Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[The relation of heart rate variability and a dispersive electrocardiogram mapping indicators in human during fixed rate breathing test]. | Association of heart rate variability and dispersive electrocardiogram mapping indicators in women during fixed rate breathing test by the period of 10 s are observed. Disturbance of depolarization processes in auricles that show an increase in dispersive group G1 is associated with expressed vagal reserves deficiency.... | ['Breath Tests', 'Electrocardiography', 'Electrophysiologic Techniques, Cardiac', 'Electrophysiological Phenomena', 'Female', 'Heart', 'Heart Rate', 'Humans', 'Metabolism', 'Middle Aged', 'Respiratory Rate', 'Vagus Nerve'] | 23,013,004 | [['E01.370.100'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.370.380.245', 'E01.370.405.267'], ['G07.265'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03'], ['M01.060.116.630'], ['E01.370.600.875.875', 'G09.772.705.730'], ['A08.800.050.050.925... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Generating controlled image sets in cognitive neuroscience research. | The investigation of perceptual and cognitive functions with non-invasive brain imaging methods critically depends on the careful selection of stimuli for use in experiments. For example, it must be verified that any observed effects follow from the parameter of interest (e.g. semantic category) rather than other low-l... | ['Brain', 'Brain Mapping', 'Cognition', 'Cognitive Science', 'Food', 'Humans', 'Imagination', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Research', 'Set, Psychology', 'Spectrum Analysis'] | 18,338,244 | [['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.188'], ['F04.096.628.255'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.634'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['H01.770.644'], ['F02.463... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Thanatophoric dwarfism; drugs and antenatal diagnosis; a case report. | Thanatophoric dwarfism is not as rare as once thought. We present this case because of the possible association with drug administration and the probability of diagnosing this condition antenatally. | ['Abnormalities, Drug-Induced', 'Amitriptyline', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Phenobarbital', 'Phenytoin', 'Pregnancy', 'Prenatal Diagnosis', 'Thanatophoric Dysplasia'] | 1,995,385 | [['C16.131.042'], ['D02.455.426.559.847.181.384.100', 'D04.615.181.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D03.383.742.698.253.650'], ['D03.383.129.308.432.555.730'], ['G08.686.784.769'], ['E01.370.378.630'], ['C05.116.099.343.110.500', 'C05.116.099.708.017.500', 'C05.660.585.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Immunoreactive insulin in the blood of pregnant women with different disorders of glucose tolerance]. | The authors studied the content of immunoreactive insulin (IRI) during the glucose tolerance test (GTT) in 57 pregnant women at various periods of pregnancy and in 10 nonpregnant women at the same age. There proved to be a significant increase in IRI in the blood on fasting stomach and during the GTT in all the pregnan... | ['Adult', 'Antigens', 'Blood Glucose', 'Body Weight', 'Female', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Pregnancy', 'Pregnancy in Diabetics'] | 1,023,187 | [['M01.060.116'], ['D23.050'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
M?s-o-menos: a simple sign averaging method for discrimination in genomic data analysis. | MOTIVATION: The successful translation of genomic signatures into clinical settings relies on good discrimination between patient subgroups. Many sophisticated algorithms have been proposed in the statistics and machine learning literature, but in practice simpler algorithms are often used. However, few simple algorith... | ['Algorithms', 'Breast Neoplasms', 'Female', 'Gene Expression Profiling', 'Genomics', 'Humans', 'Ovarian Neoplasms', 'Survival Analysis', 'Urinary Bladder Neoplasms'] | 25,061,068 | [['G17.035', 'L01.224.050'], ['C04.588.180', 'C17.800.090.500'], ['E05.393.332'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E05.318.740.998', 'N05.715.360.750... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Crystallization kinetics of organogels prepared by rice bran wax and vegetable oils. | Rice bran wax (RBX) obtained during rice bran oil purification can form organogels in edible oils. The kinetics of crystallization and the viscous properties of RBX organogels were studied using differential scanning calorimetry (DSC), viscosity changes with varying temperature, hardness measurements by penetrometry, a... | ['Anisotropy', 'Crystallization', 'Gels', 'Hardness', 'Plant Oils', 'Rice Bran Oil', 'Temperature', 'Viscosity', 'Waxes', 'X-Ray Diffraction'] | 22,188,800 | [['G01.590.040', 'G02.050'], ['E05.196.300', 'G02.171'], ['D20.280.320', 'D26.255.165.320'], ['G01.374.647'], ['D10.627.700', 'D20.215.784.750'], ['D10.627.700.819', 'D20.215.784.750.784'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G02.930'], ['D1... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Etiology and antimicrobial resistance patterns in early and late neonatal sepsis in a Neonatal Intensive Care Unit. | INTRODUCTION: Neonatal sepsis is one of the main causes of death among newborn infants. Empirical antimicrobial treatment is based on epidemiological information and antimicrobial susceptibility tests. The objective of this study was to describe etiologic agents and their antimicrobial susceptibility among newborn infa... | ['Age Factors', 'Anti-Bacterial Agents', 'Cross-Sectional Studies', 'Drug Resistance, Bacterial', 'Enterobacteriaceae', 'Enterobacteriaceae Infections', 'Humans', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Microbial Sensitivity Tests', 'Neonatal Sepsis', 'Staphylococcal Infections', 'Staphylococcus', 'Strept... | 26,172,006 | [['N05.715.350.075', 'N06.850.490.250'], ['D27.505.954.122.085'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B03.440.450.425', 'B03.660.250.150'], ['C01.150.252.400.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Context-dependent seed dispersal by a scatter-hoarding corvid. | Corvids (crows, jays, magpies and nutcrackers) are important dispersers of large-seeded plants. Studies on captive or supplemented birds suggest that they flexibly adjust their scatter-hoarding behaviour to the context of social dynamics and relative seed availability. Because many corvid-dispersed trees show high annu... | ['Animals', 'Appetitive Behavior', 'Feeding Behavior', 'Passeriformes', 'Quercus', 'Seed Dispersal', 'Seeds', 'Territoriality'] | 26,876,417 | [['B01.050'], ['F01.145.113.111'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.248.620'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['G01.154.767', 'G15.620.500', 'G15.808'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['F01.145.875.864']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparative effects of various T cell subtypes on GVHD in a murine model for MHC-matched unrelated donor transplant. | Studies were undertaken to achieve a further understanding of T cell subtype involvement in minor-histocompatibility graft-versus-host disease (MiHL-GVHD) as it may occur in MHC-matched unrelated donor (MUD) transplantation. For this, the H-2 identical, but minor-histocompatibility disparate, B10.S----SJL/J mouse model... | ['Animals', 'Antigens, Differentiation', 'Antigens, Surface', 'Bone Marrow Transplantation', 'CD4-Positive T-Lymphocytes', 'CD5 Antigens', 'Female', 'Flow Cytometry', 'Graft vs Host Disease', 'Isoantibodies', 'Lymphocyte Depletion', 'Mice', 'Mice, Inbred Strains', 'Minor Histocompatibility Antigens', 'Spleen', 'T-Lymph... | 1,691,938 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['D23.050.301'], ['E02.095.147.725.040', 'E04.936.580.040'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D23.050.301.264.051.101', 'D23.050.301.264.894.101', 'D23.101.100.150.101', 'D23.101.100.894.101'], ['E01.37... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estrogen increases eNOS and NOx release in human coronary artery endothelium. | Estrogen protects against the development of coronary heart disease in women. This study was designed to examine the direct effects of estrogen on nitric oxide release and endothelial nitric oxide synthase (eNOS) expression in cultured human coronary artery endothelial cells (HCAECs). NOx (nitrate, nitrite, and nitric ... | ['Adenosine Triphosphate', 'Blotting, Western', 'Calcimycin', 'Calcium', 'Cells, Cultured', 'Coronary Vessels', 'Endothelium, Vascular', 'Estradiol', 'Estrogens', 'Fulvestrant', 'Humans', 'Male', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type III', 'Receptors, Estrogen', 'Up-Regulation'] | 10,942,167 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D03.633.100.221.173'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['A07.015.114.269', 'A07.015.908.194'], ['A07.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intraoperative radiotherapy (IORT) for surgically resected brain metastases: outcome analysis of an international cooperative study. | BACKGROUND AND OBJECTIVE: The ideal delivery of radiation to the surgical cavity of brain metastases (BMs) remains the subject of debate. Risks of local failure (LF) and radiation necrosis (RN) have prompted a reappraisal of the timing and/or modality of this critical component of BM management. IORT delivered at the t... | ['Aged', 'Brain Neoplasms', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Humans', 'Intraoperative Period', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Radiotherapy', 'Retrospective Studies', 'Treatment Outcome'] | 31,654,248 | [['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Activities of Linezolid against nontuberculous mycobacteria. | The activity of linezolid (Pfizer, USA) was tested by broth microdilution against 53 clinical isolates of non-tuberculous mycobacteria (NTM), including the common disease producing species Mycobacterium avium, M. intracellulare, M. fortuitum, M. chelonae and M. abscessus, obtained from western Turkey. The isolates of M... | ['Acetamides', 'Anti-Infective Agents', 'Endpoint Determination', 'Humans', 'Linezolid', 'Microbial Sensitivity Tests', 'Mycobacterium Infections, Nontuberculous', 'Nontuberculous Mycobacteria', 'Oxazolidinones', 'Species Specificity', 'Turkey'] | 18,080,676 | [['D02.065.064', 'D02.241.081.018.110'], ['D27.505.954.122'], ['E05.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.064.463', 'D02.241.081.018.110.525', 'D03.383.129.462.600.550'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['C01.150.252.410.040.552.475'], ['B03.510.024.962.500.720... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Urinary excretion of adrenal steroids, catecholamines and electrolytes in man, before and after acclimatization to cold in Antarctica. | 1. Urine samples were collected from four men before and during test cold exposures in Melbourne, Australia, and Mawson, Antarctica. Changes in the response of body temperature to the test exposures showed that the men had acclimatized to cold at Mawson.2. Excretion rates of 17-hydroxycorticosteroids and 17-ketosteroid... | ['17-Hydroxycorticosteroids', '17-Ketosteroids', 'Acclimatization', 'Adult', 'Antarctic Regions', 'Catecholamines', 'Cold Climate', 'Creatinine', 'Epinephrine', 'Humans', 'Male', 'Norepinephrine', 'Potassium', 'Sodium', 'Time Factors', 'Urine'] | 5,501,486 | [['D06.472.040.585.478'], ['D04.210.500.578.502', 'D06.472.040.502'], ['G07.025.133', 'G16.012.500.133'], ['M01.060.116'], ['Z01.158'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['G16.500.275.071.275', 'N06.230.300.100.250.275'], ['D03.383.129.308.207'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Production of L-asparaginase in Enterobacter aerogenes expressing Vitreoscilla hemoglobin for efficient oxygen uptake. | This study is the first utilizing Vitreoscilla hemoglobin in a heterologous bacterium, Enterobacter aerogenes, to determine the effect of such a highly efficient oxygen-uptake system on the production of l-asparaginase, an enzyme that has attracted considerable attention due to its anti-tumor activity. Here, we show th... | ['Aerobiosis', 'Ammonia', 'Anaerobiosis', 'Asparaginase', 'Bacterial Proteins', 'Cloning, Molecular', 'Enterobacter aerogenes', 'Enzyme Repression', 'Gene Expression', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Glucose', 'Hemoglobins', 'Hydrogen-Ion Concentration', 'Oxidation-Reduction', 'Oxygen Cons... | 14,593,509 | [['G02.111.017', 'G03.049'], ['D01.362.075', 'D01.625.050'], ['G02.111.062', 'G03.078'], ['D08.811.277.087.116'], ['D12.776.097'], ['E05.393.220'], ['B03.440.450.425.275.099', 'B03.660.250.150.170.049'], ['G05.308.320.300'], ['G05.297'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.3... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human hand transplantation: what have we learned? | Hand transplantation may become an important procedure for upper limb functional restoration. To date, 18 patients have been undergone 24 hand operations in the world. Initial results are extremely promising; the functional results are apparently superior to those obtained with prostheses. We report on the combined Fre... | ['Adolescent', 'Adult', 'Cadaver', 'Hand Transplantation', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Tissue Donors', 'Transplantation, Homologous', 'Treatment Outcome'] | 15,110,626 | [['M01.060.057'], ['M01.060.116'], ['C23.550.260.224'], ['E04.936.450.825.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['M01.898'], ['E04.936.864'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor. | Probably every cellular process is governed by protein-protein interaction (PPIs), which are often highly dynamic in nature being modulated by in- or external stimuli. Here we present KISS, for KInase Substrate Sensor, a mammalian two-hybrid approach designed to map intracellular PPIs and some of the dynamic features t... | ['Arrestins', 'Benchmarking', 'Biosensing Techniques', 'Endoplasmic Reticulum Stress', 'Endoribonucleases', 'Gene Expression Regulation', 'HEK293 Cells', 'Humans', 'Phosphorylation', 'Protein Interaction Mapping', 'Protein-Serine-Threonine Kinases', 'Receptor, Angiotensin, Type 1', 'Receptors, Somatostatin', 'STAT3 Tra... | 25,154,561 | [['D12.644.360.024.098', 'D12.776.157.057.005', 'D12.776.306.090', 'D12.776.476.024.104', 'D12.776.543.090'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['E05.601.043'], ['G04.434'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['G05.308'], ['A11.251.210.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
mtDNA variation in the Chibcha Amerindian Huetar from Costa Rica. | The genetic variation in a Chibcha-speaking Amerindian tribe from lower Central America, the Huetar, was analyzed using nucleotide sequences of the hypervariable segments of the mitochondrial DNA (mtDNA) control region, the frequencies of 10 Amerindian-specific mtDNA haplotypes, and the regional distribution of private... | ['Base Sequence', 'Costa Rica', 'DNA, Mitochondrial', 'Gene Deletion', 'Gene Frequency', 'Genetic Variation', 'Haplotypes', 'Humans', 'Indians, Central American', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Population Density'] | 7,835,876 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.107.169.238'], ['D13.444.308.283.225'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.330'], ['G05.365'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.575'], ['L01.453.245.667'], ['E05.393.620.500'], ['G05.365.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Genetics of the peloponnesean populations and the theory of extinction of the medieval peloponnesean Greeks. | Peloponnese has been one of the cradles of the Classical European civilization and an important contributor to the ancient European history. It has also been the subject of a controversy about the ancestry of its population. In a theory hotly debated by scholars for over 170 years, the German historian Jacob Philipp Fa... | ['Aged', 'Aged, 80 and over', 'DNA, Ancient', 'European Continental Ancestry Group', 'Genome, Human', 'Genotype', 'Greece', 'Human Migration', 'Humans', 'Models, Genetic', 'Pedigree'] | 28,272,534 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D13.444.308.065'], ['M01.686.508.400'], ['G05.360.340.350'], ['G05.380'], ['Z01.542.383'], ['I01.240.600.525', 'N01.224.625.525', 'N06.850.505.400.700.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['E05.393.673']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
5-Hydroxyeicosatetraenoic acid, leukotriene C4, and prostaglandin F2 alpha in amniotic fluid before and during term and preterm labor. | Arachidonic acid is metabolized by cyclooxygenase leading to prostaglandins and by lipoxygenases leading to hydroxyeicosatetraenoic acids (HETE) and leukotrienes (LT). Prostaglandins are potent uterine constrictors. 5-HETE and LTC4 also stimulate uterine contractions but their role in labor is not known. To estimate th... | ['Amniotic Fluid', 'Animals', 'Dinoprost', 'Female', 'Hydroxyeicosatetraenoic Acids', 'Labor, Obstetric', 'Macaca mulatta', 'Obstetric Labor, Premature', 'Osmolar Concentration', 'Pregnancy', 'SRS-A'] | 2,589,462 | [['A12.098', 'A16.378.149'], ['B01.050'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D10.251.355.255.100.300', 'D10.251.355.310.166.550'], ['G08.686.784.769.326'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['C13.703.420.491'], ['G02.640'], ['G08.686.784.769'], ['D10.251.355.255.100... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Muramidase and lactoferrin in adenoidal hypertrophies, hypertrophic and chronic infected tonsil tissue--a quantitative analysis]. | BACKGROUND: Muramidase and lactoferrin are important components of the antimicrobial defense system. Muramidase has the ability of opsonization and immunopotentiation and therefore a close relation to the lymphatic tissue. Till now there are only immunohistochemical and microbiological studies on the presence of murami... | ['Adenoids', 'Adolescent', 'Adult', 'Age Factors', 'Biofilms', 'Child', 'Child, Preschool', 'Chronic Disease', 'Data Interpretation, Statistical', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Hypertrophy', 'Lactoferrin', 'Middle Aged', 'Muramidase', 'Palatine Tonsil', 'Tonsillectomy', 'Tonsillitis'] | 16,142,620 | [['A04.623.557.500', 'A10.549.100', 'A14.724.557.500', 'A15.382.520.604.100'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['A20.593', 'G06.120'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.500'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300',... | ['Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Genetic evidence that multiple proteases are involved in modulation of heat-induced activation of the sigma factor SigI in Bacillus subtilis. | The Bacillus subtilis sigI-rsgI operon encodes the heat-inducible sigma factor SigI and its cognate anti-sigma factor RsgI. The heat-activated SigI positively regulates expression of sigI itself and genes involved in cell wall homeostasis and heat resistance. It remains unknown which protease(s) may contribute to degra... | ['Bacillus subtilis', 'Bacterial Proteins', 'Cell Wall', 'Down-Regulation', 'Gene Deletion', 'Gene Expression Regulation, Bacterial', 'Genetic Complementation Test', 'Heat-Shock Response', 'Hot Temperature', 'Peptide Hydrolases', 'Promoter Regions, Genetic', 'Sigma Factor', 'Transcription, Genetic'] | 28,333,276 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['A11.284.183'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308.300'], ['E05.393.281.526'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The direct release of nitric oxide by gypenosides derived from the herb Gynostemma pentaphyllum. | Herbal medicines are increasingly being utilized to treat a wide variety of disease processes. Gypenosides are triterpenoid saponins contained in an extract from Gynostemma pentaphyllum and are reported to be effective in the treatment of cardiovascular diseases; however, the mechanism underlying the therapeutic effect... | ['Animals', 'Aorta', 'Cattle', 'Cells, Cultured', 'Coronary Vessels', 'Drugs, Chinese Herbal', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'In Vitro Techniques', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Plant Extracts', 'Saponins', 'Swine', 'Terpenes', 'Vasodilation'] | 10,534,439 | [['B01.050'], ['A07.015.114.056'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['A07.015.114.269', 'A07.015.908.194'], ['D20.215.784.500.350', 'D26.335'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.389'], ['E05.481'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['D01.339.387', 'D01.625.550.500'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Small circular DNAs for synthesis of the human telomere repeat: varied sizes, structures and telomere-encoding activities. | We describe the construction, structural properties and enzymatic substrate abilities of a series of circular DNA oligonucleotides that are entirely composed of the C-rich human telomere repeat, (CCCTAA)n. The nanometer-sized circles range in length from 36 to 60 nt, and act as templates for synthesis of human telomere... | ['DNA, Circular', 'DNA-Directed DNA Polymerase', 'Humans', 'Repetitive Sequences, Nucleic Acid', 'Telomere'] | 15,520,461 | [['D13.444.308.283', 'G02.111.570.820.486.212', 'G05.360.580.156'], ['D08.811.913.696.445.