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In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes. | RATIONALE: Repolarization alternans (RA) are associated with arrhythmogenesis. Animal studies have revealed potential mechanisms, but human-focused studies are needed. RA generation and frequency dependence may be determined by cell-to-cell variability in protein expression, which is regulated by genetic and external f... | ['Action Potentials', 'Aged', 'Arrhythmias, Cardiac', 'Calcium Channels, L-Type', 'Calcium Signaling', 'Computer Simulation', 'Electrophysiologic Techniques, Cardiac', 'Female', 'Heart Rate', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Models, Cardiovascular', 'Myocytes, Cardiac', 'Predictive Value of Tests',... | 26,602,864 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['L01.224.160'], ['E01.370.370.380.245', 'E01.370.405... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Flexible sigmoidoscopy in primary care. The procedure and its potential. | In comparison with the rigid sigmoidoscope, the flexible instrument has certain advantages that enhance its value in the office setting. This article describes one institution's success with the flexible scope in outpatient examinations and the proper technique for its use. | ['Colon', 'Family Practice', 'Fiber Optic Technology', 'Humans', 'Intestinal Polyps', 'Sigmoidoscopes', 'Sigmoidoscopy'] | 7,134,069 | [['A03.556.124.526.356', 'A03.556.249.249.356'], ['H02.403.340.500'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.825.411'], ['E07.230.220.260.160.800', 'E07.858.240.260.160.800'], ['E01.370.372.250.250.200.700', 'E01.370.388.250.250.250.160.800', 'E04.210.240.250.160.800', 'E04.502.... | ['Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A heterogeneous sialic acid-binding lectin with affinity for bacterial LPS from horse mussel (Modiolus modiolus) hemolymph. | A sialic acid-binding lectin that agglutinates a variety of erythrocytes and bacteria and react with sialoconjugates and purified lipopolysaccharides from marine vibrios has been affinity purified from hemolymph of the horse mussel Modiolus modiolus using Bovine submaxillary mucin conjugated to CNBr-activated Sepharose... | ['Animals', 'Binding Sites', 'Bivalvia', 'Calcium', 'Carbohydrate Metabolism', 'Carbohydrate Sequence', 'Cations, Divalent', 'Chromatography, Gel', 'Electrophoresis, Polyacrylamide Gel', 'Hemagglutination', 'Hemolymph', 'Horses', 'Humans', 'Lectins', 'Lipopolysaccharides', 'Macromolecular Substances', 'N-Acetylneuramin... | 9,226,886 | [['B01.050'], ['G02.111.570.120'], ['B01.050.500.644.080'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.158', 'G03.191'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D01.248.497.300.333'], ['E05.196.181.400.250'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.026.500', 'G12.122.100.200'], ['A... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Promoter activity of the 1731 Drosophila retrotransposon in a human monocytic cell line. | The resemblance between retrotransposons and retroviruses suggests an evolutionary relationship and indicates that they may share common transcription factors. We have analyzed the behaviour of the Drosophila 1731 retrotransposon promoter in the human monocytic U937 cell line. We show that the long terminal repeat (LTR... | ['Animals', 'Base Sequence', 'Binding Sites', 'Cell Line', 'Chloramphenicol O-Acetyltransferase', 'Cloning, Molecular', 'DNA', 'DNA Transposable Elements', 'Deoxyribonuclease I', 'Drosophila melanogaster', 'Humans', 'Molecular Sequence Data', 'Monocytes', 'Nuclear Proteins', 'Promoter Regions, Genetic', 'Repetitive Seq... | 8,391,472 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251.210'], ['D08.811.913.050.134.170'], ['E05.393.220'], ['D13.444.308'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D08.811.277.352.335.350.250'], ['B01.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of acute cimetidine administration on indices of parathyroid hormone action in healthy subjects and patients with primary and secondary hyperparathyroidism. | To evaluate the acute effect of histamine H2-receptor blockade with cimetidine on PTH concentrations and its endogenous biological activity, we studied the effect of iv administration of cimetidine (50-mg bolus followed by 500 mg/60 min infusion) in normal subjects and patients with primary and secondary hyperparathyro... | ['Adult', 'Aged', 'Calcium', 'Cimetidine', 'Cyclic AMP', 'Female', 'Humans', 'Hyperparathyroidism', 'Hyperparathyroidism, Secondary', 'Male', 'Middle Aged', 'Parathyroid Hormone', 'Phosphorus'] | 6,090,499 | [['M01.060.116'], ['M01.060.116.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.078.370.200', 'D03.383.129.308.130'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355'], ['C19.642.355.480'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alteration of cell growth and morphology by overexpression of transforming growth factor beta type II receptor in human lung adenocarcinoma cells. | TGF-beta is a potent inhibitory regulator of cell growth, which is transduced through interaction between type I (RI) and type II (RII) receptors that form heteromeric kinase complexes. Abnormal expression of these receptors has been identified in several human epithelial cancers and has been shown to be highly associa... | ['Adenocarcinoma', 'Cell Division', 'Cell Transformation, Neoplastic', 'Cyclin A', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'RNA, Messenger', 'Receptors, Transforming Growth Factor beta', 'Retinoblastoma Protein', 'Transfection', 'Transforming Growth Factor beta', 'Tumor Cells, Cultured'] | 11,165,397 | [['C04.557.470.200.025'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D12.644.360.262.100', 'D12.776.167.218.100', 'D12.776.476.262.100'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', ... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A pilot study of immunosuppression minimization after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy. | AIMS: To determine outcomes utilizing thymoglobulin and sirolimus immunosuppression, with early steroid withdrawal in low-immune responder pancreas-kidney (SPK) recipients, and conversion from cyclosporine (CsA) to mycophenolic acid (MPA) in all recipients at 6 months posttransplantation.METHODS: SPK recipients receive... | ['Animals', 'Antibodies', 'Antilymphocyte Serum', 'Graft Survival', 'Humans', 'Immunosuppressive Agents', 'Kidney Transplantation', 'Pancreas Transplantation', 'Pilot Projects', 'Prospective Studies', 'Rabbits', 'Sirolimus', 'T-Lymphocytes', 'Treatment Outcome'] | 16,298,653 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intravenous immunoglobulin treatment in women with recurrent abortions: increased cytokine levels and reduced Th1/Th2 lymphocyte ratio in peripheral blood. | PROBLEM: The aim of this study was to investigate changes in peripheral blood Th1/Th2 cytokine levels and lymphocyte ratios after massive intravenous immunoglobulin (MIVIg) treatment for women with recurrent spontaneous abortion (RSA) of unexplained etiology.METHOD OF STUDY: Serum Th1 (IFN-gamma, TNF-alpha) and Th2 cyt... | ['Abortion, Habitual', 'Animals', 'Cytokines', 'Female', 'Humans', 'Immunoglobulins, Intravenous', 'Immunotherapy', 'Mice', 'Th1 Cells', 'Th2 Cells'] | 12,765,346 | [['C13.703.039.089'], ['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393.536', 'D12.776.124.486.485.114.632', 'D12.776.124.790.651.114.632', 'D12.776.377.715.548.114.632'], ['E02.095.465.425'], ['B01.050.150.900.649.313.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Who's minding our profession? Assessing the quality of nursing performance, part 1. | Part 1 of this two-part series examines a newly endorsed set of evidence-based measures aimed specifically at assessing nursing performance. | ['Evidence-Based Medicine', 'Humans', 'Information Systems', 'Nursing Care', 'Nursing Service, Hospital', 'Quality Indicators, Health Care', 'United States'] | 15,069,348 | [['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.300'], ['E02.760.611', 'N02.421.533'], ['N02.278.216.500.968.489', 'N02.421.539.180', 'N04.452.442.452.422.489'], ['N04.761.789', 'N05.715.760'], ['Z01.107.567.875']] | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Clinical presentation of infection in granulocytopenic patients. | Inability to accurately diagnose infection in granulocytopenic patients is a major cause for morbidity and mortality, and prompted this study of 344 infections (pharyngitis, skin infection, pneumonia, anorectal infection, and urinary tract infection) in a select group of cancer patients. Strikingly similar alterations ... | ['Adolescent', 'Adult', 'Aged', 'Agranulocytosis', 'Child', 'Female', 'Humans', 'Infections', 'Male', 'Middle Aged', 'Pharyngitis', 'Pneumonia', 'Rectal Diseases', 'Skin Diseases, Infectious', 'Urinary Tract Infections'] | 1,052,668 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C15.378.553.546.184'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['M01.060.116.630'], ['C01.748.561', 'C07.550.781', 'C08.730.561', 'C09.775.649'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['C06.405.469.860'], ['C01.800', '... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
