Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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A comparison of the expressive communication skills of triplet, twin and singleton children. | Few studies have focused on the language acquisition of higher multiple birth sets. In this study, the communication skills of 51 triplet children are described. The measures used were: mean length of utterance; type-token ratio; conversational acts; phoneme repertoire; and number of different types of phonological pro... | ['Child, Preschool', 'Communication', 'Female', 'Humans', 'Language Development', 'Language Disorders', 'Linguistics', 'Male', 'Mother-Child Relations', 'Speech Disorders', 'Triplets', 'Twins'] | 9,474,285 | [['M01.060.406.448'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.525.200.310'], ['C10.597.606.150.500', 'C23.888.592.604.150.500'], ['L01.559.598'], ['F01.829.263.370.290.170'], ['C10.597.606.150.500.800', 'C23.888.592.604.150.500.800'], ['M01.438.768'], ['M01.438.873']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Breast cancer risk following radiotherapy for Hodgkin lymphoma: modification by other risk factors. | The importance of genetic and other risk factors in the development of breast cancer after radiotherapy (RT) for Hodgkin lymphoma (HL) has not been determined. We analyzed data from a breast cancer case-control study (105 patients, 266 control subjects) conducted among 3 817 survivors of HL diagnosed at age 30 years or... | ['Adult', 'Breast Neoplasms', 'Female', 'Hodgkin Disease', 'Humans', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Neoplasms, Second Primary', 'Odds Ratio', 'Radiotherapy Dosage', 'Retrospective Studies', 'Risk Factors'] | 16,051,739 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.682', 'C26.733.476', 'G01.750.748.500.476'], ['C04.692'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590',... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Emotional reactivity to daily life stress in psychosis and affective disorder: an experience sampling study. | OBJECTIVE: To investigate the emotional reactivity to small disturbances in daily life in patients with non-affective psychosis (NAP), bipolar disorder (BD) and major depression [major depressive disorder (MDD)].METHOD: Forty-two patients with NAP, 38 with BD, 46 with MDD, and 49 healthy controls were studied with the ... | ['Activities of Daily Living', 'Adult', 'Aged', 'Bipolar Disorder', 'Depressive Disorder', 'Emotions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychotic Disorders', 'Regression Analysis', 'Risk Factors', 'Stress, Psychological'] | 12,534,438 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['F03.600.300'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.700.675'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Regional differences between people who inject drugs in an HIV prevention trial integrating treatment and prevention (HPTN 074): a baseline analysis. | INTRODUCTION: People who inject drugs (PWID) experience high HIV incidence and face significant barriers to engagement in HIV care and substance use treatment. Strategies for HIV treatment as prevention and substance use treatment present unique challenges in PWID that may vary regionally. Understanding differences in ... | ['Adolescent', 'Adult', 'CD4 Lymphocyte Count', 'Cohort Studies', 'Female', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Sexual Behavior', 'Substance Abuse, Intravenous', 'Viral Load', 'Young Adult'] | 30,350,406 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.85... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surfactant bilayers maintain transmembrane protein activity. | In vitro studies of membrane proteins are of interest only if their structure and function are significantly preserved. One approach is to insert them into the lipid bilayers of highly viscous cubic phases rendering the insertion and manipulation of proteins difficult. Less viscous lipid sponge phases are sometimes use... | ['Bacteriorhodopsins', 'Biomimetic Materials', 'Ethers', 'Glucosides', 'Lipid Bilayers', 'Membrane Proteins', 'Micelles', 'Microscopy, Electron', 'Phase Transition', 'Polyethylene Glycols', 'Sarcoplasmic Reticulum Calcium-Transporting ATPases', 'Surface-Active Agents', 'Temperature', 'Viscosity', 'Water'] | 25,185,548 | [['D12.776.090.200', 'D12.776.157.530.450.250.875.249', 'D12.776.543.585.450.250.875.249', 'D12.776.752.812.249'], ['J01.637.087'], ['D02.355'], ['D09.408.348'], ['D10.570.510', 'J01.637.087.500.510'], ['D12.776.543'], ['D05.374', 'D26.255.560'], ['E01.370.350.515.402', 'E05.595.402'], ['G01.645', 'G02.734'], ['D02.033... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Clinical Significance of Late Phase of Lung Perfusion Blood Volume (Lung Perfusion Blood Volume) Quantified by Dual-Energy Computed Tomography in Patients With Pulmonary Thromboembolism. | PURPOSE: Using dual-energy computed tomography (DECT), we quantified the lung perfusion blood volume (PBV) in the late phase, which may reflect both the pulmonary artery and systemic collateral flow. We then investigated the clinical significance of late-phase lung PBV values.MATERIALS AND METHODS: We retrospectively s... | ['Aged', 'Blood Volume', 'Female', 'Humans', 'Lung', 'Male', 'Pulmonary Artery', 'Pulmonary Embolism', 'Radiographic Image Interpretation, Computer-Assisted', 'Radiography, Dual-Energy Scanned Projection', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 27,846,051 | [['M01.060.116.100'], ['G09.188.130', 'G09.330.380.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['A07.015.114.715'], ['C08.381.746', 'C14.907.355.350.700'], ['E01.158.600.680', 'E01.370.350.350.700', 'E01.370.350.700.705', 'L01.313.500.750.100.158.600.680'], ['E01.370.350.600.350.700.700', 'E01.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Neighborhood disadvantage, network social capital, and depressive symptoms. | Research on why neighborhood disadvantage matters for health focuses on the capacity of neighborhoods to regulate residents' behavior through informal social control. The authors extend this research by conducting a multilevel analysis of data from a 1995 telephone survey of 497 residents of 32 neighborhoods in a U.S. ... | ['Adult', 'Depression', 'Female', 'Humans', 'Linear Models', 'Male', 'Residence Characteristics', 'Social Control, Informal', 'Social Environment', 'Social Support', 'Surveys and Questionnaires', 'United States'] | 21,362,612 | [['M01.060.116'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['N01.224.791', 'N06.850.505.400.800'], ['I01.880.630'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pilot study of expanded carrier screening for 11 recessive diseases in China: results from 10,476 ethnically diverse couples. | Expanded carrier screening (ECS) has been demonstrated to increase the detection rate of carriers compared with traditional tests. The aim of this study was to assess the potential value of ECS for clinical application in Southern China, a region with high prevalence of thalassemia and with diverse ethnic groups, and t... | ['Adult', 'Ethnic Groups', 'Female', 'Gene Frequency', 'Genes, Recessive', 'Genetic Carrier Screening', 'Humans', 'Male', 'Pilot Projects', 'Sample Size'] | 30,275,481 | [['M01.060.116'], ['M01.686.754', 'N01.224.317'], ['G05.330'], ['G05.360.340.024.340.415', 'G05.420.325'], ['E01.370.225.562.250', 'E05.200.562.250', 'E05.393.435.250', 'N02.421.308.200', 'N02.421.726.233.221.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association between renal function, erectile function and coronary artery disease: detection with coronary angiography. | PURPOSE: Many patients admitted for acute myocardial infarction (AMI) have chronic renal insufficiency and erectile dysfunction (ED). This study aimed to evaluate the relationship between ED and the glomerular filtration rate (GFR) in patients with coronary artery disease.MATERIALS AND METHODS: We studied 183 patients ... | ['Adult', 'Aged', 'Coronary Angiography', 'Coronary Artery Disease', 'Coronary Occlusion', 'Erectile Dysfunction', 'Glomerular Filtration Rate', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Renal Insufficiency, Chronic', 'Risk Factors', 'Severity of Illness Index'] | 25,598,940 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['C12.294.644.486', 'F03.835.400'], ['E01.370.390.400.300', 'G08... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bayesian variable selection in the accelerated failure time model with an application to the surveillance, epidemiology, and end results breast cancer data. | Accelerated failure time model is a popular model to analyze censored time-to-event data. Analysis of this model without assuming any parametric distribution for the model error is challenging, and the model complexity is enhanced in the presence of large number of covariates. We developed a nonparametric Bayesian meth... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Bayes Theorem', 'Breast Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Models, Statistical', 'Monte Carlo Method', 'Population Surveillance', 'Prognosis', 'SEER Program', 'Survival Analysis', 'Young Adult'] | 28,034,170 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Quantification of P-selectin expression after renal ischemia and reperfusion. | Neutrophils are important in ischemia and reperfusion injury. Multiple factors may be responsible for the adhesion of granulocytes to endothelial cells. P-selectin is a carbohydrate-binding glycoprotein that is stored preformed in endothelial cells as Weibel-Palade bodies. This preformation implies a very early role of... | ['Animals', 'Ischemia', 'Kidney', 'Kidney Tubular Necrosis, Acute', 'Male', 'Mice', 'Mice, Inbred C57BL', 'P-Selectin', 'Reperfusion Injury', 'Time Factors', 'Up-Regulation'] | 9,247,223 | [['B01.050'], ['C23.550.513'], ['A05.810.453'], ['C12.777.419.780.050.500', 'C13.351.968.419.780.050.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.395.550.200.700.775', 'D12.776.395.550.625.905', 'D12.776.503.843.775', '... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Variability of Executive Function Performance in Preschoolers with Developmental Language Disorder. | Although results vary across individual studies, a large body of evidence suggests that children with developmental language disorder (DLD) have domain-general deficits in executive function compared with peers with typically developing language. Poorer performance for children with DLD has been reported on verbal and ... | ['Attention', 'Child, Preschool', 'Comorbidity', 'Executive Function', 'Female', 'Humans', 'Inhibition, Psychological', 'Language Development Disorders', 'Male', 'Memory, Short-Term', 'Neuropsychological Tests', 'Verbal Learning'] | 31,311,051 | [['F02.830.104.214'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['C10.597.606.150.500.550', 'C23.888.592.604.150.500.550'], ['F02.463.425.540.407'], ['F04.711.513'], ['F02.463.425.