Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[Outflow pathways of venous blood from the myocardium in the dog and structures participating in their regulation]. | The intramural pathways of the venous blood outflow from the cardiac wall have been studied histologically, histochemically and micrometrically in 20 control and 84 experimental dogs with an artificially produced circulatory disturbances, peculiar for congenital heart disease (open arterial canal, coarctation of the ao... | ['Adaptation, Physiological', 'Animals', 'Aortic Coarctation', 'Coronary Circulation', 'Coronary Vessels', 'Dogs', 'Ductus Arteriosus, Patent', 'Heart Defects, Congenital', 'Hemodynamics', 'Pulmonary Valve Stenosis', 'Veins'] | 4,091,682 | [['G07.025', 'G16.012.500'], ['B01.050'], ['C14.240.400.090', 'C14.280.400.090', 'C16.131.240.400.090'], ['G09.330.100.324'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['C14.240.400', 'C14.280.400', 'C16.131.240.40... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Composite adrenal phaeochromocytoma-ganglioneuroma causing watery diarrhoea, hypokalaemia and achlorhydria syndrome. | The watery diarrhoea, hypokalaemia and achlorhydria syndrome is a rare cause of secretory diarrhoea. In this case report, we highlight a young female with watery diarrhoea, hypokalaemia and achlorhydria syndrome as a consequence of a vasoactive intestinal peptide producing composite adrenal phaeochromocytoma-ganglioneu... | ['Achlorhydria', 'Adrenal Gland Neoplasms', 'Diarrhea', 'Female', 'Ganglioneuroma', 'Humans', 'Hypokalemia', 'Pheochromocytoma', 'Vasoactive Intestinal Peptide', 'Young Adult'] | 20,216,072 | [['C06.405.748.045', 'C18.452.076.087'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['C23.888.821.214'], ['C04.557.465.625.600.355', 'C04.557.470.670.355', 'C04.557.580.625.600.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.565'], ['C04.557.465.625.650.700.725', 'C04.557.580.625.650.700.7... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Microenvironmental analysis of two alternating hosts and their impact on the ecological adaptation of the horned sumac gall aphid Schlechtendalia chinensis (Hemiptera, Pemphiginae). | The aphid Schlechtendalia chinensis(Bell) induces horned galls on their primary host Rhus chinensis(Mill). These galls serve as closed habitats to support thousands of aphids per gall. Ecological parameters inside a gall are unknown. In this study, we showed that the microclimate inside galls was reltively stable, with... | ['Adaptation, Physiological', 'Animals', 'Aphids', 'Environment', 'Host Specificity', 'Humidity', 'Light', 'Temperature'] | 31,949,256 | [['G07.025', 'G16.012.500'], ['B01.050'], ['B01.050.500.131.617.412.165'], ['G16.500.275', 'N06.230'], ['G06.462.380', 'G16.527.200.380'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G01... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibitory effect of cryptoporic acid E, a product from fungus Cryptoporus volvatus, on colon carcinogenesis induced with N-methyl-N-nitrosourea in rats and with 1,2-dimethylhydrazine in mice. | The antitumorigenic effect of cryptoporic acid E (CPA-E), a dimeric drimane sesquiterpenoid isolated from the fungus Cryptoporus volvatus, on colon carcinogenesis was investigated. Female F344 rats given an intrarectal instillation of 2 mg of N-methyl-N-nitrosourea 3 times weekly in weeks 1 and 2 were fed diet containi... | ['1,2-Dimethylhydrazine', 'Animals', 'Anticarcinogenic Agents', 'Biomarkers, Tumor', 'Carcinogens', 'Colon', 'Colonic Neoplasms', 'Deoxycholic Acid', 'Dimethylhydrazines', 'Enzyme Induction', 'Feeding Behavior', 'Female', 'Intestinal Mucosa', 'Methylnitrosourea', 'Mice', 'Mice, Inbred ICR', 'Ornithine Decarboxylase', '... | 1,399,820 | [['D02.442.600.400.200'], ['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D23.101.140'], ['D27.888.569.100'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.49... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seroprevalence of coeliac disease in at-risk subjects at the main tertiary hospital, southwest of Saudi Arabia. | BACKGROUND AND STUDY AIMS: Coeliac disease (CD) is a gluten-induced autoimmune inflammation of small bowel villi, leading to atrophy and malabsorption. The current study aims to assess the prevalence of CD in high-risk subjects in the Aseer region, southwest of Saudi Arabia and to investigate the associated presentatio... | ['Adolescent', 'Adult', 'Aged', 'Autoantibodies', 'Body Height', 'Celiac Disease', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Female', 'GTP-Binding Proteins', 'Humans', 'Hypothyroidism', 'Infant', 'Male', 'Middle Aged', 'Prevalence', 'Retrospective Studies', 'Risk Factors', 'Saudi Arabia', 'Seroepidemio... | 27,067,921 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['M01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
We should de-emphasize the importance of the role we give amines in the LH syndrome. | Once amines were implicated in the lateral hypothalamic syndrome, it became accepted that the dominant cause of many of its symptoms was an alteration in amines. We suggest that corticofugal fiber damage may produce some of the behavioral symptoms usually attributed to amine alterations. | ['Animals', 'Body Weight', 'Catecholamines', 'Cerebral Cortex', 'Dominance, Cerebral', 'Drinking', 'Eating', 'Hypothalamic Area, Lateral', 'Motor Activity', 'Motor Neurons', 'Mouth', 'Neural Pathways', 'Rats'] | 6,524,920 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A08.186.211.200.885.287.500'], ['F02.830.297', 'G11.561.225'], ['G07.203.650.283.249', 'G10.261.330.249'], ['G07.203.650.283', 'G10.261... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mycobacterium tuberculosis pncA Polymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT. | Sequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms that do not confer resistance at a susceptibility breakpoint of 100 ìg/ml pyrazinamide in MGIT within a cohort of isolates from South Africa and the U.S. Centers for Disease Con... | ['Amidohydrolases', 'Antitubercular Agents', 'Base Sequence', 'DNA, Bacterial', 'Drug Resistance, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Mycobacterium tuberculosis', 'Polymorphism, Single Nucleotide', 'Pyrazinamide', 'Sequence Analysis, DNA', 'South Africa', 'United States'] | 26,292,310 | [['D08.811.277.087'], ['D27.505.954.122.085.255'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.510.024.962.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
An exonic splicing enhancer within a bidirectional coding sequence regulates alternative splicing of an antisense mRNA. | The discovery of increasing numbers of genes with overlapping sequences highlights the problem of expression in the context of constraining regulatory elements from more than one gene. This study identifies regulatory sequences encompassed within two genes that overlap in an antisense orientation at their 3' ends. The ... | ['Alternative Splicing', 'Base Sequence', 'Cluster Analysis', 'Enhancer Elements, Genetic', 'Evolution, Molecular', 'Exons', 'Humans', 'Introns', 'Molecular Sequence Data', 'Nuclear Receptor Subfamily 1, Group D, Member 1', 'Open Reading Frames', 'RNA Processing, Post-Transcriptional', 'RNA Splice Sites', 'RNA, Antisen... | 20,200,494 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['G05.045.250', 'G16.075.250'], ['G05.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
r | A theory-driven tailored intervention developed in partnership with the community used evidence-based practices to (a) increase knowledge about colon cancer and screening and (b) assist patients in completing screenings. During the 16 months of delivery screening, patient navigators integrated into gastroenterology cli... | ['Colonoscopy', 'Colorectal Neoplasms', 'Early Detection of Cancer', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Patient Acceptance of Health Care', 'Patient Education as Topic', 'Patient Navigation', 'Research Design'] | 29,421,953 | [['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.390.500'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Longitudinal evaluation of computerized cardiotocographic parameters throughout pregnancy in normal fetuses: a prospective cohort study. | INTRODUCTION: The longitudinal cardiotocographic (CTG) changes throughout pregnancy in normal fetuses have never been fully described. We aimed at characterizing the evolution of CTG parameters in healthy fetuses, from 24 to 41 weeks of gestation.MATERIAL AND METHODS: A prospective cohort study was conducted in singlet... | ['Adult', 'Cardiotocography', 'Diagnosis, Computer-Assisted', 'Female', 'Heart Rate, Fetal', 'Humans', 'Longitudinal Studies', 'Pregnancy', 'Pregnancy Complications', 'Prospective Studies', 'Young Adult'] | 27,238,561 | [['M01.060.116'], ['E01.370.370.380.170', 'E01.370.378.230.150', 'E01.370.520.230.150'], ['E01.158', 'L01.313.500.750.100.158'], ['G09.330.380.500.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['G08.686.784.769'], ['C13... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
An improved method of hydrogen production as electron donor for anaerobic bioremediation. | This paper investigated an improved electrochemical approach that is able to provide hydrogen for anaerobic bioremediation of chloroethenes in subsurface. Hydrogen is the ultimate electron donor of biodechlorination processes. In experiments, iron wire was used as electrodes, an anaerobic bacteria enrichment collected ... | ['Bacteria, Anaerobic', 'Biodegradation, Environmental', 'Environmental Pollutants', 'Hydrogen', 'Tetrachloroethylene'] | 11,688,682 | [['B03.130'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D27.888.284'], ['D01.268.406', 'D01.362.340'], ['D02.455.526.439.880']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of ammonia exposure on apoptosis, oxidative stress and immune response in pufferfish (Takifugu obscurus). | Ammonia is one of major environmental pollutants in the freshwater aquatic system that affects the survival and growth of organisms. In the present study, we investigated the effects of ammonia exposure on apoptosis, oxidative stress and immune response in pufferfish (Takifugu obscurus). Fish were exposed to various co... | ['Ammonia', 'Animals', 'Apoptosis', 'DNA Damage', 'Fish Proteins', 'Gene Expression Regulation', 'Immune System', 'Liver', 'Oxidative Stress', 'Signal Transduction', 'Takifugu', 'Water Pollutants, Chemical'] | 25,917,764 | [['D01.362.075', 'D01.625.050'], ['B01.050'], ['G04.146.954.035'], ['G05.200'], ['D12.776.325'], ['G05.308'], ['A15.382'], ['A03.620'], ['G03.673', 'G07.775.750'], ['G02.111.820', 'G04.835'], ['B01.050.150.900.493.875.800'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetics of PTT-119 in man. | The pharmacokinetics of PTT-119, a new alkylating agent, was studied in 8 advanced cancer patients. PTT-119 disappeared rapidly from plasma after administration at a dose of 3 mg/kg by i.v. bolus injection. The HPLC method shows plasma levels of m-bis (dichloroethyl)amino-phenyl-L-alanine which is the major metabolite ... | ['Aged', 'Antineoplastic Agents', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Nitrogen Mustard Compounds'] | 3,396,115 | [['M01.060.116.100'], ['D27.505.954.