Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Reading sentences of words with rotated letters: An eye movement study. | Participants' eye movements were measured as they read sentences in which individual letters within words were rotated. Both the consistency of direction and the magnitude of rotation were manipulated (letters rotated all in the same direction, or alternately clockwise and anti-clockwise, by 30° or 60°). Each sentence ... | ['Adult', 'Attention', 'Eye Movement Measurements', 'Eye Movements', 'Female', 'Fixation, Ocular', 'Humans', 'Linguistics', 'Male', 'Pattern Recognition, Visual', 'Reading'] | 30,328,773 | [['M01.060.116'], ['F02.830.104.214'], ['E01.370.380.230', 'E01.370.405.245.787'], ['G11.427.410.140', 'G14.350'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['L01.559.423.557']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins. | We previously proposed a role for the two-pore domain potassium (K2P) channel TREK-1 in hyperoxia (HO)-induced lung injury. To determine whether redundancy among the three TREK isoforms (TREK-1, TREK-2, and TRAAK) could protect from HO-induced injury, we now examined the effect of deletion of all three TREK isoforms in... | ['Animals', 'Gene Expression Regulation', 'Hyperoxia', 'Lipopolysaccharides', 'Lung Injury', 'Mice', 'Mice, Knockout', 'Potassium Channels', 'Potassium Channels, Tandem Pore Domain', 'Pulmonary Surfactant-Associated Proteins', 'Transcription Factors'] | 28,839,101 | [['B01.050'], ['G05.308'], ['C23.888.852.567'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['C08.381.520', 'C26.891.554'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.31... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exposure of a diurnal mosquito vector to floral mimics: Foraging responses, feeding patterns, and significance for sugar bait technology. | Food location by mosquitoes is mediated by resource-derived olfactory and visual signals. Smell sensation is intermittent and dependent on the environment, whereas visual signals are continual and precede olfactory cues. Success of mosquito bait technology, where olfactory cues are used for attraction, is being impeded... | ['Aedes', 'Animals', 'Feeding Behavior', 'Female', 'Flowers', 'Male', 'Mosquito Vectors', 'Plant Nectar', 'Smell', 'Sugars'] | 29,856,985 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A18.024.249.500'], ['N06.850.335.188.100.500.500', 'N06.850.520.203.375.100.500.500'], ['D20.215.780'], ['F02.830.816.643', 'G11.561.790.643'], ['D09.947']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effects of urbanization on Lepomis macrochirus using the comet assay. | Urbanization has been linked to increased concentrations of polycyclic aromatic hydrocarbons in natural waterways. This study was designed to examine the impact of urbanization and a wastewater treatment plant by investigating the impact on field-collected bluegill (Lepomis macrochirus). Results show a significant incr... | ['Animals', 'Comet Assay', 'DNA Damage', 'Ecosystem', 'Environmental Monitoring', 'Geologic Sediments', 'Perciformes', 'Polycyclic Aromatic Hydrocarbons', 'Urbanization', 'Water Pollutants, Chemical'] | 22,885,057 | [['B01.050'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['B01.050.150.900.493.602'], ['D02.455.426.559.847', 'D04.615'], ['I01.880.853.400.726'], ['D27... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Mapping and assessment of personal and professional development skills in a pharmacy curriculum. | BACKGROUND: Health sciences programs are increasingly expanding their curricula to bridge foundational scientific knowledge with needed skills to practice and patient care. The primary objectives of this study are to 1) assess whether the personal and professional development (PPD) subdomains (self-assessment, leadersh... | ['Curriculum', 'Education, Pharmacy', 'Female', 'Humans', 'Job Satisfaction', 'Male', 'Personal Satisfaction', 'Professional Competence', 'Program Evaluation', 'Students, Pharmacy', 'United States'] | 26,772,809 | [['I02.158'], ['I02.358.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['F01.145.677'], ['I02.399.630'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['M01.848.769.768'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The artificial bowel sphincter for faecal incontinence: a single centre study. | BACKGROUND AND AIMS: Faecal incontinence (FI) is a socially devastating problem. The treatment algorithm depends on the aetiology of the problem. Large anal sphincter defects can be treated by sphincter replacement procedures: the dynamic graciloplasty and the artificial bowel sphincter (ABS).MATERIALS AND METHODS: Pat... | ['Adult', 'Aged', 'Anal Canal', 'Artificial Organs', 'Device Removal', 'Fecal Incontinence', 'Female', 'Humans', 'Male', 'Manometry', 'Middle Aged', 'Pressure', 'Prospective Studies', 'Prosthesis Implantation', 'Prosthesis-Related Infections', 'Reoperation', 'Severity of Illness Index', 'Time Factors', 'Treatment Outco... | 17,929,038 | [['M01.060.116'], ['M01.060.116.100'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['E07.858.082'], ['E04.199'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['M01.060.116.630'], ['G01.374.715'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.50... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures. | Bioartificial liver (BAL) devices have been developed to treat patients undergoing acute liver failure. One of the most important parameters to consider in designing these devices is the oxygen consumption rate of the seeded hepatocytes which are known to have oxygen consumption rates 10 times higher than most other ce... | ['3T3 Cells', 'Animals', 'Cells, Cultured', 'Coculture Techniques', 'Computer Simulation', 'Female', 'Liver', 'Liver Function Tests', 'Liver, Artificial', 'Mice', 'Models, Biological', 'Oxygen Consumption', 'Rats', 'Rats, Inbred Lew', 'Tissue Engineering'] | 17,054,120 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['A11.251'], ['E05.481.500.374'], ['L01.224.160'], ['A03.620'], ['E01.370.372.460'], ['E07.858.082.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['G03.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.280', 'B01.050... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Effects of a 50 Hz magnetic field on Dictyostelium discoideum (Protista). | Some studies have demonstrated that a few biological systems are affected by weak, extremely low frequency (ELF) electromagnetic fields (EMFs), lower than 10 mT. However, to date there is scanty evidence of this effect on Protists in the literature. Due to their peculiarity as single-cell eukaryotic organisms, Protists... | ['Animals', 'Cell Aggregation', 'Cell Differentiation', 'Cell Division', 'Cholinesterases', 'Dictyostelium', 'Electromagnetic Fields'] | 16,715,524 | [['B01.050'], ['G04.198.251'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D08.811.277.352.100.170'], ['B01.046.550.200.300'], ['G01.358.500.260', 'G01.358.750.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Lactobacillus paracasei Culture Filtrates and Artichoke Polyphenols on Cytokine Production by Dendritic Cells. | The most recent trend in research on probiotic bacteria aims at the exploitation of bioactive bacterial compounds that are responsible for health-promoting effects and suitable for medical applications. Therefore, the main purpose of this study was to ascertain if the immunomodulatory effects of L. paracasei strains on... | ['Cynara scolymus', 'Cytokines', 'Dendritic Cells', 'Humans', 'Lactobacillus paracasei', 'Plant Extracts', 'Polyphenols', 'Probiotics'] | 27,754,398 | [['B01.650.940.800.575.912.250.100.269.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.559', 'B03.510.460.400.410.475.475.559', 'B03.510.550.450.475.559'], ['D20.215... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The effectiveness of alcohol policies in 4-year public universities. | The objective of this study was to evaluate the type of alcohol policy in place in 4-year public universities against the odds of heavy drinking. Data was collected during the months of April-June 2010 using the Core Alcohol and Drug Survey. The participants included a random sample of undergraduate students from 4 pub... | ['Adolescent', 'Alcohol Drinking', 'Female', 'Health Policy', 'Humans', 'Male', 'Midwestern United States', 'Public Sector', 'Students', 'Universities', 'Young Adult'] | 21,928,102 | [['M01.060.057'], ['F01.145.317.269'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.510'], ['I01.795', 'N04.452.633.890'], ['M01.848'], ['I02.783.830', 'J03.832.830'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Management of anesthesia for the multiply-injured patient with associated craniocerebral injuries]. | Adequate anaesthesiological care of polytraumatized patients with associated craniocerebral trauma has the primary objective of preventing secondary cerebral damage. To this end, it is absolutely necessary to be aware of the physiology and pathophysiology of intracranial pressure, cerebral perfusion pressure and cerebr... | ['Anesthesia', 'Barbiturates', 'Brain Injuries', 'Cerebrovascular Circulation', 'Homeostasis', 'Humans', 'Intracranial Pressure', 'Intubation, Intratracheal', 'Nitrous Oxide', 'Perfusion', 'Skull Fractures'] | 6,869,762 | [['E03.155'], ['D03.383.742.698.253'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G09.330.100.159'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.561.170.505'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['D01.362.635.625', 'D01.625.550.550', 'D01.650.550.587.650'], ['E05.68... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Post-transfusion-transmitted hepatitis C virus infection: a study on thalassemia and hemodialysis patients in southeastern Iran. | Thalassemia and hemodialysis patients are at risk of blood-transmitted infections due to their long-term need for blood transfusion. Nowadays, control of viral infections, including HCV infections, is one of the main tasks of blood transfusion services worldwide. Therefore, the aim of this research was to investigate t... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Renal Dialysis', 'Thalassemia', 'Transfusion Reaction', 'Young Adult'] | 21,340,738 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Minocycline ameliorates D-galactose-induced memory deficits and loss of Arc/Arg3.1 expression. | Dysfunction of learning and memory is widely found in many neurological diseases. Understanding how to preserve the normal function of learning and memory will be extremely beneficial for the treatment of these diseases. However, the possible protective effect of minocycline in memory impairment is unknown. We used the... | ['Animals', 'Brain-Derived Neurotrophic Factor', 'Cytoskeletal Proteins', 'Disease Models, Animal', 'Galactose', 'Gene Expression Regulation', 'Humans', 'Male', 'Maze Learning', 'Memory Disorders', 'Minocycline', 'Nerve Tissue Proteins', 'Proto-Oncogene Proteins c-fos', 'Rats'] | 27,497,819 | [['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['D12.776.220'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D09.947.875.359.377'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.874.500'], ['C10.597.606.525', 'C23.888.592.604.529... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA mismatch detection using a pyrene-excimer-forming probe. | A pyrene-excimer-forming probe allowed the easy and sensitive detection of a single base mismatch in target DNA. This was due to the faster strand exchange rate compared to a fully-matched target. | ['Base Pair Mismatch', 'DNA', 'DNA Mutational Analysis', 'Pyrenes', 'Spectrometry, Fluorescence', 'Thermodynamics'] | 15,886,787 | [['G05.365.590.060'], ['D13.444.308'], ['E05.393.760.700.300'], ['D02.455.426.559.847.799', 'D04.615.799'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['G01.906']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The first prenylation step in hyperforin biosynthesis. | Prenylation reactions contribute considerably to the diversity of natural products. Polyprenylated secondary metabolites include hyperforin which is both quantitatively and pharmacologically a major constituent of the medicinal plant Hypericum perforatum (St. John's wort). Cell cultures of the related species Hypericum... | ['Bridged Bicyclo Compounds', 'Dimethylallyltranstransferase', 'Hydrogen-Ion Concentration', 'Hypericum', 'Iron', 'Molecular Structure', 'Phloroglucinol', 'Protein Prenylation', 'Solubility', 'Substrate Specificity', 'Temperature', 'Terpenes'] | 15,649,510 | [['D02.455.426.100.080', 'D04.075.080'], ['D08.811.913.225.400'], ['G02.300'], ['B01.650.940.800.575.912.250.859.625.500'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.389.657.684'], ['G02.111.660.871.790.600.400', 'G02.111.672.500', 'G02.111.691.600.400', 'G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cancer incidence in an area of radioactive fallout downwind from the Nevada Test Site. | Exposures in southwestern Utah to radioactive fallout (1951 through 1962) from atmospheric nuclear detonations at the Nevada Test Site (NTS) were followed by smaller exposures (1962 through 1979) from venting of underground nuclear detonations. The cancer incidence in a 1951 cohort (4, 125) of Mormon families in southw... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Animals', 'Child', 'Child, Preschool', 'Epidemiologic Methods', 'Female', 'Humans', 'Infant', 'Leukemia, Radiation-Induced', 'Life Style', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Nevada', 'Radiation Dosage', 'Radioactive Fallout', 'Radioactive Pollutants',... | 6,690,781 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.337.650', 'C04.682.512', 'C26.733.345', 'G01.750.748.500.345'], ['F01... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A comparative study of the MATRICS and IntegNeuro cognitive assessment batteries. | Cognitive impairment is prevalent in schizophrenia and is related to poorer functional and treatment outcomes. Cognitive assessment is therefore now a routine component of clinical trials of new treatments for schizophrenia. The current gold-standard for cognitive assessment in clinical trials for schizophrenia is the ... | ['Adolescent', 'Adult', 'Attention', 'Central Nervous System Depressants', 'Cognition', 'Cognition Disorders', 'Diagnostic and Statistical Manual of Mental Disorders', 'Ethanol', 'Female', 'Humans', 'Language', 'Learning', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Neuropsychological Tests', 'Problem Solving', 'Psyc... | 20,455,131 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104.214'], ['D27.505.696.277', 'D27.505.954.427.210'], ['F02.463.188'], ['F03.615.250'], ['L01.453.245.945.200'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540.407'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Subcutaneous administration of carrier erythrocytes: slow release of entrapped agent. | Carrier erythrocytes administered subcutaneously in mice release encapsulated molecules at the injection site and through cells that escape the injection site. One day postinjection, the efflux of encapsulated [14C]sucrose, [3H]inulin, and 51Cr-hemoglobin from the injection site was 45, 55, and 65%, respectively. Intac... | ['Administration, Cutaneous', 'Animals', 'Chromium Radioisotopes', 'Drug Carriers', 'Erythrocyte Transfusion', 'Hemoglobins', 'Inulin', 'Kinetics', 'Mice', 'Mice, Inbred ICR', 'Sucrose', 'Tissue Distribution', 'Tritium'] | 3,219,194 | [['E02.319.267.120.060'], ['B01.050'], ['D01.268.556.175.500.349', 'D01.268.956.124.500.349', 'D01.496.212.349', 'D01.496.749.213', 'D01.552.544.175.500.349'], ['D26.255.260', 'E02.319.300.380'], ['E02.095.135.140.275'], ['D12.776.124.400', 'D12.776.422.316.762'], ['D05.750.078.562.855.750', 'D09.301.915.750', 'D09.698... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laparoscopic repair of an internal supravesical hernia: a rare hernia causing small bowel obstruction. | The application of diagnostic laparoscopy in emergency surgery has facilitated a wide range of endoscopic operative procedures. We report an extremely rare case of a patient who had a bowel obstruction caused by an internal supravesical hernia that was repaired via a minimally invasive technique. Abdominal computed tom... | ['Diagnosis, Differential', 'Hernia, Ventral', 'Humans', 'Intestinal Neoplasms', 'Intestinal Obstruction', 'Laparoscopy', 'Male', 'Middle Aged', 'Urinary Bladder', 'Urinary Bladder Neoplasms'] | 12,574,931 | [['E01.171'], ['C23.300.707.374.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411', 'C06.301.371.411', 'C06.405.249.411', 'C06.405.469.491'], ['C06.405.469.531'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['A05.810.890'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of a neck-bridging device for endovascular coiling of a wide-necked middle cerebral artery aneurysm. | Endovascular treatment of wide-necked bifurcation intracranial aneurysms is technically challenging, often requiring adjunctive devices such as stents or balloons to maintain coil mass within the aneurysm sac. Comaneci is a radiopaque embolization-assist device that can be temporarily deployed in the parent artery acro... | ['Endovascular Procedures', 'Female', 'Humans', 'Intracranial Aneurysm', 'Middle Aged', 'Self Expandable Metallic Stents', 'Treatment Outcome'] | 32,051,321 | [['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['M01.060.116.630'], ['E07.695.750.750'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae. | The gene encoding the galactose permease of Saccharomyces cerevisiae (GAL2) was cloned. The clone restores galactose permease activity to gal2 yeasts and is regulated by galactose in a manner similar to other GAL gene products (GAL1, -7, and -10). Experiments with temperature-conditional secretory mutants indicated tha... | ['Biological Transport', 'Cell Membrane', 'Genes', 'Genes, Fungal', 'Genetic Engineering', 'Membrane Transport Proteins', 'Monosaccharide Transport Proteins', 'Mutation', 'Plasmids', 'Promoter Regions, Genetic', 'Saccharomyces cerevisiae', 'beta-Galactosidase'] | 3,082,856 | [['G03.143'], ['A11.284.149'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['E05.393.420'], ['D12.776.157.530', 'D12.776.543.585'], ['D12.776.157.530.500', 'D12.776.543.585.500'], ['G05.365.590'], ['G05.360.600'], ['G02.111.570.080.689.675', 'G05.360.0... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of succinylation on the membrane activity and conformation of a short cecropin A-melittin hybrid peptide. | A 15-residue hybrid peptide (KWKLFKKIGAVLKVL-amide) incorporating partial sequences of cecropin A and melittin causes the release of carboxyfluoresceine encapsulated in phosphatidylcholine liposomes. Succinylation of the amino groups in the N-terminus and lysine side chains inhibits the effect of this peptide on liposo... | ['Amino Acid Sequence', 'Anti-Bacterial Agents', 'Antimicrobial Cationic Peptides', 'Cell Membrane Permeability', 'Liposomes', 'Melitten', 'Membranes', 'Molecular Sequence Data', 'Phosphatidylcholines', 'Protein Structure, Secondary', 'Structure-Activity Relationship', 'Succinates'] | 7,948,737 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.954.122.085'], ['D12.644.050', 'D12.776.543.695.054'], ['G03.143.335', 'G04.175'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D12.644.050.550', 'D12.776.543.695.054.550', 'D20.888.065.115.580', 'D23.946.833.065.115.580'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Structural analysis of Cu(II) ligation to the 5'-GMP nucleotide by pulse EPR spectroscopy. | Simple copper salts are known to denature poly d(GC). On the other hand, copper complexes of substituted 1,4,7,10,13-pentaazacyclohexadecane-14,16-dione are able to convert the right-handed B form of the same DNA sequence to the corresponding left-handed Z form. A research program was started in order to understand why... | ['Copper', 'DNA', 'DNA, Z-Form', 'Electron Spin Resonance Spectroscopy', 'Guanosine Monophosphate', 'Ligands', 'Molecular Structure', 'Nucleic Acid Conformation', 'Organometallic Compounds'] | 17,415,596 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D13.444.308'], ['D13.444.308.574', 'G02.111.570.820.486.493', 'G05.360.580.493'], ['E05.196.867.519.274'], ['D03.633.100.759.646.454.400', 'D13.695.667.454.400', 'D13.695.827.426.400'], ['D27.720.470.480'], ['G02.111.570', 'G02.466'], ['G02.111.570.820.486',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[NO-ergic function of the Lugaro and Golgi cells in the rabbit cerebellar cortex]. | The distribution of NADPH-diaphorase was studied cytochemically in the rabbit cerebellar cortex. In the granular layer the Golgi cells with positive reaction were found. The highest activity of enzyme was observed in the cytoplasm of intermediate cells of Lugaro, synaptic neurons of Landau, large and middle sized Golgi... | ['Animals', 'Cerebral Cortex', 'Cytoplasm', 'Diffusion', 'Endoplasmic Reticulum, Rough', 'NADPH Dehydrogenase', 'Neurons', 'Nitric Oxide', 'Purkinje Cells', 'Rabbits'] | 9,312,906 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['A11.284.430.214'], ['G01.202', 'G02.196'], ['A11.284.430.214.190.875.248.300', 'A11.284.430.214.190.875.811.740.300'], ['D08.811.682.608.550'], ['A08.675', 'A11.671'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['A08.186.211.132.810.428... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Challenges to the improvement of obstetric care in maternity hospitals of a large Brazilian city: an exploratory qualitative approach on contextual issues. | BACKGROUND: Maternal morbidity and mortality are still serious public health concerns in Brazil, and access to quality obstetric care is one critical point of this problem. Despite efforts, obstetric care quality problems and sub-optimal/poor outcomes persist. The study aimed to identify contextual elements that would ... | ['Anesthesiologists', 'Brazil', 'Communication', 'Cooperative Behavior', 'Delivery of Health Care', 'Female', 'Hospitals, Maternity', 'Hospitals, Public', 'Humans', 'Leadership', 'Maternal Health Services', 'Neonatologists', 'Nurses', 'Obstetric Nursing', 'Obstetrics', 'Patient Care Team', 'Physicians', 'Pregnancy', 'P... | 30,477,475 | [['M01.526.485.140.040', 'M01.526.485.810.040', 'N02.360.140.040', 'N02.360.810.040'], ['Z01.107.757.176'], ['F01.145.209', 'L01.143'], ['F01.145.813.115'], ['N04.590.374', 'N05.300'], ['N02.278.421.556.366'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['N02.421.143.620', 'N0... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 |
