Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Neonatal plasma vitamin K1 levels following oral and intramuscular administration of vitamin K1. | Vitamin K1 levels were measured by high performance liquid chromatography in cord blood (n = 33) and at the age of 97-120 h after administration of 2 mg of vitamin K1 orally (n = 88) or 1 mg of vitamin K1 by im injection (n = 88). Vitamin K1 levels were less than 0.05 micrograms/l in cord blood. The mean (range), SEM, ... | ['Administration, Oral', 'Chromatography, High Pressure Liquid', 'Fetal Blood', 'Humans', 'Infant, Newborn', 'Injections, Intramuscular', 'Vitamin K 1', 'Vitamin K Deficiency Bleeding'] | 8,193,487 | [['E02.319.267.100'], ['E05.196.181.400.300'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E02.319.267.530.460'], ['D02.455.426.559.847.638.721.374.689', 'D02.455.849.291.523.500.689', 'D02.806.550.625', 'D04.615.638.721.374.689'], ['C15.378... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Objective and subjective outcomes in surgery for chronic sinusitis. | Endoscopic and radiological findings in patients with chronic sinusitis do not always correlate with symptoms. Studies suggest that postoperative endoscopic examination of the sinonasal cavity provides prognostic information regarding the potential for future episodes of sinusitis and the need for revision surgery. It ... | ['Chronic Disease', 'Endoscopy', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Nasal Cavity', 'Outcome Assessment, Health Care', 'Paranasal Sinuses', 'Patient Satisfaction', 'Postoperative Care', 'Prognosis', 'Prospective Studies', 'Radiography', 'Recurrence', 'Reoperation', 'Reproducibility of Results', 'Sinusitis'] | 10,718,412 | [['C23.550.291.500'], ['E01.370.388.250', 'E04.502.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.449'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['A04.531.621'], ['F01.10... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Production of platelet-rich plasma gel from elderly patients under antithrombotic drugs: Perspectives in chronic wounds care. | Platelet-Rich Plasma (PRP) is an autologous biological therapy obtained by centrifuging the patient's own blood to concentrate platelets. The addition of autologous thrombin and calcium chloride to PRP allows the production of a semi-solid form called PRP gel. PRP gel is increasingly used in a variety of tissue defects... | ['Adult', 'Chronic Disease', 'Female', 'Fibrinolytic Agents', 'Humans', 'Male', 'Middle Aged', 'Platelet-Rich Plasma', 'Thrombin', 'Wound Healing'] | 28,805,478 | [['M01.060.116'], ['C23.550.291.500'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A12.207.152.693.600', 'A12.207.270.695.600', 'A15.145.693.600'], ['D08.811.277.656.300.760.855', 'D08.811.277.656.959.350.855', 'D12.776.1... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Determination of the individual changes in cardiovascular system reactivity in prescribing adrenergic blockaders]. | The changes occurring in hemodynamics due to the effect of alpha-adreno-blocking agent pyrroxan and beta-blocking agent obzidan were studied in 20 patients with neurocirculatory dystonia and in 20 patients with stage IIB hypertensive disease. Forty healthy persons formed the control group. The results of the investigat... | ['Adrenergic alpha-Antagonists', 'Adrenergic beta-Antagonists', 'Adult', 'Cardiovascular System', 'Clinical Trials as Topic', 'Dose-Response Relationship, Drug', 'Drug Evaluation', 'Hemodynamics', 'Humans', 'Hypertension', 'Middle Aged', 'Myocardial Contraction', 'Neurocirculatory Asthenia', 'Physical Exertion', 'Postu... | 23,449 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['A07'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.625', 'E05.337.425'], ['G09.330.380'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Child homicide by parents in Chile: a gender-based study and analysis of post-filicide attempted suicide. | INTRODUCTION: The victimization of children has attracted considerable attention over the years. Some authors conceptualize child murder as an intra-familial phenomenon. Over the last 40 years, extensive literature has suggested that there are differences between neonaticide and infanticide, and differential characteri... | ['Adolescent', 'Adult', 'Chile', 'Criminals', 'Databases, Factual', 'Fathers', 'Female', 'Forensic Psychiatry', 'Humans', 'Infant', 'Infanticide', 'Logistic Models', 'Male', 'Middle Aged', 'Mothers', 'Sex Factors', 'Suicide, Attempted', 'Young Adult'] | 23,192,006 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.235'], ['M01.142'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['F04.096.544.335', 'H02.403.690.208', 'I01.198.780.937.469', 'I01.880.604.583.310', 'N03.706.535.351'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Intervention in time-processing ability, daily time management and autonomy in children with intellectual disabilities aged 10-17 years - A cluster randomised trial. | BACKGROUND/AIM: Difficulties with management of time are frequently observed in children and youth with intellectual disabilities (IDs). The aim of this study was to evaluate a new intervention programme 'My Time' to improve time-processing ability (TPA) in children with IDs aged 10-17 years (n = 61).METHODS: Cluster r... | ['Adolescent', 'Child', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Occupational Therapy', 'Perception', 'Personal Autonomy', 'Severity of Illness Index', 'Time Factors', 'Time Management'] | 30,548,268 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['F02.463.593'], ['F02.600', 'I01.880.604.473.380.500', 'K01.752.566.479.830.650', 'N03.706.437.380.500... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Phenomena and Processes ... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation. | The formin homology protein mDia is a Rho GTPase effector protein that participates in stress fiber formation, cytokinesis, and transcriptional activation of the serum response factor. Although the function of another effector of Rho, Rho-associated kinase, is well established, relatively little is known about the func... | ['3T3 Cells', 'Adaptor Proteins, Signal Transducing', 'Animals', 'COS Cells', 'Carrier Proteins', 'DNA, Complementary', 'Formins', 'GRB2 Adaptor Protein', 'Glutathione Transferase', 'HeLa Cells', 'Humans', 'Immunoblotting', 'Mice', 'Microscopy, Fluorescence', 'Molecular Sequence Data', 'Plasmids', 'Precipitin Tests', '... | 11,509,578 | [['A11.251.210.100', 'A11.329.228.100'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.776.157'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D05.750.078.730.333', 'D12.776.220.525.333'], ['D12.644.360.024.2... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nitrogen conversion under rapid pyrolysis of two types of aquatic biomass and corresponding blends with coal. | Rapid pyrolysis of two types of aquatic biomass (blue-green algae and water hyacinth), and their blends with two coals (bituminous and anthracite) was carried out in a high-frequency furnace. Nitrogen conversions during rapid pyrolysis of the two biomass and the interactions between the biomass and coals on nitrogen co... | ['Aquatic Organisms', 'Biomass', 'Biotechnology', 'Coal', 'Cyanobacteria', 'Eichhornia', 'Elements', 'Hot Temperature', 'Lignin', 'Nitrogen', 'Polysaccharides'] | 21,903,383 | [['B05.080', 'G16.500.275.725.500.650.075'], ['G16.500.275.157.100', 'N06.230.124.100'], ['H01.158.550', 'J01.897.120'], ['D20.345.108', 'N06.230.132.258.108'], ['B03.280', 'B03.440.475.100'], ['B01.650.940.800.575.912.250.827.500'], ['D01.268'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Crystallization and preliminary crystallographic studies of juvenile hormone-binding protein from Galleria mellonella haemolymph. | Juvenile hormone-binding protein (JHBP) isolated from Galleria mellonella haemolymph has been crystallized using the hanging-drop method in two polymorphic forms. The best diffracting crystals (2.7 A) are trigonal, space group P3(1)21 (or P3(2)21), with unit-cell parameters a = 110.4, c = 93.9 A. X-ray diffraction data... | ['Animals', 'Carrier Proteins', 'Crystallization', 'Crystallography, X-Ray', 'Hemolymph', 'Indicators and Reagents', 'Insect Proteins', 'Lepidoptera'] | 12,595,713 | [['B01.050'], ['D12.776.157'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['A13.453'], ['D27.720.470.410'], ['D12.776.093.500'], ['B01.050.500.131.617.720.500.500.937']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain-derived neurotrophic factor concentrations in tetraplegic athletes. | STUDY DESIGN: A prospective cohort with acute tetraplegia.OBJECTIVE: The purpose of this study was to investigate acute changes in serum brain-derived neurotrophic factor (BDNF) concentrations in tetraplegic spinal cord-injured (SCI) athletes during a typical training session of wheelchair rugby.SETTINGS: German Sport ... | ['Adult', 'Brain-Derived Neurotrophic Factor', 'Cohort Studies', 'Enzyme-Linked Immunosorbent Assay', 'Exercise', 'Female', 'Heart Rate', 'Humans', 'Lactic Acid', 'Male', 'Middle Aged', 'Quadriplegia', 'Spinal Cord Injuries', 'Wheelchairs'] | 26,078,232 | [['M01.060.116'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['G11.427.410.69... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparative study of hydroquinone-free and hydroquinone-based hyperpigmentation regimens in treating facial hyperpigmentation and photoaging. | BACKGROUND: Photoaged skin, characterized by mottled, irregular areas of pigmentation, is a common skin condition that is often difficult to treat. The areas of hypermelanosis are an aesthetic concern to subjects and may lead to social distress and quality of life issues. There are many commercial hyperpigmentation reg... | ['Administration, Cutaneous', 'Adult', 'Dermatologic Agents', 'Female', 'Follow-Up Studies', 'Humans', 'Hydroquinones', 'Hyperpigmentation', 'Middle Aged', 'Patient Satisfaction', 'Single-Blind Method', 'Skin Aging', 'Skin Pigmentation', 'Surveys and Questionnaires', 'Time Factors'] | 23,545,931 | [['E02.319.267.120.060'], ['M01.060.116'], ['D27.505.954.444'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.657.393'], ['C17.800.621.430'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unfavorable, complex, and monosomal karyotypes: the most challenging forms of acute myeloid leukemia. | In acute myeloid leukemia, the karyotype of the leukemic cell is the most powerful predictor of treatment outcome. Approximately 30% of cases of AML have an unfavorable karyotype, and if treated with conventional chemotherapy, a complete response rate of about 50% and a 5-year overall survival of 10% to 20% are expecte... | ['Abnormal Karyotype', 'Chromosome Aberrations', 'Humans', 'Leukemia, Myeloid, Acute', 'Prognosis', 'Survival Rate'] | 22,957,403 | [['C23.550.210.024', 'G05.360.162.679.500', 'G05.365.590.175.024'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['E01.789'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850.520.308.985.550.900']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Annexin A5 promotes macrophage activation and contributes to pulmonary fibrosis induced by silica particles. | OBJECTIVE: To investigate the contributions and underlying molecular mechanisms of annexin A5 toward silica-induced pulmonary fibrosis.METHODS: Male C57BL/6 mice were randomly divided into three groups and instilled intratracheally with silica, saline, or air. Mice were euthanized at 3, 7, 14, or 28 days following trea... | ['Air Pollutants', 'Animals', 'Annexin A5', 'Cytokines', 'Disease Models, Animal', 'Fas Ligand Protein', 'Lung', 'Macrophage Activation', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Particulate Matter', 'Pulmonary Fibrosis', 'RAW 264.7 Cells', 'RNA Interference', 'Random Allocation', 'Respiratory Mucosa', 'Si... | 25,757,482 | [['D27.888.284.101'], ['B01.050'], ['D12.776.157.125.050.