Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lactate dehydrogenase isoenzyme composition of human platelets. | The LDH isoenzyme composition of 12 platelet preparations was determined by electrophoresis. The mean (+/- SD) percentages of LDH-1, LDH-2, LDH-3, LDH-4, and LDH-5 were 16.6 +/- 1.7, 30.1 +/- 1.0, 34.2 +/- 1.3, 18.2 +/- 1.3, and 0.9 +/- 1.1, respectively. In comparison with previous data, these data show identical rank... | ['Blood Platelets', 'Electrophoresis', 'Humans', 'Isoenzymes', 'L-Lactate Dehydrogenase', 'Temperature'] | 2,591,051 | [['A11.118.188', 'A15.145.229.188'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structure of the O-antigen of Yersinia pseudotuberculosis O:4a revised. | The O-specific polysaccharide was isolated by mild acid degradation of the lipopolysaccharide of Yersinia pseudotuberculosis O:4a and studied by NMR spectroscopy, including 2D ROESY and (1)H, (13)C HMBC experiments. The following structure of the pentasaccharide repeating unit of the polysaccharide was established, whi... | ['Carbohydrate Sequence', 'Hexoses', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'O Antigens', 'Yersinia pseudotuberculosis'] | 19,117,553 | [['G02.111.570.160', 'L01.453.245.667.160'], ['D09.947.875.359'], ['E05.196.867.519'], ['L01.453.245.667'], ['D09.698.718.450.600', 'D10.494.600', 'D23.050.161.616.525.600', 'D23.946.123.329.500.600'], ['B03.440.450.425.900.615', 'B03.660.250.150.950.590']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Management of malignant gastric outlet obstruction with a modified triple-layer covered metal stent. | BACKGROUND: A high incidence of migration with covered metal stents has been reported in malignant gastric outlet obstruction (GOO). A newly modified, partially covered, triple-layer nitinol stent was developed that has a longer uncovered portion (5-15 mm) to prevent stent migration.OBJECTIVE: To estimate the efficacy ... | ['Aged', 'Alloys', 'Bile Duct Neoplasms', 'Carcinoma', 'Cholangiocarcinoma', 'Female', 'Gastric Outlet Obstruction', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Prosthesis Failure', 'Stents', 'Stomach Neoplasms'] | 22,284,092 | [['M01.060.116.100'], ['D01.552.033', 'D25.058', 'J01.637.051.058'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['C04.557.470.200'], ['C04.557.470.200.025.450'], ['C06.405.748.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Aortic regurgitation developed seven years after mediastinal radiation therapy: report of a case]. | We report on radiation-induced valvular dysfunction in a 41-year-old woman who developed aortic regurgitation with clinical symptoms, requiring aortic valve replacement seven years after mediastinal radiation therapy for carcinoma of the breast. She was treated with cobalt radiation therapy of 4000 rads to her left med... | ['Adult', 'Aortic Valve Insufficiency', 'Breast Neoplasms', 'Female', 'Heart Valve Prosthesis', 'Humans', 'Mediastinum', 'Radiation Injuries', 'Radiotherapy', 'Time Factors'] | 8,336,440 | [['M01.060.116'], ['C14.280.484.048.500'], ['C04.588.180', 'C17.800.090.500'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.761.800.500'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E02.815'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Augmented uptake of neuraminidase-treated sheep red blood cells: participation of opsonic factors. | Neuraminidase from Vibrio cholerae (VCN) was used to treat sheep red blood cells (SRBC) which were then incubated in vitro with murine peritoneal macrophages. The uptake of VCN-treated SRBC by macrophages was greater than the uptake of SRBC not treated with VCN. SRBC opsonized with normal mouse serum (NMS) were taken u... | ['Animals', 'Epitopes', 'Erythrocytes', 'Female', 'Macrophages', 'Mice', 'Mice, Inbred C3H', 'Neuraminidase', 'Opsonin Proteins', 'Phagocytosis', 'Sheep', 'Vibrio cholerae'] | 48,553 | [['B01.050'], ['D23.050.550'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388'], ['D08.811.277.450.692'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fractional limb volume--a soft tissue parameter of fetal body composition: validation, technical considerations and normal ranges during pregnancy. | OBJECTIVES: The main goals were to provide normal reference ranges for fractional limb volume as a new index of generalized fetal nutritional status, to evaluate the reproducibility of fractional fetal limb volume measurements during the second and third trimesters of pregnancy, and to demonstrate technical considerati... | ['Adult', 'Anthropometry', 'Arm', 'Body Composition', 'Cross-Sectional Studies', 'Female', 'Fetal Development', 'Gestational Age', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Observer Variation', 'Pregnancy', 'Reference Values', 'Reproducibility of Results', 'Thigh', 'Ultrasonography, Prenatal'] | 19,253,340 | [['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['A01.378.800.075'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.345.500.325.235', 'G08.686.784.170.157'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Liver metastasis models of colon cancer for evaluation of drug efficacy using NOD/Shi-scid IL2Rgammanull (NOG) mice. | To examine the drug efficacy of a novel farnesyltransferase inhibitor (FTI), CH4512600, in vivo, we developed a reliable liver metastasis model of human colon cancer using NOD/Shi-scid IL2Rgamma(null) (NOG) mice. Eleven human colon cancer cell lines were examined for their ability to form diverse metastatic foci in the... | ['Animals', 'Antineoplastic Agents', 'Benzofurans', 'Cell Line, Tumor', 'Colonic Neoplasms', 'Farnesyltranstransferase', 'Humans', 'Imidazoles', 'Liver Neoplasms, Experimental', 'Mice', 'Mice, Inbred NOD', 'Mice, SCID', 'Neoplasm Transplantation', 'Receptors, Interleukin-2', 'Transplantation, Heterologous', 'Vascular E... | 18,097,554 | [['B01.050'], ['D27.505.954.248'], ['D03.633.100.127'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D08.811.913.225.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Substance Use Patterns of HIV-Infected Russian Women with and Without Hepatitis C Virus Co-infection. | Individuals with HIV and hepatitis C virus (HCV) co-infection may experience substance use related health complications. This study characterized substance use patterns between HIV/HCV co-infected and HIV mono-infected Russian women. HIV-infected women (N = 247; M age = 30.0) in St. Petersburg, Russia, completed a surv... | ['Adult', 'Coinfection', 'Female', 'HIV Infections', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Prevalence', 'Russia', 'Sexual Behavior', 'Substance Abuse, Intravenous', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Young Adult'] | 26,995,679 | [['M01.060.116'], ['C01.218'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Acylation-dependent protein export in Leishmania. | The surface of the protozoan parasite Leishmania is unusual in that it consists predominantly of glycosylphosphatidylinositol-anchored glycoconjugates and proteins. Additionally, a family of hydrophilic acylated surface proteins (HASPs) has been localized to the extracellular face of the plasma membrane in infective pa... | ['Acylation', 'Amino Acid Sequence', 'Animals', 'Biological Transport', 'Cell Membrane', 'Leishmania', 'Microscopy, Immunoelectron', 'Molecular Sequence Data', 'Protozoan Proteins', 'Structure-Activity Relationship'] | 10,753,904 | [['G02.111.012', 'G02.607.063', 'G03.040'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G03.143'], ['A11.284.149'], ['B01.268.475.868.488'], ['E01.370.350.515.402.625', 