High-throughput and sensitive screening by ultra-performance liquid chromatography tandem mass spectrometry of diuretics and other doping agents. | The reliability of ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC- MS/MS) for high throughput screening in anti-doping control has been tested. A method to screen for the presence of diuretics and other doping agents in urine has been optimised and validated. The extraction procedure ... | ['Central Nervous System Stimulants', 'Chromatography, High Pressure Liquid', 'Diuretics', 'Doping in Sports', 'Humans', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrometry, Mass, Electrospray Ionization', 'Substance Abuse Detection', 'Tandem Mass Spectrometry'] | 18,708,699 | [['D27.505.696.282', 'D27.505.954.427.220'], ['E05.196.181.400.300'], ['D27.505.696.560.500'], ['I01.880.735.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Student-Led Training Day Increases Student Confidence in Women's Primary Care Skills. | BACKGROUND AND OBJECTIVES: Medical students are often apprehensive in approaching basic women's health concepts, including wellness exams, reproductive health concerns, and patient counseling. This study evaluates a novel student-developed and student-run Women's Health Training Day (WHTD) as a means of cultivating med... | ['Clinical Competence', 'Curriculum', 'Education, Medical, Undergraduate', 'Female', 'Humans', 'Male', 'Primary Health Care', 'Students, Medical', "Women's Health", 'Young Adult'] | 27,472,793 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.399.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.727'], ['M01.848.769.602'], ['N01.400.900'], ['M01.060.116.815']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Parietal endometriosis in abdominal scars. Report of 3 cases]. | Parietal endometriosis is a rare disease. Its diagnosis and treatment are often difficult. We report 3 cases of parietal endometriosis occurring in cesarean and appendectomy scars. Clinical symptoms are not specific and may lead to erroneous diagnosis. Diagnosis is usually made on the histological exam of the resected ... | ['Abdomen', 'Adult', 'Appendectomy', 'Cesarean Section', 'Cicatrix', 'Diagnosis, Differential', 'Endometriosis', 'Female', 'Humans', 'Postoperative Complications'] | 10,456,310 | [['A01.923.047'], ['M01.060.116'], ['E04.210.078'], ['E04.520.252.500'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E01.171'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767']] | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complex fracture-dislocation of the proximal interphalangeal joint of the hand. Results of a modified pins and rubbers traction system. | We reviewed 13 patients with a complex fracture-dislocation of the proximal interphalangeal joint of a finger and one patient with a complex fracture-dislocation of the interphalangeal joint of thumb. We had treated these injuries using a pins and rubbers traction system which had been modified to avoid friction of the... | ['Adolescent', 'Adult', 'Female', 'Finger Injuries', 'Finger Joint', 'Fractures, Bone', 'Humans', 'Joint Dislocations', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Thumb', 'Time Factors', 'Traction', 'Treatment Outcome'] | 15,125,130 | [['M01.060.057'], ['M01.060.116'], ['C26.448.429'], ['A02.835.583.405.350'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['M01.060.116.630'], ['C23.550.767'], ['E01.370.350.700'], ['A01.378.800.667.430.705'], ['G01.910.857'], ['E04.555.720'], ['E01.789.800', 'N04.761.559.59... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oleic acid increases cell surface expression and activity of CD11b on human neutrophils. | Traumatic bone injury frequently results in the release of marrow-derived fatty material into the circulation. This may lead to the syndrome of fat embolism, associated with the generation of free fatty acids, the sequestration of neutrophils in the lungs, and the subsequent development of acute respiratory distress. N... | ['Cells, Cultured', 'Humans', 'Macrophage-1 Antigen', 'Neutrophil Activation', 'Neutrophils', 'Oleic Acid'] | 9,780,202 | [['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408.495.500', 'D12.776.543.750.705.408.600.500', 'D12.776.543.750.705.833.500'], ['G12.604'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D10.251.355... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of multiple sclerosis patients at highest risk of cognitive impairment using an integrated brain magnetic resonance imaging assessment approach. | BACKGROUND AND PURPOSE: While impaired cognitive performance is common in multiple sclerosis (MS), it has been largely underdiagnosed. Here a magnetic resonance imaging (MRI) screening algorithm is proposed to identify patients at highest risk of cognitive impairment. The objective was to examine whether assessment of ... | ['Adult', 'Atrophy', 'Brain', 'Cognitive Dysfunction', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Neuropsychological Tests'] | 27,873,386 | [['M01.060.116'], ['C23.300.070'], ['A08.186.211'], ['F03.615.250.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F04.711.513']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Origin of orientation-dependent asymmetries in vestibulo-ocular reflexes evoked by caloric stimulation. | A caloric stimulus evokes primarily a horizontal vestibulo-ocular reflex (VOR) when subjects are in a supine or prone orientation with the horizontal semicircular canal plane oriented vertically. In both monkeys and humans, the magnitude of VOR eye movements is greater in the supine than in the prone orientation, indic... | ['Adult', 'Ear, External', 'Eye Movements', 'Female', 'Functional Laterality', 'Hot Temperature', 'Humans', 'Male', 'Middle Aged', 'Models, Neurological', 'Motion Sickness', 'Orientation', 'Otolithic Membrane', 'Physical Stimulation', 'Posture', 'Prone Position', 'Reflex, Vestibulo-Ocular', 'Supine Position'] | 15,175,373 | [['M01.060.116'], ['A09.246.272'], ['G11.427.410.140', 'G14.350'], ['F02.830.297.425', 'G11.561.225.425'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Psychiatric sequelae following surgical treatment of breast cancer. | Breast cancer has been the most carefully studied site of tumor from a psychological point of view. A range of interventions have been developed to assist the woman and her family in the emotional adjustment to breast cancer and its treatment. Many of these have been developed 'by women for women' and by their insisten... | ['Adaptation, Psychological', 'Adjustment Disorders', 'Breast', 'Breast Neoplasms', 'Combined Modality Therapy', 'Female', 'Humans', 'Mastectomy', 'Neurocognitive Disorders', 'Patient Participation', 'Postoperative Complications', 'Prognosis', 'Prostheses and Implants'] | 3,706,032 | [['F01.058'], ['F03.950.500'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466'], ['F03.615'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.360.300', 'N05.300.150.800.500.620'], ['C23.550.767'], ['E01.... | ['Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Role of NMDA and AMPA glutamate receptors in the mechanism of korazol-induced convulsions in mice]. | The potency of mono- and dikationic derivatives of adamantane and phenylcyclohexyl to prevent seizures induced in mice by intraperitoneal administration of 80 mg/kg pentylenetetrazol (corazol), was studied. Monocationic derivatives of phenylcyclohexyl, being the selective channel blockers of NMDA glutamate receptors, a... | ['Animals', 'Anticonvulsants', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Male', 'Mice', 'Molecular Structure', 'Pentylenetetrazole', 'Receptors, AMPA', 'Receptors, N-Methyl-D-Aspartate', 'Seizures'] | 12,968,522 | [['B01.050'], ['D27.505.954.427.080'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.111.570', 'G02.466'], ['D03.383.066.600'], ['D12.776.157.530.400.400.500.100', 'D12.776.543.550.450.500.200.100', 'D12.776.543.585.400.500.200.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypercapnia-induced increases in cerebral blood flow do not improve lower body negative pressure tolerance during hyperthermia. | Heat-related decreases in cerebral perfusion are partly the result of ventilatory-related reductions in arterial CO2 tension. Cerebral perfusion likely contributes to an individual's tolerance to a challenge like lower body negative pressure (LBNP). Thus increasing cerebral perfusion may prolong LBNP tolerance. This st... | ['Adaptation, Physiological', 'Adult', 'Blood Flow Velocity', 'Blood Pressure', 'Cerebrovascular Circulation', 'Female', 'Fever', 'Humans', 'Hypercapnia', 'Lower Body Negative Pressure', 'Male'] | 23,864,641 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.100.159'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['E02.278.500']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computerized dynamic platform posturography. | Computerized dynamic platform posturography is defined in this technology assessment. The review discusses what computerized dynamic platform posturography measures, what the reliability and validity of the information are, and the uniqueness of the information provided. The clinical contribution and indications for te... | ['Diagnostic Techniques, Neurological', 'Diagnostic Techniques, Otological', 'Humans', 'Postural Balance', 'Posture', 'Psychomotor Performance', 'Reproducibility of Results', 'Sensation Disorders', 'Signal Processing, Computer-Assisted', 'Technology Assessment, Biomedical', 'Vestibular Function Tests'] | 9,339,802 | [['E01.370.376'], ['E01.370.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G11.427.695'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['C10.597.75... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Transcriptional profiling of wine yeast in fermenting grape juice: regulatory effect of diammonium phosphate. | The nitrogen composition of grape musts affects fermentation kinetics and production of aroma and spoilage compounds in wine. It is common practice in wineries to supplement grape musts with diammonium phosphate (DAP) to prevent nitrogen-related fermentation problems. Laboratory strains of Saccharomyces cerevisiae pref... | ['Alcohols', 'Amino Acids, Branched-Chain', 'Arginine', 'Beverages', 'Fermentation', 'Gene Expression Profiling', 'Gene Expression Regulation, Fungal', 'Models, Biological', 'Nitrogen', 'Phosphates', 'Saccharomyces cerevisiae', 'Up-Regulation', 'Urea', 'Wine'] | 12,689,635 | [['D02.033'], ['D12.125.070'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G07.203.100', 'J02.200'], ['G02.111.158.249', 'G03.191.249'], ['E05.393.332'], ['G05.308.330'], ['E05.599.395'], ['D01.268.604', 'D01.362.625'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['B01.30... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Considerations on a group of 13 patients with Creutzfeldt-Jakob disease in the region of Parma (Italy) | We report a group of 13 cases of Creutzfeldt-Jakob disease treated in the region of Parma (Italy) between 1975 and 1984. An extensive study did not point to any common source of infection. The clinical stereotypy and distinctive neuropathology in this temporo-spatially confined group of patients might be stressed, but ... | ['Aged', 'Animals', 'Astrocytes', 'Brain', 'Creutzfeldt-Jakob Syndrome', 'Environmental Exposure', 'Female', 'Humans', 'Hyperplasia', 'Hypertrophy', 'Italy', 'Male', 'Middle Aged', 'Space-Time Clustering'] | 2,253,725 | [['M01.060.116.100'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['C01.207.800.230', 'C10.228.140.380.165', 'C10.228.228.800.230', 'F03.615.400.300'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['C23.300.775'], ['Z01.542.489'], ['M01.060.116.630'], ['E05.31... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Stages of change, treatment outcome and therapeutic alliance in adult inpatients with chronic anorexia nervosa. | BACKGROUND: Anorexia nervosa (AN) is associated with high rates of chronicity and relapse risk is a considerable therapeutic challenge in the disorder. The aim of the present study was to investigate the association of stages of change and outcome with a focus on the relapse struggle in the maintenance stage in patient... | ['Adolescent', 'Adult', 'Anorexia Nervosa', 'Female', 'Humans', 'Inpatients', 'Male', 'Motivation', 'Professional-Patient Relations', 'Psychiatric Status Rating Scales', 'Psychotherapy', 'Recurrence', 'Treatment Outcome'] | 23,570,454 | [['M01.060.057'], ['M01.060.116'], ['F03.400.