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.708', 'G05.360.080.708'], ['A11.284.430.106.279.345.190.160.845', 'G05.360.160.845']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reproductive behaviour in the male cricket Gryllus bimaculatus DeGeer. I. Structure and function of the genitalia. | We have investigated the morphology and physiology of the genitalia of the male cricket to establish a basis for neuroethological study of its reproductive behaviour. First, the structure of the phallic complex, including the dorsal pouch, guiding rod, epiphallus, ventral lobes and median pouch, are described, as are t... | ['Animals', 'Behavior, Animal', 'Biomechanical Phenomena', 'Copulation', 'Genitalia, Male', 'Gryllidae', 'Male', 'Reproduction', 'Sexual Behavior, Animal'] | 11,222,129 | [['B01.050'], ['F01.145.113'], ['G01.154.090', 'G01.374.089'], ['F01.145.113.252.748.200'], ['A05.360.444'], ['B01.050.500.131.617.678.410'], ['G08.686.784'], ['F01.145.113.252.748']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53. | As a deubiquitinating enzyme (DUB), the physiological substrates of ataxin-3 (ATX-3) remain elusive, which limits our understanding of its normal cellular function and that of pathogenic mechanism of spinocerebellar ataxia type 3 (SCA3). Here, we identify p53 to be a novel substrate of ATX-3. ATX-3 binds to native and ... | ['Animals', 'Apoptosis', 'Ataxin-3', 'Machado-Joseph Disease', 'Mice', 'Protein Stability', 'Tumor Suppressor Protein p53'] | 27,851,749 | [['B01.050'], ['G04.146.954.035'], ['D08.811.037.250', 'D12.776.631.069.875', 'D12.776.660.075.875'], ['C10.228.140.252.190.530.530', 'C10.228.140.252.700.700.500', 'C10.228.854.787.875.500', 'C10.574.500.825.700.500', 'C10.597.350.090.500.530.530', 'C16.320.400.780.875.500'], ['B01.050.150.900.649.313.992.635.505.500'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hyperpolarizing and depolarizing GABAA receptor-mediated dendritic inhibition in area CA1 of the rat hippocampus. | 1. gamma-Aminobutyric acidA (GABAA) receptor-mediated inhibition of pyramidal neuron dendrites was studied in area CA1 of the rat hippocampal slice preparation with the use of intracellular and extracellular recording and one-dimensional current source-density (CSD) analysis. 2. Electrical stimulation of Schaffer colla... | ['2-Amino-5-phosphonovalerate', 'Animals', 'Bicuculline', 'Chlorides', 'Dendrites', 'Evoked Potentials', 'GABA-A Receptor Antagonists', 'Hippocampus', 'In Vitro Techniques', 'Kinetics', 'Mathematics', 'Membrane Potentials', 'Models, Neurological', 'Neurons', 'Organophosphorus Compounds', 'Pyramidal Tracts', 'Quinoxalin... | 1,684,989 | [['D12.125.070.950.100', 'D12.125.740.025'], ['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['D01.210.450.150', 'D01.248.497.158.215'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['G07.265.216.500', 'G11.561.200.500'], ['D27.505.519.625.240.300.500', 'D27.505.696.577.240.300.500'], ['A08.186.211.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnesium lithospermate B improves the gut microbiome and bile acid metabolic profiles in a mouse model of diabetic nephropathy. | Magnesium lithospermate B (MLB) is a new drug marketed in China to treat angina, but its low oral bioavailability limits its clinical application to the intravenous route. Paradoxically, orally administered low-dose MLB was found to alleviate kidney injury in diabetic nephropathy (DN) rats, but its mechanism of action ... | ['Animals', 'Bile Acids and Salts', 'Computational Biology', 'Diabetic Nephropathies', 'Disease Models, Animal', 'Drugs, Chinese Herbal', 'Gastrointestinal Microbiome', 'Kidney Function Tests', 'Male', 'Mice', 'Mice, Inbred DBA'] | 29,941,869 | [['B01.050'], ['D04.210.500.105'], ['H01.158.273.180', 'L01.313.124'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D20.215.784.500.350', 'D26.335'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['E01.370.390.400'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Surgery of Morton's neuroma: dorsal or plantar approach? | In this prospective study, 52 patients with 55 neuromas were studied in two groups. 26 patients underwent excision of the neuroma through a plantar approach and 26 through a dorsal approach. Average follow-up was 3.1 years after excision. Histology confirmed a neuroma in 51 cases. Results show that in the dorsal group ... | ['Cicatrix', 'Female', 'Follow-Up Studies', 'Foot', 'Foot Diseases', 'Humans', 'Length of Stay', 'Male', 'Metatarsal Bones', 'Middle Aged', 'Nerve Compression Syndromes', 'Neuroma', 'Pain, Postoperative', 'Patient Satisfaction', 'Prospective Studies', 'Weight-Bearing', 'Work'] | 9,046,143 | [['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A01.378.610.250'], ['C05.360', 'C17.800.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['A02.835.232.043.300.492']... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Haemodynamic performance of neuromuscular electrical stimulation (NMES) during recovery from total hip arthroplasty. | BACKGROUND: Patients post total hip arthroplasty (THA) remain at high risk of developing Deep Vein Thrombosis (DVT) during the recovery period following surgery despite the availability of effective pharmacological and mechanical prophylactic methods. The use of calf muscle neuromuscular electrical stimulation (NMES) d... | ['Aged', 'Arthroplasty, Replacement, Hip', 'Blood Flow Velocity', 'Electric Stimulation Therapy', 'Female', 'Hemodynamics', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Muscle Contraction', 'Muscle, Skeletal', 'Pain', 'Pain Measurement', 'Patient Satisfaction', 'Popliteal Vein', 'Postoperative Care', 'Postoperative Complic... | 23,497,524 | [['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['G11.427.494'], ['A02.633.567',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells. | The promyelocytic leukemia (HL60) cell line differentiates into monocyte-like cells after treatment with phorbol dibutyrate (PBt2). In contrast, bryostatin 1 (bryo), a structurally distinct protein kinase C (PKC) activator, does not induce differentiation and blocks the cytostatic effect of PBt2. The divergent response... | ['Amino Acid Sequence', 'Antibodies', 'Cell Line', 'Cell Nucleus', 'Humans', 'Isoenzymes', 'Kinetics', 'Lamin Type B', 'Lamins', 'Leukemia, Promyelocytic, Acute', 'Molecular Sequence Data', 'Nuclear Envelope', 'Nuclear Proteins', 'Peptides', 'Phosphorylation', 'Protamine Kinase', 'Protein Kinase C'] | 1,845,965 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['D12.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Frequency of posterior vitreous detachment as determined intraoperatively in patients with an idiopathic epiretinal membrane]. | INTRODUCTION: The prevalence of a posterior vitreous detachment in patients with an idiopathic epiretinal membrane is often exaggerated in the literature. This may make the surgeon become overconfident during vitrectomy.PATIENTS AND METHODS: 34 patients with an idiopathic epiretinal membrane (mean age 72.9 years) were ... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Epiretinal Membrane', 'Female', 'Follow-Up Studies', 'Humans', 'Intraoperative Complications', 'Male', 'Middle Aged', 'Visual Acuity', 'Vitrectomy', 'Vitreous Detachment'] | 20,155,657 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C11.768.328'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ADP-ribosylation of nonmuscle actin with component I of C2 toxin. | C2 toxin elaborated by Clostridium botulinum type C is composed of two dissimilar protein components, designated components I and II. Component I of the toxin caused ADP-ribosylation of a protein of Mr 45,000 in chicken tissue homogenates and also purified nonmuscle but not muscle actin. The endogenous ADP-ribosylation... | ['Actins', 'Adenosine Diphosphate Ribose', 'Animals', 'Botulinum Toxins', 'Brain Chemistry', 'Cell Line', 'Chickens', 'Clostridium botulinum', 'Intestines', 'Kidney', 'Macaca fascicularis', 'Molecular Weight', 'Muscles', 'NAD', 'Nucleoside Diphosphate Sugars', 'Rabbits'] | 3,518,719 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.633.100.759.646.138.124.070.125', 'D09.408.620.569.070.125', 'D13.695.667.138.124.070.125', 'D13.695.827.068.124.070.125', 'D13.695.827.708.070.125'], ['B01.050'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.15... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of neural stem cells on apoptosis of PC12 cells induced by serum deprivation. | Neural stem cells (NSCs) have a bright application prospect to be used to treat neurodegenerative diseases due to their capacity to give rise to the appropriate cell types when they are grafted. At present, however, the function of NSCs after transplantation is not quite ensured, whether to replace the degenerative cel... | ['Animals', 'Apoptosis', 'Cell Differentiation', 'Cell Survival', 'Cells, Cultured', 'Coculture Techniques', 'Culture Media', 'Culture Media, Serum-Free', 'Dopamine', 'Neurons', 'PC12 Cells', 'Rats', 'Stem Cells', 'Time Factors'] | 17,585,776 | [['B01.050'], ['G04.146.954.035'], ['G04.152'], ['G04.346'], ['A11.251'], ['E05.481.500.374'], ['D27.720.470.305', 'E07.206'], ['D27.720.470.305.255', 'E07.206.255'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['A08.675', 'A11.671'], ['A11.251.210.190.750', 'A11.251.860.180.750',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple E2F-induced microRNAs prevent replicative stress in response to mitogenic signaling. | Transcription of microRNAs (miRNAs) is thought to be regulated similarly to that of protein-coding genes. However, how miRNAs are regulated during the cell division cycle is not well understood. We have analyzed the transcription profiles of miRNAs in response to mitogenic stimulation in primary fibroblasts. About 33% ... | ['Animals', 'Binding Sites', 'Cell Cycle Proteins', 'Chromatin Immunoprecipitation', 'DNA Damage', 'DNA Replication', 'E2F Transcription Factors', 'E2F1 Transcription Factor', 'E2F2 Transcription Factor', 'E2F3 Transcription Factor', 'Fibroblasts', 'G1 Phase', 'Gene Expression Profiling', 'Gene Expression Regulation', ... | 20,404,092 | [['B01.050'], ['G02.111.570.120'], ['D12.776.167'], ['E05.393.170', 'E05.478.605.160'], ['G05.200'], ['G02.111.225', 'G05.226'], ['D12.776.930.211'], ['D12.644.360.024.328.049', 'D12.776.157.057.158.049', 'D12.776.476.024.420.049', 'D12.776.660.769.049', 'D12.776.930.211.500'], ['D12.776.930.211.625'], ['D12.776.930.21... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular characterization of folate receptor 1 mutations delineates cerebral folate transport deficiency. | Cerebral folate transport deficiency is an inherited brain-specific folate transport defect that is caused by mutations in the folate receptor 1 gene coding for folate receptor alpha (FRá). This genetic defect gives rise to a progressive neurological disorder with late infantile onset. We screened 72 children with low ... | ['Adolescent', 'Alleles', 'Animals', 'CHO Cells', 'Child', 'Child, Preschool', 'Cricetinae', 'Female', 'Fibroblasts', 'Folate Receptor 1', 'Folic Acid', 'Folic Acid Deficiency', 'Hep G2 Cells', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Mutation', 'Phenotype', 'Protein Transport', 'Tetrahydrofolates'] | 22,586,289 | [['M01.060.057'], ['G05.360.340.024.340.030'], ['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.992.635.075.250'], ['A11.329.228'], ['D12.776.157.530.450.074.500.299.500.500', 'D12.776.395.550.448.370.500', 'D12.776.543.484.500.370.500', 'D12.776.543.550.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Preheparin lipoprotein lipase mass and apolipoproteinC-III ratio helps identify postprandial triglyceride metabolic marker]. | Serum lipid profiles have usually been evaluated using blood specimen in fasting state. However, postprandial hypertriglyceridemia is important risk factor for atherosclerosis. In the present study, we determined several parameters of triglyceride (TG) metabolism in healthy volunteers. Serum concentrations of TG in fas... | ['Adult', 'Apolipoprotein C-III', 'Biomarkers', 'Fasting', 'Heparin', 'Humans', 'Hypertriglyceridemia', 'Lipoprotein Lipase', 'Male', 'Middle Aged', 'Postprandial Period', 'Triglycerides', 'Ultracentrifugation'] | 18,154,034 | [['M01.060.116'], ['D10.532.091.400.875', 'D12.776.070.400.400.875', 'D12.776.521.120.400.875'], ['D23.101'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.851'], ['D08.811.277.352.100.430'], ['M01.060.116.