'E05.595.402.625'], ['L01.453.245.667'], ['D12.776.820'], ['G02.111.830', 'G07.690.773.997']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interaction of proteinase inhibitors with phospholipid vesicles is modulated by pH. | rBbKI and rBbCI, plant recombinant inhibitors from Bauhinia bauhinioides, and BpuTI from Bauhinia purpurea seeds distinctly and specifically block proteolytic enzymes. The secondary structures of those inhibitors were compared and their interactions with phospholipid vesicles were evaluated by the release of calcein an... | ['Animals', 'Cattle', 'Circular Dichroism', 'Fluoresceins', 'Humans', 'Hydrogen-Ion Concentration', 'Peptide Hydrolases', 'Phospholipids', 'Protease Inhibitors', 'Protein Structure, Secondary', 'Spectrometry, Fluorescence', 'Sus scrofa', 'Temperature', 'Unilamellar Liposomes'] | 20,692,285 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.867.151'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D08.811.277.656'], ['D10.570.755'], ['D27.505.519.389.745'], ['G02.111.570.820.709.600'], ['E05.196.712.516.600.676',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Finite element modeling of material property assignment based on CT gray value and its application in simulation of osteotomy for deformities]. | OBJECTIVE: To explore a new method for finite element modeling to achieve material property assignment based on in situ CT gray value in simulated osteotomies for deformities.METHODS: A CT scan dataset of the lower limb of a patient with extorsion deformity was obtained for three-dimensional reconstruction using Mimics... | ['Finite Element Analysis', 'Humans', 'Models, Anatomic', 'Osteotomy', 'Software', 'Tibia', 'Tomography, X-Ray Computed'] | 27,435,780 | [['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['E04.555.580'], ['L01.224.900'], ['A02.835.232.043.650.883'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[A complex study on the effects of workplace air pollution in acid-digestion plants manufacturing sulphite cellulose on the health status of workers]. | The study was designed to analyze working conditions in acid digestion shops of integrated pulp-and-paper mills employing sulphite technique of cellulose manufacture. It was established that workplace air pollution by sulphur epoxide appeared to be a major occupational hazard. MACs being exceeded, the workers experienc... | ['Air Pollutants, Occupational', 'Cellulose', 'Female', 'Humans', 'Male', 'Middle Aged', 'Occupational Diseases', 'Sulfites'] | 2,767,481 | [['D27.888.284.101.268'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C24'], ['D01.248.497.158.904', 'D01.875.750']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Dynamics of portal and peripheral endothelin-1 in hepatic resection and its implication. | BACKGROUND: The liver and portal circulation contribute to production and clearance of endothelin-1 (ET-1). This study was undertaken to investigate what variables relate to the dynamics of ET-1 in hepatic resection and its clinical implication.PATIENTS AND METHODS: On 20 patients with (n = 8) or without (n = 12) chron... | ['Blood Loss, Surgical', 'Endothelin-1', 'Female', 'Hepatectomy', 'Humans', 'Intraoperative Period', 'Liver', 'Liver Function Tests', 'Male', 'Middle Aged', 'Portal Pressure', 'Portal Vein', 'Postoperative Period', 'Time Factors'] | 10,423,330 | [['C23.550.414.300', 'C23.550.505.300'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['A03.620'], ['E01.370.372.460'], ['M01.060.116.630'], ['G09.330.380.076.732.650'], ['A07.015.908.670.567'... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of Enamel Deproteinization in Primary Teeth. | OBJECTIVE: To evaluate and compare the topographical features of enamel surface, etched with different materials.STUDY DESIGN: 10 extracted human primary molars were randomly selected and cut and trimmed to 1 mm2. Each group comprised of 10 blocks and the enamel was treated as follows: Group I-35% H3PO4; Group II-5.25%... | ['Acid Etching, Dental', 'Dental Enamel', 'Humans', 'Microscopy, Electron, Scanning', 'Phosphoric Acids', 'Sodium Hypochlorite', 'Tooth, Deciduous'] | 28,937,893 | [['E06.931.475.111'], ['A14.549.167.900.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.029.260.700.675', 'D01.695.625.675'], ['D01.210.465.800', 'D01.650.550.400.800', 'D01.857.750'], ['A14.549.167.860.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complement C5a activation of phospholipase D in human neutrophils. A major route to the production of phosphatidates and diglycerides. | The contribution of phospholipase D (PLD) to the production of phosphatidic acid (PA) and diglyceride (DG) by C5a-stimulated human neutrophils has been studied. Membrane-associated 1-O-alkyl-phosphatidylcholine (alkyl-PC) was double labeled with 3H and 32P by incubating neutrophils with [3H]alkyl-lysoPC and alkyl-[32P]... | ['Alkylation', 'Calcium', 'Complement C5a', 'Cytochalasin B', 'Diglycerides', 'Enzyme Activation', 'Humans', 'In Vitro Techniques', 'Kinetics', 'Neutrophils', 'Phosphatidate Phosphatase', 'Phosphatidic Acids', 'Phosphatidylcholines', 'Phosphatidylethanolamines', 'Phospholipase D', 'Phospholipases', 'Propranolol', 'Reco... | 2,307,846 | [['G02.111.035', 'G02.607.094', 'G03.059'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.124.486.274.024.270', 'D12.776.124.486.274.450.250'], ['D03.633.100.473.231.370', 'D23.946.587.370.370'], ['D10.351.303'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481']... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A free-energy simulation study of a bacterial collagenase inhibitor. | The cis-trans conformational isomerisation of the N-methylated peptide bond of a bacterial collagenases peptide inhibitor (HS-CH2-CH2-CO-Pro-NMe-Ala) has been investigated by molecular dynamics simulations, energy minimisations and free-energy simulations in presence of solvent molecules. The free-energy difference bet... | ['Bacteria', 'Computer Simulation', 'Dipeptides', 'Electrochemistry', 'Hot Temperature', 'Matrix Metalloproteinase Inhibitors', 'Methylation', 'Molecular Structure', 'Protein Conformation', 'Thermodynamics', 'Water'] | 8,045,685 | [['B03'], ['L01.224.160'], ['D12.644.456.345'], ['H01.181.529.307'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D27.505.519.389.745.610'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['G02.111.570', 'G02.466'], ['... | ['Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
A study of stereo microscope measurements based on interpolated feature matching. | Recently, digital stereo microscopes have been becoming increasingly popular in fields such as biomedicine and biotechnology. As such, being able to precisely match left/right feature pairs is critical, which is an important step in stereo matching. We hereby propose a dynamic interpolation method that combines two dim... | ['Algorithms', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Machine Learning', 'Microscopy', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Signal Processing, Computer-Assisted', 'Subtraction Technique'] | 26,405,911 | [['G17.035', 'L01.224.050'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['L01.399.750'], ['E05.318.370.725', 'E05.337... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley. | Polysaccharides derived from fungi and plants have been increasingly used as dietary supplement with therapeutic intention for cancer. However, whether these polysaccharides from different sources and structures can elicit similar immunological effects remain unknown. This study aims to investigate and compare the effe... | ['CD4 Antigens', 'Cell Proliferation', 'Cells, Cultured', 'Dendritic Cells', 'Endocytosis', 'Hordeum', 'Humans', 'Interleukin-10', 'Interleukin-12', 'Interleukin-2 Receptor alpha Subunit', 'Leukocytes, Mononuclear', 'Lymphotoxin-alpha', 'Polysaccharides', 'Reishi', 'T-Lymphocytes'] | 17,606,977 | [['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['G04.417'], ['B01.650.940.800.575.912.250.822.481'], ['B01.050.150.900.64... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short-term Results From a Training Program to Improve Organ Donation in Uncontrolled Donation After Circulatory Death. | BACKGROUND: In all organ transplantation programs, election of the proper protocol relies primarily on the professionals involved in the detection of potential donors. The objective of our study was to assess the impact of a series of prehospital training sessions, as well as to develop several positive feedback strate... | ['Death', 'Donor Selection', 'Education', 'Emergency Medical Services', 'Emergency Medicine', 'Female', 'Health Plan Implementation', 'Humans', 'Male', 'Middle Aged', 'Program Evaluation', 'Spain', 'Tissue and Organ Procurement'] | 29,579,843 | [['C23.550.260'], ['E04.936.537.500', 'N02.421.911.600'], ['I02'], ['N02.421.297'], ['H02.403.250'], ['N03.349.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['Z01.542.846'], ['N02.421.911']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Primary eosinophilic granuloma of the frontal lobe. | The clinical symptoms, pathological findings and surgical treatment of a case of primary frontal lobe eosinophilic granuloma are presented. Initially a frontal mass was detected that clinically seemed like a low-growth tumor. After operation, the histological, cytochemical and ultrastructural studies showed positive ac... | ['Adult', 'Brain Diseases', 'Brain Neoplasms', 'Diagnosis, Differential', 'Eosinophilic Granuloma', 'Female', 'Frontal Lobe', 'Humans', 'Male'] | 7,210,500 | [['M01.060.116'], ['C10.228.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.171'], ['C05.116.391', 'C08.381.483.375.500', 'C15.378.553.231.348', 'C15.604.250.400.360', 'C23.550.382.250'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activity Disengagement: Understanding Challenges and Opportunities for Reengagement. | Although maintaining engagement in activities has a positive influence on our health and wellbeing as we age, many programs that serve older adults struggle with getting participation in the programs they offer. This study sought to explore activity disengagement among older adults in a senior housing community and ide... | ['Adult', 'Aged', 'Attitude to Health', 'Female', 'Geriatric Assessment', 'Health Behavior', 'Health Promotion', 'Humans', 'Leisure Activities', 'Male', 'Occupational Therapy', 'Personal Satisfaction'] | 29,097,960 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
ED endovaginal pelvic ultrasound in nonpregnant women with right lower quadrant pain. | INTRODUCTION: We hypothesized that emergency physician-performed endovaginal ultrasound (EVUS) would change diagnostic decision making in nonpregnant women with right lower quadrant (RLQ) pain.METHODS: A prospective cohort of female patients was enrolled at an urban emergency department (ED). Inclusion criteria were RL... | ['Abdominal Pain', 'Adnexal Diseases', 'Adolescent', 'Adult', 'Aged', 'Appendicitis', 'Decision Making', 'Diagnosis, Differential', 'Emergency Service, Hospital', 'Female', 'Genitalia, Female', 'Humans', 'Middle Aged', 'Ovary', 'Prospective Studies', 'Ultrasonography', 'Uterus', 'Vagina'] | 18,082,786 | [['C23.888.592.612.054', 'C23.888.821.030'], ['C13.351.500.056'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['F02.463.785.373'], ['E01.171'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['A05.360.319'], ['B01.050.150.... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bronchial hyperresponsiveness is a common feature in patients with chronic urticaria. | BACKGROUND: Chronic urticaria (CU) is a skin disorder characterized by long-lasting release of histamine, and sometimes leukotrienes, from both mast cells and basophils. Although both these substances are potent inductors of contraction of airway smooth muscle, pulmonary function and airway hyperresponsiveness have not... | ['Adult', 'Aged', 'Aged, 80 and over', 'Asthma', 'Bronchial Hyperreactivity', 'Case-Control Studies', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Methacholine Chloride', 'Middle Aged', 'Respiratory Function Tests', 'Urticaria'] | 16,599,244 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C08.127.210'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.877.88... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lost in transition: child to adult cancer services for young people. | Cancer nursing care across the UK has dramatically improved for children and young people with cancer over the past 20 years (Department of Health, 2007). Around 70% of young people diagnosed with cancer survive into adulthood, albeit with long-term health complications (Scottish Government, 2012). This raises the cont... | ['Adolescent', 'Adult', 'Child', 'Continuity of Patient Care', 'Humans', 'Neoplasms', 'United Kingdom'] | 24,335,869 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['Z01.542.363']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Recurrent amplification in the 22q11 region in laryngeal squamous cell carcinoma results in overexpression of the CRKL but not the MAPK1 oncogene. | Thirteen laryngeal squamous cell carcinoma cell lines were recently studied by array comparative genomic hybridization (array-CGH) in order to identify recurrent DNA copy number alterations in the tumor genome. A highly amplified region 22q11.2 was found in two of the thirteen cell lines. Two established oncogenes CRKL... | ['Adaptor Proteins, Signal Transducing', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Chromosomes, Human, Pair 22', 'Female', 'Gene Amplification', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', 'Mitogen-Activated Protein Kinase 1', 'Ne... | 21,896,986 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.187.520.300.505.515', 'G05.360.162.520.300.505.515'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['G05.308.3... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Pleomorphic adenoma as a parapharyngeal tumor. The role of the CT in differential diagnosis]. | We described 2 cases of pleomorphic adenoma as parapharyngeal masses, one of the deep lobule of the parotid gland and the other one in palatine accessory salivary glands. After computed tomography (CAT) we made the anatomopathological diagnosis of pleomorphic adenoma with fine needle aspiration. We discuss about the ro... | ['Adenoma, Pleomorphic', 'Aged', 'Diagnosis, Differential', 'Female', 'Humans', 'Parotid Neoplasms', 'Salivary Gland Neoplasms', 'Tomography, X-Ray Computed'] | 9,549,150 | [['C04.557.435.090', 'C04.557.470.035.155'], ['M01.060.116.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770', 'C07.465.815.718.589'], ['C04.588.443.591.824', 'C07.465.530.824', 'C07.465.815.718'], ['E01.370.350.350.810', 'E01.37... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. | The transcription factor sterol regulatory element binding protein (SREBP)-1c is intimately involved in the regulation of lipid and glucose metabolism. To investigate whether mutations in this gene might contribute to insulin resistance, we screened the exons encoding the aminoterminal transcriptional activation domain... | ['Base Sequence', 'CCAAT-Enhancer-Binding Proteins', 'Case-Control Studies', 'Cholesterol', 'DNA Primers', 'DNA-Binding Proteins', 'Diabetes Mellitus, Type 2', 'European Continental Ancestry Group', 'Female', 'Genetic Variation', 'Humans', 'Insulin Resistance', 'Introns', 'Male', 'Polymorphism, Single Nucleotide', 'Ref... | 14,988,272 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D13.695.578.424.450.275', 'D27.720.47... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Physical exercise regulates neural stem cells proliferation and migration via SDF-1á/CXCR4 pathway in rats after ischemic stroke. | Physical exercise is beneficial to functional recovery after stroke. But its underling mechanism is still unknown. It is reported that neural stem cells (NSCs) proliferation, migration and differentiation play an important role in recovery following stroke, furthermore, stromal cell derived factor-1á (SDF-1á) and its c... | ['Animals', 'Brain', 'Brain Ischemia', 'Cell Movement', 'Cell Proliferation', 'Chemokine CXCL12', 'Male', 'Neural Stem Cells', 'Physical Conditioning, Animal', 'Rats', 'Rats, Wistar', 'Receptors, CXCR4', 'Signal Transduction', 'Stroke'] | 25,010,020 | [['B01.050'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374.200.120.600', 'D12.776.467.374.200.120.600', 'D23.125.300.120.600', 'D23.469.200.120.600', 'D23.529.374.200.120.600'], ['A11.872.653'], ['G11.427.410.698.2... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis. | OBJECTIVE: To see how initial differences in subchondral bone phenotype influence the development of cartilage damage and changes in subchondral bone architecture in an osteoarthritis (OA)-induced mouse model.METHOD: Intra-articular collagenase injections (right knee joint) and saline controls (left knee joint) were ap... | ['Age Factors', 'Animals', 'Arthritis, Experimental', 'Cartilage, Articular', 'Disease Models, Animal', 'Epiphyses', 'Male', 'Mice', 'Mice, Inbred Strains', 'Microbial Collagenase', 'Osteoarthritis', 'Phenotype', 'Stifle', 'Tibia'] | 17,900,935 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['A02.165.407.150', 'A02.835.583.192'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A02.835.232.251'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'... | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The T. cruzi trans-sialidase induces PC12 cell differentiation via MAPK/ERK pathway. | The trans-sialidase (TS) of Trypanosoma cruzi induces survival and differentiation of neuronal and glial cells. This mechanism underlying survival is via phosphatidylinositol 3-kinase (PI3K) but how TS promotes neuronal differentiation remained to be determined. Here we show that TS-induced neurite outgrowth in PC12 ce... | ['Animals', 'Cell Differentiation', 'Cell Survival', 'Enzyme Inhibitors', 'Flavonoids', 'Glycoproteins', 'Immunoblotting', 'MAP Kinase Kinase 1', 'Mitogen-Activated Protein Kinase Kinases', 'Mitogen-Activated Protein Kinases', 'Nerve Growth Factor', 'Nerve Growth Factors', 'Nervous System', 'Neuraminidase', 'Neurites',... | 11,726,780 | [['B01.050'], ['G04.152'], ['G04.346'], ['D27.505.519.389'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D09.400.430', 'D12.776.395'], ['E05.478.566.320', 'E05.601.470.320'], ['D08.811.913.696.620.682.700.565.100', 'D08.811.913.696.620.682.725.200.100', 'D12.644.360.440.100', 'D12.776.476.440.100'], ['D08... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-Time Analysis of Ambient Organic Aerosols Using Aerosol Flowing Atmospheric-Pressure Afterglow Mass Spectrometry (AeroFAPA-MS). | Organic compounds contribute to a major fraction of atmospheric aerosols and have significant impacts on climate and human health. However, because of their chemical complexity, their measurement remains a major challenge for analytical instrumentation. Here we present the development and characterization of a new soft... | ['Aerosols', 'Atmospheric Pressure', 'Computer Systems', 'Humans', 'Ions', 'Mass Spectrometry', 'Organic Chemicals'] | 25,861,027 | [['D20.280.055', 'D26.255.165.055'], ['G16.500.750.274', 'N06.230.300.100.185'], ['L01.224.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['E05.196.566'], ['D02']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Exploring the denaturation of whey proteins upon application of moderate electric fields: a kinetic and thermodynamic study. | Thermal processing often results in disruption of the native conformation of whey proteins, thus affecting functional properties. The aim of this work was to evaluate the effects of moderate electric fields on denaturation kinetics and thermodynamic properties of whey protein dispersions at temperatures ranging from 75... | ['Animals', 'Cattle', 'Electricity', 'Kinetics', 'Milk Proteins', 'Protein Denaturation', 'Thermodynamics', 'Whey Proteins'] | 21,932,854 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.358.500.249'], ['G01.374.661', 'G02.111.490'], ['A12.790.520', 'D12.776.256.159.750', 'G07.203.300.428.159.812', 'J02.500.350.525.520', 'J02.500.428.159.750'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G01.906'], ['A12.790.520.500', 'A12.790.760.500',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Prognostic significance of silent ischemia. | This study examined the prognostic predictors in 521 patients with angiographic evidence of coronary artery disease (CAD). All patients underwent exercise single-photon emission computed tomographic thallium imaging. The patients were divided into those with symptomatic ischemia defined as reversible thallium defects, ... | ['Adult', 'Aged', 'Exercise Test', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Prognosis', 'Survival Rate', 'Thallium Radioisotopes', 'Tomography, Emission-Computed, Single-Photon'] | 9,420,727 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647', 'C14.907.585'], ['E01.789'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850.520.308.985.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence and incidence of Q-wave unrecognized myocardial infarction in general population: Diagnostic value of the electrocardiogram. The REGICOR study. | BACKGROUND: Diagnosis of unrecognized myocardial infarction (UMI) remains an open question in epidemiological and clinical studies, inhibiting effective secondary prevention of myocardial infarction. We aimed to determine the prevalence and incidence of Q-wave UMI in asymptomatic individuals aged 35 to 74years, and to ... | ['Adult', 'Aged', 'Cohort Studies', 'Cross-Sectional Studies', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Population Surveillance', 'Prevalence', 'Registries'] | 27,744,207 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prognostic model for predicting overall survival in children and adolescents with rhabdomyosarcoma. | BACKGROUND: The purpose of this study was to develop a prognostic model for the survival of pediatric patients with rhabdomyosarcoma (RMS) using parameters that are measured during routine clinical management.METHODS: Demographic and clinical variables were evaluated in 1679 pediatric patients with RMS registered in th... | ['Adolescent', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Neoplasm Staging', 'Nomograms', 'Prognosis', 'Proportional Hazards Models', 'Rhabdomyosarcoma', 'Survival Analysis', 'Survival Rate', 'Treatment Outcome'] | 25,189,734 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.789.625'], ['E01.789.650', 'E05.318.740.500.625', 'E05.599.835.895', 'G17.582', 'N05.715.360.750.530.530', 'N06.850.520.830.500.625... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification and quantitative analysis of hydroxy-eicosatetraenoic acids in rat brains exposed to regional ischemia. | To clarify possible roles in the pathogenesis of ischemic brain edema, identification and quantitative analysis of hydroxy-eicosatetraenoic acids (HETEs) in rat brains exposed to middle cerebral artery occlusion were carried out using high-performance liquid chromatography. Rat brain sampling was done by in situ freezi... | ['Animals', 'Brain', 'Brain Ischemia', 'Chromatography, High Pressure Liquid', 'Hydroxyeicosatetraenoic Acids', 'Male', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 3,564,108 | [['B01.050'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E05.196.181.400.300'], ['D10.251.355.255.100.300', 'D10.251.355.310.166.550'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of ganglion using hypertonic saline as sclerosant. | Twenty-nine patients with ganglion of the wrist were treated in this hospital using hypertonic saline as sclerosant. All patients were treated as outpatients. Under aseptic conditions, the ganglia were aspirated using #18 hyperdermic needle. A mixture of 2 cc of hypertonic saline and 1 cc 1% xylocaine were injected int... | ['Adult', 'Female', 'Humans', 'Injections, Intralesional', 'Male', 'Middle Aged', 'Recurrence', 'Saline Solution, Hypertonic', 'Suction', 'Synovial Cyst', 'Treatment Outcome', 'Wrist Joint'] | 12,769,298 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.430'], ['M01.060.116.630'], ['C23.550.291.937'], ['D26.776.314.890'], ['E04.237.890'], ['C04.182.867'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['A02.835.583.405.930']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of the unique intron-exon junctions of Euglena gene(s) encoding the polyprotein precursor to the light-harvesting chlorophyll a/b binding protein of photosystem II. | The precursor to the Euglena light harvesting chlorophyll a/b binding protein of photosystem II (LHCPII) is a polyprotein containing multiple copies of LHCPII covalently joined by a decapeptide linker. cDNA and genomic clones encoding the 5' and 3' end of a 6.6 kb LHCPII mRNA were sequenced. A 3.1 kb genomic region enc... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'DNA, Complementary', 'Euglena gracilis', 'Gene Expression', 'Genes, Plant', 'Introns', 'Light-Harvesting Protein Complexes', 'Molecular Sequence Data', 'Photosynthesis', 'Photosynthetic Reaction Center Complex Proteins', 'Photosystem II Protein Complex', 'Plant Prote... | 7,838,730 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.268.250.320.418'], ['G05.297'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.024.220.400', 'G05.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Decrease in serum testosterone levels with maximal intensity swimming exercise in trained male and female swimmers. | Circulating testosterone levels have generally been reported to increase during short term, intense running or bicycle ergometer exercise. Swimming differs from such activity because of the strenuous arm activity and because it is conducted in a liquid medium in the horizontal position with the weight totally supported... | ['Adolescent', 'Blood Volume', 'Female', 'Humans', 'Hydrocortisone', 'Lactates', 'Lactic Acid', 'Male', 'Oxygen Consumption', 'Physical Exertion', 'Swimming', 'Testosterone'] | 3,582,275 | [['M01.060.057'], ['G09.188.130', 'G09.330.380.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['G03.680'], ['G11.427.683'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Genetic investigation of the patrilineal kinship structure of early medieval Ireland. | A previous study of Irish Y-chromosomes uncovered a likely patrilineal kinship basis to the most prominent early Irish tribal entity/kingdom, the U? N?ill, who dominated the North of the Island during the early medieval period (600-1,000 AD). However, it is unknown to what extent this was a general feature of the multi... | ['Chromosomes, Human, Y', 'Gene Frequency', 'Genetic Variation', 'Genetics, Population', 'Geography', 'History, Medieval', 'Humans', 'Ireland', 'Male', 'Models, Genetic', 'Names', 'Pedigree', 'Population Groups'] | 18,350,585 | [['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['G05.330'], ['G05.365'], ['H01.158.273.343.335'], ['H01.277.500'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.467', 'Z01.639.587'], ['E05.599.395.397'], ['L01.559.598.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
[The structure of somatic pathology according to sex in hospitalized pediatric patients in Armenia]. | The aim of the investigation was the analyzes of somatic pathology according to sex in hospitalized pediatric patients in Armenia in 2003-2009. The study showed the prevail of respiratory diseases, congenital abnormalities, defects and chromosomal abnormalities and certain states arising in the perinatal period. The st... | ['Adolescent', 'Armenia', 'Child', 'Child, Preschool', 'Digestive System Diseases', 'Female', 'Genetic Diseases, Inborn', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Respiratory Tract Diseases', 'Urogenital Abnormalities'] | 22,859,448 | [['M01.060.057'], ['Z01.542.900.099', 'Z01.542.931.099', 'Z01.586.035.150', 'Z01.586.950.099'], ['M01.060.406'], ['M01.060.406.448'], ['C06'], ['C16.320'], ['N02.278.421.556.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C08'], ['C12.706', 'C13.351.875', 'C16.131.939']] | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cytoplasmic Ca(2+) concentration changes evoked by cholinergic stimulation in primary astrocyte cultures prepared from the rat cochlear nucleus. | The involvement of astrocytes in the cholinergic modulation of the cochlear nucleus has been studied using primary astrocyte cultures prepared from this nucleus. The cells were loaded with the membrane permeable form of the fluorescent Ca(2+) indicator Fluo-4, and carbachol-induced Ca(2+) concentration increases were m... | ['Animals', 'Astrocytes', 'Calcium', 'Calcium Signaling', 'Carbachol', 'Cells, Cultured', 'Cholinergic Agonists', 'Cholinergic Antagonists', 'Cochlear Nucleus', 'Cytoplasm', 'Immunohistochemistry', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Rats', 'Receptor, Muscarinic M1', 'Receptor, Muscarinic M3'] | 19,497,356 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['A11.251'], ['D27.505.519.625.120.140', 'D27.505.696.577.120.140'], ['D27.505.519.625.120.200', 'D27.50... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression and roles of pannexins in ATP release in the pituitary gland. | Pannexins are a newly discovered three-member family of proteins expressed in the brain and peripheral tissues that belong to the superfamily of gap junction proteins. However, in mammals pannexins do not form gap junctions, and their expression and function in the pituitary gland have not been studied. Here we show th... | ['Adenosine Triphosphate', 'Animals', 'Cell Line', 'Connexins', 'Female', 'Gene Expression Regulation', 'Humans', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Pituitary Gland', 'Rats', 'Rats, Sprague-Dawley'] | 21,467,198 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.251.210'], ['D12.776.543.585.250'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.776.631'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Antithrombotic treatment and characteristics of elderly patients with non-valvular atrial fibrillation hospitalized at Internal Medicine departments. NONAVASC registry. | BACKGROUND AND OBJETIVES: The prevalence of non-valvular atrial fibrillation (NVAF) increases with the patient's age and is associated with high morbi-mortality rates. The main goal of this study was to describe the characteristics of hospitalized elderly patients with NVAF and to identify the clinical and functional f... | ['Aged', 'Aged, 80 and over', 'Anticoagulants', 'Atrial Fibrillation', 'Clinical Decision-Making', 'Cross-Sectional Studies', 'Drug Utilization', 'Female', 'Fibrinolytic Agents', 'Hospitalization', 'Humans', 'Internal Medicine', 'Male', 'Platelet Aggregation Inhibitors', "Practice Patterns, Physicians'", 'Prospective S... | 27,993,408 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.502.119'], ['C14.280.067.198', 'C23.550.073.198'], ['E01.055'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.452.706.477'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['E02.760.400', 'N02.421... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