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Proteoglycans synthesized by gingival fibroblasts derived from human donors of different ages. | The proteoglycans synthesized by fibroblasts derived from human donors of ages ranging from 12 years to 68 years have been studied. In addition, the in vitro proliferation rates of the various cell strains were studied and demonstrated that increasing donor age correlated with a decrease in proliferative activity. The ... | ['Adult', 'Aged', 'Aging', 'Cell Division', 'Cells, Cultured', 'Child', 'Chromatography, Gel', 'Fibroblasts', 'Gingiva', 'Glycosaminoglycans', 'Humans', 'Middle Aged', 'Proteoglycans', 'Sulfates', 'Sulfur Radioisotopes'] | 3,944,197 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['M01.060.406'], ['E05.196.181.400.250'], ['A11.329.228'], ['A14.549.167.646.480'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D09.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Work ability and quality of life of Brazilian industrial workers]. | The scope of this study was to evaluate the quality of life and work ability of industrial workers by means of self-perception questionnaires. 100 industrial production line workers on the night shift participated in this study. Authorized Brazilian translations of the Work Ability Index (WAI) and the Abbreviated World... | ['Adult', 'Brazil', 'Female', 'Humans', 'Industry', 'Male', 'Occupational Health', 'Quality of Life', 'Surveys and Questionnaires', 'Work Capacity Evaluation'] | 22,699,653 | [['M01.060.116'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['N01.400.525'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E01.370.400.925']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Human platelet-derived growth factor. Purification and resolution into two active protein fractions. | Human platelets secrete a factor that stimulates cultured human cells to initiate DNA synthesis and to divide. This human platelet-derived growth factor (PDGF) has been purified congruent to 100,000-fold into two equally active homogeneous fractions, PDGF I (Mr congruent to 31,000) and PDGF II (Mr congruent to 28,000).... | ['Amino Acids', 'Blood Platelets', 'Carbohydrates', 'Growth Substances', 'Humans', 'Molecular Weight', 'Peptides', 'Platelet-Derived Growth Factor'] | 7,263,691 | [['D12.125'], ['A11.118.188', 'A15.145.229.188'], ['D09'], ['D27.505.696.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.494'], ['D12.644'], ['D12.644.276.910', 'D12.776.124.625', 'D12.776.467.910', 'D23.529.910']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antifibrotic action of interleukin-1 receptor antagonist in lapine monoarticular arthritis. | OBJECTIVE: To determine if the administration of interleukin-1 receptor antagonist (IL-1ra) to animals with established antigen induced arthritis had any beneficial effects on the synovitis and cartilage destruction.METHODS: Antigen induced arthritis was induced in New Zealand White rabbits, and after two weeks IL-1ra ... | ['Animals', 'Arthritis, Experimental', 'Cartilage, Articular', 'Collagen', 'Female', 'Fibrosis', 'Interleukin 1 Receptor Antagonist Protein', 'Knee Joint', 'Leukocyte Count', 'Proteoglycans', 'Rabbits', 'Receptors, Interleukin-1', 'Recombinant Proteins', 'Sialoglycoproteins', 'Synovitis'] | 7,668,904 | [['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['A02.165.407.150', 'A02.835.583.192'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C23.550.355'], ['D12.644.276.374.460', 'D12.776.467.374.460', 'D23.529.374.460'], ['A02.835.583.475'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.1... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An Erwinia amylovora yjeK mutant exhibits reduced virulence, increased chemical sensitivity and numerous environmentally dependent proteomic alterations. | The Gram-negative bacterium Erwinia amylovora causes fire blight, an economically important disease of apples and pears. Elongation factor P (EF-P) is a highly conserved protein that stimulates the formation of the first peptide bond of certain proteins and facilitates the translation of certain proteins, including tho... | ['Bacterial Proteins', 'Erwinia amylovora', 'Malus', 'Peptide Elongation Factors', 'Plant Diseases', 'Proteomics', 'Pyrus', 'Virulence'] | 29,232,043 | [['D12.776.097'], ['B03.440.450.425.300.050', 'B03.660.250.150.175.050'], ['B01.650.940.800.575.912.250.859.937.500.444'], ['D12.776.835.700'], ['G15.610'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['B01.650.940.800.575.912.250.859.937.500.699'], ['G06.930']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling Glucose Transport From Systemic Circulation to Sweat. | Sweat sensing may provide a noninvasive means of estimating blood biomarker levels if a number of technological hurdles can be overcome. This report describes progress on a physiologically based transport model relating sweat glucose and key electrolyte concentrations to those in blood. Iontophoretically stimulated swe... | ['Adult', 'Biological Transport', 'Blood Glucose', 'Calibration', 'Electrolytes', 'Female', 'Glucose', 'Glucose Transport Proteins, Facilitative', 'Humans', 'Male', 'Skin', 'Sweat', 'Young Adult'] | 30,273,561 | [['M01.060.116'], ['G03.143'], ['D09.947.875.359.448.500'], ['E05.978.155'], ['D01.248'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500', 'D12.776.157.530.937.563', 'D12.776.543.585.500.500', 'D12.776.543.585.937.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A17.815'], ['A12.200.849'], ['M01.060.116.81... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Faux review. A report on the zombie outbreak of 2009: how mathematics can save us (no, really). | An outbreak of zombification wreaked havoc recently in Canada and the rest of the world. Mathematical models were created to establish the speed of zombie infection and evaluate potential scenarios for intervention, mainly because mathematicians don't have anything better to do with their time. We review the developmen... | ['Models, Statistical', 'Wit and Humor as Topic'] | 19,969,573 | [['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['F01.100.960', 'K01.517.946']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Splenic infarction. Ergotism induced by ritonavir?]. | Ergotism is a clinical condition known since old times and whose main characteristics are ischemia and even limb gangrene. Some drugs have the capacity of interacting with small amounts of ergotamine or its derivatives producing ergotism as a side effect. This is the case of ritonavir, a widely used anti-HIV drug. Here... | ['Adult', 'Drug Interactions', 'Ergotamine', 'Ergotism', 'HIV Infections', 'HIV Protease Inhibitors', 'Humans', 'Male', 'Ritonavir', 'Splenic Infarction', 'Tomography, X-Ray Computed', 'Vasoconstrictor Agents'] | 23,241,290 | [['M01.060.116'], ['G07.690.773.968'], ['D03.132.327.412.400', 'D03.633.400.562.500'], ['C25.723.680.262'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['D27.505.519.389.745.900.500', 'D27.505.954.122.388.077.088.420'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors for the development of abdominal abscess following operation for perforated appendicitis in children: a multicenter case-control study. | HYPOTHESIS: The morbidity following treatment for perforated appendicitis in children is significant, with intra-abdominal abscess being one of the more serious complications. This can lead to prolonged hospitalizations and antibiotic administration, multiple computed tomographic scans, and invasive procedures. The pur... | ['Abdominal Abscess', 'Adolescent', 'Appendectomy', 'Appendicitis', 'Child', 'Child, Preschool', 'Confidence Intervals', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant', 'Length of Stay', 'Male', 'Postoperative Complications', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Sex Characteristics'] | 17,372,047 | [['C01.830.025.020'], ['M01.060.057'], ['E04.210.078'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anatomic suitability for present and next generation transcatheter aortic valve prostheses: evidence for a complementary multidevice approach to treatment. | OBJECTIVES: This study sought to assess the proportion of patients anatomically suitable for transcatheter aortic valve implantation by multiple access approaches.BACKGROUND: The devices currently in mainstream use for transcatheter treatment of severe aortic stenosis are those of Edwards (Edwards Lifesciences, Nyon, S... | ['Aged', 'Aged, 80 and over', 'Angiography', 'Aorta', 'Aortic Valve', 'Aortic Valve Stenosis', 'Cardiac Catheterization', 'Echocardiography, Transesophageal', 'England', 'Femoral Artery', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Humans', 'Patient Selection', 'Predictive Value of Tests', 'Prospe... | 20,723,859 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A07.015.114.056'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['Z01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The SMART personalised self-management system for congestive heart failure: results of a realist evaluation. | BACKGROUND: Technology has the potential to provide support for self-management to people with congestive heart failure (CHF). This paper describes the results of a realist evaluation of the SMART Personalised Self-Management System (PSMS) for CHF.METHODS: The PSMS was used, at home, by seven people with CHF. Data desc... | ['Health Knowledge, Attitudes, Practice', 'Heart Failure', 'Humans', 'Interviews as Topic', 'Microcomputers', 'Mobile Applications', 'Monitoring, Ambulatory', 'Patient-Centered Care', 'Program Development', 'Program Evaluation', 'Qualitative Research', 'Self Care'] | 25,421,307 | [['F01.100.150.500', 'N05.300.150.410'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['L01.224.230.260.550'], ['L01.224.900.685'], ['E01.370.520.500'], ['N04.590.233.727.407'], ['N04.452.760'], ['E05.337.820', 'N... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