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.374.750.249', 'D12.776.543.550.312', 'D23.529.374.750.249'], ['A04.411'], ['G12.287.500'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mutants with altered Ca2+-channel properties in Paramecium tetraurelia: isolation, characterization and genetic analysis. | Dancers are a group of mutants in Paramecium tetraurelia whose Ca2+ current inactivates poorly and are likely to be defective in the structure of their Ca2+ channels. These mutants show prolonged backward swimming in response to K+ and Ba2+ in the medium and were selected by this property in a galvanotactic trough. The... | ['Barium', 'Electrophysiology', 'Epistasis, Genetic', 'Genetic Complementation Test', 'Ion Channels', 'Microbiological Techniques', 'Movement', 'Paramecium', 'Potassium'] | 6,094,305 | [['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['H01.158.344.528', 'H01.158.782.236'], ['G05.308.207'], ['E05.393.281.526'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['E01.370.225.875', 'E05.200.875'], ['G07.568', 'G11.427.410'], ['B01.043.185.650.375.550.63... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. | Cultures of human mammary epithelial cells (HMECs) contain a subpopulation of variant cells with the capacity to propagate beyond an in vitro proliferation barrier. These variant HMECs, which contain hypermethylated and silenced p16(INK4a) (p16) promoters, eventually accumulate multiple chromosomal changes, many of whi... | ['Breast', 'Cells, Cultured', 'Cyclin-Dependent Kinase Inhibitor p16', 'DNA Methylation', 'Epithelial Cells', 'Female', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Promoter Regions, Genetic'] | 12,670,910 | [['A01.236'], ['A11.251'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma lactate concentrations in septic peritonitis: A retrospective study of 83 dogs (2007-2012). | OBJECTIVE: To determine if absolute plasma lactate concentration or lactate clearance in dogs with septic peritonitis is associated with morbidity or mortality.DESIGN: Retrospective cohort study from 2007 to 2012.SETTING: University teaching hospital.ANIMALS: Eighty-three dogs with septic peritonitis were included. Pat... | ['Animals', 'Biomarkers', 'Cohort Studies', 'Critical Care', 'Dog Diseases', 'Dogs', 'Female', 'Lactic Acid', 'Male', 'Peritonitis', 'Postoperative Complications', 'Prognosis', 'Retrospective Studies', 'Sensitivity and Specificity', 'Shock, Septic', 'Veterinary Medicine'] | 25,212,787 | [['B01.050'], ['D23.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.760.190', 'N02.421.585.190'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.241.511.459.450'], ['C01.463.600', 'C06.844.640'], ['C23.550.767'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Feeding practices of dog breeders in the United States and Canada. | OBJECTIVE: To determine the proportion of dog breeders who fed diets meeting the Association of American Feed Control Officials regulations for nutritional adequacy for reproduction and growth and to investigate factors that influenced feeding practices of breeders.DESIGN: Web-based cross-sectional survey.SAMPLE: 2,067... | ['Animal Feed', 'Animal Husbandry', 'Animals', 'Canada', 'Data Collection', 'Diet', 'Dogs', 'Female', 'Male', 'Surveys and Questionnaires', 'United States', 'Veterinarians'] | 25,181,271 | [['G07.203.300.300.100', 'J02.500.300.100'], ['J01.040.090'], ['B01.050'], ['Z01.107.567.176'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['G07.203.650.240'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.107.567.875'], ... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
[A rare cause of pulmonary arterial hypertension diagnosed in an elderly patient]. | Pulmonary arterial hypertension (PAH) is a rare and incurable disease, related to right ventricle overload and failure, which are late consequences of asymptomatic progressive pulmonary vascular occlusion. The clinical approach requires: a high clinical suspicion; the detection and confirmation of PAH by echo-Doppler a... | ['Aged', 'Cardiac Catheterization', 'Diagnosis, Differential', 'Echocardiography, Transesophageal', 'Eisenmenger Complex', 'Familial Primary Pulmonary Hypertension', 'Heart Atria', 'Heart Failure', 'Heart Septal Defects, Atrial', 'Heart Ventricles', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Prognosis', 'Pulmonary V... | 21,058,470 | [['M01.060.116.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.171'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['C14.240.400.450', 'C14.280.400.450', 'C16.131.240.400.450'], ['C08.381.423.300'], ['A07.541.358'], ['C14.280.434'], ['C14.240.400.560.375', 'C14.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Addition of test components during neurodynamic testing: effect on range of motion and sensory responses. | STUDY DESIGN: Single session, repeated-measures design.OBJECTIVES: To analyze the impact of different components of the neural tissue provocation test for the median nerve (NTPT1) on the range of motion (ROM) of the elbow and wrist and the sensory responses elicited by the test.BACKGROUND: The assessment of minor perip... | ['Adult', 'Analysis of Variance', 'Elbow', 'Humans', 'Male', 'Neurologic Examination', 'Psychomotor Performance', 'Range of Motion, Articular', 'Reference Values', 'Reproducibility of Results', 'Wrist'] | 11,352,189 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A01.378.800.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.376.550', 'E01.370.600.550'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E01.370.600.700', 'G11.427.760'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The topography of three-dimensional exploration: a new quantification of vertical and horizontal exploration, postural support, and exploratory bouts in the cylinder test. | The study of exploratory behavior in confined spaces can provide insights into both the spatial and the motor behavior of animals. In the present study, the behavior of rats placed inside of a cylinder (the cylinder test) for 5 min was examined to uncover: (1) the overall organization of exploratory behavior, (2) patte... | ['Animals', 'Electromyography', 'Exploratory Behavior', 'Female', 'Hindlimb', 'Male', 'Movement', 'Orientation', 'Posture', 'Psychomotor Performance', 'Rats', 'Reaction Time', 'Space Perception', 'Spatial Behavior', 'Species Specificity', 'Video Recording'] | 15,084,428 | [['B01.050'], ['E01.370.405.255', 'E01.370.530.255'], ['F01.145.387', 'F01.658.370'], ['A13.473'], ['G07.568', 'G11.427.410'], ['F01.058.577', 'F02.830.606'], ['G11.427.695'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Highly Selective Bioconversion of Ginsenoside Rb1 to Compound K by the Mycelium of Cordyceps sinensis under Optimized Conditions. | Compound K (CK), a highly active and bioavailable derivative obtained from protopanaxadiol ginsenosides, displays a wide variety of pharmacological properties, especially antitumor activity. However, the inadequacy of natural sources limits its application in the pharmaceutical industry. In this study, we firstly disco... | ['Biotransformation', 'Cordyceps', 'Culture Media', 'Ginsenosides', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Metabolic Networks and Pathways', 'Mycelium'] | 26,512,632 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['B01.300.107.501.220'], ['D27.720.470.305', 'E07.206'], ['D02.455.849.919.277', 'D09.408.782.300'], ['G02.300'], ['G02.380'], ['G03.493'], ['A19.687']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis of linkage-specific sialoside substrates for colorimetric assay of neuraminidases. | Neuraminidase substrates suitable for analysis of linkage specificity were enzymically synthesized in good yield by linking N-acetylneuraminic acid (Neup5Ac) to O-6 and O-3 of 4-nitrophenyl beta-D-galactopyranoside with beta-D-galactoside-alpha-(2----6)-sialyltransferase and beta-D-galactoside-alpha-(2----3)-sialyltran... | ['Bacteria', 'Colorimetry', 'Neuraminidase', 'Sialic Acids', 'Sialyltransferases', 'Substrate Specificity', 'Viruses'] | 1,802,382 | [['B03'], ['E05.196.922.250'], ['D08.811.277.450.692'], ['D02.241.081.844.562.668', 'D02.241.511.902.562.668', 'D09.067.687.668', 'D09.811.589.668'], ['D08.811.913.400.800'], ['G02.111.835'], ['B04']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Comparison of the efficacy of two H2 antagonists of histamine in allergic rhinitis. Considerations on the mechanism of action]. | A random study has been made on perennial atopic rhinitis patients divided into two homogeneous groups and treated with HH2 antagonists of different chemical structure: Cimetidine and Ranitidine. An identity of clinical and humoral results was noted in the two groups. This leads us to believe that the effects induced b... | ['Adolescent', 'Adult', 'Cimetidine', 'Female', 'Histamine H2 Antagonists', 'Humans', 'Immunoglobulin E', 'Male', 'Random Allocation', 'Ranitidine', 'Rhinitis, Allergic, Perennial', 'T-Lymphocytes, Regulatory'] | 2,899,413 | [['M01.060.057'], ['M01.060.116'], ['D02.078.370.200', 'D03.383.129.308.130'], ['D27.505.519.625.375.425.425', 'D27.505.696.577.375.425.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['E05.318.370.700', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Involvement of histamine receptors in SAPK/JNK phosphorylation. | Histamine is a mediator of inflammation in allergic disease and asthma. Stress activated protein kinases/c-jun N-terminal kinases (SAPK/JNK) are involved in asthma. This study examined the role of histamine receptors on the phosphorylation of SAPK/JNK in splenocytes. C57BL/6 mice splenocytes were treated with histamine... | ['Animals', 'Betahistine', 'Female', 'Histamine', 'Histamine Agonists', 'Histamine Antagonists', 'In Vitro Techniques', 'MAP Kinase Signaling System', 'Methylhistamines', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Phosphorylation', 'Receptors, G-Protein-Coupled', 'Receptors, Histamine', 'Receptors, Histamine H3',... | 22,487,127 | [['B01.050'], ['D03.383.725.086'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['D27.505.519.625.375.400', 'D27.505.696.577.375.400'], ['D27.505.519.625.375.425', 'D27.505.696.577.375.425'], ['E05.481'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D02.092.211.215.501.