A controlled clinical study on the new topical dosage form of DHEP plasters in patients suffering from localized inflammatory diseases. | In this clinical study the efficacy and the tolerability of a new topical formulation, DHEP plaster, have been evaluated. The plaster consists of an auto-adhesive medicated gauze pad of standard dimensions (10 x 15 cm) containing 180 mg DHEP. The reference drug was a well-known topical drug, diclofenac diethylammonium ... | ['Administration, Cutaneous', 'Arthritis', 'Diclofenac', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Tendinopathy'] | 8,112,205 | [['E02.319.267.120.060'], ['C05.550.114'], ['D02.241.223.601.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['C05.651.869', 'C26.874.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhancing course grades and evaluations using distance education technologies. | Delivering appropriate amounts of course content using appropriate methods is a concern for nursing faculty. To address this problem, webcasting, Camtasia, and Wimba Live Classroom were evaluated for impact on course grades and student evaluations in a medical-surgical nursing course. The addition of Camtasia resulted ... | ['Curriculum', 'Education, Distance', 'Education, Nursing, Baccalaureate', 'Educational Measurement', 'Educational Technology', 'Humans', 'Nursing Education Research', 'Nursing Evaluation Research', 'Nursing Methodology Research', 'Perioperative Nursing'] | 23,608,913 | [['I02.158'], ['I02.195'], ['I02.358.462.316'], ['I02.399'], ['J01.897.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.390.413', 'H02.478.395.413', 'I02.358.462.612', 'N04.590.233.508.613.413'], ['H01.770.644.145.390.432', 'H02.478.395.432', 'N04.590.233.508.613.432'], ['H01.770.644.145.390.63... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Molecular profiling improves classification and prognostication of nodal peripheral T-cell lymphomas: results of a phase III diagnostic accuracy study. | PURPOSE: The differential diagnosis among the commonest peripheral T-cell lymphomas (PTCLs; ie, PTCL not otherwise specified [NOS], angioimmunoblastic T-cell lymphoma [AITL], and anaplastic large-cell lymphoma [ALCL]) is difficult, with the morphologic and phenotypic features largely overlapping. We performed a phase I... | ['Diagnosis, Differential', 'Female', 'Formaldehyde', 'Humans', 'Lymphoma, T-Cell, Peripheral', 'Male', 'Paraffin Embedding', 'Prognosis', 'Survival Analysis', 'Tissue Fixation', 'Transcriptome'] | 23,857,971 | [['E01.171'], ['D02.047.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480.750.825', 'C15.604.515.569.480.750.825', 'C20.683.515.761.480.750.825'], ['E01.370.225.500.620.760.440.610', 'E01.370.225.750.600.760.440.610', 'E05.200.500.620.760.440.610', 'E05.200.750.600.760.440.610'], ['E01.789'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Some theoretical models in the study of health behaviour: implications for health systems in India. | This paper attempts to highlight some of the presently accepted models of health, behaviour and their usage in explaining illness, sickness and utilisation behaviour. The limitations of each of the model have also been described. Finally an attempt has been made to visualise the applicability of such models on Indian h... | ['Health Services', 'India', 'Models, Theoretical', 'Sociology, Medical'] | 10,260,951 | [['N02.421'], ['Z01.252.245.393'], ['E05.599'], ['F04.096.879.757.400', 'H02.790', 'I01.880.859']] | ['Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
T4-induced activity required for specific cleavage of a bacteriophage protein in vitro. | We have examined the acid-soluble products formed during incubation of labeled substrate protein from T4-infected cells with unlabeled phage-infected cell extracts. If the substrate protein is prepared from cells infected with a T4 mutant blocked in cleavage of phage head precursor proteins, the products formed in vitr... | ['Carbon Radioisotopes', 'Cell-Free System', 'Chromatography', 'Coliphages', 'Escherichia coli', 'Lysine', 'Molecular Weight', 'Mutation', 'Peptide Biosynthesis', 'Peptide Hydrolases', 'Peptides', 'Pronase', 'Protein Denaturation', 'Protein Precursors', 'Tritium', 'Viral Proteins'] | 4,589,856 | [['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.284.835.168'], ['E05.196.181'], ['B04.123.205'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['G02.494'], ['G05.365.590'], ['G02.111.660', 'G03.734'], ['D08.811.277.656'], ['D12.6... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of HCV and GBV-CHGV RNA in peripheral blood mononuclear cells of patients with chronic type C hepatitis. | Hepatitis C virus (HCV) and hepatitis G virus (HGV) viraemia were investigated by RT-PCR protocols in peripheral blood mononuclear cells (PBMC) of 22 patients with chronic type C hepatitis. Samplings were at basal and 4-8 months after a 12 month period of treatment with interferon-alpha. A plus strand of HCV in PBMC wa... | ['Flaviviridae', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Interferon-alpha', 'Leukocytes, Mononuclear', 'Reverse Transcriptase Polymerase Chain Reaction', 'Viremia'] | 11,034,441 | [['B04.820.578.344'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. | The vast majority of urinary tract infections are caused by strains of uropathogenic Escherichia coli that encode filamentous adhesive organelles called type 1 pili. These structures mediate both bacterial attachment to and invasion of bladder epithelial cells. However, the mechanism by which type 1 pilus-mediated bact... | ['Acute Disease', 'Animals', 'Cell Line', 'Cystitis', 'Disease Models, Animal', 'Escherichia coli', 'Escherichia coli Infections', 'Female', 'Intracellular Fluid', 'Mice', 'Mice, Inbred C57BL', 'Urinary Bladder', 'Urinary Tract Infections'] | 11,402,001 | [['C23.550.291.125'], ['B01.050'], ['A11.251.210'], ['C12.777.829.495', 'C13.351.968.829.495'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['A11.284.430.429', 'A11.284.835.450', 'A12.207.515'], ['B01.050.150.900.649.313.992.635.505... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of febuxostat on coronary artery endothelial dysfunction in patients with coronary artery disease: A phase 4 randomized, placebo-controlled, double-blind, crossover trial. | BACKGROUND: The xanthine oxidase (XO) system is a significant source of vascular oxidative stress, which is believed to impair endothelial function, an important contributor to atherosclerotic disease. We tested whether febuxostat, a potent XO inhibitor, improves coronary endothelial function (CEF) in patients with sta... | ['Coronary Artery Disease', 'Coronary Vessels', 'Cross-Over Studies', 'Double-Blind Method', 'Drug Monitoring', 'Endothelium, Vascular', 'Febuxostat', 'Female', 'Gout Suppressants', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Oxidative Stress', 'Treatment Outcome', 'Xanthine Oxidase'] | 29,447,788 | [['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.520.200'], ['A07.015.700.500', 'A10.272.491.3... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Oculocerebral malignant non-Hodgkin lymphoma. A report of 5 cases]. | Five patients, age 35 to 77, with histologically proven malignent ocular non-Hodgkin's lymphoma (previously known as reticulum cell sarkoma) are presented. The clinical ocular findings (vitreous infiltrates, retinal infiltrates, anterior uveitis) were initially misinterpreted as "panuveitis". The usual antiinflammatory... | ['Brain Neoplasms', 'Combined Modality Therapy', 'Diagnosis, Differential', 'Eye Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Panuveitis'] | 1,886,378 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E02.186'], ['E01.171'], ['C04.588.364', 'C11.319'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.48... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The relation between the after-negative potential of the pattern electroretinogram and the visually evoked cortical potential. | The relationship between the after-negative potential of the pattern electroretinogram (PERG) and the visually evoked cortical potential (VECP) was studied. The PERG was recorded through the use of Toray's high water content, soft contact lens electrode. The PERG consisted of an initial positive potential, a subsequent... | ['Contact Lenses', 'Ear', 'Electrodes', 'Electroretinography', 'Evoked Potentials, Visual', 'Humans', 'Reaction Time', 'Scalp'] | 3,743,333 | [['E07.632.500.276'], ['A01.456.313', 'A09.246'], ['E07.305.250'], ['E01.370.380.225', 'E01.370.405.270'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['A01.456.810']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe falciparum malaria complicated by prolonged haemolysis and rhinomaxillary mucormycosis after parasite clearance: a case report. | BACKGROUND: Severe falciparum malaria may be complicated by prolonged haemolysis and recurrent fever after parasite clearance. However, their respective etiologies are unclear and challenging to diagnose. We report the first case of severe falciparum malaria followed by prolonged haemolytic anaemia and rhinomaxillary m... | ['Adult', 'Anemia, Hemolytic', 'Antimalarials', 'Ceftriaxone', 'Coinfection', 'Humans', 'Malaria, Falciparum', 'Male', 'Maxillary Diseases', 'Mucormycosis', 'Opportunistic Infections', 'Parasitemia', 'Rhinitis', 'Severity of Illness Index'] | 26,634,340 | [['M01.060.116'], ['C15.378.071.141'], ['D27.505.954.122.250.100.085'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['C01.218'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530.650', 'C01.920.875.650'], ['C05.500.693', 'C07.320.660'], ['C01.1... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Early warning signs in misrecognized secondary pediatric psychotic disorders: a systematic review. | Childhood psychotic symptoms are not uncommon, but lack an evidence-based diagnostic approach. Hallucinations, delusions and other psychotic symptoms, without endangered vital symptoms, can be the result of a primary psychiatric disorder or can be the presenting symptom of an underlying somatic disease. It is important... | ['Adolescent', 'Child', 'Delusions', 'Female', 'Hallucinations', 'Humans', 'Male', 'Prospective Studies', 'Psychotic Disorders'] | 30,054,738 | [['M01.060.057'], ['M01.060.406'], ['F01.145.126.200'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['F03.700.675']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prospective preoperative determination of mucinous pancreatic cystic neoplasms. | BACKGROUND: Optimal management of pancreatic cystic neoplasms includes identification and resection of mucinous neoplasms. This study was performed to assess the accuracy of preoperative variables in determining a mucinous lesion.METHODS: Patients referred for a cystic neoplasm were prospectively assessed by presenting... | ['Adenocarcinoma, Mucinous', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms, Cystic, Mucinous, and Serous', 'Pancreatic Neoplasms', 'Retrospective Studies', 'Time Factors'] | 12,407,346 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.470.590'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['E05.318.372.500.500.500', ... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does size matter? Investigating the optimal planning target volume margin for postoperative stereotactic radiosurgery to resected brain metastases. | OBJECTIVE: The optimal margin size in postoperative stereotactic radiosurgery (SRS) for brain metastases is unknown. Herein, the authors investigated the effect of SRS planning target volume (PTV) margin on local recurrence and symptomatic radiation necrosis postoperatively.METHODS: Records of patients who received pos... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain Neoplasms', 'Cohort Studies', 'Craniotomy', 'Female', 'Follow-Up Studies', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Margins of Excision', 'Middle Aged', 'Necrosis', 'Neoplasm Recurrence, Local', 'Patient Care Planning', 'Radiation Injuries', 'Radiosurgery', 'Retrospectiv... | 29,676,690 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.525.190'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An evaluation of bromocriptine in the treatment of Parkinson's disease. | 22 patients entered a double-blind trial to test the efficacy of bromocriptine therapy in patients with Parkinson's disease already established on conventional levodopa therapy. 3 patients on placebo withdrew when no improvement occurred and control became complicated. 4 patients on active drug withdrew because of vari... | ['Aged', 'Bromocriptine', 'Clinical Trials as Topic', 'Double-Blind Method', 'Drug Therapy, Combination', 'Dyskinesia, Drug-Induced', 'Female', 'Hallucinations', 'Humans', 'Levodopa', 'Male', 'Middle Aged', 'Nausea', 'Parkinson Disease'] | 386,307 | [['M01.060.116.100'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.310'], ['C10.228.662.262.500', 'C10.597.350.275', 'C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A two-photon fluorescence-correlation study of lectins interacting with carbohydrated 20 nm beads. | We present results of a two-photon fluorescence-correlation study carried out with glycosylated and untreated 20 nm fluorescing spheres that interacted with the carbohydrate-binding proteins soybean agglutinin (SBA) and concanavalin A (Con A). The assay principle allows protein-carbohydrate binding interactions to be d... | ['Carbohydrates', 'Concanavalin A', 'Microspheres', 'Particle Size', 'Photons', 'Plant Lectins', 'Soybean Proteins', 'Spectrometry, Fluorescence'] | 16,408,309 | [['D09'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['E07.565'], ['G02.712'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['D12.776.503.499', 'D12.776.765.678'], ['D12.776.765.741', 'G07.203.300.428.920.750', 'G07.203.300.850.450.500.750', 'J02.500.