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['F01.658', 'F01.752.543.500.750'], ['F01.829.401.650', 'N05.300.660'], ['F04.711.513.653'], ['F04.754'], ['C23.550.291.937'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reciprocal effects of hyper- and hypoactivity mutations in the Drosophila pattern gene torso. | In Drosophila, five "terminal" polarity genes must be active in females in order for them to produce embryos with normal anterior and posterior ends. Hypoactivity mutations in one such gene, torso, result in the loss of the most posterior domain of fushi tarazu expression and the terminal cuticular structures. In contr... | ['Abdomen', 'Alleles', 'Animals', 'Cytoplasm', 'Drosophila', 'Female', 'Gene Expression Regulation', 'Mutation', 'Phenotype', 'Suppression, Genetic', 'Thorax'] | 2,922,596 | [['A01.923.047'], ['G05.360.340.024.340.030'], ['B01.050'], ['A11.284.430.214'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G05.308'], ['G05.365.590'], ['G05.695'], ['G05.365.590.835', 'G05.558.835'], ['A01.923.761']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Both the fast and slow refolding reactions of ribonuclease A yield native enzyme. | The fast reaction ((T2) approximately 50 msec) observed previously in the refolding of thermally unfolded ribonuclease A (disulfide bonds intact) has now been studied by two properties indicative of enzyme function: binding of a competitive inhibitor (2'CMP) and hydrolysis of a substrate (CpA --> C > p + A). Both the b... | ['Binding Sites', 'Cytosine Nucleotides', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Kinetics', 'Protein Conformation', 'Ribonucleases', 'Spectrophotometry', 'Structure-Activity Relationship', 'Tyrosine'] | 4,519,627 | [['G02.111.570.120'], ['D03.383.742.686.246', 'D13.695.740.246', 'D13.695.827.232'], ['G02.300'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['G02.111.570.820.709'], ['D08.811.277.352.700'], ['E05.196.712.726', 'E05.196.867.826'], ['G02.111.830', 'G07.690.773.997'], ['D12.125.072.050.875']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protocol for treatment of Achilles tendon ruptures; a systematic review with network meta-analysis. | BACKGROUND: Achilles tendon ruptures are a common injury and are increasing in incidence. Several management strategies exist for both non-operative and operative care, with each strategy offering unique risks and benefits. Traditional pairwise meta-analyses have been performed to compare management strategies; however... | ['Achilles Tendon', 'Humans', 'Network Meta-Analysis', 'Orthopedics', 'Physical Therapy Modalities', 'Postoperative Complications', 'Randomized Controlled Trials as Topic', 'Rupture', 'Surgical Procedures, Operative'] | 30,580,763 | [['A02.880.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500.500', 'E05.581.500.501.500', 'N05.715.360.325.515.500', 'N06.850.520.445.500.500'], ['H02.403.810.494'], ['E02.779', 'E02.831.535'], ['C23.550.767'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.2... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Hepatitis B virus markers among family contacts and medical personnel of 239 hemodialysis patients. | The present study was initiated to assess the risk of infection of medical personnel and family contacts of hemodialysis patients. It confirms previous reports that hemodialysis patients and staff members of hemodialysis units are at high risk of acquiring HBV infection. Approximately 25% of the household contacts had ... | ['Antibodies, Viral', 'Carrier State', 'Cross Infection', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Surface Antigens', 'Hospital Units', 'Humans', 'Personnel, Hospital', 'Renal Dialysis'] | 7,408,256 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['N06.850.520.169'], ['C01.248', 'C23.550.291.875.500'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of balloon inflation volume on pulmonary artery occlusion pressure in patients with and without pulmonary hypertension. | BACKGROUND: Pulmonary artery occlusion pressure (PAOP) is used to differentiate patients with pulmonary hypertension (PH) associated with left-sided heart disease from other etiologies. Technical errors in the measurement of PAOP are common and lead to incorrect classification of the etiology of PH. We investigated the... | ['Catheterization', 'Catheterization, Central Venous', 'Female', 'Follow-Up Studies', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Pulmonary Artery', 'Pulmonary Wedge Pressure', 'Retrospective Studies'] | 20,595,458 | [['E02.148', 'E05.157'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.116.630'], ['A07.015.114.715'], ['G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effects of five different polar extracts from Herba pogostemonis being gotten rid of volatile oil on gastrointestinal tract]. | The effects of the five extracts from Herba pogostmonis being gotten rid of volatile oil on gastrointestinal tract were studied. The results showed that the five extracts could increase gastric secretion of acid and activity of pepsin, reduce the incidence of diarrhea induced by Folium sennae and relieve the gripping p... | ['Animals', 'Drugs, Chinese Herbal', 'Female', 'Gastrointestinal Agents', 'Gastrointestinal Transit', 'Lamiaceae', 'Male', 'Mice', 'Rats'] | 11,563,190 | [['B01.050'], ['D20.215.784.500.350', 'D26.335'], ['D27.505.954.483'], ['E01.370.372.310', 'G10.261.360.525'], ['B01.650.940.800.575.912.250.583.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and structural characterization of strontium- and magnesium-co-substituted beta-tricalcium phosphate. | The synthesis of five different Sr(2+)- and Mg(2+)-co-substituted beta-tricalcium phosphate (beta-TCP) has been obtained by heating the calcium-deficient apatites above 800 degrees C. With the investigated concentrations of Sr(2+) and Mg(2+) from the present study, no additional phases other than beta-TCP have been det... | ['Calcium Phosphates', 'Magnesium', 'Spectroscopy, Fourier Transform Infrared', 'Strontium', 'X-Ray Diffraction'] | 19,679,202 | [['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['D01.268.552.850', 'D01.268.556.825', 'D01.552.539.861', 'D01.552.544.825'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extracorporeal life support in the acute management of tumour lysis syndrome. | A 16-month old boy presented with a severe tumour lysis syndrome (TLS) complicating induction therapy for acute myeloid leukaemia. This was further complicated by a respiratory syncytial virus infection. The failure of response to escalating treatment necessitated the use of extracorporeal life support (ECLS) during co... | ['Antineoplastic Agents', 'Extracorporeal Membrane Oxygenation', 'Humans', 'Infant', 'Leukemia, Myeloid, Acute', 'Male', 'Tumor Lysis Syndrome'] | 22,647,970 | [['D27.505.954.248'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.337.539.275'], ['C15.604.515.880', 'C20.683.515.950']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Factors affecting discharge destination following lung transplantation. | BACKGROUND: Lung transplant (LT) recipients requiring additional care may be referred to inpatient rehabilitation prior to discharge home. This study seeks to describe discharge destinations following LT, compare the characteristics of patients discharged to different destinations, and identify the predictors of discha... | ['Adult', 'Female', 'Follow-Up Studies', 'Home Care Services', 'Humans', 'Inpatients', 'Intensive Care Units', 'Length of Stay', 'Lung Diseases', 'Lung Transplantation', 'Male', 'Middle Aged', 'Patient Discharge', 'Prognosis', 'Recovery of Function', 'Rehabilitation Centers', 'Respiration, Artificial', 'Retrospective S... | 25,918,985 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['N02.278.388.493'], ['E02.760.400.480', 'N02.421.585.400.480'], ['C08.381'], ['E04.928.600.495', 'E04.93... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Primary reconstruction after extensive chest wall resection. | BACKGROUND: Chest wall resection and reconstruction has been proven to be a safe surgical procedure. This is particularly useful for breast cancer patients with chest wall recurrences or for those who first present with locally advanced cancer in the chest wall where there is both a large soft tissue and bony defect th... | ['Bone Neoplasms', 'Breast Neoplasms', 'Female', 'Humans', 'Lung Neoplasms', 'Mastectomy', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Reconstructive Surgical Procedures', 'Surgical Flaps', 'Survival Analysis', 'Thoracic Surgical Procedures'] | 9,737,263 | [['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E04.466'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E04.680'], ['A10.850.710', 'E07.862.710'], ['E05.318.740.998', 'N05.715.360... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Copper, lead, cadmium and calcium in cataractous lenses. | Lenticular copper, lead, cadmium and calcium levels were measured using atomic absorption spectrophotometry in 9 normal and 37 cataractous human lenses. The nuclear parts of the lenses were used for the study in both groups. The lenticular deposition of these four elements in cataract was statistically significantly. I... | ['Cadmium', 'Calcium', 'Cataract', 'Copper', 'Female', 'Humans', 'Lead', 'Lens Nucleus, Crystalline', 'Male', 'Middle Aged', 'Sex Characteristics', 'Spectrophotometry, Atomic'] | 9,483,588 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C11.510.245'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.435', 'D01.552.544.435'], ['A09.371.060.500.670'], ['M01.060.116.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The differences in chromogranin A (CgA) concentrations measured in serum and in plasma by IRMA and ELISA methods. | INTRODUCTION: Chromogranin A (CgA) is regarded as a major, nonspecific marker of neuroendocrine tumors (NET). Its estimation appears helpful for diagnostic purposes and is particularly useful for monitoring the treatment of NET. It must be kept in mind, however, that various factors, drugs, or coexisting diseases may i... | ['Biomarkers, Tumor', 'Chromogranin A', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoradiometric Assay', 'Plasma', 'Reference Values', 'Serum'] | 20,806,177 | [['D23.101.140'], ['D12.776.631.199.249'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.639.405', 'E05.601.470.639.405'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['E05.97... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An examination of Escherichia coli strains isolated from cases of bovine mastitis for possible virulence determinants. | Ninety-five strains of Escherichia coli isolated from cases of bovine mastitis were examined for the possession of some of the possible virulence determinants. Ten strains which caused haemagglutination of bovine and ovine erythrocytes were considered to be fimbriated and an additional strain caused agglutination of ch... | ['Animals', 'Antigens', 'Antigens, Bacterial', 'Antigens, Surface', 'Cattle', 'Colicins', 'Escherichia coli', 'Female', 'Fimbriae, Bacterial', 'Hemagglutination', 'Hemagglutinins', 'Mastitis, Bovine', 'Virulence'] | 6,135,266 | [['B01.050'], ['D23.050'], ['D23.050.161'], ['D23.050.301'], ['B01.050.150.900.649.313.500.380.271'], ['D12.776.097.