542.816.186'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Increased fat accumulation in the liver in HIV-infected patients with antiretroviral therapy-associated lipodystrophy. | OBJECTIVE: To determine liver fat content in patients with highly active antiretroviral therapy (HAART)-associated lipodystrophy.BACKGROUND: Lipodystrophy in several animal models is associated with fat accumulation in insulin-sensitive tissues, such as the liver. This causes hyperinsulinaemia, dyslipidaemia and other ... | ['Adipose Tissue', 'Adult', 'Antiretroviral Therapy, Highly Active', 'Cross-Sectional Studies', 'HIV Infections', 'HIV-Associated Lipodystrophy Syndrome', 'Humans', 'Liver', 'Male', 'Protons', 'Spectrum Analysis'] | 12,409,740 | [['A10.165.114'], ['M01.060.116'], ['E02.319.310.075'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.875.550', 'C01.221.812.640.400.530', 'C01.778.6... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Renal and systemic-hemodynamic response to isovolemic exchange transfusion with hemoglobin cross-linked with bis (3,5-dibromosalicyl) fumarate or albumin. | Experiments were done in anesthetized rats to determine systemic hemodynamic and renal functional effects of isovolemic exchange transfusion with either 5% albumin or hemoglobin cross-linked with bis (3,5-dibromosalicyl) fumarate (XLHb) in volumes ranging from 1 to 6.3 ml.100 gm-1. Hematocrit decreased in proportion to... | ['Animals', 'Aspirin', 'Blood Substitutes', 'Exchange Transfusion, Whole Blood', 'Glomerular Filtration Rate', 'Half-Life', 'Hemodynamics', 'Hemoglobins', 'Indomethacin', 'Kidney', 'Macromolecular Substances', 'Rats', 'Rats, Sprague-Dawley', 'Serum Albumin'] | 7,665,973 | [['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['D27.505.954.502.140', 'J01.637.087.249'], ['E02.095.135.469'], ['E01.370.390.400.300', 'G08.852.357'], ['G01.910.405'], ['G09.330.380'], ['D12.776.124.400', 'D12.776.422.316.762'], ['D03.633.100.473.420'], ['A05.810.453'], ['D05'], ['B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. | Clinicians are in need of better diagnostic markers for rapid diagnosis of severe infections. Therefore, we studied the diagnostic significance of mean cell volume of neutrophils (MNV) and monocytes (MMV) compared with Interleukin-6 (IL-6), C-reactive protein (CRP) and white blood cell count for predicting systemic cli... | ['Aged', 'Bacterial Infections', 'C-Reactive Protein', 'Erythrocyte Indices', 'Female', 'Humans', 'Interleukin-6', 'Lymphocyte Count', 'Male', 'Middle Aged', 'Monocytes', 'Neutrophils', 'Predictive Value of Tests', 'Sensitivity and Specificity', 'Sepsis'] | 19,919,621 | [['M01.060.116.100'], ['C01.150.252'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E01.370.225.625.230', 'E05.200.625.230', 'G09.188.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E01.370.225.500.195.107.5... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biochemical characterization of buffalo liver glucose-6-phosphate dehydrogenase isoforms. | Glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme involved in the pentose phosphate pathway. This works represents purification of two buffalo liver glucose-6-phosphate dehydrogenases (BLG6PD1 and BLG6PD2) using combination of ammonium sulfate precipitation and several chromatographic columns. Both en... | ['Animals', 'Buffaloes', 'Chlorides', 'Glucosephosphate Dehydrogenase', 'Hydrogen-Ion Concentration', 'Isoenzymes', 'Liver', 'NADP'] | 25,980,795 | [['B01.050'], ['B01.050.150.900.649.313.500.380.135'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D08.811.682.047.150.300'], ['G02.300'], ['D08.811.348', 'D12.776.800.300'], ['A03.620'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polycyclic aromatic hydrocarbon-DNA adducts in spontaneously aborted fetal tissue. | Fetal tissue and placentas from 15 human spontaneous abortions were evaluated for DNA adducts of polycyclic aromatic hydrocarbons (PAHs), using a competitive enzyme-linked immunosorbent assay (ELISA) with fluorescent end-point detection. PAH-derived adducts were found in 43% of placentas, 27% of fetal liver samples and... | ['Abortion, Spontaneous', 'Carcinogens', 'DNA', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Fetus', 'Gestational Age', 'Humans', 'Liver', 'Lung', 'Placenta', 'Polycyclic Compounds', 'Pregnancy'] | 2,401,055 | [['C13.703.039', 'G08.686.784.769.496.125'], ['D27.888.569.100'], ['D13.444.308'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], [... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antiproliferative activity of some unsubstituted angular analogoues of ellipticine. | With the aim of obtaining further knowledge on the antiproliferative activity of pyrroloquinolines and isoquinolines, we prepared four unsubstituted angular pyridotetrahydrocarbazoles having a fourth non-aromatic ring, via modified Fischer synthesis. These compounds may be considered as simpler analogues of ellipticine... | ['Animals', 'Antiviral Agents', 'CHO Cells', 'Carcinoma, Ehrlich Tumor', 'Cell Division', 'Circular Dichroism', 'Cricetinae', 'DNA', 'Ellipticines', 'Intercalating Agents', 'Mice', 'Myoviridae', 'Structure-Activity Relationship'] | 7,766,281 | [['B01.050'], ['D27.505.954.122.388'], ['A11.251.210.200', 'A11.436.155'], ['C04.557.470.200.200', 'C04.619.169'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.196.867.151'], ['B01.050.150.900.649.313.992.635.075.250'], ['D13.444.308'], ['D03.132.436.681.333', 'D03.633.100.473.144.249... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Papillary carcinoma with extensive squamous metaplasia arising from thyroglossal duct cyst in an 11-year-old girl: significance of differentiation from squamous cell carcinoma: a case report. | We report a case of papillary carcinoma (PC) with extensive squamous metaplasia arising from a thyroglossal duct cyst (TDC) that required differential diagnosis from squamous cell carcinoma (SCC). An 11-year-old Japanese girl presented with a 9-month history of an anterior-midline neck mass that was clinically diagnose... | ['Biopsy', 'Carcinoma, Papillary', 'Carcinoma, Squamous Cell', 'Cell Differentiation', 'Child', 'Diagnosis, Differential', 'Female', 'Humans', 'Metaplasia', 'Thyroglossal Cyst', 'Thyroid Gland', 'Thyroid Neoplasms', 'Thyroidectomy', 'Tomography, X-Ray Computed'] | 21,496,518 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.152'], ['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Associations between missing teeth with unmet needs and socioeconomic status among South Korean dentate government employees. | OBJECTIVE: This study aims to examine associations between missing teeth with unmet needs (MTUN) and socioeconomic status, represented by income and place of residence.METHODS: The National Health Insurance Corporation dataset of 822,325 dentate Korean government employees' dental examinations results, questionnaire re... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Chi-Square Distribution', 'Dental Prosthesis', 'Federal Government', 'Female', 'Health Services Needs and Demand', 'Humans', 'Income', 'Korea', 'Logistic Models', 'Male', 'Middle Aged', 'Rural Population', 'Smoking', 'Social Class', 'Tooth Loss', 'Toothbrushing'] | 17,899,904 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E06.780.346', 'E07.695.190'], ['I01.409.137', 'I01.409.418.625', 'N03.540.348.500', 'N03.540.400.750'], ['N03.349.380.420', 'N05... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Skeletal variations in children with Class II division 1 malocclusion]. | The aim of this investigation was to determine skeletal variations in patients with class II division 1. malocclusion. It was analyzed sagittal position of upper and lower jaws in relation to the cranial base. The sample consisted of 45 patients of both sexes, aged between 7 and 14 years. Antero-posterior position of m... | ['Adolescent', 'Cephalometry', 'Child', 'Female', 'Humans', 'Jaw', 'Male', 'Malocclusion, Angle Class II', 'Radiography'] | 2,206,405 | [['M01.060.057'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502', 'A14.521'], ['C07.793.494.630'], ['E01.370.350.700']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The impact of high non-starch polysaccharide intake on serum micronutrient concentrations in a cohort of women. | OBJECTIVE: Many public health campaigns encourage increased fibre consumption, but short-term studies suggest that various components of dietary fibre inhibit the absorption of certain micronutrients including carotenoids. These do not take into account long-term adaptation to nutrient intake levels. We aimed to invest... | ['Absorption', 'Adult', 'Aged', 'Carotenoids', 'Diet Records', 'Diet, Vegetarian', 'Dietary Fiber', 'Dietary Supplements', 'Female', 'Humans', 'Life Style', 'Linear Models', 'Micronutrients', 'Middle Aged', 'Polysaccharides', 'Prospective Studies', 'Smoking', 'Socioeconomic Factors', 'Starch', 'United Kingdom', "Women'... | 15,153,260 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['M01.060.116.100'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['N04.452.859.360'], ['E02.642.249.300', 'G07.203.650.240.300'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400']... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenome... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Influence of low oxygen concentration on derepression of nitrogenase in Klebsiella pneumoniae. | Effects of oxygen derepression of nitrogenase were studied in Klebsiella pneumoniae, using oxyleghaemoglobin to supply and monitor very low dissolved O2 concentrations in a steady-state system. Expression of the nifH gene was studied by using a nifH::lac fusion strain, which aslo carried the Nif+ plasmid pRD1 so that t... | ['Enzyme Repression', 'Genes', 'Genes, Bacterial', 'Klebsiella pneumoniae', 'Leghemoglobin', 'Nitrogenase', 'Oxygen', 'Plasmids'] | 7,050,298 | [['G05.308.320.300'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['D12.776.422.316.881', 'D12.776.765.500'], ['D08.811.682.647'], ['D01.268.185.550', 'D01.362.670'], ['G05.360.600']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibodies against Stachybotrys chartarum extract and its antigenic components, Stachyhemolysin and Stachyrase-A: a new clinical biomarker. | BACKGROUND: IgG and IgE antibodies against Stachybotrys extract have been reported in allergic patients and residents of water-damaged buildings. Detection of these antibodies in blood was partially attributed to cross-reacting proteins from other fungi. There is a need for a specific method to detect antibodies agains... | ['Antibodies, Fungal', 'Antigens, Fungal', 'Apoptosis', 'B-Lymphocytes', 'Biomarkers', 'Cell Line', 'Enzyme-Linked Immunosorbent Assay', 'Hemolysin Proteins', 'Humans', 'Hypersensitivity', 'Immunoglobulin E', 'Immunoglobulin G', 'Serine Endopeptidases', 'Stachybotrys'] | 15,874,884 | [['D12.776.124.486.485.114.179', 'D12.776.124.790.651.114.179', 'D12.776.377.715.548.114.179'], ['D23.050.202'], ['G04.146.954.035'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D23.101'], ['A11.251.210'], ['E05.478.566.350.170', 'E05.478.56... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic rectal bleeding in Proteus syndrome. | Proteus Syndrome is a rare congenital hamartomatous disorder that typically manifests itself in overgrowth, vascular malformation and disregulation of fatty tissue. The tissues affected are commonly the limbs but can be of any tissue. Vascular anomalies are common and appear at random sites on the body. Diagnosis is of... | ['Adolescent', 'Chronic Disease', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Proteus Syndrome', 'Rectum'] | 21,901,955 | [['M01.060.057'], ['C23.550.291.500'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.445.435.500', 'C04.651.435.500', 'C05.116.099.750', 'C05.660.585.620', 'C16.131.077.740', 'C16.131.621.585.620'], ['A03.556.124.526.767', 'A03.556.249.249.767']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
True grit: the tale of a subcutaneous mass in a dog. | A 14-month-old, intact, male German Shepherd dog was referred for a 6 x 3-cm, firm mass in the left pelvic limb. Fine needle aspiration yielded chalky white material. May-Gr?nwald-Giemsa-stained smears showed a uniform background of amorphous, poorly stained, light-blue material and scattered foamy macrophages, a few n... | ['Animals', 'Calcinosis', 'Dog Diseases', 'Dogs', 'Male'] | 15,732,024 | [['B01.050'], ['C18.452.174.130'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of gliclazide beyond metabolic control. | Evidence implicates hyperglycemia-derived oxygen free radicals as mediators of diabetic complications. Recent studies demonstrate that hyperglycemia-induced overproduction of superoxide seems the first and key event in the activation of all pathways involved in the pathogenesis of diabetic complications. Superoxide ove... | ['Antioxidants', 'DNA Damage', 'Diabetes Complications', 'Diabetes Mellitus, Type 2', 'Gliclazide', 'Humans', 'Hypoglycemic Agents', 'Islets of Langerhans', 'Lipid Peroxidation', 'Oxidative Stress'] | 16,631,804 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G05.200'], ['C19.246.099'], ['C18.452.394.750.149', 'C19.246.300'], ['D02.065.950.828.475', 'D02.886.590.795.