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['D02.455.526.728.650']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression, characterization and 2,4,6-trichlorophenol degradation of laccase from Monilinia fructigena. | A novel laccase gene from Monilinia fructigena was synthesized chemically according to the yeast bias codon and integrated into the genome of Pichia pastoris GS115 by electroporation. The expressed enzyme was recovered from the culture supernatant and purified. The result of enzyme activity assay and SDS-PAGE demonstra... | ['Ascomycota', 'Benzothiazoles', 'Biodegradation, Environmental', 'Chlorophenols', 'Chromatography, High Pressure Liquid', 'Copper', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme Stability', 'Genetic Vectors', 'Guaiacol', 'Indicators and Reagents', 'Ions', 'Isoelectric Point', 'Kinetics', 'Laccase', 'Molecular Weight'... | 21,743,993 | [['B01.300.107'], ['D03.383.129.708.089', 'D03.633.100.185'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['E05.196.181.400.300'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.916.360', 'G02.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Altered expression of AT-rich interactive domain 1A in hepatocellular carcinoma. | AT-rich interactive domain 1A (ARID1A) is a subunit of the Switch/Sucrose non-fermentable (SWI/SNF) chromatin remodeling complex. Recently, genome-wide whole exome sequencing revealed frequent mutations of ARID1A in hepatocellular carcinoma, but clinicopathological significance of ARID1A alteration has not been clarifi... | ['Biomarkers, Tumor', 'Carcinoma, Hepatocellular', 'Cell Differentiation', 'DNA-Binding Proteins', 'Disease-Free Survival', 'Female', 'Hepatectomy', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Nuclear Proteins', 'Risk Factors', 'Time Factors', 'Tissue Array Anal... | 26,045,782 | [['D23.101.140'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.152'], ['D12.776.260'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E04.210.556'], ['B01.050... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of selective neck dissection (I-III) in the treatment of node negative (N0) neck in oral cancer. | It is now possible to limit the extent of selective neck dissection for mucosal squamous cell carcinoma of the head and neck by sparing selected lymphatic levels thereby reducing the morbidity. This has been brought about by our improved understanding of the metastasis behavior of these cancers. Studies have demonstrat... | ['Aged', 'Carcinoma, Squamous Cell', 'Disease-Free Survival', 'Female', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Neck Dissection', 'Neoplasm Staging', 'Prognosis', 'Radiotherapy, Adjuvant', 'Retrospective Studies'] | 18,486,527 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ontogeny of humoral heart rate regulation in the embryonic mouse. | Catecholamines, acetylcholine, and adenosine are known to influence cardiac function, yet the effects of these agents on mammalian embryonic myocardium are largely unknown. To address this issue, we compared the chronotrophic effects of adenosinergic, adrenergic, and muscarinic agents on cultured murine embryos from po... | ['Adenosine', 'Adrenergic Agents', 'Age Factors', 'Animals', 'Cholinergic Agents', 'Culture Techniques', 'Dose-Response Relationship, Drug', 'Female', 'Heart', 'Heart Rate', 'Male', 'Mice', 'Myocardial Contraction', 'Receptors, Adrenergic, beta', 'Receptors, Muscarinic', 'Receptors, Purinergic P1'] | 11,448,841 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D27.505.519.625.050', 'D27.505.696.577.050'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D27.505.519.625.120', 'D27.505.696.577.120'], ['E05.481.500'], ['G07.690.773.875', 'G07.690.936.500'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Plasma growth hormone and insulin during early lactation in cows fed silage based diets. | Peripheral plasma insulin, growth hormone, and blood glucose were determined in 24 dairy cows during early lactation. Blood samples were obtained at 4-day intervals during the first 56 days of experimental lactations 1 and 3 of a 3-lactation experiment. The cows were divided equally among three groups and fed one of th... | ['Animal Feed', 'Animals', 'Blood Glucose', 'Cattle', 'Female', 'Growth Hormone', 'Insulin', 'Labor, Obstetric', 'Lactation', 'Medicago sativa', 'Poaceae', 'Pregnancy', 'Silage', 'Time Factors', 'Zea mays'] | 1,249,290 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D09.947.875.359.448.500'], ['B01.050.150.900.649.313.500.380.271'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G08.686.784.769.326'], ['G08.686.523', 'G08.686.702.500'], ['B01.650.9... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex. | The entorhinal cortex (EC) plays a central role in episodic memory and is among the earliest sites of neurodegeneration and neurofibrillary tangle formation in Alzheimer's disease. Given its importance in memory and dementia, the ability to selectively modulate gene expression or neuronal function in the EC is of wides... | ['Amyloid beta-Protein Precursor', 'Animals', 'Brain', 'Entorhinal Cortex', 'Galactosides', 'Genes, Reporter', 'Humans', 'Immunohistochemistry', 'Indoles', 'Kallikreins', 'Lac Operon', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Promoter Regions, Genetic', 'Tetracycline', 'Trans-Activators'] | 25,869,275 | [['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['A08.186.211'], ['A08.186.211.180.590.750.225', 'A08.186.211.180.710.225', 'A08.186.211.200.885.287.500.382.750.225', 'A08.186.211.200.885.287.500.620.562', 'A08.186.211.200.885.287.500.814.695.374', 'A08.186.211.200.88... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Congenital diaphragmatic hernia repair during whole body hypothermia for neonatal hypoxic ischemic encephalopathy. | Major malformations, surgery and persistent pulmonary hypertension (PHT) have been considered contraindications to therapeutic hypothermia (TH) in newborns with hypoxic-ischemic encephalopathy (HIE). We report two patients with undiagnosed congenital diaphragmatic hernia (CDH) who developed HIE after birth. Diagnosis o... | ['Female', 'Follow-Up Studies', 'Hemodynamics', 'Hernia, Diaphragmatic', 'Hernias, Diaphragmatic, Congenital', 'Herniorrhaphy', 'Humans', 'Hypothermia, Induced', 'Hypoxia-Ischemia, Brain', 'Infant, Newborn', 'Pregnancy', 'Respiratory Function Tests', 'Risk Assessment', 'Sampling Studies', 'Treatment Outcome', 'Ultrason... | 23,190,939 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G09.330.380'], ['C23.300.707.960.500'], ['C16.131.433', 'C23.300.707.960.500.116'], ['E04.680.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['C10.228.140.300.150.716', 'C10.228.140.624.500', 'C14.907... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Luteal phase support with 17alpha-hydroxyprogesterone versus unsupported cycles in in vitro fertilization: a comparative randomized study. | This study was designed to determine the efficacy of 17alpha-hydroxyprogesterone caproate (17-OHPc) for luteal phase support in in vitro fertilization (IVF). For this purpose, a total of 86 IVF patients undergoing embryo transfer were randomly allocated to two groups as follows: (1) group A, including 43 patients who r... | ['17-alpha-Hydroxyprogesterone', 'Adult', 'Cleavage Stage, Ovum', 'Embryo Transfer', 'Estradiol', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Female', 'Luteal Phase', 'Ovary', 'Pregnancy', 'Progesterone'] | 10,460,994 | [['D04.210.500.745.745.654.829.395.400', 'D06.472.334.851.687.750.478.400'], ['M01.060.116'], ['A16.166'], ['E02.875.800.500', 'E05.820.800.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['G... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
What is the variability in urodynamic parameters with position change in children? Analysis of a prospectively enrolled cohort. | PURPOSE: Insufficient data are available regarding the effect of patient position on urodynamic parameters and diagnoses in children. We report on a cohort of pediatric patients, comparing the results of serial urodynamic studies to determine the variability between the supine and sitting positions.MATERIALS AND METHOD... | ['Chi-Square Distribution', 'Child', 'Child, Preschool', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Posture', 'Pressure', 'Probability', 'Prospective Studies', 'Sensitivity and Specificity', 'Statistics, Nonparametric', 'Urinary Bladder', 'Urinary Bladder, Overactive', 'Urination', 'Urodynamics'] | 17,945,305 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.695'], ['G01.374.715'], ['E05.318.740.600', 'G17.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Results of urethral reconstruction in adults after multiple hypospadias repairs]. | AIM: To improve treatment results in patients after multiple hypospadias repairs by optimizing the postoperative management.MATERIALS AND METHODS: Eighty-two patients (mean age 48.1+/-15.3 years) with urethral strictures secondary to failed hypospadias repairs underwent staged graft urethroplasty using oral mucosa (che... | ['Female', 'Humans', 'Hypospadias', 'Male', 'Middle Aged', 'Mouth', 'Postoperative Complications', 'Postoperative Period', 'Reconstructive Surgical Procedures', 'Treatment Outcome', 'Urethra', 'Urologic Surgical Procedures'] | 28,631,912 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.939.516'], ['M01.060.116.630'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['C23.550.767'], ['E04.614.750', 'N02.421.585.753.750'], ['E04.680'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.57... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A new family of repetitive nucleotide sequences is restricted to the genus Zea. | We have isolated a new family of moderately repetitive nucleotide sequences (about 2500 copies per haploid genome) specific to the genus Zea and absent in other graminaceous species. These sequences are interspersed in the genome and they show the same genomic organization pattern and similar copy number in all the Zea... | ['Base Sequence', 'Blotting, Northern', 'Blotting, Southern', 'DNA', 'Methylation', 'Molecular Sequence Data', 'Repetitive Sequences, Nucleic Acid', 'Species Specificity', 'Transcription, Genetic', 'Zea mays'] | 1,937,012 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['D13.444.308'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['L01.453.245.667'], ['G02.111.570.080.708', 'G05.360.080.708'], ['G16.824'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Decreased acute toxicities of intensity-modulated radiation therapy for localized prostate cancer with prostate-based versus bone-based image guidance. | BACKGROUND: Intensity-modulated radiation therapy (IMRT) is a major therapeutic option for localized prostate cancer. Image-guided radiation therapy (IGRT) allows tumor visualization and corrects the errors caused by daily internal movement of the prostate. The current study retrospectively compared the acute toxicitie... | ['Aged', 'Aged, 80 and over', 'Cohort Studies', 'Cone-Beam Computed Tomography', 'Fiducial Markers', 'Gastrointestinal Diseases', 'Humans', 'Male', 'Middle Aged', 'Organ Sparing Treatments', 'Organs at Risk', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Radiotherapy, Image-Guided', 'Radio... | 28,756,594 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['E05.978.808.249', 'E07.695.237', 'E07.710.259'], ['C06.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Value of flow diagrams in reports of randomized controlled trials. | CONTEXT: Diagrams of the flow of participants through a clinical trial are recommended in the Consolidated Standards for Reporting of Trials (CONSORT) statement, but it is unclear whether such flow diagrams improve the quality of trial reports.OBJECTIVE: To examine the information contributed by flow diagrams and the c... | ['Algorithms', 'Publishing', 'Quality Control', 'Randomized Controlled Trials as Topic'] | 11,308,437 | [['G17.035', 'L01.224.050'], ['L01.737'], ['J01.897.608'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