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.284.180.285', 'A20.843'], ['G02.111.026.500', 'G12.122.100.200'], ['D27.505.696.477.136.377'], ['C22.196.581'], ['G06.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone marrow sampling in pathologic fractures: intramedullary pediatric chest tube technique. | The objective of this article is to report upon a simple technique of bone marrow specimen collection of intramedullary bone tumors using a pediatric chest tube. This technique is described along with two case reports which include a 60-year-old female with metastatic breast cancer to the proximal femur, and a 63-year-... | ['Biopsy, Needle', 'Bone Marrow', 'Bone Marrow Neoplasms', 'Breast Neoplasms', 'Carcinoma', 'Chest Tubes', 'Female', 'Femoral Fractures', 'Humans', 'Humeral Fractures', 'Male', 'Middle Aged', 'Multiple Myeloma'] | 15,105,753 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['A15.382.216'], ['C04.588.448.200', 'C15.378.190.250', 'C15.378.400.200'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antitumor and antiangiogenic activity of Schisandra chinensis polysaccharide in a renal cell carcinoma model. | The aim of this study was to determine the antitumor and antiangiogenic effects of the Schisandra chinensis polysaccharides (SCP) in selected renal cell carcinoma (RCC) cells and evaluate its potential mechanism of action. In vitro, endothelial growth factor (VEGF) secretion by Caki-1 was blockaded in response to SCP t... | ['Angiogenesis Inhibitors', 'Animals', 'Antigens, CD34', 'Antineoplastic Agents', 'Apoptosis', 'Carcinoma, Renal Cell', 'Cell Line, Tumor', 'Humans', 'Kidney Neoplasms', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Neovascularization, Pathologic', 'Platelet Endothelial Cell Adhesion Molecule-1', 'Polysaccharid... | 24,556,120 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D27.505.954.248'], ['G04.146.954.035'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of septal hyperreactivity by testosterone and its reversion by an estrogen antagonist in weanling female rats. | Neonatal administration of testosterone inhibits emotional hyperreactivity to capture and tactile stimulation in female rats following septal lesions at 25 days of age. Testosterone, an aromatizable androgen, after metabolization to estrogen interacts with estrogen receptors in neonatal rat brain. In order to investiga... | ['Animals', 'Animals, Newborn', 'Arousal', 'Emotions', 'Estradiol', 'Female', 'Rats', 'Rats, Inbred Strains', 'Septum Pellucidum', 'Sex Factors', 'Tamoxifen', 'Testosterone'] | 6,633,974 | [['B01.050'], ['B01.050.050.282'], ['F02.830.104', 'G11.561.035'], ['F01.470'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A08.186.211.140.814', 'A08.186.211.180.750.900', 'A08.186.211... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pollutant sources in an arsenic-affected multilayer aquifer in the Po Plain of Italy: Implications for drinking-water supply. | In aquifers 160 to 260m deep that used for public water-supply in an area ~150km2 around the town of Cremona, in the Po Plain of Northern Italy, concentrations of arsenic (As) are increasing with time in some wells. The increase is due to drawdown of As-polluted groundwater (As ?144ìg/L) from overlying aquifers at dept... | ['Arsenic', 'Drinking Water', 'Environmental Monitoring', 'Groundwater', 'Italy', 'Water Pollutants, Chemical', 'Water Supply'] | 27,836,337 | [['D01.268.513.249'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.355'], ['Z01.542.489'], ['D27.888.284.903.655'], ['J01.293.821.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Nonlinear pharmacokinetics of propafenone in rats and humans: application of a substrate depletion assay using hepatocytes for assessment of nonlinearity. | Linear pharmacokinetic profiles of propafenone in female Wistar rats were found after oral administration of up to 20 mg/kg. These profiles differed from nonlinear pharmacokinetics in a dose-dependent manner with increasing plasma concentrations in humans (Hollmann M, Brode E, Hotz D, Kaumeier S, and Kehrhahn OH (1983)... | ['Animals', 'Dose-Response Relationship, Drug', 'Female', 'Hepatocytes', 'Humans', 'Nonlinear Dynamics', 'Propafenone', 'Rats', 'Rats, Wistar', 'Species Specificity', 'Substrate Specificity'] | 15,743,979 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.850', 'H01.548.675'], ['D02.522.818.830'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G16.824'], ['G02.111.835']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Orthodontic microsurgery for rapid dental repositioning in dental malpositions. | PURPOSE: Malposition of dental elements can be easily corrected when the patient is young; however, the opposite is true for adults. Middle-age patients normally request a rapid solution, but they usually also have associated pathologic features, such as advanced periodontal disease, dental migration, and ankylosis. Sh... | ['Adolescent', 'Alveolar Process', 'Female', 'Humans', 'Male', 'Malocclusion', 'Microsurgery', 'Osteotomy', 'Palatal Expansion Technique', 'Time Factors', 'Tooth Ankylosis', 'Tooth Movement Techniques', 'Ultrasonics', 'Young Adult'] | 20,934,794 | [['M01.060.057'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494'], ['E04.494', 'E05.591.580'], ['E04.555.580'], ['E06.658.578.458'], ['G01.910.857'], ['C07.793.710'], ['E06.658.578.836'], ['H01.671.031.849'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Script knowledge after severe traumatic brain injury. | Severe diffuse traumatic brain injury (TBI) may impair the performance of daily-life complex activities. The aim of the present study was to assess whether these difficulties are related to a representational impairment of action knowledge. Two tasks requiring the manipulation of scripts were used. The first (script re... | ['Activities of Daily Living', 'Adult', 'Attention', 'Brain Injury, Chronic', 'Concept Formation', 'Diffuse Axonal Injury', 'Female', 'Glasgow Coma Scale', 'Head Injuries, Closed', 'Humans', 'Male', 'Mental Recall', 'Neuropsychological Tests', 'Problem Solving', 'Prognosis'] | 11,771,622 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['F02.830.104.214'], ['C10.228.140.140.127', 'C10.228.140.199.500', 'C10.900.300.087.250', 'C26.915.300.200.200'], ['F02.463.785.233'], ['C10.228.140.199.388.500', 'C10.900.300.087.219.500', 'C26.915.300.200.188.500'], ['E05.318... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Lidocaine-induced CNS toxicity--a case report. | Lidocaine is the first local anesthetic of the amide type to be introduced to clinical practice. It is a versatile drug and in anesthesia, is the most commonly used local anesthetic because of its aptness of potency, rapid onset, moderate duration of action and topical activity. It is relatively safe and useful in many... | ['Adult', 'Anesthetics, Local', 'Brain', 'Humans', 'Lidocaine', 'Male'] | 9,084,554 | [['M01.060.116'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.199.092.500', 'D02.092.146.113.092.500']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. | Farnesyl pyrophosphate (FPP), a key intermediate in the mevalonate pathway and protein farnesylation, can act as an agonist for several nuclear hormone receptors. Here we show a novel mechanism by which FPP inhibits wound healing acting as an agonist for glucocorticoid receptor (GR). Elevation of endogenous FPP by the ... | ['Animals', 'Bridged Bicyclo Compounds, Heterocyclic', 'Cattle', 'Cell Line', 'Cell Movement', 'Enzyme Inhibitors', 'Epithelial Cells', 'Farnesyl-Diphosphate Farnesyltransferase', 'Gene Expression Regulation', 'Glucocorticoids', 'Humans', 'Keratin-6', 'Keratinocytes', 'Ligands', 'Lovastatin', 'Polyisoprenyl Phosphates'... | 19,903,814 | [['B01.050'], ['D03.605.084'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['D27.505.519.389'], ['A11.436'], ['D08.811.913.225.431'], ['G05.308'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450.600.600'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Progesterone does not affect the amount of mRNA for gonadotropins in the anterior pituitary gland of ovariectomized ewes. | To evaluate the effect of progesterone on the synthesis and secretion of gonadotropins, ovariectomized ewes either were treated with progesterone (n = 5) for 3 wk or served as controls (n = 5) during the anestrous season. After treatment for 3 wk, blood samples were collected from progesterone-treated and ovariectomize... | ['Animals', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropins, Pituitary', 'Luteinizing Hormone', 'Nucleic Acid Hybridization', 'Ovariectomy', 'Progesterone', 'RNA, Messenger', 'Radioimmunoassay', 'Sheep'] | 3,126,840 | [['B01.050'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D12.644.548.691.525.343'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['E05.393.661', 'G02.111.611'], ['E04.270.282... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Continuous compression behaviors of selective laser melting Ti-6Al-4V alloy with cuboctahedron cellular structures. | Cellular structures often show fluctuating stresses in compression stress-strain curves. Such fluctuating stresses correspond to strut fractures. In this study, the cellular Ti-6Al-4V alloy with cuboctahedron structure was prepared by selective laser melting. The cuboctahedron cellular structures showed reduced fluctua... | ['Compressive Strength', 'Elastic Modulus', 'Lasers', 'Porosity', 'Stress, Mechanical', 'Titanium'] | 30,948,115 | [['G01.374.180'], ['G01.374.590.605'], ['E07.632.490', 'E07.710.520'], ['G01.374.710'], ['G01.374.835'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus. | This study was performed to test the hypothesis that cytotoxic T lymphocyte (CTL) selection of hepatitis C virus (HCV) escape variants plays a role in HCV persistence. The peripheral blood CTL responsiveness of patients with well-established chronic hepatitis C to a panel of 10 prototype HCV peptides (genotype 1a) was ... | ['Adult', 'Amino Acid Sequence', 'Chronic Disease', 'Cross Reactions', 'Cytotoxicity, Immunologic', 'Female', 'HLA-A2 Antigen', 'Hepacivirus', 'Hepatitis Antigens', 'Hepatitis C', 'Humans', 'Male', 'Middle Aged', 'Peptide Fragments', 'Protein Binding', 'Structure-Activity Relationship', 'T-Lymphocytes, Cytotoxic'] | 9,410,918 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C23.550.291.500'], ['G12.122.281'], ['G12.287'], ['D12.776.395.550.489.400.020', 'D12.776.543.550.439.400.020', 'D23.050.301.500.100.400.020', 'D23.050.301.500.450.370.020', 'D23.050.705.552.100.400.020', 