Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Loss to specialist follow-up in congenital heart disease; out of sight, out of mind. | OBJECTIVE: To evaluate the scale and clinical importance of loss to follow-up of past patients with serious congenital heart disease, using a common malformation as an example. To better understand the antecedents of loss to specialist follow-up and patients' attitudes to returning.DESIGN: Cohort study using NHS number... | ['Adolescent', 'Adult', 'Attitude of Health Personnel', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Continuity of Patient Care', 'Female', 'Follow-Up Studies', 'Health Behavior', 'Health Knowledge, Attitudes, Practice', 'Heart Valve Prosthesis Implantation', 'Humans', 'Infant', 'London', 'Lost to Follo... | 23,257,171 | [['M01.060.057'], ['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.145.488'], ['F01.100.150.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mcm10 mediates the interaction between DNA replication and silencing machineries. | The connection between DNA replication and heterochromatic silencing in yeast has been a topic of investigation for >20 years. While early studies showed that silencing requires passage through S phase and implicated several DNA replication factors in silencing, later works showed that silent chromatin could form witho... | ['Cell Cycle Proteins', 'Chromatin Immunoprecipitation', 'Chromosomal Proteins, Non-Histone', 'DNA Replication', 'G2 Phase', 'Gene Silencing', 'Genes, Fungal', 'Heterochromatin', 'Histone Deacetylases', 'Minichromosome Maintenance Complex Component 3', 'Minichromosome Maintenance Proteins', 'Models, Genetic', 'Mutation... | 19,064,704 | [['D12.776.167'], ['E05.393.170', 'E05.478.605.160'], ['D12.776.660.235', 'D12.776.664.235'], ['G02.111.225', 'G05.226'], ['G04.144.500.340'], ['G05.308.203.374'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['A11.284.430.106.279.345.190.160.180.383', 'D12.776.664.224.466', 'G... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Devic's optic neuromyelitis: analysis of 7 cases]. | INTRODUCTION: Devic's optic neuromyelitis is an unusual condition characterized by the association of unilateral or bilateral optic neuritis and myelitis, both of which are relapsing. Prognosis is usually poor, both for the optic nerve and for the spinal medulla which becomes cavitated. This leads to severe handicap an... | ['Adolescent', 'Adult', 'Cervical Vertebrae', 'Child', 'Diagnosis, Differential', 'Disease Progression', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Medulla Oblongata', 'Neuromyelitis Optica', 'Prognosis', 'Quality of Life', 'Retrospective Studies', 'Severity of Illness Index'] | 10,229,960 | [['M01.060.057'], ['M01.060.116'], ['A02.835.232.834.151'], ['M01.060.406'], ['E01.171'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.186.211.132.810.591.500'], ['C10.114.375.600.500', 'C10.114.375.800', 'C10.292.700.550.500', 'C10.314.350.600.500', 'C10.314.350.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sustained and focused attention deficits in adult ADHD. | OBJECTIVE: To examine the specificity of deficits in focused attention and sustained attention in adults with ADHD and to evaluate the effect of comorbidity.METHOD: Twenty-eight adults with ADHD without comorbidity were compared with 28 ADHD outpatients with comorbidity. Two control groups were used: 68 adults referred... | ['Adult', 'Attention', 'Attention Deficit Disorder with Hyperactivity', 'Central Nervous System Stimulants', 'Cognition Disorders', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Reaction Time', 'Severity of Illness Index'] | 17,712,171 | [['M01.060.116'], ['F02.830.104.214'], ['F03.625.094.150'], ['D27.505.696.282', 'D27.505.954.427.220'], ['F03.615.250'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The heart team of cardiovascular care. | The management of complex cardiovascular disease has changed markedly with the development of new strategies of care, an increasing amount of scientific evidence-based data and appropriate use criteria. Applying this plethora of information and synthesizing it for presentation and recommendations to the patient and fam... | ['Aortic Valve', 'Cardiac Catheterization', 'Cardiovascular Diseases', 'Evidence-Based Medicine', 'Heart Diseases', 'Humans', 'Patient Care Team', 'Patient-Centered Care', 'Percutaneous Coronary Intervention'] | 23,449,424 | [['A07.541.510.110'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['C14'], ['H02.249.750', 'H02.403.200.400'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.715'], ['N04.590.233.727.407'], ['E04.100.814.529.968', 'E04.502.382.968']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A two-step strategy for enlargement of left arterial branch in a living related liver graft with dual arterial supply. | The use of small caliber arteries is probably responsible for the higher hepatic artery thrombosis rate initially reported after living related liver transplantation. We described a two-step strategy generating flow-induced enlargement of a small diameter artery in case of left graft dual arterial supply. The smaller a... | ['Adult', 'Child, Preschool', 'Family', 'Female', 'Follow-Up Studies', 'Graft Survival', 'Hepatectomy', 'Hepatic Artery', 'Humans', 'Laparoscopy', 'Liver', 'Liver Transplantation', 'Living Donors', 'Male', 'Nuclear Family', 'Time Factors', 'Tissue and Organ Harvesting'] | 11,923,706 | [['M01.060.116'], ['M01.060.406.448'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.340'], ['E04.210.556'], ['A07.015.114.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The prognostic value of microvascular invasion in early-intermediate stage hepatocelluar carcinoma: a propensity score matching analysis. | BACKGROUND: Microvascular invasion (MVI) is well established as a negative prognostic factor for hepatocelluar carcinoma (HCC). However, its prognostic value in different subgroups of Barcelona Clinical Liver Cancer (BCLC) stages remains to be elucidated.METHODS: Four hundred fifty-eight MVI-negative and 204 MVI-positi... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Disease-Free Survival', 'Female', 'Hepatectomy', 'Humans', 'Kaplan-Meier Estimate', 'Liver Neoplasms', 'Lymphocytes', 'Male', 'Microvessels', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Neutrophils', 'Predictive Value of Test... | 29,530,006 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E04.210.556'], ['B01.050.150.900.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Critical appraisal of apparently evidence-based written advertising in Pakistan. | OBJECTIVES: The objective of the study was to critically assess references cited in support of claims in drug advertisements.METHODS: Drug advertising brochures were collected from privately practicing General Practitioners from different parts of Karachi. Three blinded reviewers then categorized each reference in the ... | ['Advertising', 'Documentation', 'Evidence-Based Medicine', 'Family Practice', 'Humans', 'Pakistan', 'Pamphlets', 'Patient Education as Topic'] | 17,932,785 | [['J01.219.687.274', 'L01.143.050'], ['L01.453.245'], ['H02.249.750', 'H02.403.200.400'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.723'], ['L01.178.682.707'], ['I02.233.332.500', 'N02.421.726.407.680']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Measures of obesity and cardiovascular risk among men and women. | OBJECTIVES: This study examined associations between anthropometric measures (body mass index, waist circumference, waist-to-hip ratio, waist-to-height ratio [WHtR]) and risk of incident cardiovascular disease (CVD) (including nonfatal myocardial infarction, nonfatal ischemic stroke, and cardiovascular death).BACKGROUN... | ['Body Mass Index', 'Cardiovascular Diseases', 'Cohort Studies', 'Confounding Factors, Epidemiologic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Myocardial Infarction', 'Myocardial Ischemia', 'Obesity', 'Proportional Hazards Models', 'Risk Assessment', 'Waist-Hip Ratio'] | 18,702,962 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.240', 'N06.850.490.718'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
neuroVIISAS: approaching multiscale simulation of the rat connectome. | neuroVIISAS is a generic platform which allows the integration of neuroontologies, mapping functions for brain atlas development, and connectivity data administration; all of which are required for the analysis of structurally and neurobiologically realistic simulations of networks. What makes neuroVIISAS unique is the... | ['Animals', 'Brain', 'Brain Mapping', 'Computer Simulation', 'Models, Neurological', 'Neural Pathways', 'Rats'] | 22,350,719 | [['B01.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['L01.224.160'], ['E05.599.395.642'], ['A08.612'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Short fibre-reinforced composite for extensive direct restorations: a laboratory and computational assessment. | OBJECTIVES: The objective of the study was to evaluate the effectiveness of a short fibre-reinforced composite (FRC) applied in combination with a conventional filler composite (CFC) on the fatigue resistance, fracture strength, failure mode and stress distribution, for restorations of premolars under two loading angle... | ['Bicuspid', 'Composite Resins', 'Dental Caries', 'Dental Restoration Failure', 'Dental Restoration, Permanent', 'Dental Stress Analysis', 'Dentin-Bonding Agents', 'Finite Element Analysis', 'Humans', 'In Vitro Techniques', 'Materials Testing', 'Surface Properties'] | 26,374,748 | [['A14.549.167.860.150'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['C07.793.720.210'], ['E06.323.400', 'E06.780.346.725'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['E06.308'], ['D25.339.291.300', 'J01.637.051.339.291.300... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effects of Mycoplasma anatis and cold stress on hatching success and growth of mallard ducklings. | We inoculated game-farm mallard (Anas platyrhynchos) eggs and 1-day-old birds with Mycoplasma anatis to determine its effect on hatching success and growth rates of ducklings. Inoculations of eggs reduced hatching success, hatchling size, and duckling growth rates, compared to controls. Intratracheal inoculations of 1-... | ['Animals', 'Bird Diseases', 'Cold Temperature', 'Ducks', 'Eggs', 'Female', 'Infectious Disease Transmission, Vertical', 'Male', 'Mycoplasma', 'Mycoplasma Infections', 'Sex Characteristics', 'Stress, Physiological'] | 8,583,634 | [['B01.050'], ['C22.131'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['G07.203.300.470', 'J02.500.470'], ['N06.850.335.875'], ['B03.440.860.580.553.553'], ['C01.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The group II chaperonin Mm-Cpn binds and refolds human ãD crystallin. | Chaperonins assist in the folding of nascent and misfolded proteins, though the mechanism of folding within the lumen of the chaperonin remains poorly understood. The archeal chaperonin from Methanococcus marapaludis, Mm-Cpn, shares the eightfold double barrel structure with other group II chaperonins, including the eu... | ['Adenosine Triphosphate', 'Bacterial Proteins', 'Group II Chaperonins', 'Humans', 'Methanococcus', 'Protein Binding', 'Protein Refolding', 'gamma-Crystallins'] | 20,981,710 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.776.097'], ['D08.811.277.040.025.142.750', 'D12.776.580.216.210.795'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B02.200.538.525.500'], ['G02.111.679', 'G03.808'], ['G01.154.651.501', 'G02.111.688.501'], ['D12.776.306.366.850... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of PET or PET/CT in the post-therapy surveillance of uterine sarcoma. | OBJECTIVE: To evaluate the clinical accuracy and clinical impact of positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) in detecting and treating tumor recurrence in patients with treated uterine sarcoma.METHODS: Results of 36 patients who underwent PET or PET/CT in post-ther... | ['Adult', 'Cohort Studies', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Population Surveillance', 'Positron-Emission Tomography', 'Reproducibility of Results', 'Retrospective Studies', 'Sarcoma', 'Tomography, X-Ray Computed', 'Uterine Neoplasms'] | 18,308,380 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675'], ['E01.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Performance of low-dose cosyntropin stimulation test handled via plastic tube. | PURPOSE: Studies on 1 ìg low-dose test showed that among 1 ìg cosyntropin samples pushed through long IV plastic tubing, some adrenocorticotropic hormone dosage was not recovered, and in healthy volunteers it provided subnormal cortisol responses. The aim of the current study is to assess whether there is any loss in a... | ['Adrenal Insufficiency', 'Adrenocorticotropic Hormone', 'Adult', 'Cosyntropin', 'Diagnostic Tests, Routine', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Saliva', 'Sensitivity and Specificity', 'Young Adult'] | 28,530,018 | [['C19.053.500'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['D06.472.699.327.935.531.500.200', 'D06.472.699.631.525.600.531.500.200', 'D12.644.4... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of health risks from exposure to arsenic and heavy metals through consumption of ten fish species. | In this study, the levels of 11 heavy metal(loid)s (HMs) were determined in ten different fish species (wild, farmed, freshwater, and marine) frequently consumed in Turkey and compared with the maximum permissible limits (MPLs) established by international standards. Also, human health risks for the consumers were asse... | ['Animals', 'Arsenic', 'Carps', 'Dietary Exposure', 'Environmental Monitoring', 'Food Contamination', 'Fresh Water', 'Humans', 'Metals, Heavy', 'Oncorhynchus mykiss', 'Risk Assessment', 'Seafood', 'Turkey', 'Water Pollutants, Chemical'] | 31,520,375 | [['B01.050'], ['D01.268.513.249'], ['B01.050.150.900.493.200.244.248'], ['N06.850.460.350.040'], ['N06.850.460.350.080', 'N06.850.780.375'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['G16.500.275.280', 'N06.230.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Wavelength- and time-dependence of potentiometric non-linear optical signals from styryl dyes. | Second harmonic generation (SHG) imaging microscopy is an important emerging technique for biological research, complementing existing one- and two-photon fluorescence (2PF) methods. A non-linear phenomenon employing light from mode-locked Ti:sapphire or fiber-based lasers, SHG results in intrinsic optical sectioning w... | ['Fiber Optic Technology', 'Fluorescent Dyes', 'Lasers', 'Microscopy, Fluorescence, Multiphoton', 'Patch-Clamp Techniques', 'Potentiometry', 'Sensitivity and Specificity'] | 16,645,740 | [['H01.671.617.249'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E07.632.490', 'E07.710.520'], ['E01.370.350.515.458.500', 'E01.370.350.515.717.250', 'E05.595.458.500', 'E05.595.717.250'], ['E05.200.500.905', 'E05.242.800'], ['E05.196.922.750', 'E05.301.710'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N... | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Post-transcriptional regulation of gene expression in eukaryotes: effect of stressors on mRNA stability in vitro]. | The effect of field drought on gene expression in developing Zea mays L. grain and the influence of the imbalance of essential amino acids on the expression of genes in white-rat liver at the mRNA stability level were studied. A special ommp system, which included incubation (65 degrees C, 5 min) of an aqueous preparat... | ['Animals', 'Lysine', 'Models, Genetic', 'RNA Processing, Post-Transcriptional', 'RNA, Messenger', 'Rats', 'Stress, Physiological', 'Triticum', 'Tryptophan', 'Zea mays'] | 9,879,009 | [['B01.050'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['E05.599.395.397'], ['G02.111.760', 'G03.839', 'G05.308.700'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['G07.775'], ['B01.650.940.800.575.912.250.822.918'], ['D12.125.072.050.850', 'D12.125.142.875'], ['B01.650.940.800.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of three-dimensional speckle tracking echocardiography to left ventricular rotation and twist in patients with silent myocardial ischemia]. | OBJECTIVE: To analyze the characteristics of left ventricular rotation and twist in patients with silent myocardial ischemia (SMI) by three-dimensional speckle tracking echocardiography (3D-STE), and to explore the diagnostic value of this method for SMI.
METHODS: According to Gensini score, 66 patients with SMI were d... | ['Coronary Artery Disease', 'Echocardiography, Three-Dimensional', 'Heart Ventricles', 'Humans', 'Myocardial Ischemia', 'Rotation', 'Ventricular Function, Left'] | 27,592,580 | [['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.350.130.750.230', 'E01.370.350.400.200', 'E01.370.350.850.220.230', 'E01.370.370.380.220.230'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647', 'C14.907.585'], ['G01.482.703'], ['G09.330.955.800']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attenuated phrenic long-term facilitation in orexin neuron-ablated mice. | We examined phrenic long-term facilitation (LTF) in urethane-anesthetized, vagotomized, paralyzed, and artificially ventilated orexin neuron-ablated mice and their wild-type littermates. Effect of isocapnic single hypoxic episode (SHE, for 45 s) and intermittent hypoxia (IH, 5 times of SHE separated by 5 min) on phreni... | ['Action Potentials', 'Animals', 'Hypoxia', 'Intracellular Signaling Peptides and Proteins', 'Long-Term Potentiation', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Neuropeptides', 'Orexins', 'Phrenic Nerve', 'Respiratory Mechanics', 'Time Factors', 'Vagotomy'] | 19,664,728 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['C23.888.852.079'], ['D12.644.360', 'D12.776.476'], ['G11.561.638.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500', 'B01.050.150.900.649.313... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency. | Breast milk normally contains adequate zinc to meet infant requirements up to six months of age; however, transient neonatal zinc deficiency has been documented in exclusively breastfed infants of women with low milk zinc concentration. This condition is not corrected by maternal zinc supplementation, supporting the sp... | ['Amino Acid Sequence', 'Animals', 'Cation Transport Proteins', 'Dietary Supplements', 'Female', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Infant', 'Infant, Newborn', 'Mammary Glands, Animal', 'Mice', 'Milk, Human', 'Molecular Sequence Data', 'Mutation', 'Sequence Homology, Amino Acid', 'Zinc'] | 17,065,149 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['G07.203.300.456', 'J02.500.456'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['B01.050.150... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Passive drainage versus primary closure after total ear canal ablation-lateral bulla osteotomy in dogs: 59 dogs (1985-1995). | OBJECTIVE: Compare passive wound drainage to primary closure of total ear canal ablation-lateral bulla osteotomy (TECA-LBO) in dogs.STUDY DESIGN: Retrospective analysis of medical records.SAMPLE POPULATION: Fifty-nine dogs with end-stage otitis externa or neoplasia of the external and middle ear.METHODS: Medical record... | ['Animals', 'Dog Diseases', 'Dogs', 'Drainage', 'Ear Canal', 'Ear Neoplasms', 'Female', 'Incidence', 'Male', 'Osteotomy', 'Otitis Externa', 'Postoperative Complications', 'Retrospective Studies', 'Wound Healing'] | 9,150,559 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.309', 'E04.237'], ['A09.246.272.396'], ['C04.588.443.665.312', 'C09.218.334', 'C09.647.312'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E04.555.580'], ['C09.218.705.496... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cardiovascular responsiveness to vasoactive agents in rats with obstructive jaundice. | 1. Pressor responses to tyramine, beta-phenylethylamine and angiotensin II were normal in urethane-anaesthetized rats 7 days after division of the common bile duct. The pressor response to noradrenaline was enhanced at the highest dose level used. 2. The hypotensive response to haemorrhage was exaggerated in bile duct ... | ['Anesthesia', 'Angiotensin II', 'Animals', 'Blood Pressure', 'Cholestasis', 'Hemodynamics', 'Hemorrhage', 'Male', 'Norepinephrine', 'Phenethylamines', 'Rats', 'Tyramine', 'Vasoconstrictor Agents'] | 7,166,008 | [['E03.155'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C06.130.120.135'], ['G09.330.380'], ['C23.550.414'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.09... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impedance measures for a better understanding of the electrical stimulation of the inner ear. | The performance of cochlear implant (CI) listeners is limited by several factors among which the lack of spatial selectivity of the electrical stimulation. Recently, many studies have explored the use of multipolar strategies where several electrodes are stimulated simultaneously to focus the electrical field in a rest... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cochlear Implants', 'Deafness', 'Ear, Inner', 'Electric Impedance', 'Electric Stimulation', 'Electric Stimulation Therapy', 'Electrodes, Implanted', 'Female', 'Humans', 'Male', 'Middle Aged'] | 30,523,898 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['A09.246.300'], ['G01.358.500.249.277.350'], ['E05.723.402'], ['E02.331', 'E02... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Unzipping single DNA molecules to study nucleosome structure and dynamics. | DNA unzipping is a powerful tool to study protein-DNA interactions at the single-molecule level. In this chapter, we provide a detailed and practical guide to performing this technique with an optical trap, using nucleosome studies as an example. We detail protocols for preparing an unzipping template, constructing and... | ['Base Sequence', 'Chromatin Assembly and Disassembly', 'Chromosomal Proteins, Non-Histone', 'DNA', 'Histones', 'Nucleic Acid Conformation', 'Nucleic Acid Denaturation', 'Nucleosomes', 'Optical Tweezers', 'Plasmids', 'Polymerase Chain Reaction', 'Protein Binding', 'Protein Interaction Mapping', 'Sensitivity and Specifi... | 22,929,764 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.400.095', 'G05.213.095', 'G05.308.095'], ['D12.776.660.235', 'D12.776.664.235'], ['D13.444.308'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['G02.111.570.820.486', 'G05.360.580'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['A11.