Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Air filled, inflammatory, lung pseudo-cyst: etio-pathogenesis and management. | Lung cysts in children are usually of congenital origin. Necrotising pneumonias, trauma, cystic fibrosis and kerosene poisoning may be the cause of acquired cysts in the lungs during childhood. We describe a child who presented with pneumothorax and was later discovered to have a cyst in his right lung. The cyst was re... | ['Child', 'Cysts', 'Humans', 'Lung Diseases', 'Male', 'Pneumonectomy', 'Pneumothorax', 'Tomography, X-Ray Computed'] | 19,347,677 | [['M01.060.406'], ['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['E04.620', 'E04.928.600.600'], ['C08.528.778'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Design of a knee rotatory kinaesthetic device. | The anterior cruciate ligament (ACL) constrains rotatory motion at the knee and is commonly injured during rotational movements in athletic activity. This densely innervated ligament is assumed to play a role in knee proprioception, however, no study has measured proprioception in a manner relevant to either the kinema... | ['Adult', 'Anterior Cruciate Ligament', 'Arthrometry, Articular', 'Biomedical Enhancement', 'Equipment Design', 'Exercise Therapy', 'Humans', 'Kinetics', 'Knee', 'Male', 'Proprioception', 'Reproducibility of Results', 'Rotation', 'Task Performance and Analysis'] | 17,123,859 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E01.370.600.700.500', 'G11.427.760.500'], ['E05.104', 'J01.897.120.050.250'], ['E05.320'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490']... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Origin and genetic diversity of Western European populations of the potato cyst nematode (Globodera pallida) inferred from mitochondrial sequences and microsatellite loci. | Native to South America, the potato cyst nematode Globodera pallida is one of the principal pests of Andean potato crops and is also an important global pest following its introduction to Europe, Africa, North America, Asia and Oceania. Building on earlier work showing a clear south to north phylogeographic pattern in ... | ['Alleles', 'Animals', 'Breeding', 'Cytochromes b', 'DNA, Mitochondrial', 'Europe', 'Genetic Variation', 'Haplotypes', 'Microsatellite Repeats', 'Nematoda', 'Peru', 'Phylogeny', 'Plant Diseases', 'Sequence Analysis, DNA', 'Solanum tuberosum'] | 18,410,291 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.820.150', 'G05.090'], ['D08.244.187.249', 'D12.776.422.220.187.249'], ['D13.444.308.283.225'], ['Z01.542'], ['G05.365'], ['G05.380.360'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['B01.050.500.500.294'], ['Z01.107.757.702'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Determination of total iodine in biological material by alkaline ashing and column-switching ion-pair liquid chromatography. | A method for the determination of total iodine in biological material has been developed. The method combines alkaline ashing with a selective and sensitive column-switching ion-pair HPLC technique. The ashing procedure which converts the organically bound iodine to iodide is miniaturised and requires only about 100 mg... | ['Animals', 'Bone and Bones', 'Chromatography, High Pressure Liquid', 'Hydroxides', 'Iodine', 'Liver', 'Lung', 'Potassium Compounds', 'Rats', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Sodium Hydroxide', 'Spectrophotometry, Ultraviolet', 'Tissue Distribution'] | 9,187,383 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['E05.196.181.400.300'], ['D01.045.250', 'D01.248.497.158.459'], ['D01.268.380.400'], ['A03.620'], ['A04.411'], ['D01.745'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
BRCA2 mutations in primary breast and ovarian cancers. | The second hereditary breast cancer gene, BRCA2, was recently isolated. Germline mutations of this gene predispose carriers to breast cancer, and, to a lesser extent, ovarian cancer. Loss of heterozygosity (LOH) at the BRCA2 locus has been observed in 30-40% of sporadic breast and ovarian tumours, implying that BRCA2 m... | ['Aged', 'BRCA2 Protein', 'Base Sequence', 'Breast Neoplasms', 'DNA Primers', 'Female', 'Genetic Markers', 'Heterozygote', 'Humans', 'Lymphocytes', 'Middle Aged', 'Molecular Sequence Data', 'Mutation', 'Neoplasm Proteins', 'Ovarian Neoplasms', 'Retinoblastoma Protein', 'Sequence Deletion', 'Transcription Factors'] | 8,640,235 | [['M01.060.116.100'], ['D12.776.313.249', 'D12.776.624.776.101', 'D12.776.660.105'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.180', 'C17.800.090.500'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D23.101.387', 'G05.695.450'], ['G05.380.383'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Comparison of Affirm VPIII and Papanicolaou tests in the detection of infectious vaginitis. | To compare the Affirm VPIII molecular test (Becton Dickinson, Burlington, NC) with morphologic identification used in routine Papanicolaou (Pap) test screening in the detection and identification of Candida species, Trichomonas vaginalis, and Gardnerella vaginalis, we identified 431 cases with a concomitant Pap test an... | ['Adolescent', 'Adult', 'Aged', 'Bacteriological Techniques', 'Candida', 'Female', 'Gardnerella vaginalis', 'Humans', 'Middle Aged', 'Papanicolaou Test', 'Predictive Value of Tests', 'Reagent Kits, Diagnostic', 'Trichomonas vaginalis', 'Vaginal Smears', 'Vaginitis', 'Young Adult'] | 21,350,100 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B03.510.024.400.800'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.225.500.384.100.422', 'E01.370.225.998.054.422', 'E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serendipitous Discovery of Leucine and Methionine Depletion Agents during the Search for Polyamine Transport Inhibitors. | Targeting polyamine metabolism is a proven anticancer strategy. Cancers often escape the polyamine biosynthesis inhibitors by increased polyamine import. Therefore, there is much interest in identifying polyamine transport inhibitors (PTIs) to be used in combination therapies. In a search for new PTIs, we serendipitous... | ['Animals', 'Benzoxazoles', 'Biological Transport', 'CHO Cells', 'Cricetulus', 'Drug Discovery', 'Humans', 'Large Neutral Amino Acid-Transporter 1', 'Leucine', 'Methionine', 'Polyamines', 'Putrescine', 'Small Molecule Libraries', 'Spermidine', 'Spermine', 'Tyrosine'] | 32,069,402 | [['B01.050'], ['D03.633.100.221'], ['G03.143'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.200.500.500.500.300.500', 'D12.776.157.530.937.313.500.625.500', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrasubject multimodal groupwise registration with the conditional template entropy. | Image registration is an important task in medical image analysis. Whereas most methods are designed for the registration of two images (pairwise registration), there is an increasing interest in simultaneously aligning more than two images using groupwise registration. Multimodal registration in a groupwise setting re... | ['Algorithms', 'Brain Diseases', 'Carotid Arteries', 'Entropy', 'Humans', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Multimodal Imaging', 'Pattern Recognition, Automated', 'Principal Component Analysis', 'Radiotherapy Planning, Computer-Assisted', 'Thorax', '... | 29,502,030 | [['G17.035', 'L01.224.050'], ['C10.228.140'], ['A07.015.114.186'], ['G01.906.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['E01.370.350.567'], ['L01.399.750'], ['E05.318.740.562... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Optimized production and characterization of a detergent-stable protease from Lysinibacillus fusiformis C250R. | In this study, we aimed to optimize the cultural and nutritional conditions for protease production by Lysinibacillus fusiformis strain C250R in submerged fermentation process using statistical methodology. The most significant factors (gruel, wheat bran, yeast extract, and FeSO4) were identified by Plackett-Burman des... | ['Amino Acid Sequence', 'Bacillaceae', 'Biotechnology', 'Carbon', 'Cotton Fiber', 'Detergents', 'Enzyme Stability', 'Hydrogen-Ion Concentration', 'Metals', 'Molecular Weight', 'Nitrogen', 'Peptide Hydrolases', 'Polymers', 'Protease Inhibitors', 'Salts'] | 28,315,440 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158', 'B03.353.500.100', 'B03.510.100.100', 'B03.510.415.400.158', 'B03.510.460.410.158'], ['H01.158.550', 'J01.897.120'], ['D01.268.150'], ['J01.637.836.299'], ['D27.720.877.265', 'J01.516.381'], ['E05.916.360', 'G02.111.700.500'], ['G02.300'], ['D01.552']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Opinions and wearing habits among patients new to removable partial dentures. An interview study. | Thirty-five patients treated at the Department of Prosthetic Dentistry, University of Ume?, who had received removable partial dentures (RPD) during the period July 1st 1981 to December 31st 1982, were interviewed regarding the use and experiences of their dentures. None of the patients had previously used an RPD. The ... | ['Adult', 'Aged', 'Attitude', 'Chromium Alloys', 'Consumer Behavior', 'Denture Design', 'Denture, Partial, Removable', 'Female', 'Humans', 'Interviews as Topic', 'Male', 'Mandible', 'Mastication', 'Maxilla', 'Middle Aged', 'Speech'] | 2,667,182 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100'], ['D01.220.175', 'D01.552.033.182', 'D25.058.224', 'D25.339.208.224', 'J01.637.051.058.224', 'J01.637.051.339.208.224'], ['F01.145.236'], ['E06.780.346.760.300', 'E06.912.250'], ['E06.780.346.760.943.413', 'E07.695.190.200.220.230'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Movement-related cortical evoked potentials using four-limb imagery. | We compared the electroencephalographic changes during actual and imaginary movements with four limbs and classified optimally the responses during four-limb imagery. Evoked potentials in imagery exhibited lower and delayed peaks compared to actual-movement responses, but activations in the primary and the supplementar... | ['Algorithms', 'Brain', 'Brain Mapping', 'Electroencephalography', 'Evoked Potentials, Motor', 'Foot', 'Frontal Lobe', 'Hand', 'Humans', 'Imagination', 'Motor Cortex', 'Movement', 'Parietal Lobe', 'Prefrontal Cortex', 'Psychomotor Performance'] | 19,283,591 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['A01.378.610.250'], ['A08.186.211.200.885.287.500.270'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nineteen year results of THA using modular 9 mm S-ROM femoral component in patients with small femoral canals. | A retrospective analysis was undertaken of 30 consecutive THA performed in 25 patients with hypoplastic proximal femurs, who had received a 9-mm uncemented modular S-ROM stem. The mean patient age was 42 years (17-69 years), mean height was 152.5 cm (130-170.5 cm), mean weight was 63 kg (39-90 kg), and mean follow-up p... | ['Adolescent', 'Adult', 'Aged', 'Arthroplasty, Replacement, Hip', 'Female', 'Femur', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Joint Diseases', 'Male', 'Middle Aged', 'Radiography', 'Young Adult'] | 23,618,752 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['A02.835.232.043.150'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['M01.060.116.630'], ['E01.370.350.700'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incidental non-inguinals hernias in totally extra-peritoneal hernia repair. | INTRODUCTION: Totally extra-peritoneal (TEP) inguinal hernia repair allows identification and repair of incidental non-inguinal groin hernias. We assessed the prevalence of incidental hernias during TEP inguinal hernia repair and identified the risk factors for incidental hernias.MATERIALS AND METHODS: Consecutive pati... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Female', 'Hernia, Femoral', 'Hernia, Inguinal', 'Hernia, Obturator', 'Humans', 'Incidental Findings', 'Male', 'Middle Aged', 'Recurrence', 'Risk Factors', 'Sex Factors', 'Young Adult'] | 25,723,688 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.300.707.374.750'], ['C23.300.707.374.875'], ['C23.300.707.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular modeling study on the drug resistance mechanism of NS5B polymerase to TMC647055. | NS5B polymerase plays an important role in viral replication machinery. TMC647055 (TMC) is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase. However, mutations that result in drug resistance to TMC have been reported. In this study, we used molecular dynamics (MD) simulations, binding free energy ... | ['Antiviral Agents', 'Dose-Response Relationship, Drug', 'Drug Resistance, Viral', 'Enzyme Inhibitors', 'Heterocyclic Compounds, 4 or More Rings', 'Models, Molecular', 'Mutation', 'Structure-Activity Relationship', 'Sulfonamides', 'Thermodynamics', 'Viral Nonstructural Proteins'] | 26,836,778 | [['D27.505.954.122.388'], ['G07.690.773.875', 'G07.690.936.500'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['D27.505.519.389'], ['D03.633.400'], ['E05.599.595'], ['G05.365.590'], ['G02.111.830', 'G07.690.773.997'], ['D02.065.884', 'D02.886.590.700'], ['G01.906'], ['D12.776.964.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of different quantitative PCR procedures in the analysis of the 4977-bp deletion in human mitochondrial DNA. | Four quantitative PCR procedures were compared to analysing the level of the 4977 bp deletion in human mitochondrial DNA. A single preparation of total cellular DNA from the heart of a 69-year-old female subject was used for all four methods. We estimated the deletion to represent 0.005% of total mtDNA molecules using ... | ['Aged', 'Autoradiography', 'DNA Primers', 'DNA, Mitochondrial', 'Deoxycytosine Nucleotides', 'Female', 'Humans', 'Mitochondria, Heart', 'Phosphorus Radioisotopes', 'Plasmids', 'Polymerase Chain Reaction', 'Reference Standards', 'Reproducibility of Results', 'Sequence Deletion'] | 8,670,302 | [['M01.060.116.100'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.283.225'], ['D03.383.742.686.246.425', 'D13.695.201.150', 'D13.695.740.246.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.564.627.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Muesothelial cyst of the spermatic cord as a cause of acquired cryptorchidism. | Mesothelial cysts of the spermatic cord (MCSC) are a rare entity. A 2-year-old cryptorchid boy with an inguinal mass was found to have a MCSC which was confused with undescended testis. The testis was readily placed into the hemiscrotum after excision of the cyst. MCSC may present as undescended testis and may be an un... | ['Biopsy, Needle', 'Child, Preschool', 'Cryptorchidism', 'Cysts', 'Epithelium', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Inguinal Canal', 'Male', 'Rare Diseases', 'Risk Assessment', 'Spermatic Cord', 'Treatment Outcome'] | 19,085,038 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['M01.060.406.448'], ['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['C04.182', 'C23.300.306'], ['A10.272'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Resistance to 5-fluorouracil and 5-fluoro-2'-deoxyuridine mechanisms and clinical implications. | Preliminary to studies on biopsy specimens from colorectal carcinomas, we have investigated the mechanisms of resistance to 5-fluorouracil (FUra) and 5-fluoro-2'-deoxyuridine (FdUrd) on a human colon carcinoma cell line, HCT-8 in vitro. After obtaining a high level of resistance, extracts were made from sensitive and r... | ['Colonic Neoplasms', 'Dose-Response Relationship, Drug', 'Drug Resistance', 'Floxuridine', 'Fluorouracil', 'Humans', 'Time Factors', 'Tumor Cells, Cultured'] | 2,142,213 | [['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984'], ['D03.383.742.680.852.300.350', 'D13.570.230.430.432', 'D13.570.685.852.300.350'], ['D03.383.742.698.875.404'], ['B01... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor. | Cellular cholesterol levels reflect a balance between uptake, efflux, and endogenous synthesis. Here we show that the sterol-responsive nuclear liver X receptor (LXR) helps maintain cholesterol homeostasis, not only through promotion of cholesterol efflux but also through suppression of low-density lipoprotein (LDL) up... | ['Animals', 'Cell Line, Tumor', 'Cholesterol', 'DNA-Binding Proteins', 'Homeostasis', 'Humans', 'Ligands', 'Lipoproteins, LDL', 'Liver', 'Liver X Receptors', 'Mice', 'Mice, Inbred C57BL', 'Orphan Nuclear Receptors', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Receptors, Cytoplasmic and Nuclear', 'Receptors, LDL', '... | 19,520,913 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D12.776.260'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['D10.532.515', 'D12.776.521.550'], ['A03.620'], ['D12.776.260.531', 'D12.776.826.194'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of heparan sulfate proteoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells. | Addition of apolipoprotein (apo) E to rabbit beta-very low density lipoproteins (beta-VLDL) has been shown to result in a marked enhancement of their binding and uptake by various cell types. Apolipoprotein E binds to lipoprotein receptors and proteoglycans. To distinguish between apoE binding to these sites, cells wer... | ['Animals', 'Apolipoproteins E', 'Biological Transport', 'CHO Cells', 'Carcinoma, Hepatocellular', 'Cell Membrane', 'Cells, Cultured', 'Cholesterol', 'Cholesterol Esters', 'Cricetinae', 'Diet, Atherogenic', 'Fibroblasts', 'Heparan Sulfate Proteoglycans', 'Heparin Lyase', 'Heparitin Sulfate', 'Humans', 'Hyperlipoprotein... | 7,683,668 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['G03.143'], ['A11.251.210.200', 'A11.436.155'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.284.149'], ['A11.251'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.20... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reconstruction of major arteries of extremities after war injuries. | This paper reports on the experience regarding the reconstruction of arterial injuries gained at the Department of Surgery, Osijek General Hospital during the first year of war against Croatia. In the period between May 1991 and May 1992, 57 wounded with 60 injuries of the major arteries of the extremities were admitte... | ['Adult', 'Aged', 'Arm', 'Arteries', 'Child, Preschool', 'Croatia', 'Female', 'Humans', 'Leg', 'Male', 'Transplantation, Homologous', 'Treatment Outcome', 'Vascular Surgical Procedures', 'Veins', 'Warfare', 'Wounds and Injuries'] | 8,482,702 | [['M01.060.116'], ['M01.060.116.100'], ['A01.378.800.075'], ['A07.015.114'], ['M01.060.406.448'], ['Z01.542.248.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['E04.936.864'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E04.100.814'], ['A07.015.908'], ['I01.880.735... | ['Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Modeling the Effect of Physical Activity on Obesity in China: Evidence from the Longitudinal China Health and Nutrition Study 1989-2011. | Although physical activity has been widely recognized as an important influential factor in determining the risk of obesity, the results in the existing literature empirically examining such issue are mixed. Especially for China, relevant studies are rarely found. One aim of this study is to test the direction of effec... | ['Adolescent', 'Adult', 'Body Weight', 'Child', 'China', 'Cross-Sectional Studies', 'Exercise', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Theoretical', 'Obesity'] | 28,749,417 | [['M01.060.057'], ['M01.060.116'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.9... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Self-reported Balance Disturbance and Performance-Based Balance Impairment After Concussion in the General Population. | OBJECTIVE: To characterize the prevalence of, and relationship between, self-reported balance disturbance and performance-based balance impairment in the general population with concussion.SETTING: Rehabilitation hospital outpatient concussion clinic.PARTICIPANTS: One hundred six individuals with concussion (49 males, ... | ['Adult', 'Brain Concussion', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Postural Balance', 'Prevalence', 'Reproducibility of Results', 'Self Report', 'Sensation Disorders', 'Young Adult'] | 30,169,435 | [['M01.060.116'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.752', 'G... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sensorimotor skills and language comprehension in autistic children. | The objectives of this study were to examine the level of sensorimotor concepts of young autistic children and to relate these concepts to language comprehension. A sample of 16 autistic children with a mean mental age of 24.8 months was administered a standardized scale of sensorimotor intelligence and of receptive la... | ['Age Factors', 'Autistic Disorder', 'Child', 'Child, Preschool', 'Concept Formation', 'Female', 'Humans', 'Infant', 'Intelligence', 'Language Development', 'Language Tests', 'Male', 'Motor Skills'] | 7,276,397 | [['N05.715.350.075', 'N06.850.490.250'], ['F03.625.164.113.500'], ['M01.060.406'], ['M01.060.406.448'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.752.543'], ['F01.525.200.310'], ['F04.711.513.240'], ['F02.808.260']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death. | The tumour suppressor p53 is an important mediator of cell cycle arrest and apoptosis in response to DNA damage, acting mainly by transcriptional regulation of specific target genes. The exact details how p53 modulates this decision on a molecular basis is still incompletely understood. One mechanism of regulation is a... | ['Acetylation', 'Animals', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'DNA Damage', 'DNA Repair', 'Gene Expression Regulation', 'HCT116 Cells', 'Histone Acetyltransferases', 'Humans', 'Lysine Acetyltransferase 5', 'Mice', 'Neoplasm Proteins', 'RNA Interference', 'RNA, Sm... | 26,062,895 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.200'], ['G02.111.222', 'G05.219'], ['G05.308'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['D08.811.913.050.134.415.500']... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modelling tooth emergence data based on multivariate interval-censored data. | Studies on emergence of (permanent) teeth are published regularly in the dental literature. Besides descriptive statistics (mean or median values) on emergence times, comparisons between boys and girls are of interest. Gender comparisons are intersubject analyses, but also intrasubject questions, like 'Is there a left-... | ['Age Factors', 'Belgium', 'Child', 'Female', 'Humans', 'Male', 'Models, Biological', 'Models, Statistical', 'Multivariate Analysis', 'Sex Factors', 'Tooth Eruption'] | 12,483,766 | [['N05.715.350.075', 'N06.850.490.250'], ['Z01.542.115'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['N05.715.350.675'... | ['Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pharmacological properties of CGS 35066, a potent and selective endothelin-converting enzyme inhibitor, in conscious rats. | The purpose of this study was to examine the pharmacologic properties of CGS 35066, a novel aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibited the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 +/- 0.9 nM and 2.3 +/- 0.03 m... | ['Animals', 'Aspartic Acid Endopeptidases', 'Atrial Natriuretic Factor', 'Benzofurans', 'Blood Pressure', 'Endothelin-Converting Enzymes', 'Humans', 'Male', 'Metalloendopeptidases', 'Neprilysin', 'Organophosphonates', 'Protease Inhibitors', 'Rats', 'Rats, Sprague-Dawley'] | 11,078,331 | [['B01.050'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['D03.633.100.127'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D08.811.277.656.074.500.270', 'D08.811.277.656.300.048.270', 'D08.811.277.656.300.480.229', 'D08.811.277.656.675.374.229'], ['B01.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554. | N-(2-Hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) is a fluorinated 2-nitroimidazole which has been rationally designed as a non-invasive probe for tumor hypoxia. The key selection criteria for this molecule were low central nervous system penetration and toxicity, high metabolic stability... | ['Animals', 'Biological Availability', 'Brain', 'Cell Hypoxia', 'Female', 'Liver', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Inbred BALB C', 'Molecular Probes', 'Neoplasm Transplantation', 'Nitroimidazoles', 'Tissue Distribution'] | 8,663,910 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['A08.186.211'], ['G03.197.300', 'G04.270.300'], ['A03.620'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['D27.505.259.750', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using EHRs and Machine Learning for Heart Failure Survival Analysis. | "Heart failure (HF) is a frequent health problem with high morbidity and mortality, increasing prevalence and escalating healthcare costs" [1]. By calculating a HF survival risk score based on patient-specific characteristics from Electronic Health Records (EHRs), we can identify high-risk patients and apply individual... | ['Aged', 'Data Mining', 'Death, Sudden, Cardiac', 'Electronic Health Records', 'Female', 'Heart Failure', 'Humans', 'Machine Learning', 'Male', 'Minnesota', 'Natural Language Processing', 'Pattern Recognition, Automated', 'Population Surveillance', 'Prevalence', 'Risk Factors', 'Survival Analysis'] | 26,262,006 | [['M01.060.116.100'], ['L01.313.500.750.280.199', 'L01.470.625'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.... | ['Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial. | Cardiovascular diseases are nowadays preferential targets of preventive medicine through a straightforward therapy on lipid profile. However, statins, the first-line lipid-lowering drug therapy, specifically act on low-density lipoprotein cholesterol (LDL-C), having a modest effect on plasma high-density lipoprotein ch... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Cholesterol', 'Dietary Supplements', 'Female', 'Humans', 'Hypolipidemic Agents', 'Male', 'Malus', 'Middle Aged', 'Plant Extracts', 'Young Adult'] | 28,296,588 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G07.203.300.456', 'J02.500.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071', 'D27.505.954.557.500'], ['B01.650.940.800.575.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Tea contains potent inhibitors of tyrosine phosphatase PTP1B. | Tea is widely consumed all over the world. Studies have demonstrated the role of tea in prevention and treatment of various chronic diseases including diabetes and obesity, but the underlying mechanism is unclear. PTP1B is a widely expressed tyrosine phosphatase which has been defined as a target for therapeutic drug d... | ['Animals', 'Camellia sinensis', 'Catechin', 'Chromatography, Reverse-Phase', 'Humans', 'Mice', 'Monophenol Monooxygenase', 'NIH 3T3 Cells', 'Oxidation-Reduction', 'Phosphorylation', 'Protein Kinase Inhibitors', 'Protein Tyrosine Phosphatase, Non-Receptor Type 1', 'Tea', 'Tyrosine'] | 21,371,422 | [['B01.050'], ['B01.650.940.800.575.912.250.341.998.500.500'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['E05.196.181.400.495'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.682.690.70... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Nineteen years survival after occlusion of the left main coronary artery by virtue of an anomalous septal branch. | This case presents a patient who survived 19 years with an occluded left main coronary artery as a result of collateral flow to the anterior wall from an anomalous septal branch arising from the right coronary artery. The case illustrates that minor variations in coronary anatomy may have important effects on the progn... | ['Adult', 'Collateral Circulation', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Circulation', 'Coronary Vessel Anomalies', 'Exercise Test', 'Follow-Up Studies', 'Humans', 'Male', 'Myocardial Infarction', 'Myocardial Ischemia', 'Survival Rate'] | 8,221,848 | [['M01.060.116'], ['G09.330.100.248'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['G09.330.100.324'], ['C14.240.400.210', 'C14.280.400.210', 'C16.131.240.400.210'], ['E01.370.370.380.250', 'E01... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. | The S. cerevisiae Cdc13 is a multifunctional protein with key roles in regulation of telomerase, telomere end protection, and conventional telomere replication, all of which are cell cycle-regulated processes. Given that phosphorylation is a key mechanism for regulating protein function, we identified sites of phosphor... | ['Cell Cycle', 'DNA Replication', 'Mutation', 'Phosphorylation', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Tandem Mass Spectrometry', 'Telomerase', 'Telomere', 'Telomere Homeostasis', 'Telomere-Binding Proteins'] | 23,181,431 | [['G04.144'], ['G02.111.225', 'G05.226'], ['G05.365.590'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['E05.196.566.880'], ['D08.811.913.696.445.308.300.750.750', 'D12.776.157.687.613', 'D12.776.157.725.500.921', 'D12.776.660.720.613', 'D12.776.66... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Repeated range expansions and inter-/postglacial recolonization routes of Sargentodoxa cuneata (Oliv.) Rehd. et Wils. (Lardizabalaceae) in subtropical China revealed by chloroplast phylogeography. | Most plant phylogeographic studies in subtropical China have stressed the importance of multiple refugia and limited admixture among refugia. Little attention has been paid to range expansion and recolonization routes in this region. In this study, we implemented a phylogeographic survey on Sargentodoxa cuneata, a wide... | ['Bayes Theorem', 'Biological Evolution', 'China', 'DNA, Chloroplast', 'DNA, Plant', 'DNA, Ribosomal Spacer', 'Genetic Variation', 'Haplotypes', 'Magnoliopsida', 'Phylogeny', 'Phylogeography', 'Sequence Analysis, DNA'] | 25,732,070 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.045', 'G16.075'], ['Z01.252.474.164'], ['D13.444.308.283.170', 'D13.444.308.435.275'], ['D13.444.308.435'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['G05.365'], ['G05.380.360'], ['B01.650.940.800.575.912.250'], ['G05.697', 'G1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Allergic fungal rhinosinusitis: an attempt to resolve the diagnostic dilemma. | OBJECTIVE: To resolve the diagnostic dilemma of allergic fungal rhinosinusitis (AFRS), an increasingly recognized type of chronic rhinosinusitis (CRS). In spite of extensive studies, controversy exists regarding the etiologic characteristics, pathogenesis, and diagnosis of this entity.DESIGN: Prospective, comparative s... | ['Adult', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mycoses', 'Paranasal Sinuses', 'Prospective Studies', 'Rhinitis, Allergic, Perennial', 'Sinusitis', 'Skin Tests', 'Tomography, X-Ray Computed'] | 16,490,875 | [['M01.060.116'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.703'], ['A04.531.621'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C08.460.799.315.500', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fatty acid synthesis and metabolism of phospholipid acyl groups in strain L mouse fibroblasts. | Strain L mouse fibroblasts grown in medium supplemented with 2.5% delipidized horse serum were found capable of desaturating oleic and linoleic acid to dienoic and trienoic acid(s), respectively. Although 40-60% of de novo fatty acid synthesis from [2-3H]acetate was inhibited by the administration of exogenous oleic or... | ['Fatty Acids', 'Kinetics', 'L Cells', 'Linoleic Acids', 'Lipids', 'Oleic Acids', 'Phospholipids', 'Sterols'] | 588,578 | [['D10.251'], ['G01.374.661', 'G02.111.490'], ['A11.251.210.505', 'A11.329.228.505'], ['D10.251.355.310.515', 'D10.251.355.343.500'], ['D10'], ['D10.251.355.325.600'], ['D10.570.755'], ['D04.210.500.247.808', 'D10.570.938']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urodynamics after TURP and HoLEP in urodynamically obstructed patients: are there any differences at 1 year of follow-up? | OBJECTIVES: To compare urodynamic findings after holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia-related bladder outlet obstruction.METHODS: From January to October 2002, 100 consecutive patients with benign prostatic... | ['Aged', 'Follow-Up Studies', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Prostatic Hyperplasia', 'Time Factors', 'Transurethral Resection of Prostate', 'Urinary Bladder Neck Obstruction', 'Urodynamics'] | 16,750,253 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['C12.294.565.500'], ['G01.910.857'], ['E04.950.774.860.625.750'], ['C12.777.767.700.962', 'C12.777.829.760',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Shame and implicit self-concept in women with borderline personality disorder. | OBJECTIVE: Shame is considered to be a central emotion in borderline personality disorder and to be related to self-injurious behavior, chronic suicidality, and anger-hostility. However, its level and impact on people with borderline personality disorder are largely unknown. The authors examined levels of self-reported... | ['Adolescent', 'Adult', 'Anger', 'Anxiety', 'Borderline Personality Disorder', 'Diagnosis, Differential', 'Emotions', 'Female', 'Guilt', 'Hostility', 'Humans', 'Middle Aged', 'Personality Inventory', 'Phobic Disorders', 'Psychotherapy', 'Quality of Life', 'Self Concept', 'Sex Factors', 'Shame', 'Surveys and Questionnai... | 17,329,476 | [['M01.060.057'], ['M01.060.116'], ['F01.470.093'], ['F01.470.132'], ['F03.675.100'], ['E01.171'], ['F01.470'], ['F01.470.483'], ['F01.470.596'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.647.513'], ['F03.080.725'], ['F04.754'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.8... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Impact of Candida albicans hyphal wall protein 1 (HWP1) genotype on biofilm production and fungal susceptibility to microglial cells. | The hyphal wall protein 1 (HWP1) gene of Candida albicans encodes for a fungal cell wall protein, required for hyphal development and yeast adhesion to epithelial cells; yet, its role in pathogenesis remains largely unknown. In the present study, we analyzed two C. albicans laboratory strains, the DAY286 (HWP1/HWP1) an... | ['Biofilms', 'Candida albicans', 'Fungal Proteins', 'Gene Expression Profiling', 'Genotype', 'Hyphae', 'Membrane Glycoproteins', 'Microbial Viability', 'Microglia', 'Microscopy, Electron, Transmission', 'Nitric Oxide', 'Tumor Necrosis Factor-alpha'] | 24,685,698 | [['A20.593', 'G06.120'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D12.776.354'], ['E05.393.332'], ['G05.380'], ['A19.687.400'], ['D12.776.395.550', 'D12.776.543.550'], ['G06.580'], ['A08.637.400', 'A11.650.400'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D01.339.387', 'D01.62... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Laboratory diagnosis of infected pancreonecrosis]. | The results of treatment and examination were analyzed in 175 patients admitted to a clinic for sterile pancreonecrosis (PN). The significance of routinely available (clinical, biochemical, and microbiological) laboratory tests in the diagnosis of purulent complications was analyzed in patients with varying severity of... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bacterial Infections', 'Bacteriological Techniques', 'Clinical Laboratory Techniques', 'Humans', 'Middle Aged', 'Pancreatitis, Acute Necrotizing', 'Young Adult'] | 21,319,389 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.150.252'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689.750.650'], ['M01.060.116.815']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of T-helper type 2 cell and airway eosinophilia by transmucosal coadministration of antigen and oligodeoxynucleotides containing CpG motifs. | The characteristic features of bronchial asthma, including airway eosinophilia and elevated immunoglobulin (Ig)E levels, are known to be orchestrated by T-helper (Th) 2 cells. Oligodeoxynucleotides containing CpG motifs (CpG) have recently been highlighted as an immunomodulator that biases toward a Th1-dominant phenoty... | ['Animals', 'Asthma', 'Base Sequence', 'CpG Islands', 'DNA Primers', 'Eosinophilia', 'Mice', 'Mice, Inbred BALB C', 'Mucous Membrane', 'Oligodeoxyribonucleotides', 'Ovalbumin', 'Th2 Cells', 'Trachea'] | 10,657,938 | [['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C15.378.553.231'], ['B01.050.150.900... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The major transition state in folding need not involve the immobilization of side chains. | During protein folding in which few, if any, definable kinetic intermediates are observable, the nature of the transition state is central to understanding the course of the reaction. Current experimental data does not distinguish the relative contributions of side chain immobilization and dehydration phenomena to the ... | ['Animals', 'Chickens', 'Circular Dichroism', 'Cystatins', 'Cystine', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Oxidation-Reduction', 'Protein Conformation', 'Protein Folding', 'Recombinant Fusion Proteins', 'Thermodynamics'] | 10,823,937 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.867.151'], ['D12.776.215'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['E05.196.867.519'], ['E05.599.595'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Berberine diminishes the side population and ABCG2 transporter expression in MCF-7 breast cancer cells. | The plant alkaloid berberine has many biological activities including the ability to induce cell cycle arrest and apoptosis, making it a potentially useful agent for targeting cancer cells. We have analyzed the effects of berberine on MCF-7 breast cancer cells. Berberine was added to MCF-7 cells in culture, and prolife... | ['ATP Binding Cassette Transporter, Subfamily G, Member 2', 'ATP-Binding Cassette Transporters', 'Antineoplastic Agents', 'Benzimidazoles', 'Berberine', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cell Proliferation', 'Coloring Agents', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Neoplasm Proteins', 'St... | 18,951,337 | [['D12.776.157.530.100.228.500', 'D12.776.395.550.020.457.500', 'D12.776.543.550.192.457.500', 'D12.776.543.585.100.228.500'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954.248'], ['D03.633.100.103'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['C04.588... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal Employment Status and Minimum Meal Frequency in Children 6-23 Months in Tanzania. | As women in developing world settings gain access to formal work sectors, it is important to understand how such changes might influence child nutrition. The purpose of this paper is to examine the relationship between maternal employment status and minimum meal frequency (MMF) among children in Tanzania. Interviews we... | ['Adult', 'Employment', 'Female', 'Health Surveys', 'Humans', 'Infant', 'Male', 'Meals', 'Mothers', 'Nutrition Surveys', 'Socioeconomic Factors', 'Tanzania', 'Young Adult'] | 30,934,891 | [['M01.060.116'], ['N01.824.245'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.300.590', 'J02.500.590'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['E05.318.308.980.485', 'N05.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Staged laryngotracheoplasty in adult laryngotracheal stenosis: predictors of long-term decannulation. | IMPORTANCE: This study reviews a single center's experience of performing staged laryngotracheoplasty (LTP) for the treatment of laryngotracheal stenosis with the ultimate goal of attaining long-term airway patency without restenosis.OBJECTIVE: To identify staged LTP as an efficacious surgical treatment option for lary... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Follow-Up Studies', 'Humans', 'Laryngostenosis', 'Larynx', 'Male', 'Middle Aged', 'Mouth Mucosa', 'Multivariate Analysis', 'Otorhinolaryngologic Surgical Procedures', 'Retrospective Studies', 'Severity of Illness Index', 'Stents', 'Trachea', 'Tracheal Sten... | 25,541,839 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360.591', 'C09.400.591', 'C16.131.740.658'], ['A04.329'], ['M01.060.116.630'], ['A10.615.550.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Medicaid family planning expansions and related preventive care. | I examined the impact of state expansions in eligibility for Medicaid family planning services on the utilization of Papanicolaou (Pap) tests, clinical breast examinations, HIV testing, and routine doctor check-ups among women aged 21 to 44 years using the Behavioral Risk Factor Surveillance System (1993-2009). Using a... | ['AIDS Serodiagnosis', 'Adult', 'Behavioral Risk Factor Surveillance System', 'Breast Diseases', 'Family Planning Services', 'Female', 'Humans', 'Medicaid', 'Papanicolaou Test', 'Preventive Medicine', 'United States', 'Vaginal Smears', 'Young Adult'] | 23,865,669 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.116'], ['E05.318.308.980.438.149', 'N05.715.360.300.800.438.149', 'N06.850.520.308.980.438.149'], ['C17.800.090'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Operative Outcomes of Multiple-Arterial Versus Single-Arterial Coronary Bypass Grafting. | BACKGROUND: More than 90% of coronary artery bypass grafting (CABG) is performed with a single-arterial bypass graft (SABG), based on the left internal thoracic artery (ITA) with supplemental vein grafts. This practice, often justified by safety concerns with multiple-arterial grafting (MABG), defies evidence of improv... | ['Aged', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Databases, Factual', 'Female', 'Hospitalization', 'Humans', 'Male', 'Odds Ratio', 'Postoperative Complications', 'Retrospective Studies', 'Treatment Outcome'] | 29,453,002 | [['M01.060.116.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
CEO's challenge: balance fiscal solvency, service to poor. | Competitive practices and the prospective payment system are among factors challenging Catholic health care facilities' commitment to serve the poor and elderly and to provide individualized care. To concentrate their mission on services to the marginated and thus alienate other payer groups through inability to compet... | ['Catholicism', 'Ethics, Medical', 'Health Facility Administrators', 'Humans', 'Poverty', 'Social Justice', 'United States'] | 10,267,322 | [['K01.844.188.250'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['M01.526.070.490', 'M01.526.485.430', 'N02.360.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['I01.880.604.473.700', 'K01.752.566.479.830.750', 'N03.706.437.700', 'N05.350.... | ['Humanities [K]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Improving flavor metabolism of Saccharomyces cerevisiae by mixed culture with Wickerhamomyces anomalus for Chinese Baijiu making. | Yeasts are the most important microorganisms in the fermentation of Chinese Baijiu and the interaction of these yeasts could impact the quality of Baijiu. In this study, we initially characterized the Baijiu yeasts and evaluated their fermentation potential. Wickerhamomyces anomalus GZ3 and Saccharomyces cerevisiae G20... | ['Acetates', 'Alcoholic Beverages', 'Candida', 'Cell Culture Techniques', 'China', 'Coculture Techniques', 'Fermentation', 'Flavoring Agents', 'Food Industry', 'Pichia', 'Saccharomyces cerevisiae', 'Taste'] | 29,551,466 | [['D02.241.081.018', 'D10.251.400.045'], ['G07.203.100.100', 'J02.200.100'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['Z01.252.474.164'], ['E05.481.500.374'], ['G02.111.158.249', 'G03.191.249'], ['D26.650.294', 'D27.720... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Structure-activity relationship of propylene glycol alginate sodium sulfate derivatives for blockade of selectins binding to tumor cells. | Selectins dominate the formation of the metastasis niche and are considered important targets for exploring antimetastatic drugs. In this study, we evaluated the effect of the marine drug propylene glycol alginate sodium sulfate (PSS) and a series of PSS derivatives on P-, L- or E-selectin-mediated binding with tumor c... | ['Alginates', 'Anticoagulants', 'Cell Line, Tumor', 'Humans', 'Lung Neoplasms', 'Molecular Weight', 'Neoplasm Metastasis', 'Protein Binding', 'Selectins', 'Structure-Activity Relationship'] | 30,732,758 | [['D09.698.068'], ['D27.505.954.502.119'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['G02.494'], ['C04.697.650', 'C23.550.727.650'], ['G02.111.679', 'G03.808'], ['D12.776.395.550.200.700', 'D12.776.503.843', 'D12.776.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Anesthetic data processing--the Bad S?ckinger model]. | A cost-effective computer program for district hospitals has been developed to process data from anesthetic charts. Apart from monthly and annual statistics relevant to clinical anesthesia and hospital administration, the described system allows free data handling of all material stored in the data base. The possibilit... | ['Anesthesiology', 'Electronic Data Processing', 'Hospitals, Community', 'Software'] | 3,688,418 | [['H02.403.066'], ['L01.224.085'], ['N02.278.421.306'], ['L01.224.900']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Independent component analysis (ICA) algorithms for improved spectral deconvolution of overlapped signals in 1H NMR analysis: application to foods and related products. | The major challenge facing NMR spectroscopic mixture analysis is the overlapping of signals and the arising impossibility to easily recover the structures for identification of the individual components and to integrate separated signals for quantification. In this paper, various independent component analysis (ICA) al... | ['Algorithms', 'Carbonated Beverages', 'Food Analysis', 'Gas Chromatography-Mass Spectrometry', 'Honey', 'Least-Squares Analysis', 'Magnetic Resonance Spectroscopy', 'Protons', 'Tobacco Use Cessation Devices'] | 24,604,756 | [['G17.035', 'L01.224.050'], ['G07.203.100.300', 'J02.200.300'], ['E05.362', 'J01.576.423.850.100'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G07.203.300.581', 'J02.500.581'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['E05.196.867.519'], ['D01.248.497.300.459.700', 'D01.268.