'D23.050.705.552.450.370.374'], ['B04.450.380', 'B0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B. | A recombinant Epstein-Barr virus (EBV) was constructed, with a positive-selection marker inserted at the site of a deletion of a DNA segment which encodes the first five transmembrane domains of LMP2A and LMP2B. Despite the mutation, the mutant recombinant EBV was able to initiate and maintain primary B-lymphocyte grow... | ['Amino Acid Sequence', 'Antigens, Viral', 'B-Lymphocytes', 'Base Sequence', 'Blotting, Southern', 'Cell Transformation, Viral', 'DNA, Viral', 'Gene Expression', 'Genes, Viral', 'Herpesvirus 4, Human', 'Humans', 'Lymphocyte Activation', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Polymerase Chain Reaction'... | 8,392,630 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.327'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['C04.697.098.500.160',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chemical synthesis of the M-factor mating pheromone from Schizosaccharomyces pombe. | Conjugation in the fission yeast Schizosaccharomyces pombe is controlled by the reciprocal action of mating pheromones. We recently showed that M-factor, the pheromone released by cells of the cellular mating type Minus, is a nonapeptide in which the C-terminal cysteine residue is carboxyl-methylated and S-alkylated, p... | ['Amino Acid Sequence', 'DNA-Binding Proteins', 'Intercellular Signaling Peptides and Proteins', 'Molecular Sequence Data', 'Peptides', 'Pheromones', 'Schizosaccharomyces', 'Schizosaccharomyces pombe Proteins'] | 7,941,744 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.260'], ['D12.644.276', 'D12.776.467', 'D23.529'], ['L01.453.245.667'], ['D12.644'], ['D23.641'], ['B01.300.107.797', 'B01.300.930.720'], ['D12.776.354.875']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ceruloplasmin as a marker of occupational copper exposure. | Estimation of serum copper to indicate copper status in the human system in the context of moderate chronic occupational copper exposure requires a sophisticated and expensive method. Hence, a search for a suitable marker has been made and few studies have found potential in serum ceruloplasmin. In this context, the pr... | ['Adult', 'Alanine Transaminase', 'Alkaline Phosphatase', 'Biomarkers', 'Ceruloplasmin', 'Copper', 'Data Collection', 'Humans', 'Industry', 'Occupational Exposure', 'Risk Assessment', 'Surveys and Questionnaires', 'Time Factors'] | 18,285,839 | [['M01.060.116'], ['D08.811.913.477.700.100'], ['D08.811.277.352.650.035'], ['D23.101'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.318.308', 'L01.399.250', 'N05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Developing a strategy to identify and treat older patients with postoperative delirium. | Postoperative delirium is one of the most common adverse outcomes in elderly patients undergoing surgery and is associated with increased morbidity, length of stay, and patient care costs. The purpose of this quality improvement project was to evaluate the effectiveness of a multicomponent strategy to identify and trea... | ['Aged', 'Aged, 80 and over', 'Delirium', 'Education, Continuing', 'Female', 'Guideline Adherence', 'Humans', 'Male', 'Massachusetts', 'Postoperative Complications', 'Risk Factors', 'Societies, Nursing'] | 24,472,589 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['I02.358.212'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.550.510'], ['C23.550.767'], ['E05.318.740.600.800.725', 'N05.715.35... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
THE EFFECTS OF FENOLDOPAM ON RENAL FUNCTION AND METABOLISM IN AN OVINE MODEL OF SEPTIC SHOCK. | INTRODUCTION: The importance of renal perfusion and metabolism in septic acute kidney injury (AKI) remains unclear. Prophylactic administration of the dopaminergic agent, fenoldopam, has been suggested to reduce the occurrence of AKI, but its effects in septic shock are poorly defined.METHODS: Sepsis was induced in 15 ... | ['Animals', 'Disease Models, Animal', 'Female', 'Fenoldopam', 'Humans', 'Kidney', 'Kidney Function Tests', 'Sheep', 'Shock, Septic'] | 26,506,071 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.633.100.079.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E01.370.390.400'], ['B01.050.150.900.649.313.500.380.791'], ['C01.757.800', 'C23.550.470.790.500.800', 'C23.550.835.900.712']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of selective blockade of M4 cholinoreceptors by tropicamide on blood supply in brain, splanchnic azygous organs, and hindlimbs in intact rats. | Experiments on anesthetized rats carried out with a high-frequency ultrasonic system and tropicamide, a highly selective blocker of M4 cholinoreceptors, showed that the vasodilator effects observed after selective blockade of M4 cholinoreceptors are not organ-specific. Intravenous tropicamide (0.1 ìg/kg body weight) tr... | ['Animals', 'Blood Flow Velocity', 'Blood Pressure', 'Brain', 'Carotid Arteries', 'Femoral Artery', 'Hindlimb', 'Male', 'Mesenteric Artery, Superior', 'Muscarinic Antagonists', 'Rats', 'Rats, Wistar', 'Receptor, Muscarinic M4', 'Splanchnic Circulation', 'Tropicamide', 'Vascular Resistance', 'Vasodilator Agents'] | 24,824,684 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.186.211'], ['A07.015.114.186'], ['A07.015.114.351'], ['A13.473'], ['A07.015.114.565.755'], ['D27.505.519.625.120.200.500', 'D27.505.696.577.120.200.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.15... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mesothelin Expression in Advanced Gastroesophageal Cancer Represents a Novel Target for Immunotherapy. | The identification of new therapeutic targets is of profound importance if we are to improve outcomes in gastroesophageal cancer. This study assessed the rate of mesothelin expression in tumors of western patients with upper gastrointestinal tract carcinomas. In addition, the AGS gastric cancer cell line was tested for... | ['Adult', 'Aged', 'Cell Line, Tumor', 'Esophageal Neoplasms', 'Female', 'GPI-Linked Proteins', 'Humans', 'Immunotherapy', 'Male', 'Middle Aged', 'Stomach Neoplasms', 'Young Adult'] | 26,894,650 | [['M01.060.116'], ['M01.060.116.100'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'],... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dual action of zinc on ileal smooth muscle--zinc-calcium interaction. | Effect of zinc sulphate was studied on histamine-induced contractions on guinea-pig ileum. In doses of 1.72 X 10(-7)M or less no effects were observed. Zinc sulphate in doses of 3.44 X 10(-7)M, 6.88 X 10(-7)M and 1.72 X 10(-6)M produced dual effect. Short exposure of tissue for 10 min to zinc sulphate resulted in signi... | ['Animals', 'Calcium', 'Drug Interactions', 'Female', 'Guinea Pigs', 'Histamine', 'Ileum', 'In Vitro Techniques', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Zinc'] | 3,570,433 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.690.773.968'], ['B01.050.150.900.649.313.992.550'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['A03.556.124.684.249', 'A03.556.249.124'], ['E05.481'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. | Human urotensin-II (hU-II) is the most potent endogenous cardiostimulant identified to date. We therefore determined whether hU-II has a possible pathological role by investigating its levels in patients with congestive heart failure (CHF). Blood samples were obtained from the aortic root, femoral artery, femoral vein,... | ['Case-Control Studies', 'Female', 'Furin', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Peptide Fragments', 'Radioimmunoassay', 'Subtilisins', 'Urotensins'] | 12,791,592 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D08.811.277.656.300.760.353', 'D08.811.277.656.837.249', 'D08.811.277.656.959.350.353'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.330.580', 'G11.427.494.570'], ['D12.644.541'], ['E01.370... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neonatal newborn hearing screening: four years' experience at Ferrara University Hospital (CHEAP project): part 1. | The Child Hearing Early Assessment Programme (CHEAP) regional project, was a combined departmental approach (Audiology, Neonatology) of the University Hospital of Ferrara, aimed at identifying neonatal hearing impairment and defining early intervention strategies. Aims of this project have been: (i) construction of a n... | ['Costs and Cost Analysis', 'Hearing Disorders', 'Hospitals, University', 'Humans', 'Infant', 'Infant, Newborn', 'Italy', 'Neonatal Screening'] | 17,601,205 | [['N03.219.151'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['Z01.542.489'], ['E01.370.225.910', 'E01.370.500.580', 'E05.200.910', 'E05.318.308.980.438.580.580', 'N02.4... | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of individual patient risk, centre, surgeon and anaesthetist on length of stay in hospital after cardiac surgery: Association of Cardiothoracic Anaesthesia and Critical Care (ACTACC) consecutive cases series study of 10 UK specialist centres. | OBJECTIVES: To determine the relative contributions of patient risk profile, local and individual clinical practice on length of hospital stay after cardiac surgery.DESIGN: Ten-year audit of prospectively collected consecutive cardiac surgical cases. Case-mix adjusted outcomes were analysed in models that included rand... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anesthesia, Cardiac Procedures', 'Anesthetists', 'Cardiac Surgical Procedures', 'Consultants', 'Female', 'Hospitals', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Risk Factors', 'Surgeons', 'United Kingdom... | 28,893,748 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E03.155.403'], ['M01.526.485.140', 'N02.360.140'], ['E04.100.376', 'E04.928.220'], ['M01.120'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['C23.550.