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Prevalence of bacterial prostatitis in benign prostatic hyperplasia. | To define the prevalence of bacterial prostatitis and urinary tract infection (U.T.I) among benign prostatic hyperplasia patients (B.H.P) undergoing prostatectomy trans urethral resection of prostate (T.U.R.P.), 100 consecutive patient has their preoperative and post-operative urine cultures along with tissue culture o... | ['Anti-Bacterial Agents', 'Bacterial Infections', 'Gentamicins', 'Humans', 'Male', 'Prostatic Hyperplasia', 'Prostatitis', 'Urinary Tract Infections'] | 9,401,238 | [['D27.505.954.122.085'], ['C01.150.252'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.565.500'], ['C12.294.565.750'], ['C01.915', 'C12.777.892', 'C13.351.968.892']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensory eye balance in surgically corrected intermittent exotropes with normal stereopsis. | Surgery to align a deviated or strabismic eye is often done for both functional as well as cosmetic reasons. Although amblyopia is often an impediment to regaining full binocularity in strabismics in general, intermittent exotropes, because their deviation is intermittent, have no amblyopia and some degree of stereopsi... | ['Adolescent', 'Adult', 'Depth Perception', 'Exotropia', 'Female', 'Humans', 'Male', 'Sensation', 'Vision, Binocular'] | 26,287,935 | [['M01.060.057'], ['M01.060.116'], ['F02.463.593.200', 'F02.463.593.778.255'], ['C10.292.562.887.650', 'C11.590.810.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816', 'G11.561.790'], ['F02.463.593.932.885']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A note on amounts of [14C] in laying hens' blood after intramuscular administration of [4-14C]-estrone. | [4-14C]-Estrone in 2 ml. ethylene glycol was injected into the breast muscles of S.C. White Leghorn laying hens and the amounts of plasma [14C] per ml. whole blood were measured at various times thereafter. Maximal values were observed at 30 to 50 minutes after injection. The values then declined logarithmically with t... | ['Animals', 'Chickens', 'Estrone', 'Female', 'Injections, Intramuscular'] | 935,015 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.040.502.497', 'D06.472.334.851.437.996'], ['E02.319.267.530.460']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of anterolateral and posterior approaches in the management of thoracolumbar burst fractures. | OBJECT: The authors undertook a retrospective cohort study of patients with T11-L2 thoracolumbar burst fractures who underwent decompression and the placement of instrumentation via the anterolateral or posterior approach.METHODS: There were 63 thoracolumbar burst fractures in 45 male and 18 female patients. The instru... | ['Adult', 'Female', 'Follow-Up Studies', 'Health Care Costs', 'Humans', 'Length of Stay', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Retrospective Studies', 'Spinal Fractures', 'Spinal Fusion', 'Thoracic Vertebrae'] | 16,925,077 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C23.550.767'], ['E01.370.350.700']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relation of Gothic arch apex to dentist-assisted centric relation. | These data suggest that the widely held belief that thumb pressure can position the mandible consistently more posterior than the position indicated by the Gothic arch apex is unfounded. Furthermore, this study provides no evidence to support the contention that the dentist-assisted jaw relation is more reproducible th... | ['Adult', 'Cephalometry', 'Dental Occlusion', 'Dental Occlusion, Centric', 'Humans', 'Jaw Relation Record', 'Mandible', 'Movement', 'Pressure'] | 6,929,927 | [['M01.060.116'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['E06.276', 'G10.549.208'], ['E06.276.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.520'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['G07.568', 'G11.427.410'], ['G01.374.715']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation on treatment of sustained low-efficiency hemodialysis against patients with multiple organ dysfunction syndrome following wasp stings. | BACKGROUND: To evaluate the treatment of sustained low-efficiency hemodialysis (SLED) against patients with multiple organ dysfunction syndrome (MODS) following wasp stings.METHODS: Clinical data of 35 patients with MODS following wasp stings were retrospectively analysed. These patients were divided into three groups ... | ['Adult', 'Animals', 'Continuous Renal Replacement Therapy', 'Female', 'Humans', 'Insect Bites and Stings', 'Male', 'Middle Aged', 'Multiple Organ Failure', 'Renal Dialysis', 'Retrospective Studies', 'Treatment Outcome', 'Wasps'] | 31,269,901 | [['M01.060.116'], ['B01.050'], ['E02.870.150', 'E04.292.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.723.127.071', 'C26.176.143'], ['M01.060.116.630'], ['C23.550.835.525'], ['E02.870.300', 'E02.912.800'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dietary Zinc Oxide Modulates Antioxidant Capacity, Small Intestine Development, and Jejunal Gene Expression in Weaned Piglets. | The current study was conducted to investigate the effects of dietary zinc oxide (ZnO) on the antioxidant capacity, small intestine development, and jejunal gene expression in weaned piglets. Ninety-six 21-day-old piglets were randomly assigned to three dietary treatments. Each treatment had eight replicates with four ... | ['Animals', 'Antioxidants', 'Dietary Supplements', 'Gene Expression Regulation', 'Jejunum', 'Swine', 'Zinc Oxide'] | 27,339,255 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.300.456', 'J02.500.456'], ['G05.308'], ['A03.556.124.684.500', 'A03.556.249.750'], ['B01.050.150.900.649.313.500.880'], ['D01.650.550.975', 'D01.975.975']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Neutrophil functions in acne conglobata. | Chemotaxis, random migration, phagocytosis, spontaneous and stimulated NBT reduction were evaluated in neutrophils from the peripheral blood of 8 patients with acne conglobata and were found to be normal. Only 2 patients had an increased spontaneous NBT reduction, and another exhibited a defect in neutrophil adhesivene... | ['Acne Vulgaris', 'Adolescent', 'Adult', 'Chemotaxis, Leukocyte', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Neutrophils', 'Nitroblue Tetrazolium', 'Phagocytosis'] | 157,891 | [['C17.800.030.150', 'C17.800.794.111'], ['M01.060.057'], ['M01.060.116'], ['G04.198.424.233'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D03.383.129.617.700.500'... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. | SUMMARY: ChemBioServer is a publicly available web application for effectively mining and filtering chemical compounds used in drug discovery. It provides researchers with the ability to (i) browse and visualize compounds along with their properties, (ii) filter chemical compounds for a variety of properties such as st... | ['Algorithms', 'Cluster Analysis', 'Computer Simulation', 'Drug Discovery', 'Internet', 'Software'] | 22,962,344 | [['G17.035', 'L01.224.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.160'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['L01.224.230.110.500'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Chitosan scaffolds containing calcium phosphate salts and rhBMP-2: in vitro and in vivo testing for bone tissue regeneration. | Numerous strategies that are currently used to regenerate bone depend on employing biocompatible materials exhibiting a scaffold structure. These scaffolds can be manufactured containing particular active compounds, such as hydroxyapatite precursors and/or different growth factors to enhance bone regeneration process. ... | ['Animals', 'Bone Morphogenetic Protein 2', 'Bone Regeneration', 'Bone and Bones', 'Calcium Phosphates', 'Cell Line', 'Cell Proliferation', 'Cell Survival', 'Chitosan', 'Elastic Modulus', 'Humans', 'Kinetics', 'Male', 'Materials Testing', 'Mice', 'Rabbits', 'Recombinant Proteins', 'Rheology', 'Salts', 'Tensile Strength... | 24,504,411 | [['B01.050'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['G11.427.213.140', 'G16.762.150.150'], ['A02.835.232', 'A10.165.265'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D05.750.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Help-seeking behaviour for pelvic floor dysfunction in women over 55: drivers and barriers. | OBJECTIVE: Our aim was to identify drivers of and barriers to help-seeking behaviour of older women with pelvic floor dysfunction (PFD) living independently in Australia .METHODS: Women aged ?55 years were recruited to this cross-sectional study during July and August 2016. Bladder, bowel, pelvic organ prolapse (POP) a... | ['Australia', 'Cross-Sectional Studies', 'Diagnostic Self Evaluation', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Middle Aged', 'Patient Acceptance of Health Care', 'Pelvic Floor Disorders', 'Severity of Illness Index', 'Sexual Dysfunction, Physiological', 'Surveys and Questionnaires'] | 29,552,740 | [['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.360', 'F01.752.747.792.220'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.30... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Gait affects tibial component fixation. | The prognosis of fixation in patients with total knee arthroplasty was classified as either good or poor based on migration results over 4 to 8 years using roentgen stereophotogrammetry. Gait analysis with the Vicon system was performed in 27 asymptomatic patients (1 bilateral), selected according to gender, implant de... | ['Aged', 'Aged, 80 and over', 'Female', 'Gait', 'Humans', 'Knee Prosthesis', 'Male', 'Photogrammetry', 'Prosthesis Failure', 'Tibia'] | 10,475,559 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400.410'], ['E01.370.350.600.630'], ['C23.550.767.865', 'E05.325.771'], ['A02.835.232.043.650.883']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Analysis of damage due to moist heat treatment of spores of Bacillus subtilis. | AIMS: To determine conditions for generation and recovery of Bacillus subtilis spore populations heavily damaged by moist heat treatment.METHODS AND RESULTS: Bacillus subtilis spores were treated with moist heat and spore viability was assessed on different media. A rich medium and several minimal media gave similar sp... | ['Bacillus subtilis', 'Hot Temperature', 'Sodium Chloride', 'Spores, Bacterial', 'Time Factors', 'Water'] | 19,226,400 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D01.210.450.150.875', 'D01.857.