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A cytologic, ultrastructural and immunocytochemical comparison of tumor cells and cell cultures originating in invasive bladder carcinoma. | Tumor cells and urine-voided cells from patients with invasive bladder carcinoma as well as from healthy patients were examined cytologically, ultrastructurally and immunocytochemically. The ultrastructure of tumor cells showed an abundant, dilated, rough endoplasmic reticulum in the form of membrane-bound vacuoles ful... | ['Carcinoma, Transitional Cell', 'Endoplasmic Reticulum', 'Glycosaminoglycans', 'Humans', 'Immunoenzyme Techniques', 'Inclusion Bodies', 'Microscopy, Electron', 'Neoplasm Invasiveness', 'Staining and Labeling', 'Urinary Bladder', 'Urinary Bladder Neoplasms', 'Urine'] | 1,379,923 | [['C04.557.470.200.430'], ['A11.284.430.214.190.875.248'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A11.284.420'], ['E01.370.350.515.402', 'E05.595.402'], ['C04.697.645', 'C23.550.727.645'], ['E01.370.225.500.620.670', 'E01.370.225.75... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and evaluation of hexahydropyrrolo[3,4-d]isoxazole-4,6-diones as anti-stress agents. | A series of 2,3-diphenyl-5-(naphthalen-1-yl)-4H-2,3,3a,5,6,6a-hexahydropyrrolo[3,4-d]isoxazole-4,6-dione derivatives were synthesized via 1,3-dipolar cycloaddition of azomethine N-oxides with N-(á-naphthyl)maleimide. The pyrrolo-isoxazole derivatives were assigned cis- and trans- configurations (3-A and 3-B) with respe... | ['Animals', 'Anti-Anxiety Agents', 'Behavior, Animal', 'Immobilization', 'Isoxazoles', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Mice', 'Molecular Structure', 'Pyrroles', 'Spectroscopy, Fourier Transform Infrared', 'Stress, Physiological'] | 22,178,092 | [['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['F01.145.113'], ['E05.472'], ['D03.383.129.385'], ['E05.196.867.519'], ['E05.196.566'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.111.570', 'G02.466'], ['D03.383.129.578'], ['E05.196.712.726.676.700', 'E05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment-related reductions in PTSD and changes in physical health symptoms in women. | This study examined the relationship between change in posttraumatic stress disorder (PTSD) symptoms over the course of PTSD treatment and the association with changes in general physical health symptoms. Both positive health habits (e.g., exercise) and negative (e.g., smoking), were examined to determine if they accou... | ['Adult', 'Cognitive Behavioral Therapy', 'Female', 'Habits', 'Health Behavior', 'Health Status', 'Humans', 'Middle Aged', 'Stress Disorders, Post-Traumatic', 'Treatment Outcome'] | 23,471,544 | [['M01.060.116'], ['F04.754.137.350'], ['F01.145.466'], ['F01.145.488'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.950.750.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. | Several experimental and clinical studies have shown that oxidized low-density lipoprotein and oxidation-sensitive mechanisms are central in the pathogenesis of vascular dysfunction and atherogenesis. Here, we have used p66(Shc-/-) and WT mice to investigate the effects of high-fat diet on both systemic and tissue oxid... | ['Adaptor Proteins, Signal Transducing', 'Adaptor Proteins, Vesicular Transport', 'Animals', 'Apoptosis', 'Arteriosclerosis', 'Dietary Fats', 'Endothelium, Vascular', 'Gene Deletion', 'Immunohistochemistry', 'Lipids', 'Longevity', 'Male', 'Mice', 'Mice, Knockout', 'Oxidative Stress', 'Proteins', 'Shc Signaling Adaptor ... | 12,571,362 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.543.990.150'], ['B01.050'], ['G04.146.954.035'], ['C14.907.137.126'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['A07.015.700.500', 'A10.272.491.355'], ['G05.365.590.762.320', 'G05.558.800.320'], ['E01.370.225.500.607.512', 'E01.370.225.750.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Influence of aspirin formulation and dose on concentration of total salicylate in rat kidney. | Rats received the equivalent of 100, 250, 500, or 700 mg/kg of 14C-aspirin orally as a suspension or as a solution of a buffered, effervescent, aspirin-containing product. Animals in each dose group were sacrificed at time intervals ranging from 0.5 to 24 hr after dosing. The 14C content of whole blood, plasma, and hom... | ['Animals', 'Aspirin', 'Buffers', 'Kidney', 'Male', 'Rats', 'Rats, Inbred Strains', 'Salicylates', 'Time Factors'] | 1,263,101 | [['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['D27.720.470.280'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D02.241.223.100.300.595', 'D02.241.511.390.595', 'D02.455.426.559.389.127.281.595', 'D02.455.426.559.389... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reductive dechlorination of weathered Aroclor 1260 during anaerobic biotreatment of Arctic soils. | We investigated the microbial reductive dechlorination of both weathered (aged) and nonweathered (freshly added) Aroclor 1260 in aerobic soil from Resolution Island, Nunavut, Canada. Initial polychlorinated biphenyl (PCB) concentrations were 106 and 100 ppm, respectively. The aerobic soil samples were inoculated with a... | ['Arctic Regions', 'Aroclors', 'Bacteria, Aerobic', 'Biodegradation, Environmental', 'Chlorine', 'Environmental Pollutants', 'Polychlorinated Biphenyls', 'Soil Pollutants'] | 12,674,343 | [['Z01.208'], ['D02.309.750.500', 'D02.455.526.439.773.292', 'D02.455.526.439.785.292'], ['B03.120'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.380.150', 'D01.362.225'], ['D27.888.284'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['D27.888.284.756']] | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Influence of aminoglycoside usage on susceptibilities. | Units of aminoglycosides issued from the hospital pharmacy and susceptibilities for Serratia marcescens and Pseudomonas aeruginosa were retrospectively analyzed for the years 1975-82. The use of gentamicin appears to select out for tobramycin-resistant S. marcescens and gentamicin-, tobramycin-susceptible P. aeruginosa... | ['Drug Resistance, Microbial', 'Drug Utilization', 'Gentamicins', 'Pseudomonas aeruginosa', 'Serratia marcescens', 'Tobramycin'] | 3,922,684 | [['G06.225', 'G07.690.773.984.269'], ['N04.452.706.477'], ['D09.408.051.374'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['B03.440.450.425.814.664', 'B03.660.250.150.720.500'], ['D09.408.051.476.600.800']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Expression of Spy1 protein in human non-Hodgkin's lymphomas is correlated with phosphorylation of p27 Kip1 on Thr187 and cell proliferation. | Aberrations in cell cycle control are often observed in tumors and might even be necessary in tumor development. Spy1, a novel cell cycle regulatory protein, can control cell progression and survival through the atypical activation of cyclin-dependent kinases (CDKs). In this progression, the phosphorylation of p27(Kip1... | ['Cell Cycle Proteins', 'Cell Proliferation', 'Cyclin-Dependent Kinase Inhibitor p27', 'Humans', 'Immunoblotting', 'Immunohistochemistry', 'Immunoprecipitation', 'Jurkat Cells', 'Ki-67 Antigen', 'Lymphoma, Non-Hodgkin', 'Phosphorylation', 'Prognosis', 'Transfection'] | 22,492,278 | [['D12.776.167'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.360.225.600', 'D12.776.167.187.600', 'D12.776.476.225.600', 'D12.776.624.776.355.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Total body calcium measurements using neutron-activation analysis in Cushing's syndrome. | Total body calcium content (TBCa) was estimated by in vivo neutron activation analysis in 16 patients (14 female, 2 male) with active Cushing's syndrome, pituitary driven in all but two cases. Apart from being nonreproductive, patients were unselected. TBCa was below the predicted young normal value in all patients (me... | ['Adrenalectomy', 'Adult', 'Aged', 'Brachytherapy', 'Calcium', 'Cushing Syndrome', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Neutron Activation Analysis', 'Thyroxine'] | 3,093,025 | [['E04.270.115'], ['M01.060.116'], ['M01.060.116.100'], ['E02.815.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C19.053.800.367'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['M01.060.116.630'], ['E05.196.039.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuropsychological correlates of positive vs. negative schizophrenic symptomatology. | This study attempts to further the validity of the subtype hypothesis in schizophrenia by testing the relationship of neuropsychological functions in schizophrenics with predominantly positive vs. negative symptoms. The Brief Psychiatric Rating Scale (BPRS) was used to parse schizophrenics into positive and negative sy... | ['Adult', 'Attention', 'Depression', 'Female', 'Frontal Lobe', 'Humans', 'Male', 'Mental Recall', 'Neuropsychological Tests', 'Psychiatric Status Rating Scales', 'Psychomotor Performance', 'Schizophrenia', 'Schizophrenic Psychology', 'Wechsler Scales'] | 9,516,663 | [['M01.060.116'], ['F02.830.104.214'], ['F01.145.126.350'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F04.711.513'], ['F04.711.513.653'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F03.700.750'], ['F04.824'], ['F04.711.141.493.822']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pesticide exposure in honey bees results in increased levels of the gut pathogen Nosema. | Global pollinator declines have been attributed to habitat destruction, pesticide use, and climate change or some combination of these factors, and managed honey bees, Apis mellifera, are part of worldwide pollinator declines. Here we exposed honey bee colonies during three brood generations to sub-lethal doses of a wi... | ['Animals', 'Bees', 'Colony Count, Microbial', 'Imidazoles', 'Neonicotinoids', 'Nitro Compounds', 'Nosema', 'Pesticides'] | 22,246,149 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D03.383.129.308'], ['D03.383.464'], ['D02.640'], ['B01.300.360.500.500.100.400'], ['D27.720.031.700', 'D27.888.723']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A pilot trial to assess potential effects of selective intracoronary bone marrow-derived progenitor cell infusion in patients with nonischemic dilated cardiomyopathy: final 1-year results of the transplantation of progenitor cells and functional regeneration enhancement pilot trial in patients with nonischemic dilated ... | BACKGROUND: Intracoronary administration of bone marrow-derived progenitor cells (BMC) was shown to improve coronary microvascular function in ischemic heart disease. Because coronary microvascular dysfunction is implicated in the pathogenesis and prognosis of nonischemic dilated cardiomyopathy (DCM), we investigated t... | ['Aged', 'Biomarkers', 'Bone Marrow Transplantation', 'Cardiac Catheterization', 'Cardiomyopathy, Dilated', 'Catheterization', 'Cell Proliferation', 'Coronary Circulation', 'Echocardiography, Doppler', 'Female', 'Humans', 'Male', 'Microcirculation', 'Middle Aged', 'Myocardial Contraction', 'Myocardium', 'Natriuretic Pe... | 19,808,371 | [['M01.060.116.100'], ['D23.101'], ['E02.095.147.725.040', 'E04.936.580.040'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['E02.148', 'E05.157'], ['G04.161.750', 'G07.345.249.410.750'], ['G09.330.100.324'], ['E01.370.350.130.750.220', 'E01.370.350.