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[blaVIM-2 gene detection in metallo-beta-lactamase-producing Pseudomonas aeruginosa strains isolated in an intensive care unit in Ciudad Bol?var, Venezuela]. | Ten Pseudomonas aeruginosa strains with resistance to broad-spectrum cephalosporin and carbapenems were studied to determine the presence of genes that mediate the production of metallo-beta-lactamases. These strains were isolated from patients with nosocomial infection at the Intensive Care Unit of the Complejo Hospit... | ['Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Child', 'Child, Preschool', 'Cross Infection', 'Disk Diffusion Antimicrobial Tests', 'Drug Resistance, Bacterial', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Phenotype', 'Polymerase Chain Reaction', 'Pseudomonas Infections', 'Pseudomonas aerugin... | 19,802,400 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['M01.060.406'], ['M01.060.406.448'], ['C01.248', 'C23.550.291.875.500'], ['E01.370.225.875.595.399', 'E05.200.875.595.399'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reaction of malondialdehyde (MDA) with alpha-N-acetylhistidine in the presence of alkanal. | The reaction of malondialdehyde (MDA) with alpha-N-acetyl-histidine (Ac-His) in the presence of alkanal was investigated. MDA alone did not react with Ac-His but when alkanal was present, a reaction took place. A similar result was obtained for the reaction of MDA with imidazole in the presence of alkanal. In addition,... | ['Aldehydes', 'Histidine', 'Hydrogen-Ion Concentration', 'Imidazoles', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Malondialdehyde'] | 8,069,270 | [['D02.047'], ['D12.125.072.329', 'D12.125.142.308'], ['G02.300'], ['D03.383.129.308'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['D02.047.700']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical and morphologic stages in Balkan endemic nephropathy]. | The first clinical classification of Balkan endemic nephropathy was elaborated by A. Puhlev et al in 1960, according to which two stages could be established in the course of the disease-compensated and decompensated. Gradually, many new data accumulated as regards the various aspects of the disease, that cannot be put... | ['Adolescent', 'Adult', 'Balkan Nephropathy', 'Humans', 'Kidney', 'Kidney Failure, Chronic', 'Kidney Glomerulus', 'Kidney Tubules, Proximal', 'Middle Aged', 'Nephritis, Interstitial'] | 6,673,348 | [['M01.060.057'], ['M01.060.116'], ['C12.777.419.570.643.150', 'C13.351.968.419.570.643.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['A05.810.453.736.560.570'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. | BACKGROUND: Neuropeptide Y (NPY) is a hypothalamic neuropeptide that plays a prominent role in feeding and energy homeostasis. Expression of the NPY Y1 receptor (Y1R) is highly concentrated in the nucleus accumbens (Acb), a region important in the regulation of palatable feeding. In this study, we performed a number of... | ['Action Potentials', 'Animals', 'Arcuate Nucleus of Hypothalamus', 'Choice Behavior', 'Corpus Striatum', 'Dietary Fats', 'Dietary Sucrose', 'Dynorphins', 'Eating', 'Enkephalins', 'Feeding Behavior', 'Male', 'Mice, Inbred C57BL', 'Neurons', 'Neuropeptide Y', 'Nucleus Accumbens', 'Protein Precursors', 'RNA, Messenger', ... | 25,109,664 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['F02.463.785.373.346'], ['A08.186.211.200.885.287.249.487'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.301.831.250', 'D09.698.629.305.770.200', 'D09.947.500.250', 'D09... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evaluating DCA-based method performances for RNA contact prediction by a well-curated data set. | RNA molecules play many pivotal roles in a cell that are still not fully understood. Any detailed understanding of RNA function requires knowledge of its three-dimensional structure, yet experimental RNA structure resolution remains demanding. Recent advances in sequencing provide unprecedented amounts of sequence data... | ['Data Analysis', 'Datasets as Topic', 'Nucleic Acid Conformation', 'RNA', 'Sequence Alignment'] | 32,276,988 | [['H01.548.338'], ['E05.318.308.056', 'L01.313.500.750.300.188.400.500', 'L01.399.250.224', 'L01.470.750.750.431', 'N05.715.360.300.224', 'N06.850.520.308.056'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735'], ['E05.393.751']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Exposure-response relationship of bronchial mucociliary clearance in rabbits following acute inhalations of sulfuric acid mist. | Eight rabbits underwent 1 h oral inhalations of submicrometer sulfuric acid mist at concentrations ranging from approx. 100-1084 micrograms/m3, followed by measurement of the mucociliary clearance of a tracer aerosol from the bronchial tree. These data, plus those from a previous study, were used to construct an exposu... | ['Aerosols', 'Animals', 'Bronchi', 'Dose-Response Relationship, Drug', 'Methods', 'Mucous Membrane', 'Rabbits', 'Sulfuric Acids'] | 6,474,515 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['A04.411.125'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.581'], ['A10.615.550'], ['B01.050.150.900.649.313.968.700'], ['D01.029.260.877.800', 'D01.875.800.800', 'D02.886.645.655']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New records, notes and new synonymies in American Cerambycidae (Coleoptera). | New country records are provided for Caperonotus superbus (Aurivillius, 1897), Heterachthes picturatus Martins, 1970, Neocompsa macrotricha Martins, 1970, Neocompsa spinosa Martins, 1970, Helvina strandi (Breuning, 1942), Bebelis furcula (Bates, 1880), and Bebelis longipennis (Bates, 1885). New state records are provid... | ['Animals', 'Coleoptera', 'United States'] | 33,056,546 | [['B01.050'], ['B01.050.500.131.617.720.500.500.375'], ['Z01.107.567.875']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Fuchsin acid selectively inhibits human immunodeficiency virus (HIV) replication in vitro. | Fuchsin acid, an anionic dye, is a selective inhibitor of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) in vitro. Its 50% effective dose for inhibition of HIV-1-induced cytopathogenicity in MT-4 cells and HIV-1 antigen expression in HUT-78 cells is 42 and 16 microM, respectively. These values are compa... | ['Animals', 'Antiviral Agents', 'Cell Line', 'Cytopathogenic Effect, Viral', 'Human T-lymphotropic virus 1', 'Human T-lymphotropic virus 2', 'Rosaniline Dyes', 'Virus Replication'] | 3,178,818 | [['B01.050'], ['D27.505.954.122.388'], ['A11.251.210'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B04.613.807.200.730.399', 'B04.820.650.200.730.404'], ['D02.092.146.755'], ['G06.920.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
'Dry' skin in atopic dermatitis. I. A clinical study. | A common finding in patients with atopic dermatitis is the occurrence of 'dry' skin on non-eczematous regions. 'Dry' skin is here defined as a clinical condition meaning a rough, finely scaling non-inflamed skin surface. The frequency and extension of 'dry' skin were examined in 50 patients with atopic dermatitis and w... | ['Adolescent', 'Adult', 'Animals', 'Back', 'Dermatitis, Atopic', 'Female', 'Humans', 'Male', 'Microscopy, Electron, Scanning', 'Seasons', 'Skin', 'Wool'] | 2,568,049 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['A01.923.176'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.2... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biodegradable near-infrared-photoresponsive shape memory implants based on black phosphorus nanofillers. | In this paper, we propose a new shape memory polymer (SMP) composite with excellent near-infrared (NIR)-photoresponsive shape memory performance and biodegradability. The composite is fabricated by using piperazine-based polyurethane (PU) as thermo-responsive SMP incorporated with black-phosphorus (BP) sheets as NIR ph... | ['Absorbable Implants', 'Animals', 'Biocompatible Materials', 'Female', 'Humans', 'Mice', 'Nanostructures', 'Phosphorus'] | 29,477,708 | [['E07.695.025'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['J01.637.512'], ['D01.268.666']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinical usefulness of tissue Doppler imaging in predicting preclinical Fabry cardiomyopathy. | UNLABELLED: Fabry cardiomyopathy (FC) is characterized by left ventricular hypertrophy (LVH). The aim of this study is to determine whether early changes revealed by tissue Doppler imaging (TDI) are useful for detecting preclinical cardiac abnormalities in patients with this X-linked genetic disorder. If so, this tool ... | ['Adult', 'Area Under Curve', 'Cardiomyopathies', 'Case-Control Studies', 'Echocardiography, Doppler', 'Fabry Disease', 'Female', 'Humans', 'Hypertrophy, Left Ventricular', 'Linear Models', 'Male', 'Mass Screening', 'Prevalence', 'Prospective Studies', 'ROC Curve', 'Sensitivity and Specificity', 'Statistics as Topic', ... | 18,691,784 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['C14.280.238'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['C10.228.140.163.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Proteolytic conversion of neurohypophyseal peptides by rat thymocytes: involvement of endopeptidases. | The proteolytic conversion of oxytocin and Arg8-vasopressin by purified rat thymocytes was studied at 37 degrees C and physiological pH 7.4. The formed peptide fragments were isolated by high performance liquid chromatography and characterized by amino acid analysis. When oxytocin was incubated with rat thymocytes, oxy... | ['Amino Acids', 'Animals', 'Arginine Vasopressin', 'Chromatography, High Pressure Liquid', 'Endopeptidases', 'Neuropeptides', 'Oxytocin', 'Peptide Hydrolases', 'Pituitary Gland, Posterior', 'Rats', 'Thymus Gland'] | 1,641,073 | [['D12.125'], ['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['E05.196.181.400.300'], ['D08.811.277.656.300'], ['D12.644.400', 'D12.776.631.650'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['D08.811.277.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Involvement of intrahepatic innervation in caesium-induced haemodynamic oscillations in the rat liver. | 1. Cs+ was used to study the mechanisms involved in the induction of haemodynamic and metabolic oscillations in the isolated rat liver perfused by the portal vein. 2. Cs+ (2.25 mM) in K(+)-free perfusate causes the appearance of periodic increases in portal pressure (3.87 +/- 0.6 mmHg, n = 24) and decreases in O2 uptak... | ['Animals', 'Cesium', 'Egtazic Acid', 'Liver', 'Male', 'Oxygen', 'Perfusion', 'Portal Pressure', 'Potassium', 'Rats', 'Rats, Sprague-Dawley', 'Regional Blood Flow', 'Tetrodotoxin', 'Verapamil'] | 8,487,213 | [['B01.050'], ['D01.268.549.125', 'D01.268.556.165', 'D01.552.528.160', 'D01.552.544.165'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['A03.620'], ['D01.268.185.550', 'D01.362.670'], ['E05.680'], ['G09.330.380.076.732.650'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Psychopharmaceutical drugs in the mass media. Results of a systematic analysis of text contents and images]. | Mental diseases and psychopharmacological drugs are frequently discussed in newspapers and popular magazines. The representations are supposed to have a great impact on people's opinions on the subject. From 1 August 1991 to 31 July 1992 all articles about psychopharmacological drugs and cardiac drugs in 19 German news... | ['Cardiovascular Agents', 'Drug Utilization', 'Germany', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Mental Disorders', 'Newspapers as Topic', 'Psychotherapy', 'Psychotropic Drugs', 'Public Opinion', 'Treatment Outcome'] | 8,532,100 | [['D27.505.954.411'], ['N04.452.706.477'], ['Z01.542.315'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['L01.178.682.829.481'], ['F04.754'], ['D27.505.954.427.700'], ['I01.880.630.548'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Cyclic