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[ABO blood group typing for infants and its application for clinical transfusion]. | To study the correct method for determining ABO blood types in infants and its influencing factors, blood types of 33 infants under 6 months old were determined by routine serological method, micro-column gel typing system and PCR-SSP genotyping method. Of the 33 cases with discrepant results of ABO blood type by diffe... | ['ABO Blood-Group System', 'Blood Grouping and Crossmatching', 'Blood Transfusion', 'DNA', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Polymerase Chain Reaction', 'Reproducibility of Results'] | 12,844,418 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['E01.370.225.625.120', 'E01.370.225.812.385.120', 'E05.200.625.120', 'E05.200.812.385.120', 'E05.478.594.385.120'], ['E02.095.135'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.393.620.500'], ['E05.318.37... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The lengths' difference of legs in view of the general physician (author's transl)]. | The present paper treats the problem of the lengths' difference of legs in view of the general physician. After a five years' research a survey has been established and a classification in four groups has been made. Moreover the question of diagnosis and therapy has been treated. The requirement has been raised to diag... | ['Adult', 'Child', 'Female', 'Humans', 'Leg Length Inequality', 'Male', 'Scoliosis', 'Shoes'] | 463,225 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intraocular pressure in school myopia. | The relationship between intraocular pressure and ocular refraction and axial length were studied in a follow-up of myopic children and in a cross-section sample of school children. In the follow-up group intraocular pressure significantly decreased with age. Mean intraocular pressure at the mean age of 10.9 years was ... | ['Adolescent', 'Age Factors', 'Analysis of Variance', 'Child', 'Cross-Sectional Studies', 'Eye', 'Female', 'Follow-Up Studies', 'Humans', 'Intraocular Pressure', 'Male', 'Myopia', 'Random Allocation', 'Refraction, Ocular', 'Schools', 'Sex Factors', 'Tonometry, Ocular'] | 2,275,351 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A01.456.505.420', 'A09.371'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
pH regulation in perfused rat liver: respective role of Na(+)-H+ exchanger and Na(+)-HCO3- cotransport. | Na(+)-H+ antiport and Na(+)-HCO3- symport are involved in intracellular pH (pHi) homeostasis in cultured hepatocytes. We have studied the occurrence of these transport systems in the intact rat liver by 31P nuclear magnetic resonance. Livers perfused with a Krebs medium (25 mM HCO3-, pH 7.4, 37 degrees C) displayed a c... | ["4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid", 'Acidosis', 'Amiloride', 'Animals', 'Carrier Proteins', 'Hydrogen-Ion Concentration', 'Intracellular Membranes', 'Liver', 'Magnetic Resonance Spectroscopy', 'Male', 'Perfusion', 'Rats', 'Rats, Wistar', 'Sodium-Bicarbonate Symporters', 'Sodium-Hydrogen Excha... | 8,393,299 | [['D02.455.426.559.389.150.700.050', 'D02.500.375.050', 'D02.886.250.050'], ['C18.452.076.176'], ['D03.383.679.149'], ['B01.050'], ['D12.776.157'], ['G02.300'], ['A11.284.149.450', 'A11.284.835.514'], ['A03.620'], ['E05.196.867.519'], ['E05.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative evaluation of peer review of program project and center applications in allergy and immunology. | We compared the review patterns of applications for program projects and centers in allergy and immunology, reviewed by the National Institute of Allergy and Infectious Diseases review committee, with those of individual research projects in immunology, reviewed by three Division of Research Grants study sections. A hi... | ['Allergy and Immunology', 'National Institutes of Health (U.S.)', 'Peer Review', 'Research Support as Topic', 'United States'] | 4,044,784 | [['H02.403.044'], ['I01.409.418.750.600.650.496', 'N03.540.052.750', 'N03.540.348.500.500.600.650.496'], ['F01.829.316.549', 'I01.880.604.640', 'N03.706.700'], ['N03.219.483.645'], ['Z01.107.567.875']] | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Regulation of vascular endothelial growth factor expression by insulin-like growth factor-II in human keratinocytes, differential involvement of mitogen-activated protein kinases and feedback inhibition of protein kinase C. | BACKGROUND: Vascular endothelial growth factor (VEGF) is overexpressed in hyperproliferative diseases such as psoriasis and cancer, which are characterized by an increased angiogenesis. It was reported that insulin-like growth factor (IGF)-II is highly expressed during hepatocarcinogenesis and is increased in psoriatic... | ['Cells, Cultured', 'Enzyme Inhibitors', 'Gene Expression Regulation', 'Humans', 'Insulin-Like Growth Factor II', 'Keratinocytes', 'Mitogen-Activated Protein Kinases', 'Protein Kinase C', 'Protein-Tyrosine Kinases', 'Signal Transduction', 'Type C Phospholipases', 'Vascular Endothelial Growth Factor A'] | 15,787,809 | [['A11.251'], ['D27.505.519.389'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.420', 'D12.776.124.862.425', 'D12.776.467.937.420', 'D23.529.937.420'], ['A11.409.500', 'A11.436.397'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['D08.811.913.696.620.682.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Iodine nutrition in school children of four census areas of Chile]. | BACKGROUND: Although endemic goiter is an easily controlled chronic disease, it continues to be a serious global public health problem.AIM: To study iodine nutrition in school age children from different areas of Chile.SUBJECTS AND METHODS: Thyroid gland was palpated in 4181 school age children from Calama, Santiago, T... | ['Censuses', 'Child', 'Chile', 'Female', 'Food, Fortified', 'Goiter, Endemic', 'Humans', 'Iodine', 'Legislation, Food', 'Male', 'Nutritional Requirements', 'Prevalence', 'Sodium Chloride, Dietary'] | 9,609,050 | [['I01.240.205', 'N01.224.175', 'N06.850.505.400.225'], ['M01.060.406'], ['Z01.107.757.235'], ['G07.203.300.515', 'J02.500.515'], ['C19.874.283.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400'], ['N03.706.615.412'], ['G07.203.650.620'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.8... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equ... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Isolation and properties of goat beta 2-microglobulin. | Goat beta 2-microglobulin was isolated and purified from colostrum. Comparisons of the amino acid composition and amino-terminal sequence of the goat protein with the bovine and human homologues, indicates a high degree of similarity. Both goat and bovine beta 2-microglobulins differ slightly in composition from the hu... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'Chromatography, DEAE-Cellulose', 'Chromatography, Ion Exchange', 'Colostrum', 'Electrophoresis, Disc', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Goats', 'Humans', 'Immunodiffusion', 'Pregnancy', 'Species Specificity', 'beta 2-Microglobulin'] | 3,928,240 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.383.349'], ['E05.196.181.400.383'], ['A12.200.194'], ['E05.196.401.402.236', 'E05.301.300.319.403'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Efficacy of twice weekly iron supplementation in anemic adolescent girls. | Two hundred and forty four girls with different hemoglobin levels were selected, of which forty-one were non-anemic. The rest were graded as mildly, moderately or severely anemic and supplemented with 60 mg of iron daily or twice weekly for twelve weeks. There was no significant difference in the increase in hemoglobin... | ['Adolescent', 'Anemia, Iron-Deficiency', 'Developing Countries', 'Dietary Supplements', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'Humans', 'India', 'Iron, Dietary', 'Prospective Studies', 'Risk Assessment', 'Sampling Studies', 'Severity of Illness Index', 'Trea... | 14,722,370 | [['M01.060.057'], ['C15.378.071.196.300', 'C18.452.565.100'], ['I01.615.500.300'], ['G07.203.300.456', 'J02.500.456'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z0... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
A Neural Marker of Obsessive-Compulsive Disorder from Whole-Brain Functional Connectivity. | Obsessive-compulsive disorder (OCD) is a common psychiatric disorder with a lifetime prevalence of 2-3%. Recently, brain activity in the resting state is gathering attention for exploring altered functional connectivity in psychiatric disorders. Although previous resting-state functional magnetic resonance imaging stud... | ['Adult', 'Algorithms', 'Biomarkers', 'Brain', 'Brain Mapping', 'Female', 'Humans', 'Machine Learning', 'Magnetic Resonance Imaging', 'Male', 'Nerve Net', 'Neural Pathways', 'Obsessive-Compulsive Disorder', 'Reproducibility of Results', 'Young Adult'] | 28,790,433 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['D23.101'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E01.370.350.825.500'], ['A08.511'], ['A08.612'], ['F03.080.600'], ['E05.31... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross-reactive autoantibodies to tyrosinase and tyrosinase-related protein-2 (TRP-2). | In the present study we describe the detection of TRP-2 antibodies in vitiligo patients using in vitro 35S-labelled human TRP-2 in a radioimmunoassay. Of 53 vitiligo sera examined in the assay, three (5 9%) were found to be positive for TRP-2 antibodies. In contrast, 20 control sera, sera from 10 patients with Hashimot... | ['Absorption', 'Adolescent', 'Adult', 'Aged', 'Animals', 'Autoantibodies', 'Autoantigens', 'Autoimmune Diseases', 'Autoimmunity', 'COS Cells', 'Cells, Cultured', 'Cloning, Molecular', 'Cross Reactions', 'Female', 'Gene Expression', 'Graves Disease', 'Humans', 'Intramolecular Oxidoreductases', 'Isomerases', 'Male', 'Mid... | 9,328,128 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['C20.111'], ['G12.450.192'], ['A11.251.210.172.500', 'A11.329.228.220... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationship between plaque pH and different caries-associated variables in a group of adolescents with varying caries prevalence. | The pH response of the dental biofilm after a sugar challenge can be considered to mirror the acidogenic potential and thereby the caries risk of an individual. The aim of this cross-sectional study was to evaluate the relationship between plaque pH and different caries variables in adolescents with varying caries prev... | ['Adolescent', 'Bacterial Load', 'Buffers', 'Cariostatic Agents', 'Cross-Sectional Studies', 'DMF Index', 'Dental Caries Susceptibility', 'Dental Plaque', 'Dental Plaque Index', 'Dietary Sucrose', 'Feeding Behavior', 'Fluorides', 'Humans', 'Hydrogen-Ion Concentration', 'Lactobacillus', 'Oral Hygiene', 'Risk Assessment'... | 24,401,692 | [['M01.060.057'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['D27.720.470.280'], ['D25.223', 'D27.505.696.706.222', 'D27.720.102.223', 'D27.720.799.113', 'J01.637.051.223'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Hypotensive and reflex bradycardic effects of ketanserin, but not of prazosin, enhanced selectively in aging conscious rats. | To determine whether cardiovascular effects of ketanserin are altered differently with aging as compared with those of prazosin, we recorded blood pressure (BP) and heart rate (HR) changes produced by treatment with either drug in three age groups of conscious Sprague-Dawley rats. BP was decreased more by ketanserin in... | ['Adrenergic alpha-1 Receptor Agonists', 'Adrenergic alpha-Agonists', 'Aging', 'Angiotensin II', 'Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Heart Rate', 'Injections, Intravenous', 'Ketanserin', 'Male', 'Nitroprusside', 'Phenylephrine', 'Prazosin', 'Rats', 'Rats, Sprague-Dawley', 'Regional Blood Flow', 'Va... | 8,856,487 | [['D27.505.519.625.050.100.100.100', 'D27.505.696.577.050.100.100.100'], ['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['G07.345.124'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['D27.505... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A double-blind controlled study of granulocyte colony-stimulating factor started two days before induction chemotherapy in refractory acute myeloid leukemia. Kohseisho Leukemia Study Group. | We conducted a prospective, double-blind controlled study to determine the efficacy of a recombinant granulocyte colony-stimulating factor (G-CSF, 200 microgram/m2) starting daily from 2 days before an induction therapy until neutrophils recovered to above 1,500/microL or until 35 days after the therapy in 58 patients ... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Bacterial Infections', 'Double-Blind Method', 'Female', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Neutrophils', 'Prospective Studies', 'Survival Rate'] | 7,512,838 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C01.150.252'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.350', 'D23.529.374.410... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Investigation of an acoustic-mechanical method to detect implant loosening. | Precise diagnosis of loosening of endoprosthetic implants plays an important role in timely, adequate treatment. However, today's diagnostic tools, mainly radiological evaluation, do not yield satisfactory results. Therefore, a new approach based on the transmission of an internally generated combined acoustic and vibr... | ['Acoustics', 'Equipment Failure Analysis', 'Mechanical Phenomena', 'Reproducibility of Results', 'Vibration'] | 23,860,369 | [['H01.671.031'], ['E05.325.192'], ['G01.374'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G01.374.930']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Immunologic properties of various cell fractions of a wild strain and a mutant strain of Saccharomyces cerevisiae Hansen]. | Some fractions of the Saccharomyces cerevisiae cell wall have been prepared by the action of Helix pomatia juice on intact cells. Immunosera were obtained by injecting rabbits with these fractions. Immunofluorescence reactions, obtained with these sera, show that some fractions of mannopeptides when extracted from a "s... | ['Cell Wall', 'Epitopes', 'Fluorescent Antibody Technique', 'Fungal Proteins', 'Glycopeptides', 'Mutation', 'Saccharomyces cerevisiae', 'Subcellular Fractions'] | 70,263 | [['A11.284.183'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['D12.776.354'], ['D09.400.420', 'D12.644.233'], ['G05.365.590'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['A11.284.835']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serological and genomic characterization of L338, a novel equine group A rotavirus G serotype. | A group A rotavirus designated L338 was isolated from the faeces of a diarrhoeic foal and was compared to 11 standard G serotype strains of group A rotaviruses by cross-neutralization. It was clearly distinct from serotypes G1 to G11 and thus representative of a novel rotavirus G serotype tentatively designated G13. Th... | ['Amino Acid Sequence', 'Animals', 'Antigens, Viral', 'Base Sequence', 'Capsid', 'Capsid Proteins', 'Cross Reactions', 'Electrophoresis, Polyacrylamide Gel', 'Genes, Viral', 'Horses', 'Immune Sera', 'Molecular Sequence Data', 'Neutralization Tests', 'Rotavirus', 'Sequence Homology, Nucleic Acid', 'Serotyping'] | 1,851,806 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.327'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A21.249.500.250'], ['D12.776.964.970.600.550'], ['G12.122.281'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Methotrexate preferentially affects Tc1 and Tc17 subset of CD8 T lymphocytes. | Rheumatoid arthritis is considered a T-lymphocyte-mediated disease. However, studies have focussed on CD4 T-lymphocytes, ignoring CD8 T-lymphocytes despite the latter being found abundantly in the synovium. Specifically, there is little data of the effect of methotrexate, the gold-standard DMARD, on various CD8 cytokin... | ['Adolescent', 'Adult', 'Aged', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'CD8-Positive T-Lymphocytes', 'Female', 'Flow Cytometry', 'Humans', 'India', 'Interleukin-17', 'Male', 'Methotrexate', 'Middle Aged', 'Prospective Studies', 'T-Lymphocyte Subsets', 'Young Adult'] | 29,464,523 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.60... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Age decreases nitric oxide synthase-containing nerve fibers in the rat penis. | PURPOSE: To study the effect of aging on erectile function in a rat model.MATERIALS AND METHODS: We investigated: 1) the number and distribution of nerve fibers within the corpus cavernosum and dorsal nerve containing vasoactive intestinal polypeptide (VIP) and nitric oxide synthase (NOS); and 2) the erectile response ... | ['Aging', 'Animals', 'Apomorphine', 'Dopamine Agonists', 'Electric Stimulation', 'Male', 'Nerve Fibers', 'Nitric Oxide Synthase', 'Papaverine', 'Penile Erection', 'Penis', 'Rats', 'Rats, Sprague-Dawley', 'Vasoactive Intestinal Peptide', 'Vasodilator Agents'] | 9,072,549 | [['G07.345.124'], ['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['E05.723.402'], ['A08.675.542', 'A11.671.501'], ['D08.811.682.664.500.772'], ['D03.132.098.666', 'D03.132.577.750', 'D03.633.100.531.085.666'], ['G08.686... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polymorphic trophonosis: the pseudo-omnivorous diet-related disease--a hypothesis. | Consideration of a wide range of seemingly disparate, non-infectious diseases reveals that most of them are only the varying forms or symptoms of a single, diet-related disease postulated to be Polymorphic Trophonosis. It is pointed out that they are all associated with pseudo-omnivorous dietary practices--negating the... | ['Animals', 'Arteriosclerosis', 'Coronary Disease', 'Deficiency Diseases', 'Diabetes Mellitus', 'Diet', 'Dietary Fiber', 'Humans', 'Hypoglycemia', 'Intestinal Diseases', 'Models, Biological', 'Nutrition Disorders'] | 6,255,299 | [['B01.050'], ['C14.907.137.126'], ['C14.280.647.250', 'C14.907.585.250'], ['C18.654.521.500'], ['C18.452.394.750', 'C19.246'], ['G07.203.650.240'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['C06.405.469'], ['E05.599.395'], ['C18.654']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Novel TMPRSS3 variants in Pakistani families with autosomal recessive non-syndromic hearing impairment. | Mutations in the TMPRSS3 gene are known to cause autosomal recessive non-syndromic hearing impairment (ARNSHI). After undergoing a genome scan, 10 consanguineous Pakistani families with ARNSHI were found to have significant or suggestive evidence of linkage to the TMPRSS3 region. In order to elucidate if the TMPRSS3 ge... | ['Case-Control Studies', 'Chromosomes, Human, Pair 21', 'Consanguinity', 'Ear, Inner', 'Exons', 'Female', 'Genes, Recessive', 'Genetic Linkage', 'Genetic Loci', 'Hearing Loss', 'Humans', 'Male', 'Membrane Proteins', 'Models, Molecular', 'Mutation', 'Neoplasm Proteins', 'Pedigree', 'Phenotype', 'Protein Structure, Terti... | 21,534,946 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['G05.090.403.180', 'G05.180'], ['A09.246.300'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340.415', 'G05.420.325'], ['G05.348'], ['G05.360.340.024.380'], ['C09.218.45... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ectoglycosyltransferase activities at the surface of cultured neurons. | Glycosyltransferase activities (ectogalactosyl, ectofucosyl and ectosialyl) were studied at the external surface of exclusively neuronal cultures. An appropriate methodology gave the possibility to eliminate sources of errors due to the hydrolysis of nucleotide sugar substrates or due to cellular uptake of free sugars.... | ['Animals', 'Carbohydrate Metabolism', 'Cells, Cultured', 'Chick Embryo', 'Chickens', 'Glycosyltransferases', 'Hexosyltransferases', 'Neurons', 'Surface Properties'] | 6,870,868 | [['B01.050'], ['G02.111.158', 'G03.191'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D08.811.913.400'], ['D08.811.913.400.450'], ['A08.675', 'A11.671'], ['G02.860']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased production of interleukin 4 by CD4+ and CD8+ T cells from patients with tuberculosis is related to the presence of pulmonary cavities. | In tuberculosis, cellular immunity is considered to be responsible for the eradication of infection but also for damage of host tissues. In animal models, the balance between Th1-type cytokines, especially interferon (IFN)-gamma, and Th2-type cytokines, primarily interleukin (IL)-4, seems crucial for these effects. Rep... | ['Adolescent', 'Adult', 'Aged', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Female', 'Humans', 'Interferon-gamma', 'Interleukin-4', 'Male', 'Middle Aged', 'Tuberculosis, Pulmonary'] | 10,720,554 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serial stent implantation to relieve in-stent stenosis in obstructed total anomalous pulmonary venous return. | A nine-year-old girl with complex cyanotic heart disease associated with supracardiac total anomalous venous return and obstruction at the drainage site of the vertical vein into the left innominate vein had stent placement at the age of seven, with immediate increase of oxygen saturation and improvement of physical ac... | ['Child', 'Constriction, Pathologic', 'Female', 'Heart Defects, Congenital', 'Humans', 'Palliative Care', 'Pulmonary Circulation', 'Pulmonary Valve Insufficiency', 'Pulmonary Veins', 'Recurrence', 'Stents'] | 11,889,542 | [['M01.060.406'], ['C23.300.287'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.666', 'N02.421.585.666'], ['G09.330.100.770', 'G09.772.593'], ['C14.280.484.660'], ['A07.015.908.713'], ['C23.550.291.937'], ['E07.695.