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Gastrointestinal tuberculosis as a cause of massive bleeding. | BACKGROUND: Although minor bleeding is fairly common among cases of gastrointestinal tuberculosis, massive hemorrhage necessitating blood transfusion is rare.CASE REPORT: A 72-year-old woman presented to the hospital with hematochezia. Colonoscopy revealed multiple ulcers, including round ulcers, throughout the large i... | ['Aged', 'Colonoscopy', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Mycobacterium tuberculosis', 'Radiography', 'Radionuclide Imaging', 'Tuberculosis, Gastrointestinal'] | 19,789,515 | [['M01.060.116.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['E01.370.350.700'], ['E01.370.350.710'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
No evidence for â cell neogenesis in murine adult pancreas. | Whether facultative â cell progenitors exist in the adult pancreas is a major unsolved question. To date, lineage-tracing studies have provided conflicting results. To track â cell neogenesis in vivo, we generated transgenic mice that transiently coexpress mTomato and GFP in a time-sensitive, nonconditional Cre-mediate... | ['Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Cell Proliferation', 'Cell Separation', 'Female', 'Flow Cytometry', 'Green Fluorescent Proteins', 'Immunohistochemistry', 'Inflammation', 'Insulin', 'Insulin-Secreting Cells', 'Mice', 'Mice, Transgenic', 'Microscopy, Fluorescence', 'Nerve Tissue Proteins', 'P... | 23,619,362 | [['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Inpatient glycemic management in internal medicine: an observational multicenter study in Nanjing, China. | AIMS: To evaluate the prevalence of hyperglycemia among inpatients in internal medicine, and specifically, to assess the glycemic management of inpatients in non-endocrinology departments in three large urban hospitals in China.METHODS: A multicenter observational study was conducted using electronic health records, an... | ['Adolescent', 'Adult', 'Aged', 'Blood Glucose', 'China', 'Diabetes Mellitus', 'Electronic Health Records', 'Female', 'Hospitalization', 'Hospitals', 'Humans', 'Hyperglycemia', 'Hypoglycemia', 'Inpatients', 'Internal Medicine', 'Male', 'Middle Aged', 'Prevalence', 'Surveys and Questionnaires', 'Young Adult'] | 28,504,012 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['Z01.252.474.164'], ['C18.452.394.750', 'C19.246'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Green tea (Camellia sinensis) administration induces expression of immune relevant genes and biochemical parameters in rainbow trout (Oncorhynchus mykiss). | Present study elucidates the efficacy of green tea (Camellia sinensis) on growth performance, immune and antioxidant systems and cytokine gene expression in rainbow trout tissues. Green tea was supplemented at 20, 100, and 500 mg kg(-1) diet and fed to fish (average weight: 23.5 g) for 35 days. No remarkable changes in... | ['Animal Feed', 'Animals', 'Camellia sinensis', 'Diet', 'Dietary Supplements', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation', 'Interleukins', 'Kidney', 'Liver', 'Oncorhynchus mykiss', 'Organ Specificity', 'Plant Leaves', 'Real-Time Polymerase Chain Reaction', 'Spleen', 'Tumor Necrosis Factor-alpha', ... | 24,096,104 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.650.940.800.575.912.250.341.998.500.500'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['A05.810.453'], ['A03.620'], ['B01.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Glycometabolic reprogramming associated with the initiation of human dental pulp stem cell differentiation. | Glycometabolism, particularly mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis, plays a central role in cell life activities. Glycometabolism can be reprogrammed to maintain the stemness or to induce the differentiation of stem cells, thereby regulating tissue repair and regeneration. However, research o... | ['Adolescent', 'Cell Differentiation', 'Cell Hypoxia', 'Cells, Cultured', 'Cellular Reprogramming', 'Dental Pulp', 'Glycolysis', 'Hexokinase', 'Humans', 'L-Lactate Dehydrogenase', 'Mitochondria', 'Oxidative Phosphorylation', 'Pyruvate Kinase', 'Stem Cells', 'Young Adult'] | 26,634,800 | [['M01.060.057'], ['G04.152'], ['G03.197.300', 'G04.270.300'], ['A11.251'], ['G04.152.262', 'G05.135'], ['A14.549.167.900.260'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['D08.811.913.696.620.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.047.551.400', 'D08.811.682.047.82... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cultural interrelationships and the lived experience of Pakistani breast cancer patients. | AIM: There is a paucity of British and international literature on the psychological, sociological and cultural correlates of breast health in ethnic minority women.METHODS: This two centre qualitative study was part of a larger study that aimed to examine the influence of culture on the lived experience of Pakistani M... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Attitude to Health', 'Breast Neoplasms', 'Cross-Cultural Comparison', 'Emigrants and Immigrants', 'Female', 'Humans', 'Interpersonal Relations', 'Islam', 'London', 'Middle Aged', 'Nursing Methodology Research', 'Pakistan', 'Qualitative Research', 'Residence Characteristic... | 20,584,625 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['C04.588.180', 'C17.800.090.500'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['M01.189'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['K01.844.275'], ['Z01.433.553', 'Z01.542.363.300.553'], ['M01.060.116.63... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phe... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Fractionating controlled memory processes and recall of context in recognition memory: a case report. | Recollection has been described as both a recognition memory judgment requiring cognitive control and the ability to retrieve contextual information about a prior occurrence. At the core of this article is the question whether or not these two subcomponents of recollection are dissociable in amnesia. In three experimen... | ['Adolescent', 'Amnesia, Anterograde', 'Executive Function', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Recall', 'Neuropsychological Tests', 'Recognition, Psychology'] | 28,859,551 | [['M01.060.057'], ['C10.597.606.525.100.075', 'C23.888.592.604.529.100.075', 'F01.700.625.100.075', 'F03.615.200.137'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.425.540.641'], ['F04.711.513'], ['F02.463.425.540.706']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Selective suppression of harmful cyanobacteria in an entire lake with hydrogen peroxide. | Although harmful cyanobacteria form a major threat to water quality, few methods exist for the rapid suppression of cyanobacterial blooms. Since laboratory studies indicated that cyanobacteria are more sensitive to hydrogen peroxide (H(2)O(2)) than eukaryotic phytoplankton, we tested the application of H(2)O(2) in natu... | ['Cyanobacteria', 'Eutrophication', 'Fresh Water', 'Hydrogen Peroxide', 'Lakes', 'Microcystins', 'Netherlands', 'Water Purification', 'Water Quality'] | 22,112,924 | [['B03.280', 'B03.440.475.100'], ['G16.500.285'], ['G16.500.275.280', 'N06.230.232'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D04.345.566.447', 'D12.644.641.447', 'D23.946.123.574'], ['Z01.542.651'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Central hypotensive action of clonidine requires nitric oxide. | Background- Clonidine has an antihypertensive effect by its action in the brain and, because we observed that the tonic production of nitric oxide (NO) in the brain is required to maintain blood pressure at its low, normotensive level, the current study was designed to determine whether the hypotensive action of clonid... | ['Animals', 'Antihypertensive Agents', 'Biosensing Techniques', 'Blood Pressure', 'Brain', 'Clonidine', 'Electrochemistry', 'Enzyme Inhibitors', 'Heart Rate', 'In Vitro Techniques', 'Injections, Intraventricular', 'Male', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Rats', 'Rats, Sprague-D... | 11,602,488 | [['B01.050'], ['D27.505.954.411.162'], ['E05.601.043'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.186.211'], ['D03.383.129.308.436.500'], ['H01.181.529.307'], ['D27.505.519.389'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E05.481'], ['E02.319.267.530.550'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
CT findings in tuboovarian abscess. | Pelvic inflammatory disease with tuboovarian abscess can cause a wide range of radiologic abnormalities. Although the diagnosis of tuboovarian abscess is usually straightforward and is based on clinical and sonographic findings, unusual or unsuspected cases may be confused with other pelvic or abdominal diseases. The p... | ['Abscess', 'Diagnosis, Differential', 'Fallopian Tube Diseases', 'Female', 'Humans', 'Ovarian Diseases', 'Pelvis', 'Tomography, X-Ray Computed'] | 1,738,998 | [['C01.830.025', 'C23.550.470.756.100'], ['E01.171'], ['C13.351.500.056.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.056.630', 'C19.391.630'], ['A01.923.600'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The risk of stent thrombosis in the perioperative setting]. | Percutaneous coronary interventions associated with a need for long-term dual anti-platelet therapy are steadily increasing. Accordingly, reports of severe perioperative complications in this high-risk group of patients are also increasing. Complications can be categorized into two groups: coronary ischemia or myocardi... | ['Angioplasty, Balloon, Coronary', 'Cooperative Behavior', 'Coronary Restenosis', 'Coronary Thrombosis', 'Drug Therapy, Combination', 'Gastrointestinal Hemorrhage', 'Humans', 'Interdisciplinary Communication', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Nephrectomy', 'Patient Care Team', 'Perio... | 19,898,790 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['F01.145.813.115'], ['C14.280.647.250.285.200', 'C14.907.585.250.285.200'], ['C14.280.647.250.290', 'C14.907.355.830... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A path analysis of the effects of the doctor-patient encounter and expectancy in an open-label randomized trial of spinal manipulation for the care of low back pain. | BACKGROUND: The doctor-patient encounter (DPE) and associated patient expectations are potential confounders in open-label randomized trials of treatment efficacy. It is therefore important to evaluate the effects of the DPE on study outcomes.METHODS: Four hundred participants with chronic low back pain (LBP) were rand... | ['Adult', 'Chiropractic', 'Female', 'Health Personnel', 'Humans', 'Low Back Pain', 'Male', 'Manipulation, Chiropractic', 'Manipulation, Spinal', 'Massage', 'Physician-Patient Relations', 'Research Design', 'Treatment Outcome'] | 24,410,959 | [['M01.060.116'], ['H02.110'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['E02.190.599.233'], ['E02.779.867.466', 'E02.831.535.867.466'], ['E02.190.599.750.750', 'E02.779.867.880.750', 'E02.831.535.867.880.750'], ['F01.829.401.650.675', 'N05.300.660.625'],... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Bayesian Detection of Abnormal Asynchrony of Division Between Sister Cells in Mutant Caenorhabditis elegans | Cell division timing is critical for cell fate specification and morphogenesis during embryogenesis, but how division timings are regulated among cells during development is poorly understood. In this article, we focus on the comparison of asynchrony of division, that is, difference of lifetime, between sister cells (A... | ['Animals', 'Bayes Theorem', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Cell Differentiation', 'Cell Division', 'Embryo, Nonmammalian', 'Embryonic Development', 'Gene Expression Regulation, Developmental', 'Morphogenesis', 'Mutation'] | 30,964,328 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of in vivo and in vitro prostaglandin E2 production by squamous cell carcinoma of the head and neck. | Prostaglandin E2 has been identified as an immunosuppressive factor in patients with squamous cell carcinoma of the head and neck. Spontaneous prostaglandin E2 production by 21 cancer cell lines, which were obtained from 17 patients with squamous cell carcinoma of the head and neck, was determined by radioimmunoassay. ... | ['Aged', 'Aged, 80 and over', 'Blood', 'Carcinoma, Squamous Cell', 'Cell Line', 'Culture Media', 'Dinoprostone', 'Dose-Response Relationship, Drug', 'Head and Neck Neoplasms', 'Humans', 'Indomethacin', 'Keratinocytes', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Registries', 'Survival Rate', 'Time Factors'... | 8,084,624 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A12.207.152', 'A15.145'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210'], ['D27.720.470.305', 'E07.206'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['G07.690.773.875', 'G07.690.936.500'], ['C04.588.443'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical events after surgical splenectomy in children with sickle cell anemia. | PURPOSE: Despite advances in immune prophylaxis, sepsis remains the most feared complication following splenectomy for acute splenic sequestration crisis (ASSC) in children with sickle cell anemia (SCA). We seek to investigate the true prevalence of sepsis and other complications of splenectomy in this patient populati... | ['Acute Chest Syndrome', 'Adolescent', 'Anemia, Sickle Cell', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant', 'Laparoscopy', 'Male', 'Pain, Postoperative', 'Postoperative Complications', 'Prevalence', 'Risk Factors', 'Sepsis', 'Splenectomy', 'Statistics, Nonparametric', 'Str... | 20,309,565 | [['C08.381.074', 'C08.618.009', 'C15.378.071.141.150.150.219', 'C15.378.420.155.219', 'C16.320.070.150.219', 'C16.320.365.155.219'], ['M01.060.057'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Statin use is independently associated with smaller infarct volume in nonlacunar MCA territory stroke. | BACKGROUND: Studies have shown an association between HMG-CoA reductase inhibitors (statins) and improved stroke outcomes, possibly secondary to neuroprotective properties.OBJECTIVE: To assess whether patients taking statins prior to ischemic stroke have smaller infarcts on magnetic resonance imaging (MRI), adjusting f... | ['Aged', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Infarction, Middle Cerebral Artery', 'Male'] | 17,032,384 | [['M01.060.116.100'], ['E01.370.350.825.500.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['C10.228.140.300.150.477.200.450', 'C10.228.140.300.510.200.387', 'C10.228.140.300.775.200.200.450', 'C14.907.253.092.477.200.450', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evolution of simple multicellular life cycles in dynamic environments. | The mode of reproduction is a critical characteristic of any species, as it has a strong effect on its evolution. As any other trait, the reproduction mode is subject to natural selection and may adapt to the environment. When the environment varies over time, different reproduction modes could be optimal at different ... | ['Animals', 'Biological Evolution', 'Environment', 'Life Cycle Stages', 'Models, Biological', 'Reproduction', 'Selection, Genetic'] | 31,088,261 | [['B01.050'], ['G05.045', 'G16.075'], ['G16.500.275', 'N06.230'], ['B05.500', 'G07.345.500.550.500'], ['E05.599.395'], ['G08.686.784'], ['G05.783']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transplanted bone marrow stromal cells migrate, differentiate and improve motor function in rats with experimentally induced cerebral stroke. | Bone marrow stromal cells are multipotential cells that can be induced to differentiate into osteoblasts, chondrocytes, myocytes and adipocytes in different microenvironments. Recent studies revealed that bone marrow stromal cells could improve neurological deficits of various damages or diseases of the central nervous... | ['Animals', 'Bone Marrow Transplantation', 'Cell Differentiation', 'Cell Movement', 'Female', 'Immunohistochemistry', 'Models, Animal', 'Motor Activity', 'Multipotent Stem Cells', 'Nerve Regeneration', 'Rats', 'Rats, Sprague-Dawley', 'Recovery of Function', 'Stroke', 'Stromal Cells'] | 18,647,194 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Lowering of fasting and food stimulated serum immunoreactive gastric inhibitory polypeptide (GIP) by glucagon. | The effect of intravenous glucagon infusion on serum levels of immunoreactive GIP (IR-GIP), insulin (IRI), gastrin (IRG), and on blood glucose has been investigated in six healthy volunteers in the fasting state and during ingestion of a mixed standard meal. Glucagon (500 ng/kg/min) lowered significantly serum levels o... | ['Adult', 'Blood Glucose', 'Eating', 'Fasting', 'Female', 'Gastric Inhibitory Polypeptide', 'Gastrins', 'Gastrointestinal Hormones', 'Glucagon', 'Humans', 'Infusions, Parenteral', 'Insulin', 'Male'] | 856,672 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D06.472.317.400', 'D06.472.699.275', 'D12.644.400.300', 'D12.644.548.275', 'D12.776.631.650.300'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.54... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proteomics study of neuropathic and nonneuropathic dorsal root ganglia: altered protein regulation following segmental spinal nerve ligation injury. | Peripheral nerve injury is often followed by the development of severe neuropathic pain. Nerve degeneration accompanied by inflammatory mediators is thought to play a role in generation of neuropathic pain. Neuronal cell death follows axonal degeneration, devastating a vast number of molecules in injured neurons and th... | ['Analysis of Variance', 'Animals', 'Cell Death', 'Electrophoresis, Gel, Two-Dimensional', 'Ganglia, Spinal', 'Gene Expression Regulation', 'Ligation', 'Lumbar Vertebrae', 'Male', 'Mass Spectrometry', 'Neuralgia', 'Proteins', 'Proteomics', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Nerves'] | 17,213,366 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G04.146'], ['E05.196.401.250', 'E05.301.300.230'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.308'], ['E04.426'], ['A02.835.232.834.519'], ['E05.196.566'], ['C10.668.829.600', 'C23.888.592.612.664'], ['D12.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Extensive cell envelope modulation is associated with virulence in Brucella abortus. | Brucella virulence is linked to components of the cell envelope and tightly connected to the function of the BvrR/BvrS sensory-regulatory system. To quantify the impact of BvrR/BvrS on cell envelope proteins, we performed a label-free mass spectrometry-based proteomic analysis of spontaneously released outer membrane f... | ['Amino Acid Sequence', 'Bacterial Outer Membrane Proteins', 'Brucella abortus', 'Models, Biological', 'Molecular Sequence Data', 'Mutation', 'Periplasmic Proteins', 'Porins', 'Virulence'] | 17,343,405 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097.120', 'D12.776.543.100'], ['B03.440.400.425.215.500.100', 'B03.660.050.070.100.100'], ['E05.599.395'], ['L01.453.245.667'], ['G05.365.590'], ['D12.776.090.650', 'D12.776.097.577', 'D12.776.765.537'], ['D12.776.157.530.400.500', 'D12.776.543.550.450.730', 'D12.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The membrane spanning domains of protein NS4B from hepatitis C virus. | Determination of the membrane spanning domains of highly hydrophobic proteins from its primary structure, i.e., sequence, is cumbersome. However, transmembrane topology is better correlated with protein secondary structure than with the primary one. In this work we have determined the number and location of the transme... | ['Amino Acid Sequence', 'Cell Membrane', 'Hepacivirus', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'RNA, Viral', 'Viral Nonstructural Proteins'] | 22,884,469 | [['G02.111.570.060', 'L01.453.245.667.060'], ['A11.284.149'], ['B04.450.380', 'B04.820.578.344.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['G02.111.570.820.709.600'], ['G02.111.570.820.709.610'], ['D13.444.735.828'], ['D12.776.964.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Catalytic Conversion of Dinitrogen into Ammonia under Ambient Reaction Conditions by Using Proton Source from Water. | Molybdenum-catalyzed conversion of molecular dinitrogen into ammonia under ambient reaction conditions has been achieved by using a proton source generated in situ from the ruthenium-catalyzed oxidation of water in combination with visible light and a photosensitizer. The preset reaction system is considered as a new m... | ['Ammonia', 'Catalysis', 'Light', 'Molybdenum', 'Nitrogen', 'Organometallic Compounds', 'Oxidation-Reduction', 'Photosensitizing Agents', 'Protons', 'Ruthenium', 'Water'] | 28,815,926 | [['D01.362.075', 'D01.625.050'], ['G02.130'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['D01.268.604', 'D01.362.625'], ['D02.691'], ['G02.700', 'G03.295.531'], ['D27.505.954.444.600', 'D27.505.954.600.710'], ['D01.248.497.30... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Variability of clinical presentation in fumarate hydratase deficiency. | A 5-year-old girl with a previous diagnosis of cerebral palsy, nonprogressive psychomotor retardation, and hypotonia was found to excrete excessive fumaric acid in urine. Fumarate hydratase activity in skin fibroblasts was 10% of the control value. This case underscores the clinical heterogeneity of neurometabolic diso... | ['Cerebral Palsy', 'Child, Preschool', 'Diagnostic Errors', 'Female', 'Fumarate Hydratase', 'Fumarates', 'Humans', 'Intellectual Disability', 'Metabolism, Inborn Errors', 'Muscle Hypotonia', 'Succinates', 'Succinic Acid'] | 1,432,428 | [['C10.228.140.140.254'], ['M01.060.406.448'], ['E01.354', 'N02.421.450.280'], ['D08.811.520.241.300.300'], ['D02.241.081.337.302'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['C16.320.565', 'C18.452.648'], ['C10.597.613.575', 'C23.888.592... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of host desiccation on development, survival, and infectivity of entomopathogenic nematode Steinernema carpocapsae. | This study investigates the effect of host desiccation on entomopathogenic nematode (EPN) development, emergence, infectivity, and cross-protection against secondary environmental stress. Galleria mellonella hosts infected with the EPN Steinernema carpocapsae A10 were allowed to dehydrate in an environmental chamber fo... | ['Animals', 'Desiccation', 'Electrophoresis, Polyacrylamide Gel', 'Host-Parasite Interactions', 'Hydrogen-Ion Concentration', 'Moths', 'Pest Control, Biological', 'Proteins', 'Rhabditida', 'Rhabditida Infections', 'Temperature'] | 15,109,900 | [['B01.050'], ['E05.196.335', 'G02.176'], ['E05.196.401.402', 'E05.301.300.319'], ['G16.527.200.400'], ['G02.300'], ['B01.050.500.131.617.720.500.500.937.650'], ['N06.850.780.200.650.650'], ['D12.776'], ['B01.050.500.500.294.400.875'], ['C01.610.335.508.700.700'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of anisotonicity on pentose-phosphate pathway, oxidized glutathione release and t-butylhydroperoxide-induced oxidative stress in the perfused liver of air-breathing catfish, Clarias batrachus. | Both hypotonic exposure (185 mOsmol/l) and infusion of glutamine plus glycine (2 mmol/l each) along with the isotonic medium caused a significant increase of 14CO2 production from [1-14C]glucose by 110 and 70%, respectively, from the basal level of 18.4 +/- 1.2 nmol/g liver/min from the perfused liver of Clarias batrac... | ['Animals', 'Bile', 'Carbon Dioxide', 'Catfishes', 'Glucose', 'Glutamine', 'Glutathione', 'Glycine', 'Hepatocytes', 'L-Lactate Dehydrogenase', 'Liver', 'Osmotic Pressure', 'Oxidation-Reduction', 'Oxidative Stress', 'Pentose Phosphate Pathway', 'Perfusion', 'tert-Butylhydroperoxide'] | 15,286,415 | [['B01.050'], ['A12.200.087'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.493.080'], ['D09.947.875.359.448'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ['D12.644.456.448'], ['D12.125.481'], ['A11.436.348'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['A03.620'], [... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Study on the Mechanism of Low-Expressed Cancer Stem Cell Marker Lgr5 in Inhibition of the Proliferation and Invasion of Colorectal Carcinoma. | The present study intends to explore the influence of Lgr5 as a marker of tumor stem cells after siRNA interference on the proliferation and invasion of colorectal carcinoma (CRC) and its mechanism. The tissue samples were taken for biopsy from 32 cases of patients and 32 cases of normal subjects by colonoscopy. Real-t... | ['Aged', 'Biopsy', 'Cadherins', 'Carcinoma', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Colonoscopy', 'Colorectal Neoplasms', 'Female', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplastic Stem Cells', 'RNA Interference', 'RNA, Messenger', 'RNA, Small Interfering', 'Real-Time Polymerase... | 27,352,328 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Distance and temperature dependency in nonoverlapping and conventional F?rster resonance energy-transfer. | F?rster resonance energy-transfer (FRET) is a powerful and widely applied bioanalytical tool. According to the definition of FRET by F?rster, for energy-transfer to take place, a substantial spectral overlap between the donor emission and acceptor excitation spectra is required. Recently also a phenomenon termed nonove... | ['Fluorescence Resonance Energy Transfer', 'Fluorescent Dyes', 'Lanthanoid Series Elements', 'Nucleic Acid Hybridization', 'Oligonucleotides', 'Temperature'] | 22,007,728 | [['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D01.268.558.362', 'D01.552.550.399'], ['E05.393.661', 'G02.111.611'], ['D13.695.578.424'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Schistosomicidal and molluscicidal activities of aminoalkylamino substituted neo- and norneocryptolepine derivatives. | CONTEXT: The cryptolepines originate from the roots of the climbing shrub Cryptolepis sanguinolenta (Lindi) Schitr(Periplocaeae) which is used in Central and West Africa in traditional medicine for the treatment of malaria.OBJECTIVES: Evaluation for the first time of a series of chloro- and aminoalkylamino derivatives ... | ['Alkaloids', 'Animals', 'Biomphalaria', 'Cryptolepis', 'Egypt', 'Inhibitory Concentration 50', 'Lethal Dose 50', 'Medicine, African Traditional', 'Molluscacides', 'Puerto Rico', 'Quinolines', 'Schistosoma mansoni', 'Schistosomicides', 'Structure-Activity Relationship', 'Time Factors'] | 22,338,119 | [['D03.132'], ['B01.050'], ['B01.050.500.644.400.750.185'], ['B01.650.940.800.575.912.250.456.500.303'], ['Z01.058.266.317'], ['E05.940.350', 'G07.690.936.563'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['E02.190.488.505', 'E02.190.901.433', 'I01.076.201.450.654.505'], ['D27.720.031... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Neodymium:YAG laser ablation of posterior urethral valves. | We report successful neodymium:YAG laser ablation of posterior urethral valves in 6 boys. No strictures or incontinence resulted. | ['Cystostomy', 'Follow-Up Studies', 'Humans', 'Infant', 'Laser Therapy', 'Male', 'Reoperation', 'Urethra'] | 3,656,579 | [['E04.579.240', 'E04.950.774.852.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.594', 'E04.014.520'], ['E04.690'], ['A05.360.444.492.726', 'A05.810.876']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues. | BACKGROUND & AIMS: Celiac disease is a gluten-induced enteropathy that shows a strong association with HLA-DQ2 and -DQ8. Gluten-specific T cells, invariably restricted by DQ2 or DQ8, can be isolated from celiac lesions. Such gut-derived T cells have a preference for recognition of gluten that has been specifically deam... | ['Amino Acid Sequence', 'Celiac Disease', 'Epitopes', 'Gliadin', 'HLA-DQ Antigens', 'Humans', 'Molecular Sequence Data', 'Proline', 'Recombinant Proteins', 'T-Lymphocytes'] | 12,198,706 | [['G02.111.570.060', 'L01.453.245.667.060'], ['C06.405.469.637.250', 'C18.452.603.250'], ['D23.050.550'], ['D12.776.765.433.500.500.400', 'D12.776.765.725.500.500.400'], ['D12.776.395.550.509.400.430', 'D12.776.543.550.440.400.430', 'D23.050.301.500.400.400.430', 'D23.050.301.500.450.400.430', 'D23.050.705.552.410.400.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Birth of an illness, exemplified by Meni?re disease]. | Martin Luther's history and a case report by Grapengiesser in 1801 demonstrate that there were typical clinical manifestations of Meni?re's disease long before Meni?re's description. Luther suspected Satanic inflictions as cause of his disease; later on clinical pictures of this kind were interpreted as cerebral apople... | ['Europe', 'Famous Persons', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Male', 'Meniere Disease', 'Religion and Medicine'] | 8,439,349 | [['Z01.542'], ['K01.517.211.506', 'M01.228'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.568.217.500'], ['K01.844.619']] | ['Geographicals [Z]', 'Humanities [K]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Evolution of surface-based deformable image registration for adaptive radiotherapy of non-small cell lung cancer (NSCLC). | BACKGROUND: To evaluate the performance of surface-based deformable image registration (DR) for adaptive radiotherapy of non-small cell lung cancer (NSCLC).METHODS: Based on 13 patients with locally advanced NSCLC, CT images acquired at treatment planning, midway and the end of the radio- (n = 1) or radiochemotherapy (... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Carcinoma, Non-Small-Cell Lung', 'Humans', 'Imaging, Three-Dimensional', 'Lung Neoplasms', 'Middle Aged', 'Neoplasm Staging', 'Radiographic Image Interpretation, Computer-Assisted', 'Radiotherapy Planning, Computer-Assisted', 'Tomography, X-Ray Computed'] | 20,025,753 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Inbreeding in Finland. | We have compiled data on the frequency of first-cousin marriages in Finland using royal dispensation records for the time period 1810-1872 and national population statistics for the time period 1878-1920. For the earlier period, 0.315% of Finland's marriages were contracted between first cousins (2,331 of 739,387). Dur... | ['Consanguinity', 'Female', 'Finland', 'Humans', 'Language', 'Male', 'Marriage', 'Population Density', 'Regression Analysis', 'Rural Population', 'Socioeconomic Factors', 'Sweden', 'Urban Population'] | 2,021,189 | [['G05.090.403.180', 'G05.180'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308.500.500'], ['N01.224.600', 'N06.850.505.400.600'], ['E05.318.740.75... | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Three-dimensional structure of luminal plasma membrane protein from urinary bladder. | The structure of the membrane protein from urothelial plasma membrane has been investigated. A three-dimensional map has been obtained at 35 A resolution from negatively stained two-dimensional arrays of membrane proteins. The lattice space group has the symmetry p6. Twelve stain-excluding areas are resolvable on proje... | ['Animals', 'Crystallography', 'Fourier Analysis', 'Membrane Proteins', 'Microscopy, Electron', 'Models, Molecular', 'Protein Conformation', 'Swine', 'Urinary Bladder'] | 6,854,632 | [['B01.050'], ['E05.196.309', 'H01.181.529.240'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['D12.776.543'], ['E01.370.350.515.402', 'E05.595.402'], ['E05.599.595'], ['G02.111.570.820.709'], ['B01.050.150.900.649.313.500.880'], ['A05.810.890']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Occupation-related differences in the prevalence of metabolic syndrome. | OBJECTIVE: To investigate the prevalence of metabolic syndrome in the Spanish working population and determine how the prevalence varies according to occupation and sex.RESEARCH DESIGN AND METHODS: This was a cross-sectional study of 259,014 workers (mean age 36.4 years, range [16-74]; 72.9% male) who underwent a routi... | ['Blood Glucose', 'Body Size', 'Body Weight', 'Educational Status', 'Female', 'Humans', 'Income', 'Male', 'Metabolic Syndrome', 'Occupations', 'Prevalence', 'Sex Characteristics', 'Spain'] | 18,753,667 | [['D09.947.875.359.448.500'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['C1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Enantioselective synthesis of (R)-phenylephrine by Serratia marcescens BCRC10948 cells that homologously express SM_SDR. | A short-chain dehydrogenase/reductase from Serratia marcescens BCRC10948, SM_SDR, has been cloned and expressed in Escherichia coli for the bioconversion of 1-(3-hydroxyphenyl)-2-(methylamino) ethanone (HPMAE) to (R)-phenylephrine[(R)-PE]. However, only 5.11mM (R)-PE was obtained from 10mM HPMAE after a 9h conversion i... | ['Biocatalysis', 'Cloning, Molecular', 'Gene Expression Regulation, Bacterial', 'Phenylephrine', 'Serratia marcescens', 'Short Chain Dehydrogenase-Reductases', 'Stereoisomerism', 'Substrate Specificity'] | 29,310,851 | [['G02.111.086', 'G02.130.500', 'G03.105'], ['E05.393.220'], ['G05.308.300'], ['D02.033.100.291.617', 'D02.092.063.291.617'], ['B03.440.450.425.814.664', 'B03.660.250.150.720.500'], ['D08.811.682.047.820.900'], ['G02.607.445.682'], ['G02.111.835']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CTCF Regulates Otic Neurogenesis via Histone Modification in the Neurog1 | The inner ear is a complex sensory organ responsible for hearing and balance. Formation of the inner ear is dependent on tight regulation of spatial and temporal expression of genes that direct a series of developmental processes. Recently, epigenetic regulation has emerged as a crucial regulator of the development of ... | ['Acetylation', 'Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'CCCTC-Binding Factor', 'Cell Differentiation', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Ear, Inner', 'Embryo, Mammalian', 'Gene Deletion', 'Gene Expression Regulation, Developmental', 'Gene Knockdown Techniques', 'Genetic Loc... | 30,008,200 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['D12.776.157.687.157', 'D12.776.260.120', 'D12.776.660.235.050', 'D12.776.660.720.157', 'D12.776.664.235.050', 'D12.776.930.780.563'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exogenous regulators in the mycelium of Pleurotus ostreatus after exogenous application. | The mycelium of the fungus Pleurotus ostreatus was cultured on a synthetic medium with growth regulators. Best growth was observed on media with 100 ppm IAA, 200 ppm GA3 and 200 ppm of kinetin. Growth of terminal hyphae and the appearance of colonies differed characteristically. Auxin bio-assays showed that the content... | ['Agaricales', 'Cytokinins', 'Gibberellins', 'Indoleacetic Acids', 'Kinetin', 'Plant Growth Regulators'] | 564,319 | [['B01.300.179.100'], ['D03.633.100.759.138.525'], ['D02.455.849.291.239.500'], ['D03.066.288', 'D03.633.100.473.404'], ['D03.633.100.759.138.525.400'], ['D27.505.696.377.760']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of conserved peptides containing B-cell epitopes of Babesia bovis AMA-1 and their potential as diagnostics candidates. | The apical membrane antigen 1 (AMA-1) is a protein of the micronemes that is present in all organisms of the phylum Apicomplexa; it has been shown that AMA-1 plays an essential role for parasite invasion to target cells. It has been reported that AMA-1 is conserved among different isolates of Babesia; however, it is un... | ['Animals', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Babesia bovis', 'Babesiosis', 'Cattle', 'Cattle Diseases', 'Computer Simulation', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes, B-Lymphocyte', 'Fluorescent Antibody Technique, Indirect', 'Immunity, Humoral', 'Immunization', 'Membrane Proteins', 'Mexico', 'P... | 31,231,975 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['B01.043.075.600.580.070.100'], ['C01.610.701.688.122', 'C01.610.752.075', 'C01.610.752.625.122', 'C01.920.930.182', 'C22.674.710.122'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Patients' perceptions of the benefits and problems of using the ActiGait implanted drop-foot stimulator. | OBJECTIVE: To evaluate patients' perceptions of the benefits and problems associated with using the ActiGait implanted drop-foot stimulator.METHOD: Thirteen participants who had suffered a stroke at least 6 months prior to recruitment, had a drop-foot that affected walking and had taken part in a trial in which an Acti... | ['Electric Stimulation Therapy', 'Electrodes, Implanted', 'Gait Disorders, Neurologic', 'Humans', 'Patient Satisfaction', 'Quality of Life', 'Stroke', 'Stroke Rehabilitation', 'Surveys and Questionnaires', 'Walking'] | 19,242,627 | [['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['I01.800', 'K01.752.400.750', 'N06.850.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Back pain in in-vitro fertilized and spontaneous pregnancies. | The influence of ovarian stimulation in in-vitro fertilization (IVF) on the prevalence of back pain with onset during pregnancy was studied in 31 women who became pregnant after IVF treatment and compared with that of 200 spontaneously pregnant women. A two times higher prevalence rate of sacral pain in late pregnancy ... | ['Adolescent', 'Adult', 'Back Pain', 'Female', 'Fertilization in Vitro', 'Humans', 'Multivariate Analysis', 'Ovulation Induction', 'Pelvic Pain', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy, Multiple', 'Relaxin'] | 9,853,886 | [['M01.060.057'], ['M01.060.116'], ['C23.888.592.612.107'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E02.875.800.984', 'E05.820.800.984'], ['C23.888.592.612.944'], ['G08.686.784.769'], ['C13.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antagonism of Myc functions by Arf. | The Arf-Mdm2-p53 tumor suppressor pathway is activated by sustained hyperproliferative signals emanating from oncoproteins such as Myc. A recent study reveals a novel level of feedback control, whereby induced p19(Arf) binds to Myc and blocks cell proliferation by selectively impairing its transactivation functions. | ['Animals', 'Cell Division', 'Humans', 'Nuclear Proteins', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-mdm2', 'Proto-Oncogene Proteins c-myc', 'Signal Transduction', 'Tumor Suppressor Protein p14ARF', 'Tumor Suppressor Protein p53'] | 15,488,753 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['D12.776.624.664.700'], ['D08.811.464.938.750.562', 'D12.776.624.664.700.185', 'D12.776.660.764'], ['D12.776.260.103.813', 'D12.776.624.664.700.189', 'D12.776.660.76... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sharing of sensory terminals between the dynamic bag1 and static bag2 fibers in the rat muscle spindle. | The nuclear bag1 intrafusal fiber mediates the dynamic (velocity) sensitivity, whereas the nuclear bag2 and nuclear chain fibers mediate the static (length) sensitivity of muscle spindles to stretch. The pattern of branching of primary and secondary afferents, the distribution of their terminals to the 3 types of intra... | ['Animals', 'Axons', 'Female', 'Muscle Spindles', 'Nerve Fibers', 'Neurons, Afferent', 'Rats', 'Rats, Inbred Strains'] | 2,962,697 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.675.650.915.750.500', 'A08.800.950.750.500', 'A10.690.552.500.750', 'A11.671.650.915.750.500'], ['A08.675.542', 'A11.671.501'], ['A08.675.650', 'A11.671.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520... | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnostic utility of the Addenbrooke's Cognitive Examination - III (ACE-III), Mini-ACE, Mini-Mental State Examination, Montreal Cognitive Assessment, and Hasegawa Dementia Scale-Revised for detecting mild cognitive impairment and dementia. | BACKGROUND: Early detection of mild cognitive impairment (MCI) and dementia is important to promptly start appropriate intervention. However, it is difficult to examine a patient using long and thorough cognitive tests in a general clinical setting. In this study, we aimed to investigate the diagnostic validity of the ... | ['Aged', 'Aged, 80 and over', 'Cognition', 'Cognitive Dysfunction', 'Dementia', 'Female', 'Humans', 'Japan', 'Male', 'Mass Screening', 'Mental Status and Dementia Tests', 'Middle Aged', 'Neurologic Examination', 'ROC Curve', 'Reproducibility of Results'] | 31,448,862 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F02.463.188'], ['F03.615.250.700'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Klebsiella osteomyelitis of the right humerus involving the right shoulder joint in an infant. | Osteomyelitis in newborn infants is a rare infection. Lower extremity joints are commonly affected. Most of the cases have a haematogenous spread. Aerobes are the common group of organism involved, of which Staphylococcus aureus is the commonest. Klebsiella osteomyelitis has been reported as a cause of Osteomyelitis. H... | ['Anti-Bacterial Agents', 'Follow-Up Studies', 'Humans', 'Infant, Newborn', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Male', 'Meropenem', 'Osteomyelitis', 'Radiography', 'Sepsis', 'Shoulder Joint', 'Thienamycins', 'Treatment Outcome'] | 21,381,589 | [['D27.505.954.122.085'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C01.150.252.400.310.503'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['D02.065.589.099.124.300.750', 'D03.633.100.300... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of electrical stimulation of the striatum on bladder activity in cats. | AIMS: Parkinson's disease (PD) affects the nigrostriatal projections leading to micturition disturbance in most cases. Overactive bladder (OAB) symptoms such as urinary urgency or urgent urinary incontinence are common amongst PD patients. Several urodynamic studies have revealed that detrusor overactivity causes OAB s... | ['Animals', 'Cats', 'Caudate Nucleus', 'Electric Stimulation', 'Evoked Potentials', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Nerve Fibers', 'Neural Inhibition', 'Neural Pathways', 'Pressure', 'Putamen', 'Urinary Bladder', 'Urination'] | 19,214,990 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.249.487.550.184'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['A08.675.542', 'A11.671.501'], ['G07.265.755', 'G11.561.616'], ['A08.612'], ['G01.374.715'], ['A08.186.21... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Astigmatic changes in orthokeratology. | PURPOSE: To investigate and compare changes in refractive astigmatism and corneal toricity in orthokeratology (ortho-k) using the Thibos vector analysis.METHODS: Consecutive records of 74 patients (aged 7 to 16 years) who were fitted with spherical ortho-k lenses at the Optometry Clinic of The Hong Kong Polytechnic Uni... | ['Adolescent', 'Astigmatism', 'Child', 'Cornea', 'Corneal Topography', 'Humans', 'Orthokeratologic Procedures'] | 19,844,190 | [['M01.060.057'], ['C11.744.212'], ['M01.060.406'], ['A09.371.060.217'], ['E01.370.380.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.706']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The incidence of transient neurological symptoms after spinal anaesthesia with lidocaine compared to prilocaine. | The purpose of this double-blind study was to investigate the incidence of transient neurological symptoms after the use of isobaric lidocaine and isobaric prilocaine for spinal anaesthesia. Seventy patients (ASA 1-2, age between 18 and 70 years) were randomly assigned to two groups of 35 patients each, to receive eith... | ['Adolescent', 'Adult', 'Aged', 'Anesthesia, Spinal', 'Anesthetics, Local', 'Double-Blind Method', 'Female', 'Humans', 'Lidocaine', 'Male', 'Middle Aged', 'Pain', 'Paresthesia', 'Peripheral Nervous System Diseases', 'Prilocaine'] | 11,012,500 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E03.155.086.331'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.199.092.