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Detection of hereditary forms of diabetes mellitus based on catamnestic data gathered over a period of many years]. | The paper is concerned with an analysis of examination of 414 relatives of the 1st-3rd degree of relationship in 230 families of probands with diabetes mellitus of different types. The frequency of detection of insulin dependent diabetes mellitus (IDDM) among relatives of the 1st degree of relationship in the families ... | ['Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Male', 'Time Factors'] | 3,422,941 | [['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G01.910.857']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hydrogen-bonding properties of galanthamine: an investigation through crystallographic database observations and computational chemistry. | The hydrogen-bonding properties of galanthamine have been investigated experimentally from a thorough analysis of crystallographic data retrieved from the Protein Data Bank and Cambridge Structural Database databases and theoretically through ab initio [MP2/6-311++G(2d,p)] and density functional theory [MPWB1K/6-31++G(... | ['Animals', 'Computer Simulation', 'Crystallography, X-Ray', 'Databases, Protein', 'Galantamine', 'Hydrogen Bonding', 'Models, Chemical', 'Models, Molecular', 'Models, Theoretical', 'Molecular Conformation', 'Quaternary Ammonium Compounds', 'Software', 'Static Electricity', 'Thermodynamics', 'Torpedo'] | 18,490,824 | [['B01.050'], ['L01.224.160'], ['E05.196.309.742.225'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['D03.132.052.500', 'D03.633.100.079.525'], ['G02.282'], ['E05.599.495'], ['E05.599.595'], ['E05.599'], ['G02.111.570.820'], ['D01... | ['Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Complement activation by pulsed tunable dye laser in normal skin and hemangioma. | Pulsed tunable dye laser (577 nm) (PTDL) therapy induces hemoglobin coagulation and tissue necrosis, which is mainly limited to blood vessels. To define whether this treatment activates complement in normal skin and senile hemangioma, we analyzed complement deposition in blood vessels by immunofluorescence. C3 fragment... | ['Coloring Agents', 'Complement Activation', 'Complement C3', 'Complement C8', 'Complement C9', 'Complement Pathway, Alternative', 'Hemangioma', 'Humans', 'Laser Therapy', 'Skin', 'Skin Neoplasms'] | 2,313,114 | [['D27.720.233'], ['G12.274'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274.750'], ['D12.776.124.486.274.850'], ['G12.274.695'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['A17.815'], ['C04.588.805', 'C17.800.882']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells. | Myelin-associated glycoprotein (MAG) has been detected in Schwann cells prior to the onset of myelination, suggesting its functions in the initiation of myelination. However, transcriptional regulatory mechanisms of MAG remain to be elucidated. Here, we analyzed the promoter of the MAG gene by using luciferase reporter... | ['Animals', 'Carrier Proteins', 'Cells, Cultured', 'Coculture Techniques', 'Myelin Sheath', 'Myelin-Associated Glycoprotein', 'Neurons', 'Promoter Regions, Genetic', 'Protein Binding', 'Rats', 'Schwann Cells', 'Transcription, Genetic', 'Transcriptional Activation'] | 18,941,509 | [['B01.050'], ['D12.776.157'], ['A11.251'], ['E05.481.500.374'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149.165.600', 'A11.650.600.500', 'A11.650.800.500', 'A11.671.501.512.560', 'A11.671.514.553'], ['D12.776.395.550.570', 'D12.776.503.921.049', 'D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Habitat suitability and movement corridors of grey wolf (Canis lupus) in Northern Pakistan. | Habitat suitability models are useful to understand species distribution and to guide management and conservation strategies. The grey wolf (Canis lupus) has been extirpated from most of its historic range in Pakistan primarily due to its impact on livestock and livelihoods. We used non-invasive survey data from camera... | ['Animals', 'Ecosystem', 'Geography', 'Models, Theoretical', 'Movement', 'Pakistan', 'Photography', 'Reproducibility of Results', 'Wolves'] | 29,121,089 | [['B01.050'], ['G16.500.275.157', 'N06.230.124'], ['H01.277.500'], ['E05.599'], ['G07.568', 'G11.427.410'], ['Z01.252.245.723'], ['E01.370.350.600', 'E05.712'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['B01.050.150.900.649.313.750.250.216.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Thin basement membrane syndrome in adults. | Eight (two men, six women) cases of adult thin basement membrane syndrome were studied to clarify the clinicopathological characteristics of the disease. The average age at the time of biopsy was 40 years. All the patients had persistent microscopic haematuria, normal renal function, and normal blood pressure, with the... | ['Adolescent', 'Adult', 'Basement Membrane', 'Blood Pressure', 'Follow-Up Studies', 'Hematuria', 'Humans', 'Kidney Glomerulus', 'Microscopy, Electron', 'Middle Aged', 'Proteinuria', 'Syndrome'] | 3,558,866 | [['M01.060.057'], ['M01.060.116'], ['A10.272.220', 'A10.615.179'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
What is the role of invasive monitoring procedures in the management of the critically ill? | In summary, therefore, to effectively apply invasive methods and beneficially use data derived from these procedures, it is essential that physicians have an understanding of the pathophysiology of ischemic heart disease and power failure, and of other situations in cardiology including the management of the complex pr... | ['Acute Disease', 'Blood Gas Analysis', 'Blood Pressure Determination', 'Cardiac Catheterization', 'Cardiac Output', 'Electrocardiography', 'Hemodynamics', 'Humans', 'Hypertension', 'Monitoring, Physiologic', 'Myocardial Contraction', 'Myocardial Infarction', 'Pacemaker, Artificial', 'Pulmonary Circulation', 'Pulmonary... | 849,584 | [['C23.550.291.125'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E01.370.370.140', 'E01.370.600.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E01.370.370.380.240', 'E01.370.405.240'], ['G09.330.380'], ['B01.050.150.900.649.3... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myeloid and lymphoid chimerism after T-cell-depleted bone marrow transplantation: evaluation of conditioning regimens using the polymerase chain reaction to amplify human minisatellite regions of genomic DNA. | Determining both myeloid and lymphoid chimerism after T-cell-depleted allogeneic bone marrow transplantation (BMT) could be helpful in the understanding of the biology of engraftment and could provide a rational method of assessing the ability of different conditioning regimens to promote engraftment. We prospectively ... | ['Adolescent', 'Adult', 'Base Sequence', 'Bone Marrow', 'Bone Marrow Transplantation', 'Child', 'Chimera', 'Chromosome Mapping', 'DNA, Satellite', 'Female', 'Granulocytes', 'Histocompatibility Testing', 'Humans', 'Leukemia', 'Lymphocyte Depletion', 'Lymphocytes', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Oligo... | 1,467,526 | [['M01.060.057'], ['M01.060.116'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A15.382.216'], ['E02.095.147.725.040', 'E04.936.580.040'], ['M01.060.406'], ['B05.200'], ['E05.393.183'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Differences in skin carcinogenesis by methylnitrosourea between mice of several strains. | To compare the susceptibilities of the skin of different strains of mice to the carcinogenic effect of a directly acting alkylating agent, groups of 20 mice were treated twice a week with 25 microliters of a solution of methylnitrosourea in methanol. The solution was 0.04M and was applied to the shaved back of female B... | ['Animals', 'Disease Models, Animal', 'Female', 'Methylnitrosourea', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred Strains', 'Neoplasms, Experimental', 'Skin Neoplasms'] | 1,764,693 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.065.950.594.490', 'D02.654.692.480'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['C04.619'... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of fluorescein-labeled autologous leukocytes for examination of retinal circulation in humans. | PURPOSE: Increased leukocyte-endothelium interaction have been suggested as a phenomenon contributing to capillary occlusion and/or rupture of the blood-retina barrier during human retinal vascular diseases. This study was performed to evaluate if fluorescein-labeled autologous leukocytes (FLALs) can be used for examin... | ['Adult', 'Cell Adhesion Molecules', 'Contrast Media', 'Fluorescein', 'Humans', 'Leukocyte Count', 'Leukocytes', 'Microscopy, Confocal', 'Middle Aged', 'Ophthalmoscopy', 'Retinal Vessels'] | 11,035,537 | [['M01.060.116'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D27.505.259.500', 'D27.720.259'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Rhythmical contractile activity of amnion in embryogenesis of reptiles and birds]. | Rhythmical contractile activity of amnion accompanies development reptiles and birds in the course of the large part of embryogenesis. These rhythmical contractions are myogenic and spontaneous. The strength, frequency, and character of the amnion contractions change in embryogenesis in a regular way. This type of rhyt... | ['Amnion', 'Animals', 'Birds', 'Chick Embryo', 'Embryo, Nonmammalian', 'Embryonic Development', 'Motor Activity', 'Periodicity', 'Reptiles'] | 20,063,782 | [['A10.615.284.277', 'A16.254.750.277'], ['B01.050'], ['B01.050.150.900.248'], ['A13.350.150', 'A16.331.200'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['F01.145.632', 'G11.427.410.698'], ['G01.910.645', 'G07.180.562'], ['B01.050.150.900.833']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of methods for reducing false positives in the automated detection of clustered microcalcifications in mammograms. | Clustered microcalcifications are often the first sign of breast cancer in a mammogram. Nevertheless, all clustered microcalcifications are not found by an individual radiologist reading a mammogram. The use of a second reader may find those clusters of microcalcifications not found by the first reader, thereby improvi... | ['Breast Neoplasms', 'Calcinosis', 'False Positive Reactions', 'Female', 'Humans', 'Mammography', 'Observer Variation', 'Radiographic Image Interpretation, Computer-Assisted', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 9,725,141 | [['C04.588.180', 'C17.800.090.500'], ['C18.452.174.130'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E01.158.600.680', 'E01.370.350.350.700', 'E01.370.350.700.705', 'L01.313.500.750.100.15... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Role of heat shock protein DnaK in osmotic adaptation of Escherichia coli. | Escherichia coli can adapt and recover growth at high osmolarity. Adaptation requires the deplasmolysis of cells previously plasmolyzed by the fast efflux of water promoted by osmotic upshift. Deplasmolysis is essentially ensured by a net osmo-dependent influx of K+. The cellular content of the heat shock protein DnaK ... | ['Alleles', 'Bacterial Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Genes, Bacterial', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Kinetics', 'Mutation', 'Osmolar Concentration', 'Transduction, Genetic'] | 2,066,337 | [['G05.360.340.024.340.030'], ['D12.776.097'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D12.776.580.216.375'], ['D12.776.580.216'], ['G01.374.661', 'G02.111.490'], ['G05.365.590'], ['G02.640'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Amenorrhoea revealing an arteriovenous uterine malformation, and recovery of menses after embolization. | A case is reported of secondary amenorrhoea related to an arteriovenous malformation (AVM) successfully treated with embolization, with a recovery of menstrual cycles. A 28-year-old woman presented with secondary amenorrhoea as the only clinical symptom. Although she had an eugonadic status, there was no genital withdr... | ['Adult', 'Amenorrhea', 'Arteriovenous Malformations', 'Embolization, Therapeutic', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Menstrual Cycle', 'Recovery of Function', 'Ultrasonography, Doppler, Color', 'Uterus'] | 14,653,894 | [['M01.060.116'], ['C23.550.568.500'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G08.686.605'], ['G16.757'], ['E01.370.350.850.850.850.850'], ['A05.360.319.679']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Long-term response to etanercept monotherapy in moderate to severe psoriasis: assessment in daily practice by the maintenance of low values of PASI and BSA. | INTRODUCTION: Efficacy and safety profiles of etanercept have been proved in numerous clinical trials; however, efficacy is determined by means of PASI 75 and few studies consider the maintenance of long-term response. The aims of this study were to provide data on long-term response to etanercept monotherapy in daily ... | ['Adult', 'Drug Administration Schedule', 'Etanercept', 'Female', 'Humans', 'Immunoglobulin G', 'Immunosuppressive Agents', 'Maintenance Chemotherapy', 'Male', 'Middle Aged', 'Psoriasis', 'Receptors, Tumor Necrosis Factor', 'Retrospective Studies', 'Time Factors', 'Treatment Outcome'] | 23,210,771 | [['M01.060.116'], ['E02.319.283'], ['D12.644.541.500.697.624', 'D12.776.124.486.485.538.500.624', 'D12.776.124.486.485.680.697.624', 'D12.776.124.790.651.538.500.624', 'D12.776.124.790.651.680.660.624', 'D12.776.377.715.548.538.500.624', 'D12.776.377.715.548.680.660.624', 'D12.776.543.750.705.852.760.232'], ['B01.050.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Testing putative causal associations of risk factors for early intercourse in the study of twin adults: genes and environment (STAGE). | Adverse childhood experiences and substance use have been identified as potential causal risk factors for early-onset sexual intercourse. While it is possible that exposure to these risk factors directly increases the likelihood of engaging in early intercourse, an alternative explanation is that observed associations ... | ['Adult', 'Coitus', 'Crime Victims', 'Female', 'Humans', 'Marijuana Abuse', 'Middle Aged', 'Risk Factors', 'Sexual Dysfunctions, Psychological', 'Smoking', 'Socioeconomic Factors', 'Substance-Related Disorders', 'Sweden', 'Young Adult'] | 22,441,771 | [['M01.060.116'], ['F01.145.802.188', 'G08.686.784.041'], ['M01.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775.635', 'F03.900.635'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['F03.835'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. | In the yeast Saccharomyces cerevisiae, the products of at least 14 genes are involved specifically in vesicular transport from the Golgi apparatus to the plasma membrane. Two of these genes, SEC8 and SEC15, encode components of a 1-2-million D multi-subunit complex that is found in the cytoplasm and associated with the... | ['Amino Acid Sequence', 'Carrier Proteins', 'Chromatography, Affinity', 'Fluorescent Antibody Technique', 'Fungal Proteins', 'GTP-Binding Proteins', 'Molecular Sequence Data', 'Molecular Weight', 'Mutagenesis, Site-Directed', 'Precipitin Tests', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Vesicula... | 7,615,633 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157'], ['E05.196.181.400.170'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['D12.776.354'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['L01.453.245.667'], ['G02.494'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mechanisms underlying the contractile response to endothelin-1 in the rat renal artery. | We assessed the functional response and the mechanisms following receptor stimulation of endothelin-1 (ET-1) in the rat renal artery. In this study, isometric tension was recorded in renal artery rings without endothelium. Cumulative application of ET-1 from 0.1 to 100 nmol/l induced a sustained concentration-dependent... | ['Animals', 'Calcium', 'Calcium Channels', 'Endothelin-1', 'In Vitro Techniques', 'Kidney', 'Male', 'Muscle, Smooth, Vascular', 'Rats', 'Rats, Wistar', 'Renal Artery', 'Vasoconstriction'] | 12,784,084 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['E05.481'], ['A05.810.453'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['B01.050.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tolerance to endotoxin prevents mortality in infected thermal injury: association with attenuated cytokine responses. | Endotoxin, a lipopolysaccharide (LPS), is a bacterial cell wall product instrumental in producing deleterious host responses to infection. This LPS appears to act, in part, by triggering release of endogenous mediators such as cytokines. Repeated exposures to endotoxin produce attenuated responses to this molecule. To ... | ['Acute-Phase Reaction', 'Animals', 'Burns', 'Eating', 'Endotoxins', 'Fibrinogen', 'Hematocrit', 'Interleukin-6', 'Leukocyte Count', 'Male', 'Rats', 'Rats, Inbred Strains', 'Tumor Necrosis Factor-alpha', 'Weight Gain', 'Wound Infection'] | 1,569,335 | [['C23.550.470.099'], ['B01.050'], ['C26.200'], ['G07.203.650.283', 'G10.261.330'], ['D23.946.123.329'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.46... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acceleration of lupus erythematosus-like processes by low frequency noise in the hybrid NZB/W mouse model. | INTRODUCTION: We investigated the effect of low frequency noise on the natural history of autoimmune diseases using hybrid New Zealand Black (NZB) and White (NZW) male mice that are prone to spontaneously develop systemic lupus erythematosus after 6 mo of age.METHODS: We exposed 3-mo-old mice to periods of low frequenc... | ['Animals', 'CD4-CD8 Ratio', 'Disease Models, Animal', 'Disease Progression', 'Lupus Erythematosus, Systemic', 'Lymphocyte Count', 'Lymphocyte Subsets', 'Male', 'Mice', 'Mice, Inbred NZB', 'Noise, Occupational', 'Occupational Diseases', 'Spleen', 'Vibration'] | 10,189,170 | [['B01.050'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E05.242.195.107.595.500.150.160', 'G04.140.107.595.500.150.160', 'G09.188.105.595.500.150.160', 'G12.248'], ['C22.232', 'E05.598.500', 'E05.599.395.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Surgery for Crohn's disease in childhood: influence of site of disease and operative procedure on outcome. | Factors influencing outcome after surgery have been studied in 67 children requiring bowel resection or diversion of the faecal stream for Crohn's disease. Patients were divided into four groups on the basis of disease location at time of surgery, and mean follow-up was 4.5 years. All three children with panenteric dis... | ['Adolescent', 'Cecum', 'Child', 'Child, Preschool', 'Colon', 'Crohn Disease', 'Female', 'Growth Disorders', 'Humans', 'Ileum', 'Intestines', 'Male', 'Prognosis', 'Retrospective Studies'] | 2,393,812 | [['M01.060.057'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['M01.060.406'], ['M01.060.406.448'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['C23.550.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['A03.556.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of starvation for exogenous carbon on functional mRNA stability and rate of peptide chain elongation in Escherichia coli. | The decay rate of the potential to synthesize proteins after complete inhibition of transcription by rifampicin was analyzed to determine the functional mRNA stability of exponentially growing and glucose-starved Escherichia coli B and K12 cells. We found the following: (i) The half-life of the mRNA pool increased 2.2-... | ['Carbon', 'Escherichia coli', 'Glucose', 'Half-Life', 'Peptide Chain Elongation, Translational', 'RNA, Messenger', 'Rifampin', 'Transcription, Genetic', 'beta-Galactosidase'] | 8,181,721 | [['D01.268.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D09.947.875.359.448'], ['G01.910.405'], ['G02.111.660.871.640', 'G03.734.871.640'], ['D13.444.735.544'], ['D03.633.400.811.700', 'D04.345.295.750.700'], ['G02.111.873', 'G05.297.700'], ['D08.811.277.450.410.100']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial. | BACKGROUND: Secondary progressive multiple sclerosis, for which no satisfactory treatment presently exists, accounts for most of the disability in patients with multiple sclerosis. Simvastatin, which is widely used for treatment of vascular disease, with its excellent safety profile, has immunomodulatory and neuroprote... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Atrophy', 'Brain', 'Cytokines', 'Disabled Persons', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Male', 'Middle Aged', 'Multiple Sclerosis, Chronic Progressive', 'Simvastatin', '... | 24,655,729 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.300.070'], ['A08.186.211'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['M01.150'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Attenuated noradrenaline-induced contraction of pulmonary arteries from rats treated with monocrotaline: role of rho kinase. | Noradrenaline-induced pulmonary artery contraction was reduced in monocrotaline-treated rats. The possibility that this could be due to alterations in the rho kinase pathway was examined in this study. A combination of nifedipine (10(-6) M) and thapsigargin (10(-6) M) attenuated noradrenaline-induced contraction signif... | ['Amides', 'Animals', 'Calcium', 'Drug Interactions', 'Enzyme Inhibitors', 'Hypertension, Pulmonary', 'Intracellular Signaling Peptides and Proteins', 'Male', 'Monocrotaline', 'Norepinephrine', 'Protein-Serine-Threonine Kinases', 'Pulmonary Artery', 'Pyridines', 'Rats', 'Vasoconstriction', 'Vasoconstrictor Agents', 'rh... | 16,127,279 | [['D02.065'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.690.773.968'], ['D27.505.519.389'], ['C08.381.423', 'C14.907.489.556'], ['D12.644.360', 'D12.776.476'], ['D03.132.716.500', 'D03.633.100.772.500'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