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['A03.734.414', 'A06.300.414'], ['G02.111.515', 'G03.295.531.587'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NAD(P)H: quinone oxidoreductase (NQO1) gene polymorphism and schizophrenia. | NAD(P)H: quinone oxidoreductase (NQO1), an obligate two-electron reductase of quinones, prevents their participation in redox cycling and subsequent generation of reactive oxygen species (ROS). Reduced or negative activity of NQO1 would lead to an excess of neurotoxic compounds of cathecolamine o-quinones and ROS. Rece... | ['Adult', 'Cross-Sectional Studies', 'Female', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'NAD(P)H Dehydrogenase (Quinone)', 'Oxidation-Reduction', 'Polymorphism, Genetic', 'Schizophrenia'] | 12,834,817 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D08.811.682.608.800.500'], ['G02.700', 'G03.295.531'], ['G05.365.795'], ['F03.700.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-â1. | Enhanced biosynthesis of several cytokines, such as, transforming growth factor-â1 (TGF-â1), is detected in gestational diabetes mellitus (GDM). In this study, we addressed the question of whether the exposure to the abnormal milieu of GDM in vivo affects gene expression pattern of human umbilical vein endothelial cell... | ['Case-Control Studies', 'Cell Movement', 'Diabetes, Gestational', 'Female', 'Fetus', 'Gene Expression Profiling', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Phenotype', 'Pregnancy', 'Protein-Serine-Threonine Kinases', 'Receptor, Transforming Growth Factor-beta Type I', 'Receptors, Transforming Growth Factor ... | 25,819,880 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G04.198', 'G07.568.500.180'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['A16.378'], ['E05.393.332'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.695'], ['G08.686.784.769'], ['D08.811.913.696.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Propofol suppresses a hyperpolarization-activated inward current in rat hippocampal CA1 neurons. | We examined the effect of propofol and thiopental, intravenous anesthetics, on the hyperpolarization-activated inward current (I(H)), whose functional role on the neuronal activity has been evaluated. Whole-cell recordings of I(H) evoked by hyperpolarizing step pulses were taken from hippocampal CA1 neurons in rat brai... | ['Anesthetics, Intravenous', 'Animals', 'Cell Membrane', 'Dose-Response Relationship, Drug', 'Hippocampus', 'Ion Channels', 'Membrane Potentials', 'Neural Inhibition', 'Neurons', 'Organ Culture Techniques', 'Patch-Clamp Techniques', 'Pharmacokinetics', 'Propofol', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, GABA-A', 'T... | 11,578,823 | [['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['B01.050'], ['A11.284.149'], ['G07.690.773.875', 'G07.690.936.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term results with single pediatric donor kidney transplants in adult recipients. | PURPOSE: We investigated whether transplantation of single pediatric donor kidneys into adults leads to an increased incidence of functional allograft impairment and complications, as previously reported.MATERIALS AND METHODS: To evaluate long-term functional outcome using single pediatric donor kidneys 60 adults (stud... | ['Adult', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Graft Survival', 'Humans', 'Incidence', 'Infant', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prognosis', 'Survival Rate', 'Time Factors', 'Tissue Donors'] | 8,709,356 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes in extracellular levels of amygdala amino acids in genetically fast and slow kindling rat strains. | A neurochemical basis for many of the epilepsies has long been suspected to result from an imbalance between excitatory and inhibitory neurotransmitter mechanisms. Data supporting changes in extrasynaptic amino acid levels during epileptogenesis, however, remain controversial. In the present study, we used in vivo micr... | ['Amino Acids', 'Amygdala', 'Animals', 'Differential Threshold', 'Electrophysiology', 'Extracellular Space', 'Genetic Predisposition to Disease', 'Glutamic Acid', 'Hippocampus', 'Kindling, Neurologic', 'Male', 'Rats', 'Rats, Inbred Strains', 'Seizures', 'Time Factors', 'gamma-Aminobutyric Acid'] | 12,133,592 | [['D12.125'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['F02.463.593.710.370'], ['H01.158.344.528', 'H01.158.782.236'], ['A10.082.500', 'A11.284.295'], ['C23.550.291.687.500', 'G05.380.355'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['A08.186.211.180.405', 'A08.