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of fructose 2,6-bisphosphate in mammary gland of fed, starved and re-fed lactating rats. | The fructose 2,6-bisphosphate (Fru-2,6-P2) content and intracellular concentration of lactating mammary gland was measured in fed, starved and re-fed rats. There was little or no change on starvation, and about 1.5-fold rise on re-feeding, contrasting with estimated glycolytic changes of about 10-fold. The 6-phosphofru... | ['Animals', 'Female', 'Food', 'Fructosediphosphates', 'Hexosediphosphates', 'Lactation', 'Mammary Glands, Animal', 'Phosphofructokinase-1', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'Starvation'] | 2,936,337 | [['B01.050'], ['G07.203.300', 'J02.500'], ['D09.894.417.313.300', 'D09.894.417.592.300'], ['D09.894.417.592'], ['G08.686.523', 'G08.686.702.500'], ['A10.336.482', 'A13.589'], ['D08.811.913.696.620.225.850.500'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Favourable long-term functional and radiographical outcome after osteoautograft transplantation surgery of the knee: a minimum 10-year follow-up. | PURPOSE: The aim of this study was to assess the progression of radiological cartilage changes and to document the functional, long-term results during a follow-up of 10 years after osteoautograft transplantation (OAT) knee surgery.METHODS: The study was a retrospective analysis of all patients who underwent OAT at Tur... | ['Adolescent', 'Adult', 'Autografts', 'Cartilage', 'Cartilage, Articular', 'Disease Progression', 'Female', 'Femur', 'Follow-Up Studies', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Osteochondritis Dissecans', 'Retrospective Studies', 'Young Adult'] | 29,860,602 | [['M01.060.057'], ['M01.060.116'], ['A01.941.750'], ['A02.165', 'A10.165.382'], ['A02.165.407.150', 'A02.835.583.192'], ['C23.550.291.656'], ['A02.835.232.043.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In-frame deletion of Escherichia coli essential genes in complex regulon. | A conditional knockout-rescue system was developed to construct an in-frame deletion strain ofEscherichia coli essential genes. The target was flanked with marker genes and FRT (FLP recognition target) sites, and a plasmid containing arabinose-induced FLP recombinase was transformed. After arabinose induction, cells co... | ['Escherichia coli', 'Gene Deletion', 'Genes, Bacterial', 'Genes, Essential', 'Genetic Complementation Test', 'Operon', 'Regulon'] | 18,330,348 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.270'], ['E05.393.281.526'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G05.360.340.024.742']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain acetaminophen measurement by in vivo dialysis, in vivo electrochemistry and tissue assay: a study of the dialysis technique in the rat. | After peripheral injections of the electrochemically active drug acetaminophen, striatal levels of the drug were measured in 3 different ways: in vivo electrochemistry, in vivo dialysis, and tissue assay. The time course of the acetaminophen concentrations measured by in vivo dialysis paralleled the in vivo electrochem... | ['Acetaminophen', 'Animals', 'Brain', 'Dialysis', 'Electrochemistry', 'Male', 'Neurochemistry', 'Osmolar Concentration', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 3,405,012 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['B01.050'], ['A08.186.211'], ['E05.196.353', 'G02.186'], ['H01.181.529.307'], ['H01.158.201.687', 'H01.158.610.110', 'H01.181.122.709'], ['G02.640'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.40... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Miniplaques and shapeless cerebral amyloid deposits in a case of Gerstmann-Str?ussler-Scheinker's syndrome. | Multicentric plaques of typical pathomorphology have been described in two members of the well-documented German family "Sch" with Gerstmann-Str?ussler-Scheinker's syndrome (GSS). The case of a third affected member with a clinical course of 10 years is now reported. In addition to multicentric plaques, small granules ... | ['Amyloid', 'Brain', 'Cerebellar Cortex', 'Female', 'Frontal Lobe', 'Gerstmann-Straussler-Scheinker Disease', 'Hippocampus', 'Humans', 'Middle Aged', 'Pedigree', 'Prions'] | 8,310,806 | [['D05.500.049', 'D12.776.049'], ['A08.186.211'], ['A08.186.211.132.810.428.200.212'], ['A08.186.211.200.885.287.500.270'], ['C01.207.800.350', 'C10.228.228.800.350', 'C10.574.500.425', 'C10.574.843.400', 'C16.320.400.350'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of the cardiorespiratory system of common carp (Cyprinus carpio) during severe hypoxia at three seasonal acclimation temperatures. | Little is known of the cardiorespiratory control mechanisms utilized by hypoxia-tolerant teleost fish to tolerate prolonged periods (h) of near anoxic exposure. Here, we report on the cardiorespiratory control mechanisms of the common carp Cyprinus carpio L. during normoxia and prolonged, severe hypoxic (<0.3 mg O(2) L... | ['Acclimatization', 'Adrenergic alpha-Antagonists', 'Adrenergic beta-Antagonists', 'Aminophylline', 'Animals', 'Atropine', 'Blood Pressure', 'Cardiac Output', 'Cardiotonic Agents', 'Cardiovascular Physiological Phenomena', 'Carps', 'Heart Rate', 'Hypoxia', 'Phentolamine', 'Propranolol', 'Respiration', 'Temperature'] | 16,691,527 | [['G07.025.133', 'G16.012.500.133'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D02.092.782.258.368.050', 'D03.633.100.759.758.824.751.075', 'D26.310.048'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Habitual nutrient intake in HIV-infected youth and associations with HIV-related factors. | Few studies have evaluated habitual nutrient intake among HIV-infected youth in the United States, even though diet may influence disease progression and risk of comorbidities. This study determined habitual micronutrient and macronutrient intake in HIV-infected youth. HIV-infected subjects and healthy controls 1-25 ye... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Disease Progression', 'Feeding Behavior', 'HIV Infections', 'Humans', 'Infant', 'United States', 'Young Adult'] | 24,953,143 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.656'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Cyclophosphamide therapy for rheumatoid arthritis. | Cyclophosphamide in high doses was given for six months to 19 patients with rheumatoid arthritis. A second group of patients with rheumatoid arthritis whose conditions were stable on low-dose prednisone received in addition either cyclophosphamide or placebo for six months. Measurements of joint function and joint infl... | ['Administration, Oral', 'Alopecia', 'Arthritis, Rheumatoid', 'Blood Sedimentation', 'Clinical Trials as Topic', 'Cyclophosphamide', 'Digestive System', 'Drug Therapy, Combination', 'Female', 'Humans', 'Leukocyte Count', 'Locomotion', 'Male', 'Physical Exertion', 'Placebos', 'Prednisone'] | 1,093,503 | [['E02.319.267.100'], ['C17.800.329.937.122', 'C23.300.035'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E01.370.225.625.125', 'E05.200.625.125'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['A03'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fuzzy logic algorithm for quantitative tissue characterization of diffuse liver diseases from ultrasound images. | Computerized ultrasound tissue characterization has become an objective means for diagnosis of liver diseases. It is difficult to differentiate diffuse liver diseases, namely cirrhotic and fatty liver by visual inspection from the ultrasound images. The visual criteria for differentiating diffused diseases are rather c... | ['Algorithms', 'Fuzzy Logic', 'Humans', 'Liver Diseases', 'Ultrasonography'] | 10,530,829 | [['G17.035', 'L01.224.050'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['E01.370.350.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus. | Systemic lupus erythematosus (SLE) patients have increased levels of interferon-alfa (IFN-alpha) in the circulation but a reduced number of functionally intact natural IFN-alpha producing cells (IPC) in peripheral blood. In search for tissue localisation of activated IPC, we investigated skin biopsies from SLE patients... | ['Adult', 'Aged', 'Aged, 80 and over', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Interferon-alpha', 'Lupus Erythematosus, Systemic', 'Middle Aged', 'RNA, Messenger', 'Skin'] | 11,480,846 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.5... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effects of mechanical ventilation with different tidal volumes on coagulation/fibrinolysis in rabbits with acute respiratory distress syndrome]. | OBJECTIVE: To observe the effects of mechanical ventilation with different tidal volumes (VT) on coagulability and fibrinolytic characteristics in rabbits with acute respiratory distress syndrome (ARDS) induced by two-hits with oleic acid (OA) and lipopolysaccharide (LPS).METHODS: Forty healthy adult male rabbits were ... | ['Acute Lung Injury', 'Animals', 'Blood Coagulation', 'Blood Gas Analysis', 'Fibrinolysis', 'Lung', 'Male', 'Rabbits', 'Respiration, Artificial', 'Tidal Volume'] | 26,138,421 | [['C08.381.520.500'], ['B01.050'], ['G09.188.390.150'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['G09.188.390.150.390'], ['A04.411'], ['B01.050.150.900.649.313.968.700'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['E01.370.386.700.485.750.900.350.750', 'G09.772.850.970.500.70... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A monoclonal-based, two-site enzyme immunoassay of human insulin. | A procedure is described for the efficient production of insulin-specific monoclonal antibodies, which involves primary and secondary immunization of BALB/c mice in the hind footpads with bovine or porcine insulin and fusion of lymphocytes from popliteal lymph nodes with a P3x63 murine myeloma line. With this protocol,... | ['Alkaline Phosphatase', 'Animals', 'Antibodies, Monoclonal', 'Antibody Affinity', 'Binding, Competitive', 'Cross Reactions', 'Female', 'Humans', 'Hybridomas', 'Immunoenzyme Techniques', 'Insulin', 'Methods', 'Mice', 'Mice, Inbred BALB C', 'Microchemistry'] | 3,553,334 | [['D08.811.277.352.650.035'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.040', 'G12.122.125'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G12.122.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.353.485', 'A11.251.600.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Validation and optimisation of a touchscreen progressive ratio test of motivation in male rats. | RATIONALE: Across species, effort-related motivation can be assessed by testing behaviour under a progressive ratio (PR) schedule of reinforcement. However, to date, PR tasks for rodents have been available using traditional operant response systems only.OBJECTIVES: Touchscreen operant response systems allow the assess... | ['Animals', 'Choice Behavior', 'Conditioning, Operant', 'Dextroamphetamine', 'Dopamine Antagonists', 'Dopamine Uptake Inhibitors', 'Male', 'Motivation', 'Raclopride', 'Rats', 'Rats, Sprague-Dawley', 'Reinforcement Schedule', 'Reinforcement, Psychology', 'Reward'] | 30,008,032 | [['B01.050'], ['F02.463.785.373.346'], ['F02.463.425.179.509'], ['D02.092.471.683.152.110.200'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['D27.505.519.562.437.220', 'D27.505.519.625.150.800', 'D27.505.519.625.600.220', 'D27.505.696.577.150.800', 'D27.505.696.577.600.220'], ['F01.658', 'F01.752.543.500.7... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation. | Glycosomes are peroxisome-related organelles that compartmentalize the glycolytic enzymes in kinetoplastid parasites. These organelles are developmentally regulated in their number and composition, allowing metabolic adaptation to the parasite's needs in the blood of mammalian hosts or within their arthropod vector. A ... | ['Life Cycle Stages', 'Microbodies', 'Optical Imaging', 'Phosphoprotein Phosphatases', 'Protein Tyrosine Phosphatases', 'Protozoan Proteins', 'Signal Transduction', 'Trypanosoma brucei brucei'] | 31,289,175 | [['B05.500', 'G07.345.500.550.500'], ['A11.284.430.214.190.500.585', 'A11.284.430.214.190.875.190.190.755'], ['E01.370.350.589', 'E05.642'], ['D08.811.277.352.650.625'], ['D08.811.277.352.650.775'], ['D12.776.820'], ['G02.111.820', 'G04.835'], ['B01.268.475.868.887.080']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2. | Some transcription factors that specifically bind double-stranded DNA appear to also function as RNA-binding proteins. Here, we demonstrate that the transcription factor Sox2 is able to directly bind RNA in vitro as well as in mouse and human cells. Sox2 targets RNA via a 60-amino-acid RNA binding motif (RBM) positione... | ['Amino Acid Motifs', 'Animals', 'Cells, Cultured', 'Cellular Reprogramming', 'DNA', 'Humans', 'Induced Pluripotent Stem Cells', 'Mice', 'Protein Binding', 'Protein Domains', 'RNA', 'RNA Splicing', 'SOXB1 Transcription Factors'] | 32,016,422 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['B01.050'], ['A11.251'], ['G04.152.262', 'G05.135'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An asymmetrical model of the airways of the dog lung. | A resin cast of the bronchial tree of a dog was studied down to branches of 0.5-mm diameter. The branches were ordered, and the number of branches, mean diameter, and mean length of branches in each order were determined. The model was developed from these data with the property that delta, the difference in order betw... | ['Animals', 'Bronchi', 'Dogs', 'Lung', 'Models, Biological'] | 7,061,267 | [['B01.050'], ['A04.411.125'], ['B01.050.150.900.649.313.750.250.216.200'], ['A04.411'], ['E05.599.395']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diarrhoea associated with ceftriaxone and its implications in paediatric patients. | We prospectively studied 50 paediatric patients (3 months-12 years) who received 50 mg/kg ceftriaxone, i.v. over 20 min every 12 h for 3-14 days. Diarrhoea, as defined by four bowel movements/day for two consecutive days, occurred in 34% (17) of 50 patients. An additional two patients with diarrhoea were excluded due t... | ['Bacterial Infections', 'Ceftriaxone', 'Child', 'Child, Preschool', 'Diarrhea', 'Humans', 'Infant', 'Prospective Studies'] | 2,793,955 | [['C01.150.252'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['M01.060.406'], ['M01.060.406.448'], ['C23.888.821.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.45... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Experience in staging malignant tumors of the orofacial area]. | The paper reports the authors experience at the Regina Elena Institute for the Study and Treatment of Tumours in Rome during the period 1987-1989 concerning the setting up of a register for primary malignant tumours of the head and neck. This experience has allowed various parameters to be assessed from the initial dia... | ['Facial Neoplasms', 'Humans', 'Incidence', 'Italy', 'Lip Neoplasms', 'Maxillary Sinus Neoplasms', 'Mouth Neoplasms', 'Neoplasm Staging', 'Pharyngeal Neoplasms', 'Sex Factors'] | 1,803,226 | [['C04.588.443.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.542.489'], ['C04.588.443.591.550', 'C07.465.409.640', 'C07.465.530.550'], ['C04.588.443.665.650.693.575', 'C08.460.669.693.575', ... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Comparison of quick and owren prothrombin time with regard to the harmonisation of the International Normalised Ratio (INR) system. | Prothrombin time (PT) is tested mostly to monitor patients on oral anticoagulant treatment. The International Normalised Ratio (INR) was introduced to improve and harmonise PT results and therapeutic range globally for patient care and the scientific literature. We studied the Quick PT in 179 patients and the Owren PT ... | ['Administration, Oral', 'Anticoagulants', 'Calibration', 'Drug Evaluation', 'Humans', 'International Normalized Ratio', 'Prothrombin Time', 'Reagent Kits, Diagnostic', 'Reference Values', 'Sensitivity and Specificity', 'Statistics as Topic'] | 12,059,082 | [['E02.319.267.100'], ['D27.505.954.502.119'], ['E05.978.155'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.320', 'E05.200.625.115.320'], ['E01.370.225.625.115.610', 'E05.200.625.115.610', 'G09.188.680'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical analysis of the soft tissue integration of non-submerged (ITI) and submerged (3i) implants: a prospective-controlled cohort study. | AIM: The aim of this study was to compare the soft tissue integration of submerged and non-submerged implants by means of periodontal parameter assessments and analysis.MATERIAL AND METHODS: Thirty-one patients, who received 42 non-submerged implants (ITI) and 48 submerged implants (3i), participated in the study. Ther... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Dental Devices, Home Care', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Plaque Index', 'Dental Prosthesis Design', 'Dental Prosthesis Retention', 'Educational Status', 'Female', 'Functional Laterality', 'Gingiva', 'Humans', 'Keratins', 'Male', ... | 18,828,814 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E06.186.250', 'E06.761.726.292', 'E07.222.250'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Cyclosporin A and phenytoin modulate inflammatory responses. | Gingival overgrowth is a common side-effect of administration of the immunosuppressant cyclosporin A and the anti-epileptic drug phenytoin. While cyclosporin-induced gingival overgrowth is often accompanied by gingival inflammation, phenytoin-induced gingival overgrowth usually forms fibrotic lesions. To determine whet... | ['Animals', 'Anticonvulsants', 'CHO Cells', 'Cells, Cultured', 'Cricetinae', 'Cricetulus', 'Cyclosporine', 'Down-Regulation', 'Escherichia coli', 'Female', 'Fibroblasts', 'Gingiva', 'Gingival Overgrowth', 'Humans', 'Immunosuppressive Agents', 'Intercellular Adhesion Molecule-1', 'Interleukin-6', 'Interleukin-8', 'Lipid... | 19,897,783 | [['B01.050'], ['D27.505.954.427.080'], ['A11.251.210.200', 'A11.436.155'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B03.440.450.425.325.300', 'B03.660.25... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of the cytoskeleton in capacitative calcium entry in myenteric glia. | Capacitative calcium entry (CCE) is the process by which intracellular calcium is replenished from the external milieu upon depletion of intracellular stores. CCE is thought to participate in chemotaxis, proliferation and cell signalling. A physical interaction between intracellular stores and the plasma membrane is po... | ['Animals', 'Antineoplastic Agents', 'Calcium', 'Cells, Cultured', 'Cytochalasin D', 'Cytoskeleton', 'Enteric Nervous System', 'Guinea Pigs', 'Male', 'Microscopy, Fluorescence', 'Myenteric Plexus', 'Neuroglia', 'Nocodazole', 'Nucleic Acid Synthesis Inhibitors'] | 12,787,337 | [['B01.050'], ['D27.505.954.248'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['D03.633.100.473.231.450', 'D23.946.587.370.450'], ['A11.284.430.214.190.750'], ['A08.800.050.150'], ['B01.050.150.900.649.313.992.550'], ['E01.370.350.515.458', 'E05.595.458'], ['A08.800.050.050.500', 'A08.800.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells. | Anthrax lethal toxin (LeTx) shows potent mitogen-activated protein kinase pathway inhibition and apoptosis in melanoma cells that harbor the activating V600E B-RAF mutation. LeTx is composed of two proteins, protective antigen and lethal factor. Uptake of the toxin into cells is dependent on proteolytic activation of p... | ['Antigens, Bacterial', 'Antineoplastic Agents', 'Bacterial Toxins', 'Cell Line, Tumor', 'Gelatinases', 'Humans', 'Matrix Metalloproteinases', 'Melanoma', 'Mutation', 'Proto-Oncogene Proteins B-raf', 'Tumor Cells, Cultured'] | 18,483,309 | [['D23.050.161'], ['D27.505.954.248'], ['D23.946.123'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.277.656.300.480.252', 'D08.811.277.656.675.374.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.525', 'D08.811.277.656.675.374.525'], ['C04.557.465.625.650.510', 'C04.557.580.625.65... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chiari malformation in female monozygotic twins. | We describe the cases of female monozygotic twins who presented almost synchronously with symptomatic Chiari malformation type I. Both were successfully treated with foramen magnum decompression. We analyse these findings in the context of previously reported cases and discuss the genetic implications. | ['Adult', 'Arnold-Chiari Malformation', 'Decompression, Surgical', 'Diseases in Twins', 'Female', 'Foramen Magnum', 'Humans', 'Treatment Outcome', 'Twins, Monozygotic'] | 20,649,405 | [['M01.060.116'], ['C10.500.680.291', 'C16.131.666.680.291'], ['E04.188'], ['C23.550.291.750'], ['A02.835.232.781.572.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['M01.438.873.940']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transfer of parahydrogen-induced hyperpolarization to 19F. | Homogeneous hydrogenations of unsaturated substrates with parahydrogen yield strong NMR signal enhancements of the transferred 1H nuclei if the symmetry of H2 is broken in the resulting hydrogenated products. This chemically induced hyperpolarization known as Parahydrogen-induced polarization (PHIP) is also transferred... | ['Fluorine Radioisotopes', 'Hydrogen', 'Magnetic Resonance Spectroscopy', 'Phenylacetates', 'Styrene'] | 16,526,631 | [['D01.496.749.340'], ['D01.268.406', 'D01.362.340'], ['E05.196.867.519'], ['D02.241.223.601'], ['D02.455.426.559.389.150.750.800']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Olfactory receptors in aquatic and terrestrial vertebrates. | In species representing different levels of vertebrate evolution, olfactory receptor genes have been identified by molecular cloning techniques. Comparing the deduced amino-acid sequences revealed that the olfactory receptor gene family of Rana esculenta resembles that of Xenopus laevis, indicating that amphibians in g... | ['Animals', 'Blotting, Southern', 'Brain Chemistry', 'Dolphins', 'Evolution, Molecular', 'Gene Expression', 'Goldfish', 'Molecular Sequence Data', 'Multigene Family', 'Nerve Tissue Proteins', 'Olfactory Receptor Neurons', 'Phylogeny', 'Pseudogenes', 'Rana esculenta', 'Sequence Homology, Amino Acid', 'Smell', 'Species S... | 9,839,455 | [['B01.050'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['G02.111.150', 'G03.185'], ['B01.050.150.900.649.313.875.267'], ['G05.045.250', 'G16.075.250'], ['G05.297'], ['B01.050.150.900.493.200.244.248.480'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['D12.776.631'], ['A04.531.520.573.580', 'A04.760.