A comparison between conductive and infrared devices for measuring mean skin temperature at rest, during exercise in the heat, and recovery. | PURPOSE: Skin temperature assessment has historically been undertaken with conductive devices affixed to the skin. With the development of technology, infrared devices are increasingly utilised in the measurement of skin temperature. Therefore, our purpose was to evaluate the agreement between four skin temperature dev... | ['Adult', 'Exercise', 'Hot Temperature', 'Humans', 'Infrared Rays', 'Male', 'Skin Temperature', 'Thermometers'] | 25,659,140 | [['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Glycidol, a Valuable Substrate for the Synthesis of Monoalkyl Glyceryl Ethers: A Simplified Life Cycle Approach. | The disposal of any waste by recovering it within the production plant represents the ultimate goal of every biorefinery. In this scenario, the selective preparation of monoalkyl glyceryl ethers (MAGEs) starting from glycidol, obtained as byproduct in the epichlorohydrin production plant, represents a very promising st... | ['Catalysis', 'Epoxy Compounds', 'Glyceryl Ethers', 'Propanols'] | 28,376,258 | [['G02.130'], ['D02.355.291.411'], ['D02.033.800.875.875', 'D02.355.460'], ['D02.033.755']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The heterogeneity of human IgE exemplified by the passive transfer of D2O sensitivity. | Basophil responsiveness to histamine-releasing factors (HRF) is limited to cells from atopic donors; this response can be transferred passively to non-reactive basophils by IgE molecules from the sera of donors who are intrinsically responsive to HRF. Deuterium oxide (D2O) also causes mediator release from the basophil... | ['Antigens, Differentiation, B-Lymphocyte', 'Basophils', 'Deuterium', 'Deuterium Oxide', 'Histamine Release', 'Humans', 'Immunization, Passive', 'Immunoglobulin E', 'Receptors, Fc', 'Receptors, IgE', 'Water'] | 1,708,690 | [['D23.050.301.264.051', 'D23.101.100.150'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['D01.045.250.875.200', 'D01.248.497.158.459.650.200', 'D01.268.406.500.250', 'D01.362.340.500.250'], ['G12.350'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The biologic half-life of heparin. | Half-lives (t1/2s) varying from 23 min to 2.48 hr have been reported for heparin. It is shown that much of the discrepancy between authors can be attributed to methods used to analyze data. It is suggested that three terms should be carefully used, the t1/2 of bioassayed heparin concentration, the t1/2 of the extension... | ['Biological Assay', 'Blood Coagulation', 'Half-Life', 'Heparin', 'Humans', 'Methods'] | 761,447 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cells bearing Fc receptors in human malignant solid tumours. | Fc-receptor-bearing cells forming EA rosettes with antibody-coated human erythrocytes (Ripley) were studied in cell suspensions and in purified preparations of mononuclear cells (MC) from 20 human malignant tumours. The EA rosettes were studied in preparations made by cytocentrifugation and the rosette-forming cells id... | ['Bronchial Neoplasms', 'Cells, Cultured', 'Gastrointestinal Neoplasms', 'Humans', 'Lymphocytes', 'Neoplasms', 'Receptors, Fc', 'Rosette Formation'] | 7,059,470 | [['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['A11.251'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['C04'], ['D12.776.543.750.705.871'], ['E01.370.225.812.706', 'E05.2... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fetal macrosomia--animal models. | Macrosomia is characteristic of the infant whose mother has undiagnosed diabetes mellitus during pregnancy or whose diabetes has been inadequately controlled. Animal models of diabetes have included effects of pancreatectomy or beta-cell destruction by chemical agents. Maternal effects have been variable as have been ... | ['Animals', 'Birth Weight', 'Diabetes Mellitus, Experimental', 'Disease Models, Animal', 'Female', 'Fetus', 'Gestational Age', 'Haplorhini', 'Humans', 'Infant, Newborn', 'Insulin', 'Liver', 'Macaca mulatta', 'Organ Size', 'Pregnancy', 'Pregnancy in Diabetics', 'Rats'] | 6,771,112 | [['B01.050'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Seasonal dynamics of influenza in Brazil: the latitude effect. | BACKGROUND: Influenza is a global transmissible disease. Its dynamics is far better understood in temperate climates than in the tropics. We aim to close this knowledge gap between tropical and temperate regions by showing how the influenza seasonality evolves in Brazil, a tropical country that encompasses a wide range... | ['Brazil', 'Ecology', 'Geography', 'Humans', 'Incidence', 'Influenza, Human', 'Respiratory Distress Syndrome', 'Seasons', 'Wavelet Analysis'] | 30,587,159 | [['Z01.107.757.176'], ['H01.158.273.248', 'H01.277.249'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['C08.381.840', 'C08.618.84... | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
[Detection of anti-H-2-antibody-induced cytolysis by ATP measurement (author's transl)]. | Measurement of intracellular ATP content by the luciferin-luciferase photometric reaction appears to be an extremely sensitive method for detecting complement dependent cytotoxicity (DCD) mediated by antibodies directed against H-2 antigens. Within the 15 min following the addition of complement, a considerable loss of... | ['Adenosine Triphosphate', 'Animals', 'Cytotoxicity, Immunologic', 'H-2 Antigens', 'Immune Sera', 'Male', 'Methods', 'Mice', 'Spleen'] | 496,404 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sustainable management of a coupled groundwater-agriculture hydrosystem using multi-criteria simulation based optimisation. | In this paper we present a new simulation-based integrated water management tool for sustainable water resources management in arid coastal environments. This tool delivers optimised groundwater withdrawal scenarios considering saltwater intrusion as a result of agricultural and municipal water abstraction. It also yie... | ['Agriculture', 'Algorithms', 'Biomass', 'Computer Simulation', 'Groundwater', 'Neural Networks, Computer', 'Salinity', 'Water Movements', 'Water Supply'] | 23,202,577 | [['J01.040'], ['G17.035', 'L01.224.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['L01.224.160'], ['G01.311.355'], ['G17.485', 'L01.224.050.375.605'], ['G02.640.500'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['J01.293.821.500']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Agreement between arterial and central venous values for pH, bicarbonate, base excess, and lactate. | OBJECTIVE: This study aimed to determine the extent of agreement between central venous and arterial values for pH, bicarbonate, base excess, and lactate in a group of intensive care unit (ICU) patients.METHODS: A prospective study of a convenience sample of patients deemed by their treating doctor to require blood gas... | ['Acid-Base Imbalance', 'Arteries', 'Bicarbonates', 'Blood Gas Analysis', 'Critical Care', 'Emergency Medical Services', 'Humans', 'Hydrogen-Ion Concentration', 'Lactates', 'Prospective Studies', 'Reference Values', 'Veins'] | 16,858,095 | [['C18.452.076'], ['A07.015.114'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E02.760.190', 'N02.421.585.190'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D02.241.511.459'], ['E05.318.372.500.750.... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Strikes and startles of northern pike (Esox lucius): a comparison of muscle activity and kinematics between S-start behaviors. | S-starts are a major class of fast-start behaviors that serve diverse locomotor functions in fishes, playing roles in both feeding strike and escape startle events. While movement patterns are similar during strike and startle, their motor control mechanisms have not been compared. To investigate heterogeneity in S-sta... | ['Analysis of Variance', 'Animals', 'Biomechanical Phenomena', 'Electromyography', 'Esocidae', 'Jaw', 'Motor Activity', 'Muscle, Skeletal', 'Predatory Behavior', 'Reflex, Startle', 'Video Recording'] | 14,691,101 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.493.385.300'], ['A02.835.232.781.324.502', 'A14.521'], ['F01.145.632', 'G11.427.410.698'], ['A02.633.567', 'A10.690.552.500'], ['F01.145.113.111.600'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias. | Platelets release microparticles (PMP) upon activation. Elevated levels of PMP were observed in patients with immune thrombocytopenic purpura (ITP), sometimes associated with a syndrome resembling transient ischemic attack (TIA), suggesting a thrombogenic potential for PMP. To determine if this association applies to T... | ['Adult', 'Aged', 'Alzheimer Disease', 'Blood Platelets', 'Cerebral Infarction', 'Dementia, Multi-Infarct', 'Female', 'Humans', 'Ischemic Attack, Transient', 'Male', 'Middle Aged', 'Nifedipine', 'Particle Size'] | 8,303,669 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A11.118.188', 'A15.145.229.188'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['C10.228.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Exteriorization of thoracic duct lymph. Theoretical considerations and an experimental model. | Successful manipulation of the immune response will ultimately provide the answers for controlling homograft rejection, reversing autoimmune states, and quite possibly for curing carcinoma and other malignant neoplasms. During the past decade, many new drugs and techniques have been developed that alter the immune stat... | ['Animals', 'Antibody Formation', 'Antigen-Antibody Reactions', 'Catheterization', 'Dogs', 'Graft Rejection', 'Hypersensitivity, Delayed', 'Immunity, Cellular', 'Immunosuppression', 'Jugular Veins', 'Lymph', 'Lymphocyte Activation', 'Models, Biological', 'T-Lymphocytes', 'Thoracic Duct', 'Transplantation, Homologous'] | 1,081,872 | [['B01.050'], ['G12.450.050.370.250'], ['G12.122'], ['E02.148', 'E05.157'], ['B01.050.150.900.649.313.750.250.216.200'], ['G12.875.545.328'], ['C20.543.418'], ['G12.450.050.400'], ['E02.095.465.425.450', 'E05.478.610'], ['A07.015.908.498'], ['A12.207.270.606', 'A15.382.520.150'], ['E01.370.225.812.482', 'E05.200.812.48... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Anatomical relationship of the ethmoid-sphenoid areas to the optic canal and the internal carotid artery]. | The anatomical relationships and morphologic features of the optic canal and the internal carotid artery to the lateral wall of the most posterior ethmoidal cell and the sphenoid sinus in 100 half-skulls swan middle-saggitally were investigated. The results showed: (1) The whole optic canals neighboured with the most e... | ['Anthropometry', 'Carotid Artery, Internal', 'Endoscopy', 'Ethmoid Sinus', 'Humans', 'Optic Nerve', 'Sphenoid Sinus'] | 7,654,422 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['A07.015.114.186.200.230'], ['E01.370.388.250', 'E04.502.250'], ['A04.531.621.267'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.120.680'], ['A04.531.621.827']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibitors of "spontaneous" platelet aggregation in whole blood. | In vitro 'spontaneous' platelet aggregation has been studied in whole blood. The spectrum of activity of materials known to influence platelet aggregation in platelet-rich plasma proved different in whole blood. Thus dipyridamole and one of its analogues SH1242 had a striking effect in whole blood whilst aspirin, chlor... | ['Aspirin', 'Blood Physiological Phenomena', 'Chlorpromazine', 'Dipyridamole', 'Drug Interactions', 'Female', 'Humans', 'In Vitro Techniques', 'Male', 'Platelet Aggregation'] | 4,091,879 | [['D02.455.426.559.389.657.410.595.176'], ['G09.188'], ['D02.886.369.198', 'D03.633.300.783.198'], ['D03.383.742.175'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G09.188.370.687', 'G09.188.390.600.640']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Research Trends of Macrophage Polarization: A Bibliometric Analysis. | Background: Macrophage polarization is involved in the development of many diseases such as obesity, diabetes, and cancer. This study aimed to understand the trends and hotspots of macrophage polarization research.Methods: We searched through the Web of Science Core Collection database to obtain original articles in th... | ['Bibliometrics', 'Biomedical Research', 'Cell Polarity', 'Efficiency', 'Humans', 'Macrophages'] | 30,539,910 | [['L01.178.682.099.325', 'L01.453.183.291'], ['H01.770.644.145'], ['G04.250'], ['F02.784.692.351', 'N04.452.209'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397']] | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Phasmid P4: manipulation of plasmid copy number and induction from the integrated state. | "Phasmid" P4 is unusual in that it is capable of (i) temperate, (ii) lytic, helper-dependent, and (iii) plasmid modes of propagation. In this report we characterize most of the known P4 genetic functions as to their essential or nonessential roles in the stable maintenance of plasmid P4 vir1 (pP4 vir1 (pP4 vir1). We al... | ['Coliphages', 'DNA Replication', 'Escherichia coli', 'Genes, Regulator', 'Genes, Viral', 'Lysogeny', 'Mutation', 'Plasmids', 'Recombination, Genetic', 'Temperature', 'Virus Activation', 'Virus Replication'] | 6,370,957 | [['B04.123.205'], ['G02.111.225', 'G05.226'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.425'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G05.935.500', 'G06.920.877.500'], ['G05.365.590'], ['G05.360.600'], ['G05.728'], ['G01.906.595', 'G1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Children's hospice care. | Facing the inevitable death of a child is a difficult reality for many parents and health care providers as well. Children's Hospice International offers a variety of information and education services to support the provision of children's hospice care. | ['Bereavement', 'Child, Preschool', 'Education, Nursing, Continuing', 'Family', 'Hospices', 'Humans', 'International Agencies', 'Male', 'Organizational Objectives', 'Social Support'] | 2,392,342 | [['F01.470.142'], ['M01.060.406.448'], ['I02.358.212.450', 'I02.358.462.399'], ['F01.829.263', 'I01.880.853.150'], ['N02.278.421.556.185', 'N02.421.143.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['N04.452.615'], ['I01.880.853.500.600']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Undifferentiated carcinoma with lymphoid stroma of the parotid gland. | A rare undifferentiated carcinoma with lymphoid stroma (UCLS) of the parotid gland is described in a white Turkish patient. The raised serum IgG to Epstein-Barr virus capsid antigen suggests a causal relationship between Epstein-Barr virus and this type of salivary gland carcinoma. Some clinical features are briefly re... | ['Carcinoma', 'Female', 'Herpesviridae Infections', 'Herpesvirus 4, Human', 'Humans', 'Middle Aged', 'Parotid Neoplasms', 'Tumor Virus Infections'] | 8,289,015 | [['C04.557.470.200'], ['C01.925.256.466'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770', 'C07.465.815.718.589'], ['C01.925.928']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Elevated circulating P-selectin in insulin dependent diabetes mellitus. | Based on findings that showed increased P-selectin expression on platelets and on choroidal microvessels of patients with insulin dependent diabetes mellitus (IDDM), we hypothesized that also plasma concentrations of circulating (c)P-selectin would be increased in these patients. The aim of this study was to compare th... | ['Adolescent', 'Adult', 'Aged', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Insulin', 'Male', 'Middle Aged', 'P-Selectin', 'Prospective Studies', 'Smoking', 'von Willebrand Factor'] | 8,883,265 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['M01.060.116.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
TSLP regulates eotaxin-1 production by nasal epithelial cells from patients with eosinophilic CRSwNP. | BACKGROUND: Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by Th2-skewed inflammation with eosinophilic infiltration. Thymic stromal lymphopoietin (TSLP) promotes the development of allergic inflammation. Although increased TSLP is found in eCRSwNP, little is known about whether TSLP r... | ['Adult', 'Benzamides', 'Blotting, Western', 'Chemokine CCL11', 'Chronic Disease', 'Cytokines', 'Eosinophilia', 'Epithelial Cells', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Nasal Mucosa', 'Nasal Polyps', 'Phosphorylation', 'Pyrimidines', 'Real-Time Polymerase Chain Reaction', 'Rhinitis', 'STAT3 Transcrip... | 29,911,210 | [['M01.060.116'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.644.276.374.200.110.550', 'D12.776.467.374.200.110.550', 'D23.125.300.110.550', 'D23.469.200.110.550', 'D23.529.374.200.110.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stargazin and AMPA receptor membrane expression is increased in the somatosensory cortex of Genetic Absence Epilepsy Rats from Strasbourg. | Absence-like seizures in the Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model are believed to arise in hyperexcitable somatosensory cortical neurons, however the cellular basis of this increased excitability remains unknown. We have previously shown that expression of the Transmembrane AMPA receptor Regulato... | ['Animals', 'Calcium Channels', 'Cell Membrane', 'Disease Models, Animal', 'Epilepsy', 'Genetic Predisposition to Disease', 'Neurons', 'Phenotype', 'Rats', 'Rats, Mutant Strains', 'Receptors, AMPA', 'Somatosensory Cortex'] | 21,220,022 | [['B01.050'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['A11.284.149'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.490'], ['C23.550.291.687.500', 'G05.380.355'], ['A08.675', 'A11.671'], ['G05.695'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of inorganic lead on rat brain mitochondrial respiration and energy production. | Toxicologically significant amounts of inorganic lead were added to rat brain mitochondrial preparations that did not contain EDTA or Pi. The binding of the lead to the mitochondria was measured by anodic stripping voltometry. In the presence of lead, the respiratory control ratios decreased, implying a decrease in the... | ['Adenine Nucleotides', 'Animals', 'Brain', 'Energy Metabolism', 'In Vitro Techniques', 'Lead', 'Male', 'Mitochondria', 'Oxygen Consumption', 'Phosphorylation', 'Rats'] | 7,205,261 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['B01.050'], ['A08.186.211'], ['G03.295'], ['E05.481'], ['D01.268.556.435', 'D01.552.544.435'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G03.680'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mass Spectral Character of Fentanyl Analogues. | Abstract: Objective To provide the reference for the identification of unknown fentanyl analogues by studying the characteristic ions and main fragmentation pathways of fentanyl analogues in the modes of collision induced dissociation ?CID? and electron ionization ?EI?. Methods Nine fentanyl analogues ?2, 2'-difluorofe... | ['Chemistry Techniques, Analytical', 'Chromatography, High Pressure Liquid', 'Fentanyl', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Mass Spectrometry'] | 31,135,118 | [['E05.196'], ['E05.196.181.400.300'], ['D03.383.621.265'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detailed assessment of nutritional status and eating patterns in children with gastrointestinal diseases attending an outpatients clinic and contemporary healthy controls. | BACKGROUND/OBJECTIVES: In the era of modern multidisciplinary clinical management, very little is known about the prevalence and presentation of malnutrition in children with gastrointestinal disorders (GastroD) particularly employing composite, global measures of nutritional status.SUBJECTS/METHODS: Anthropometry, bod... | ['Adolescent', 'Body Composition', 'Body Mass Index', 'Body Weight', 'Case-Control Studies', 'Celiac Disease', 'Child', 'Colitis, Ulcerative', 'Crohn Disease', 'Diet', 'Feeding Behavior', 'Female', 'Gastrointestinal Diseases', 'Hand Strength', 'Hospitalization', 'Humans', 'Male', 'Micronutrients', 'Nutrition Assessment... | 24,424,079 | [['M01.060.057'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.318.372.500.500', 'N05.715.360.330.500.500... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[The history of wound dressings (author's transl)]. | The introduction of antisepsis and asepsis brought about decisive changes in the dressing of wounds. For thousands of years, dressing material had been regarded as protection for wounds, absorbent material, or a base for healing substances, while healing per secundam intentionem by the production of "pus laudabile" was... | ['Anti-Infective Agents, Local', 'Antisepsis', 'Bandages', 'Female', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Male', 'Wound Healing', 'Wound Infection'] | 1,107,717 | [['D27.505.954.122.187'], ['N06.850.780.200.450.150'], ['E07.101'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.762.891'], ['C01.947']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Risk factors for coronary heart disease in a black population. | A matched case control study using population-based controls was done over a 2-year period in an urban, public hospital setting. The object of the study was to determine if the established risk factors for coronary heart disease--hypertension, diabetes mellitus, hypercholesterolemia, cigarette smoking, low socioeconomi... | ['African Americans', 'Case-Control Studies', 'Coronary Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Risk Factors'] | 1,495,111 | [['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Outcomes of Surgical Management of Borderline Hip Dysplasia: A Systematic Review. | Background: Multiple reports have detailed clinical outcomes in surgically treated patients with borderline hip dysplasia. The purpose of this systematic review was to define patient outcomes following these surgical interventions.Methods: Searches were developed using an iterative process of gathering and evaluating t... | ['Arthroplasty, Replacement, Hip', 'Arthroscopy', 'Disability Evaluation', 'Hip Dislocation', 'Humans', 'Osteotomy', 'Patient Reported Outcome Measures', 'Reoperation'] | 32,577,106 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E01.370.400'], ['C05.550.518.384', 'C26.289.384', 'C26.531.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.555.580'], ['E05.318.308.980.344.500', 'N03.349.380.210.750', 'N04.761... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Histoautoradiographic detection of oxytocin- and vasopressin-binding sites in the telencephalon of the rat. | Localization of oxytocin- and vasopressin-binding sites has so far been studied in the rat brain by means of film autoradiographs. The disposal of iodinated ligands with high specificity has allowed us to develop histoautoradiography on emulsion-coated sections and to reinvestigate on a microscopic scale the distributi... | ['Animals', 'Autoradiography', 'Binding Sites', 'Oxytocin', 'Rats', 'Receptors, Oxytocin', 'Receptors, Vasopressin', 'Telencephalon', 'Vasopressins'] | 8,394,391 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G02.111.570.120'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.695.630', 'D12.776.543.750.720.600.630', 'D12.776.543.750.750.555.630', 'D12.776.543.750.750.660.600'], ['D... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recovery of Previously Uncultured Bacterial Genera from Three Mediterranean Sponges. | Sponges often harbour a dense and diverse microbial community. Presently, a large discrepancy exists between the cultivable bacterial fraction from sponges and the community in its natural environment. Here, we aimed to acquire additional insights into cultivability of (previously uncultured) bacteria from three sponge... | ['Animals', 'Anti-Bacterial Agents', 'Bacteria', 'Bacteriological Techniques', 'Biodiversity', 'Flavobacteriaceae', 'Microbiota', 'Phylogeny', 'Porifera', 'RNA, Ribosomal, 16S'] | 28,695,385 | [['B01.050'], ['D27.505.954.122.085'], ['B03'], ['E01.370.225.875.150', 'E05.200.875.150'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B03.440.080.190', 'B03.440.400.425.310'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.050.500.802'], ['D13... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Heterologous expression of active manganese peroxidase from Phanerochaete chrysosporium using the baculovirus expression system. | The cDNA encoding Mn peroxidase isozyme H4 from Phanerochaete chrysosporium was recombined into a baculovirus and heterologously expressed in Sf9 cells. The recombinant Mn peroxidase has the same molecular weight as the native enzyme as determined by SDS-PAGE and cross-reacts with a Mn peroxidase-specific antibody. The... | ['Baculoviridae', 'Chrysosporium', 'DNA, Fungal', 'Electrophoresis, Polyacrylamide Gel', 'Gene Expression', 'Isoelectric Point', 'Isoenzymes', 'Molecular Weight', 'Peroxidases', 'Protein Processing, Post-Translational', 'Recombinant Proteins', 'Substrate Specificity'] | 1,898,410 | [['B04.280.065', 'B04.525.100'], ['B01.300.381.170'], ['D13.444.308.300'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.297'], ['E05.301.300.663.500', 'G02.300.500'], ['D08.811.348', 'D12.776.800.300'], ['G02.494'], ['D08.811.682.732'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.670... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of Opioids Given to Facilitate Mechanical Ventilation on Sleep Apnea After Extubation in the Intensive Care Unit. | Study Objectives: Following extubation in the intensive care unit (ICU), upper airway (UA) edema and respiratory depressants may promote UA dysfunction. We tested the hypothesis that opioids increase the risk of sleep apnea early after extubation.Methods: Fifty-six ICU patients underwent polysomnography the night after... | ['Adult', 'Aged', 'Airway Extubation', 'Airway Obstruction', 'Analgesics, Opioid', 'Body Mass Index', 'Exhalation', 'Female', 'Humans', 'Intensive Care Units', 'Lung', 'Male', 'Middle Aged', 'Perioperative Period', 'Polysomnography', 'Prospective Studies', 'Respiration, Artificial', 'Sleep', 'Sleep Apnea, Obstructive',... | 29,182,729 | [['M01.060.116'], ['M01.060.116.100'], ['E02.041.249', 'E05.008'], ['C08.618.846.185'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G09.772.70... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enzymatic digestion of liposome-bound polysaccharides: evidence of bridging mechanism. | Laminarin, a water-soluble polysaccharide is known to induce aggregation and fusion of liposomes. Using laminarin specific lysing enzymes for multi-lamellar liposomes their aggregation was found to be fully reversible, in contrast to small unilamellar liposomes for which irreversible fusion is the main process. Moreove... | ['Dose-Response Relationship, Drug', 'Erythrocytes', 'Glucans', 'Humans', 'Liposomes', 'Models, Chemical', 'Phosphatidylcholines', 'Polysaccharides', 'Protein Binding', 'Thermodynamics', 'Time Factors'] | 11,316,062 | [['G07.690.773.875', 'G07.690.936.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D05.750.078.562', 'D09.698.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E05.599.495'], ['D10.570.755.375.760.400.800'], ['D09.698']... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A 130 year record of pollution in the Suances estuary (southern Bay of Biscay): implications for environmental management. | Geochemical composition (Al, Zn, Pb, Cd, Cu, Ni, Cr and As) and foraminiferal assemblages in surface and core sediments were determined to assess the current situation and the recent environmental transformation of the Suances estuary (southern Bay of Biscay, Spain). Dating of the historical record has been achieved us... | ['Animals', 'Environmental Monitoring', 'Geologic Sediments', 'Invertebrates', 'Oceans and Seas', 'Rivers', 'Spain', 'Time Factors', 'Water Pollutants', 'Water Pollution'] | 18,760,425 | [['B01.050'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['B01.050.500'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['Z01.542.846'], ['G01.910.857'], ['D27.888.284.903'], ['N06.850.460.790']] | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Prognosis in medically-treated coronary artery disease: influence of ejection fraction compared to other parameters. | The prognostic value of the left ventricular ejection fraction(EF) was compared to that of other commonly used indices--severity of coronary artery disease, left ventricular end-diastolic pressure, cardiac index, and abnormal ECG--in 144 patients with coronary artery disease followed for an average of 14 months on medi... | ['Adult', 'Aged', 'Boston', 'Cardiac Output', 'Coronary Disease', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Prognosis'] | 1,157,237 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['E01.370.370.380.150', 'G09.330.380.124'], ['C14.280.647.250', 'C14.907.585.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The oxidant-antioxidant system and cognitive functions in patients undergoing elective abdominal operations under various general anesthesia modes]. | The impact of various general anesthesia modes on the oxidant-antioxidant system (OAS) and cognitive function in the perioperative period was studied in 88 patients (4 groups, each comprising 22 patients according to the mode of general anesthesia who had undergone elective surgery for chronic calculous cholecystitis (... | ['Abdomen', 'Anesthesia, General', 'Anesthetics, Intravenous', 'Antioxidants', 'Cognition', 'Elective Surgical Procedures', 'Humans', 'Lipid Peroxidation', 'Neuropsychological Tests', 'Oxidative Stress', 'Propofol', 'Reactive Oxygen Species'] | 19,827,202 | [['A01.923.047'], ['E03.155.197'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['F02.463.188'], ['E04.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.515', 'G03.295.531.587'], ['F04.711.513'], ['G03.673', 'G07.775.7... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of MRI in patient selection for CRT. | Magnetic resonance imaging has great potential for aiding in the selection of patients who will respond to CRT. MRI is the only imaging tool that can simultaneously assess mechanical dyssynchrony, determine the amount and location of myocardial scar tissue, and map the location of cardiac venous anatomy-three important... | ['Cardiac Pacing, Artificial', 'Humans', 'Magnetic Resonance Imaging', 'Patient Selection'] | 18,986,405 | [['E02.331.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.581.500.653', 'N04.590.731']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Synthesis of RNA polymerase subunits in Escherichia coli mutants]. | The influence of mutations in structural genes of beta- and beta'-subunits of RNA polymerase upon the synthesis of these subunits in E. coli cells have been investigated. An amber-mutation ts22 in the beta-subunit gene decreases the intracellular concentration of this subunit and the rate of its synthesis. At the same ... | ['DNA-Directed RNA Polymerases', 'Escherichia coli', 'Genes', 'Mutation', 'Species Specificity'] | 802,775 | [['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.365.590'], ['G16.824']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of both colorimetric and fluorescence heparinase activity assays using fondaparinux as substrate. | Because tumors and other diseases are characterized by increased heparanase levels, human heparanase is a promising drug target and diagnostic marker. Therefore, methods are needed to determine heparanase activity and to examine potential inhibitors. Because of substrate comparability, we used the bacterial enzyme hepa... | ['Biosensing Techniques', 'Colorimetry', 'Flavobacterium', 'Fondaparinux', 'Glucuronidase', 'Heparin', 'Heparin Lyase', 'Heparitin Sulfate', 'Humans', 'Polysaccharides', 'Spectrometry, Fluorescence', 'Substrate Specificity'] | 22,579,846 | [['E05.601.043'], ['E05.196.922.250'], ['B03.440.080.190.250', 'B03.440.400.425.310.250'], ['D09.698.629.429'], ['D08.811.277.450.426'], ['D09.698.373.400'], ['D08.811.520.241.700.512'], ['D09.698.373.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels. | Transcription factor GATA-1 is essential for the development of the erythroid lineage. To ascertain whether strict control of GATA-1 expression level is necessary for achieving proper erythropoiesis, we established transgenic mouse lines expressing green fluorescent protein (GFP) under the control of the GATA-1 gene he... | ['Animals', 'Bone Marrow Cells', 'Calcium', 'DNA-Binding Proteins', 'Erythroid Precursor Cells', 'Erythroid-Specific DNA-Binding Factors', 'Erythropoiesis', 'GATA1 Transcription Factor', 'Gene Expression Regulation', 'Green Fluorescent Proteins', 'Immunophenotyping', 'Liver', 'Luminescent Proteins', 'Mice', 'Mice, Tran... | 12,893,747 | [['B01.050'], ['A11.148', 'A15.378.316'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.260'], ['A11.148.378.590.837.250', 'A11.443.240.497', 'A11.872.378.590.817.250', 'A15.378.316.378.590.837.250'], ['D12.776.260.235', 'D12.776.930.216'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.776.260.235.50... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thromboxane A2 and prostacyclin release in bleeding time blood during primary haemostasis in healthy individuals. | It is generally believed that prostacyclin (PGI2) generation is greatly stimulated when blood vessels are injured, even by minor trauma, such as venepuncture. The Simplate technique for measuring skin bleeding time was adapted to quantify by radioimmunoassay PGI2 and thromboxane A2 (TXA2) in the emerging blood, as the ... | ['6-Ketoprostaglandin F1 alpha', 'Adult', 'Bleeding Time', 'Epoprostenol', 'Female', 'Hemostasis', 'Humans', 'Male', 'Middle Aged', 'Platelet Count', 'Skin', 'Thromboxane A2', 'Thromboxane B2'] | 3,279,726 | [['D10.251.355.255.550.400.350', 'D10.251.355.325.450', 'D23.469.050.175.725.400.350'], ['M01.060.116'], ['E01.370.225.625.625.100', 'E05.200.625.625.100', 'G09.188.087'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neural reactivity to visual food stimuli is reduced in some areas of the brain during evening hours compared to morning hours: an fMRI study in women. | The extent that neural responsiveness to visual food stimuli is influenced by time of day is not well examined. Using a crossover design, 15 healthy women were scanned using fMRI while presented with low- and high-energy pictures of food, once in the morning (6:30-8:30 am) and once in the evening (5:00-7:00 pm). Diets ... | ['Attention', 'Body Composition', 'Brain', 'Brain Mapping', 'Eating', 'Female', 'Food', 'Habits', 'Humans', 'Hunger', 'Magnetic Resonance Imaging', 'Neuropsychological Tests', 'Periodicity', 'Photic Stimulation', 'Photoperiod', 'Reward', 'Visual Perception', 'Young Adult'] | 25,753,781 | [['F02.830.104.214'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.300', 'J02.500'], ['F01.145.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.293.391', 'G07.203.650.... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Recombinant alpha 2a interferon and polycythemia vera: clinical results and biological evaluation by means of Fourier-transform infrared microspectroscopy. | Polycythemia vera (PV) is a chronic myeloproliferative disease. The use of recombinant alpha 2a Interferon (IFN) therapy in this disease is a novel approach. We applied Fourier-transform infrared microspectroscopy (FT-IR-M) to investigate the behavior and therapeutic responsiveness of PV patients treated with IFN. A sp... | ['Blood Cell Count', 'Hematocrit', 'Hemoglobins', 'Humans', 'Interferon alpha-2', 'Interferon-alpha', 'L-Lactate Dehydrogenase', 'Megakaryocytes', 'Polycythemia Vera', 'Recombinant Proteins', 'Spectroscopy, Fourier Transform Infrared'] | 7,957,805 | [['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.44... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of acute cocaine administration on the DOI-induced head-twitch response in reserpinized mice. | Previously it was shown that acute cocaine administration dose dependently reduces the 5-HT2-receptor-mediated DOI [(+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane]-induced head-twitch response (HTR) in mice via indirect stimulation of the inhibitory adrenergic alpha 2- and serotonergic 5-HT1A receptors. In additio... | ['Amphetamines', 'Animals', 'Behavior, Animal', 'Cocaine', 'Dose-Response Relationship, Drug', 'Male', 'Mice', 'Mice, Inbred ICR', 'Norepinephrine', 'Reserpine', 'Serotonin', 'Serotonin Receptor Agonists'] | 7,816,879 | [['D02.092.471.683.152'], ['B01.050'], ['F01.145.113'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['D02... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Repeat prostate-specific antigen (PSA) test before prostate biopsy: a 20% decrease in PSA values is associated with a reduced risk of cancer and particularly of high-grade cancer. | OBJECTIVES: To analyse the impact of repeating a prostate-specific antigen (PSA) level assessment on prostate biopsy decision in a cohort of men undergoing prostate biopsy.PATIENTS AND METHODS: From 2015 onwards, we consecutively enrolled, at a single institution in Italy, men undergoing 12-core transrectal ultrasonogr... | ['Aged', 'Biopsy, Large-Core Needle', 'Humans', 'Image-Guided Biopsy', 'Male', 'Middle Aged', 'Prostate', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Risk Factors', 'Ultrasonography, Interventional'] | 29,533,522 | [['M01.060.116.100'], ['E01.370.225.500.384.100.119.750', 'E01.370.225.998.054.119.750', 'E01.370.388.100.100.750', 'E04.074.119.750', 'E04.665.100.750', 'E05.200.500.384.100.119.750', 'E05.200.998.054.119.750', 'E05.242.384.100.119.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.384.100.370',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Human tissue factor pathway inhibitor fused to CD4 binds both FXa and TF/FVIIa at the cell surface. | Tissue factor pathway inhibitor (TFPI) is one of the main regulators of the tissue factor (TF) pathway of coagulation. To tether human TFPI to the cell surface, full length or truncated TFPI lacking the third Kunitz domain were fused with domains three and four and the carboxy-terminal sequence of human CD4. Constructs... | ['Animals', 'CD4 Antigens', 'Cell Line', 'Cell Membrane', 'Factor VIIa', 'Factor Xa', 'Gene Expression', 'Humans', 'Lipoproteins', 'Mice', 'Peptide Fragments', 'Protein Binding', 'Protein Structure, Tertiary', 'Recombinant Fusion Proteins', 'Sensitivity and Specificity', 'Thromboplastin'] | 9,423,800 | [['B01.050'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['A11.251.210'], ['A11.284.149'], ['D08.811.277.656.300.760.300', 'D08.811.277.656.959.350.300', 'D12.776.124.125.325.300', 'D23.119.325.300'], ['D08.811.277.656.300.760.315', 'D08.811... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modeling and simulation of biopharmaceutical performance. | Biopharmaceutical performance refers to the influence of pharmaceutical formulation variables on in vivo performance. New drug product success depends on formulation design for sufficient bioavailability for clinically desired dosing. Regulatory interest in biopharmaceutical performance includes batch-to-batch consiste... | ['Administration, Oral', 'Biological Availability', 'Computer Simulation', 'Drug Approval', 'Drug Design', 'Drugs, Generic', 'Humans', 'Models, Biological', 'Pharmaceutical Preparations', 'Therapeutic Equivalency', 'United States', 'United States Food and Drug Administration'] | 24,747,237 | [['E02.319.267.100'], ['G03.787.151', 'G07.690.725.129'], ['L01.224.160'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D26.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['D26'], ['G03.787.559', 'G07.690.725.89... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Development and experimental validation of a three-dimensional finite element model of the human scapula. | A new modelling approach, using a combination of shell and solid elements, has been adopted to develop a realistic three-dimensional finite element (FE) model of the human scapula. Shell elements were used to represent a part of the compact bone layer (i.e. the outer cortical layer) and the very thin and rather flat pa... | ['Aged', 'Aged, 80 and over', 'Cadaver', 'Compressive Strength', 'Computer Simulation', 'Elasticity', 'Female', 'Finite Element Analysis', 'Humans', 'Imaging, Three-Dimensional', 'In Vitro Techniques', 'Models, Biological', 'Radiography', 'Reproducibility of Results', 'Scapula', 'Sensitivity and Specificity', 'Stress, ... | 15,116,900 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.260.224'], ['G01.374.180'], ['L01.224.160'], ['G01.374.590'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.481'], ['E05.599.395'], ['E01.370.350.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effect of air pollution on hospital admissions for systemic lupus erythematosus in Bengbu, China: a time series study. | Recently, exposure to air pollutants has been associated with the development and progression of systemic lupus erythematosus (SLE). The current study aims to evaluate the effects of air pollutants on SLE hospital admissions in Bengbu, China. We performed distributed lag non-linear model combined with quasi-Poisson gen... | ['Adult', 'Air Pollutants', 'Air Pollution', 'China', 'Environmental Exposure', 'Female', 'Hospitalization', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Particulate Matter', 'Risk Factors', 'Time Factors'] | 31,615,325 | [['M01.060.116'], ['D27.888.284.101'], ['N06.850.460.100'], ['Z01.252.474.164'], ['N06.850.460.350'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['D20.633'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sebaceous carcinoma in the clinical setting of non-Hodgkin lymphoma: the Mayo Clinic experience. | OBJECTIVES: Non-Hodgkin lymphoma is a hematologic malignancy associated with the more aggressive behavior of some forms of skin cancer. An association between sebaceous carcinoma and immunosuppression has been identified, but the behavior of sebaceous carcinoma in the setting of non-Hodgkin lymphoma has not been studie... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Basal Cell', 'Carcinoma, Squamous Cell', 'Colonic Neoplasms', 'Fatal Outcome', 'Head and Neck Neoplasms', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Muir-Torre Syndrome', 'Neoplasms, Second Primary', 'Prostatic Neoplasms', 'Retrospective Studies', 'Sebaceous Gland Neoplasms', ... | 23,675,639 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E05.318.308.985.550.325', 'N01.224... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A phase I and pharmacokinetic study of lapatinib in combination with infusional 5-fluorouracil, leucovorin and irinotecan. | BACKGROUND: This study determined the optimally tolerated regimen (OTR) of oral lapatinib administered in combination with infusional 5-fluorouracil (5-FU), leucovorin and irinotecan (FOLFIRI) and assessed the safety, tolerability and pharmacokinetics of the combination.PATIENTS AND METHODS: Twenty-five patients were e... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Camptothecin', 'Female', 'Fluorouracil', 'Humans', 'Irinotecan', 'Lapatinib', 'Leucovorin', 'Male', 'Middle Aged', 'Neoplasms', 'Quinazolines', 'Tandem Mass Spectrometry'] | 17,846,021 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.132.151'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.151.425'], ['D03.633.100.786.516'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['M01.060.116.