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Alterations of cell cycle regulators are less frequent in advanced non-small cell lung cancer than in resectable tumours. | Prognosis of lung cancer is related to stage of disease at time of diagnosis. In this study we examine alterations of pathways governing the cell cycle, in particular pRb-cyclinD1-p16 alpha and p53-p14ARF, in a series of NSCLC (n=92) at different stages at diagnosis. Using immunohistochemistry, we assessed the expressi... | ['Aged', 'Carcinoma, Non-Small-Cell Lung', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Nucleus', 'Cyclin D1', 'Cyclin-Dependent Kinase Inhibitor p16', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclins', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis... | 11,551,418 | [['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G04.144'], ['D12.776.167'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.644.360.225.2... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Femtosecond optical ranging of corneal incision depth. | Excimer laser ablation has been proposed as a technique for keratorefractive surgery. Clinical acceptance of linear-incision laser keratectomy may depend on the availability of a method for accurately and noninvasively monitoring incision depth during the ablation process. We have developed a femto-second optical rangi... | ['Animals', 'Cattle', 'Cornea', 'Laser Therapy', 'Microscopy, Electron, Scanning', 'Optics and Photonics', 'Time Factors'] | 2,912,917 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A09.371.060.217'], ['E02.594', 'E04.014.520'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['H01.671.617', 'J01.293.688'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Effects of sialoadenectomy and parotin hormone on the development of rat sponge-induced granulation tissue. | A study was made concerning the effects of sialoadenectomy and parotin hormone administration upon sponge-induced granulation tissue of young adult rats. The effects of sialoadenectomy alone and sialoadenectomy plus a single subcutaneous injection of parotin hormone, in two different doses (0.15 and 0.30 mg), on the de... | ['Animals', 'Granulation Tissue', 'Hormones', 'Injections, Subcutaneous', 'Male', 'Rats', 'Salivary Glands', 'Salivary Proteins and Peptides'] | 961,337 | [['B01.050'], ['A10.165.450'], ['D06.472', 'D27.505.696.399.472'], ['E02.319.267.530.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['A03.556.500.760', 'A10.336.779', 'A14.549.760'], ['D12.644.848', 'D12.776.850']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aneurysm of left ventricle and left coronary artery after non-penetrating chest trauma. | A 17 year old boy who sustained blunt chest trauma to his chest developed a proximal left anterior descending coronary artery aneurysm and an aneurysm of the left ventricle. He underwent left ventricular aneurysmectomy and was discharged to outpatient follow up. | ['Adolescent', 'Aneurysm', 'Coronary Disease', 'Coronary Vessels', 'Heart Aneurysm', 'Heart Injuries', 'Humans', 'Male', 'Wounds, Nonpenetrating'] | 6,639,821 | [['M01.060.057'], ['C14.907.055'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.015.114.269', 'A07.015.908.194'], ['C14.280.358', 'C14.907.055.608'], ['C26.891.