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Determinants and burden of chronic kidney disease in the population-based CoLaus study: a cross-sectional analysis. | BACKGROUND: Chronic kidney disease (CKD) represents an increasing health burden. We present the population-based prevalence of CKD and compare the CKD Epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD) equations to estimate the glomerular filtration rate, using the revised CKD classif... | ['Adult', 'Aged', 'Albuminuria', 'Biomarkers', 'Cardiovascular Diseases', 'Creatinine', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 2', 'Feeding Behavior', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Hypertension', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Prevalence', 'Progno... | 23,825,103 | [['M01.060.116'], ['M01.060.116.100'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D23.101'], ['C14'], ['D03.383.129.308.207'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.149', 'C19.246.300'], ['F01.145.113.547', 'F01.145.407', 'G07.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Association between fat mass, lean mass, and bone loss: the Dubbo Osteoporosis Epidemiology Study. | UNLABELLED: Lower body fat mass is a risk factor for bone loss at lumbar spine in postmenopausal women, but not in men. Body lean mass and fat mass were not associated with femoral neck bone loss in either gender.INTRODUCTION: Bone density and body mass are closely associated. Whole body lean mass (LM) and fat mass (FM... | ['Absorptiometry, Photon', 'Adipose Tissue', 'Aged', 'Anthropometry', 'Australia', 'Body Composition', 'Bone Density', 'Female', 'Femur Neck', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Organ Size', 'Osteoporosis', 'Risk Factors', 'Sex Factors', 'Thinness'] | 25,572,048 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['A10.165.114'], ['M01.060.116.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['Z01.639.100', 'Z01.678.100.373'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G11.427.100'], ['A02.835.232.043.150.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Repeatability of ocular biometry with IOLMaster 700 in subjects with clear lens. | PURPOSE: The purpose of the study was to assess the reproducibility of ocular biometry using the IOLMaster-700 in a healthy population.METHODS: This is a prospective, cross-sectional, observational reproducibility study. Ocular biometry was performed three times on each of 45 studied eyes. Flattest meridian (Kf) and th... | ['Adult', 'Anterior Chamber', 'Axial Length, Eye', 'Biometry', 'Corneal Topography', 'Cross-Sectional Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Interferometry', 'Male', 'Middle Aged', 'Prospective Studies', 'Reference Values', 'Reproducibility of Results', 'Tomography, Optical Coherence', 'Young Adult'] | 27,770,390 | [['M01.060.116'], ['A09.371.060.067'], ['A09.371.199', 'E01.370.600.115.100.660.500'], ['E05.318.740.225', 'N06.850.505.200'], ['E01.370.380.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Visceral artery aneurysms secondary to collateral circulation. | OBJECTIVE: To evaluate dilatation of visceral arteries secondary to anomalies and collateral circulation.DESIGN: Case report.SETTING: Department of Vascular Surgery, University Hospital.PATIENTS: Two patients with secondary visceral aneurysms were reported. First patient (case 1) had a mid-aortic dysplastic syndrome wi... | ['Adult', 'Aneurysm', 'Angiography', 'Aortography', 'Arteries', 'Blood Vessel Prosthesis', 'Celiac Artery', 'Collateral Circulation', 'Duodenum', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Pancreas', 'Polytetrafluoroethylene', 'Renal Artery', 'Tomography, X-Ray Computed'] | 8,950,858 | [['M01.060.116'], ['C14.907.055'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['A07.015.114'], ['E07.695.110'], ['A07.015.114.207'], ['G09.330.100.248'], ['A03.556.124.684.124', 'A03.556.875.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The high prevalence of symptomatic degenerative lumbar osteoarthritis in Chinese adults: a population-based study. | STUDY DESIGN: A population-based study.OBJECTIVE: To study the prevalence and features of symptomatic degenerative lumbar osteoarthritis in adults.SUMMARY OF BACKGROUND DATA: Lumbar osteoarthritis adversely affects individuals and is a heavy burden. There are limited data on the prevalence of lumbar osteoarthritis.METH... | ['Adult', 'Age Factors', 'Aged', 'Asian Continental Ancestry Group', 'China', 'Cross-Sectional Studies', 'Epidemics', 'Female', 'Humans', 'Logistic Models', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Occupational Health', 'Osteoarthritis, Spine', 'Population Surveillance', 'Prevalence', 'Risk ... | 24,825,154 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.686.508.200'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.290.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450',... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Quality of care and in-hospital outcomes in patients with coronary heart disease in rural and urban hospitals (from Get With the Guidelines-Coronary Artery Disease Program). | Previous studies have suggested that patients with coronary artery disease (CAD) in rural areas may have worse outcomes due to limited availability of specialists, fewer resources, and less institutional funding. Data were collected from hospitals participating in the Get With the Guidelines-Coronary Artery Disease Pro... | ['Aged', 'Cardiovascular Agents', 'Cohort Studies', 'Coronary Disease', 'Female', 'Guideline Adherence', 'Hospital Mortality', 'Hospitals, Rural', 'Hospitals, Urban', 'Humans', 'Length of Stay', 'Male', 'Myocardial Revascularization', 'Practice Guidelines as Topic', 'Quality of Health Care', 'United States'] | 20,102,907 | [['M01.060.116.100'], ['D27.505.954.411'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.647.250', 'C14.907.585.250'], ['N04.761.337', 'N05.715.360.395'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['N02.27... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Affinity manipulation of surface-conjugated RGD peptide to modulate binding of liposomes to activated platelets. | Platelet adhesion, activation and fibrinogen-mediated aggregation are primary events in vascular thrombosis and occlusion. An injectable delivery system that can carry thrombolytics selectively to the sites of active platelet aggregation has immense potential in minimally invasive targeted therapy of vascular occlusion... | ['Amino Acid Sequence', 'Blood Platelets', 'Humans', 'Lipids', 'Liposomes', 'Microscopy, Electron, Scanning', 'Molecular Sequence Data', 'Oligopeptides', 'Platelet Activation', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Surface Properties'] | 18,192,005 | [['G02.111.570.060', 'L01.453.245.667.060'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['L01.453.245.667'], ['D12.644.456'], ['G09.188.390... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Activation of extracellular signal-regulated kinases (ERKs) defines the first phase of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells. | Activation of ERK1 and ERK2 protein kinases has been implicated in diverse cellular processes, including the control of cell proliferation and cell differentiation (Marshall [1995] Cell 80:179). In human myeloblastoid leukemia HL60 cells rapid (ca. 15 min) but transient activation of ERK1/2 has been reported following ... | ['Antineoplastic Agents', 'Biomarkers', 'Blotting, Western', 'Calcitriol', 'Cell Cycle', 'Cell Differentiation', 'Cell Division', 'Cell Nucleus', 'Culture Media, Serum-Free', 'Cytoplasm', 'Enzyme Activation', 'Enzyme Inhibitors', 'Flavonoids', 'G1 Phase', 'HL-60 Cells', 'Humans', 'Immunoblotting', 'Kinetics', 'Lipopoly... | 11,169,731 | [['D27.505.954.248'], ['D23.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['G04.144'], ['G04.152'], ['G04.14... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of chlorinated organics on intermediates in the heme pathway and on uroporphyrinogen decarboxylase. | Experimental porphyria induced by PHAHs is characterized by a progressive reduction in the activity of UROD. After intoxication with TCDD, the most porphyrogenic compound known to date, the liver was the principal site of action, as regards both porphyrin accumulation (mostly uroporphyrin) and the degree of enzyme impa... | ['Animals', 'Carboxy-Lyases', 'Chlorobenzenes', 'Dioxins', 'Heme', 'Hexachlorobenzene', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Polychlorinated Dibenzodioxins', 'Uroporphyrinogen Decarboxylase', 'Xanthine Oxidase'] | 3,442,377 | [['B01.050'], ['D08.811.520.224.125'], ['D02.455.426.559.389.261', 'D02.455.526.439.202'], ['D02.309.500', 'D03.383.231'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D02.455.426.559.389.261.400', 'D02.455.526.439.202.400'], ['A03.620'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatopancreatic arterial ring: bilateral symmetric typology in human celiaco-mesenteric arterial system. | The celiac and mesenteric arterial system including the left gastric, splenic, common hepatic, and superior mesenteric arteries shows various types of origins, courses, ramifications and anastomoses. In order to explain the various expressions of this system, we have proposed a typological model, in which celiacomesent... | ['Aged', 'Aged, 80 and over', 'Arteries', 'Celiac Artery', 'Duodenum', 'Female', 'Hepatic Artery', 'Humans', 'Liver', 'Liver Circulation', 'Male', 'Mesenteric Arteries', 'Pancreas', 'Splenic Artery', 'Stomach'] | 12,530,508 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114'], ['A07.015.114.207'], ['A03.556.124.684.124', 'A03.556.875.249'], ['A07.015.114.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['G09.330.100.881.552'], ['A07.015.114.565'], ['A03.734'], ['A07.015.114.814'], ['A03.556.875.875']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Central vocal cord paralysis and paresis presenting as laryngeal stridor in children. | Vocal cord paralysis or paresis as the initial presenting symptom for intracranial tumors in children are rare. Recently, two pediatric patients who were later diagnosed as having intracranial tumors presented with the symptom of voice changes and stridor. Telescopic examination revealed bilateral vocal cord paresis an... | ['Brain Neoplasms', 'Brain Stem', 'Child, Preschool', 'Cranial Fossa, Posterior', 'Female', 'Glioma', 'Histiocytosis, Langerhans-Cell', 'Humans', 'Laryngeal Nerves', 'Laryngoscopy', 'Medulla Oblongata', 'Respiratory Sounds', 'Rotation', 'Videotape Recording', 'Vocal Cord Paralysis'] | 2,293,696 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.132'], ['M01.060.406.448'], ['A01.456.830.200', 'A02.835.232.781.750.400'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['C08.381.483.375', 'C15.604.