E-cadherin is a receptor for the common protein pneumococcal surface adhesin A (PsaA) of Streptococcus pneumoniae. | Streptococcus pneumoniae (Pnc) binds to nasopharyngeal (NP) epithelial cells in the first steps of nasopharyngeal carriage and colonization through bacterial adhesins. The pneumococcal surface adhesin A (PsaA) has previously been reported to play a significant role in pneumococcal adherence and colonization. Identifica... | ['Adhesins, Bacterial', 'Bacterial Adhesion', 'Cadherins', 'Calcium', 'Cell Line, Tumor', 'Edetic Acid', 'Epithelial Cells', 'Humans', 'Lipoproteins', 'Nasopharynx', 'Pneumococcal Infections', 'Streptococcus pneumoniae', 'Transfection'] | 17,412,553 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['G06.099.050'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['A11.436... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between IL-10 gene polymorphisms and susceptibility of tuberculosis: evidence based on a meta-analysis. | BACKGROUND: A number of observational studies have been conducted to investigate the association of IL-10 gene polymorphisms with tuberculosis (TB) susceptibility. However, the results of different studies were inconsistent. The aim of this study was to investigate the relationship between IL-10 -1082G/A, -819T/C, and ... | ['Genetic Predisposition to Disease', 'Humans', 'Interleukin-10', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'Tuberculosis'] | 24,523,896 | [['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['G05.365.795'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['C01.150.252.410.040.552.846']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alterations in atrial electrophysiology and tissue structure in a canine model of chronic atrial dilatation due to mitral regurgitation. | BACKGROUND: Clinically, chronic atrial dilatation is associated with an increased incidence of atrial fibrillation (AF), but the underlying mechanism is not clear. We have investigated atrial electrophysiology and tissue structure in a canine model of chronic atrial dilatation due to mitral regurgitation (MR).METHODS A... | ['Animals', 'Atrial Fibrillation', 'Chronic Disease', 'Dilatation, Pathologic', 'Disease Models, Animal', 'Disease Susceptibility', 'Dogs', 'Echocardiography, Transesophageal', 'Electrocardiography, Ambulatory', 'Electrophysiologic Techniques, Cardiac', 'Heart Atria', 'Heart Conduction System', 'Microscopy, Electron', ... | 12,732,604 | [['B01.050'], ['C14.280.067.198', 'C23.550.073.198'], ['C23.550.291.500'], ['C23.300.325'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.687', 'G07.100.250'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E01.370.370.380... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Comparison of the accuracy of 3-dimensional fusion algorithms]. | Recently many algorithms for matching three-dimensional medical data have been developed. Inter- and intramodal fusion of data adds valuable information for planning, controlling and evaluating therapies. This work presents a procedure to evaluate the accuracy of fusion algorithms by numerical means. In contrast to the... | ['Algorithms', 'Anisotropy', 'Artifacts', 'Brain', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Tomography, Emission-Computed'] | 12,465,257 | [['G17.035', 'L01.224.050'], ['G01.590.040', 'G02.050'], ['E05.047'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['E07.671'], ['E01.370.350.350.800', 'E01.370.350.600.350.800', 'E01.370.350.710.800', 'E01.370.350.82... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Clear Detection of Thin-Walled Regions in Unruptured Cerebral Aneurysms by Using Computational Fluid Dynamics. | OBJECTIVE: Thin-walled regions (TIWRs) within cerebral aneurysms have a high risk of rupture during surgical manipulation. Previous reports have demonstrated specific changes in the parameters of computational fluid dynamics in TIWRs; however, they have not been fully evaluated. We identified and investigated a novel p... | ['Computer Simulation', 'Female', 'Hemodynamics', 'Humans', 'Hydrodynamics', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Retrospective Studies', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 30,253,995 | [['L01.224.160'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.342'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.4... | ['Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The bleeding severity index: validation and comparison to other methods for classifying bleeding complications of medical therapy. | Reports of bleeding complications of medical therapy should be based on valid methods of classification, but the reproducibility of existing methods has not been tested. Therefore, we prospectively studied three methods to classify the severity of bleeding: a purely subjective implicit method, a previously published ex... | ['Anticoagulants', 'Blood Transfusion', 'Hemorrhage', 'Humans', 'Severity of Illness Index', 'Time Factors'] | 2,760,662 | [['D27.505.954.502.119'], ['E02.095.135'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Food intake patterns and cardiovascular risk factors in Japanese adults: analyses from the 2012 National Health and nutrition survey, Japan. | BACKGROUND: There is an increasing global interest in the role of Japanese diet as a possible explanation for the nation's healthy diet, which contributes to the world's highest life-expectancy enjoyed in Japan. However, nationwide studies on current food intake status among general Japanese population have not been es... | ['Adult', 'Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'Blood Pressure', 'Body Mass Index', 'Cardiovascular Diseases', 'Cholesterol', 'Cross-Sectional Studies', 'Diet, Healthy', 'Dietary Carbohydrates', 'Dietary Fats', 'Dietary Fiber', 'Dietary Proteins', 'Glycated Hemoglobin A', 'Humans', 'Japan', ... | 28,927,404 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.318.372... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Bedside nuclear medicine investigations in the intensive care unit. | The functional nature of nuclear medicine procedures makes them especially valuable in the management of patients undergoing intensive care. However, the severe nature of the patient's condition invariably prevents him or her from attending the nuclear medicine department for diagnostic investigations. We have piloted ... | ['Adult', 'Capillary Permeability', 'Enteral Nutrition', 'Female', 'Gastric Emptying', 'Humans', 'Imino Acids', 'Indium Radioisotopes', 'Intensive Care Units', 'Kidney Function Tests', 'Liver Failure', 'Liver Function Tests', 'Lung', 'Male', 'Microcomputers', 'Middle Aged', 'Nuclear Medicine', 'Organotechnetium Compoun... | 9,106,781 | [['M01.060.116'], ['G03.143.330', 'G09.330.165'], ['E02.421.360', 'E02.642.500.360'], ['G10.261.360.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.583', 'D02.491.485', 'D12.125.072.401'], ['D01.496.749.460'], ['N02.278.388.493'], ['E01.370.390.400'], ['C06.552.308.500'], ['E01.370.372.460'], ['A0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Re-expression of tumorigenicity after attenuation of human synaptotagmin 13 in a suppressed microcell hybrid cell line. | Human chromosome 11p11.2 contains a putative liver tumor suppressor locus that was identified using a microcell hybrid cell line-based model of tumor suppression. Transcription mapping of suppressed microcell hybrid cell lines suggests that human SYT13 represents a strong candidate for the 11p11.2 tumor suppressor gene... | ['Animals', 'Base Sequence', 'Cell Line, Tumor', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Genes, Tumor Suppressor', 'Humans', 'Hybrid Cells', 'Liver Neoplasms', 'Molecular Sequence Data', 'RNA Interference', 'Rats', 'Sequence Homology, Nucleic Acid', 'Synaptotagmins'] | 18,202,767 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.393.332'], ['G05.308.370'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.600'], ['C04.588.274.623', 'C06.301.623', 'C06.552... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Application of Ulva lactuca and Systoceira stricta algae-based activated carbons to hazardous cationic dyes removal from industrial effluents. | Marine algae Ulva lactuca (ULV-AC) and Systoceira stricta (SYS-AC) based activated carbons were investigated as potential adsorbents for the removal of hazardous cationic dyes. Both algae were surface oxidised by phosphoric acid for 2 and subsequently air activated at 600 °C for 3 h. Dyes adsorption parameters such as ... | ['Adsorption', 'Carbon', 'Charcoal', 'Coloring Agents', 'Hydrogen-Ion Concentration', 'Industrial Waste', 'Methylene Blue', 'Osmolar Concentration', 'Phaeophyta', 'Phenazines', 'Rosaniline Dyes', 'Spectroscopy, Fourier Transform Infrared', 'Temperature', 'Ulva', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 23,597,681 | [['G01.030', 'G02.020'], ['D01.268.150'], ['D01.268.150.150'], ['D27.720.233'], ['G02.300'], ['D20.944.420', 'N06.850.460.710.420'], ['D02.886.369.517', 'D03.633.300.783.517'], ['G02.640'], ['B01.750.600'], ['D03.633.300.704'], ['D02.092.146.755'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G01.906.595',... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Results of a trial with topotecan dose escalation and concurrent thoracic radiation therapy for locally advanced, inoperable nonsmall cell lung cancer. | PURPOSE: To conduct a dose escalation clinical study with topotecan and concurrent standard dose thoracic irradiation to assess its feasibility and toxicity in the treatment of patients with locally advanced, inoperable nonsmall cell lung cancer (NSCLCA).METHODS AND MATERIALS: Between April 1993 and August 1994, 12 pat... | ['Aged', 'Antineoplastic Agents', 'Camptothecin', 'Carcinoma, Non-Small-Cell Lung', 'Combined Modality Therapy', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Prospective Studies', 'Thorax', 'Topotecan'] | 8,985,046 | [['M01.060.116.100'], ['D27.505.954.248'], ['D03.132.151'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.71... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A report of 6 children with small bowel intussusception that required surgical intervention. | BACKGROUND/PURPOSE: We aim to justify the need for surgical intervention in our patients with childhood small bowel intussusceptions (SBIs) and review the current concepts in childhood SBI.MATERIALS AND METHODS: We retrospectively reviewed the clinical charts of all patients with surgically confirmed SBI between July 1... | ['Child', 'Child, Preschool', 'Female', 'Humans', 'Ileal Diseases', 'Infant', 'Intussusception', 'Jejunal Diseases', 'Male', 'Retrospective Studies'] | 16,567,200 | [['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.420'], ['M01.060.703'], ['C06.405.469.531.577'], ['C06.405.469.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', ... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunochemical detection of proteins and nucleic acids on filters using small luminescent inorganic crystals as markers. | A new luminescent marker for the immunochemical detection of proteins and nucleic acids on filters is reported. The label consists of inorganic crystals, generally called phosphors, with a particle size of 0.1-0.3 microns, stabilized in suspension with polycarboxylic acids and subsequently conjugated to immunoreactive ... | ['Alkaline Phosphatase', 'Blotting, Southern', 'Blotting, Western', 'Collodion', 'DNA', 'DNA Probes', 'Filtration', 'Luminescent Measurements', 'Nucleic Acid Hybridization', 'Proteins'] | 1,416,029 | [['D08.811.277.352.650.035'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D25.720.099.500.439', 'J01.637.051.720.099.500.439'], ['D13.444.308'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Early effects of gonadal steroids on the neuron number in the medial posterior region and the lateral division of the bed nucleus of the stria terminalis in the rat. | This work investigates the possible existence of sex differences in the number of neurons in the medial posterior region (BNSTMp) and the lateral division (BNSTL) of the bed nucleus of the stria terminalis in the rat. These two zones of the bed nucleus of the stria terminalis belong, respectively, to the vomeronasal sy... | ['Animals', 'Cell Count', 'Female', 'Frontal Lobe', 'Gonadal Steroid Hormones', 'Male', 'Orchiectomy', 'Rats', 'Rats, Inbred Strains', 'Sex Characteristics', 'Testosterone'] | 3,224,428 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A08.186.211.200.885.287.500.270'], ['D06.472.334.851'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adolescent contraceptive use: comparisons of male and female attitudes and information. | Information and attitudes about contraception and pregnancy were assessed with a self-administered questionnaire in a sample of urban Black teenagers. Data were obtained from 607 male and female students in high school health classes and a demographically similar group of 123 never-pregnant teenage women in a family pl... | ['Adolescent', 'African Americans', 'Contraception Behavior', 'Evaluation Studies as Topic', 'Family Planning Services', 'Female', 'Humans', 'Male', 'Pennsylvania', 'Practice, Psychological', 'School Health Services', 'Sex Education'] | 7,437,117 | [['M01.060.057'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F01.145.688.500', 'G08.686.784.891.500'], ['E05.337', 'N05.715.360.335'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.550', 'Z01.107.567.875.350.550', 'Z01.107.567.875.500.550'], ['F02.463.