A new experience of auditory brainstem implantation in Malaysia. | Auditory brainstem implantation (ABI) is the only solution to restore hearing when cochlear nerves are disrupted together with the pathologies where bilateral cochleae do not provide a suitable location for cochlear implantation. We reported first two successful auditory brainstem implantation cases in patients with ne... | ['Adult', 'Auditory Brain Stem Implantation', 'Auditory Brain Stem Implants', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Neurofibromatosis 2', 'Neuroma, Acoustic'] | 30,350,824 | [['M01.060.116'], ['E04.580.450.109', 'E04.650.155'], ['E07.305.250.319.381.500.249', 'E07.695.075', 'E07.695.202.381.500.249', 'E07.814.458.074'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.595.610.500', 'C04... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fracture resistance of teeth directly and indirectly restored with composite resin and indirectly restored with ceramic materials. | PURPOSE: To evaluate the fracture resistance of teeth restored with direct and indirect restorations of composite resin and restored with indirect ceramic restorations.MATERIAL AND METHODS: Fifty-six maxillary premolar teeth were chosen and divided at random into seven equal groups; Group 1 (control): intact teeth; Gro... | ['Aluminum Silicates', 'Analysis of Variance', 'Bicuspid', 'Composite Resins', 'Compressive Strength', 'Dental Cavity Preparation', 'Dental Porcelain', 'Dental Restoration, Permanent', 'Dental Stress Analysis', 'Glass Ionomer Cements', 'Humans', 'Inlays', 'Materials Testing', 'Random Allocation', 'Silicate Cement', 'To... | 12,691,276 | [['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A14.549.167.860.150'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['G01.374.18... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Apparent amnesia on experimental memory tests in dissociative identity disorder: an exploratory study. | Dissociative identity disorder (DID; called multiple personality disorder in DSMIII-R) is a psychiatric condition in which two or more identity states recurrently take control of the person's behavior. A characteristic feature of DID is the occurrence of apparently severe amnestic symptoms. This paper is concerned with... | ['Adult', 'Amnesia', 'Dissociative Identity Disorder', 'Female', 'Humans', 'Memory', 'Middle Aged', 'Netherlands', 'Psychological Theory'] | 9,521,830 | [['M01.060.116'], ['C10.597.606.525.100', 'C23.888.592.604.529.100', 'F01.700.625.100', 'F03.615.200'], ['F03.300.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['M01.060.116.630'], ['Z01.542.651'], ['F02.739']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Met-enkephalin induced escape from dexamethasone immunosuppression. | The present study was undertaken to examine whether and what type of interaction occurs between a synthetic glucocorticoid, dexamethasone (DEX) and an opioid peptide, met-enkephalin (MENK) upon superoxide anion (O2-) release from human polymorphonuclear cells (PMN). MENK (10(-8) M) abolished suppressed O2- release from... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Dexamethasone', 'Enkephalin, Methionine', 'GTP-Binding Proteins', 'Humans', 'Immunosuppressive Agents', 'Isoquinolines', 'Neutrophils', 'Pertussis Toxin', 'Piperazines', 'Protein Kinase C', 'Respiratory Burst', 'Superoxides', 'Tetradecanoylphorbol Acetate', 'Virulence ... | 8,247,257 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['D03.633.100.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Application of a system dynamics model in forecasting the supply and age distribution of physicians. | AIM: To predict the future supply and age distribution of physicians with a simulation model, which can be used as an advising tool for policymakers who decide on enrollment and specialization training (ST) quotas at the national level.METHODS: A simulation model was created using the system dynamics (SD) method. Chang... | ['Adult', 'Age Distribution', 'Computer Simulation', 'Croatia', 'Forecasting', 'Humans', 'Middle Aged', 'Physicians'] | 32,378,376 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['L01.224.160'], ['Z01.542.248.295'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.485.810', 'N02.360.810']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Comparative studies to determine the efficiency of 6 methylpurine deoxyriboside to detect cell culture mycoplasmas. | Studies were performed to compare three methods to detect mycoplasmal infection of cell cultures. The methods included microbiological assay by inoculation into broth and onto agar with anaerobic incubation, fluorescent DNA staining by Hoechst 33258, and mycoplasmal mediated cytotoxicity by 6 methylpurine deoxyriboside... | ['Bisbenzimidazole', 'Cell Survival', 'Cells, Cultured', 'Culture Techniques', 'DNA, Bacterial', 'Humans', 'Mycoplasmatales', 'Purine Nucleosides', 'Staining and Labeling'] | 2,428,802 | [['D03.633.100.103.145'], ['G04.346'], ['A11.251'], ['E05.481.500'], ['D13.444.308.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.860.580'], ['D03.633.100.759.590', 'D13.570.583'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the determination of association constants of proteins by electrophoresis measurements. | During the electrophoresis of a reversibly associating substance the concentration profile is determined by diffusion, migration and reaction. The influence of the diffusion can be eliminated by extrapolating the concentration profiles, taken at different times and suitably transformed, to infinite time. This leads to ... | ['Chemical Phenomena', 'Chemistry', 'Electrophoresis', 'Lactoglobulins'] | 427,246 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete cartilaginous duplication of the rib cage found in a cadaver: a first reported case. | We discovered a unique case of complete cartilaginous duplication of the rib cage in a cadaver, never previously described in the literature. A retrospective review of the patient's medical records revealed an antecedent history of progressive tobacco-related emphysema leading to death from end stage respiratory failur... | ['Aged', 'Aged, 80 and over', 'Cadaver', 'Cartilage', 'Humans', 'Male', 'Ribs'] | 8,895,726 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.260.224'], ['A02.165', 'A10.165.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.570.500']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preparation of a partially calcified gelatin membrane as a model for a soft-to-hard tissue interface. | Cartilage and/or bone tissue engineering is a very challenging area in modern medicine. Since cartilage is an avascular tissue with limited capacity for self-repair, using scaffolds provides a promising option for the repair of severe cartilage damage caused by trauma, age-related degeneration, and/or diseases. Our aim... | ['Calcium', 'Crystallization', 'Diffusion', 'Gelatin', 'Gels', 'Hardness', 'Models, Biological', 'Phosphates', 'Surface Properties', 'Tissue Engineering', 'Tissue Scaffolds'] | 23,231,089 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.196.300', 'G02.171'], ['G01.202', 'G02.196'], ['D12.776.860.476'], ['D20.280.320', 'D26.255.165.320'], ['G01.374.647'], ['E05.599.395'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['G02.860'], ['E05.481.500.311.500', 'J01.293.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pharmacological management of chronic pain: a clinician's perspective. | Of the currently available mu agonist drugs, the following are relatively contraindicated: 1. Methadone--unpredictable duration of action [5]. 2. Pethidine--unwanted central effects, metabolised to an active metabolite and too short acting. 3. Codeine--too weak and with constipating side-effects. 4. Fentanyl--too short... | ['Analgesics', 'Chronic Disease', 'Contraindications', 'Humans', 'Narcotics', 'Pain', 'Physicians', 'Receptors, Opioid, mu'] | 7,879,706 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['C23.550.291.500'], ['E02.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.760', 'D27.505.954.427.040.550', 'D27.505.954.427.210.600'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['M01.526.485.8... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oxidative treatment characteristics of biotreated textile-dyeing wastewater and chemical agents used in a textile-dyeing process by advanced oxidation process. | The oxidative treatment characteristics of biotreated textile-dyeing wastewater and typical chemicals such as desizing, scouring, dispersing and swelling agents used in the textile-dyeing process by advanced oxidation process were experimentally studied. The refractory organic matters remained in the effluent of biolog... | ['Bioreactors', 'Carbon Dioxide', 'Coloring Agents', 'Hydrogen Peroxide', 'Organic Chemicals', 'Oxidants', 'Oxidants, Photochemical', 'Oxidation-Reduction', 'Ozone', 'Textile Industry', 'Waste Disposal, Fluid', 'Water Purification'] | 15,137,417 | [['E07.115', 'J01.897.120.115'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D27.720.233'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D02'], ['D27.720.642', 'D27.888.569.540'], ['D27.720.642.631', 'D27.888.569.540.631'], ['G02.700', 'G03.295.531'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Noradrenaline innervation of the spinal cord studied by the horseradish peroxidase method combined with monoamine oxidase staining. | The origin of the spinal cord noradrenaline (NA) has been investigated by means of the horseradish peroxidase (HRP) method, combined with monoamine oxidase staining (Glenner) to identify the NA neurons. Following the injection of HRP to the various levels of rat spinal cord, cervical to sacral cord, A1-3, 5-7 NA neuron... | ['Adrenergic Fibers', 'Animals', 'Axons', 'Histocytochemistry', 'Horseradish Peroxidase', 'Locus Coeruleus', 'Male', 'Medulla Oblongata', 'Monoamine Oxidase', 'Norepinephrine', 'Olivary Nucleus', 'Peroxidases', 'Pons', 'Rats', 'Reticular Formation', 'Spinal Cord', 'Staining and Labeling'] | 74,341 | [['A08.675.100.500', 'A08.675.542.075', 'A11.671.501.075'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['D08.811.682.732.512'], [... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of size and site of cerebral lesions on spontaneous recovery of aphasia and on success of language therapy. | Changes in linguistic competence were assessed with the Aachen Aphasia Test in 18 aphasic patients across 8 weeks of spontaneous recovery, 8 weeks of intensive language therapy, and after a follow-up period of 8 weeks without therapy. CT scans were obtained from all patients and were evaluated for size of lesion and fo... | ['Adult', 'Aged', 'Aphasia', 'Female', 'Humans', 'Language Disorders', 'Language Tests', 'Male', 'Middle Aged', 'Speech Therapy', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 7,859,059 | [['M01.060.116'], ['M01.060.116.100'], ['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.500', 'C23.888.592.604.150.500'], ['F04.711.513.240'], ['M01.060.116.630'], ['E02.760.169.063.500.727.552', 'E02.831.727.552'], ['E01.370.350.350.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transcriptome reveals involvement of immune defense, oxidative imbalance, and apoptosis in ammonia-stress response of the black tiger shrimp (Penaeus monodon). | Ammonia is a major aquatic environmental pollutant that negatively impacts shrimp health and commercial productivity. However, we currently do not fully understand the underlying molecular mechanisms of ammonia stress in shrimp. We therefore performed transcriptomic analysis of hepatopancreas from black tiger shrimp (P... | ['Ammonia', 'Animals', 'Apoptosis', 'Arthropod Proteins', 'Environmental Pollutants', 'Gene Expression Profiling', 'Hepatopancreas', 'Immunity, Innate', 'Oxidative Stress', 'Penaeidae', 'Stress, Physiological', 'Transcriptome'] | 30,205,201 | [['D01.362.075', 'D01.625.050'], ['B01.050'], ['G04.146.954.035'], ['D12.776.093'], ['D27.888.284'], ['E05.393.332'], ['A13.463'], ['G12.450.564'], ['G03.673', 'G07.775.750'], ['B01.050.500.131.365.190.660'], ['G07.775'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Towards an in vivo morphologic classification of melanocytic nevi. | BACKGROUND: Nevi are common benign neoplasms and the main diagnostic entity in the differential diagnosis of melanoma. Reflectance confocal microscopy (RCM), a novel technique for skin imaging at cellular-level magnification, has been shown to be useful for differentiating nevi from melanoma. However, systematic studie... | ['Biopsy', 'Cell Proliferation', 'Humans', 'Melanocytes', 'Melanoma', 'Microscopy, Confocal', 'Nevus, Pigmented', 'Risk Factors', 'Skin Neoplasms'] | 23,659,610 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.750', 'A11.436.613'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
DNA Damage in Bone Marrow Cells Induced by Femtosecond and Nanosecond Ultraviolet Laser Pulses. | OBJECTIVE: The purpose of this study was to investigate the possible genotoxic impact of new generation 205 nm femtosecond solid-state laser irradiation on the DNA of murine bone marrow cells in vitro, and to compare the DNA damage caused by both femtosecond and nanosecond UV laser pulses.BACKGROUND DATA: Recent experi... | ['Animals', 'Bone Marrow Cells', 'DNA Damage', 'Lasers', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Ultraviolet Rays'] | 26,587,677 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G05.200'], ['E07.632.490', 'E07.710.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.57... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Babesiosis caused by a large Babesia species in 7 immunocompromised dogs. | BACKGROUND: A large unnamed Babesia species was detected in a dog with lymphoma. It was unknown if this was an underrecognized pathogen.OBJECTIVE: Report the historical and clinicopathologic findings in 7 dogs with babesiosis caused by a large unnamed Babesia species characterize the 18S ribosomal ribonucleic acid (rRN... | ['Animals', 'Babesia', 'Babesiosis', 'DNA, Protozoan', 'Dog Diseases', 'Dogs', 'Immunocompromised Host', 'RNA, Ribosomal, 18S', 'Retrospective Studies'] | 20,002,547 | [['B01.050'], ['B01.043.075.600.580.070'], ['C01.610.701.688.122', 'C01.610.752.075', 'C01.610.752.625.122', 'C01.920.930.182', 'C22.674.710.122'], ['D13.444.308.442'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['G12.470'], ['D13.444.735.686.675'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', ... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An assessment of institutional review committees in human experimentation. | A study of the functioning of an institutional review committee, when combined with the Barber et al. survey data on 300 institutions, allows for a useful provisional assessment of the strengths and weaknesses of existing procedures for protecting human research subjects. The evidence shows that there is an important r... | ['Clinical Trials as Topic', 'Cooperative Behavior', 'Drug Evaluation', 'Ethical Review', 'Ethics Committees, Research', 'Ethics, Medical', 'Evaluation Studies as Topic', 'Female', 'Hospitals, University', 'Human Experimentation', 'Humans', 'Informed Consent', 'Oxytocics', 'Pregnancy', 'Professional Staff Committees', ... | 1,091,788 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F01.145.813.115'], ['E05.290.625', 'E05.337.425'], ['K01.752.566.479.117', 'N05.350.250'], ['K01.752.566.479.147.750', 'N04.452.758.788.300.750', 'N05.350.268.750', 'N05.700.685.300.750'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Na... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Mothers' feelings about breastfeeding their premature babies in a rooming-in facility. | This study aimed at learning about the feelings experienced by mothers while breastfeeding their premature babies in a rooming-in facility, by means of individual interviews with 33 mothers during the period of February to April 2006, at a maternity hospital in Natal/RN/Brazil. The main feelings referred by the mothers... | ['Adolescent', 'Breast Feeding', 'Emotions', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Mothers', 'Rooming-in Care', 'Young Adult'] | 20,961,034 | [['M01.060.057'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['N02.421.088.120.240'], ['M0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Successful resection of a congenital superior mesenteric arteriovenous malformation. | A 15-month-old male presented with severe gastrointestinal bleeding and heart failure. Imaging revealed a superior mesenteric artery arteriovenous malformation, associated with a congenital portosystemic shunt. The heart failure was cured by resection of the arteriovenous malformation. | ['Arteriovenous Malformations', 'Cardiac Output, High', 'Gastrointestinal Hemorrhage', 'Humans', 'Infant', 'Male', 'Mesenteric Artery, Superior', 'Radiography'] | 17,160,783 | [['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['C14.280.142', 'C23.888.176'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A07.015.114.565.755'], ['E01.370.350.700']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Does hepatic vagus nerve modulate the progression of biliary fibrosis in rats? | Recent studies have shown that vagus nerve activation inhibits cytokine production in a variety of non-neural cells though activation of á7 nicotinic acetylcholine receptor (á7nAChR). Since chronic inflammation plays a pivotal role in liver fibrosis, this study was designed to investigate the role of hepatic vagus nerv... | ['Aconitine', 'Animals', 'Aspartate Aminotransferases', 'Chemokine CCL2', 'Disease Models, Animal', 'Disease Progression', 'Epithelium', 'Hepatocytes', 'Liver', 'Liver Cirrhosis, Biliary', 'Male', 'Myofibroblasts', 'Nicotinic Antagonists', 'RNA, Messenger', 'Rats, Sprague-Dawley', 'Tissue Inhibitor of Metalloproteinase... | 25,088,816 | [['D02.455.849.291.184.037', 'D03.132.301.030'], ['B01.050'], ['D08.811.913.477.700.225'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.656'], ['A1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The physical activity and nutrition-related corporate social responsibility initiatives of food and beverage companies in Canada and implications for public health. | BACKGROUND: As diet-related diseases have increased over the past decades, large food companies have come under scrutiny for contributing to this public health crisis. In response, the food industry has implemented Corporate Social Responsibility (CSR) initiatives related to nutrition and physical activity to emphasize... | ['Advertising', 'Beverages', 'Canada', 'Child', 'Cross-Sectional Studies', 'Diet', 'Education', 'Exercise', 'Food', 'Food Industry', 'Gift Giving', 'Humans', 'Marketing', 'Public Health', 'Public Relations', 'Research', 'Social Responsibility'] | 32,517,669 | [['J01.219.687.274', 'L01.143.050'], ['G07.203.100', 'J02.200'], ['Z01.107.567.176'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['I02'], ['G11.427.410.698.277', 'I03.350'], ['G07.203.300', 'J02.500'], ['J01.576.423'], ['F01.145.813.208'], ['B01.... | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psyc... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Freezing-thawing and sub-sampling influence the marination performance of chicken breast meat. | Vacuum-tumbling marination is often used to improve the yield and quality of whole or portioned broiler breast fillets. The relationship between the marination performance of whole Pectoralis major muscles and breast fillet sub-samples is not well understood. The objective was to determine the effects of sub-sampling a... | ['Animals', 'Chickens', 'Food Handling', 'Freezing', 'Meat', 'Pectoralis Muscles', 'Vacuum'] | 28,854,744 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['J01.576.423.200'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['G07.203.300.600', 'J02.500.600'], ['A02.633.567.775'], ['G01.374.715.902', 'G16.500.750.274.902', 'N06.230.300.100.185.902']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Theoretical modelling of some spatial and temporal aspects of the mitochondrion/creatine kinase/myofibril system in muscle. | After discussing approaches to the modelling of mitochondrial regulation in muscle, we describe a model that takes account, in a simplified way, of some aspects of the metabolic and physical structure of the energy production/usage system. In this model, high-energy phosphates (ATP and phosphocreatine) and low energy m... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Aerobiosis', 'Creatine', 'Creatine Kinase', 'Cytosol', 'Diffusion', 'Energy Metabolism', 'Kinetics', 'Mitochondria', 'Models, Biological', 'Muscle, Skeletal', 'Myofibrils', 'Myosins', 'Phosphocreatine', 'Thermodynamics'] | 9,746,325 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.017', 'G03.049'], ['D02.078.370.280', 'D12.125.373'], ['D08.811.913.696.640.150'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors influencing the pursuit of careers in academic medicine: a survey of MD-PhD residents in dermatology programs in the United States. | A survey of all MD-PhD residents in dermatology in the United States was conducted to evaluate the factors important to them in making career pathway decisions. Twenty-six MD-PhDs responded to the survey representing a 90% response rate. Although essentially all entered dermatology with the intention of pursuing a care... | ['Academic Medical Centers', 'Adult', 'Career Choice', 'Dermatology', 'Education, Medical, Graduate', 'Female', 'Humans', 'Internship and Residency', 'Male', 'Research', 'Surveys and Questionnaires', 'United States'] | 1,732,378 | [['N02.278.020'], ['M01.060.116'], ['F02.463.785.373.346.400'], ['H02.403.225'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['H01.770.644'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.107.567.875'... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Toward a study of gene regulatory constraints to morphological evolution of the Drosophila ocellar region. | The morphology and function of organs depend on coordinated changes in gene expression during development. These changes are controlled by transcription factors, signaling pathways, and their regulatory interactions, which are represented by gene regulatory networks (GRNs). Therefore, the structure of an organ GRN rest... | ['Animals', 'Bayes Theorem', 'Drosophila', 'Drosophila Proteins', 'Evolution, Molecular', 'Gene Regulatory Networks', 'Genetic Variation', 'Hedgehog Proteins', 'Machine Learning'] | 27,038,024 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G05.045.250', 'G16.075.250'], ['G05.360.080.689.360'], ['G05.365'], ['D12.644.276.671', 'D12.776.467.671', 'D23.529.671'], ['G17.035.250.500', 'L01.224... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Induction of cytoplasmic factors that bind to the 3' AU-rich region of human interferon beta mRNA during early development of Xenopus laevis. | Certain endogenous Xenopus mRNAs, carrying a destabilizing 3' AU-rich sequence, are unusually very stable in oocytes and become unstable only after fertilization. In addition, heterologous short lived mRNA, containing 3' AU-rich sequences, appear to be very stable when injected into Xenopus oocytes. In the present stud... | ['Adenine', 'Animals', 'Binding Sites', 'Blastocyst', 'Cell Line', 'Cytoplasm', 'Egg Proteins', 'Embryo, Nonmammalian', 'Female', 'Fertilization', 'Humans', 'Interferon-beta', 'Morula', 'Oocytes', 'Ovum', 'Protein Binding', 'RNA, Messenger', 'RNA-Binding Proteins', 'Uracil', 'Xenopus laevis'] | 8,282,101 | [['D03.633.100.759.138'], ['B01.050'], ['G02.111.570.120'], ['A16.254.500'], ['A11.251.210'], ['A11.284.430.214'], ['D12.776.290'], ['A13.350', 'A16.331'], ['G08.686.784.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.275', 'D12.776.467.374.440.890.275', 'D23.529.374.440.890.275'], ['A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Spoligotypes of Mycobacterium tuberculosis in the Czech population (methods and pilot study)]. | In the introduction the authors describe molecular genetic principles of spacer oligonucleotide typing of the M. tuberculosis complex and mention in detail the methodical procedure of implementation of this examination technique incl. computer analysis of results. In the pilot part of the study the authors describe exa... | ['Bacterial Typing Techniques', 'Czech Republic', 'DNA, Bacterial', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mycobacterium tuberculosis', 'Oligonucleotides', 'Tuberculosis'] | 11,987,580 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['Z01.542.248.395'], ['D13.444.308.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D13.695.578.424'], ['C01.150.252.410.040.552.846']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Kinetic stability of designed glycosylation mutants of Coprinus cinereus peroxidase. | The effect of glycans and surface mutations on protein unfolding induced by heat or urea has been studied. Removal of the only native high mannose type glycan in the N142P, N142T, and N142D CIP mutants reduced the lifetime to half of that of wtCIP at irreversible conditions of unfolding. The effect was moderate at reve... | ['Binding Sites', 'Coprinus', 'Enzyme Stability', 'Fungal Proteins', 'Glycoproteins', 'Glycosylation', 'Heme', 'Kinetics', 'Mutation', 'Peroxidases', 'Polysaccharides', 'Protein Folding', 'Temperature'] | 11,520,054 | [['G02.111.570.120'], ['B01.300.179.100.200'], ['E05.916.360', 'G02.111.700.500'], ['D12.776.354'], ['D09.400.430', 'D12.776.395'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['G01.374.661', 'G0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dynamic regulation of CD45 lateral mobility by the spectrin-ankyrin cytoskeleton of T cells. | The leukocyte common antigen, CD45, is a critical immune regulator whose activity is modulated by cytoskeletal interactions. Components of the spectrin-ankyrin cytoskeleton have been implicated in the trafficking and signaling of CD45. We have examined the lateral mobility of CD45 in resting and activated T lymphocytes... | ['Ankyrins', 'Cytoskeleton', 'Diffusion', 'Humans', 'Jurkat Cells', 'Leukocyte Common Antigens', 'Markov Chains', 'Microscopy, Fluorescence', 'Microspheres', 'Models, Biological', 'Models, Molecular', 'Molecular Conformation', 'Protein Structure, Tertiary', 'Spectrin', 'T-Lymphocytes'] | 20,164,196 | [['D12.776.543.080'], ['A11.284.430.214.190.750'], ['G01.202', 'G02.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'], ['D08.811.277.352.650.775.400.100.500', 'D12.644.360.587.100.500', 'D12.776.476.592.100.500', 'D12.776.543.733.937.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Heat production as a criterion of adrenergic regulation of metabolic processes of the myocardium]. | Bolus injection of adrenaline in coronary perfusion blood flow caused different-directed changes in coronary venous blood temperature. Directivity and myocardium heat production changes are determined by peculiarities of interactions between adrenergic and cholinergic mechanisms of cardiodynamics and myocardial metabol... | ['Animals', 'Body Temperature Regulation', 'Coronary Circulation', 'Dogs', 'Energy Metabolism', 'Epinephrine', 'Heart', 'Myocardial Contraction', 'Myocardium', 'Receptors, Adrenergic'] | 2,591,579 | [['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['G03.295'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['A07.541'], ['G09.330.580', 'G11.427.494.570']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical laparoscopy in the management of women infertility]. | The authors report their experience about surgical laparoscopy in the management of women infertility. Based on a series of 87 patients (median age: 31 years), 61% have primary infertility. The surgical procedures were distal tuboplasty in 26 cases, endometriosis cure in 19 cases, ovarian driling for polycystic ovarian... | ['Adult', 'Endometriosis', 'Female', 'Follow-Up Studies', 'Humans', 'Infant, Newborn', 'Infertility, Female', 'Laparoscopy', 'Ovarian Diseases', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Pregnancy, Ectopic', 'Salpingostomy', 'Time Factors', 'Tissue Adhesions'] | 15,693,477 | [['M01.060.116'], ['C13.351.500.163'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C13.351.500.365.700'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C13.351.500.056.630', 'C19.391.630'], ['C04.182.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long noncoding RNA TALNEC2 plays an oncogenic role in breast cancer by binding to EZH2 to target p57KIP2 | We aimed to investigate the potential role and regulatory mechanism of long noncoding RNA tumor-associated lncRNA expressed in chromosome 2 (TALNEC2) in breast cancer. The expression of TALNEC2 in breast cancer tissues and cells were investigated. MCF-7 and MDA-MB-231 cells were transfected with small interfering RNA (... | ['Apoptosis', 'Autophagy', 'Breast Neoplasms', 'Cell Proliferation', 'Cyclin-Dependent Kinase Inhibitor p57', 'Enhancer of Zeste Homolog 2 Protein', 'Female', 'Humans', 'MCF-7 Cells', 'NF-kappa B', 'Protein Binding', 'RNA, Long Noncoding', 'Signal Transduction', 'p38 Mitogen-Activated Protein Kinases'] | 30,378,143 | [['G04.146.954.035'], ['G04.011'], ['C04.588.180', 'C17.800.090.500'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.360.225.700', 'D12.776.167.187.700', 'D12.776.476.225.700', 'D12.776.624.776.355.700'], ['D05.500.781.750.250', 'D08.811.913.555.500.800.200.500.500.500', 'D12.776.660.235.600.200.250', 'D12.776.664.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
From medical gaze to statistical person: Historical reflections on evidence-based and personalised medicine. | BACKGROUND: The nineteenth century saw the rise of what historians of medicine have termed the 'medical gaze'. Physicians used instrumentation and trained senses to locate the site of disease within the patient's body. This change in practice went alongside changes in the physician's power and how diseases were underst... | ['Economics', 'Evidence-Based Medicine', 'History, 19th Century', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Politics', 'Precision Medicine', 'Social Change'] | 27,606,362 | [['I01.261', 'N03.219'], ['H02.249.750', 'H02.403.200.400'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.738'], ['E02.782', 'H02.403.200.700'], ['I01.076.201.450.776', 'I01.880.853.400', 'N01.824.737']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Ethyl glucuronide in keratinous matrices as biomarker of alcohol use: A correlation study between hair and nails. | To quantify alcohol use, objective, specific and sensitive long-term alcohol markers are necessary. Ethyl glucuronide (EtG), a direct metabolite of alcohol, accumulates in keratinous matrices such as hair and nails, and is a specific and sensitive long-term biomarker for the detection of chronic alcohol consumption. So... | ['Adolescent', 'Adult', 'Aged', 'Alcohol Abstinence', 'Alcohol Drinking', 'Alcoholism', 'Biomarkers', 'Chromatography, Gas', 'Female', 'Forensic Toxicology', 'Glucuronates', 'Hair', 'Humans', 'Male', 'Middle Aged', 'Nails', 'Reference Values', 'Tandem Mass Spectrometry', 'Young Adult'] | 28,892,761 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.317.134'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['D23.101'], ['E05.196.181.349'], ['H01.158.891.424', 'H02.884.424', 'I01.198.780.968'], ['D02.241.081.844.915.162', 'D02.241.152.811.162', 'D02.241.511.902.915.162', 'D09.811.922.16... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Size dictates mechanical properties for protein fibers self-assembled by the Drosophila hox transcription factor ultrabithorax. | The development of protein-based materials with diverse mechanical properties will facilitate the realization of a broad range of potential applications. The recombinant Drosophila melanogaster transcription factor Ultrabithorax self-assembles under mild conditions in aqueous buffers into extremely extensible materials... | ['Animals', 'Biocompatible Materials', 'Drosophila Proteins', 'Drosophila melanogaster', 'Homeodomain Proteins', 'Materials Testing', 'Mechanical Phenomena', 'Proteins', 'Transcription Factors'] | 21,047,055 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D12.776.260.400'], ['E05.570'], ['G01.374'], ['D12.776'], ['D12.776.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