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bibliography. Current world literature. | This bibliography is compiled by clinicians from the journals listed at the end of this publication. It is based on literature entered into our database between 1 March 2008 and 28 February 2009 (articles are generally added to the database about two and a half months after publication). In addition, the bibliography c... | ['Animals', 'Disease Models, Animal', 'Humans', 'Lung Neoplasms', 'Neoplasm Staging', 'Pleural Diseases'] | 19,494,724 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E01.789.625'], ['C08.528']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peripheral Vestibular and Balance Function in Athletes With and Without Concussion. | BACKGROUND AND PURPOSE: According to the most recent consensus statement on management of sport-related concussion (SRC), athletes with suspected SRC should receive a comprehensive neurological examination. However, which measures to include in such an examination are not defined. Our objectives were to (1) evaluate te... | ['Adult', 'Athletic Injuries', 'Brain Concussion', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Neurologic Examination', 'Postural Balance', 'Reflex, Vestibulo-Ocular', 'Reproducibility of Results', 'Vestibule, Labyrinth', 'Young Adult'] | 31,205,229 | [['M01.060.116'], ['C26.115'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.376... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells. | Epidoxorubicin and daunorubicin are proposed to be cytotoxic to tumor cells by catalyzing production of formaldehyde through redox cycling and using the formaldehyde for covalent attachment to DNA at G bases. The crystal structure of epidoxorubicin covalently bound to a d(CGCGCG) oligomer was determined to 1.6 A resolu... | ['Antineoplastic Agents', 'Breast Neoplasms', 'Cross-Linking Reagents', 'Crystallography, X-Ray', 'DNA Adducts', 'DNA, Neoplasm', 'Daunorubicin', 'Epirubicin', 'Humans', 'Intercalating Agents', 'Nucleic Acid Conformation', 'Oligonucleotides', 'Tissue Distribution', 'Tumor Cells, Cultured'] | 10,489,446 | [['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['D27.720.470.410.210'], ['E05.196.309.742.225'], ['D13.444.308.135', 'G05.200.104'], ['D13.444.308.425'], ['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200', 'D09.408.051.059.200'], ['D02.455.426.559.847.562.050.200.175.200', 'D04.615.562.050.200.175.200... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental exposure to bacteria and viruses may provide oncolytic protection against cancers, and declining exposure to infections may contribute to a rising incidence of cancer. | Over the past century, the incidence of cancer rose markedly in developed countries. Many underlying factors are known, but not all of them. Over the same century, advances in public health and hygiene practically eradicated many infectious illnesses, and exposure to some untargeted infectious agents has also declined.... | ['Bacterial Infections', 'Environmental Exposure', 'Humans', 'Incidence', 'Neoplasms', 'Virus Diseases'] | 17,030,097 | [['C01.150.252'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04'], ['C01.925']] | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association. | We report an interesting association of inflammatory myopathy, characterized pathologically as dermatomyositis, with bronchiolitis obliterans/organizing pneumonia and anti-histidyl-tRNA synthetase (Jo-1) antibody. The relations of different types of pulmonary involvement to inflammatory myopathy and antisynthetase anti... | ['Autoantibodies', 'Cryptogenic Organizing Pneumonia', 'Dermatomyositis', 'Glucocorticoids', 'Histidine-tRNA Ligase', 'Humans', 'Male', 'Middle Aged', 'Prednisone'] | 9,067,664 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C08.127.446.135.140.200', 'C08.381.483.487.249', 'C08.381.495.146.135.140.200', 'C08.381.765.500.750.249'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['D06.472.040.543', 'D27.505.696... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Atrophy of corrugator supercilii muscle in a patient induced by the onabotulinum toxin injection. | Onabotulinum toxin has been used to treat a variety of headaches. We report a case of a 29-year-old woman who developed temporary and reversible atrophy of corrugator supercilii muscle after onabotulinum toxin (Botox, Allergan, Irvine, CA, USA) injection. To our best knowledge this has not been described in the literat... | ['Adult', 'Atrophy', 'Botulinum Toxins, Type A', 'Facial Muscles', 'Female', 'Headache', 'Humans', 'Neuromuscular Agents', 'Pain Measurement'] | 22,085,341 | [['M01.060.116'], ['C23.300.070'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['A02.633.567.400', 'A14.363'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.663.700'], ['E01.370.600.550.324']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Performance of MTBDR plus for detecting high/low levels of Mycobacterium tuberculosis resistance to isoniazid. | SETTING: We recently evaluated the Genotype MTBDR test for assessing Mycobacterium tuberculosis resistance to rifampicin (RMP) and isoniazid (INH) by detecting mutations in rpoB (codons 511-533) and katG (codon 315). A new version of the test, MTBDR plus, has been designed to also detect mutations in the regulatory reg... | ['Antitubercular Agents', 'Bacterial Proteins', 'Biological Assay', 'DNA-Directed RNA Polymerases', 'Drug Resistance, Bacterial', 'Humans', 'Isoniazid', 'Mutation', 'Mycobacterium tuberculosis', 'Predictive Value of Tests', 'Reproducibility of Results', 'Rifampin'] | 19,146,757 | [['D27.505.954.122.085.255'], ['D12.776.097'], ['E05.091'], ['D08.811.913.696.445.735.270'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['G05.365.590'], ['B03.510.024.962.500.702', 'B03.510.460.40... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Health maintenance organizations, health care reform, and persons with serious mental illness. | Implementation of the Clinton Administration's proposed Health Security Act could significantly increase the number of seriously mentally ill persons enrolled in health maintenance organizations (HMOs). Studies of the mental health status and outcomes of seriously mentally ill persons treated in HMOs show conflicting f... | ['Health Care Reform', 'Health Services Accessibility', 'Humans', 'Managed Care Programs', 'Medicaid', 'Mental Disorders', 'United States'] | 7,989,021 | [['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N03.219.521.346.506.564.655', 'N03.706.615.693']... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Collateral projections of neurons of the rat globus pallidus to the striatum and substantia nigra. | Double retrograde fluorescent tracing techniques were used to evaluate the possibility that ascending and descending projections from the globus pallidus arise from divergent axon collaterals. Appropriately placed injections of different tracers (True Blue, Nuclear Yellow) into the substantia nigra and the striatum res... | ['Animals', 'Corpus Striatum', 'Globus Pallidus', 'Male', 'Neural Pathways', 'Rats', 'Substantia Nigra'] | 6,479,259 | [['B01.050'], ['A08.186.211.200.885.287.249.487'], ['A08.186.211.200.885.287.249.487.397'], ['A08.612'], ['B01.050.150.900.649.313.992.635.505.700'], ['A08.186.211.132.659.413.656']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Island method for estimating the statistical significance of profile-profile alignment scores. | BACKGROUND: In the last decade, a significant improvement in detecting remote similarity between protein sequences has been made by utilizing alignment profiles in place of amino-acid strings. Unfortunately, no analytical theory is available for estimating the significance of a gapped alignment of two profiles. Many ex... | ['Computational Biology', 'Models, Statistical', 'Proteins', 'Sequence Alignment', 'Sequence Analysis, Protein'] | 19,379,500 | [['H01.158.273.180', 'L01.313.124'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['D12.776'], ['E05.393.751'], ['E05.393.760.705']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
The effect of perindopril on cardiovascular morbidity and mortality in patients with diabetes in the EUROPA study: results from the PERSUADE substudy. | AIMS: The aim of this study was to assess the effect of the angiotensin converting enzyme inhibitor perindopril on cardiovascular events in diabetic patients with coronary artery disease.METHODS AND RESULTS: A total of 1502 diabetic patients with known coronary artery disease and without heart failure of 12 218 overall... | ['Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Coronary Artery Disease', 'Death, Sudden, Cardiac', 'Diabetic Angiopathies', 'Double-Blind Method', 'Female', 'Heart Arrest', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Perindopril', 'Prospective Studies'] | 15,860,521 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.383.220', 'C23.550.260.322.250'], ['C14.907.320', 'C19.246.099.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C14.280.383']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incidence of Chlamydia trachomatis in peripartum fallopian tubes. | We investigated the presence of Chlamydia trachomatis in fallopian tubes of patients undergoing Pomeroy tubal ligation in the immediate postpartum period with culture on cycloheximide-pretreated McCoy cells and with immunofluorescence staining. Two of 20 women were culture positive in both tubes, representing 10% cultu... | ['Adult', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Fallopian Tubes', 'Female', 'Humans', 'Postpartum Period', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Pregnancy Outcome'] | 3,351,818 | [['M01.060.116'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.190.750'], ['A05.360.319.114.373', 'A13.706.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.702'], ['G08.686.784.769'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bariatric Embolization: Pilot Study on the Impact of Gastroprotective Agents and Arterial Distribution on Ulceration Risk and Efficacy in a Porcine Model. | PURPOSE: To assess whether the number of fundal arteries embolized and use of gastroprotective agents have an impact on ghrelin suppression and gastric ulceration rates.MATERIALS AND METHODS: Twenty-two healthy, growing swine (mean, 38.4 kg; range, 30.3-47.0 kg) were evaluated. Six control swine underwent a sham proced... | ['Angiography', 'Animals', 'Anti-Ulcer Agents', 'Arteries', 'Biomarkers', 'Cytoprotection', 'Down-Regulation', 'Embolization, Therapeutic', 'Gastric Fundus', 'Gastric Mucosa', 'Ghrelin', 'Models, Animal', 'Omeprazole', 'Pilot Projects', 'Proton Pump Inhibitors', 'Stomach Ulcer', 'Sucralfate', 'Sus scrofa'] | 27,717,647 | [['E01.370.350.700.060', 'E01.370.370.050'], ['B01.050'], ['D27.505.954.483.203'], ['A07.015.114'], ['D23.101'], ['G07.690.773.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E02.520.360', 'E02.926.500'], ['A03.556.875.875.419'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.699.301', 'D12.644.548.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Retained transcranial knife blade with transection of the internal carotid artery treated by staged endovascular and surgical therapy: technical case report. | BACKGROUND AND IMPORTANCE: We describe the use of proximal and distal endovascular coil embolization of the internal carotid artery followed by operative removal of a retained foreign object transecting the petrocavernous portion of the internal carotid artery.CLINICAL PRESENTATION: A 20-year-old man sustained a stab w... | ['Carotid Artery Injuries', 'Cerebral Angiography', 'Embolization, Therapeutic', 'Foreign Bodies', 'Humans', 'Male', 'Temporal Bone', 'Tomography, X-Ray Computed', 'Wounds, Stab', 'Young Adult'] | 25,714,518 | [['C10.228.140.300.200.345', 'C10.228.140.300.350.500', 'C10.900.250.300', 'C14.907.253.123.345', 'C14.907.253.535.500', 'C26.915.200.200'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['E02.520.360', 'E02.926.50... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