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Exclusive breast-feeding practice and associated factors in Enugu, Nigeria. | A cross-sectional questionnaire survey was conducted among 235 infant-mother pairs in five Baby Friendly pairs in five Baby Friendly Hospitals in Enugu-Nigeria in 1998. The aims were to study their breast-feeding practices and associated factors. The exclusive breast-feeding rate was 33.3% while the predominant breast-... | ['Adult', 'Breast Feeding', 'Chi-Square Distribution', 'Cross-Sectional Studies', 'Culture', 'Drinking', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Nigeria', 'Risk Factors'] | 12,081,350 | [['M01.060.116'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.076.201.450', 'I01.880.853.100'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Incidence of surgical site infections in the departments of orthopedics and traumatology]. | BACKGROUND/AIM: Besides infections of urinary tract and pneumonias, as well as blood infections, surgical site infections (SSI) represent one of the most common localization of hospital infections. The aim of this study was to determine the incidence of SSI in the departments of orthopedics and traumatology as well as ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Hospital Departments', 'Humans', 'Male', 'Middle Aged', 'Orthopedics', 'Surgical Wound Infection', 'Traumatology'] | 16,918,157 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['N02.278.216.500.968', 'N04.452.442.452.422'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.403.810.494'], ['C01.947.692', 'C23.550.767.925'], ['H02.403.810.850']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Integrated monitoring and information systems for managing aquatic invasive species in a changing climate. | Changes in temperature, precipitation, and other climatic drivers and sea-level rise will affect populations of existing native and non-native aquatic species and the vulnerability of aquatic environments to new invasions. Monitoring surveys provide the foundation for assessing the combined effects of climate change an... | ['Conservation of Natural Resources', 'Databases, Factual', 'Demography', 'Ecosystem', 'Environmental Monitoring', 'Greenhouse Effect', 'Models, Biological', 'Water'] | 18,577,087 | [['J01.256', 'N06.230.080'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.175.827', 'N06.230.265'], ['E05.599.395'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Acute poisoning admissions in one of the hospitals in Ankara. | Emergency service admissions at the Numune Hospital, Ankara, have been investigated for one year. Of the emergency admissions 5% were cases of poisoning; of these, 63.6% were due to drugs. | ['Acute Disease', 'Adolescent', 'Adult', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Poisoning', 'Sex Factors', 'Turkey'] | 4,007,896 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C25.723'], ['N05.715.350.675', 'N06.850.490.875'], ['Z01.252.245.500.850']] | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endothelial function is impaired after a high-salt meal in healthy subjects. | BACKGROUND: Dietary salt is related to blood pressure (BP), and cardiovascular disease and increased sodium intakes have been shown to impair vascular function. The effect of salt on endothelial function postprandially is unknown.OBJECTIVE: The aim was to investigate the postprandial effect of dietary salt on endotheli... | ['Adolescent', 'Adult', 'Aged', 'Australia', 'Blood Pressure', 'Brachial Artery', 'Diet, Sodium-Restricted', 'Endothelium, Vascular', 'Female', 'Humans', 'Hyperemia', 'Male', 'Manometry', 'Middle Aged', 'Postprandial Period', 'Severity of Illness Index', 'Sodium Chloride, Dietary', 'Young Adult'] | 21,228,265 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.139'], ['E02.642.249.290', 'G07.203.650.240.290'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.474'], ['E05.559'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Gaseous and Freely-Dissolved PCBs in the Lower Great Lakes Based on Passive Sampling: Spatial Trends and Air-Water Exchange. | Polyethylene passive sampling was performed to quantify gaseous and freely dissolved polychlorinated biphenyls (PCBs) in the air and water of Lakes Erie and Ontario during 2011-2012. In view of differing physical characteristics and the impacts of historical contamination by PCBs within these lakes, spatial variation o... | ['Air Pollutants', 'Canada', 'Environmental Monitoring', 'Gases', 'Great Lakes Region', 'Lakes', 'Polychlorinated Biphenyls', 'Water', 'Water Pollutants, Chemical'] | 26,642,083 | [['D27.888.284.101'], ['Z01.107.567.176'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.362'], ['Z01.107.567.875.350'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Serum platelet-activating factor acetylhydrolase and paraoxonase-1 activity in horses infected with Leptospira spp. | The aim of the study was to investigate the effect of infection with Leptospira spp. in horses on activities of platelet-activating factor acetylhydrolase (PAF-AH) and paraoxonase-1 (PON1) considering the anti-inflammatory/anti-oxidative properties of both enzymes. A total of 63 sport and leisure horses' sera were chos... | ['1-Alkyl-2-acetylglycerophosphocholine Esterase', 'Animals', 'Antibodies, Bacterial', 'Aryldialkylphosphatase', 'Croatia', 'Horse Diseases', 'Horses', 'Inflammation', 'Leptospira', 'Leptospirosis', 'Oxidative Stress', 'Serum'] | 21,414,286 | [['D08.811.277.352.100.680.750.937.249'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D08.811.277.352.660.500'], ['Z01.542.248.295'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C23.550.470'], ['B03.440.400.425.475.475', 'B03.851.475.475'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Concentrate minimization and water recovery enhancement using pellet precipitator in a reverse osmosis process treating textile wastewater. | Industrial wastewater reuse together with zero or near zero liquid discharges have been a growing trend due to the requirement of sustainable water management mandated by water scarcity and tightening discharge regulations. Studies have been conducted on the reclamation of textile industry wastewater using RO processes... | ['Filtration', 'Membranes, Artificial', 'Osmosis', 'Textile Industry', 'Waste Disposal, Fluid', 'Waste Water', 'Water', 'Water Purification'] | 29,894,945 | [['E05.196.454', 'G01.280', 'G02.263'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['J01.576.655.937'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865'], ['D01.045.250.875', 'D01.248.497.158.459.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Reduction laryngoplasty by external approach for glottic incompetence. Current role, demonstration of its efficacy by objective analysis of parameters of vocal quality]. | Authors talk about the place of surgical treatments with cervicotomy in abducted vocal cord, about the statistics of the department of Phoniatrics of the Hospital Edouard Herriot in Lyon. These techniques have actually a marginal place. But the analysis of a recent case shows us that endoscopic treatment for vocal fold... | ['Adult', 'Collagen', 'Female', 'Glottis', 'Humans', 'Injections', 'Laryngeal Diseases', 'Laryngoscopy', 'Male', 'Phonation', 'Polytetrafluoroethylene', 'Vocal Cords', 'Voice Disorders', 'Voice Quality'] | 1,444,086 | [['M01.060.116'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['C08.360', 'C09.400'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['G09.772.585'], ['D05.750.395.616', 'D25.720.395.616', 'J01.637.051.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Diagnostic Performance of a Cadmium-Zinc-Telluride Single-Photon Emission Computed Tomography System With Low-Dose Technetium-99m as Assessed by Fractional Flow Reserve. | BACKGROUND: Although stress single-photon emission computed tomography (SPECT) using a cadmium-zinc-telluride (CZT) camera facilitates radiation dose reduction, only a few studies have evaluated its diagnostic accuracy in Japanese patients by applying fractional flow reserve (FFR) measurements.METHODS AND RESULTS: We p... | ['Cadmium', 'Coronary Artery Disease', 'Coronary Stenosis', 'Fractional Flow Reserve, Myocardial', 'Humans', 'Prospective Studies', 'Radiopharmaceuticals', 'Sensitivity and Specificity', 'Technetium Tc 99m Sestamibi', 'Tellurium', 'Tomography, Emission-Computed, Single-Photon', 'Zinc'] | 27,053,432 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['G09.330.100.324.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. | Six galloyl-substituted procyanidin B1 and B2, 3-O-gallate, 3''-O-gallate, and 3,3''-di-O-gallate, were systematically synthesized with the condensation method using TMSOTf as a catalyst. Their ability of DPPH radical scavenging activity and DNA polymerase inhibitory activity were also investigated. The results indicat... | ['Animals', 'Biflavonoids', 'Biphenyl Compounds', 'Catalysis', 'Catechin', 'Cattle', 'Enzyme Inhibitors', 'Free Radical Scavengers', 'Gallic Acid', 'Molecular Conformation', 'Nucleic Acid Synthesis Inhibitors', 'Picrates', 'Proanthocyanidins', 'Rats', 'Structure-Activity Relationship'] | 15,781,387 | [['B01.050'], ['D03.383.663.283.266.450.190', 'D03.633.100.150.266.450.190'], ['D02.455.426.559.389.185'], ['G02.130'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['B01.050.150.900.649.313.500.380.271'], ['D27.505.519.389'], ['D27.505.519.217.