Trauma on eight wheels. A study of roller skating injuries in Seattle. | Thirty-five fractures secondary to roller skating accidents from March 15 to October 1, 1979 were treated in the University of Washington-affiliated hospitals. Twenty-eight involved the wrist and elbow. Only three were in skeletally immature individuals. Sixty-three percent of the patients were female with the 20- to 3... | ['Adolescent', 'Adult', 'Ankle Injuries', 'Athletic Injuries', 'Child', 'Debridement', 'Female', 'Fracture Fixation', 'Fractures, Closed', 'Fractures, Open', 'Humans', 'Male', 'Middle Aged', 'Radius Fractures', 'Skating', 'Sports', 'Washington', 'Wrist Injuries'] | 6,829,840 | [['M01.060.057'], ['M01.060.116'], ['C26.558.100'], ['C26.115'], ['M01.060.406'], ['E04.176'], ['E04.555.300'], ['C26.404.124'], ['C26.404.311'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C26.088.268.556', 'C26.404.562'], ['I03.450.642.845.700'], ['I03.450.642.845'], ['Z01.107.567.875.560.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Crossmodal representation of a functional robotic hand arises after extensive training in healthy participants. | The way in which humans represent their own bodies is critical in guiding their interactions with the environment. To achieve successful body-space interactions, the body representation is strictly connected with that of the space immediately surrounding it through efficient visuo-tactile crossmodal integration. Such a... | ['Adult', 'Artificial Limbs', 'Body Image', 'Female', 'Hand', 'Humans', 'Learning', 'Male', 'Motor Skills', 'Physical Stimulation', 'Practice, Psychological', 'Robotics', 'Space Perception', 'Time Factors', 'Touch Perception', 'Visual Perception'] | 24,296,252 | [['M01.060.116'], ['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['F01.752.747.792.110', 'F02.463.593.112'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['F02.808.260'], ['E05.723'], ['F02.463.425.674'], ['H01.671.293.643', 'J01.897.104.834', 'L01.22... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[Coagulation tests in septic surgical patients]. | AIM: To determine whether sequential change in coagulation parameters such as activated partial thromboplastin time (aPTT), prothrombin time (PT), platelets count and fibrinogen level may predict the outcome of patients in sepsis.STUDY DESIGN: Cohort longitudinal study.PATIENTS AND METHODS: Patients with positive two o... | ['Adult', 'Aged', 'Blood Coagulation Tests', 'Disseminated Intravascular Coagulation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Sepsis', 'Surgical Procedures, Operative', 'Survival Rate'] | 15,756,805 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.625.115', 'E05.200.625.115'], ['C15.378.100.220', 'C15.378.463.250', 'C15.378.925.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['C01.757', 'C23.550.470.790.500'], ['E04'], ['E05.318.308.985.550.900', 'N01.224.935.698.826',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Amiodarone-related thyroid dysfunction. | Nowadays, amiodarone is the most commonly used antidysrhythmic drug in clinical practice. It is highly effective in the management of recurrent ventricular dysrhythmias, paroxysmal supraventricular dysrhythmias, including atrial fibrillation and flutter, and in the maintenance of sinus rhythm after electrical cardiover... | ['Amiodarone', 'Anti-Arrhythmia Agents', 'Atrial Fibrillation', 'Heart Failure', 'Humans', 'Hypothyroidism', 'Thyroid Gland', 'Thyrotoxicosis'] | 25,348,560 | [['D03.633.100.127.075'], ['D27.505.954.411.097'], ['C14.280.067.198', 'C23.550.073.198'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['A06.300.900'], ['C19.874.397.685']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Digestion of bovine milk proteins in patients with a high jejunostomy. | Digestion of milk proteins was studied in short-bowel patients. After ingestion of water, purified beta-lactoglobulin (beta-Ig), or skim milk, effluents were collected at the stoma. The flow rate of the effluent peaked in the first 30-min period after ingestion and returned to the basal value within the first 60 min. A... | ['Blotting, Western', 'Caseins', 'Digestion', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Intestinal Mucosa', 'Ions', 'Jejunostomy', 'Male', 'Milk Proteins', 'Nitrogen', 'Osmolar Concentration', 'Short Bowel Syndrome'] | 1,877,510 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['G07.203.650.250', 'G10.261.190'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['D01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Carbohydrate-binding plasma proteins from the gastropod Biomphalaria glabrata: strain specificity and the effects of trematode infection. | As lectins are believed to mediate non-self-recognition in molluscs, carbohydrate-binding proteins (CBP) from the circulating plasma of the gastropod Biomphalaria glabrata were harvested by affinity chromatography using six different monosaccharides as ligands. Pools of plasma were derived from B. glabrata of either th... | ['Animals', 'Biomphalaria', 'Carrier Proteins', 'Chromatography, Affinity', 'Echinostoma', 'Electrophoresis, Polyacrylamide Gel', 'Hemolymph', 'Receptors, Cell Surface', 'Schistosoma mansoni', 'Species Specificity'] | 1,330,758 | [['B01.050'], ['B01.050.500.644.400.750.185'], ['D12.776.157'], ['E05.196.181.400.170'], ['B01.050.500.500.736.715.360.310'], ['E05.196.401.402', 'E05.301.300.319'], ['A13.453'], ['D12.776.543.750'], ['B01.050.500.500.736.715.770.680.700'], ['G16.824']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Response of Three Different Viruses to Interferon Priming and Dithiothreitol Treatment of Avian Cells. | UNLABELLED: We have previously shown that the replication of avian reovirus (ARV) in chicken cells is much more resistant to interferon (IFN) than the replication of vesicular stomatitis virus (VSV) or vaccinia virus (VV). In this study, we have investigated the role that the double-stranded RNA (dsRNA)-activated prote... | ['Animals', 'Antiviral Agents', 'Cell Line', 'Chickens', 'Dithiothreitol', 'Eukaryotic Initiation Factor-2', 'Host-Pathogen Interactions', 'Interferons', 'Orthoreovirus, Avian', 'Phosphorylation', 'Protein Processing, Post-Translational', 'Vaccinia virus', 'Vesiculovirus', 'Virus Replication', 'eIF-2 Kinase'] | 27,440,902 | [['B01.050'], ['D27.505.954.122.388'], ['A11.251.210'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['D12.776.835.725.868.249'], ['G06.462', 'G16.527.200'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['B04.820.223.719.590... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An unusual combination of parathyroid adenoma, medullary and papillary thyroid carcinoma. | The coexistence of medullary thyroid carcinoma (MTC), papillary thyroid carcinoma (PTC) and parathyroid adenoma is an uncommon clinical entity. Here, we report a case of MTC, PTC, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. The patient had ne... | ['Carcinoma, Neuroendocrine', 'Carcinoma, Papillary', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Multiple Endocrine Neoplasia', 'Parathyroid Neoplasms', 'Parathyroidectomy', 'Thyroid Neoplasms', 'Thyroidectomy'] | 23,737,320 | [['C04.557.465.625.650.240', 'C04.557.470.200.025.370', 'C04.557.580.625.650.240'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.322.400', 'C04.651.600', 'C04.700.630', 'C16.320.700.630', 'C19.344.400'], ['C04.588.322.525', ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Implicit attitude towards pictures of back-stressing activities in pain-free subjects and patients with low back pain: an affective priming study. | In this paper, it is investigated whether an implicit evaluative-negative attitude towards back-stressing activities exists in pain-free subjects and in chronic low back pain patients. Using an affective priming task, it was investigated whether pictures of threatening back-stressing movements (primes) facilitate (resp... | ['Adult', 'Attitude', 'Case-Control Studies', 'Female', 'Humans', 'Low Back Pain', 'Male', 'Motor Activity', 'Photic Stimulation'] | 12,527,315 | [['M01.060.116'], ['F01.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['F01.145.632', 'G11.427.410.698'], ['E05.723.729']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The paraplegic - intermittent catheterization and other advances. | Intermittent catheterization has been well described and found to be very successful in the management of what is possibly the major cause of severe illness, even death, in paraplegia - namely bladder infection. It is an extremely simple technique to introduce and contrary to widespread opinion, does not entail a great... | ['Female', 'Humans', 'Male', 'Paraplegia', 'Self Care', 'Urinary Catheterization', 'Urination Disorders'] | 7,064,004 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.622.669', 'C23.888.592.636.637'], ['E02.900', 'I03.050.563', 'N02.421.784.680'], ['E01.370.390.820', 'E02.148.947', 'E05.157.500'], ['C12.777.934', 'C13.351.968.934']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Effect of thymoxamine on the human pupil. | The specificity of thymoxamine, an alpha-adrenoceptor antagonist was determined from in vitro organ bath studies using isolated preparations of canine saphenous and portal mesenteric veins. It was found that thymoxamine interacts mainly with postjunctional alpha-adrenoceptors. The miotic effects of topical thymoxamine ... | ['Adult', 'Animals', 'Dogs', 'Dose-Response Relationship, Drug', 'Female', 'Half-Life', 'Humans', 'In Vitro Techniques', 'Male', 'Mesenteric Veins', 'Moxisylyte', 'Norepinephrine', 'Phenylephrine', 'Propranolol', 'Pupil', 'Saphenous Vein', 'Time Factors', 'Xylazine'] | 6,221,938 | [['M01.060.116'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A07.015.908.670.385'], ['D02.092.668.387.500'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Phalangeal microgeodic syndrome. | Phalangeal microgeodic syndrome specifically affects the phalanges in infants. The radiographic findings are characterized by small lacunae measuring less than 1 mm in diameter in the phalanges. The symptoms usually subside spontaneously within 2 to 3 months with no residual deformity. Accurate diagnosis is possible by... | ['Adolescent', 'Bone Diseases', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Female', 'Fingers', 'Humans', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Radiography', 'Syndrome'] | 11,500,148 | [['M01.060.057'], ['C05.116'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.350.825.500'], ['E01.370.350.700'], ['C23.550.288.500']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A baseline-free procedure for transformation models under interval censorship. | An important property of Cox regression model is that the estimation of regression parameters using the partial likelihood procedure does not depend on its baseline survival function. We call such a procedure baseline-free. Using marginal likelihood, we show that an baseline-free procedure can be derived for a class of... | ['Algorithms', 'Breast Neoplasms', 'China', 'Computer Simulation', 'Humans', 'Likelihood Functions', 'Markov Chains', 'Proportional Hazards Models', 'Survival Analysis'] | 16,328,572 | [['G17.035', 'L01.224.050'], ['C04.588.180', 'C17.800.090.500'], ['Z01.252.474.164'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