How epicardial electrodes influence the transmembrane potential during a strong shock. | This paper analyzes a possible artifact that may corrupt experiments studying defibrillation of the heart. Our hypothesis is that surface recording electrodes can influence the transmembrane potential during a shock. In the vicinity of an electrode, current leaves the intracellular space to take advantage of the low re... | ['Artifacts', 'Electric Stimulation', 'Electrocardiography', 'Electrodes', 'Membrane Potentials', 'Models, Cardiovascular', 'Pericardium'] | 11,791,674 | [['E05.047'], ['E05.723.402'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E07.305.250'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E05.599.395.161'], ['A07.541.795', 'A10.615.789.470']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Artificial neural network model of the relationship between Betula pollen and meteorological factors in Szczecin (Poland). | Birch pollen is one of the main causes of allergy during spring and early summer in northern and central Europe. The aim of this study was to create a forecast model that can accurately predict daily average concentrations of Betula sp. pollen grains in the atmosphere of Szczecin, Poland. In order to achieve this, a no... | ['Allergens', 'Betula', 'Forecasting', 'Neural Networks, Computer', 'Poland', 'Pollen', 'Weather'] | 21,573,820 | [['D23.050.063'], ['B01.650.940.800.575.912.250.859.750.200.750'], ['I01.320'], ['G17.485', 'L01.224.050.375.605'], ['Z01.542.248.679'], ['A18.024.249.500.249.500'], ['G16.500.275.063.725', 'G16.500.750.775', 'N06.230.300.100.725']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Evaluation of animal protein supplements in diets of early-weaned pigs. | Three growth assays were conducted to determine the efficacy of replacing dried skim milk and(or) dried whey in diets of starting pigs with commercially available spray-dried porcine plasma, spray-dried porcine blood, spray-dried bovine plasma, or spray-dried extracted meat protein. In Exp. 1, 236, 24-d-old crossbred p... | ['Animal Feed', 'Animals', 'Blood', 'Dairy Products', 'Dietary Proteins', 'Eating', 'Female', 'Food Hypersensitivity', 'Food, Fortified', 'Least-Squares Analysis', 'Male', 'Meat', 'Milk', 'Swine', 'Swine Diseases', 'Weaning', 'Weight Gain'] | 8,349,512 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['A12.207.152', 'A15.145'], ['G07.203.300.350', 'J02.500.350'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.283', 'G10.261.330'], ['C20.543.480.370'], ['G07.203.300.515', 'J02.500.515'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N0... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Origin and prediction of free-solution interaction studies performed label-free. | Interaction/reaction assays have led to significant scientific discoveries in the biochemical, medical, and chemical disciplines. Several fundamental driving forces form the basis of intermolecular and intramolecular interactions in chemical and biochemical systems (London dispersion, hydrogen bonding, hydrophobic, and... | ['Hydrogen Bonding', 'Interferometry', 'Models, Chemical', 'Protein Binding', 'Protein Conformation', 'Protein Folding', 'Refractometry', 'Sensitivity and Specificity', 'Solutions', 'Solvents', 'Water'] | 26,960,999 | [['G02.282'], ['E05.490'], ['E05.599.495'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688'], ['E05.196.808', 'H01.671.617.755'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['D26.776'],... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
GATA4 is essential for jejunal function in mice. | BACKGROUND & AIMS: Although the zinc-finger transcription factor GATA4 has been implicated in regulating jejunal gene expression, the contribution of GATA4 in controlling jejunal physiology has not been addressed.METHODS: We generated mice in which the Gata4 gene was specifically deleted in the small intestinal epithel... | ['Animals', 'Cholesterol, Dietary', 'DNA', 'Dietary Fats', 'Enterocytes', 'GATA4 Transcription Factor', 'Gene Expression', 'Ileum', 'Immunohistochemistry', 'Intestinal Absorption', 'Jejunum', 'Mice', 'Reverse Transcriptase Polymerase Chain Reaction', 'Zinc Fingers'] | 18,812,176 | [['B01.050'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['D13.444.308'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['A03.556.124.369.290', 'A10.615.550.444.290', 'A11.436.290'], ['D12.776.260.257.400', 'D12.776.930.314.400'], ['G05.297'], ['A03.556.124.684.249', 'A03.556.249.12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Recommendations of Common Data Elements to Advance the Science of Self-Management of Chronic Conditions. | PURPOSE: Common data elements (CDEs) are increasingly being used by researchers to promote data sharing across studies. The purposes of this article are to (a) describe the theoretical, conceptual, and definition issues in the development of a set of CDEs for research addressing self-management of chronic conditions; (... | ['Chronic Disease', 'Common Data Elements', 'Humans', 'Nursing Research', 'Self Care'] | 27,486,851 | [['C23.550.291.500'], ['L01.399.250.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['E02.900', 'I03.050.563', 'N02.421.784.680']] | ['Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Diet, lifestyle and cognitive function in old Chinese adults. | BACKGROUND: The relationship between diet, lifestyle and cognition of old adults has been indicated in several population-based studies. However, the conclusions derived from these studies are inconsistent.METHODS: A cross-sectional study was carried out in 894 old Chinese adults aged 50 and above. Cognitive function o... | ['Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'China', 'Cognition', 'Cross-Sectional Studies', 'Diet', 'Feeding Behavior', 'Female', 'Fruit', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Reading', 'Surveys and Questionnaires', 'Vegetables'] | 26,791,169 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['Z01.252.474.164'], ['F02.463.188'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.05... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
[The clinical efficacy and pharmacokinetic characteristics of theopek and theobiolong in bronchial asthma patients]. | The pharmacokinetics of theopec (TP) and theobiolong (TB) was studied and compared to theotard and durophylline in 24 bronchial asthma patients. The efficacy of the continuous use of TP and TB was examined in 64 patients. Theophylline (TPh) was absorbed from TP tablets according to the laws of the kinetics of the first... | ['Adult', 'Asthma', 'Delayed-Action Preparations', 'Drug Tolerance', 'Female', 'Humans', 'Tablets', 'Theophylline', 'Time Factors'] | 1,792,593 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D26.255.210', 'E02.319.300.253'], ['G07.690.773.992'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.255.830'], ['D03.132.960.751', 'D03.633.100.759.758.824.751'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of blood glucose management strategies to achieve control following cardiac surgery (computerized versus paper). | INTRODUCTION: Blood glucose control can be time-consuming and difficult to achieve. We hypothesized that a computerized system to obtain glucose control would enable faster "time to target" and produce less variability in blood glucose levels.METHODS: Patients who underwent cardiac surgery at a community hospital betwe... | ['Blood Glucose', 'Cardiovascular Surgical Procedures', 'Documentation', 'Humans', 'Monitoring, Physiologic', 'Therapy, Computer-Assisted'] | 20,431,443 | [['D09.947.875.359.448.500'], ['E04.100'], ['L01.453.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520'], ['E02.950', 'L01.313.500.750.100.710']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Piridoxilate-associated nephrocalcinosis: a new form of chronic oxalate nephropathy. | Piridoxilate is an association of glyoxylic acid and pyridoxine in which pyridoxine is supposed to facilitate in vivo transformation of glyoxylic acid to glycine rather than to oxalic acid. However, it has recently been shown that long-term treatment with piridoxilate may result in overproduction of oxalic acid and in ... | ['Aged', 'Calcium Oxalate', 'Glyoxylates', 'Humans', 'Kidney Calculi', 'Male', 'Nephrocalcinosis', 'Pyridoxine'] | 3,118,272 | [['M01.060.116.100'], ['D02.241.081.337.593.750.500'], ['D02.241.152.367'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['C12.777.419.590', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association of MicroRNAs with Antibody Response to Mycoplasma bovis in Beef Cattle. | The objective of this study was to identify microRNAs associated with a serum antibody response to Mycoplasma bovis in beef cattle. Serum from sixteen beef calves was collected at three points: in summer after calves were born, in fall at weaning, and in the following spring. All sera collected in the summer were ELISA... | ['Animals', 'Antibodies, Bacterial', 'Antibody Formation', 'Cattle', 'Cattle Diseases', 'Enzyme-Linked Immunosorbent Assay', 'Gene Library', 'Male', 'MicroRNAs', 'Mycoplasma Infections', 'Mycoplasma bovis'] | 27,537,842 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G12.450.050.370.250'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['G05.360.325']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Examination of the interaction between method of anesthesia and shunting with carotid endarterectomy. | BACKGROUND: Although the choice of anesthesia during carotid endarterectomy (CEA) does not seem to increase the risk of perioperative stroke, it might affect the outcomes of shunting during CEA. This study aims to evaluate whether the choice of anesthesia modifies the association between shunting and in-hospital stroke... | ['Aged', 'Anesthesia, General', 'Anesthesia, Local', 'Canada', 'Carotid Stenosis', 'Cerebrovascular Circulation', 'Endarterectomy, Carotid', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Registries', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Stroke', 'Time Factors', 'Treatment Out... | 31,699,512 | [['M01.060.116.100'], ['E03.155.197'], ['E03.155.086.231'], ['Z01.107.567.176'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['G09.330.100.159'], ['E04.100.814.456.250'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glycine-rich loop of mitochondrial processing peptidase alpha-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20. | Tryptophan fluorescence measurements were used to characterize the local dynamics of the highly conserved glycine-rich loop (GRL) of the mitochondrial processing peptidase (MPP) alpha-subunit in the presence of the substrate precursor. Reporter tryptophan residue was introduced into the GRL of the yeast alpha-MPP (Y299... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Base Sequence', 'Catalytic Domain', 'DNA, Fungal', 'Fluorescence Polarization', 'Glycine', 'Hydrophobic and Hydrophilic Interactions', 'Metalloendopeptidases', 'Mitochondrial Membrane Transport Proteins', 'Models, Molecular', 'Molecular Sequence D... | 20,053,354 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D13.444.308.300'], ['E05.196.712.516.600.390'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Occupational therapy practitioners' decision-making preferences, attitudes, awareness and barriers in relation to evidence-based practice implementation in Saudi Arabia. | AIM: Evidence-based practice (EBP) plays a significant part in healthcare. There has been little research into the standard of care that healthcare workers provide to patients in Saudi Arabia. The purpose of this study was to investigate occupational therapy practitioners' (OTPs) decision-making preferences, attitudes ... | ['Adult', 'Age Factors', 'Clinical Competence', 'Cross-Sectional Studies', 'Decision Making', 'Educational Status', 'Evidence-Based Practice', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Occupational Therapists', 'Saudi Arabia', 'Sex Factors', 'Socioeconomic Factors', 'Young Adu... | 30,870,266 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['N01.824.196'], ['H02.249'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Metastasis to pampiniform plexus from left renal adenocarcinoma presenting with acute varicocele. | A case of metastatic adenocarcinoma from the left kidney to the veins of the pampiniform plexus is described following initial presentation with an acute varicocele. It provides further evidence to support the retrograde venous route for intrascrotal secondary malignancy and also for low ligation of the left testicular... | ['Acute Disease', 'Adenocarcinoma', 'Aged', 'Genital Neoplasms, Male', 'Humans', 'Kidney Neoplasms', 'Male', 'Nephrectomy', 'Spermatic Cord', 'Testis', 'Varicocele'] | 6,506,405 | [['C23.550.291.125'], ['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.588.945.440', 'C12.294.260', 'C12.758.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E04.950.774.435'], ['A05.360.444.777'], [... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Action of dichlorobenzimidazole riboside on RNA synthesis in L-929 and HeLa cells. | 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) inhibits RNA synthesis in L-929 cells (mouse fibroblast line) and HeLa cells (human epitheloid carcinoma line) within 2 min of addition of the compound to the medium. By removing DRB from the medium, the inhibition is promptly and completely reversed after treatmen... | ['Benzimidazoles', 'Cell Nucleolus', 'Cell Nucleus', 'Dose-Response Relationship, Drug', 'HeLa Cells', 'Kinetics', 'L Cells', 'Leucine', 'Neoplasm Proteins', 'RNA, Neoplasm', 'Ribonucleosides', 'Uridine'] | 1,262,389 | [['D03.633.100.103'], ['A11.284.430.106.279.345.175'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G01.374.661', 'G02.111.490'], ['A11.251.210.505', 'A11.329.228.505'], ['D12.125.070.637', 'D12.125.142.441']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Step section preparation of transbronchial lung biopsy material in diffuse lung disease]. | We retrospectively prepared step sections of the transbronchial lung biopsy (TBLB) materials which revealed nondiagnostic findings in their original sections in patients with diffuse lung disease, and evaluated the significance of the examination of step sections in the diagnosis of diffuse lung disease. Of 131 cases w... | ['Biopsy', 'Humans', 'Lung', 'Lung Diseases', 'Microtomy', 'Retrospective Studies'] | 2,290,227 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381'], ['E01.370.225.500.620.530', 'E01.370.225.750.600.530', 'E05.200.500.620.530', 'E05.200.750.600.530'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Percutaneous sclerotherapy of congenital slow-flow vascular malformations of the orbit. | PURPOSE: This manuscript describes the clinical features, imaging findings, treatment details, and short-term outcomes of a series of congenital slow-flow vascular malformations.METHODS: This was a prospective study of congenital slow-flow vascular malformations involving the orbital region treated at a single institut... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Orbit', 'Orbital Diseases', 'Prospective Studies', 'Retreatment', 'Sclerotherapy', 'Treatment Outcome', 'Vascular Malformations'] | 25,148,921 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.690'], ['C11.675'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Altered keratin biosynthesis follows inhibition of scale morphogenesis by hydrocortisone. | Hydrocortisone, administered onto the chorioallantoic membrane (CAM) of 7- to 10-day-old chick embryos, inhibits scale development, in a dose- and stage-dependent manner. The response is also region specific in that hydrocortisone treatment, at a specific dose and time, will completely block scutellate and interstitial... | ['Allantois', 'Animals', 'Chick Embryo', 'Chorion', 'Dose-Response Relationship, Drug', 'Feathers', 'Hydrocortisone', 'Keratins', 'Morphogenesis'] | 6,208,069 | [['A10.615.284.147', 'A16.254.750.147'], ['B01.050'], ['A13.350.150', 'A16.331.200'], ['A10.615.284.473', 'A16.254.750.473'], ['G07.690.773.875', 'G07.690.936.500'], ['A13.370'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.77... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantum dot fluorescence characterizes the nanoscale organization of T cell receptors for antigen. | Changes in the clustering of surface receptors modulate cell responses to ligands. Hence, global measures of receptor clustering can be useful for characterizing cell states. Using T cell receptor for antigen as an example, we show that k-space image correlation spectroscopy of quantum dots blinking detects T cell rece... | ['Animals', 'Fluorescence', 'Lymphocyte Activation', 'Mice', 'Mice, Transgenic', 'Nanoparticles', 'Quantum Dots', 'Receptors, Antigen, T-Cell', 'Time Factors'] | 22,261,075 | [['B01.050'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['J01.637.512.600'], ['E07.705', 'J0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Frequency-spatial transformation: a proposal for parsimonious intra-cortical communication. | This work examines a neural network model of a cortical module, where neurons are organized on a 2-dimensional sheet and are connected with higher probability to their spatial neighbors. Motivated by recent findings that cortical neurons have a resonant peak in their impedance magnitude function, we present a frequency... | ['Cell Communication', 'Cerebral Cortex', 'Models, Neurological', 'Neurons'] | 9,040,060 | [['G04.085'], ['A08.186.211.200.885.287.500'], ['E05.599.395.642'], ['A08.675', 'A11.671']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biodegradability of ethylenediamine-based complexing agents and related compounds. | The biological degradability (Zahn-Wellens test) of ethylenediamine derivatives with carboxymethyl and 2-hydroxyethyl groups was investigated. Mixed bacterial culture (activated sludge) was used as inoculum (non-adapted sludge and sludge adapted at different mean biomass retention time, the so-called sludge age). Biode... | ['Bacteria', 'Biodegradation, Environmental', 'Biomass', 'Chelating Agents', 'Ethylenediamines', 'Sewage', 'Soil Microbiology', 'Soil Pollutants'] | 11,482,674 | [['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.092.782.258.368'], ['D20.944.932.500'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['D27.888.284.756']] | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Ciprofloxacin therapy of experimental endocarditis caused by methicillin-susceptible or methicillin-resistant Staphylococcus aureus. | Ciprofloxacin was more effective (P less than 0.01) than either imipenem or nafcillin therapy of experimental methicillin-susceptible Staphylococcus aureus endocarditis in rabbits after 2 or 3 days of treatment. There was no significant difference between results of treatment of methicillin-susceptible S. aureus experi... | ['Animals', 'Ciprofloxacin', 'Drug Therapy, Combination', 'Endocarditis, Bacterial', 'Gentamicins', 'Humans', 'Imipenem', 'Methicillin', 'Nafcillin', 'Penicillin Resistance', 'Rabbits', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Thienamycins', 'Vancomycin'] | 3,164,989 | [['B01.050'], ['D03.633.100.810.835.322.186'], ['E02.319.310'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.124.300.500', 'D03.633.100.300.124.300.500'], ['D02.065.589.099.750.500', 'D02.886.108.750.500', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Several indices of the methylation process in schizophrenic patients]. | The paper deals with a study of 83 patients with different forms of schizophrenia and 15 normals where the methylating activity in converting nicotinamid into methylnicotinamid was determined and the activity of catechol-methyltransferase. In schizophrenic patients there is an increase of the methylating activity which... | ['Adult', 'Antipsychotic Agents', 'Automatism', 'Catechol O-Methyltransferase', 'Depression', 'Female', 'Hallucinations', 'Humans', 'Isoproterenol', 'Male', 'Methylation', 'Middle Aged', 'Niacinamide', 'Schizophrenia', 'Schizophrenia, Catatonic', 'Schizophrenia, Paranoid', 'Syndrome'] | 19,907 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F02.463.425.179.149'], ['D08.811.913.555.500.250'], ['F01.145.126.350'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.100.29... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of methionine supplementation of a soy protein isolate on short-term nitrogen balance in young women. | The effect of L-methionine supplementation on the utilization of a soy protein isolate (SPI) was evaluated by short-term nitrogen balance studies in young women. Thirteen female students were given SPI in an initial period and SPI supplemented with 1% methionine in a second period immediately after menstruation as the ... | ['Adolescent', 'Adult', 'Energy Intake', 'Feces', 'Female', 'Food, Fortified', 'Humans', 'Methionine', 'Nitrogen', 'Nutritive Value', 'Plant Proteins, Dietary', 'Soybean Proteins'] | 3,712,106 | [['M01.060.057'], ['M01.060.116'], ['G07.203.650.240.340'], ['A12.459'], ['G07.203.300.515', 'J02.500.515'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['D01.268.604', 'D01.362.625'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