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Induction of hypoxia in normal and malignant tissues by changing the oxygen affinity of hemoglobin--implications for therapy. | The drug BW12C, which increases the oxygen affinity of hemoglobin, reduces oxygen availability to tissues. This results in protection against radiation damage to the hemopoietic system and epidermal Langerhans cells in CBA mice. The drug also protects against beta-irradiation damage in pig epidermis. BW12C increases th... | ['Aldehydes', 'Animals', 'Antineoplastic Agents', 'Benzaldehydes', 'Combined Modality Therapy', 'Hemoglobins', 'Mice', 'Neoplasms, Experimental', 'Oxygen', 'Radiation-Protective Agents', 'Swine'] | 3,759,551 | [['D02.047'], ['B01.050'], ['D27.505.954.248'], ['D02.047.222'], ['E02.186'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.619', 'E05.598.500.496'], ['D01.268.185.550', 'D01.362.670'], ['D27.505.696.706.776', 'D27.720.799.763'], ['B01.050.150.900.649.313.500.880']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High Fructose and High Fat Exert Different Effects on Changes in Trabecular Bone Micro-structure. | OBJECTIVES: To compare the effects of high-fat diet (HFD) and high-fructose diet (HFrD) on bone metabolism at different time points, dynamically observe the bone histology and femur trabecular micro-architecture, and analyze the underlying mechanisms.METHODS: Sixty -Five male 6- to 7-week-old C57BL/6J mice were given H... | ['Animals', 'Body Weight', 'Bone Density', 'Cancellous Bone', 'Cathepsin K', 'Core Binding Factor Alpha 1 Subunit', 'Diet, High-Fat', 'Femur', 'Fructose', 'Lipid Metabolism', 'Lipids', 'Male', 'Matrix Metalloproteinase 9', 'Mice', 'Mice, Inbred C57BL', 'RNA, Messenger', 'X-Ray Microtomography'] | 29,484,349 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G11.427.100'], ['A10.165.265.414'], ['D08.811.277.656.224.405', 'D08.811.277.656.262.500.156', 'D08.811.277.656.300.200.156'], ['D12.776.930.155.200.100'], ['G07.203.650.240.267'], ['A02.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The urinary catheter as a bronchial blocker. | Two cases are described in which problems with double lumen bronchial tubes occurred during thoracic surgery. A urinary catheter inserted down one lumen of each of the tubes enabled one lung anaesthesia to be continued without disturbing the surgery. This technique should be considered before abandoning one lung anaest... | ['Anesthesia, Inhalation', 'Bronchi', 'Esophageal Neoplasms', 'Female', 'Humans', 'Intubation', 'Middle Aged', 'Pneumonectomy', 'Urinary Catheterization'] | 6,859,477 | [['E03.155.197.197'], ['A04.411.125'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585', 'E05.497'], ['M01.060.116.630'], ['E04.620', 'E04.928.600.600'], ['E01.370.390.820', 'E02.148.947', 'E05.157.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple pregnancies and the risk of diabetes mellitus in postmenopausal women. | OBJECTIVE: We aimed to investigate whether the number of pregnancies during childbearing age was associated with diabetes in postmenopausal women with no history of gestational diabetes.METHODS: Our data source was the continuous National Health and Nutrition Examination Survey 1999 to 2014. We selected 9,138 postmenop... | ['Adult', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Logistic Models', 'Middle Aged', 'Nutrition Surveys', 'Postmenopause', 'Pregnancy', 'Pregnancy, Multiple', 'Risk Factors', 'United States'] | 31,453,963 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mapping pathogenic mutations suggests an innovative structural model for the pendrin (SLC26A4) transmembrane domain. | Human pendrin (SLC26A4) is an anion transporter mostly expressed in the inner ear, thyroid and kidney. SLC26A4 gene mutations are associated with a broad phenotypic spectrum, including Pendred Syndrome and non-syndromic hearing loss with enlarged vestibular aqueduct (ns-EVA). No experimental structure of pendrin is cur... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Genetic Predisposition to Disease', 'Goiter, Nodular', 'Hearing Loss, Sensorineural', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Membrane Proteins', 'Membrane Transport Proteins', 'Models, Molecular', 'Mutation', 'Protein Domains', 'Protein Structure, Secondary'... | 27,771,369 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C23.550.291.687.500', 'G05.380.355'], ['C19.874.283.501'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anterior cruciate ligament reconstruction and determination of tunnel size and graft obliquity. | OBJECTIVE: Increase in ACL (anterior cruciate ligament) reconstructions has led to a higher prevalence of patients with postoperative symptoms which require investigation. We aimed to investigate the utility of magnetic resonance imaging (MRI) and computer tomography (CT) in determining tunnel size and graft obliquity ... | ['Adult', 'Aged', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Reconstruction', 'Female', 'Femur', 'Graft Survival', 'Humans', 'Imaging, Three-Dimensional', 'Knee Joint', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Retrospective Studies', 'Tibia', 'Tomography, X-Ray Computed', 'Transplantation, A... | 25,720,703 | [['M01.060.116'], ['M01.060.116.100'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E04.555.110.026', 'E04.680.101.026'], ['A02.835.232.043.150'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['A02.835.583.475'], ['E01.370.350.825.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Male violence, stress, and neuroendocrine parameters in pregnancy: a pilot study. | Stress during pregnancy has been associated with a number of adverse outcomes. This study compared and correlated neuroendocrine parameters in women (n=8) who self-reported battering during their pregnancy to those in women who did not (n=8). Women who identified themselves as having a violent relationship with an inti... | ['Adrenocorticotropic Hormone', 'Biomarkers', 'Case-Control Studies', 'Female', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Linear Models', 'Male', 'Midwestern United States', 'Pilot Projects', 'Pituitary-Adrenal System', 'Placenta', 'Pregnancy', 'Pregnancy Complications', 'Rural Population', 'Severi... | 16,552,950 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Differential beta-band event-related desynchronization during categorical action sequence planning. | A primate study reported the existence of neurons from the dorso-lateral prefrontal cortex which fired prior to executing categorical action sequences. The authors suggested these activities may represent abstract level information. Here, we aimed to find the neurophysiological representation of planning categorical ac... | ['Adult', 'Beta Rhythm', 'Brain', 'Cognition', 'Cortical Synchronization', 'Evoked Potentials', 'Female', 'Humans', 'Linear Models', 'Magnetoencephalography', 'Male', 'Motor Activity', 'Photic Stimulation', 'Psychomotor Performance'] | 23,527,215 | [['M01.060.116'], ['E01.370.376.300.150.750', 'E01.370.405.245.287.750', 'G07.265.087.750', 'G11.561.127.750'], ['A08.186.211'], ['F02.463.188'], ['E01.370.376.300.437.500', 'E01.370.405.245.575.500', 'G07.265.256.249'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Human keratinocyte locomotion: the effect of selected cytokines. | Epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) are two powerful mitogens for human keratinocytes that also have been shown to promote the healing of in vivo wounds. Transforming growth factor-beta (TGF-beta) markedly inhibits human keratinocyte proliferation and growth and yet has been shown to... | ['Animals', 'Cattle', 'Cell Movement', 'Cells, Cultured', 'Collagen', 'Epidermal Growth Factor', 'Fibroblast Growth Factor 2', 'Humans', 'Keratinocytes', 'Pituitary Gland', 'Tissue Extracts', 'Transforming Growth Factor beta'] | 1,728,636 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychiatric medications: adverse cutaneous drug reactions. | Psychiatric medications are among the most widely prescribed medications in the United States. Adverse cutaneous drug reactions are associated with psychiatric medications in approximately 2% to 5% of the individuals for whom they are prescribed. Although most adverse cutaneous drug reactions associated with psychotrop... | ['Antipsychotic Agents', 'Drug Eruptions', 'Drug Hypersensitivity', 'Humans', "Practice Patterns, Physicians'", 'Psychotropic Drugs', 'Skin Diseases', 'Time Factors'] | 23,245,981 | [['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['C17.800.174.600', 'C20.543.206.380', 'C25.100.468.380'], ['C20.543.206', 'C25.100.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.374.577', 'N05.300.625'], ['D27.505.954.427.700'], ['C17.800'], ['G01.910.857'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of a computerized alert on the management of hypokalemia in hospitalized patients. | BACKGROUND: Electrolyte abnormalities, including hypokalemia, are frequently encountered among hospitalized patients. Their management, when carefully audited, reveals major shortcomings.OBJECTIVE: To evaluate the effect of a computerized alert on the management of severe hypokalemia in hospitalized patients.METHODS: A... | ['Female', 'Humans', 'Hypokalemia', 'Israel', 'Laboratories, Hospital', 'Male', 'Medical Records Systems, Computerized', 'Middle Aged'] | 12,546,610 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.565'], ['Z01.252.245.500.375'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['M01.06... | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Enantioselective quenching of room-temperature phosphorescence lifetimes of proteins: bovine and human serum albumins. | Enantioselective quenching of the room-temperature phosphorescence (RTP) lifetime of proteins was demonstrated due to the effects of various external chiral quenching agents. In the absence of quenchers, the RTP lifetimes for bovine serum albumin (BSA) and human serum albumin (HSA) were found to be 5.0 +/- 0.2 and 4.0 ... | ['Animals', 'Cattle', 'Chemistry, Physical', 'Dose-Response Relationship, Drug', 'Humans', 'Luminescent Proteins', 'Molecular Conformation', 'Phosphorus', 'Protein Conformation', 'Protein Denaturation', 'Serum Albumin', 'Serum Albumin, Bovine', 'Spectrometry, Fluorescence', 'Stereoisomerism', 'Temperature'] | 17,274,655 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['H01.181.529'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.532'], ['G02.111.570.820'], ['D01.268.666'], ['G02.111.570.820.709'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['D12.776.034.841', 'D12.776.12... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Coupled, multi-strain epidemic models of mutating pathogens. | We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties of a general class of multi-strain epidemic models in which the infectious compar... | ['Bacteria', 'Basic Reproduction Number', 'Communicable Diseases', 'Drug Resistance, Microbial', 'Epidemics', 'Humans', 'Models, Theoretical'] | 29,288,702 | [['B03'], ['E05.318.308.985.525.080', 'N01.224.935.597.080', 'N06.850.335.125', 'N06.850.505.400.975.525.080', 'N06.850.520.308.985.525.080'], ['C01.221', 'C23.550.291.531'], ['G06.225', 'G07.690.773.984.269'], ['N06.850.290.