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins. | Susceptibility to multiple sclerosis (MS) is associated with certain MHC class II haplotypes, in particular HLA-DR2. Two DR beta chains, DRB1*1501 and DRB5*0101, are co-expressed in the HLA-DR2 haplotype, resulting in the formation of two functional cell surface heterodimers, HLA-DR2a (DRA*0101, DRB5*0101) and HLA-DR2b... | ['Alleles', 'Amino Acid Sequence', 'Binding Sites', 'Crystallography, X-Ray', 'HLA-DR2 Antigen', 'Humans', 'Immunodominant Epitopes', 'Models, Molecular', 'Molecular Sequence Data', 'Multiple Sclerosis', 'Myelin Basic Protein', 'Peptide Fragments', 'Protein Conformation', 'Protein Subunits', 'Receptors, Antigen, T-Cell... | 11,080,454 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['D12.776.395.550.509.400.440.400.020', 'D12.776.543.550.440.400.440.400.020', 'D23.050.301.500.400.400.440.400.020', 'D23.050.301.500.450.400.440.389.750', 'D23.050.705.552.410.400.440.389.020', 'D23... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A meta-analysis of safety and effectiveness of perioperative beta-blocker use for the prevention of cardiac events in different types of noncardiac surgery. | OBJECTIVE: Perioperative beta-blocker therapy has been proposed to improve outcome. Most of the trials conducted, however, lacked statistical power to evaluate the incidence of hard cardiac events and the relationship to the type of surgery. Therefore, we conducted a meta-analysis of all randomized controlled trials in... | ['Adrenergic beta-Antagonists', 'Death, Sudden, Cardiac', 'Humans', 'Myocardial Ischemia', 'Perioperative Care', 'Surgical Procedures, Operative'] | 16,474,237 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['C14.280.383.220', 'C23.550.260.322.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647', 'C14.907.585'], ['E02.760.731', 'E04.604', 'N02.421.585.722'], ['E04']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Plasmatic concentrations of fluoxetine, pharmacokinetics, therapeutic response and side effects]. | The kinetics of fluoxetine and possible relations between the drug's plasmatic concentration and therapeutic response and side effects were evaluated in a sample of 66 depressive patients, 26 men and 40 women, average age 46.6 years (SD = 14.1), diagnosed according to DSM-III criteria and evaluated using the Hamilton s... | ['Adolescent', 'Adult', 'Aged', 'Ambulatory Care', 'Antidepressive Agents, Tricyclic', 'Dose-Response Relationship, Drug', 'Female', 'Fluoxetine', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Severity of Illness Index'] | 8,213,289 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.954.427.700.122.055'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.092.831.280'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['F04.711.513.653'], ['E05.318... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Carriage of multidrug-resistant Streptococcus pneumoniae and impact of chemoprophylaxis during an outbreak of meningitis at a day care center. | Three cases of meningitis due to multidrug-resistant serotype 14 Streptococcus pneumoniae occurred at a day care center (DCC) over 5 days. Cultures of nasopharyngeal samples were done at the index DCC, 2 comparison DCCs, and a pediatrics practice. Isolates were serotyped and subtyped by pulsed-field gel electrophoresis... | ['Bacterial Vaccines', 'Carrier State', 'Child', 'Child Day Care Centers', 'Child, Preschool', 'Disease Outbreaks', 'Drug Resistance, Microbial', 'Drug Resistance, Multiple', 'Female', 'Humans', 'Infant', 'Male', 'Meningitis, Pneumococcal', 'Nasopharynx', 'Patient Compliance', 'Pneumococcal Vaccines', 'Streptococcus pn... | 10,524,972 | [['D20.215.894.135'], ['N06.850.520.169'], ['M01.060.406'], ['J03.160', 'N02.421.143.098'], ['M01.060.406.448'], ['N06.850.290'], ['G06.225', 'G07.690.773.984.269'], ['G07.690.773.984.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.150.252.223.500.875', 'C01.150.252.410.890.670.595', 'C01... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Comparing face processing strategies between typically-developed observers and observers with autism using sub-sampled-pixels presentation in response classification technique. | In the present study we modified the standard classification image method by subsampling visual stimuli to provide us with a technique capable of examining an individual's face-processing strategy in detail with fewer trials. Experiment 1 confirmed that one testing session (1450 trials) was sufficient to produce classi... | ['Adult', 'Autistic Disorder', 'Contrast Sensitivity', 'Discrimination, Psychological', 'Face', 'Female', 'Humans', 'Male', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Sensory Thresholds', 'Young Adult'] | 23,321,026 | [['M01.060.116'], ['F03.625.164.113.500'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['F02.463.593.257'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['F0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of Granulocyte-Macrophage Colony-Stimulating Factor With or Without Supervised Exercise on Walking Performance in Patients With Peripheral Artery Disease: The PROPEL Randomized Clinical Trial. | Importance: Benefits of granulocyte-macrophage colony-stimulating factor (GM-CSF) for improving walking ability in people with lower extremity peripheral artery disease (PAD) are unclear. Walking exercise may augment the effects of GM-CSF in PAD, since exercise-induced ischemia enhances progenitor cell release and may ... | ['Aged', 'Combined Modality Therapy', 'Exercise Therapy', 'Female', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'Intermittent Claudication', 'Lower Extremity', 'Male', 'Middle Aged', 'Peripheral Arterial Disease', 'Stem Cells', 'Walk Test', 'Walking'] | 29,141,087 | [['M01.060.116.100'], ['E02.186'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['D12.644.276.374.410.240.375', 'D12.776.395.240.300', 'D12.776.467.374.410.240.375', 'D23.529.374.410.240.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.137.126.669', 'C23.888.531'], ['A01.378.610'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression. | Chronic hepatitis C virus (HCV) infection is associated with chronic inflammation of liver, which leads to the development of cirrhosis and hepatocellular carcinoma (HCC). Because of severe side effects and only a 50-70% cure rate in genotype 1 HCV-infected patients upon current standard treatment with pegylated interf... | ['Antiviral Agents', 'Catechin', 'Cell Line', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cytidine', 'Drug Therapy, Combination', 'Drugs, Chinese Herbal', 'Hepacivirus', 'Humans', 'Interferon-alpha', 'NF-kappa B', 'Oligopeptides', 'Signal Transduction', 'Viral Nonstructural Proteins', 'Virus Replication'] | 21,692,943 | [['D27.505.954.122.388'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['A11.251.210'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TSE agent strains and PrP: reconciling structure and function. | The molecular structures of the infectious agents that cause transmissible spongiform encephalopathy (TSE) diseases are still not known despite the current wide acceptance of the prion hypothesis as the basis for their resolution. Here, data supporting and challenging the prion hypothesis in relation to both the bioche... | ['Animals', 'PrPSc Proteins', 'Prion Diseases', 'Prions', 'Structure-Activity Relationship'] | 12,468,229 | [['B01.050'], ['D12.776.785.340.750'], ['C01.207.800', 'C10.228.228.800', 'C10.574.843'], ['D12.776.785'], ['G02.111.830', 'G07.690.773.997']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a statistical model to identify spatial and meteorological drivers of elevated O3 in Nevada and its application to other rural mountainous regions. | Measurements of O3 at relatively remote monitoring sites are useful for quantifying baseline O3, and subsequently the magnitude of O3 not controllable by local regulations. As the National Ambient Air Quality Standard (NAAQS) for O3 becomes more stringent, there is an increased need to quantify baseline O3 particularly... | ['Air Pollutants', 'Air Pollution', 'Environmental Monitoring', 'Meteorological Concepts', 'Models, Chemical', 'Models, Statistical', 'Nevada', 'Ozone'] | 25,895,623 | [['D27.888.284.101'], ['N06.850.460.100'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.750', 'N06.230.300'], ['E05.599.495'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['Z01.107.567.875.760.550'], ['D01.362.670.600']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A legislative perspective on the school nurse and education for children with disabilities in New Jersey. | The New Jersey Dept. of Education has proposed a new direction for interpreting the "Education for All Handicapped Children Act of 1975" (Public Law 94-142). If implemented, a new and broader scope of addressing learning and/or behavior and health problems for the school-aged child will be provided. In this article, th... | ['Child', 'Disabled Persons', 'Education, Special', 'History, 20th Century', 'Humans', 'New Jersey', 'Rehabilitation', 'School Nursing'] | 1,839,322 | [['M01.060.406'], ['M01.150'], ['I02.233.213'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.500.525'], ['E02.760.169.063.500', 'E02.831', 'H02.403.680.600', 'N02.421.784'], ['H02.478.676.824', 'N02.421.726.809.742']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Nutritional and Health-Related Effects of a Diet Containing Apple Seed Meal in Rats: The Case of Amygdalin. | Apple pomace includes seeds that are rich in protein, fiber, and oil, which can be extracted from them. However, they can also contain a significant amount of toxigenic amygdalin. We hypothesized that amygdalin is a compound that significantly reduces the nutritional and health quality of defatted apple seeds. An exper... | ['Amygdalin', 'Animal Feed', 'Animals', 'Diet', 'Male', 'Malus', 'Nutritive Value', 'Rats', 'Rats, Wistar', 'Seeds'] | 28,974,035 | [['D02.626.175', 'D09.408.348.050'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G07.203.650.240'], ['B01.650.940.800.575.912.250.859.937.500.444'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.90... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Sexual abuse histories of adolescent male sex offenders: differences on the basis of the age and gender of their victims. | Childhood sexual abuse has often been implicated in the etiology of adolescent sex offending behavior. Victimization rates in the literature vary according to whether data are collected prior (22%) or subsequent (52%) to treatment. Previous research suggests that the incidence of sexual abuse varies as a function of vi... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Age Factors', 'Child', 'Child Abuse, Sexual', 'Female', 'Humans', 'Male', 'Sex Factors', 'Sex Offenses', 'Socioeconomic Factors'] | 8,530,763 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N05.715.350.675', 'N06.850.490.875'], ['I01.198.240.748'], ['I01.880.853.