An idiographic statistical approach to clinical hypothesis testing for routine psychotherapy: A case study. | In order to develop more targeted, efficient, and effective psychotherapeutic interventions, calls have been made in the literature for greater use of idiographic hypothesis testing. Idiographic analyses can provide useful information regarding mechanisms of change within individuals over time during treatment. However... | ['Anxiety', 'Anxiety Disorders', 'Cognitive Behavioral Therapy', 'Depression', 'Humans', 'Male', 'Middle Aged', 'Statistics as Topic', 'Treatment Outcome'] | 30,991,265 | [['F01.470.132'], ['F03.080'], ['F04.754.137.350'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Pertubation with lignocaine--a possible new treatment for women with endometriosis and impaired fertility. | The causal relationship between reduced fertility and early stage endometriosis without pelvic adhesions is unclear. Peritoneal fluid from patients with endometrial peritoneal implants contains more leukocytes with an increased capacity to phagocytose spermatozoa. Peritoneal fluid supplemented with lignocaine has a red... | ['Adult', 'Anesthetics, Local', 'Dose-Response Relationship, Drug', 'Endometriosis', 'Female', 'Humans', 'Infertility, Female', 'Lidocaine', 'Male', 'Phagocytosis', 'Spermatozoa'] | 11,817,563 | [['M01.060.116'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['G07.690.773.875', 'G07.690.936.500'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['G04.417.350', 'G09.188.665... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Retrovirus-induced expression of interleukin 2 receptors on cells of human B-cell lineage. | We provide direct evidence for interleukin 2 receptor (IL2R) induction by human T-cell leukemia/lymphoma virus (HTLV) in human B-cell lines. A lymphoblastoid B-cell line (LCL-Ter) was established by Epstein-Barr virus-induced transformation of peripheral blood lymphocytes derived from a healthy HTLV carrier and cloned ... | ['Antigens, Surface', 'B-Lymphocytes', 'Cell Line', 'Cell Transformation, Viral', 'Deltaretrovirus', 'Herpesvirus 4, Human', 'Humans', 'Interleukin-2', 'Radioimmunoassay', 'Receptors, Immunologic', 'Receptors, Interleukin-2'] | 6,095,296 | [['D23.050.301'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.251.210'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['B04.613.807.200', 'B04.820.650.200'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Parapharyngeal growth of parotid tumors: report of two cases. | Two patients with parapharyngeal pleomorphic adenomas of the parotid gland, one malignant and one benign lesion, were successfully treated operatively. Deep lobe parotid tumors may occasionally grow along the stylomandibular tunnel into the parapharyngeal region. Since the opening of the tunnel is narrower and less dis... | ['Adenocarcinoma', 'Adult', 'Biopsy, Needle', 'Female', 'Humans', 'Male', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Palatal Neoplasms', 'Parotid Gland', 'Parotid Neoplasms', 'Pharyngeal Neoplasms'] | 871,248 | [['C04.557.470.200.025'], ['M01.060.116'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Green synthesis of highly stable carbon nanodots and their photocatalytic performance. | The present study reports a novel, facile, biosynthesis route for the synthesis of carbon nanodots (CDs) with an approximate quantum yield of 38.5%, using Musk melon extract as a naturally derived-precursor material. The synthesis of CDs was established by using ultraviolet-visible (UV-vis) spectroscopy, Dynamic light ... | ['Carbon', 'Catalysis', 'Coloring Agents', 'Drug Stability', 'Green Chemistry Technology', 'Light', 'Materials Testing', 'Nanoparticles', 'Particle Size', 'Photochemistry', 'Water Pollutants, Chemical', 'Water Purification'] | 28,530,182 | [['D01.268.150'], ['G02.130'], ['D27.720.233'], ['E05.916.330'], ['J01.897.360'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.570'], ['J01.637.512.600'], ['G02.712'], ['H01.181.529.711'], ['D27.888.284.903.655'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Bifunctional and multimeric complexes of streptavidin fused to single chain antibodies (scFv). | Multivalent and multispecific antibodies with defined stoichiometry could provide valuable tools for biological and medical research and for the diagnosis and therapy of cancer. We have therefore fused single chain antibodies (scFv) with core-streptavidin. This chimeric protein, expressed by the vector pSTE-215 (plasmi... | ['Amino Acid Sequence', 'Antibodies, Bispecific', 'Bacterial Proteins', 'Base Sequence', 'Chromatography, Affinity', 'Enzyme-Linked Immunosorbent Assay', 'Immunoglobulin Variable Region', 'Macromolecular Substances', 'Molecular Sequence Data', 'Recombinant Fusion Proteins', 'Streptavidin', 'Transfection'] | 7,836,782 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.125', 'D12.776.124.790.651.114.134', 'D12.776.377.715.548.114.134'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.170'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation. | Traumatic brain injury (TBI) is one of the major causes of death and disability worldwide. Novel and effective therapy is needed to prevent the secondary spread of damage beyond the initial injury. The aim of this study was to investigate whether berberine has a neuroprotective effect on secondary injury post-TBI, and ... | ['Animals', 'Anti-Inflammatory Agents', 'Antioxidants', 'Berberine', 'Brain', 'Brain Injuries, Traumatic', 'Male', 'Maze Learning', 'Mice, Inbred C57BL', 'Nitric Oxide Synthase Type II', 'Oxidative Stress'] | 30,027,364 | [['B01.050'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['A08.186.211'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['F02.463.425.874.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Video-assisted thoracic surgery major pulmonary resection requiring control of the main pulmonary artery. | The purpose of this study is to examine the feasibility and safety of thoracoscopic major pulmonary resection requiring the cross-clamping of the main pulmonary artery (PA), in comparison to an open thoracotomy performed in patients with lung cancer. A retrospective database of 27 consecutive lung cancer patients, who ... | ['Aged', 'Constriction', 'Feasibility Studies', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Patient Selection', 'Pneumonectomy', 'Pulmonary Artery', 'Risk Assessment', 'Risk Factors', 'Thoracic Surgery,... | 19,602,492 | [['M01.060.116.100'], ['E05.225'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of protein multiple alignments by SAM-T99 using the BAliBASE multiple alignment test set. | MOTIVATION: SAM-T99 is an iterative hidden Markov model-based method for finding proteins similar to a single target sequence and aligning them. One of its main uses is to produce multiple alignments of homologs of the target sequence. Previous tests of SAM-T99 and its predecessors have concentrated on the quality of t... | ['Computational Biology', 'Databases, Protein', 'Markov Chains', 'Proteins', 'Sequence Alignment', 'Software'] | 11,524,372 | [['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.8... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Microarrays reveal that each of the ten dominant lineages of Staphylococcus aureus has a unique combination of surface-associated and regulatory genes. | Staphylococcus aureus is the most common cause of hospital-acquired infection. In healthy hosts outside of the health care setting, S. aureus is a frequent colonizer of the human nose but rarely causes severe invasive infection such as bacteremia, endocarditis, or osteomyelitis. To identify genes associated with commun... | ['Carrier State', 'Genes, Bacterial', 'Genes, Regulator', 'Genetic Variation', 'Humans', 'Nasal Mucosa', 'Oligonucleotide Array Sequence Analysis', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Virulence Factors'] | 16,385,056 | [['N06.850.520.169'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.425'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.60... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bacterial lipopolysaccharide binds to CD14 in low-density domains of the monocyte-macrophage plasma membrane. | We report that gram-negative bacterial lipopolysaccharide (LPS) binds to CD14 on lipid-enriched, low-density domains of the human monocyte-macrophage (THP-1 cell) plasma membrane. After brief incubation with [3H]LPS under conditions that prevent its internalization, THP-1 cells were disrupted using a detergent-free met... | ['Cell Count', 'Cell Membrane', 'Cells, Cultured', 'Chromatography, Thin Layer', 'Enzyme Inhibitors', 'Escherichia coli', 'G(M1) Ganglioside', 'GTP-Binding Proteins', 'Humans', 'Immunoblotting', 'Lipopolysaccharide Receptors', 'Lipopolysaccharides', 'Macrophages', 'Microscopy, Immunoelectron', 'Monocytes', 'Ouabain', '... | 9,117,440 | [['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.284.149'], ['A11.251'], ['E05.196.181.400.537'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D09.400.410.420.025.475.390', 'D10.390.470.025.475.390', 'D10.570.877.360.025.475.390'], ['D08.811.277.040.330.300'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TFE3 contains two activation domains, one acidic and the other proline-rich, that synergistically activate transcription. | TFE3 is a basic-helix-loop-helix-zipper (bHLHZIP) domain-containing protein that binds mu E3 sites in regulatory elements in the immunoglobulin heavy chain gene. The protein is a transcriptional activator that is expressed in vivo as two alternately spliced isoforms with different activating properties: TFE3L contains ... | ['3T3 Cells', 'Amino Acid Sequence', 'Animals', 'Basic Helix-Loop-Helix Leucine Zipper Transcription Factors', 'Binding Sites', 'DNA', 'DNA-Binding Proteins', 'Fungal Proteins', 'Gene Expression Regulation', 'Helix-Loop-Helix Motifs', 'Immunoglobulin Heavy Chains', 'Leucine Zippers', 'Luciferases', 'Mice', 'Models, Mol... | 7,479,029 | [['A11.251.210.100', 'A11.329.228.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.260.103.500', 'D12.776.260.108.092', 'D12.776.930.125.500', 'D12.776.930.127.092'], ['G02.111.570.120'], ['D13.444.308'], ['D12.776.260'], ['D12.776.354'], ['G05.308'], ['G02.111.570.820.709.275.500.360'], ['D12.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis. | CONTEXT: Studies suggest little benefit in relief of acute sinusitis symptoms from the use of newer and more expensive (second-line) antibiotics instead of older and less expensive (first-line) antibiotics. However, researchers have failed to include development of complications and cost of care in their analyses.OBJEC... | ['Acute Disease', 'Adult', 'Analysis of Variance', 'Anti-Bacterial Agents', 'Cost-Benefit Analysis', 'Drug Utilization', 'Female', 'Humans', 'Logistic Models', 'Male', 'Outcome Assessment, Health Care', 'Retrospective Studies', 'Sinusitis', 'Treatment Outcome', 'United States'] | 11,597,286 | [['C23.550.291.125'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.954.122.085'], ['N03.219.151.125'], ['N04.452.706.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
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