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rare anatomic entity of quadricuspid aortic valve with aortic insufficiency: a case report. | Quadricuspid aortic valve (QAV) is a rare congenital heart defect that often causes symptomatic aortic insufficiency in adulthood, imposing valve replacement. Herein, we describe one unusual case of QAV which underwent valve replacement uneventfully. | ['Aged', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Humans', 'Male'] | 17,666,310 | [['M01.060.116.100'], ['A07.541.510.110'], ['C14.280.484.048.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Combination of a subcutaneous ICD in a patient with a baroreceptor activation device: Feasibility, safety, and precautions: A Case Report. | We present a case of a patient with a baroreflex activation therapy (BAT) receiving a subcutaneous implantable cardioverter defibrillator (S-ICD). We anticipated two possible hazardous interactions between the two devices. Stimulation by the BAT could be adjudicated as noise and result in underdetection of ventricular ... | ['Adult', 'Death, Sudden, Cardiac', 'Defibrillators, Implantable', 'Equipment Design', 'Feasibility Studies', 'Humans', 'Implantable Neurostimulators', 'Male', 'Pressoreceptors'] | 28,543,085 | [['M01.060.116'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E05.320'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.319.381', 'E07.695.202.381'], ['A... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The morphology of DNA solution in an open fluidic channel studied by non-contact AFM. | The morphologies of pure buffer solution and DNA-containing solution in an open fluidic channel with rectangle cross section (1 microm in width and 150 nm in depth) have been explored using non-contact AFM. A remarkable feature is that a uniform nano-scale trench (approximately 15 nm deep and 14 microm long) on the sur... | ['DNA', 'Microfluidics', 'Microscopy, Atomic Force', 'Solutions'] | 17,353,127 | [['D13.444.308'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['D26.776']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Enhancement of erythrocytic adenosine deaminase following treatment of AIDS-related complex/AIDS patients with zidovudine. | The levels of adenosine deaminase (ADA) were determined in the erythrocytes of 10 patients with sexually transmitted HIV-1 infection [five cases with AIDS-related complex (ARC) and five with AIDS] before and after therapy with zidovudine (azidothymidine; AZT). A linear increase in ADA activity was observed during the s... | ['AIDS-Related Complex', 'Acquired Immunodeficiency Syndrome', 'Adenosine Deaminase', 'Adult', 'Anemia', 'Erythrocytes', 'HIV-1', 'Humans', 'Zidovudine'] | 2,261,134 | [['C01.221.250.875.080', 'C01.221.812.640.400.080', 'C01.778.640.400.080', 'C01.925.782.815.616.400.080', 'C01.925.813.400.080', 'C01.925.839.080', 'C20.673.480.080'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Correlations between gross and microscopic lesions in carcinogenic studies in mice. | Microscopic diagnoses of a number of spontaneous and induced neoplasms in mice were correlated with the gross findings of the ED01 and a number of other carcinogenic studies conducted at NCTR to determine the value of detailed histopathologic examinations in bioassay testing. The results indicated that for organs such ... | ['Adrenal Cortex Neoplasms', 'Animals', 'Carcinogens', 'Harderian Gland', 'Liver Neoplasms, Experimental', 'Lung Neoplasms', 'Lymphoma', 'Lymphoma, Large B-Cell, Diffuse', 'Mammary Neoplasms, Experimental', 'Mice', 'Neoplasms, Experimental', 'Pituitary Neoplasms', 'Urinary Bladder Neoplasms'] | 6,988,540 | [['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['B01.050'], ['D27.888.569.100'], ['A13.445'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.557.386', 'C15.604.515.569',... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The motor neuron response to SMN1 deficiency in spinal muscular atrophy. | INTRODUCTION: The purpose of this study was to measure and analyze motor unit number estimation (MUNE) values longitudinally in spinal muscular atrophy (SMA).METHODS: Sixty-two children with SMA types 2 and 3 were observed prospectively for up to 42 months. Longitudinal electrophysiological data were collected, includi... | ['Action Potentials', 'Adaptation, Physiological', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cohort Studies', 'Disease Progression', 'Electromyography', 'Exons', 'Female', 'Gene Deletion', 'Homozygote', 'Humans', 'Infant', 'Linear Models', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Motor Neurons', 'Musc... | 23,893,312 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G07.025', 'G16.012.500'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.656'], ['E01.370.405.255', 'E01.370.530.255'], ['G05.360.340.024.340.13... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Intra-operative fractures in cementless bipolar hemiarthroplasty. | PURPOSE: To compare patients with or without intra-operative fracture during cementless bipolar hemiarthroplasty.METHODS: Records of 76 men and 202 women who underwent cementless bipolar hemiarthroplasty for femoral neck fractures were reviewed. Patients with and without intra-operative fractures and patients with diff... | ['Aged', 'Aged, 80 and over', 'Female', 'Femoral Neck Fractures', 'Femur', 'Fracture Fixation, Internal', 'Hemiarthroplasty', 'Hip Fractures', 'Humans', 'Intraoperative Complications', 'Male', 'Middle Aged', 'Reoperation', 'Treatment Outcome'] | 26,321,555 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['A02.835.232.043.150'], ['E04.555.300.300'], ['E04.555.110.110.482', 'E04.650.110.482', 'E04.680.101.110.482'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation and partial characterization of bovine periodontal ligament alkaline phosphatase. | An alkaline phosphatase which binds to hyaluronate with a high affinity has been extracted from the bovine periodontal ligament and purified. The procedure consisted of extraction with a 10 mM Tris/Mg buffer containing 0.1% Nonidet P40, chromatography on a hyaluronate-conjugated Affi-Gel 15, and fast protein liquid chr... | ['Alkaline Phosphatase', 'Animals', 'Cattle', 'Chromatography, Affinity', 'Chromatography, Gel', 'Chromatography, High Pressure Liquid', 'Electrophoresis, Polyacrylamide Gel', 'Extracellular Matrix Proteins', 'Hyaluronic Acid', 'Membrane Glycoproteins', 'Periodontal Ligament'] | 2,133,795 | [['D08.811.277.352.650.035'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.170'], ['E05.196.181.400.250'], ['E05.196.181.400.300'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.860.300'], ['D09.698.373.475'], ['D12.776.395.550', 'D12.776.543.550'], ['A14.549.167.646.771']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Amperometric determination of lipid hydroperoxides. | A new amperometric analytical technique for measuring lipid hydroperoxides is described. The technique is based on the measurement of cathodic current due to the reduction of ferricinium ion formed as result of the oxidation of ferrocene by lipid hydroperoxides. The effects of pH and applied potential were investigated... | ['Ascorbic Acid', 'Chemical Phenomena', 'Chemistry, Physical', 'Electric Conductivity', 'Electrochemistry', 'Electrodes', 'Ferrous Compounds', 'Hydrogen-Ion Concentration', 'Linoleic Acids', 'Linolenic Acids', 'Lipid Peroxides', 'Metallocenes', 'Organometallic Compounds', 'Oxidation-Reduction', 'Oxygen', 'Sensitivity a... | 7,762,791 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['G02'], ['H01.181.529'], ['G01.358.500.249.277'], ['H01.181.529.307'], ['E07.305.250'], ['D01.490.200'], ['G02.300'], ['D10.251.355.310.515', 'D10.251.355.343.500'], ['D10.251.355.310.640'], ['D01.248.497.158.685.750.637', 'D01.339.431.374.637', 'D01.650.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of an integrated transitional care program for stroke survivors living in a rural community: a randomized controlled trial. | OBJECTIVE: To evaluate the effect of an integrated transitional care program on health outcomes in stroke survivors based on an original community for healthcare.DESIGN: A pilot randomized controlled trial with blinded assessment. Randomization by statistician using computer-generated, random numbers concealed in opaqu... | ['Aged', 'China', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Discharge', 'Pilot Projects', 'Rural Population', 'Secondary Prevention', 'Stroke', 'Stroke Rehabilitation', 'Transitional Care'] | 32,026,701 | [['M01.060.116.100'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.125', 'N02.421.585.400.610', 'N04.590.233.727.210.125'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['N01.600.72... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[Determination of Total Sulfur Dioxide in Chinese Herbal Medicines via Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry]. | As an important treatment method, sulfur fumigation plays an essential role in the production and preservation of traditional Chinese herbal medicines. Although there is strict regulation on the use of sulfur dioxide, the abuse of sulfur dioxide still occurred from time to time. And the public faces a high risk of expo... | ['Drugs, Chinese Herbal', 'Microwaves', 'Spectrum Analysis', 'Sulfur Dioxide', 'Tandem Mass Spectrometry'] | 27,209,762 | [['D20.215.784.500.350', 'D26.335'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['E05.196.867'], ['D01.362.810', 'D01.650.550.850.925', 'D01.875.825.925'], ['E05.196.566.880']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Site of hydrolysis of collagen by hot trichloroacetic acid. | When calfskin collagen is treated with trichloroacetic acid at 90 degrees C, it is hydrolyzed to a mixture of peptides, some of which are quite small. Cleavage of collagen by acid seems to occur at bonds between proline (or hydroxyproline) and other amino acids, with only a limited specificity for which amino acid dona... | ['Amino Acids', 'Animals', 'Cattle', 'Collagen', 'Hot Temperature', 'Hydrolysis', 'Hydroxyproline', 'Peptides', 'Proline', 'Trichloroacetic Acid'] | 134,865 | [['D12.125'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.380'], ['D12.125.072.401.623.478'], ['D12.644'], ['D12.125.072.40... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of exercise training on skeletal muscle cytokine expression in the elderly. | Aging is associated with increased circulating pro-inflammatory and lower anti-inflammatory cytokines. Exercise training, in addition to improving muscle function, reduces these circulating pro-inflammatory cytokines. Yet, few studies have evaluated changes in the expression of cytokines within skeletal muscle after ex... | ['Adolescent', 'Adult', 'Aged', 'Cytokines', 'Exercise', 'Humans', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Young Adult'] | 24,434,040 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['M01.060.116.815']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
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