High protein-induced glomerular hypertrophy is vascular endothelial growth factor-dependent. | BACKGROUND: Various growth factors and cytokines have been implicated in different forms of kidney enlargement such as renal growth following induction of diabetes, unilateral nephrectomy, and exposure to high protein diet. Vascular endothelial growth factor (VEGF) is essential for normal renal development and plays a ... | ['Animals', 'Antibodies', 'Body Weight', 'Dietary Proteins', 'Eating', 'Endothelial Growth Factors', 'Female', 'Heart', 'Hypertrophy', 'Insulin-Like Growth Factor I', 'Kidney Diseases', 'Kidney Glomerulus', 'Liver', 'Lymphokines', 'Mice', 'Mice, Inbred Strains', 'Organ Size', 'Vascular Endothelial Growth Factor A', 'Va... | 11,967,009 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.283', 'G10.261.330'], ['D12.644.276.390',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
ISO 9000:2000 revisions and their implications. | The planned revision of the ISO 9000 series of standards means that all medical device companies will have to revise their quality systems to align them with the new ISO 9000:2000 standards. This overview outlines the changes and the factors companies need to consider, and highlights future standards activity. | ['Equipment and Supplies', 'Industry', 'Quality Control'] | 11,010,320 | [['E07'], ['J01.576'], ['J01.897.608']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Distribution of ASIC4 transcripts in the adult wild-type mouse brain. | Acid-sensing ion channel 4 (ASIC4) belongs to the ASIC gene family of neuronal proton-gated cation channels, and is the least understood subtype among the members. Previous studies of ASIC4 expression in the mammalian central nervous system have shown that ASIC4 is abundantly expressed in the spinal cord and in various... | ['Acid Sensing Ion Channels', 'Animals', 'Brain', 'Choline O-Acetyltransferase', 'In Situ Hybridization', 'Male', 'Mice, Inbred C57BL', 'Neurons', 'RNA, Messenger'] | 28,461,138 | [['D12.776.157.530.400.875.050', 'D12.776.543.550.450.875.050', 'D12.776.543.585.400.875.050', 'D12.776.631.024'], ['B01.050'], ['A08.186.211'], ['D08.811.913.050.134.180'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Strain wave elastography in response assessment to neo-adjuvant chemotherapy in patients with locally advanced breast cancer. | OBJECTIVE: The study was conducted to study the role of strain wave elastography in evaluating the response to neo-adjuvant chemotherapy (NACT) in patients with locally advanced breast cancer (LABC).METHODS: In this Institutional review board approved study, 86 patients of LABC were investigated with strain wave elasto... | ['Breast', 'Breast Neoplasms', 'Chemotherapy, Adjuvant', 'Elasticity Imaging Techniques', 'Female', 'Humans', 'Middle Aged', 'Neoadjuvant Therapy', 'Sensitivity and Specificity', 'Treatment Outcome'] | 31,045,431 | [['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E02.186.170', 'E02.319.170'], ['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.186.450'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.85... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conversion Furlow palatoplasty: salvage of speech after straight-line palatoplasty and "incomplete intravelar veloplasty". | INTRODUCTION: The straight-line palatoplasty with intravelar veloplasty (IVVP) is one option for cleft palate repair. However, not all IVVPs are performed uniformly. Many IVVPs only address the medialmost portion of the levator muscle, an "incomplete IVVP," failing to completely dissect and adequately transpose the ent... | ['Adolescent', 'Child', 'Child, Preschool', 'Humans', 'Palate, Soft', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Speech Disorders', 'Velopharyngeal Insufficiency'] | 16,641,625 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.617.780'], ['E04.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], [... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of the testosterone metabolite dihydrotestosterone and 5 alpha-androstan-3 alpha,17 beta-diol on very long chain fatty acid metabolism in X-adrenoleukodystrophic fibroblasts. | X-Adrenoleukodystrophy (X-ALD) is a peroxisomal disorder associated with the abnormal accumulation of very long chain fatty acids (VLCFA) in plasma and tissues. We have demonstrated that the androgen dihydrotestosterone (DHT) and 5 alpha-androstan-3 alpha,17 beta-diol (3 alpha-diol) have favorable effect on VLCFA metab... | ['Adrenoleukodystrophy', 'Androstane-3,17-diol', 'Cells, Cultured', 'Child', 'Cholesterol Esters', 'Dihydrotestosterone', 'Fatty Acids', 'Fibroblasts', 'Humans', 'Lipid Metabolism', 'Oxidation-Reduction', 'Peroxisomes', 'Skin'] | 12,865,096 | [['C10.228.140.163.100.084', 'C10.228.140.163.100.362.250', 'C10.228.140.695.625.250', 'C10.314.400.250', 'C10.597.606.360.455.124', 'C16.320.322.500.124', 'C16.320.400.525.124', 'C16.320.565.189.084', 'C16.320.565.189.362.250', 'C16.320.565.663.100', 'C18.452.132.100.084', 'C18.452.132.100.362.250', 'C18.452.648.189.0... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The CT findings of acute thyroiditis and acute suppurative thyroiditis. | Although acute thyroiditis often has a distinctive clinical presentation, this relatively uncommon entity can occasionally be confused with other inflammatory processes. In general, the earlier the diagnosis of acute thyroiditis is established, the lower is the frequency and severity of its attendant complications. Com... | ['Acute Disease', 'Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Thyroiditis', 'Thyroiditis, Suppurative', 'Tomography, X-Ray Computed'] | 3,147,442 | [['C23.550.291.125'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C19.874.871'], ['C01.830.840', 'C19.874.871.910'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Drosophila homologues of adenomatous polyposis coli (APC) and the formin diaphanous collaborate by a conserved mechanism to stimulate actin filament assembly. | BACKGROUND: Vertebrate APC collaborates with Dia through its Basic domain to assemble actin filaments.RESULTS: Despite limited sequence homology between the vertebrate and Drosophila APC Basic domains, Drosophila APC1 collaborates with Dia to stimulate actin assembly in vitro.CONCLUSION: The mechanism of actin assembly... | ['Actins', 'Animals', 'CapZ Actin Capping Protein', 'Carrier Proteins', 'Cytoskeletal Proteins', 'Drosophila Proteins', 'Drosophila melanogaster', 'Formins', 'Kinetics', 'Peptide Fragments', 'Profilins', 'Protein Multimerization', 'Protein Structure, Tertiary', 'Sequence Homology, Amino Acid', 'Tumor Suppressor Protein... | 23,558,679 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D05.750.078.730.032.500', 'D12.776.210.500.227', 'D12.776.220.525.032.500'], ['D12.776.157'], ['D12.776.220'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D05.750.078.730.333', 'D12.776.220.525.333... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Selective" D-1 and D-2 receptor antagonists fail to differentially alter supersensitive locomotor behavior in the rat. | The dopamine receptor antagonists SCH 23390 and spiperone show highly selective in vitro affinity for D-1 and D-2 dopamine receptor subtypes, respectively. We studied the effects of these selective antagonists on the supersensitive locomotor response to apomorphine in rats following 6- hydroxydopamine (6OHDA) lesions o... | ['Animals', 'Apomorphine', 'Benzazepines', 'Hydroxydopamines', 'Kinetics', 'Male', 'Motor Activity', 'Nucleus Accumbens', 'Oxidopamine', 'Rats', 'Rats, Inbred Strains', 'Receptors, Dopamine', 'Receptors, Dopamine D1', 'Receptors, Dopamine D2', 'Spiperone'] | 2,946,915 | [['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['D03.633.100.079'], ['D02.092.311.342.478', 'D02.455.426.559.389.657.166.175.342.478'], ['G01.374.661', 'G02.111.490'], ['F01.145.632', 'G11.427.410.698'], ['A08.186.211.200.885.287.249.487.775.500'], ['D02.092.311.342.478.650... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical, in silico, and experimental evidence for pathogenicity of two novel splice site mutations in the SH3TC2 gene. | Charcot-Marie-Tooth (CMT) neuropathy is the most common inherited neuromuscular disorder. CMT is genetically very heterogeneous. Mutations in the SH3TC2 gene cause Charcot-Marie-Tooth neuropathy type 4C (CMT4C), a demyelinating form with autosomal recessive inheritance. In this study, two novel splice site mutations in... | ['Adult', 'Animals', 'COS Cells', 'Charcot-Marie-Tooth Disease', 'Chlorocebus aethiops', 'Computer Simulation', 'Family Health', 'Female', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Male', 'Middle Aged', 'Mutation', 'Neural Conduction', 'Proteins', 'Reference Values', 'Transfection'] | 22,950,825 | [['M01.060.116'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['L01.224.160'], ['N01.400.300'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effect of constituting amino acid residue numbers on molecularly imprinted chiral recognition sites. | In the present study, the effect of constituting amino acid residue numbers of oligopeptide derivatives, which are candidate materials to construct molecular recognition sites, on chiral recognition ability was investigated. Chiral recognition sites were formed from oligopeptide derivatives, of which constituting amino... | ['Amino Acids', 'Molecular Conformation', 'Oligopeptides', 'Stereoisomerism', 'Tryptophan'] | 12,774,289 | [['D12.125'], ['G02.111.570.820'], ['D12.644.456'], ['G02.607.445.682'], ['D12.125.072.050.850', 'D12.125.142.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The ITALK project: a developmental robotics approach to the study of individual, social, and linguistic learning. | This article presents results from a multidisciplinary research project on the integration and transfer of language knowledge into robots as an empirical paradigm for the study of language development in both humans and humanoid robots. Within the framework of human linguistic and cognitive development, we focus on how... | ['Artificial Intelligence', 'Child Development', 'Cognition', 'Humans', 'Infant', 'Interpersonal Relations', 'Language', 'Learning', 'Linguistics', 'Robotics'] | 24,934,294 | [['G17.035.250', 'L01.224.050.375'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.401'], ['F01.145.209.399', 'L01.559'], ['F02.463.425', 'F02.784.629.529'], ['L01.559.598'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