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acupuncture at HT7 suppresses morphine self-administration at high dose through GABA system. | In the previous study, acupuncture at HT7 has shown to attenuate the self-administration of morphine at a low dose (0.1mg/kg). In this study, it was further investigated whether acupuncture at HT7 could attenuate the morphine self-administration at a high dose (0.5mg/kg). Male Sprague-Dawley rats weighing 270-300g were... | ['Acupuncture Points', 'Animals', 'Bicuculline', 'GABA-A Receptor Antagonists', 'GABA-B Receptor Antagonists', 'Male', 'Morphine', 'Morphine Dependence', 'Morpholines', 'Motor Activity', 'Narcotics', 'Neurons', 'Rats, Sprague-Dawley', 'Receptors, GABA', 'Self Administration'] | 24,905,174 | [['E02.190.044.555.035'], ['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['D27.505.519.625.240.300.500', 'D27.505.696.577.240.300.500'], ['D27.505.519.625.240.300.750', 'D27.505.696.577.240.300.750'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Generating a taxonomy of spatially cued attention for visual discrimination: effects of judgment precision and set size on attention. | Attention precues improve the performance of perceptual tasks in many but not all circumstances. These spatial attention effects may depend upon display set size or workload, and have been variously attributed to external noise filtering, stimulus enhancement, contrast gain, or response gain, or to uncertainty or other... | ['Adult', 'Attention', 'Cues', 'Discrimination, Psychological', 'Humans', 'Judgment', 'Models, Psychological', 'Psychomotor Performance', 'Space Perception', 'Visual Perception'] | 24,939,234 | [['M01.060.116'], ['F02.830.104.214'], ['F02.463.425.234'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['E05.599.695'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.463.593.778'], ['F02.463.593.932']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blood pressure-lowering effects of lifestyle modification: possible involvement of nitric oxide bioavailability. | Lifestyle modification is recommended as a non-pharmacological approach to treatment of hypertension. Many investigators have reported that exercise has antihypertensive effects, and various mechanisms have been proposed to explain this phenomenon. For example, nitric oxide (NO), which may be increased by exercise, has... | ['Adult', 'Biological Availability', 'Blood Pressure', 'Cholesterol, HDL', 'Diet', 'Exercise', 'Female', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Nitric Oxide', 'Superoxide Dismutase'] | 16,471,171 | [['M01.060.116'], ['G03.787.151', 'G07.690.725.129'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['G07.203.650.240'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], [... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Clinical and pathological analysis of 41 cases of acute leukemia combined with intracranial hemorrhage]. | This study was aimed to summarize the clinical and pathological features of patients with acute leukemia combined with intracranial hemorrhage. The clinical and pathological data of 41 adult patients diagnosed as acute leukemia in our hospital from 1953 to 1990 year were analyzed retrospectively. The results showed tha... | ['Acute Disease', 'Adolescent', 'Adult', 'Female', 'Humans', 'Intracranial Hemorrhages', 'Leukemia', 'Male', 'Middle Aged', 'Retrospective Studies', 'Young Adult'] | 24,370,021 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.535', 'C14.907.253.573', 'C23.550.414.913'], ['C04.557.337'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo. | The triazine WR99210 [4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5-trichlorophenoxypropyloxy)-1,3,5 triazine] inhibits Toxoplasma gondii in vitro at nanomolar levels (P < 0.05). The 50% inhibitory concentration (IC(50)) was approximately 50 nM. It is a potent inhibitor in vitro and is also effective in vivo. Administr... | ['Animals', 'Antiprotozoal Agents', 'Cells, Cultured', 'Fibroblasts', 'Folic Acid Antagonists', 'Humans', 'Mice', 'Molecular Sequence Data', 'Parasitic Sensitivity Tests', 'Sequence Alignment', 'Tetrahydrofolate Dehydrogenase', 'Toxoplasma', 'Toxoplasmosis, Animal', 'Triazines'] | 16,048,961 | [['B01.050'], ['D27.505.954.122.250.100'], ['A11.251'], ['A11.329.228'], ['D27.505.519.389.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['E01.370.225.940', 'E05.200.940', 'E05.337.550.700'], ['E05.393.751'], ['D08.811.682.662.825'], ['B01.043.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Poor reproducibility of PIRADS score in two multiparametric MRIs before biopsy in men with elevated PSA. | PURPOSE: Since January 2015, all men referred to urologists in Norway due to elevated PSA or other suspicion of prostate cancer underwent multiparametric MRI (mpMRI) before prostate biopsy. At our hospital, patients and the initial MRI were assessed by an urologist and if deemed necessary, patients were referred to ano... | ['Aged', 'Biomarkers, Tumor', 'Decision Support Techniques', 'Dimensional Measurement Accuracy', 'Humans', 'Image-Guided Biopsy', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Norway', 'Predictive Value of Tests', 'Prostate', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Reproducibility of Results', 'Res... | 29,508,048 | [['M01.060.116.100'], ['D23.101.140'], ['E05.245', 'L01.313.500.750.190'], ['E05.318.370.725.500', 'E05.337.851.500', 'N05.715.360.325.685.500', 'N06.850.520.445.725.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.384.100.370', 'E01.370.225.998.054.370', 'E01.370.388.100.370', 'E04.074.370', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Isozyme and morphological characteristics of the anaerobic fungus Piromyces mae isolated from the duodenum, rumen and faeces of sheep. | Isolates of anaerobic fungi obtained from the rumen, duodenum and faeces of sheep were identified as Piromyces mae based on their morphological characteristics observed using light microscopy. There was no significant morphological variation among the isolates of P. mae from the rumen, duodenum and faeces. Isozymes of ... | ['Anaerobiosis', 'Animals', 'Duodenum', 'Feces', 'Fungal Proteins', 'Fungi', 'Isoenzymes', 'Male', 'Rumen', 'Sheep'] | 8,593,960 | [['G02.111.062', 'G03.078'], ['B01.050'], ['A03.556.124.684.124', 'A03.556.875.249'], ['A12.459'], ['D12.776.354'], ['B01.300'], ['D08.811.348', 'D12.776.800.300'], ['A13.869.804'], ['B01.050.150.900.649.313.500.380.791']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta. | Urokinase (uPA)-induced signaling in human vascular smooth muscle cells (VSMC) elicits important cellular functional responses, such as cell migration and proliferation. However, how intracellular signaling is linked to glycolipid-anchored uPA receptor (uPAR) is unknown. We provide evidence that uPAR activation by uPA ... | ['Cells, Cultured', 'DNA-Binding Proteins', 'Dimerization', 'Humans', 'Muscle, Smooth, Vascular', 'Phosphorylation', 'Receptor, Platelet-Derived Growth Factor beta', 'STAT1 Transcription Factor', 'Trans-Activators', 'Urokinase-Type Plasminogen Activator', 'rhoA GTP-Binding Protein'] | 15,889,147 | [['A11.251'], ['D12.776.260'], ['G02.206', 'G03.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D08.811.913.696.620.682.725.400.900.750', 'D12.776.543.750.630.625.400', 'D12.776.543.750.750.400.630.400'], ['D... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Longitudinal optical trapping and sizing of aerosol droplets. | We present evidence that aerosol droplets, approximately 1-2microm in diameter, can be optically bound over a 4mm distance within a volume formed by the overlap of the central cores and rings of two counterpropagating Bessel beams. The sizes of the individual polydisperse aerosol particles can be estimated from the ang... | ['Aerosols', 'Lasers', 'Nebulizers and Vaporizers', 'Optical Tweezers', 'Particle Size', 'Scattering, Radiation', 'Water'] | 20,588,558 | [['D20.280.055', 'D26.255.165.055'], ['E07.632.490', 'E07.710.520'], ['E07.605'], ['E05.650'], ['G02.712'], ['E05.196.822', 'G01.867'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studying abroad: a multiple case study of nursing students' international experiences. | This paper examines the experiences of nursing students undertaking an international placement during their pre-registration education. The study took place in two schools--one in the United Kingdom, and one in Sweden. The move of nursing education into higher education enabled students to participate in international ... | ['Adaptation, Psychological', 'Adult', 'Attitude of Health Personnel', 'Cultural Competency', 'Education, Nursing, Baccalaureate', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'International Educational Exchange', 'Male', 'Middle Aged', 'Models, Educational', 'Models, Nursing', 'Models, Psychological', ... | 18,692,278 | [['F01.058'], ['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['I01.880.853.100.364'], ['I02.358.462.316'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500.650', 'I02.581'], ['M01.060.116.630'], ['E05.599.545', 'I02.903.302'], ['E05.599.645'], ['E05.599.695'], ['F... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[The development of SPA bone densitometry for heel bone]. | The design principles of a bone densitometer for heel bone based on SPA are introduced here, which include the principles of mechanical system and control system. The main technical index and advantages of the device have also been discussed in the paper. | ['Absorptiometry, Photon', 'Bone Density', 'Calcaneus', 'Equipment Design', 'Evaluation Studies as Topic', 'Humans'] | 12,583,264 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['G11.427.100'], ['A02.835.232.043.300.710.300'], ['E05.320'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Will stringent total nitrogen wastewater treatment plant discharge regulations achieve stream water quality goals? | The Colorado Department of Public Health and Environment (CDPHE) proposed the in-stream numeric nutrient criteria as 2 mg TN per L and 0.16 mg TP per L for warm surface waters and 0.40 mg TN per L and 0.11 mg TP per L for cold surface waters. Consequently the department presented the nutrient limits for the municipal w... | ['Environmental Monitoring', 'Environmental Policy', 'Nitrogen', 'Rivers', 'Waste Disposal, Fluid', 'Waste Water', 'Water Pollutants, Chemical', 'Water Pollution, Chemical', 'Water Quality'] | 23,032,438 | [['N06.850.460.350.080', 'N06.850.780.375'], ['I01.655.500.608.180', 'I01.880.604.825.608.180', 'N03.623.500.608.180', 'N06.230.204'], ['D01.268.604', 'D01.362.625'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.7... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