vomiting syndrome versus inborn errors of metabolism: A review with clinical recommendations. | BACKGROUND: Inborn errors of metabolism are on the differential for patients presenting with a cyclic vomiting syndrome phenotype. Classes of disorders to consider include: mitochondrial disorders, fatty acid oxidation disorders, urea cycle defects, organic acidurias, and acute intermittent porphyria.AIM: This article ... | ['Humans', 'Lipid Metabolism, Inborn Errors', 'Phenotype', 'Vomiting'] | 26,678,622 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.398', 'C18.452.584.562', 'C18.452.648.398'], ['G05.695'], ['C23.888.821.937']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphologic Overlap between Infantile Myofibromatosis and Infantile Fibrosarcoma: A Pitfall in Diagnosis. | Infantile myofibromatosis (IM) is a distinctive mesenchymal disorder with different clinical forms, including solitary, multicentric, and generalized with visceral involvement. A wide morphologic spectrum is encountered, with the extremes resembling congenital infantile fibrosarcoma (CIFS) and infantile hemangiopericyt... | ['Actins', 'Antigens, CD34', 'Chromosomes, Human, Pair 12', 'Chromosomes, Human, Pair 15', 'DNA, Complementary', 'Diagnosis, Differential', 'Female', 'Fibrosarcoma', 'Humans', 'Immunohistochemistry', 'Infant', 'Infant, Newborn', 'Male', 'Myofibromatosis', 'Oncogene Proteins, Fusion', 'RNA, Neoplasm', 'Reverse Transcrip... | 19,006,426 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['A11.284.187.520.300.325.360', 'G05.360.162.520.300.325.360'], ['A11.284.187.520.300.370.385', 'G05.360.162.520.300.370.385'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The adenosine receptor blocker aminophylline increases anoxic ethanol excretion in crucian carp. | By depressing energy consumption, anoxia-tolerant animals are thought to compensate for a reduced ability to produce energy during anoxia. Adenosine is an inhibitory neuromodulator in vertebrates and, hence, has the potential ability to depress energy consumption. Ethanol is the main metabolic end product in anoxic Car... | ['Aminophylline', 'Animals', 'Carps', 'Ethanol', 'Hypoxia', 'Oxygen Consumption', 'Purinergic Antagonists'] | 1,928,423 | [['D02.092.782.258.368.050', 'D03.633.100.759.758.824.751.075', 'D26.310.048'], ['B01.050'], ['B01.050.150.900.493.200.244.248'], ['D02.033.375'], ['C23.888.852.079'], ['G03.680'], ['D27.505.519.625.725.400', 'D27.505.696.577.725.400']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice. | The impairment of cytotoxic activity of lymphocytes disturbs immune surveillance and leads to the development of hemophagocytic lymphohistiocytic syndrome (HLH). Although cytotoxic T lymphocyte (CTL) control of HLH development is well documented, the role for natural killer (NK)-cell effector functions in the pathogene... | ['Animals', 'Cell Proliferation', 'Cells, Cultured', 'Cytotoxicity, Immunologic', 'Interferon-gamma', 'Killer Cells, Natural', 'Lymphocytic Choriomeningitis', 'Lymphocytic choriomeningitis virus', 'Lymphohistiocytosis, Hemophagocytic', 'Mice', 'Mice, Inbred C57BL', 'Spleen', 'T-Lymphocytes, Cytotoxic', 'Viral Load'] | 25,525,117 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G12.287'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of T-2 toxin on induction of petite mutants and mitochondrial function in Saccharomyces cerevisiae. | The influence of the trichothecene mycotoxin T-2 on the mitochondria of Saccharomyces cerevisiae was studied. T-2 is a cytotoxic molecule inhibiting growth and macromolecular synthesis in S. cerevisiae. At low concentrations, T-2 toxin arrested yeast growth on glycerol medium and at higher concentrations, it arrested g... | ['Cell Division', 'Ethidium', 'Genes, Fungal', 'Mitochondria', 'Mutation', 'Saccharomyces cerevisiae', 'Sesquiterpenes', 'T-2 Toxin'] | 3,329,043 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D03.633.300.633.416'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.365.590'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D02.455.84... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of partition coefficients for selected polycyclic aromatic hydrocarbons between isolated plant cuticles and water. | Partition coefficients between plant cuticles and water (Kcutw) were measured for 10 selected polycyclic aromatic hydrocarbons (PAHs) to evaluate the sorption capacity of plant cuticular layers for hydrophobic organic chemicals. The partitioning properties of PAHs between cuticles and water were evaluated by using (1) ... | ['Environmental Monitoring', 'Fresh Water', 'Hydrophobic and Hydrophilic Interactions', 'Plants', 'Polycyclic Aromatic Hydrocarbons', 'Water Pollutants, Chemical'] | 25,038,429 | [['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.280', 'N06.230.232'], ['G02.409'], ['B01.650'], ['D02.455.426.559.847', 'D04.615'], ['D27.888.284.903.655']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Validating the effect of muscle artifact suppression in localizing focal epilepsy. | Source localization of an epileptic seizure is becoming an important diagnostic tool in pre-surgical evaluation of epileptic patients. However, for localizing the epileptogenic zone precisely, the epileptic activity needs to be isolated from other activities that are not related to the epileptic source. In this study, ... | ['Algorithms', 'Artifacts', 'Brain', 'Electroencephalography', 'Epilepsies, Partial', 'Humans', 'Models, Biological', 'Muscles'] | 25,570,829 | [['G17.035', 'L01.224.050'], ['E05.047'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['A02.633', 'A10.690']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
C-arm computed tomography parenchymal blood volume measurement in evaluation of hepatocellular carcinoma before transarterial chemoembolization with drug eluting beads. | BACKGROUND: C-arm computed tomography (CT) guided intervention is an increasingly applied technique in transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC). The aim of this study was to analyse the value of parenchymal blood volume (PBV) maps acquired during C-arm CT acquisition, for pre-treatment e... | ['Aged', 'Anatomy, Cross-Sectional', 'Antineoplastic Agents', 'Blood Volume', 'Carcinoma, Hepatocellular', 'Chemoembolization, Therapeutic', 'Feasibility Studies', 'Female', 'Humans', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Neovascularization, Pathologic', 'Retrospec... | 26,715,200 | [['M01.060.116.100'], ['H01.158.100.185'], ['D27.505.954.248'], ['G09.188.130', 'G09.330.380.092'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.520.360.150', 'E02.926.500.150'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.05... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Association between the disability prevention program "Secondary Preventive Services" and disability incidence among the elderly population: A nationwide longitudinal comparison of Japanese municipalities. | AIM: The aim of the present ecological study was to evaluate the relationship between the rate of participation in Secondary Preventive Services (SPS) and the incidence of disability in Japanese municipalities.METHODS: We used the national statistics data for Long-term Care Insurance (LTCI), because all Japanese people... | ['Aged', 'Aged, 80 and over', 'Disability Evaluation', 'Disabled Persons', 'Female', 'Geriatric Assessment', 'Humans', 'Incidence', 'Insurance, Long-Term Care', 'Japan', 'Longitudinal Studies', 'Male', 'Patient Acceptance of Health Care', 'Secondary Prevention'] | 25,597,858 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.400'], ['M01.150'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Isolation of human cDNA clones of myb-related genes, A-myb and B-myb. | cDNA clones of the myb-related genes A-myb and B-myb were obtained by screening human cDNA libraries. The predicted open reading frame of B-myb could encode a protein of 700 amino acid residues. Although the C-terminal end has not been cloned yet, an almost entire coding region of A-myb, which is 745 amino acid long, w... | ['Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'DNA', 'Humans', 'Molecular Sequence Data', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-myb', 'Proto-Oncogenes', 'RNA, Messenger', 'Sequence Homology, Nucleic Acid'] | 3,060,855 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.776.624.664.700'], ['D12.776.260.675', 'D12.776.624.664.700.188', 'D12.776.930.725'], ['G05.360.340.024.34... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The correlating factors affecting nursing personnel resignation in an university hospital]. | Demographic characteristics of 1080 university hospital nursing personnel were studied from January 1979 to December 1987. These characteristics included age, marital status, number of children and educational background. Among them, 457 nurses have resigned, while others remain in service. We evaluated the correlation... | ['Adult', 'Employment', 'Female', 'Hospitals, University', 'Humans', 'Nursing', 'Taiwan', 'Workforce'] | 2,243,374 | [['M01.060.116'], ['N01.824.245'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478', 'N04.452.758.377'], ['Z01.252.474.872', 'Z01.639.850'], ['N04.452.525']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