Purification, identification, and characterization of methylcobalamin from Spirulina platensis. | The present study reports methylcobalamin in Spirulina platensis using high-performance liquid chromatography (HPLC), thin-layer chromatography (TLC), microbiological assay, chemiluminescence assay, liquid chromatography-mass spectrometry (LC-MS), and tandem mass spectrometry (MS/MS). Extraction of vitamin B12 from S. ... | ['Escherichia coli', 'Lactobacillus delbrueckii', 'Spirulina', 'Vitamin B 12', 'Vitamin B Complex'] | 20,799,700 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.353.750.450.475.250', 'B03.510.460.400.410.475.475.250', 'B03.510.550.450.475.250'], ['B03.280.697'], ['D03.383.129.578.840.437.777', 'D03.633.400.909.437.777', 'D04.345.783.437.777'], ['D27.505.696.494.600.708']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nutritional status has marginal influence on the metabolism of inorganic arsenic in pregnant Bangladeshi women. | BACKGROUND: The interindividual variation in metabolism of inorganic arsenic (iAs), involving methylation via one-carbon metabolism, has been well documented, but the reasons remain unclear.OBJECTIVES: In this population-based study we aimed to elucidate the effect of nutrition on As methylation among women in Matlab, ... | ['Adult', 'Arsenic', 'Arsenic Poisoning', 'Bangladesh', 'Body Mass Index', 'Chromatography, High Pressure Liquid', 'Female', 'Health Surveys', 'Humans', 'Malnutrition', 'Mass Spectrometry', 'Maternal Exposure', 'Methylation', 'Nutritional Status', 'Pregnancy', 'Water Pollutants, Chemical'] | 18,335,097 | [['M01.060.116'], ['D01.268.513.249'], ['C10.720.475.150', 'C25.723.098'], ['Z01.252.245.131'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.196.181.400.300'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Actions of glycogen synthase and phosphorylase of rabbit-skeletal muscle on modified glycogens. | The high reactivities exhibited by rabbit-muscle synthase and phosphorylase for unmodified glycogen-acceptors decrease progressively, presumably because of a large increase in apparent Km as the glycogen molecule is converted into its component maltosaccharide chains by the debranching enzyme, isoamylase. Elongation of... | ['Animals', 'Glycogen', 'Glycogen Synthase', 'Kinetics', 'Muscles', 'Phosphorylases', 'Rabbits', 'Substrate Specificity'] | 417,806 | [['B01.050'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D08.811.913.400.450.460.375'], ['G01.374.661', 'G02.111.490'], ['A02.633', 'A10.690'], ['D08.811.913.400.450.460.400'], ['B01.050.150.900.649.313.968.700'], ['G02.111.835']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Atmospheric pressure photoionization as a powerful tool for large-scale lipidomic studies. | Lipidomic studies often use liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS) for separation, identification, and quantification. However, due to the wide structural diversity of lipids, the most apolar part of the lipidome is often detected with low sensitivity in ESI. Atmospheric pressure (A... | ['Atmospheric Pressure', 'Computational Biology', 'Lipids', 'Photochemistry', 'Spectrometry, Mass, Electrospray Ionization', 'Triterpenes'] | 22,359,092 | [['G16.500.750.274', 'N06.230.300.100.185'], ['H01.158.273.180', 'L01.313.124'], ['D10'], ['H01.181.529.711'], ['E05.196.566.600'], ['D02.455.849.919']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Methadone treatment for HIV prevention-feasibility, retention, and predictors of attrition in Dar es Salaam, Tanzania: a retrospective cohort study. | BACKGROUND: People who inject drugs (PWID) in Dar es Salaam, Tanzania, have an estimated human immunodeficiency virus (HIV) prevalence of 42%-50% compared with 6.9% among the general population. Extensive evidence supports methadone maintenance to lower morbidity, mortality, and transmission of HIV and other infectious... | ['Adult', 'Cohort Studies', 'Female', 'HIV Infections', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Male', 'Medication Adherence', 'Methadone', 'Middle Aged', 'Opiate Substitution Treatment', 'Retrospective Studies', 'Tanzania', 'Young Adult'] | 24,855,149 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A possible auditory basis for internal structure of phonetic categories. | We used a selective adaptation procedure to investigate the possibility that differences in the degree to which stimuli within a phonetic category are considered to be good exemplars of the category--that is, differences in perceived category goodness--have a basis at a prephonetic, auditory level of processing. For th... | ['Adaptation, Physiological', 'Humans', 'Phonetics', 'Sound Spectrography', 'Speech Acoustics', 'Speech Perception'] | 6,875,098 | [['G07.025', 'G16.012.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.518'], ['E05.855'], ['G11.561.812.650', 'G11.561.820'], ['F02.463.593.071.875', 'G07.888.125.875']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5. | Transcriptional regulation of proteins involved in neuronal polarity is a key process that underlies the ability of neurons to transfer information in the central nervous system. The Collapsin Response Mediator Protein (CRMP) family is best known for its role in neurite outgrowth regulation conducting to neuronal polar... | ['Amidohydrolases', 'Animals', 'Binding Sites', 'Brain', 'Cell Line, Tumor', 'Gene Expression Regulation', 'Humans', 'Hydrolases', 'Mice', 'Microtubule-Associated Proteins', 'Mutation', 'Neurites', 'Neuronal Outgrowth', 'Neurons', 'Promoter Regions, Genetic', 'Protein Binding', 'SOXD Transcription Factors'] | 28,864,883 | [['D08.811.277.087'], ['B01.050'], ['G02.111.570.120'], ['A08.186.211'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.220.600.450', 'D12.776.631.560'], ['G05.365.590'], ['A08.675.256.500', 'A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quenching of Hoechst 33258 fluorescence in erythroid precursors. | Quenching of the fluorescence of DNA-bound Hoechst 33258 in erythroid precursors was studied by flow cytometry and cytochemistry. This quenching artifact may affect the measurement of ploidy in specific cases. The bone marrow cells of two patients with hemolytic disease and active erythropoiesis contained subpopulation... | ['Benzimidazoles', 'Bisbenzimidazole', 'Bone Marrow Cells', 'Erythroid Precursor Cells', 'Flow Cytometry', 'Fluorescence', 'Hemoglobins', 'Humans'] | 1,696,537 | [['D03.633.100.103'], ['D03.633.100.103.145'], ['A11.148', 'A15.378.316'], ['A11.148.378.590.837.250', 'A11.443.240.497', 'A11.872.378.590.817.250', 'A15.378.316.378.590.837.250'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.24... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of arcobacter species in drinking water, spring water, and raw milk as determined by multiplex PCR. | The aim of this study was to investigate the incidence of Arcobacter species in water sources and raw milk from healthy animals in Kayseri, Turkey. A total of 175 samples of drinking water (n = 100), spring water (n = 25), and raw milk (n = 50) were examined. Arcobacter species were isolated using the membrane filtrati... | ['Animals', 'Arcobacter', 'Cattle', 'Food Contamination', 'Fresh Water', 'Humans', 'Milk', 'Polymerase Chain Reaction', 'Prevalence', 'Turkey', 'Water Microbiology'] | 21,219,725 | [['B01.050'], ['B03.440.050', 'B03.660.150.050'], ['B01.050.150.900.649.313.500.380.271'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['G16.500.275.280', 'N06.230.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', ... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Distribution of omega-6 and omega-3 polyunsaturated fatty acids in the whole rat body and 25 compartments. | The steady state compositions of omega-6 and omega-3 polyunsaturated fatty acids (PUFA) throughout the various viscera and tissues within the whole body of rats have not previously been described in a comprehensive manner. Dams consumed diets containing 10wt% fat (15% linoleate and 3% á-linolenate). Male offspring (n=9... | ['Animal Feed', 'Animals', 'Dietary Fats', 'Fatty Acids, Omega-3', 'Fatty Acids, Omega-6', 'Female', 'Male', 'Rats, Long-Evans'] | 26,120,061 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['D10.251.355.343'], ['B01.050.150.900.649.313.992.635.505.700.500']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fatigue and tensile properties of radicular dentin substrate. | The purpose of this study was to compare the fatigue and tensile strengths of radicular dentin. Forty bovine lower central incisors were used, twenty teeth for the fatigue test and twenty teeth for the tensile test. Bovine teeth were each sectioned into coronal and radicular portions. Dentin slabs of 1mm thickness were... | ['Animals', 'Anisotropy', 'Cattle', 'Dentin', 'In Vitro Techniques', 'Incisor', 'Stress, Mechanical', 'Tensile Strength'] | 21,146,824 | [['B01.050'], ['G01.590.040', 'G02.050'], ['B01.050.150.900.649.313.500.380.271'], ['A14.549.167.900.280'], ['E05.481'], ['A14.549.167.860.425'], ['G01.374.835'], ['G01.374.850']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Berberine inhibits fluphenazine-induced up-regulation of CDR1 in Candida albicans. | Over-expression of the Candida drug resistance gene CDR1 is a common mechanism generating azole-resistant Candida albicans in clinical isolates. CDR1 is transcriptionally activated through the binding of the transcription factor Tac1p to the cis-acting drug-responsive element (DRE) in its promoter. We previously demons... | ['Antifungal Agents', 'Berberine', 'Candida albicans', 'Drug Resistance, Fungal', 'Drug Synergism', 'Fluphenazine', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Membrane Transport Proteins', 'Plant Extracts', 'RNA, Messenger', 'Transcriptional Activation', 'Up-Regulation'] | 24,492,724 | [['D27.505.954.122.136'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['G06.225.383', 'G07.690.773.984.269.383'], ['G07.690.773.968.477'], ['D02.886.369.326', 'D03.633.300.783.326'], ['D12.776.354'], ['G05.308.330'], ['D12.776.157.530', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acquired von Willebrand's syndrome and Ehlers-Danlos syndrome presenting with gastro-intestinal bleeding. | The clinical and laboratory findings in a patient with severe gastro-intestinal bleeding and the Ehlers-Danlos syndrome are described. Coagulation studies and a lack of history of previous haemorrhage were consistent with a diagnosis of acquired von Willebrand's syndrome. His response to treatment with blood transfusio... | ['Aged', 'Blood Coagulation Tests', 'Ehlers-Danlos Syndrome', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Male', 'Pedigree', 'von Willebrand Diseases'] | 314,153 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overall accessibility to traveling by rail for the elderly with and without functional limitations: the whole-trip perspective. | Elderly persons' perceived accessibility to railway traveling depends on their functional limitations/diseases, their functional abilities and their travel behaviors in interaction with the barriers encountered during whole trips. A survey was conducted on a random sample of 1000 city residents (65-85 years old; 57% re... | ['Aged', 'Aged, 80 and over', 'Architectural Accessibility', 'Attitude', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Railroads', 'Surveys and Questionnaires', 'Sweden', 'Travel'] | 25,514,149 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['J01.086.339.070'], ['F01.