The lumbar roots and pedicles: a morphometric analysis and anatomical features. | The objective of this study was to conduct a morphometric analysis of the lumbar nerve roots and surrounding structures. In this investigation, the lumbar roots were studied in 14 cadavers (70 lumbar vertebrae). Lumbar pedicle heights and widths were measured at every level of the lumbar vertebrae. The largest mean roo... | ['Adolescent', 'Adult', 'Aged', 'Cadaver', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Spinal Nerve Roots'] | 18,486,477 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['A08.800.800.720.725']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preparation of a novel organo-soluble chitosan grafted polycaprolactone copolymer for drug delivery. | The unsatisfactory solubility of chitosan has been a key barrier to its modification and application. To improve its solubility, a novel organo-soluble glycidol grafted chitosan was developed as a potential material for bio-related applications. The hydrophilic glycidol was grafted onto the amino groups of chitosan via... | ['Antineoplastic Agents', 'Chitosan', 'Dimethyl Sulfoxide', 'Dimethylformamide', 'Doxorubicin', 'Drug Carriers', 'Epoxy Compounds', 'Hep G2 Cells', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Polyesters', 'Propanols', 'Solubility'] | 24,418,345 | [['D27.505.954.248'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D02.886.640.150'], ['D02.065.463.387', 'D02.241.081.420.500.387'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D26.255.260', 'E02.319.300.380'], ['D02.355.291.411'], ['A11.251.860.180.432', 'A11.436.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Age-related reduction of structural complexity in spleen hematopoietic tissue architecture in mice. | The effects of aging on structural complexity in hematopoietic tissue are unknown. In this work, in a mouse experimental model, we report the age-related reduction of spleen hematopoietic tissue (SHT) complexity. Spleen tissue was obtained from the total of 64 male Swiss albino mice divided into 8 age groups: newborns ... | ['Aging', 'Animals', 'Coloring Agents', 'Fractals', 'Hematopoietic Stem Cells', 'Male', 'Mice', 'Spleen', 'Tolonium Chloride'] | 23,834,968 | [['G07.345.124'], ['B01.050'], ['D27.720.233'], ['E05.599.125', 'G17.290'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.992.635.505.500'], ['A10.549.700', 'A15.382.520.604.700'], ['D02.886.369.869', 'D03.633.300.783.869']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A chloroquine resistance locus in the rodent malaria parasite Plasmodium chabaudi. | We have located a possible chloroquine resistance locus in the genome of the rodent malaria parasite Plasmodium chabaudi. Two genetically distinct clones of the parasite were grown in vivo and allowed to undergo genetic crossing. The clones differed from each other in their susceptibility to chloroquine; AS(3CQ) had be... | ['Animals', 'Antimalarials', 'Chloroquine', 'Chromosome Mapping', 'Crosses, Genetic', 'Dose-Response Relationship, Drug', 'Drug Resistance, Multiple', 'Genes, Protozoan', 'Genetic Linkage', 'Genetic Markers', 'HSP90 Heat-Shock Proteins', 'Male', 'Meiosis', 'Mice', 'Plasmodium chabaudi', 'Rats'] | 9,662,028 | [['B01.050'], ['D27.505.954.122.250.100.085'], ['D03.633.100.810.050.180'], ['E05.393.183'], ['E05.393.281'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984.300'], ['G05.360.340.024.340.396', 'G05.360.340.397.500'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['D12.776.580.216.380'], ['G04.144.220.220.687',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NT-proBNP levels and mortality in a general population-based cohort from Turkey: a long-term follow-up study. | AIM: We investigated the relationship between NT-ProBNP and mortality in a general population-based cohort.METHODS & RESULTS: A total of 2021 out of 4650 participants from previously published HAPPY study were included. Mean follow-up was 84.5 ± 10.4 months. After adjusting for risk factors, high levels of LogNT-proBNP... | ['Adult', 'Area Under Curve', 'Biomarkers', 'Cardiovascular Diseases', 'Female', 'Follow-Up Studies', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Prognosis', 'Proportional Hazards Models', 'ROC Curve', 'Regression Analysis', 'Risk Factors', 'Turkey'] | 30,191,742 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101'], ['C14'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes, and their precursors. | Leukocytes with ring-shaped nuclei (ring cells) are present in bone marrow (BM; approximately 50% of BM cells), in peripheral blood (PB), and in inflammatory infiltrates of mice, but also in humans during myeloproliferative disorders. They are usually referred to as polymorphonuclear cells (PMN), but we demonstrate tha... | ['Animals', 'Apoptosis', 'Blood Cell Count', 'Cell Adhesion', 'Cell Division', 'Cell Nucleus', 'Cell Separation', 'Immunohistochemistry', 'Inflammation', 'Mice', 'Mice, Inbred BALB C', 'Microscopy, Electron', 'Neutrophils', 'Peroxidases', 'Phagocytosis'] | 10,088,605 | [['B01.050'], ['G04.146.954.035'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['G04.022'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The effectiveness of the '2-week wait' referral service for colorectal cancer. | INTRODUCTION: The UK government target expects all suspected cancer patients to be seen within 2 weeks of referral made by general practitioners. This has significant impact on the workload for colorectal surgeons. The aim of this study was to investigate the effectiveness of this colorectal service.METHOD: A retrospec... | ['Adult', 'Aged', 'Colorectal Neoplasms', 'Early Detection of Cancer', 'Humans', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Program Evaluation', 'Referral and Consultation', 'Retrospective Studies', 'Waiting Lists'] | 20,946,272 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.390.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E01.789'], ['E05.337.820', 'N04... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kinetic studies on the adsorption of phenol, 4-chlorophenol, and 2,4-dichlorophenol from water using activated carbons. | This study uses rate parameters in pseudo-first-order (PFO) and pseudo-second-order (PSO) equations (k(1) and k(2)q(e), respectively) to judge the extent for approaching equilibrium in an adsorption process. Out of fifty-six systems collected from the literature, the adsorption processes with a k(2)q(e) value between 0... | ['Biodegradation, Environmental', 'Charcoal', 'Chlorophenols', 'Phenols', 'Pistacia', 'Sodium Hydroxide', 'Surface Properties', 'Water Pollutants, Chemical', 'Water Purification'] | 20,621,413 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.150.150'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['D02.455.426.559.389.657'], ['B01.650.940.800.575.912.250.044.555'], ['D01.045.250.750', 'D01.248.497.158.459.475', 'D01.857.745'], ['G02.860'], ['D27.888.284.903.655'], ['N06.850.780.2... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Radiologic aspects of abdominal hydatidosis in children: a study of 31 cases in Turkey. | OBJECTIVE: To determine the location and radiological characteristics in children with abdominal hydatid disease (HD).MATERIALS AND METHODS: Thirty-one children (average age: 7.2 years) with abdominal HD were studied. The number, location, diameter and internal architecture of the cysts were assessed with abdominal ult... | ['Abdominal Cavity', 'Absorptiometry, Photon', 'Child', 'Child, Preschool', 'Echinococcosis', 'Echinococcosis, Hepatic', 'Female', 'Humans', 'Male', 'Peritoneal Cavity', 'Radiographic Image Enhancement', 'Splenic Diseases', 'Tomography, X-Ray Computed', 'Turkey', 'Ultrasonography'] | 15,158,224 | [['A01.923.047.025'], ['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.406'], ['M01.060.406.448'], ['C01.610.335.190.396'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.047.025.600.678'], ['E01.370.350.600.350.700', 'E01.370.350.7... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Exercise-induced cellular alterations in the diaphragm. | Limited data exist concerning the effects of exercise training on cellular oxidative capacity in the diaphragm of senescent animals. In this study we examined the changes in cellular oxidative capacity, muscle cell cross-sectional area (CSA), and capillarity within the costal diaphragm of senescent animals after a 10-w... | ['Aging', 'Animals', 'Body Weight', 'Capillaries', 'Diaphragm', 'Female', 'Foot', 'Muscles', 'Oxidation-Reduction', 'Physical Conditioning, Animal', 'Physical Endurance', 'Physical Exertion', 'Rats', 'Rats, Inbred F344', 'Succinate Dehydrogenase'] | 1,443,227 | [['G07.345.124'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A07.015.461.165'], ['A02.633.567.900.300'], ['A01.378.610.250'], ['A02.633', 'A10.690'], ['G02.700', 'G03.295.531'], ['G11.427.410.698.277.280'], ['G11.427.680', 'I03.450... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Design of experiment for optimization of plasma-polymerized octafluorocyclobutane coating on very high aspect ratio silicon molds. | As-fabricated deep reactive ion etched (DRIE) silicon mold with very high aspect ratio (>10) feature patterns is unsuitable for poly(dimethylsiloxane) (PDMS) replication because of the strong interaction between the Si surface and the replica and the corrugated mold sidewalls. The silicon mold can be conveniently passi... | ['Biocompatible Materials', 'Chlorofluorocarbons', 'Chlorofluorocarbons, Methane', 'Coated Materials, Biocompatible', 'Dimethylpolysiloxanes', 'Equipment Design', 'Fluorine', 'Microscopy, Electron, Scanning', 'Models, Statistical', 'Models, Theoretical', 'Nylons', 'Silicon', 'Spectrometry, X-Ray Emission', 'Surface Pro... | 17,107,021 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D02.455.526.439.220', 'D02.455.526.510.140'], ['D02.455.526.439.220.300', 'D02.455.526.510.140.300'], ['D25.130.420', 'J01.637.051.130.420'], ['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['E05.320'], ['D01.268... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mandibular osteoradionecrosis: reconstructive surgery. | Osteoradionecrosis of the mandible is a serious complication following radiotherapy of head and neck cancers. A retrospective study of 20 reconstructions of mandibular defects due to osteoradionecrosis was performed. Various osseocutaneous free flaps were used: upper lateral arm (n = 5), radial forearm (n = 1), iliac c... | ['Adult', 'Aged', 'Female', 'Humans', 'Jaw Fixation Techniques', 'Male', 'Mandibular Diseases', 'Microsurgery', 'Middle Aged', 'Osteoradionecrosis', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Surgical Flaps', 'Treatment Outcome', 'Vascular Surgical Procedures'] | 12,071,997 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.545.440', 'E06.645.440'], ['C05.500.607', 'C07.320.610'], ['E04.494', 'E05.591.580'], ['M01.060.116.630'], ['C26.733.579', 'G01.750.748.500.579'], ['E04.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.36... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Introduction to pion radiotherapy. | In recent years, radiation therapy has seen an influx of experimental treatment beams. The negative pi meson, or pion, is one such beam. It exhibits complex phenomena that may prove to be a major advance in the radiation therapy of some tumors. This paper discusses the pion beam at the Los Alamos Scientific Laboratory,... | ['Clinical Trials as Topic', 'Elementary Particles', 'Humans', 'Melanoma', 'Radiobiology', 'Radiotherapy', 'Skin', 'Skin Neoplasms'] | 331,391 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['G01.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['H01.158.273.789'], ['E02.815'], ['A17.815'], ['C04.588.805', 'C17.800.882']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Immunological responses of Eurasian badgers (Meles meles) vaccinated with Mycobacterium bovis BCG (bacillus calmette guerin). | Wildlife species, such as the badger (Meles meles), may act as maintenance hosts for Mycobacterium bovis and contribute to the spread and persistence of tuberculosis in associated cattle populations. Targeted vaccination of badgers against tuberculosis is an option that, if successfully employed, could directly facilit... | ['Animals', 'Antibodies, Bacterial', 'BCG Vaccine', 'Carnivora', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Lymphocyte Activation', 'Male', 'Mycobacterium bovis', 'T-Lymphocytes', 'Tuberculosis', 'Vaccination'] | 11,389,955 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D20.215.894.135.825.100'], ['B01.050.150.900.649.313.750'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.812.482', 'E05.200... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Questionnaire on switching from the tiotropium HandiHaler to the Respimat inhaler in patients with chronic obstructive pulmonary disease: changes in handling and preferences immediately and several years after the switch. | BACKGROUND: Tiotropium (Spiriva) is an inhaled muscarinic antagonist for patients with chronic obstructive pulmonary disease (COPD), and is available in two forms: the HandiHaler and the Respimat inhaler. The aim of this study was to investigate the handling of and preference for each device immediately after switching... | ['Administration, Inhalation', 'Aged', 'Aged, 80 and over', 'Bronchodilator Agents', 'Equipment Design', 'Female', 'Forced Expiratory Volume', 'Health Care Surveys', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Muscarinic Antagonists', 'Nebulizers and Vaporizers', 'Patient Preference', 'Pulmonary Disease, Chronic Obstruct... | 25,609,941 | [['E02.319.267.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['E05.320'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social, psychological and physical correlates of eating problems. A study of the general adolescent population in Norway. | The characteristics and concurrent predictors of eating problems were identified. Ninety-seven per cent of a representative sample of Norwegian adolescents (N = 11315) completed a questionnaire containing a 12-item version of the Eating Attitudes Test (EAT) and measures of a large number of physiological, psychological... | ['Adolescent', 'Anorexia Nervosa', 'Body Image', 'Body Mass Index', 'Body Weight', 'Bulimia', 'Cohort Studies', 'Cross-Sectional Studies', 'Diet, Reducing', 'Educational Status', 'Exercise', 'Female', 'Gender Identity', 'Humans', 'Incidence', 'Norway', 'Puberty', 'Risk Factors', 'Self Concept', 'Social Values', 'Substa... | 7,480,437 | [['M01.060.057'], ['F03.400.125'], ['F01.752.747.792.110', 'F02.463.593.112'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C23.888.821.645.500'], ['E05... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells. | BACKGROUND: Cytokine-induced killer (CIK) cells are ex vivo-expanded immune cells that express NK-cell and T-cell markers and that are routinely used in the treatment of many cancers. One key advantage of CIK cells is their ability to efficiently traffic to many solid tumours. Although likely to be mediated by chemokin... | ['Animals', 'Cell Proliferation', 'Cytokine-Induced Killer Cells', 'Cytotoxicity, Immunologic', 'Flow Cytometry', 'HeLa Cells', 'Humans', 'Killer Cells, Natural', 'Mice', 'Neoplasms', 'Receptors, Chemokine'] | 24,642,619 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.118.637.555.283', 'A11.251.476', 'A15.145.229.637.555.283', 'A15.382.490.555.283'], ['G12.287'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence for recombination between feline panleukopenia virus and canine parvovirus type 2. | Canine parvovirus type 2 (CPV) is a virulent pathogen that emerged in the late 1970s, probably originating from feline panleukopenia virus (FPLV) or a closely related carnivore parvovirus belonging to the feline parvovirus (FPV) subspecies. In contrast to FPLV, CPV has evolved rapidly since its emergence. The original ... | ['Animals', 'Cats', 'Dog Diseases', 'Dogs', 'Feline Panleukopenia', 'Feline Panleukopenia Virus', 'Parvoviridae Infections', 'Parvovirus, Canine', 'Phylogeny', 'Recombination, Genetic', 'Sequence Alignment'] | 19,420,841 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C01.925.256.700.363', 'C22.180.460'], ['B04.280.580.650.600.325'], ['C01.925.256.700'], ['B04.280.580.650.600.325.660'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.728'], ['E05.393.751']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of cyclosporin A immunosuppression on pancreaticoduodenal transplantation in alloxan-diabetic rats. | 1. Forty-five outbred Wistar rats were randomly assigned to three experimental groups: GI, 10 non-diabetic control rats; GII, 10 alloxan-diabetic control rats; GIII, 25 alloxan-diabetic rats which received pancreaticoduodenal transplantation (PDT) from normal Wistar donor rats and were immunosuppressed with cyclosporin... | ['Animals', 'Cyclosporine', 'Diabetes Mellitus, Experimental', 'Drug Evaluation', 'Duodenum', 'Female', 'Immunohistochemistry', 'Immunosuppression', 'Islets of Langerhans Transplantation', 'Male', 'Pancreas', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Time Factors'] | 1,341,913 | [['B01.050'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E05.290.625', 'E05.337.425'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Preparation for nitrocellulose membrane-poly (vinyl alcohol)-ionic imprinting and its application to determine trace copper by room temperature phosphorimetry. | Nitrocellulose membrane-poly (vinyl alcohol)-ionic imprinting (NCM-PVA-I-I) was prepared using Cu2+ as template. The cavity in NCM-PVA-I-I matched Cu2+ very well and the selectivity was high. Cu2+ entered the cavity and then could form ionic association ([Cu2+] x [(Fin-)2]) with the anion of fluorescein (Fin-) outside ... | ['Collodion', 'Copper', 'Ions', 'Polyvinyl Alcohol', 'Temperature'] | 17,397,651 | [['D25.720.099.500.439', 'J01.637.051.720.099.500.439'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D01.248.497'], ['D02.033.750', 'D02.455.326.271.884.533.532', 'D05.750.716.721.616', 'D25.720.716.721.616', 'J01.637.051.720.716.721.616'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.71... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Microscale control of cell contact and spacing via three-component surface patterning. | The complexity of micropatterned cell constructs has been limited by difficulties in patterning more than two surface components on a culture substrate. Photolithography using multiple aligned masks is well established for generalized multicomponent patterning, but is often too harsh for biomolecules. We report a two-m... | ['Animals', 'Biocompatible Materials', 'Biophysical Phenomena', 'Biophysics', 'Cell Communication', 'Chemistry, Physical', 'Extracellular Matrix', 'Fibroblasts', 'Hepatocytes', 'Materials Testing', 'Mice', 'Microscopy, Fluorescence', 'Microscopy, Phase-Contrast', 'NIH 3T3 Cells', 'Polyethylene Glycols', 'Surface Proper... | 17,243,746 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['G04.085'], ['H01.181.529'], ['A11.284.295.310'], ['A11.329.228'], ['A11.436.348'], ['E05.570'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.458', 'E05.595.458'], ['E01.370.350.515.513.569',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Neurons induce contractions in myotubes containing only muscular dysgenic nuclei. | Muscular dysgenic (mdg/mdg) myotubes cultured alone do not contract. Glucosephosphate isomerase (GPI-1) isozymes were analyzed to determine the final genotype of cultured dysgenic (mdg/mdg, gpi-1a/a) myotubes to which normal embryonic spinal cord and limb cells (CBA/J +/+, gpi-1b/b) had been added. Although both myobla... | ['Animals', 'Cells, Cultured', 'Genotype', 'Glucose-6-Phosphate Isomerase', 'In Vitro Techniques', 'Isoenzymes', 'Mice', 'Muscle Contraction', 'Muscles', 'Neuromuscular Diseases', 'Neurons', 'Spinal Cord', 'Synapses'] | 6,708,966 | [['B01.050'], ['A11.251'], ['G05.380'], ['D08.811.399.475.200.350'], ['E05.481'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['G11.427.494'], ['A02.633', 'A10.690'], ['C10.668'], ['A08.675', 'A11.671'], ['A08.186.854'], ['A08.850', 'A11.284.149.165.420.780']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1. | A 48-year-old woman was infected with a vpr-defective human immunodeficiency virus (HIV)-1 molecular clone. Seroconversion was markedly delayed, and without treatment she had durably suppressed viremia and normal T-cell levels. Neutralizing antibody and CD8+ T-cell immune responses against HIV-1 were unremarkable. Vira... | ['AIDS Vaccines', 'B-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cloning, Molecular', 'Female', 'Gene Products, vpr', 'HIV Infections', 'HIV-1', 'Humans', 'Middle Aged', 'Vaccination', 'Vaccines, Attenuated'] | 29,878,133 | [['D20.215.894.899.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['E05.393.220'], ['D12.776.964.925.984.430'], ['C01.221.250.875', 'C01.221... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of annual dosing with ivermectin on progression of onchocercal visual field loss. | Reported are the results of a randomized, double-masked, placebo-controlled trial of annual ivermectin dosing in 34 rural communities, Kaduna State, northern Nigeria, where guinea savanna onchocerciasis is mesoendemic. A total of 939 individuals underwent Friedmann field analysis at the first examination and saw at lea... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Double-Blind Method', 'Female', 'Filaricides', 'Follow-Up Studies', 'Humans', 'Incidence', 'Ivermectin', 'Male', 'Middle Aged', 'Nigeria', 'Onchocerciasis, Ocular', 'Rural Health', 'Visual Fields'] | 9,277,010 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.954.122.250.075.080.275'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site. | The regulation of the 2-oxoglutarate dehydrogenase complex is central to intramitochondrial energy metabolism. In the present study, the active full-length E1 subunit of the human complex has been expressed and shown to be regulated by Ca2+, adenine nucleotides and NADH, with NADH exerting a major influence on the K0.5... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Calcium', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Ketoglutarate Dehydrogenase Complex', 'Ketoglutaric Acids', 'Kinetics', 'Molecular Sequence Data', 'Molecular Structure', 'Myocardium', 'Protein Binding', 'Protein Subunits', 'Species Specificity', 'Swin... | 24,495,017 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.500.562.468', 'D08.811.600.465', 'D08.811.682.657.350.750'], ['D02.241.081.337.351.502', 'D02.241.755.465'], ['G01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Flow-dependent transport processes: filtration, absorption, secretion. | To define aspects common to different flow-dependent renal transport processes, four examples of such transport processes are considered: glomerular filtration, distal potassium secretion, ascending limb sodium absorption, and proximal fluid absorption. For each example the phenomenon of flow dependence is documented a... | ['Animals', 'Biological Transport', 'Blood Proteins', 'Glomerular Filtration Rate', 'Humans', 'Kidney', 'Kidney Tubules', 'Nephrons', 'Regional Blood Flow', 'Sodium'] | 7,091,365 | [['B01.050'], ['G03.143'], ['D12.776.124'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A05.810.453.736.560'], ['A05.810.453.736'], ['G09.330.100.780'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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