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Prevalence of Culture Change Practice in US Nursing Homes: Findings From a 2016/2017 Nationwide Survey. | BACKGROUND AND OBJECTIVES: Given the dynamic nursing home (NH) industry and evolving regulatory environment, depiction of contemporary NH culture-change (person/resident-centered) care practice is of interest. Thus, we aimed to portray the 2016/2017 prevalence of NH culture change-related processes and structures and t... | ['Environment', 'Humans', 'Leadership', 'Medicaid', 'Nursing Homes', 'Organizational Culture', 'Power, Psychological', 'Quality of Health Care', 'Reimbursement, Incentive', 'Surveys and Questionnaires', 'United States'] | 30,234,764 | [['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['N03.219.521.346.506.564.655', 'N03.706.615.693'], ['N02.278.825.610'], ['N04.452.606'], ['F01.658.780'], ['N04.761', 'N05.715'], ['N03.219.521.710.305.380'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A comparison of antinociception induced by foot shock and morphine. | We compared the antinociception produced by brief intermittent foot shock (0.8-1.0 mA for 20 sec) and morphine by measuring the peak and duration of the effect, the consequences of spinalectomy and the sensitivity to antagonism by naloxone and d- and l-pentazocine and cyclazocine. Foot shock produced a peak antinocicep... | ['Animals', 'Cyclazocine', 'Electroshock', 'Foot', 'Male', 'Methadone', 'Morphine', 'Naloxone', 'Nociceptors', 'Pain', 'Pentazocine', 'Perception', 'Rats', 'Rats, Inbred Strains', 'Receptors, Opioid', 'Spinal Cord', 'Time Factors'] | 6,312,021 | [['B01.050'], ['D03.383.113.367', 'D03.605.168'], ['E05.723.402.403', 'F04.669.224'], ['A01.378.610.250'], ['D02.522.675'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.615.723.795.706'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular basis for the origin of differential spectral and binding profiles of dansylamide with human carbonic anhydrase I and II. | Sulfonamide derivatives serve as potent inhibitors of carbonic anhydrases (CAs), and a few such inhibitors have been currently used as drugs for the treatment of different pathogenic conditions in humans. In pursuit of designing the isozyme-specific inhibitors of human CAs, we observed that the fluorescence spectral pr... | ['Binding Sites', 'Carbonic Anhydrase I', 'Carbonic Anhydrase II', 'Dansyl Compounds', 'Fluorescent Dyes', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Ligands', 'Macromolecular Substances', 'Models, Chemical', 'Protein Binding', 'Spectrometry, Fluorescence', 'Structure-Activity Relationship', 'Thermodynamics'] | 15,751,944 | [['G02.111.570.120'], ['D08.811.520.241.300.150.100'], ['D08.811.520.241.300.150.200'], ['D02.455.426.559.847.638.204', 'D02.886.590.192', 'D04.615.638.204'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480']... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Honey bee colony-level exposure and effects in realistic landscapes: An application of BEEHAVE simulating clothianidin residues in corn pollen. | Discerning potential effects of insecticides on honey bee colonies in field studies conducted under realistic conditions can be challenging because of concurrent interactions with other environmental conditions. Honey bee colony models can control exposures and other environmental factors, as well as assess links among... | ['Animals', 'Bees', 'Environmental Monitoring', 'Guanidines', 'Insecticides', 'Minnesota', 'Models, Theoretical', 'Neonicotinoids', 'Pesticide Residues', 'Plant Nectar', 'Pollen', 'Risk Assessment', 'South Dakota', 'Thiazoles', 'Wisconsin', 'Zea mays'] | 30,575,066 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.078.370'], ['D27.720.031.700.491', 'D27.888.723.491'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['E05.599'], ['D03.383.464'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['D... | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Soil-to-cassava transfer of naturally occurring radionuclides from communities along Ghana's oil and gas rich Tano Basin. | Soil-to-plant transfer factor (TF) is widely used to assess the impact of soil radioactivity on agricultural crops. The root crop cassava (Manihot esculenta) provides 30%-50% of the calories consumed in Sub-Saharan Africa and is widely used in South America. ã-ray analysis was used to measure activity concentrations of... | ['Background Radiation', 'Ghana', 'Manihot', 'Radiation Monitoring', 'Radioactivity', 'Soil', 'Soil Pollutants, Radioactive'] | 29,227,875 | [['G01.750.750.115'], ['Z01.058.290.190.320'], ['B01.650.940.800.575.912.250.859.797.438.535'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['G01.828'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D20.693.756', 'D27.888.284.756.674']] | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Increased neonatal fat mass, not lean body mass, is associated with maternal obesity. | OBJECTIVE: The purpose of this study was to compare body composition measures in neonates of women who were overweight/obese (body mass index, > or = 25 kg/m2) versus women who were lean/average (body mass index, < 25 kg/m2), all of whom had normal glucose tolerance levels.STUDY DESIGN: Seventy-six neonates (34 female ... | ['Adiposity', 'Adult', 'Birth Weight', 'Body Composition', 'Body Mass Index', 'Female', 'Fetal Development', 'Humans', 'Infant, Newborn', 'Male', 'Multivariate Analysis', 'Obesity', 'Pregnancy', 'Regression Analysis'] | 16,875,645 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.12... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Etiologic diagnosis of lower respiratory tract infections. | Decision as to the role of infection in lower respiratory tract disease requires examination by culture of specimens known to be derived from the infra-laryngeal respiratory tract. Methods that involve the upper respiratory tract in collection of specimens entail the hazard of contamination by microbiota resident in th... | ['Humans', 'Respiratory Tract Infections'] | 5,470,140 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748', 'C08.730']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Iron complexation to oxygen rich marine natural products: a computational study. | The natural products kahalalide F, halichondrin B, and discodermolide are relatively large structures that were originally harvested from marine organisms. They are oxygen rich structures that, to varying degrees, should have the ability to bind iron (II or III) by Fe-O and/or Fe-N bonds. In this semi empirical study, ... | ['Alkanes', 'Animals', 'Antineoplastic Agents', 'Biological Products', 'Carbamates', 'Cell Line, Tumor', 'Chemical Phenomena', 'Computational Biology', 'Depsipeptides', 'Ethers, Cyclic', 'Humans', 'Inhibitory Concentration 50', 'Iron', 'Lactones', 'Macrolides', 'Models, Molecular', 'Molecular Conformation', 'Neoplasms'... | 20,161,968 | [['D02.455.326.146'], ['B01.050'], ['D27.505.954.248'], ['D20.215'], ['D02.241.081.251'], ['A11.251.210.190', 'A11.251.860.180'], ['G02'], ['H01.158.273.180', 'L01.313.124'], ['D04.345.566.297', 'D12.644.641.297'], ['D02.355.291', 'D04.345.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The characterization of the mechanical properties of microcrystalline cellulose: a fracture mechanics approach. | The mechanical properties of compressed beam specimens of microcrystalline cellulose (Avicel pH 101) have been assessed in terms of the tensile strength (sigma t), Young's modulus (E) and the following fracture mechanics parameters: the critical stress intensity factor (KIC), the critical strain energy release rate (GI... | ['Cellulose', 'Excipients', 'Hardness', 'Microscopy, Electron', 'Tensile Strength'] | 2,894,442 | [['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D26.650.700.419', 'D27.720.744.770.419'], ['G01.374.647'], ['E01.370.350.515.402', 'E05.595.402'], ['G01.374.850']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Lipid quantification and structure determination of nuclear envelope precursor membranes in the sea urchin. | Nuclear envelope assembly is a fundamental cellular process normally taking place once in every cell cycle in eukaryotes. The timing of fusion of nuclear membrane precursors to form the complete double membrane surrounding the chromosomes is tightly controlled, but much remains unclear concerning its regulation. Small ... | ['Animals', 'Cholesterol', 'Cholesterol Esters', 'Chromatography, High Pressure Liquid', 'Filipin', 'Lipids', 'Magnetic Resonance Spectroscopy', 'Microscopy, Electron', 'Nuclear Envelope', 'Phosphates', 'Phosphatidylinositols', 'Sea Urchins', 'Staining and Labeling', 'Tandem Mass Spectrometry'] | 19,160,663 | [['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['E05.196.181.400.300'], ['D02.455.326.271.665.325', 'D02.540.576.500.996'], ['D10'], ['E05.196.867.519'], ['E01.370.350.515.402', 'E05.595.402'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contractile behaviour in skeletal muscle-tendon unit during small amplitude sine wave perturbations. | The effects of sinusoidal vibrations (0.2 mm) on contractile behaviour of the medial gastrocnemius muscle of the rat (N = 6) were determined over a wide range of frequencies (10-210 Hz). The performance of the contractile element (CE) during maximal tetanic contractions and vibrations was calculated by correcting muscl... | ['Animals', 'Computer Simulation', 'Male', 'Models, Biological', 'Muscle Contraction', 'Muscle, Skeletal', 'Rats', 'Rats, Wistar', 'Tendons', 'Vibration'] | 8,872,271 | [['B01.050'], ['L01.224.160'], ['E05.599.395'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A02.880'], ['G01.374.930']] | ['Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Role of folylpolyglutamate synthetase in the metabolism and cytotoxicity of 5-deazaacyclotetrahydrofolate, an anti-purine drug. | Chinese hamster ovary (CHO) cells expressing human and Escherichia coli folylpolyglutamate synthetase (FPGS) activities were used as models to study factors regulating the cytotoxicity and metabolism of 5-deazaacyclotetrahydrofolate (DATHF), an anti-purine agent that requires conversion to polyglutamate forms to be a p... | ['Animals', 'CHO Cells', 'Cell Division', 'Cell Survival', 'Cricetinae', 'Escherichia coli', 'Glutamates', 'Glycine', 'Humans', 'Hypoxanthine', 'Hypoxanthines', 'Mitochondria', 'Peptide Synthases', 'Pyrimidines', 'Tetrahydrofolates', 'Thymidine', 'Transfection'] | 8,144,562 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['B01.050.150.900.649.313.992.635.075.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.481'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early post implantation contraceptive effects of a purified fraction of neem (Azadirachta indica) seeds, given orally in rats: possible mechanisms involved. | Neem seed and leaf extracts have immunomodulators that induce cellular immune reactions. These aspects of neem were exploited in earlier studies, where the oral administration of the neem seed extracts in rodents and primates could completely abrogate pregnancy at an early post implantation stage. Complete restoration ... | ['Abortifacient Agents', 'Administration, Oral', 'Animals', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Dose-Response Relationship, Drug', 'Embryonic Development', 'Female', 'Lymph Nodes', 'Organ Size', 'Plant Extracts', 'Pregnancy', 'Rats', 'Rats, Wistar', 'Seeds', 'Spleen'] | 10,617,063 | [['D27.505.696.875.131', 'D27.505.954.705.131'], ['E02.319.267.100'], ['B01.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G07.690.773.875', 'G07.690.936.500'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparative study of the efficacy of argon laser trabeculoplasty for exfoliation and primary open-angle glaucoma. | PURPOSE: To investigate the efficacy of argon laser trabeculoplasty (ALT) for the treatment of primary open-angle glaucoma (POAG) and of glaucoma associated with exfoliation syndrome (EXF).METHODS: Review of > 200 charts from patients treated with ALT between 1981 and 1987 identified 66 POAG and 29 EXF eyes that underw... | ['Exfoliation Syndrome', 'Female', 'Follow-Up Studies', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Laser Therapy', 'Male', 'Prognosis', 'Trabeculectomy'] | 8,897,230 | [['C11.941.375.285'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E02.594', 'E04.014.520'], ['E01.789'], ['E04.540.450.700']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vivo biomicroscopy with ultrasound. | We propose the use of inverse scattering theory methods to analyse high frequency ultrasound reflection data to provide high resolution images of living tissue. Conventional ultrasound imaging uses the pulse-echo method which can only resolve structures which are large compared to the wavelength of the ultrasound. Inve... | ['Acoustics', 'Fourier Analysis', 'Humans', 'Image Enhancement', 'Mathematics', 'Models, Structural', 'Models, Theoretical', 'Retina', 'Spectrum Analysis', 'Ultrasonography'] | 3,310,353 | [['H01.671.031'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['H01.548'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['E05.599'], ['A09.371.729'], ['E05.196.867'], ['E01.370.350.850']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