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.974']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Homogeneous solid dispersion (HSD) system for rapid and stable production of succinic acid from lignocellulosic hydrolysate. | Continuous bio-production of succinic acid was reported in homogeneous solid dispersion (HSD) system utilizing porous coconut shell activated carbon (CSAC) as immobilization carrier. The aim of the present work was to implement the HSD system to increase the area of cell immobilization and the rate of succinic-acid pro... | ['Actinobacillus', 'Biotechnology', 'Carbon', 'Cellulose', 'Cocos', 'Fermentation', 'Glucose', 'Hydrolysis', 'Lignin', 'Porosity', 'Succinic Acid'] | 30,259,181 | [['B03.440.450.009', 'B03.660.250.550.050'], ['H01.158.550', 'J01.897.120'], ['D01.268.150'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['B01.650.940.800.575.912.250.093.211'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['G02.380'], ['D05.750.078.562.180... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Update on current care guidelines: urinary incontinence (female)]. | Female urinary incontinence (UI) is divided into stress (SUI), urgency (UUI), mixed (MUI) and overflow incontinence (chronic retention). Advanced age, obesity and pregnancy are the most important risk factors. Standardised questionnaires are used in diagnosis. The pad test, cough stress test and bladder diary are objec... | ['Age Factors', 'Cholinergic Antagonists', 'Cystoscopy', 'Female', 'Humans', 'Obesity', 'Palpation', 'Practice Guidelines as Topic', 'Pregnancy', 'Pregnancy Complications', 'Risk Factors', 'Suburethral Slings', 'Surveys and Questionnaires', 'Urinary Incontinence', 'Urodynamics'] | 22,506,323 | [['N05.715.350.075', 'N06.850.490.250'], ['D27.505.519.625.120.200', 'D27.505.696.577.120.200'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.1... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
ANKRD18A as a novel epigenetic regulation gene in lung cancer. | Lung cancer is one of the most common causes of cancer-related mortality worldwide. Effective early diagnosis and targeted therapies for lung cancer to reduce incidence and mortality would benefit from a better understanding of the key molecular changes that occur from normal to malignant tumor cells during lung cancer... | ['Ankyrin Repeat', 'Azacitidine', 'DNA Methylation', 'DNA Modification Methylases', 'Decitabine', 'Down-Regulation', 'Epigenesis, Genetic', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Promoter Regions, Genetic'] | 23,131,552 | [['G02.111.570.060.720.030', 'G02.111.570.820.709.275.500.030', 'G02.111.570.820.709.275.750.500.080', 'G02.111.570.820.709.275.875.030'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D08.811.150.240', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypertrophic obstructive cardiomyopathy and mitral regurgitation in Libman-Sacks endocarditis. | Hypertrophic obstructive cardiomyopathy in Libman-Sacks endocarditis is quite rare and the correct etiological relationship between them is unknown. Some changes may cause a secondary disorganization of the ordinary muscle structure, making a disarray pattern with irregular interwoven myocyte fibers. This case report d... | ['Cardiomyopathy, Hypertrophic', 'Coronary Artery Bypass', 'Echocardiography', 'Endocarditis', 'Female', 'Heart Valve Prosthesis', 'Humans', 'Lupus Erythematosus, Systemic', 'Middle Aged', 'Mitral Valve', 'Mitral Valve Insufficiency'] | 30,519,962 | [['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.282'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['M01.060.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Time series analysis of use patterns for common invasive technologies in critically ill patients. | PURPOSE: Critically ill patients are frequently managed with invasive technologies as part of their medical care. Little is known about use patterns. We examined use trends for invasive technologies used in critically ill patients.MATERIALS AND METHODS: Using time series analysis and data on 26 989 patients from 3 medi... | ['APACHE', 'Adult', 'Aged', 'Catheterization, Central Venous', 'Catheterization, Peripheral', 'Catheterization, Swan-Ganz', 'Critical Care', 'Critical Illness', 'Female', 'Humans', 'Intensive Care Units', 'Intubation, Intratracheal', 'Male', 'Middle Aged', 'Prospective Studies'] | 19,327,306 | [['E05.318.308.980.438.475.365', 'E05.318.308.980.438.475.456.500.250', 'N05.715.360.300.800.438.375.364.500.250', 'N06.850.520.308.980.438.475.364.500.250'], ['M01.060.116'], ['M01.060.116.100'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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