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Symptoms of major depression and tricyclic side effects in primary care patients. | OBJECTIVE: To examine the prevalence and course of symptoms resembling side effects of tricyclic antidepressants among primary care patients experiencing major depression and receiving nortriptyline pharmacotherapy.DESIGN: Prospective cohort study.PATIENTS: Seventy-five patients meeting DSM-III-R criteria for a current... | ['Adolescent', 'Adult', 'Aged', 'Analysis of Variance', 'Antidepressive Agents, Tricyclic', 'Cognition Disorders', 'Cohort Studies', 'Depressive Disorder', 'Diagnosis, Differential', 'Digestive System Diseases', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Nortriptyline', 'Primary Health Care'... | 9,159,697 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.954.427.700.122.055'], ['F03.615.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F03.600.300'], ['E01.171'], ['C06'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Response to dietary nitrogen in ponies. | Utilisation of nitrogen was studied in 4 crossbred ponies. A latin square design was used to study the effects of corn gluten meal, casein or urea when added to a low protein basal diet. Apparent nitrogen digestion, nitrogen retention, total plasma protein, plasma urea and plasma-free amino acids were measured. The add... | ['Amino Acids', 'Animal Feed', 'Animals', 'Blood Urea Nitrogen', 'Caseins', 'Horses', 'Nitrogen', 'Urea', 'Zea mays'] | 631,109 | [['D12.125'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.984.235.472'], ['D01.268.604', 'D01.362.625'], ['D02.065.950'], ['B01.650.940.800.575.912.250.822.96... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Statistical properties of color-signal spaces. | In applications of principal component analysis (PCA) it has often been observed that the eigenvector with the largest eigenvalue has only nonnegative entries when the vectors of the underlying stochastic process have only nonnegative values. This has been used to show that the coordinate vectors in PCA are all located... | ['Algorithms', 'Color', 'Colorimetry', 'Computer Simulation', 'Models, Statistical', 'Pattern Recognition, Automated', 'Spectrum Analysis'] | 15,898,541 | [['G17.035', 'L01.224.050'], ['G01.590.540.199'], ['E05.196.922.250'], ['L01.224.160'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['L01.399.750'], ['E05.196.867']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Scherzer's formula and the correction of spiral distortion in the electron microscope. | Scherzer's general expression of 1937 for the spiral distortion coefficient of electron lenses is used to calculate the spiral distortion of the rectangular-field model for the axial flux density distribution in magnetic projector lenses. The results show why it is difficult to correct the spiral distortion produced by... | ['Lenses', 'Microscopy, Electron', 'Models, Theoretical', 'Optics and Photonics'] | 888,237 | [['E07.632.500'], ['E01.370.350.515.402', 'E05.595.402'], ['E05.599'], ['H01.671.617', 'J01.293.688']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A novel method for amino starch preparation and its adsorption for Cu(II) and Cr(VI). | A novel method was proposed to prepare amino starch by reacting ethylenediamine with previously synthesized dialdehyde starch. Different factors affecting the preparation, i.e., ethylenediamine concentration, ethylenediamine:dialdehyde starch molar ratio, pH, duration and temperature have been studied. The modified sta... | ['Adsorption', 'Amines', 'Chromium', 'Conservation of Natural Resources', 'Copper', 'Ethylenediamines', 'Metals, Heavy', 'Methods', 'Starch', 'Thermodynamics'] | 20,605,326 | [['G01.030', 'G02.020'], ['D02.092'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['J01.256', 'N06.230.080'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.092.782.258.368'], ['D01.268.556', 'D01.552.544'], ['E05.581'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855'], ['G01.9... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
How Often Are Study Design and Level of Evidence Misreported in the Pediatric Orthopaedic Literature? | BACKGROUND: Observational studies are the most commonly used study designs in the pediatric orthopaedic literature. The differences between observational study designs are important but not widely understood, leading to potential discrepancies between the reported and actual study design. Study design misclassification... | ['Biomedical Research', 'Child', 'Evidence-Based Medicine', 'Humans', 'Journal Impact Factor', 'Observational Studies as Topic', 'Orthopedics', 'Pediatrics', 'Research Design'] | 31,770,169 | [['H01.770.644.145'], ['M01.060.406'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.099.325.500', 'L01.453.183.291.500'], ['E05.318.372.250.500', 'N05.715.360.330.250.500', 'N06.850.520.450.250.500'], ['H02.403.810.494'], ['H02.403.670'], ['E05.581.500', 'H01.770.64... | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Thiols and polyamines in the potentiation of malathion toxicity in larval stages of the toad Bufo arenarum. | Treatment with exogenous spermidine enhanced acute malathion toxicity during larval development of the toad Bufo arenarum Hensel. The polyamine was rapidly incorporated in the larvae with a subsequent metabolization to putrescine and spermine, which were excreted to the media. Endogenous polyamine levels were not chang... | ['Animals', 'Biological Availability', 'Biotransformation', 'Bufo arenarum', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Glutathione Disulfide', 'Larva', 'Lipid Peroxidation', 'Malathion', 'Oxidation-Reduction', 'Pesticide Synergists', 'Spermidine', 'Sulfhydryl Compounds'] | 11,574,288 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['B01.050.150.900.090.180.210.080'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968.477'], ['D12.644.456.448.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G02.111.515', 'G03.295.531.587'], ['D02.705.400.62... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The parasellar osteo-dural chamber and the vascular and neural elements that traverse it. An anatomical concept that would replace the cavernous sinus of classical anatomy]. | On each side of the sella turcica, because of the existence of vascular and nervous elements, the two aspects of the parasellar segment of the tentorium cerebelli diverge and with the wall of the sphenoid bone form an extradural lodge. In this space are included a venous pathway (the cavernous sinus of the classics), t... | ['Abducens Nerve', 'Arachnoid', 'Carotid Artery, Internal', 'Cavernous Sinus', 'Dura Mater', 'Humans', 'Oculomotor Nerve', 'Optic Nerve', 'Sella Turcica', 'Terminology as Topic', 'Trochlear Nerve', 'Veins'] | 2,277,656 | [['A08.800.800.120.030'], ['A08.186.566.166'], ['A07.015.114.186.200.230'], ['A07.015.908.224.334'], ['A08.186.566.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.050.050.650', 'A08.800.050.600.475', 'A08.800.800.060.650', 'A08.800.800.120.600'], ['A08.800.800.120.680'], ['A02.835.232.781.802.662'], [... | ['Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pharmacokinetics of tolfenamic acid: disposition in bile, blood and urine after intravenous administration to man. | To study its pharmacokinetics and especially microCi/100 mg was infused i.v. in 8 patients with a T-tube inserted in the common bile duct at choledocholithotomy 7-10 days prior to the study. Bile was collected in fractions by continuous suction over a 24 h period. Blood samples were taken and urine collected up to 48 h... | ['Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Bile', 'Carbon Radioisotopes', 'Female', 'Humans', 'Infusions, Parenteral', 'Kinetics', 'Metabolic Clearance Rate', 'Middle Aged', 'ortho-Aminobenzoates'] | 6,334,608 | [['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['A12.200.087'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510'], ['G01.374.661', 'G02.111.490'], ['E01.370.225.843', 'E05.200.843'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors and familial clustering for fever 7-10days after the first dose of measles vaccines. | BACKGROUND: Seven to ten days after a first dose of a measles-containing vaccine (MCV; i.e., MMR or MMRV), children have elevated fever risk which can be associated with febrile seizures. This study investigated individual and familial factors associated with fever 7-10days after MCV.METHODS: Retrospective cohort study... | ['Child, Preschool', 'Cluster Analysis', 'Family Health', 'Female', 'Fever', 'Humans', 'Infant', 'Male', 'Measles Vaccine', 'Retrospective Studies', 'Risk Factors'] | 28,233,624 | [['M01.060.406.448'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N01.400.300'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D20.215.894.899.404'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action. | Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model sy... | ['Anti-Bacterial Agents', 'Arabidopsis', 'Ciprofloxacin', 'DNA Gyrase', 'Escherichia coli', 'Herbicides', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Topoisomerase II Inhibitors'] | 29,388,638 | [['D27.505.954.122.085'], ['B01.650.940.800.575.912.250.157.100'], ['D03.633.100.810.835.322.186'], ['D08.811.399.403.741.149', 'D12.776.097.237'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.720.031.700.366', 'D27.888.723.366'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G02.111... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
APOBEC3G has the ability to programme T cell plasticity. | Recently Apolipoprotein B mRNA editing enzyme, Catalytic Polypeptide-like 3G (APOBEC3G) biology has assumed importance because of its role in oncogenesis. In this context, the present study was addressed to understand the immune-modulatory role of APOBEC3G through its effect upon the T-cell plasticity phenomenon. Such ... | ['APOBEC-3G Deaminase', 'Cell Plasticity', 'Gene Expression Regulation', 'Humans', 'Immunomodulation', 'Interleukins', 'NF-kappa B', 'STAT3 Transcription Factor', 'T-Lymphocytes', 'Transfection'] | 27,282,578 | [['D08.811.277.151.486.250.500.750'], ['G04.356.250'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465', 'G12.535'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['D12.644.360.024.342.300', 'D12.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Game-theoretic approach to joint transmitter adaptation and power control in wireless systems. | Game theory has emerged as a new mathematical tool in the analysis and design of wireless communication systems, being particularly useful in studying the interactions among adaptive transmitters that attempt to achieve specific objectives without cooperation. In this paper, we present a game-theoretic approach to the ... | ['Algorithms', 'Computer Communication Networks', 'Computer Simulation', 'Decision Support Techniques', 'Electric Power Supplies', 'Energy Transfer', 'Game Theory', 'Models, Theoretical', 'Signal Processing, Computer-Assisted', 'Wireless Technology'] | 19,906,589 | [['G17.035', 'L01.224.050'], ['L01.224.230.110'], ['L01.224.160'], ['E05.245', 'L01.313.500.750.190'], ['E07.305.124'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['G17.388'], ['E05.599'], ['L01.224.800'], ['L01.178.847.950']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Collaborative Interpersonal Psychotherapy for HIV-Positive Women in Kenya: A Case Study From the Mental Health, HIV and Domestic Violence (MIND) Study. | We examine the efficacy of nonspecialists delivering interpersonal psychotherapy (IPT) to HIV-positive (HIV+) women. We describe a case in which local personnel without prior mental health training delivered IPT for the treatment of depression and posttraumatic stress disorder in an HIV+ woman who reported experiencing... | ['Adult', 'Depressive Disorder, Major', 'Female', 'HIV Seropositivity', 'Humans', 'Interpersonal Relations', 'Kenya', 'Psychotherapy', 'Stress Disorders, Post-Traumatic'] | 27,463,639 | [['M01.060.116'], ['F03.600.300.375'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.673.480.