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.937.690'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Treatment of Prinzmetal's angina with normal coronary vessels by thoracic sympathectomy]. | Two cases of Prinzmetal angina with normal coronary arteries are reported: coronary spasm was demonstrated in the left anterior descending artery in the first, and in the right coronary artery in the second case. Invalidating angina persisted despite maximal medical treatment with nitrite derivatives, nifedipine, verap... | ['Adult', 'Angina Pectoris, Variant', 'Coronary Vasospasm', 'Female', 'Ganglia, Sympathetic', 'Heart', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Sympathectomy'] | 6,818,923 | [['M01.060.116'], ['C14.280.647.187.150.150', 'C14.907.585.187.150.500', 'C23.888.592.612.233.500.150.150'], ['C14.280.647.250.295', 'C14.907.585.250.295'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800.300'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Community innovation in hazardous materials management: progress in implementing SARA Title III in the United States. Superfund Amendments and Reauthorization Act. | Title III of the Superfund Amendments and Reauthorization Act (SARA Title III) established a new federal approach to managing toxic chemical hazards. This legislation required industry to disclose the type and quantity of such chemicals and also required the establishment of state and local government organizations to ... | ['Communication', 'Disaster Planning', 'Hazardous Substances', 'Humans', 'Industry', 'Information Services', 'Policy Making', 'Public Policy', 'Truth Disclosure', 'United States'] | 11,679,193 | [['F01.145.209', 'L01.143'], ['N06.230.100.035'], ['D27.888.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['L01.453'], ['N03.706.742'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['F01.829.401.046.800', 'I01.880.604.583.080.134.800'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Network target for screening synergistic drug combinations with application to traditional Chinese medicine. | BACKGROUND: Multicomponent therapeutics offer bright prospects for the control of complex diseases in a synergistic manner. However, finding ways to screen the synergistic combinations from numerous pharmacological agents is still an ongoing challenge.RESULTS: In this work, we proposed for the first time a "network tar... | ['Angiogenesis Inhibitors', 'Drug Evaluation, Preclinical', 'Drug Synergism', 'Humans', 'Medicine, Chinese Traditional', 'Molecular Sequence Annotation', 'Neovascularization, Pathologic', 'User-Computer Interface'] | 21,689,469 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['E05.290.750', 'E05.337.550'], ['G07.690.773.968.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['E05.393.760.479', 'L01.453.245.667.580'], ['C23.550.589.500'], ['L01.224.900... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Redefining Gold Standard Testing for Diagnosing Leptospirosis: Further Evidence from a Well-Characterized, Flood-Related Outbreak in Sri Lanka. | A gap in the leptospirosis field remains the lack of well-characterized sample collections that allow for comparison of new methods to standard ones. In the context of a flood-related outbreak of leptospirosis evaluated in Anuradhapura, Sri Lanka, a specimen bank was obtained with detailed metadata accompanied by gold ... | ['Adult', 'Agglutination Tests', 'Cross-Sectional Studies', 'Disease Outbreaks', 'Female', 'Foodborne Diseases', 'Humans', 'Leptospirosis', 'Male', 'Polymerase Chain Reaction', 'Sri Lanka'] | 27,402,521 | [['M01.060.116'], ['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.290'], ['C25.723.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.794.511'], ['E05.393.620.500'], ['Z01.252.245.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Binding of Hoechst 33258 and 4',6'-diamidino-2-phenylindole to self-complementary decadeoxynucleotides with modified exocyclic base substituents. | Fluorescence titrations have been carried out to determine the association constants (Ka) for binding of the dyes Hoechst 33258 and DAPI to the self-complementary decamer d(CTGAATTCAG) and nine duplex derivatives with exocyclic substituent changes in the six central base pairs. Many Ka values are in the range (2-5) x 1... | ['2-Aminopurine', 'Adenine', 'Base Composition', 'Base Sequence', 'Bisbenzimidazole', 'Fluorescent Dyes', 'Indoles', 'Kinetics', 'Models, Molecular', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Oligodeoxyribonucleotides'] | 1,703,013 | [['D03.633.100.759.138.050'], ['D03.633.100.759.138'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.633.100.103.145'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D03.633.100.473'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.570.820.486', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Exploration of the benefits of an activity-specific test of temperament. | The Structure of Temperament Questionnaire (STQ) was proposed by Rusalov in 1989 and subsequently tested in five languages. The questionnaire assesses four temperamental traits (Ergonicity, Plasticity, Tempo, and Emotionality) in three separate areas of activity: physical, verbal-social, and intellectual. The scales ar... | ['Adolescent', 'Adult', 'Arousal', 'Emotions', 'Female', 'Humans', 'Individuality', 'Inhibition, Psychological', 'Male', 'Motor Activity', 'Personality Assessment', 'Personality Inventory', 'Psychometrics', 'Reproducibility of Results', 'Sex Factors', 'Temperament', 'Young Adult'] | 19,928,626 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F01.145.632', 'G11.427.410.698'], ['F04.513'], ['F04.711.647.513'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of the activities of DNA primase-polymerase alpha complex from KB cells by hexasodium sym-bis(m-aminobenzoyl-m-amino-p-methylbenzoyl-1-naphthylamino-4 ,6,8-trisulfonate)carbamide. | A trypanocidal drug suramin [hexasodium sym-bis(m-amino-benzoyl-m-amino-p-methylbenzoyl-1-naphthylamino-4, 6, 8-trisulfonate)carbamide] was found to be a potent inhibitor of the activities of DNA primase and polymerase alpha from human KB cells. The mechanism of the inhibition by suramin was, however, quite different b... | ['Binding, Competitive', 'DNA Polymerase II', 'DNA Primase', 'Humans', 'KB Cells', 'Kinetics', 'Nucleic Acid Synthesis Inhibitors', 'RNA Nucleotidyltransferases', 'Suramin'] | 4,088,877 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D08.811.913.696.445.308.300.230'], ['D08.811.913.696.445.735.270.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.400.500', 'A11.251.860.180.400.500', 'A11.436.340.500'], ['G01.374.661', 'G02.111.490'], ['D27.505.519.389.675'], ['D08.811... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gain of the human dura in vivo and its effects on invasive brain signal feature detection. | Invasive brain signal recordings generally rely on bioelectrodes implanted on the cortex underneath the dura. Subdural recordings have strong advantages in terms of bandwidth, spatial resolution and signal quality. However, subdural electrodes also have the drawback of compromising the long-term stability of such impla... | ['Algorithms', 'Brain', 'Cerebral Cortex', 'Data Interpretation, Statistical', 'Dura Mater', 'Electrocardiography', 'Electrodes, Implanted', 'Electroencephalography', 'Electrophysiology', 'Epidural Space', 'Epilepsy', 'Equipment Design', 'Humans', 'Image Processing, Computer-Assisted', 'Individuality', 'Mastoid', 'Moto... | 20,109,492 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['A08.186.566.395'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.376.300', 'E01.370.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Electroencephalographic abnormalities in infants with hypoplastic left heart syndrome. | Electroencephalography (EEG) was performed on 16 neonates between 38-45 weeks conceptional age with hypoplastic left heart syndrome (HLHS). The findings were compared blindly with EEGs recorded from 16 infants with other congenital heart defects and 15 infants referred for EEGs with noncardiac diagnoses or problems. EE... | ['Aorta', 'Electroencephalography', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Infant, Newborn', 'Sleep Stages'] | 2,712,948 | [['A07.015.114.056'], ['E01.370.376.300', 'E01.370.405.245'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['F02.830.855.796', 'G11.561.803.754']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association between hyper-pronated foot and the degree of severity of disability in patients with non-specific low back pain. | BACKGROUND: It has been established that Hyper-pronation of the foot may lead to postural changes in the lower limbs, with a resultant pelvic ante-version, and a subsequent risk of development of low back pain. However, the association between the presence of a hyper-pronated foot and the severity of disability in low ... | ['Adult', 'Female', 'Foot', 'Humans', 'Low Back Pain', 'Lower Extremity', 'Male', 'Middle Aged', 'Pain Measurement', 'Pronation', 'Severity of Illness Index', 'Weight-Bearing'] | 30,100,309 | [['M01.060.116'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['A01.378.610'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['G11.427.410.698.840'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Hypertension and peripheral arterial hemodynamics]. | Sixty uncomplicated hypertensive patients (40 stable and 20 borderline) were studied, by strain gauge plethysmography, in comparison with 25 normotensive subjects, in order to evaluate the arterial hemodynamics of the lower limbs in essential hypertension and to verify the different pattern in borderline and in stable ... | ['Aged', 'Arteries', 'Female', 'Hemodynamics', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Regional Blood Flow', 'Vascular Resistance'] | 9,273,469 | [['M01.060.116.100'], ['A07.015.114'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['G09.330.100.780'], ['G09.330.380.921']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Bacteriocinogenic typing of lactobacilli]. | Sensitivity of 588 strains of Lactobacilli belonging to 15 species was studied with respect to 39 bacteriocinogenic strains of Lactobacilli producing 39 variants of bacteriocins. The study provided a set of 20 indicator strains of Lactobacilli. With the use of this set it is possible to mark Lactobacilli of various spe... | ['Bacteriocins', 'Bacteriological Techniques', 'Lactobacillus', 'Lactobacillus acidophilus', 'Lactobacillus casei'] | 6,816,143 | [['D12.776.097.151', 'D12.776.543.695.110'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['B03.353.750.450.475.100', 'B03.510.460.400.410.475.475.100', 'B03.510.550.450.475.100'], ['B03.353.750.450.475.225', 'B03.510.460.400.410.475.475.225'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mark tests for mirror self-recognition in capuchin monkeys (Cebus apella) trained to touch marks. | In Experiment 1, three capuchin monkeys (Cebus apella) were exposed to a mirror in their home cage for 3 days and then given food treats for touching orange marks located on the surface of an experimental chamber. Following training, a mirror was added to the chamber to see if the monkeys would use it to guide non-rein... | ['Animals', 'Behavior, Animal', 'Cebus', 'Male', 'Recognition, Psychology', 'Visual Perception'] | 17,253,635 | [['B01.050'], ['F01.145.113'], ['B01.050.150.900.649.313.988.400.600.150.170.120'], ['F02.463.425.540.706'], ['F02.463.593.932']] | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