LC-MS-MS for the determination of ponicidin in dog plasma. | A highly specific and sensitive liquid chromatography-tandem mass spectrometry method has been developed and validated for the determination of ponicidin in dog plasma. The plasma samples were prepared using liquid-liquid extraction with ethyl acetate as the extraction solvent. Chromatographic separation was accomplish... | ['Animals', 'Chromatography, Liquid', 'Diterpenes', 'Dogs', 'Female', 'Linear Models', 'Male', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tandem Mass Spectrometry'] | 23,505,290 | [['B01.050'], ['E05.196.181.400'], ['D02.455.849.291'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.318.370.725', 'E05.337.851', 'N05.715.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment. | Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenosine and ATP. Physiological significance of this biochemical feature is unknown, but it has been suggested that it may affect infiltrating immune cell responses and tumor progression. There is increasing awareness that ma... | ['Adenosine Triphosphate', 'Animals', 'Arginase', 'Biomarkers, Tumor', 'CD11b Antigen', 'Cell Line, Tumor', 'Cytokines', 'Female', 'HEK293 Cells', 'Humans', 'Mice', 'Myeloid Cells', 'Neuroblastoma', 'Reactive Oxygen Species', 'Receptors, Chemokine', 'Receptors, Purinergic P2X7', 'Signal Transduction', 'Transfection', '... | 24,651,438 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.277.913.292'], ['D23.101.140'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.776.543.750.705.408.100.150', 'D12.776.543.750.705.833.062', 'D23.050.301.350.074.049'], ['A11.251.210.190', 'A11.251... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-management strategies to support performance of daily activities in hand osteoarthritis. | AIMS: The main aim of this study was to explore self-management strategies in persons with hand osteoarthritis (HOA).METHODS: Self-management strategies were explored in semi-structured interviews, in which 125 participants described strategies, use of devices or equipment, and advice they would give to people with HOA... | ['Activities of Daily Living', 'Aged', 'Attitude to Health', 'Disabled Persons', 'Female', 'Hand Joints', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Occupational Therapy', 'Osteoarthritis', 'Self Care', 'Self-Help Devices', 'Sweden'] | 22,376,127 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['M01.150'], ['A02.835.583.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Diseases [C]', '... | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Fenofibrate increases serum creatinine in a patient with familial nephropathy associated to hyperuricemia. | BACKGROUND: Kidney function progressively deteriorates in patients with familial juvenile hyperuricemiac nephropathy (FJHN, OMIN 162000) and chronic renal disease is commonly associated to dyslipidemia. We report for the first time abrupt renal insufficiency in a patient with FJHN and hypertrygliceridemia following fen... | ['Adult', 'Creatinine', 'Female', 'Fenofibrate', 'Gout', 'Humans', 'Hypertriglyceridemia', 'Hyperuricemia', 'Kidney', 'Kidney Diseases', 'Male', 'Middle Aged', 'Withholding Treatment', 'Young Adult'] | 24,940,667 | [['M01.060.116'], ['D03.383.129.308.207'], ['D02.241.081.114.968.500.625', 'D02.355.726.305.625', 'D02.455.426.559.389.134.750', 'D02.455.426.559.389.657.654.305.625', 'D02.522.223.750'], ['C05.550.114.423', 'C05.550.354.500', 'C05.799.414', 'C16.320.565.798.368', 'C18.452.648.798.368'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Probabilistic estimation of residential air exchange rates for population-based human exposure modeling. | Residential air exchange rates (AERs) are a key determinant in the infiltration of ambient air pollution indoors. Population-based human exposure models using probabilistic approaches to estimate personal exposure to air pollutants have relied on input distributions from AER measurements. An algorithm for probabilistic... | ['Air Pollutants', 'Air Pollution', 'Air Pollution, Indoor', 'Algorithms', 'Censuses', 'Cities', 'Environmental Exposure', 'Environmental Monitoring', 'Housing', 'Humans', 'Poverty', 'Probability', 'Seasons', 'United States', 'Wind'] | 27,553,990 | [['D27.888.284.101'], ['N06.850.460.100'], ['N06.850.460.100.080'], ['G17.035', 'L01.224.050'], ['I01.240.205', 'N01.224.175', 'N06.850.505.400.225'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.85... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E... | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
A novel salt-induced gene from sheepgrass, LcSAIN2, enhances salt tolerance in transgenic Arabidopsis. | Salt stress affects plant growth and development, and limits the productivity of crops. Sheepgrass can grow well under various environmental and soil conditions and is a good wild resource in Triticeae. Using 454 high throughout sequencing technique, a large number of salt stress responsive genes have been picked out f... | ['Amino Acid Sequence', 'Arabidopsis', 'Cell Nucleus', 'Cloning, Molecular', 'Computational Biology', 'Gene Expression', 'Genes, Plant', 'Membrane Proteins', 'Molecular Sequence Data', 'Molecular Structure', 'Nuclear Proteins', 'Plant Leaves', 'Plant Proteins', 'Plants, Genetically Modified', 'Poaceae', 'Promoter Regio... | 23,353,766 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.393.220'], ['H01.158.273.180', 'L01.313.124'], ['G05.297'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D12.776.543'], ['L01.453.245.667'], ['G02.111.570', 'G02.466']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Control of the red tide dinoflagellate Cochlodinium polykrikoides by ozone in seawater. | The inactivation of C. polykrikoides, a red tide dinoflagellate, by ozonation was investigated in seawater by monitoring numbers of viable and total cells. Parameters affecting the inactivation efficacy of C. polykrikoides such as the ozone dose, initial cell concentration, pH, and temperature were examined. The viable... | ['Dinoflagellida', 'Harmful Algal Bloom', 'Ozone', 'Seawater', 'Temperature'] | 27,907,823 | [['B01.043.214'], ['G16.500.285.400'], ['D01.362.670.600'], ['G16.500.275.725.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
C/EBPá inhibits proliferation of breast cancer cells via a novel pathway of miR-134/CREB. | C/EBPá plays an important role in the modulation of cell proliferation, differentiation or apoptosis in various tissues. Most recently, reduced expression of C/EBPá and growth inhibitory effect was found in primary mammary carcinomas. However, the underlying mechanism is still not fully aware. Here, we firstly identifi... | ['Apoptosis', 'Breast Neoplasms', 'CCAAT-Enhancer-Binding Proteins', 'Cell Proliferation', 'Cyclic AMP Response Element-Binding Protein', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MCF-7 Cells', 'MicroRNAs', 'Proto-Oncogene Proteins c-bcl-2', 'Signal Transduction', 'Time Factors', 'Transfection'] | 26,823,765 | [['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630'], ['D13.150.650.31... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Specialist-centred model of care using oncology as example]. | During the last ten years the management of oncological patients has been shifted almost entirely from the inpatient to an outpatient setting, but without increasing the financial budget for ambulatory medical care. This is why new contracts should be established according to Sect. 140 et seqq, especially if the number... | ['Germany', 'Humans', 'Medical Oncology', 'Medicine', 'Neoplasms', 'Quality Assurance, Health Care', 'Specialization'] | 16,524,226 | [['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['H02.403'], ['C04'], ['N04.761.700', 'N05.700'], ['H02.811']] | ['Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Correlation between calcium carbonate content and emission characteristics of incense. | In Taiwan and China, calcium carbonate is commonly added as a filler during incense production to lower the cost. This study has found an unexpected benefit for this practice: it reduces particulate emission. Nine types of the popular incense on the local market were chosen for this study. The calcium content in raw ma... | ['Air Pollution, Indoor', 'Calcium', 'Calcium Carbonate', 'China', 'Humans', 'Particulate Matter', 'Polycyclic Aromatic Hydrocarbons', 'Smoke', 'Spectrometry, X-Ray Emission', 'Spectrophotometry, Atomic', 'Taiwan'] | 17,195,491 | [['N06.850.460.100.080'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.633'], ['D02.455.426.559.847', 'D04.615'], ['D20.633.937'], ['E05.196.867.800', 'E05.799.830'], ['E05.196.71... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Production, milk iodine, and nutrient utilization in Jersey cows supplemented with the brown seaweed Ascophyllum nodosum (kelp meal) during the grazing season. | Kelp meal (KM) is a supplement made from the brown seaweed Ascophyllum nodosum, known to bioaccumulate iodine (I) and to be the richest source of phlorotannins, which can inhibit ruminal proteolysis and microbial growth. The objective of this study was to investigate the effects of KM on production, milk I, concentrati... | ['Animal Feed', 'Animals', 'Ascophyllum', 'Cattle', 'Dairying', 'Diet', 'Dietary Fiber', 'Dietary Supplements', 'Digestion', 'Fatty Acids', 'Female', 'Iodine', 'Kelp', 'Lactation', 'Milk', 'Nutrients', 'Random Allocation'] | 31,279,546 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.750.600.040'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['G07.203.650.240'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.650.250', 'G10.261.190'], ['D10.251'], ['D01.268.380.400'], ['B01... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Comparison of the clinical efficacy between tigecycline plus extended-infusion imipenem and sulbactam plus imipenem against ventilator-associated pneumonia with pneumonic extensively drug-resistant Acinetobacter baumannii bacteremia, and correlation of clinical efficacy with in vitro synergy tests. | BACKGROUND/PURPOSE: To compare the clinical efficacy between salvage antimicrobial regimen consisting of tigecycline plus extended-infusion imipenem/cilastatin (TIC) and regimen of sulbactam plus imipenem/cilastatin (SIC) for patients with ventilator-associated pneumonia and pneumonic bacteremia due to extensively drug... | ['Acinetobacter Infections', 'Acinetobacter baumannii', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Bacteremia', 'Cilastatin', 'Cilastatin, Imipenem Drug Combination', 'Drug Combinations', 'Drug Resistance, Multiple, Bacterial', 'Drug Synergism', 'Drug Therapy, Combination', 'Female', 'Hospital Mort... | 26,341,302 | [['C01.150.252.400.560.022'], ['B03.440.400.425.537.050.099', 'B03.660.250.530.050.099'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['D02.455.426.392.368.533.200', 'D10.251.355.325.200'], ['D02.065.589.099.124.3... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Aborted genital herpes simplex virus lesions: findings from a randomised controlled trial with valaciclovir. | OBJECTIVES: In prospective trials, episodic valaciclovir significantly increased the chance of preventing or aborting the development of painful vesicular genital herpes simplex virus (HSV) lesions compared with placebo. We explored the clinical outcome of aborted lesions and its association with early treatment in a s... | ['Acyclovir', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antiviral Agents', 'Double-Blind Method', 'Female', 'Herpes Genitalis', 'Herpesvirus 2, Human', 'Humans', 'Male', 'Middle Aged', 'Prodrugs', 'Treatment Outcome', 'Valacyclovir', 'Valine'] | 12,473,805 | [['D03.633.100.759.758.399.454.250'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.388'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C01.221.812.640.350', 'C01.778.640.350', 'C01.925.256.466.382.290', 'C01.925.813.350', 'C... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Could ZI have a role in DBS for Parkinson's Disease? An observational study to optimize DBS target localization. | Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is a well-recognized intervention for Parkinson's Disease (PD). We used LEAD-DBS, a toolbox facilitating DBS electrode reconstructions and computer simulations based on postoperative MRI and CT imaging, to investigate the interaction and followed benefits of... | ['Aged', 'Deep Brain Stimulation', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Parkinson Disease', 'Postoperative Period', 'Retrospective Studies', 'Subthalamic Nucleus', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Zona Incerta'] | 32,402,608 | [['M01.060.116.100'], ['E02.331.300', 'E04.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['E04.614.750', 'N02.421.585.753.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pathogenesis of experimental lipid keratopathy. An ultrastructural study of an animal model system. | The histology and ultrastructure of experimental lipid keratopathy were studied in hypercholesterolemic rabbits in which the insertion of corneal sutures induced vascularization and subsequent lipid deposition in the anterior stroma. Lipid accumulated in the keratocytes, the pericytes and occasionally in the endothelia... | ['Animals', 'Cornea', 'Corneal Diseases', 'Corneal Stroma', 'Disease Models, Animal', 'Lipid Metabolism', 'Microscopy, Electron', 'Rabbits'] | 3,170,126 | [['B01.050'], ['A09.371.060.217'], ['C11.204'], ['A09.371.060.217.228'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G03.458'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A section press and low elemental support for enhanced preparation of freeze-dried cryosections. | A press- and specimen holder system is described, whereby thin, freeze-dried cryosections can be obtained more conveniently and with greater protection against contamination and harmful temperature fluctuations. The use of a grid and retainer assembly as the basic working unit, greatly facilitates low temperature work ... | ['Animals', 'Freeze Drying', 'Humans', 'Rats', 'Specimen Handling'] | 6,716,461 | [['B01.050'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E05.200.750.600.760.160.260', 'E05.760.156.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['E01.370.225.998', 'E05.200.998']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteasomal degradation of T. gondii ROP18 requires Derlin2. | T. gondii is an obligate intracellular parasite, belonging to the Phylum Apicomplexa, infecting all warm-blooded animals including humans. During host cell invasion, specialized cytoskeletal and secretory organelles play a pivotal role. ROP18, as a member of the ROP2 family, has been identified as a key virulence facto... | ['Animals', 'Humans', 'Protein-Serine-Threonine Kinases', 'Proteolysis', 'Toxoplasma', 'Virulence Factors'] | 28,669,563 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700'], ['G02.111.720', 'G03.812'], ['B01.043.075.189.250.750.800'], ['D23.946.896']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of ribosomal RNA in human fibroblasts continuously treated with hydrocortisone. | The prolongation of the limited lifespan of human embryonic lung fibroblasts by hydrocortisone was previously associated with increased uridine incorporation into ribosomal RNA (rRNA). Using polyacrylamide gel electrophoresis, we show here that the continuous treatment with 12 microM hydrocortisone results in increased... | ['Blood', 'Cell Division', 'Cell Line', 'Culture Media', 'Fibroblasts', 'Humans', 'Hydrocortisone', 'Interphase', 'Lung', 'Nucleic Acid Precursors', 'RNA', 'RNA Precursors', 'RNA, Ribosomal'] | 6,193,981 | [['A12.207.152', 'A15.145'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D27.720.470.305', 'E07.206'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['G04.144.500']... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical outcome of catheter fragmentation and aspiration therapy in patients with acute pulmonary embolism]. | The clinical usefulness of catheter fragmentation and aspiration therapy was studied in 8 patients with acute pulmonary embolism who received thrombolytic therapy using urokinase or tissue-type plasminogen activator (t-PA) (thrombolysis group) and 8 patients who underwent catheter fragmentation and aspiration therapy u... | ['Acute Disease', 'Adult', 'Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Embolism', 'Suction', 'Tissue Plasminogen Activator', 'Treatment Outcome'] | 10,466,088 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['B01.050.150.900.649.313.988.400... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Value of CT imaging in the differentiation of gastric leiomyomas from gastric stromal tumors]. | Objective: To explore the application value of CT imaging in differentiating gastric stromal tumors (GST) from gastric leiomyomas (GLMs). Methods: CT images of patients with GST (n=65) or GLMs (n=13, maximum diameter of tumor ?5 cm) proved by surgery and pathology were retrospectively analyzed. The tumor size, location... | ['Calcinosis', 'Diagnosis, Differential', 'Female', 'Gastrointestinal Stromal Tumors', 'Humans', 'Leiomyoma', 'Male', 'ROC Curve', 'Retrospective Studies', 'Sensitivity and Specificity', 'Stomach Neoplasms', 'Tomography, X-Ray Computed', 'Tumor Burden'] | 28,219,211 | [['C18.452.174.130'], ['E01.171'], ['C04.557.450.565.370', 'C06.301.371.308', 'C06.405.249.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects. | INTRODUCTION: Obesity is linked to type 2 diabetes and risk factors associated to the metabolic syndrome. Consumption of dietary fibres has been shown to have positive metabolic health effects, such as by increasing satiety, lowering blood glucose and cholesterol levels. These effects may be associated with short-chain... | ['Animals', 'Body Weight', 'Butyrates', 'Chemokine CCL2', 'Cholesterol', 'Colon', 'Diet', 'Diet, High-Fat', 'Dietary Fiber', 'Fatty Acids, Volatile', 'Inflammation', 'Liver', 'Male', 'Microbiota', 'Organ Size', 'Pectins', 'Rats', 'Succinic Acid', 'Time Factors'] | 24,236,183 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.241.081.114', 'D10.251.400.143'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Noradrenergic regulation of GABAergic inhibition of main olfactory bulb mitral cells varies as a function of concentration and receptor subtype. | The main olfactory bulb (MOB) receives a rich noradrenergic innervation from the pontine nucleus locus coeruleus (LC). Previous studies indicate that norepinephrine (NE) modulates the strength of GABAergic inhibition in MOB. However, the nature of this modulation and the NE receptors involved remain controversial. The ... | ['Adrenergic Agonists', 'Adrenergic Antagonists', 'Analysis of Variance', 'Animals', 'Animals, Newborn', 'Dose-Response Relationship, Drug', 'Excitatory Amino Acid Antagonists', 'Female', 'GABA Modulators', 'In Vitro Techniques', 'Inhibitory Concentration 50', 'Inhibitory Postsynaptic Potentials', 'Male', 'Neural Inhib... | 19,279,145 | [['D27.505.519.625.050.100', 'D27.505.696.577.050.100'], ['D27.505.519.625.050.200', 'D27.505.696.577.050.200'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.050.282'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['D27.505.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Back to the Future - in support of a renewed emphasis on generic agility training within sports-specific developmental pathways. | Perhaps as a consequence of increased specialism in training and support, the focus on engendering and maintaining agility as a generic quality has diminished within many contemporary sports performance programmes. Reflecting this, we outline a rationale suggesting that such a decreased focus represents an oversight wh... | ['Adult', 'Athletic Injuries', 'Athletic Performance', 'Cumulative Trauma Disorders', 'Humans', 'Motor Skills', 'Physical Conditioning, Human', 'Physical Education and Training', 'Specialization'] | 29,521,175 | [['M01.060.116'], ['C26.115'], ['I03.450.642.845.054'], ['C26.844.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808.260'], ['G11.427.410.698.277.311', 'I03.350.311'], ['I02.233.543'], ['H02.811']] | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
The GORE TAG conformable thoracic stent graft with the new ACTIVE CONTROL deployment system. | OBJECTIVE: The aim of this study was to describe single-center intraoperative details and early outcome of the new GORE TAG conformable stent graft with ACTIVE CONTROL (C-TAG ACTIVE CONTROL; W. L. Gore & Associates, Flagstaff, Ariz).METHODS: Between September 2017 and June 2018, a consecutive 30 patients underwent thor... | ['Aged', 'Aorta, Thoracic', 'Aortic Diseases', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Endovascular Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prosthesis Design', 'Retrospective Studies', 'Risk Factors', 'Stents', 'Time Factors', 'Treatment Outcom... | 30,922,741 | [['M01.060.116.100'], ['A07.015.114.056.372'], ['C14.907.109'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.320.550', 'E07.695.680'], ['E05.318.372.500.500.500', 'E05.318.372.500... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of exercise on body weight and circulating leptin in premature infants. | OBJECTIVE: To assess the effect of daily movements on weight gain, serum leptin, and insulin-like growth factor I (IGF-I) in premature infants.STUDY DESIGN: Twenty very-low-birth-weight premature infants were matched and randomized to a daily movement (n = 10) and control groups (n = 10). Daily movement consisted of pa... | ['Bone Density', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Infant, Very Low Birth Weight', 'Insulin-Like Growth Factor I', 'Leptin', 'Male', 'Movement', 'Weight Gain'] | 12,368,971 | [['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['M01.060.703.520.460.600'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.5... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Medulloblastoma in a child with the metabolic disease L-2-hydroxyglutaric aciduria. | L-2-Hydroxyglutaric aciduria (LHGA) is a rare autosomal recessively inherited neurodegenerative disorder. It is characterized by psychomotor retardation, progressive ataxia and typical magnetic resonance imaging findings, and presents in early infancy. On the other hand, medulloblastomas are very common solid tumors of... | ['Brain Diseases, Metabolic, Inborn', 'Cerebellar Neoplasms', 'Child, Preschool', 'Humans', 'Hydroxy Acids', 'Male', 'Medulloblastoma'] | 12,138,215 | [['C10.228.140.163.100', 'C16.320.565.189', 'C18.452.132.100', 'C18.452.648.189'], ['C04.588.614.250.195.411.211', 'C10.228.140.211.500.200', 'C10.228.140.252.200', 'C10.551.240.250.400.300'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511'], ['C04.557.465.625.600.380.515', 'C04.557... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lessons from early Medicaid expansions under health reform: interviews with Medicaid officials. | BACKGROUND: The Affordable Care Act (ACA) dramatically expands Medicaid in 2014 in participating states. Meanwhile, six states have already expanded Medicaid since 2010 to some or all of the low-income adults targeted under health reform. We undertook an in-depth exploration of these six "early-expander" states-Califor... | ['Health Care Reform', 'Humans', 'Interviews as Topic', 'Medicaid', 'Patient Protection and Affordable Care Act', 'Politics', 'Program Development', 'Qualitative Research', 'State Government', 'United States'] | 24,834,369 | [['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N03.219.521.346.506.564.655', 'N03.706.615.693... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Loss of myeloid related protein-8/14 exacerbates cardiac allograft rejection. | BACKGROUND: The calcium-binding proteins myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) form MRP-8/14 heterodimers (S100A8/A9, calprotectin) that regulate myeloid cell function and inflammatory responses and serve as early serum markers for monitoring acute allograft rejection. Despite functioning as a pr... | ['Animals', 'B7 Antigens', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Calgranulin A', 'Calgranulin B', 'Cytokines', 'Graft Rejection', 'Graft Survival', 'Heart Transplantation', 'Histocompatibility', 'Histocompatibility Antigens Class II', 'Leukocyte L1 Antigen Complex', 'Lymphocyte Culture Test, Mixe... | 22,144,572 | [['B01.050'], ['D12.776.467.150', 'D12.776.543.095', 'D23.050.301.285', 'D23.529.168'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D12.776.157.125.750.500.100', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lower limb trauma: primary treatment and reconstruction. | The requirements of lower limb trauma reconstruction are discussed with comment on the availability of plastic surgery services. The significance of early efficient soft tissue management is stressed and a plea is made for better cooperation between plastic and orthopaedic surgery in both training and practice. | ['Fractures, Bone', 'Humans', 'Leg Injuries', 'Orthopedics', 'Patient Care Team', 'Referral and Consultation', 'Severity of Illness Index', 'Surgery, Plastic'] | 2,589,787 | [['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['H02.403.810.494'], ['N04.590.715'], ['N04.452.758.849'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['H02.403.810.788']] | ['Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Lipid particles agglutinated in hyperlipidemias with opalescent sera (author's transl)]. | During the five last years, we observed under the microscope all the hyperlipidemic sera received in our laboratory, to search a lipid particle agglutination. We have retained 24 sera with obvious agglutination (9 types V, 9 types IV and 6 types IIb), the lipidemia of which was compared, type to type, to 56 control ser... | ['Agglutination', 'Autoimmune Diseases', 'Cholesterol', 'Hyperlipidemias', 'Lipids', 'Triglycerides'] | 372,898 | [['G02.111.026', 'G12.122.100'], ['C20.111'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C18.452.584.500.500'], ['D10'], ['D10.351.801']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vasoconstrictor-mediated release of purines and pyrimidines from perfused rat hindlimb, perfused mesenteric arcade and incubated de-endothelialized aorta. | 1. Reperfusion of hindlimbs that had previously been exposed to either 10 or 60 min global ischaemia resulted in transient washouts of uracil and uric acid in approximate proportion to the interval of ischaemia. However, changing the interval of sequential angiotensin II infusions from 10 to 60 min did not affect the m... | ['Analysis of Variance', 'Animals', 'Aorta', 'Blood Vessels', 'Chromatography, High Pressure Liquid', 'Endothelium, Vascular', 'Hindlimb', 'In Vitro Techniques', 'L-Lactate Dehydrogenase', 'Male', 'Mesenteric Artery, Superior', 'Muscle, Skeletal', 'Muscle, Smooth, Vascular', 'Perfusion', 'Rats', 'Rats, Wistar', 'Uracil... | 7,721,046 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A07.015.114.056'], ['A07.015'], ['E05.196.181.400.300'], ['A07.015.700.500', 'A10.272.491.355'], ['A13.473'], ['E05.481'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['A07.015.114.565.755'], ['A02.633.567', 'A10.690.552.500'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tokens improve capuchin performance in the reverse-reward contingency task. | In humans and apes, one of the most adaptive functions of symbols is to inhibit strong behavioural predispositions. However, to our knowledge, no study has yet investigated whether using symbols provides some advantage to non-ape primates. We aimed to trace the evolutionary roots of symbolic competence by examining whe... | ['Animals', 'Cebus', 'Choice Behavior', 'Concept Formation', 'Reward', 'Symbolism'] | 20,861,046 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.150.170.120'], ['F02.463.785.373.346'], ['F02.463.785.233'], ['F02.463.425.770.836'], ['K01.400.899', 'K01.752.798']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effectiveness of an online cognitive behavioral therapy for insomnia]. | INTRODUCTION: Insomnia is a common health problem with serious mental and physical consequences as well as increased economical costs. The use of hypnotics in Iceland is immense in spite of cognitive behavioral therapy for insomnia (CBT-I) being recommended as the first choice treatment of chronic insomnia. To meet the... | ['Adolescent', 'Adult', 'Aged', 'Cognitive Behavioral Therapy', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Internet', 'Male', 'Middle Aged', 'Patient Dropouts', 'Recovery of Function', 'Sleep', 'Sleep Initiation and Maintenance Disorders', 'Therapy, Computer-Assisted', 'Time Factors', 'Treatment Outcome', 'Young A... | 25,894,498 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['F01.100.150.750.500.610', 'F01.145.488.887.500.610', 'N05.300.150.800.500.610'], ['G16.757'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The sulphonylurea glibenclamide inhibits voltage dependent potassium currents in human atrial and ventricular myocytes. | 1 It was the aim of our study to investigate the effects of the sulphonylurea glibenclamide on voltage dependent potassium currents in human atrial myocytes. 2 The drug blocked a fraction of the quasi steady state current (ramp response) which was activated positive to -20 mV, was sensitive to 4-aminopyridine (500 micr... | ['Adenosine Triphosphate', 'Atrial Function', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Glyburide', 'Heart Atria', 'Heart Ventricles', 'Humans', 'Membrane Potentials', 'Potassium Channels', 'Time Factors', 'Ventricular Function'] | 10,578,129 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G09.330.040'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.723.402'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['A07.541.358'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.154.535', 'G04.580', 'G07.265... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Communicating the significance of radiologic test results: the likelihood ratio. | The likelihood ratio is a useful but simple concept that helps the radiologist communicate to the clinician the significance of radiologic findings. It is defined as the ratio of the probabilities of a particular test result among patients with and without disease. Readily derivable from sensitivity and specificity, th... | ['Adult', 'Bayes Theorem', 'Cholestasis', 'Colonic Neoplasms', 'Communication', 'Female', 'Humans', 'Liver Neoplasms', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pulmonary Embolism', 'Radiography', 'Radiology', 'Statistics as Topic', 'Ultrasonography'] | 3,535,461 | [['M01.060.116'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C06.130.120.135'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
The structure of erythrocyte membranes studied by freeze-etching. II. Localization of receptors for phytohemagglutinin and influenza virus to the intramembranous particles. | The distribution of specific glycoprotein receptors on the external surfaces of red cells was mapped, by the freeze-etching technique, to determine if the receptors coincided with the underlying 75-A intramembranous particles. Phytohemagglutinin, ferritin-conjugated phytohemagglutinin, and influenza virus were used as ... | ['Cell Membrane', 'Electrophoresis, Disc', 'Erythrocytes', 'Ferritins', 'Freeze Etching', 'Glycoproteins', 'Humans', 'Lectins', 'Neuraminic Acids', 'Neuraminidase', 'Orthomyxoviridae', 'Trypsin'] | 5,025,437 | [['A11.284.149'], ['E05.196.401.402.236', 'E05.301.300.319.403'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['E01.370.225.500.620.620.260.400', 'E01.370.225.750.600.620.260.400', 'E05.200.500.620.620.260.400', 'E05.200.750.600.620.260.400'], ['D09.400.430', 'D12.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of plant root morphology and tissue composition on phenanthrene uptake: stepwise multiple linear regression analysis. | Polycyclic aromatic hydrocarbons (PAHs) are contaminants that reside mainly in surface soils. Dietary intake of plant-based foods can make a major contribution to total PAH exposure. Little information is available on the relationship between root morphology and plant uptake of PAHs. An understanding of plant root morp... | ['Biodegradation, Environmental', 'Linear Models', 'Phenanthrenes', 'Plant Roots', 'Soil Pollutants'] | 23,708,267 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['D02.455.426.559.847.723', 'D04.615.723'], ['A18.400'], ['D27.888.284.756']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Can the Myocardial Performance Index Be Used as a New Predictive Factor for a Poor Prognosis in Fetuses With Idiopathic Polyhydramnios? | OBJECTIVES: The purpose of this study was to determine whether there are any changes in cardiac function in fetuses with idiopathic polyhydramnios and also to evaluate the value of the myocardial performance index for prediction of adverse perinatal outcomes.METHODS: A prospective case-control study was conducted with ... | ['Adult', 'Case-Control Studies', 'Female', 'Fetal Heart', 'Humans', 'Polyhydramnios', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies'] | 27,821,651 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A07.541.278', 'A16.378.303'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.610'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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