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['Z01.058.290.120.400'], ['F04.754'], ['F03.950.750.500']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Plasma-based circulating MicroRNA biomarkers for Parkinson's disease. | BACKGROUND: The current "gold-standard" for Parkinson's disease (PD) diagnosis is based primarily on subjective clinical rating scales related with motor features. Molecular biomarkers that are objective and quantifiable remain attractive as clinical tools to detect PD prior to its motor onsets.OBJECTIVE: Here, we aime... | ['Aged', 'Aged, 80 and over', 'Biomarkers', 'Female', 'Humans', 'Male', 'MicroRNAs', 'Middle Aged', 'Parkinson Disease', 'Sensitivity and Specificity'] | 23,938,262 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Argyrophil and beta-endorphin immunoreactive cells in focal islet-cell adenomatosis and insulin-producing islet-cell adenomata. | Pancreatic tissue from 3 cases of hyperinsulinemic hypoglycemia was examined using histochemical and immunoperoxidase staining techniques. The insular lesions present were adenomatosis and insulin-producing islet-cell adenomata. The great majority of the islet parenchymal cells in these lesions were reactive with antib... | ['Adenoma', 'Adenoma, Islet Cell', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Hypoglycemia', 'Immunoenzyme Techniques', 'Immunohistochemistry', 'Infant', 'Insulin', 'Insulin Secretion', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Radioimmunoassay', 'beta-Endorphin'] | 1,963,254 | [['C04.557.470.035'], ['C04.557.470.035.100', 'C04.588.274.761.249', 'C04.588.322.475.249', 'C06.301.761.249', 'C06.689.667.249', 'C19.344.421.249'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['E05.478.566.350', 'E05.478... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential effects of the tyrosine kinase inhibitors on collagen type 1-induced platelet aggregation and adhesion to this protein. | Herbimycin A, lavendustin A, and methyl 2,5-dihydroxycinnamate were used to study the role of protein tyrosine kinases in collagen-platelet interaction. All three compounds produced a concentration dependent inhibition of platelet aggregation induced by collagen type I, characterized by values of IC50 equaled to 0.9, 1... | ['Benzoquinones', 'Cinnamates', 'Collagen', 'Cross-Linking Reagents', 'Drug Synergism', 'Humans', 'Lactams, Macrocyclic', 'Phenols', 'Platelet Adhesiveness', 'Platelet Aggregation', 'Protein-Tyrosine Kinases', 'Quinones', 'Rifabutin'] | 9,187,017 | [['D02.806.250'], ['D02.241.223.200'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D27.720.470.410.210'], ['G07.690.773.968.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.327', 'D04.345.295'], ['D02.455.426.559.389.657'], ['G09.188.390.600.500', 'G09.188.670'], ['G09.188.370.687', 'G09.188.390.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overweight and obesity among Alaskan Eskimos of the Bering Straits Region: the Alaska Siberia project. | OBJECTIVE: To document the height, weight, BMI and prevalence of obesity for Eskimo residents of four villages of the Bering Straits Region of Alaska.DESIGN AND SUBJECTS: 454 Non-pregnant residents over 24 y of age, with at least one Eskimo grandparent participated in one cross sectional survey within each village.MEAS... | ['Adult', 'Aged', 'Alaska', 'Asian Continental Ancestry Group', 'Body Height', 'Body Mass Index', 'Body Weight', 'Cross-Sectional Studies', 'Female', 'Humans', 'Inuits', 'Male', 'Middle Aged', 'Nutrition Surveys', 'Obesity', 'Prevalence', 'Sex Factors'] | 10,951,530 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.875.580.100'], ['M01.686.508.200'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.10... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Research in neurosurgical journals. | This study seeks to identify trends in the nature of papers published in the neurosurgical literature by reviewing all papers published in Journal of Neurosurgery, Neurosurgery, British Journal of Neurosurgery (1990 only), Acta Neurochirurgica and Journal of Neurology, Neurosrugery and Psychiatry (neurosurgical only) i... | ['Evaluation Studies as Topic', 'Neurosurgery', 'Periodicity', 'Research', 'Research Design', 'Research Support as Topic'] | 1,562,298 | [['E05.337', 'N05.715.360.335'], ['H02.403.810.425'], ['G01.910.645', 'G07.180.562'], ['H01.770.644'], ['E05.581.500', 'H01.770.644.728'], ['N03.219.483.645']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Acclimation of Emiliania huxleyi (1516) to nutrient limitation involves precise modification of the proteome to scavenge alternative sources of N and P. | Limitation of marine primary production by the availability of nitrogen or phosphorus is common. Emiliania huxleyi, a ubiquitous phytoplankter that plays key roles in primary production, calcium carbonate precipitation and production of dimethyl sulfide, often blooms in mid-latitude at the beginning of summer when inor... | ['Acclimatization', 'Alkaline Phosphatase', 'Amino Acids', 'Biomass', 'Calcium Carbonate', 'Haptophyta', 'Nitrogen', 'Phosphates', 'Phosphorus', 'Phytoplankton', 'Polyamines', 'Proteome', 'Sulfides', 'Urea'] | 26,119,724 | [['G07.025.133', 'G16.012.500.133'], ['D08.811.277.352.650.035'], ['D12.125'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['B01.400'], ['D01.268.604', 'D01.362.625'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['D01.268.666'], ['B05... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Effect of stress and intesity of mobile phone using on the health and subjective symptoms in GSM workers]. | BACKGROUND: There are no available data on the health consequences that may result from the synergistic effects of electromagnetic fields (EMF) and stress. Understanding the mechanisms of the simultaneous exposure will make it possible to develop procedures to minimize adverse health effects in professionals using mobi... | ['Adult', 'Burnout, Professional', 'Cell Phone', 'Electromagnetic Fields', 'Environmental Exposure', 'Fatigue', 'Female', 'Headache', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Poland', 'Sleep Wake Disorders', 'Surveys and Questionnaires', 'Telecommunications', 'Young Adult'] | 28,731,073 | [['M01.060.116'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['L01.178.847.698.300'], ['G01.358.500.260', 'G01.358.750.500'], ['N06.850.460.350'], ['C23.888.369'], ['C23.888.592.612.441'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Hydroxy-1-aryl-isochromans: protective compounds against lipid peroxidation and cellular nitrosative stress. | Hydroxy-1-aryl-isochromans are a novel class of polyphenolic heterocyclic compounds with potent antioxidative potential. Here we investigated the protective effects of hydroxy-1-aryl-isochroman derivatives against lipid peroxidation and nitrosative stress as a function of their degree of hydroxylation. Measurements of ... | ['Animals', 'Antioxidants', 'Brain', 'Chromans', 'Lipid Peroxidation', 'Microglia', 'Mitochondria', 'Oxidative Stress', 'Rats', 'Thiobarbituric Acid Reactive Substances'] | 18,284,848 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A08.186.211'], ['D03.383.663.283.240', 'D03.633.100.150.240'], ['G02.111.515', 'G03.295.531.587'], ['A08.637.400', 'A11.650.400'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G03.673', 'G07.775.750'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Childhood obesity. Recommendations of the Nutrition Committee of the Spanish Association of Pediatrics. Part I. Prevention. Early detection. Role of the pediatrician]. | Obesity is a pathologic entity characterized by an increase in fat body mass and is a global public health problem. In Spain, between 1984 (the Paidos study) and 2000 (the enKid study), the prevalence of childhood overweight and obesity increased and significant differences were found among the autonomous communities. ... | ['Child', 'Diet', 'Early Diagnosis', 'Humans', 'Obesity', 'Pediatrics', 'Risk Factors'] | 17,194,329 | [['M01.060.406'], ['G07.203.650.240'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['H02.403.670'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantum dots assisted laser desorption/ionization mass spectrometric detection of carbohydrates: qualitative and quantitative analysis. | A quantum dots (QDs) assisted laser desorption/ionization mass spectrometric (QDA-LDI-MS) strategy was proposed for qualitative and quantitative analysis of a series of carbohydrates. The adsorption of carbohydrates on the modified surface of different QDs as the matrices depended mainly on the formation of hydrogen bo... | ['Adsorption', 'Blood Glucose', 'Carbohydrates', 'Humans', 'Hydrogen Bonding', 'Quantum Dots', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 27,041,659 | [['G01.030', 'G02.020'], ['D09.947.875.359.448.500'], ['D09'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['E07.705', 'J01.637.512.600.650'], ['E05.196.566.755']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The categorical distinction of vowel and consonant representations: evidence from dysgraphia. | Subject GSI presents with a graphemic buffer deficit following a massive left fronto-parietal lesion. His errors involved essentially only consonants (98.2%). However, he always spelled correctly the first consonant in a string, and produced steadily increasing numbers of errors on the following consonants, while alway... | ['Adult', 'Agraphia', 'Aphasia, Broca', 'Handwriting', 'Hemiplegia', 'Humans', 'Language', 'Male', 'Memory, Short-Term', 'Psychomotor Performance', 'Stroke'] | 15,788,250 | [['M01.060.116'], ['C10.597.606.150.500.050', 'C23.888.592.604.150.500.050'], ['C10.597.606.150.500.800.100.100', 'C23.888.592.604.150.500.800.100.100'], ['L01.559.423.906.539'], ['C10.597.622.295', 'C23.888.592.636.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F02.463.425.54... | ['Named Groups [M]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor. | Transgenic mice expressing transforming growth factor alpha (TGF-alpha) in type II cells under control of the lung-specific surfactant protein-C (SP-C) promoter develop pulmonary fibrosis and marked airspace hypoplasia. To identify cellular signaling mechanisms involved in lesion formation, we generated transgenic mice... | ['Animals', 'ErbB Receptors', 'Gene Expression Regulation', 'Gene Transfer Techniques', 'Humans', 'Lung', 'Mice', 'Mice, Transgenic', 'Mutation', 'Pulmonary Fibrosis', 'Transforming Growth Factor alpha'] | 8,879,184 | [['B01.050'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['G05.308'], ['E05.393.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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