White matter alteration in a patient with Graves' disease. | A case of Graves' disease with white matter abnormalities is presented here. The diagnosis as Graves' disease was made when the patient was 5 years old, and a subtotal thyroidectomy was performed when she was 10. Her neurological symptoms began at age 19 with paresthesia of her legs and lower body. Cranial magnetic res... | ['Adult', 'Brain', 'Demyelinating Autoimmune Diseases, CNS', 'Disease Progression', 'Female', 'Glatiramer Acetate', 'Graves Disease', 'Humans', 'Immunosuppressive Agents', 'Magnetic Resonance Imaging', 'Nerve Fibers, Myelinated', 'Optic Neuritis', 'Paresthesia', 'Peptides', 'Spinal Cord', 'Steroids', 'Thyroid Gland', '... | 17,890,414 | [['M01.060.116'], ['A08.186.211'], ['C10.114.375', 'C10.228.140.695.562', 'C10.314.350', 'C20.111.258.250'], ['C23.550.291.656'], ['D12.644.219'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E01.370.350.825.500'], ... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lack of a nocturnal rise of serum melatonin in prepubertal gilts. | Experiments were conducted to determine if a nocturnal rise in serum melatonin occurs in prepubertal gilts and whether acute exposure of gilts to light during the dark period abruptly reduces serum concentrations of melatonin. In experiment 1, 12 prepubertal crossbred gilts (Duroc x Hampshire x Chester White x Yorkshir... | ['Animals', 'Circadian Rhythm', 'Darkness', 'Female', 'Light', 'Melatonin', 'Random Allocation', 'Swine'] | 1,617,960 | [['B01.050'], ['G07.180.562.190'], ['G01.590.540.233'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D03.633.100.473.914.481', 'D06.472.506'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Activation of group II metabotropic glutamate receptors induces depotentiation in amygdala slices and reduces fear-potentiated startle in rats. | There is a close correlation between long-term potentiation (LTP) in the synapses of lateral amygdala (LA) and fear conditioning in animals. We predict that reversal of LTP (depotentiation) in this area of the brain may ameliorate conditioned fear. Activation of group II metabotropic glutamate receptors (mGluR II) with... | ['Amygdala', 'Animals', 'Conditioning, Classical', 'Cyclopropanes', 'Excitatory Amino Acid Agonists', 'Excitatory Postsynaptic Potentials', 'Fear', 'Glycine', 'In Vitro Techniques', 'Long-Term Synaptic Depression', 'Male', 'Memory', 'Microinjections', 'Patch-Clamp Techniques', 'Rats', 'Rats, Sprague-Dawley', 'Receptors... | 15,774,944 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['F02.463.425.179.308'], ['D02.455.426.392.368.533'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['F01.470.361'], ['D12.... | ['Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cortical sources of the auditory attentional blink. | Attentional blink (AB) refers to the situation where correctly identifying a target impairs the processing of a subsequent probe in a sequence of stimuli. Although the AB often coincides with a modulation of scalp-recorded cognitive event-related potentials (ERPs), the neural sources of this effect remain unclear. In t... | ['Acoustic Stimulation', 'Adolescent', 'Adult', 'Attentional Blink', 'Auditory Perception', 'Brain', 'Electroencephalography', 'Evoked Potentials, Auditory', 'Female', 'Humans', 'Male', 'Young Adult'] | 29,742,026 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.116'], ['F02.463.593.932.145'], ['F02.463.593.071', 'G07.888.125'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.06... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antihypertensive effects of perindopril treatment in adult spontaneously hypertensive rats. | OBJECTIVE: To determine the effect of perindopril treatment and treatment withdrawal in the prevention of hypertension in adult male spontaneously hypertensive rats (SHR).ANIMALS AND METHODS: Beginning at 15 weeks of age, male SHR were treated with either distilled water (control) or different daily dosages of perindop... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Dose-Response Relationship, Drug', 'Hypertension', 'Indoles', 'Male', 'Norepinephrine', 'Peptidyl-Dipeptidase A', 'Perindopril', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Time Factors'] | 9,343,032 | [['D27.505.519.389.745.085'], ['B01.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.875', 'G07.690.936.500'], ['C14.907.489'], ['D03.633.100.473'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['D08... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preliminary evaluation of variable compliance joystick for people with multiple sclerosis. | Upper-limb fatigue is a common problem that may restrict people with multiple sclerosis (MS) from using their electric powered wheelchair effectively and for a long period of time. The objective of this research is to evaluate whether participants with MS can drive better using a variable compliance joystick (VCJ) and ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Equipment Design', 'Ergonomics', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Psychomotor Performance', 'Software', 'Task Performance and Analysis', 'User-Computer Interface', 'Wheelchairs', 'Young Adult'] | 25,356,558 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['E05.320'], ['F02.784.412', 'J01.293.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F02.808', 'G11.427.700', 'G11.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Localization and excision of occult breast lesions. | Between 1976 and 1982, 190 non-palpable mammographic abnormalities considered to be suspicious of malignancy were excised using a needle localization technique. The indications for biopsy, technique for localization, method for confirmation of excision and histopathological preparation are presented. The histopathologi... | ['Adult', 'Breast Neoplasms', 'Calcinosis', 'Female', 'Humans', 'Mammography', 'Middle Aged', 'Needles', 'Nipples', 'Palpation'] | 6,626,923 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['M01.060.116.630'], ['E07.612'], ['A01.236.500'], ['E01.370.600.600']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Controlling cost escalation of healthcare: making universal health coverage sustainable in China. | An increasingly number of low- and middle-income countries have developed and implemented a national policy towards universal coverage of healthcare for their citizens over the past decade. Among them is China which has expanded its population coverage by health insurance from around 29.7% in 2003 to over 90% at the en... | ['China', 'Cost Control', 'Delivery of Health Care', 'Humans', 'Universal Health Insurance'] | 22,992,484 | [['Z01.252.474.164'], ['N03.219.151.160'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.265.500']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP. | Interleukin-7 (IL-7), a cytokine produced by stromal cells, is required for thymic development and peripheral homeostasis of most major subsets of T cells. We examined whether regulatory T (Treg) cells also required the IL-7 pathway by analyzing IL-7Ralpha(-/-) mice. We observed a striking reduction in cells with the T... | ['Animals', 'Cell Membrane', 'Cell Separation', 'Cytokines', 'Female', 'Gene Deletion', 'Interleukin-7', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Phenotype', 'Receptors, Interleukin-7', 'T-Lymphocytes, Regulatory', 'Thymus Gland'] | 18,664,628 | [['B01.050'], ['A11.284.149'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D12.644.276.374.465.246', 'D12.776.467.374.465.224', 'D23.529.374.465.246'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: implication for carcinogenesis. | One apparent feature of cancerous cells is genomic instability, which may include various types of chromosomal aberrations, such as translocation, aneuploidy, and the presence of micronuclei inside the cells. Mutagenic factors that promote the emergence of genomic instability are recognized as risk factors for the deve... | ['Areca', 'Arecoline', 'Carcinogens', 'Cell Line, Tumor', 'Cell Transformation, Neoplastic', 'Cells, Cultured', 'Genomic Instability', 'Histones', 'Humans', 'Mitosis', 'Mouth Neoplasms', 'Prometaphase', 'Spindle Apparatus', 'Tumor Suppressor Protein p53'] | 20,138,568 | [['B01.650.940.800.575.912.250.093.088'], ['D03.066.515.292', 'D03.132.080', 'D03.383.725.547.292'], ['D27.888.569.100'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.251'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.77... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers. | BACKGROUND & AIMS: Exercise is an important component of obesity-associated disorders and has been shown to reduce markers of nonalcoholic fatty liver disease (NAFLD). However, little is known about how these effects are influenced by alcohol intake. The authors performed a randomized controlled trial to investigate th... | ['Adult', 'Aged', 'Alcohol Drinking', 'Anthropometry', 'Body Composition', 'Exercise', 'Female', 'Humans', 'Liver', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Obesity', 'Plethysmography', 'Prospective Studies', 'Triglycerides', 'United Kingdom'] | 28,501,537 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.317.269'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C18.654.726.500'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geog... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pre- and postoperative correlation of patient-reported outcome measures with standardized Timed Up and Go (TUG) test results in lumbar degenerative disc disease. | BACKGROUND: The Timed Up and Go (TUG) test is a reliable tool for evaluating objective functional impairment (OFI) in patients with degenerative disc disease before a surgical intervention. The aim of this study is to assess the validity of the TUG test to measure change in function postoperatively.METHODS: In a prospe... | ['Adult', 'Aged', 'Decompression, Surgical', 'Diskectomy', 'Female', 'Humans', 'Intervertebral Disc Degeneration', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Patient Reported Outcome Measures', 'Postoperative Complications', 'Prospective Studies', 'Quality of Life', 'Spinal Stenosis'] | 27,488,842 | [['M01.060.116'], ['M01.060.116.100'], ['E04.188'], ['E02.718.444', 'E04.188.350', 'E04.555.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.153'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E05.318.308.980.344.500', 'N03.349.380.210.750', 'N04.761.559.590.399.875', 'N05.425.210.500', 'N05.715... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Aberrant expression of Beclin-1 and LC3 correlates with poor prognosis of human hypopharyngeal squamous cell carcinoma. | BACKGROUND: Beclin-1, a key regulator of autophagy. Microtubule-associated protein 1 light chain 3 (LC3), is involved in autophagsome formation during autophagy. The autophagic genes beclin-1 and LC3 paly an important role in the development and progression of tumor. This study was designed to investigate the expressio... | ['Aged', 'Apoptosis Regulatory Proteins', 'Beclin-1', 'Carcinoma, Squamous Cell', 'Female', 'Gene Expression', 'Humans', 'Hypopharyngeal Neoplasms', 'Hypopharynx', 'Lymphatic Metastasis', 'Male', 'Membrane Proteins', 'Microtubule-Associated Proteins', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'Survival Analy... | 23,935,917 | [['M01.060.116.100'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.644.360.075.335', 'D12.776.094.500', 'D12.776.476.075.335'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.48... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Skewed X chromosome inactivation in fraternal female twins results in moderately severe and mild haemophilia B. | Female carriers of haemophilia B are usually asymptomatic; however, the disease resulting from different pathophysiological mechanisms has rarely been documented in females. In this study, we investigated the mechanisms responsible for haemophilia B in fraternal female twins. We sequenced the factor IX gene (F9) of the... | ['Blotting, Southern', 'Diseases in Twins', 'Factor IX', 'Female', 'Haplotypes', 'Hemophilia B', 'Humans', 'Infant', 'Mutation, Missense', 'Pedigree', 'Polymerase Chain Reaction', 'Twins, Dizygotic', 'X Chromosome Inactivation'] | 18,540,891 | [['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['C23.550.291.750'], ['D08.622.355', 'D12.776.124.125.375', 'D12.776.811.243.355', 'D23.119.375'], ['G05.380.360'], ['C15.378.100.100.510', 'C15.378.100.141.510', 'C15.378.463.510', 'C16.320.099.510', 'C16.320.322.235'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Open reduction and internal fixation of radial head fractures associated with olecranon fracture or dislocation. | Six fracture dislocations or dislocations of the olecranon associated with radial head fractures were treated with open reduction and internal fixation of the radial head. The olecranon was reduced and if fractured (three cases) was internally fixed. Postoperatively, early active range of motion was achieved in all cas... | ['Adolescent', 'Adult', 'Aged', 'Elbow Joint', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Humans', 'Joint Dislocations', 'Male', 'Middle Aged', 'Physical Therapy Modalities', 'Radius Fractures', 'Ulna Fractures'] | 3,506,584 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A02.835.583.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['M01.060.116.630'], ['E02.779', 'E02.831.535'], ['C26... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of detergent washing powders on minimal eliciting patch test concentrations of nickel and chromium. | Minimum eliciting levels of nickel have been estimated in 25 nickel-sensitive subjects, and of chromium in 14 chromium-sensitive subjects by patch tests with aqueous solutions of the respective metals. The minimum level of each metal required to provoke a patch test reaction was considerably greater than that found in ... | ['Chlorides', 'Chromates', 'Chromium', 'Chromium Compounds', 'Dermatitis, Contact', 'Detergents', 'Eczema', 'Edetic Acid', 'Female', 'Hand Dermatoses', 'Humans', 'Male', 'Nickel', 'Patch Tests', 'Potassium Dichromate', 'Sodium Dodecyl Sulfate', 'Surface-Active Agents', 'Water'] | 6,418,438 | [['D01.210.450.150', 'D01.248.497.158.215'], ['D01.220.150', 'D01.248.497.158.235'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.220'], ['C17.800.174.255', 'C17.800.815.255'], ['D27.720.877.265', 'J01.516.381'], ['C17.800.174.620', 'C17.800.815.620'], ['D02.092.782.258.368.250', 'D02.241.081.018.25... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
An analysis of unsuccessful teleconsultations. | Over six years, 4317 teleconsultations were scheduled in the Arizona Telemedicine Program. A total of 402 scheduled teleconsultations (9.3%) did not take place. A review showed that 254 were cancelled but eventually took place (5.9%), while 148 never took place (3.4%). The cost of a teleconsultation to the service prov... | ['Adult', 'Arizona', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Professional-Patient Relations', 'Psychiatry', 'Remote Consultation', 'Treatment Refusal'] | 15,006,208 | [['M01.060.116'], ['Z01.107.567.875.760.100'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650', 'N05.300.660'], ['F04.096.544', 'H02.403.690'], ['L01.178.847.652.550', 'N04.452.758.849.550', 'N04.590.374.800.550'], ['F01.100.150.750.750', 'F01.145.488.887.750', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
The fate of Notch-deficient nephrogenic progenitor cells during metanephric kidney development. | To determine which nephron segments require Notch signals for development, we conditionally deleted Rbpj, a transcription factor required for canonical Notch signaling, in nephrogenic progenitors (NPs) of the metanephric mesenchyme. The retinoic acid receptor-â2 (Rarb2) promoter efficiently directed Cre-recombinase (Cr... | ['Animals', 'Apoptosis', 'Cell Proliferation', 'Immunoglobulin J Recombination Signal Sequence-Binding Protein', 'Kidney', 'Mice', 'Nephrons', 'Receptors, Notch', 'Receptors, Retinoic Acid', 'Signal Transduction', 'Stem Cells'] | 21,270,765 | [['B01.050'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.260.457', 'D12.776.660.486', 'D12.776.930.327'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['A05.810.453.736'], ['D12.776.543.750.725', 'D12.776.930.770'], ['D12.776.826.701', 'D12.776.930.775'], ['G02.111.820', 'G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamics of hnRNPs and omega speckles in normal and heat shocked live cell nuclei of Drosophila melanogaster. | The nucleus limited long-noncoding hsrù-n transcripts, hnRNPs, and some other RNA processing proteins organize nucleoplasmic omega speckles in Drosophila. Unlike other nuclear speckles, omega speckles rapidly disappear following cell stress, while hnRNPs and other associated proteins move away from chromosome sites, nu... | ['Animals', 'Cell Nucleus', 'Drosophila melanogaster', 'Heterogeneous-Nuclear Ribonucleoproteins', 'Hot Temperature'] | 25,663,367 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D12.776.157.725.813.750', 'D12.776.664.962.813.750'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An inflammatory myofibroblastic tumor in the transplanted liver displaying quick wash-in and wash-out on contrast-enhanced ultrasound: A case report. | RATIONALE: Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal neoplasm, and its presence in a grafted liver is exceedingly rare.PATIENT CONCERNS: A 54-year-old woman was admitted to our hospital with a half-month history of intermittent melena. She had undergone deceased-donor liver transplantation (LT... | ['Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Liver Neoplasms', 'Liver Transplantation', 'Middle Aged', 'Neoplasms, Muscle Tissue'] | 29,245,287 | [['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['C04.557.450.590']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The localization of the supraorbital notch or foramen is crucial for headache and supraorbital neuralgia avoiding and treatment. | The aim of this study was to provide the morphological and morphometric data of the supraorbital foramina or notches related to sex, side, and the climatic conditions where the population lived. It was hypothesized that the distribution of the occurrence and location of these openings depends on climatic conditions in ... | ['Climate', 'Female', 'Foramen Magnum', 'Headache', 'Humans', 'Male', 'Neuralgia', 'Orbit', 'Treatment Outcome'] | 22,807,312 | [['G16.500.275.071', 'N06.230.300.100.250'], ['A02.835.232.781.572.434'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.600', 'C23.888.592.612.664'], ['A02.835.232.781.324.690'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A case of relapse with drug-susceptible M. leprae after multidrug therapy. | A male born in 1930 was diagnosed as smear-positive borderline leprosy in 1971, and was treated with dapsone and/or sulfamethoxypyridazine from 1972 to 1980 with clinical improvement. However, new skin lesions with smears strongly positive appeared in August 1980, and he was diagnosed as having downgraded to lepromatou... | ['Adult', 'Dapsone', 'Drug Therapy, Combination', 'Humans', 'Leprosy, Borderline', 'Leprosy, Lepromatous', 'Male', 'Mycobacterium leprae', 'Prothionamide', 'Recurrence', 'Rifampin', 'Sulfamethoxypyridazine'] | 2,071,981 | [['M01.060.116'], ['D02.886.590.263'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.040.552.475.371.850.249'], ['C01.150.252.410.040.552.475.371.775.500'], ['B03.510.024.962.500.502', 'B03.510.460.400.410.552.552.502'], ['D03.066.349.570', 'D03.383.725.394.675'], ['C23.550.291.937... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lobar attenuation difference of the liver on computed tomography. | Lobar attenuation difference of the liver was demonstrated by computed tomography (CT) in 16 cases among over 1,000 cases in which CT scans of the liver were obtained. Cases were divided into two groups: with liver tumor and without liver tumor. Among the former group, hepatocellular carcinomas is the predominant lesio... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Female', 'Humans', 'Liver', 'Liver Diseases', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Portal Vein', 'Thrombosis', 'Tomography, X-Ray Computed'] | 6,272,353 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C06.552'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['A07.015.908.670.567'], ['C14.907.355.830']... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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