First clinical implantation of the BCM 3.5 ventricular assist device (VAD). | We report on the first human implantation of the BCM 3.5 ventricular assist device in a 46-year-old man suffering from terminal stage cardiomyopathy. The circulatory support was used as a bridge to heart transplantation. The patient was in cardiogenic shock and was on assisted circulation for 18 days after which he und... | ['Cardiomyopathy, Dilated', 'Electrocardiography', 'Equipment Design', 'Heart Failure', 'Heart Transplantation', 'Heart-Assist Devices', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged'] | 2,018,649 | [['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.320'], ['C14.280.434'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Utilization of serologic assays to support efficacy of vaccines in nonclinical and clinical trials: meeting at the crossroads. | In May 2009 the National Institute of Allergy and Infectious Diseases hosted a workshop on serologic assays that support vaccine efficacy evaluations. The meeting promoted exchange of ideas among investigators from varying disciplines who are working on anti-infectious agent vaccines at different stages of development.... | ['Immunoassay', 'Vaccines'] | 20,470,795 | [['E05.478.566', 'E05.601.470'], ['D20.215.894']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Management of emergency vs. otorhinolaryngology department tracheobronchial foreign-body aspiration]. | Foreign-body aspiration (FBA) obstructing the airways may lead to choking and cardiopulmonary arrest without immediate emergency care. We retrospectively reviewed medical records of 17 otorhinolaryngology subjects-8 men and 9 women aged 0 to 84 years-88% of whom were < 3 years old, requiring tracheobronchial FBA betwee... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bronchi', 'Child', 'Child, Preschool', 'Emergency Service, Hospital', 'Female', 'Foreign Bodies', 'Hospital Departments', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Otolaryngology', 'Trachea'] | 19,894,592 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A04.411.125'], ['M01.060.406'], ['M01.060.406.448'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['C26.392'], ['N02.278.216.500.968', 'N04.452.442.452.422'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid discrimination of Listeria monocytogenes strains by microtemperature gradient gel electrophoresis. | Microtemperature gradient gel electrophoresis (mu-TGGE) was examined for use for the rapid subtyping of Listeria monocytogenes strains. Comparison of genomes between L. monocytogenes strains F2365 and H7858 identified a sequence encoding a portion of the PRT/PTS system IIA 2 protein domain as appropriate for mu-TGGE an... | ['Animals', 'Bacterial Typing Techniques', 'Cheese', 'Chickens', 'DNA, Bacterial', 'Electrophoresis, Agar Gel', 'Food Microbiology', 'Guinea Pigs', 'Humans', 'Listeria monocytogenes', 'Meat', 'Meat Products', 'Molecular Sequence Data', 'Rabbits', 'Sequence Analysis, DNA', 'Temperature', 'Time Factors'] | 16,757,621 | [['B01.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G07.203.200.500.444', 'G07.203.300.350.300.444', 'J02.350.500.444', 'J02.500.350.300.444'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.444.308.212'], ['E05.196.401.153', 'E05.301.300.100'], ['H01.158.273.540.274.332', 'J01.57... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration. | To determine the effectiveness of hemoglobin A1c (HbA1c) ? 6.5% in diagnosing diabetes compared to fasting plasma glucose (FPG) ? 126 mg/dL and 2-hour plasma glucose (2hPG) ? 200 mg/dL in a previously undiagnosed diabetic cohort, we included 5,764 adult subjects without established diabetes for whom HbA1c, FPG, 2hPG, a... | ['Adult', 'Aged', 'Blood Glucose', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Fasting', 'Female', 'Glucose Tolerance Test', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Middle Aged', 'Nutrition Surveys'] | 27,597,979 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.35... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative studies on eosinophil chemotactic factors during leukocyte migration under agarose. | Several known eosinophil chemotactic factors are compared with regard to their biological behavior during in vitro migration under agarose: zymosan activated serum (Zas), containing the chemotactic fragment C5a, the lymphokine eosinophil stimulation promoter (ESP), neutrophil-derived eosinophil chemotactic factor (ECF)... | ['Chemotactic Factors', 'Chemotactic Factors, Eosinophil', 'Dipeptides', 'Eosinophils', 'Humans', 'Kinetics', 'Leukocytes', 'Lymphokines', 'Neutrophils', 'Sepharose', 'Zymosan'] | 7,130,738 | [['D23.125'], ['D23.125.320'], ['D12.644.456.345'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['D12.644.276.374.480', 'D12.776.467.374.4... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Locoregional recurrence after preoperative radiation therapy for retroperitoneal sarcoma: adverse impact of multifocal disease and potential implications of dose escalation. | BACKGROUND: Locoregional recurrence (LRR) rates following preoperative radiation therapy (RT) and radical resection for retroperitoneal sarcoma (RPS) are high. Targeted radiation dose escalation has been proposed as a means to decrease LRR, but is applicable only if LRRs are confined to within the RT field. We analyzed... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brachytherapy', 'Disease-Free Survival', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoadjuvant Therapy', 'Neoplasm Recurrence, Local', 'Neoplasms, Multiple Primary', 'Radiotherapy Dosage', 'Radiotherapy, Adjuvant', 'Radiotherapy, Image-Gui... | 23,392,853 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.815.150'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Physiology of the lower urinary tract. | This article presents the concepts that give meaning to the pressures observed in the various parts of the body occurring normally and abnormally in various conditions. Normal pressure relationships, holding urine, voiding, incontinence, and flatulence and defecation are discussed. | ['Defecation', 'Flatulence', 'Humans', 'Urethra', 'Urinary Bladder', 'Urinary Incontinence, Stress', 'Urination', 'Urodynamics'] | 8,659,019 | [['G10.261.165'], ['C23.888.821.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.444.492.726', 'A05.810.876'], ['A05.810.890'], ['C12.777.934.852.249', 'C13.351.968.934.814.500', 'C23.888.942.343.800.500'], ['G08.852.880'], ['G08.852.898']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Soluble CD16 in the treatment of murine lupus nephritis. | To determine if soluble CD16 (sCD16) could alter the expression of lupus-like disease, groups of 10 female NZB/NZW mice (age 16-20 weeks) were given sCD16 three times a week for 5 weeks (control; 100 microg; 200 microg/dose) after onset of proteinuria. Results of this study indicate that the administration of sCD16 aft... | ['Animals', 'Antibodies, Antinuclear', 'Female', 'Immunoglobulin G', 'Lupus Nephritis', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred NZB', 'Proteinuria', 'Receptors, IgG', 'Solubility'] | 9,683,555 | [['B01.050'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['C12.777.419.570.363.680', 'C13.351.968.419.570.363.680', 'C17.300.480.680', 'C20.111.590.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Kinetic model of ethopropazine interaction with horse serum butyrylcholinesterase and its docking into the active site. | The action of a potent tricyclic cholinesterase inhibitor ethopropazine on the hydrolysis of acetylthiocholine and butyrylthiocholine by purified horse serum butyrylcholinesterase (EC 3.1.1.8) was investigated at 25 and 37 degrees C. The enzyme activities were measured on a stopped-flow apparatus and the analysis of ex... | ['Animals', 'Binding Sites', 'Binding, Competitive', 'Butyrylcholinesterase', 'Cholinergic Antagonists', 'Horses', 'Kinetics', 'Phenothiazines'] | 11,811,945 | [['B01.050'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D08.811.277.352.100.170.250'], ['D27.505.519.625.120.200', 'D27.505.696.577.120.200'], ['B01.050.150.900.649.313.984.235.472'], ['G01.374.661', 'G02.111.490'], ['D02.886.369', 'D03.633.300.783']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A controlled comparison of the efficacy of clomiphene citrate in male infertility. | To determine whether clomiphene citrate (CC) improves fertility in oligospermic men, 23 men with sperm concentrations between 0.5 and 20 million sperm per milliliter; normal serum gonadotropins and testosterone; and a presumptively fertile partner were enrolled in the study. After a 3-month control period, patients wer... | ['Clomiphene', 'Estradiol', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Humans', 'Infertility, Male', 'Luteinizing Hormone', 'Male', 'Semen', 'Sperm Count', 'Testosterone'] | 3,129,318 | [['D02.455.426.559.389.150.700.125'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Consultant duration of clinical practice as a cost determinant of an emergency medical admission. | BACKGROUND: Little data exists relating years of hospital consultant work experience, from time of consultant certification, and costs incurred for emergency medical patients under their care. We examined the total cost of emergency medical episodes in relation to certified consultant years experience using a database ... | ['Adult', 'Age Factors', 'Aged', 'Consultants', 'Emergency Service, Hospital', 'Female', 'Hospital Costs', 'Hospital Mortality', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Time Factors'] | 25,005,790 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.120'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Research activity and capacity in primary healthcare: the REACH study: a survey. | BACKGROUND: Despite increased investment in primary care research and development (R&D), the level of engagement of primary healthcare professionals with research remains poor. The aim of this study is to assess the level of research activity and capacity for research among primary healthcare professionals in a health ... | ['Adult', 'Analysis of Variance', 'Attitude of Health Personnel', 'Data Collection', 'Evidence-Based Medicine', 'Female', 'Health Personnel', 'Health Services Research', 'Humans', 'Male', 'Middle Aged', 'Primary Health Care', 'Research Design'] | 19,432,990 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.050', 'N05.300.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['H02.249.750', 'H02.403.200.400'], ['M01.526.485', 'N02.360'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Cytology of pleomorphic lobular carcinoma with apocrine cell differentiation of the breast. A case report. | BACKGROUND: Pleomorphic lobular carcinoma (PLC) with apocrine differentiation is a rare breast carcinoma, and its cytologic findings have not been reported before.CASE: A 75-year-old woman had a mass in and skin rash on the left breast. Apocrine carcinoma was suggested on aspiration cytology of the mass. The cytologic ... | ['Aged', 'Apocrine Glands', 'Apolipoproteins', 'Apolipoproteins D', 'Biomarkers, Tumor', 'Breast', 'Breast Neoplasms', 'Carcinoma, Lobular', 'Carrier Proteins', 'Cell Differentiation', 'Cell Nucleus', 'Female', 'Glycoproteins', 'Humans', 'Immunohistochemistry', 'Membrane Transport Proteins', 'Muramidase'] | 12,685,199 | [['M01.060.116.100'], ['A10.336.899.206', 'A17.815.830.206'], ['D10.532.091', 'D12.776.070.400', 'D12.776.521.120'], ['D10.532.091.450', 'D12.776.070.400.450', 'D12.776.521.120.450'], ['D23.101.140'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.180.437', ... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Baseline Predictors of Singular Action Among Participants With Multiple Health Behavior Risks. | PURPOSE: Previous studies found that treatment effects can change two behaviors, but not one. This study examined baseline transtheoretical model constructs as three alternative predictors (stage of change, effort, and severity) of singular action among participants with co-occurring health behavior risks.DESIGN: The s... | ['Adult', 'Diet', 'Female', 'Health Promotion', 'Health Risk Behaviors', 'Humans', 'Logistic Models', 'Male', 'Smoking', 'Smoking Prevention', 'Sunburn'] | 27,404,645 | [['M01.060.116'], ['G07.203.650.240'], ['I02.233.332.445', 'N02.421.726.407.579'], ['F01.145.488.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
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