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Preference for hip protectors among older adults at high risk for osteoporotic fractures. | OBJECTIVE: To determine older adults' treatment preferences for osteoporosis comparing bisphosphonates and hip protectors.METHODS: Subjects at high risk for an osteoporotic hip fracture completed a discrete choice questionnaire to determine preferences for hip protectors versus oral weekly bisphosphonates. Simulations,... | ['Administration, Oral', 'Aged', 'Aged, 80 and over', 'Diphosphonates', 'Female', 'Hip Fractures', 'Humans', 'Male', 'Osteoporosis', 'Patient Compliance', 'Patient Education as Topic', 'Patient Satisfaction', 'Protective Devices', 'Risk Factors', 'Surveys and Questionnaires'] | 17,014,021 | [['E02.319.267.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.705.429.500'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.198.579', 'C18.452.104.579'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['I0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Study of the Intrinsic Fluorescence of a Highly Branched Cationic Dendrimer, Poly(Ethyleneimine) (PEI). | Poly(ethyleneimine) (PEI) is a weakly basic, synthetic, polycationic polymer, due to the presence of primary, secondary, and tertiary amino groups. The amino groups are responsible for the variety of applications of PEI (e.g., transfection, bioimaging, solar cell, etc.). Our study presents some new and reproducible met... | ['Aziridines', 'Cations', 'Dendrimers', 'Fluorescence', 'Hydrogen-Ion Concentration', 'Molecular Weight', 'Polyethyleneimine', 'Polymers'] | 31,615,035 | [['D03.383.097.217'], ['D01.248.497.300'], ['D05.750.327', 'E02.319.300.380.200', 'J01.637.512.600.200'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G02.300'], ['G02.494'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D05.750.716.507.600', 'D25.720.716.507.600', 'J01.637.051.720.716.507.600'], ['D05.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Risk factors for incidental durotomy during lumbar surgery: a retrospective study by multivariate analysis. | OBJECTIVE: The purpose of the present study was to use a prospectively collected data to evaluate the rate of incidental durotomy (ID) during lumbar surgery and determine the associated risk factors by using univariate and multivariate analysis.METHODS: We retrospectively reviewed 2184 patients who underwent lumbar sur... | ['Adult', 'Aged', 'Aged, 80 and over', 'Dura Mater', 'Female', 'Humans', 'Intraoperative Complications', 'Lumbar Vertebrae', 'Lumbosacral Region', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Postoperative Complications', 'Retrospective Studies', 'Risk Factors'] | 25,600,349 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.566.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['A02.835.232.834.519'], ['A01.923.176.519'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C23.550.767'], ['E05.... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cannabinoid-induced upregulation of serotonin 2A receptors in the hypothalamic paraventricular nucleus and anxiety-like behaviors in rats. | Recent behavioral reports suggest that repeated exposure to cannabis and synthetic cannabinoid agonists is linked with mental disorders associated with dysfunction of serotonin 2A (5-HT2A) receptor neurotransmission such as anxiety and depression. Here, we studied the effect of a nonselective cannabinoid agonist, CP559... | ['Animals', 'Anxiety', 'Behavior, Animal', 'Cannabinoid Receptor Antagonists', 'Cannabinoids', 'Cyclohexanols', 'Male', 'Paraventricular Hypothalamic Nucleus', 'Rats', 'Rats, Sprague-Dawley', 'Receptor, Serotonin, 5-HT2A', 'Up-Regulation'] | 23,721,787 | [['B01.050'], ['F01.470.132'], ['F01.145.113'], ['D27.505.519.625.085.750', 'D27.505.696.399.472.188.750'], ['D02.455.849.090'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['A08.186.211.180.497.342.400', 'A08.186.211.200.317.357.342.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['B... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase. | Ultraviolet B (UVB) induces phosphorylation of histone H3 at serine 10, and mitogen-activated protein kinases are involved in this signal transduction pathway. Here we provide evidence that Fyn kinase, a member of the Src kinase family, is involved in the UVB-induced phosphorylation of histone H3 at serine 10. UVB dist... | ['Animals', 'Cell Line', 'Cell Line, Tumor', 'Dose-Response Relationship, Drug', 'Genes, Dominant', 'Histones', 'Humans', 'Isoxazoles', 'Leflunomide', 'MAP Kinase Signaling System', 'Mice', 'Models, Biological', 'Phosphorylation', 'Plasmids', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Proteins', 'Proto-Oncogen... | 15,537,652 | [['B01.050'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.360.340.024.340.240', 'G05.420.320'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.385'], ['D03.383.129.385.475'], ['G... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Value added: increasing the power to assess treatment outcome in joint haemorrhages. | Subject reports of efficacy of treatment of haemophilia-related joint bleeding are by definition subjective, yet are often the primary outcome in studies comparing therapies. Verbal descriptors such as effective, partially effective, poorly effective, not effective are treated as dichotomous or categorical variables in... | ['Adolescent', 'Adult', 'Blood Coagulation Factors', 'Child', 'Europe', 'Hemarthrosis', 'Hemophilia A', 'Humans', 'Middle Aged', 'Models, Statistical', 'Multicenter Studies as Topic', 'Pain Measurement', 'Randomized Controlled Trials as Topic', 'Treatment Outcome'] | 18,194,307 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.125', 'D23.119'], ['M01.060.406'], ['Z01.542'], ['C05.550.459', 'C23.550.414.794'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.83... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Granuloma Annulare-Like Granulomatous Reaction to Red Tattoo Pigment. | Cutaneous reactions to tattoos can be attributed either to trauma or to the exogenous pigment introduced into the skin. Red pigment is associated with a high sensitizing potential and is the most frequently implicated pigment inducing various types of histological reactions. Herein, we describe a patient with red tatto... | ['Adult', 'Coloring Agents', 'Dermatitis', 'Forearm', 'Granuloma Annulare', 'Humans', 'Male', 'Skin', 'Tattooing'] | 29,658,308 | [['M01.060.116'], ['D27.720.233'], ['C17.800.174'], ['A01.378.800.585'], ['C17.300.200.495.380', 'C17.800.550.380', 'C23.550.382.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A17.815'], ['E02.218.085.840', 'E04.085.840']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of vinblastine containing chemotherapy on tumor tissue membrane fluidity; an EPR study. A case report. | The influence of vinblastine (VLB) in combined chemotherapy on tumor cell membrane fluidity of a patient with exulcerated soft tissue sarcoma was studied by the electron paramagnetic resonance method (EPR). Tissue samples were taken before and after applications of VLB, Cis-Platinum (CDP) and combined intraarterial che... | ['Antineoplastic Combined Chemotherapy Protocols', 'Electron Spin Resonance Spectroscopy', 'Humans', 'Male', 'Membrane Fluidity', 'Middle Aged', 'Sarcoma', 'Soft Tissue Neoplasms', 'Spin Labels', 'Vinblastine'] | 2,835,939 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.196.867.519.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.154.500', 'G02.111.550', 'G04.570'], ['M01.060.116.630'], ['C04.557.450.795'], ['C04.588.839'], ['D02.389.678'], ['D03.132.436.681.827.650', 'D03.633.100.473.402.681.827.650', 'D03... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Microsomal formation of N-benzyl-4-hydroxymethylaniline from N-benzyl-4-methylaniline. | The in-vitro metabolism of N-benzyl-4-methylaniline was re-examined using male hamster and rabbit hepatic microsomes; both species generated N-benzyl-4-hydroxymethylaniline, confirmed by TLC and HPLC, comparison with authentic compound. Further confirmation of the formation of this metabolite was achieved by use of a r... | ['Animals', 'Benzylamines', 'Biotransformation', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Cricetinae', 'In Vitro Techniques', 'Male', 'Microsomes, Liver', 'Rabbits', 'Toluidines'] | 1,360,516 | [['B01.050'], ['D02.092.200', 'D02.455.426.559.389.140.210'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['B01.050.150.900.649.313.992.635.075.250'], ['E05.481'], ['A11.284.835.540.541'], ['B01.050.150.900.649.313.968.700'], ['D02.092.146.859', 'D02.455.426.559.389.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
One stage procedure in the management of acute sigmoid volvulus without colonic lavage. | BACKGROUND: There is a growing acceptance of one-stage primary resection and anastomosis of left-sided colon obstruction with on-table antegrade colonic lavage to reduce the risk of post-operative infectious complications and anastomotic dehiscence. The purpose of this study was to evaluate the safety of single-stage r... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anastomosis, Surgical', 'Colectomy', 'Decompression, Surgical', 'Female', 'Follow-Up Studies', 'Humans', 'Intestinal Volvulus', 'Male', 'Middle Aged', 'Prospective Studies', 'Rectum', 'Sigmoid Diseases', 'Treatment Outcome'] | 17,958,224 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.035'], ['E04.210.219'], ['E04.188'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531.568', 'C23.300.970.500'], ['M01.060.116.630'], ['E05.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Significance of multiple nodal basin drainage in truncal melanoma patients undergoing sentinel lymph node biopsy. | BACKGROUND: Although previous studies have demonstrated that truncal site is associated with an adverse prognosis, explanations for such risk are lacking. In addition, the number of nodal basins as well as the number of lymph nodes containing regional metastases are important prognostic factors in these patients. Becau... | ['Biopsy', 'Female', 'Humans', 'Intraoperative Period', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Melanoma', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'Radionuclide Imaging', 'Risk', 'Skin Neoplasms', 'Thorax'] | 10,819,364 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.650.560'], ['C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Case report of advanced renal cancer that showed different responses to the alteration of therapeutic cytokines]. | We report a case of advanced renal cancer that showed different responses to the alteration of therapeutic cytokines. A 73-year-old man presented with asymptomatic macrohematuria, and was diagnosed as right renal cancer (11 x 9 x 9 cm in diameter) with metastases to abdominal and mediastinal lymph nodes (cT3bN2M1, stag... | ['Aged', 'Antineoplastic Agents', 'Disease Progression', 'Embolization, Therapeutic', 'Humans', 'Interferon-alpha', 'Interleukin-2', 'Kidney Neoplasms', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Renal Artery', 'Treatment Outcome'] | 16,613,162 | [['M01.060.116.100'], ['D27.505.954.248'], ['C23.550.291.656'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.250'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Iatrogenic bowel obstruction caused by balloon-inflated feeding tubes. | OBJECTIVE: To determine whether balloon-inflated feeding tubes may be a cause of bowel obstruction.METHODS: Evaluation of 10 patients with balloon-inflated