''Minimizing tacrolimus'' strategy and long-term survival after liver transplantation. | AIM: To investigate the effect of the ''minimizing tacrolimus'' strategy on long-term survival of patients after liver transplantation (LT).METHODS: We conducted a retrospective study of 319 patients who received LT between January 2009 and December 2011 at the First Affiliated Hospital of Zhejiang University School of... | ['Adult', 'Calcineurin Inhibitors', 'Chi-Square Distribution', 'China', 'Female', 'Graft Rejection', 'Graft Survival', 'Humans', 'Immunosuppressive Agents', 'Kaplan-Meier Estimate', 'Liver Transplantation', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk Factors', 'Tacrolimus', 'Tim... | 25,170,223 | [['M01.060.116'], ['D27.505.519.389.174'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['Z01.252.474.164'], ['G12.875.545.328'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E05.318.740.998.650', 'N05.715.360.750.795.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The serine protease inhibitor antithrombin III inhibits LPS-mediated NF-kappaB activation by TLR-4. | In Drosophila, the Toll family of proteins mediates the innate immune response. Toll is activated by Spaetzle, which is generated in response to pathogens via a serine protease cascade. We wished to investigate if lipopolysaccharides (LPS) might activate Toll-like receptor (TLR) 4 via a serine protease in humans. The s... | ['Antithrombin III', 'Cell Line', 'Drosophila Proteins', 'Enzyme Activation', 'Hirudins', 'Humans', 'Lipid A', 'Lipopolysaccharides', 'Membrane Glycoproteins', 'Monocytes', 'NF-kappa B', 'Receptors, Cell Surface', 'Serine Endopeptidases', 'Serine Proteinase Inhibitors', 'Signal Transduction', 'Toll-Like Receptor 4', 'T... | 11,728,442 | [['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['A11.251.210'], ['D12.776.093.500.462'], ['G02.111.263', 'G03.328'], ['D12.644.861.060.875', 'D12.776.872.060.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.718.450.500', 'D10.494.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective solid-phase extraction of artificial chemicals from milk samples using multiple-template surface molecularly imprinted polymers. | A novel multiple-template surface molecularly imprinted polymer (MTMIP) was synthesized using ofloxacin and 17â-estradiol as templates and modified monodispersed poly(glycidylmethacrylate-co-ethylene dimethacrylate) (PGMA/EDMA ) beads as the support material. Static adsorption, solid-phase extraction and high-performan... | ['Adsorption', 'Animals', 'Anti-Bacterial Agents', 'Chromatography, High Pressure Liquid', 'Estradiol', 'Estrogens', 'Food Contamination', 'Milk', 'Molecular Imprinting', 'Ofloxacin', 'Quinolones', 'Reproducibility of Results', 'Solid Phase Extraction'] | 25,677,633 | [['G01.030', 'G02.020'], ['B01.050'], ['D27.505.954.122.085'], ['E05.196.181.400.300'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D27.505.696.399.472.277'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mice do not develop conditioned taste aversion because of immunity loss. | OBJECTIVES: This study intends to test the generation of conditioned taste aversion and conditioned immunodepression by daily paired administration of saccharin solution with cyclophosphamide, 15 mg/kg, for 4 days.METHODS: One group of male mice of the outbred CD1 strain drank 0.15% saccharin and received 1 injection o... | ['Animals', 'Avoidance Learning', 'Conditioning, Psychological', 'Immune Tolerance', 'Immunosuppression', 'Immunosuppressive Agents', 'Male', 'Mice', 'Taste', 'Taste Disorders'] | 21,335,984 | [['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.425.179'], ['G12.535.425'], ['E02.095.465.425.450', 'E05.478.610'], ['D27.505.696.477.656'], ['B01.050.150.900.649.313.992.635.505.500'], ['F02.830.816.724', 'G11.561.790.724'], ['C10.597.751.861', 'C23.888.592.763.861']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of the nitric oxide synthase-nitric oxide-cGMP pathway in rat mesenteric endothelial cells. | Most of the available data on the nitric oxide (NO) pathway in the vasculature is derived from studies performed with cells isolated from conduit arteries. We investigated the expression and regulation of components of the NO synthase (NOS)-NO-cGMP pathway in endothelial cells from the mesenteric vascular bed. Basally,... | ['Animals', 'Aorta', 'Bradykinin', 'Cells, Cultured', 'Colchicine', 'Cyclic GMP', 'Cytokines', 'Endothelium, Vascular', 'Male', 'Muscle, Smooth, Vascular', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Nitric Oxide Synthase Type III', 'Nitrites', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Daw... | 11,717,218 | [['B01.050'], ['A07.015.114.056'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['A11.251'], ['D03.132.225'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D12.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beta-cell function during insulin-modified intravenous glucose tolerance test successfully assessed by the C-peptide minimal model. | The insulin-modified intravenous glucose tolerance test (IM-IVGTT) is increasingly used to measure insulin sensitivity. However, the assessment of beta-cell secretion is usually made using rough indices. The aim here is to evaluate the ability of the minimal model of C-peptide secretion and kinetics recently proposed f... | ['C-Peptide', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Islets of Langerhans', 'Kinetics', 'Middle Aged', 'Sensitivity and Specificity'] | 10,484,058 | [['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A03.734.414', 'A06.300.414'], ['G01.374.661', 'G02.111.490'], ['M01.0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Implications for health care policy. A social and demographic profile of hemodialysis patients in the United States. | Before 1973, selection of patients with end-stage renal diseases (ESRD) for treatment was necessary because of inadequate medical and financial resources. Patients were selected based partly on social worth rather than medical suitability. In 1973 ESRD patients became eligible for Medicare benefits, eliminating the fin... | ['Adolescent', 'Adult', 'Aged', 'Cost Control', 'Cost-Benefit Analysis', 'Education', 'Female', 'Health Services Accessibility', 'Humans', 'Income', 'Kidney Failure, Chronic', 'Male', 'Medicare', 'Middle Aged', 'Patient Selection', 'Renal Dialysis', 'Resource Allocation', 'United States'] | 6,779,018 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N03.219.151.160'], ['N03.219.151.125'], ['I02'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.34... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. | When resectable, invasive pancreatic ductal adenocarcinoma (PDAC) is most commonly treated with surgery and radiochemotherapy. Given the intricate local anatomy and locoregional mode of dissemination, achieving clean surgical margins can be a significant challenge. On the basis of observations that cathepsin E (CTSE) i... | ['Animals', 'Biopsy', 'Boron Compounds', 'Carcinoma, Pancreatic Ductal', 'Cathepsin E', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Fluorescent Dyes', 'HIV Protease Inhibitors', 'Humans', 'Inhibitory Concentration 50', 'Mice', 'Pancreatic Neoplasms', 'Ritonavir'] | 23,814,481 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D01.132', 'D02.203'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.62... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Comparative evaluation of the tiled abutment teeth restored with or without fixed bridge on stress distribution by anisotropic finite element method]. | OBJECTIVE: To compare the tilted abutment teeth restored with or without fixed bridge on stress distribution by anisotropic finite element method when the vertical and the oblique loads are simulated.METHODS: Three-dimensional finite element model was constructed by using SCT image reconstruction technique, self-progra... | ['Adult', 'Anisotropy', 'Computer Simulation', 'Dental Abutments', 'Dental Restoration, Permanent', 'Denture, Partial', 'Finite Element Analysis', 'Humans', 'Male', 'Stress, Mechanical', 'Tooth'] | 17,236,595 | [['M01.060.116'], ['G01.590.040', 'G02.050'], ['L01.224.160'], ['E06.780.346.500', 'E07.695.190.175'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['E06.780.346.760.943', 'E07.695.190.200.220'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.835'], ['A14.549.167.860']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
The role of theory in HIV prevention. | There is growing evidence that well designed, targeted, theory-based behaviour change interventions can be effective in reducing the spread of HIV. Although each behaviour is unique, there are only a limited number of theoretical variables that serve as the determinants of any given behaviour. Understanding these varia... | ['Behavior Therapy', 'HIV Infections', 'Humans', 'Male', 'Models, Psychological', 'Risk-Taking', 'Sexual Behavior'] | 10,928,203 | [['F04.754.137'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F01.145.722'], ['F01.145.802']] | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quality assurance: definition and importance. | Quality assurance is an essential part of health care and nursing. While many nurses are familiar with the words "quality assurance," most are not directly involved in the process. Because of increased requirements for licensure and accreditation, and an increased desire for cost-containment, more nurses will become ac... | ['Ambulatory Surgical Procedures', 'Humans', 'Nursing Care', 'Outpatient Clinics, Hospital', 'Quality Assurance, Health Care', 'Surgery, Plastic'] | 2,381,994 | [['E04.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.611', 'N02.421.533'], ['N02.278.035.380', 'N02.278.216.500.968.527', 'N04.452.442.452.422.527'], ['N04.761.700', 'N05.700'], ['H02.403.810.788']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
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