feeding tubes who experienced cramping, nausea and vomiting. Conventional radiography of the abdomen was performed in all patients, a fluoroscopic barium examinatio... | ['Aged', 'Aged, 80 and over', 'Catheterization', 'Enteral Nutrition', 'Equipment Failure', 'Female', 'Humans', 'Intestinal Obstruction', 'Intubation, Gastrointestinal', 'Male', 'Middle Aged', 'Radiography'] | 10,226,632 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148', 'E05.157'], ['E02.421.360', 'E02.642.500.360'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['E02.585.412', 'E05.497.412'], ['M01.060.116.630'], ['E01.370.350.700']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case report: Rastelli operation for double outlet right ventricle associated with a chordae insertion to the infundibular septum]. | A successful Rastelli operation for double outlet right ventricle (DORV) with a chordae insertion of the tricuspid valve to the infundibular septum was reported. A patient was a 6-year-old boy and the diagnosis was DORV, d-malposition of the aorta and pulmonary stenosis. The infundibular septum was not resected but mob... | ['Child', 'Chordae Tendineae', 'Double Outlet Right Ventricle', 'Heart Septal Defects, Atrial', 'Heart Septum', 'Humans', 'Male', 'Pulmonary Valve Stenosis', 'Tricuspid Valve'] | 1,619,825 | [['M01.060.406'], ['A07.541.510.240'], ['C14.240.400.560.540.500', 'C14.240.400.915.300', 'C14.280.400.560.540.500', 'C14.280.400.915.300', 'C16.131.240.400.560.540.500', 'C16.131.240.400.915.300'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560.375'], ['A07.541.459'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The diagnostic value of fine needle aspiration cytology in Waldeyer's ring lymphomas. | Fine needle aspiration cytology (FNAC) is a well-established diagnostic technique for tumours in the head and neck area. In recent years FNAC has been established as an accurate and useful method for the diagnosis of nodal malignant lymphoproliferative disease. The purpose of the present study was to determine and eval... | ['Adult', 'Aged', 'Biopsy, Needle', 'Female', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Sensitivity and Specificity', 'Tonsillar Neoplasms'] | 11,120,481 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption. | BACKGROUND: In the accompanying article, we showed that activation of peroxisome proliferator-activated receptor alpha (PPARá) signaling by fenofibrate and tesaglitazar decreases ethanol (EtOH) consumption in mice. In this study, we determined the role of these PPAR agonists in EtOH-related behaviors and other actions ... | ['Alcohol Drinking', 'Alkanesulfonates', 'Animals', 'Avoidance Learning', 'Conditioning, Classical', 'Female', 'Fenofibrate', 'Locomotion', 'Male', 'Mice', 'Mice, 129 Strain', 'Mice, Inbred C57BL', 'PPAR alpha', 'Phenylpropionates', 'Reflex, Righting', 'Taste'] | 26,857,541 | [['F01.145.317.269'], ['D02.455.326.146.100.050', 'D02.886.645.600.055.050'], ['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.425.179.308'], ['D02.241.081.114.968.500.625', 'D02.355.726.305.625', 'D02.455.426.559.389.134.750', 'D02.455.426.559.389.657.654.305.625', 'D02.522.223.750'], ['G07.568.500',... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"There are risks to be taken and some just push it too far": how farmers perceive quad-bike incident risk. | OBJECTIVE: To qualitatively explore how farmers perceive personal risk of an occupational quad-bike incident and develop a model of the factors that modify this perception.METHODS: Grounded theory methods were used to inform data collection and analysis. Semi-structured interviews were undertaken with eight New Zealand... | ['Accidents, Occupational', 'Adult', 'Agriculture', 'Attitude', 'Farmers', 'Female', 'Grounded Theory', 'Humans', 'Interviews as Topic', 'Knowledge', 'Male', 'Middle Aged', 'Off-Road Motor Vehicles', 'Perception', 'Qualitative Research', 'Risk Assessment', 'Risk-Taking', 'Surveys and Questionnaires'] | 26,456,529 | [['N06.850.135.240'], ['M01.060.116'], ['J01.040'], ['F01.100'], ['M01.526.390'], ['H01.770.644.241.424'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['K01.468'], ['M01.060.116.630'], ['J01.937.500.600'], ['F02.463.593'], ['H01.... | ['Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Complications of nonoperative management of pediatric blunt hepatic injury: Diagnosis, management, and outcomes. | BACKGROUND: Nonoperative management (NOM) of blunt hepatic injury is the standard of care in the hemodynamically stable pediatric patient, but it is not without pitfalls. The purpose of this study is to assess the incidence and types of complications associated with NOM in terms of diagnosis, management, and outcomes.M... | ['Adolescent', 'Biliary Tract Diseases', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Liver', 'Liver Diseases', 'Male', 'Retrospective Studies', 'Treatment Outcome', 'United States', 'Wounds, Nonpenetrating'] | 16,917,447 | [['M01.060.057'], ['C06.130'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A03.620'], ['C06.552'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.52... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions. | Multiphoton excitation microscopy (MPM) is regarded as an effective tool that enables the visualization of deep regions within living tissues and organs, with little damage. Here, we report novel non-labeling MPM (NL-MPM) imaging of fresh human colorectal mucosa, which is useful for discriminating cancer lesions from n... | ['Basement Membrane', 'Colorectal Neoplasms', 'Epithelial Cells', 'Flavin-Adenine Dinucleotide', 'Humans', 'Intestinal Mucosa', 'Microscopy, Fluorescence, Multiphoton', 'NAD', 'NADP', 'Radiographic Image Interpretation, Computer-Assisted', 'Sensitivity and Specificity'] | 28,761,050 | [['A10.272.220', 'A10.615.179'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['A11.436'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D13.695.667.138.... | ['Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Human Papillomavirus Vaccine as an Anticancer Vaccine: Collaborative Efforts to Promote Human Papillomavirus Vaccine in the National Comprehensive Cancer Control Program. | Widespread use of the human papillomavirus (HPV) vaccine has the potential to reduce incidence from HPV-associated cancers. However, vaccine uptake among adolescents remains well below the Healthy People 2020 targets. The Centers for Disease Control and Prevention (CDC) National Comprehensive Cancer Control Program (NC... | ['Adolescent', 'Centers for Disease Control and Prevention, U.S.', 'Female', 'Humans', 'Immunization Programs', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'United States', 'Uterine Cervical Neoplasms', 'Vaccination'] | 28,263,672 | [['M01.060.057'], ['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.608'], ['C01.925.256.650', 'C01.925.928.725'], ['D20.215.894.899.498'], ['Z01.107.567.875'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.762.85... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mastoid pneumatization in otosclerosis. | The extent of mastoid pneumatization in 150 otosclerotic ears was compared with that of 150 healthy control ears. The size of mastoid pneumatization was measured by use of the Sch?ller lateral x-ray projection with the help of computed planimetry. The measurements showed the average pneumatized area in otosclerotic ear... | ['Adult', 'Aged', 'Humans', 'Mastoid', 'Middle Aged', 'Otosclerosis', 'Radiography'] | 2,729,830 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.885.444'], ['M01.060.116.630'], ['C09.218.768'], ['E01.370.350.700']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Phylogenetic and disruption analyses of aspartate kinase of Deinococcus radiodurans. | The extremely radioresistant bacterium Deinococcus radiodurans is evolutionarily closely related to the extremely thermophilic bacterium Thermus thermophilus. These bacteria have a single gene encoding an aspartate kinase (AK) that catalyzes the phosphorylation of L-aspartate. T. thermophilus has an aminoadipate pathwa... | ['Aspartate Kinase', 'Biological Evolution', 'Culture Media', 'Deinococcus', 'Genome, Bacterial', 'Homoserine Dehydrogenase', 'Phylogeny', 'Prokaryotic Cells', 'Thermus thermophilus'] | 17,420,586 | [['D08.811.913.696.630.050'], ['G05.045', 'G16.075'], ['D27.720.470.305', 'E07.206'], ['B03.510.400.200'], ['G05.360.340.358.207'], ['D08.811.682.047.820.300'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['A11.760'], ['B03.440.400.425.875.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
ABC in Uganda: success or subterfuge? | Since the enactment of the US President's Emergency Plan for AIDS Relief (PEPFAR) in 2003, US officials have repeatedly pointed to Uganda as an example of the effectiveness of the "ABC" (Abstain, Be faithful, use Condoms) approach to HIV prevention. Uganda is one of few African countries to have experienced a decline i... | ['Condoms', 'HIV Infections', 'HIV Seroprevalence', 'Humans', 'Program Evaluation', 'Sexual Abstinence', 'Uganda'] | 16,365,967 | [['E07.190.270.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['E05.318.372.500.950.375', 'N05.715.360.330.500.950.375', 'N06.850.520.450.500.950.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.337.820', 'N04.761.685', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. | BACKGROUND: CDKN2A/p16INK4a is frequently altered in human cancers and it is the most important melanoma susceptibility gene identified to date. p16INK4a inhibits pRb phosphorylation and induces cell cycle arrest, which is considered its main tumour suppressor function. Nevertheless, additional activities may contribut... | ['Blotting, Western', 'Cell Cycle', 'Cell Line, Tumor', 'Cellular Senescence', 'Cyclin-Dependent Kinase Inhibitor p16', 'DNA Helicases', 'Humans', 'Immunohistochemistry', 'Immunoprecipitation', 'Melanoma', 'Nuclear Proteins', 'Protein Binding', 'Signal Transduction', 'Transcription Factors', 'Two-Hybrid System Techniqu... | 19,149,898 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.043'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['B01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Microbial degradation of trifluralin by Aspergillus carneus, Fusarium oxysporum and Trichoderma viride. | 3H-Trifluralin was synthesized by condensation of 3H-4-chloro-3,5-dinitro-alpha, alpha, alpha-trifluorotoluene with di-n-propylamine. After incubation of trifluralin with Aspergillus carneus, Fusarium oxysporum and Trichoderma viride for 10 days, a small percentage (less than 10%) of unchanged herbicide was recovered i... | ['Aspergillus', 'Biodegradation, Environmental', 'Fusarium', 'Isotope Labeling', 'Mitosporic Fungi', 'Toluidines', 'Trichoderma', 'Trifluralin'] | 6,682,873 | [['B01.300.381.081'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['B01.300.381.366'], ['E05.522'], ['B01.300.381'], ['D02.092.146.859', 'D02.455.426.559.389.832.559'], ['B01.300.381.910'], ['D02.092.146.859.717', 'D02.455.426.559.389.832.767']] | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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