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Secondary osteoporosis. Chronic obstructive pulmonary disease:COPD.] | Chronic obstructive pulmonary disease(COPD), an inflammatory disease of the lung mainly caused by cigarette smoking, is a systemic disease associated with various extra-pulmonary comorbidities such as osteoporosis, ischemic heart disease and sarcopenia. Osteoporosis is one of such complications, and the prevalence of v... | ['Bone Density', 'Humans', 'Osteoporosis', 'Pulmonary Disease, Chronic Obstructive', 'Risk Factors', 'Spinal Fractures'] | 30,487,330 | [['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.198.579', 'C18.452.104.579'], ['C08.381.495.389'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['C26.117.500.500', 'C26.404.812']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mutation analysis identifies GUCY2D as the major gene responsible for autosomal dominant progressive cone degeneration. | PURPOSE: Heterozygous mutations in the GUCY2D gene, which encodes the membrane-bound retinal guanylyl cyclase-1 protein (RetGC-1), have been shown to cause autosomal dominant inherited cone degeneration and cone-rod degeneration (adCD, adCRD). The present study was a comprehensive screening of the GUCY2D gene in 27 adC... | ['Codon', 'DNA', 'DNA Mutational Analysis', 'Disease Progression', 'Electroretinography', 'Female', 'Genetic Predisposition to Disease', 'Guanylate Cyclase', 'Haplotypes', 'Humans', 'Male', 'Mutation', 'Pedigree', 'Polymerase Chain Reaction', 'Prognosis', 'Receptors, Cell Surface', 'Retinal Degeneration', 'Rod Cell Out... | 18,487,367 | [['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308'], ['E05.393.760.700.300'], ['C23.550.291.656'], ['E01.370.380.225', 'E01.370.405.270'], ['C23.550.291.687.500', 'G05.380.355'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['G05.380.360'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patterns of care and survival outcomes for laryngeal small cell cancer. | BACKGROUND: To determine practice patterns and outcomes of laryngeal small cell cancer (LSCC) across the United States.METHODS: Patients with LSCC were identified in the National Cancer Database. Overall survival (OS) was compared with Kaplan-Meier analysis and Cox regression.RESULTS: From 2004 to 2014, the 5-year OS f... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Small Cell', 'Chemoradiotherapy', 'Databases, Factual', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', "Practice Patterns, Physicians'", 'Proportional Hazards Models', 'Survival Rate', 'Treatment Outcome', 'United States', 'Y... | 30,785,231 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.380'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['C0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Regional distribution of putative rhythm-generating and pattern-forming components of the mammalian locomotor CPG. | The ventromedial spinal cord of mammals contains a neural network known as the locomotor central pattern generator (CPG) which underlies the basic generation and coordination of muscle activity during walking. To understand how this neural network operates, it is necessary to identify, characterize, and map connectivit... | ['Animals', 'Animals, Newborn', 'Axons', 'Central Pattern Generators', 'Data Interpretation, Statistical', 'Electrophysiological Phenomena', 'Image Processing, Computer-Assisted', 'In Vitro Techniques', 'Interneurons', 'Locomotion', 'Mice', 'Mice, Inbred Strains', 'Neurites', 'Patch-Clamp Techniques', 'Spinal Cord'] | 23,933,310 | [['B01.050'], ['B01.050.050.282'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.511.500'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G07.265'], ['L01.224.308'], ['E05.481'], ['A08.675.358', 'A11.671.358'], ['G07.568.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Induction in vitro of a specific pattern of jejunal propulsive behavior by cholecystokinin. | Experiments were conducted in vitro to determine whether arterial infusion of the C-terminal octapeptide of cholecystokinin (CCK-8) into cat jejunal segments could elicit propulsive behavior when a segment must do hydrostatic work to expel fluid. Oral and aboral ends of jejunal segments, 17 cm in length, were connected... | ['Animals', 'Atropine', 'Cats', 'Gastrointestinal Motility', 'Hexamethonium Compounds', 'Hydrostatic Pressure', 'Jejunum', 'Sincalide', 'Stimulation, Chemical', 'Time Factors'] | 3,985,151 | [['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G10.261.360'], ['D02.092.877.250.592', 'D02.675.276.558.592'], ['G01.374.715.352'], ['A03.556.124.684.500', 'A03.556.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gliclazide decreases low-density lipoprotein oxidation and monocyte adhesion to the endothelium. | Increasing evidence implicates oxidized low-density lipoprotein (LDL) and advanced glycation end products (AGE) in the atherogenesis associated with diabetes mellitus. In the present study, we examined the in vitro effects of gliclazide on LDL oxidation and monocyte adhesion to endothelial cells induced by oxidized LDL... | ['Adult', 'Cell Adhesion', 'Cells, Cultured', 'Diabetes Mellitus, Type 2', 'Endothelium, Vascular', 'Female', 'Gliclazide', 'Humans', 'Hypoglycemic Agents', 'Lipoproteins, LDL', 'Male', 'Monocytes', 'Oxidation-Reduction'] | 10,693,915 | [['M01.060.116'], ['G04.022'], ['A11.251'], ['C18.452.394.750.149', 'C19.246.300'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.065.950.828.475', 'D02.886.590.795.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D10.532.515', 'D12.776.521.550'], ['A11.118.637.555.652', 'A11.148.580', 'A1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
First-in-human valve-in-valve implantation of a 20 mm balloon expandable transcatheter heart valve. | An 86-year-old lady with recurrent admissions for heart failure due to a severely regurgitant aortic bioprosthesis (SJM Epic 19 mm) was not a candidate for re-operation due to age and frailty. Her small ilio-femoral arteries precluded a transfemoral transcatheter valve-in-valve (VIV) approach. The small internal diamet... | ['Aged, 80 and over', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Aortic Valve Stenosis', 'Balloon Valvuloplasty', 'Bioprosthesis', 'Cardiac Catheterization', 'Echocardiography, Transesophageal', 'Female', 'Fluoroscopy', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Hemodynamics', 'Humans', 'Pros... | 22,821,872 | [['M01.060.116.100.080'], ['A07.541.510.110'], ['C14.280.484.048.500'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E02.148.108', 'E05.157.125'], ['E07.695.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E01.370.350.700... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inertial control as novel technique for in vitro gait simulations. | In vitro gait simulations are a preferential platform to study new intervention techniques or surgical procedures as they allow studying the isolated effect of surgical interventions. Commonly, simulations are performed by applying pre-defined setpoints for the kinetics and kinematics on all degrees of freedom (DOFs) o... | ['Ankle Joint', 'Arthrodesis', 'Arthroplasty, Replacement, Ankle', 'Biomechanical Phenomena', 'Foot', 'Gait', 'Humans', 'Kinetics', 'Models, Biological', 'Movement'] | 25,498,365 | [['A02.835.583.378.062'], ['E04.555.100'], ['E04.555.110.110.010', 'E04.650.110.010', 'E04.680.101.110.010'], ['G01.154.090', 'G01.374.089'], ['A01.378.610.250'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.599.395'], ['G07.568',... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regional alterations of brain catecholamines by lead ingestion in adult rats. Influence of dietary calcium. | The alterations in steady-state dopamine (DA) and norepinephrine (NE) content of hypothalamus-median eminence (HME) and striatum (STR) were measured in adult female rats fed normal calcium (1.2%) or low calcium (0.005%) diets for 4 weeks and exposed to lead via drinking water containing lead acetate (0.032, 0.32, and 3... | ['Animals', 'Body Weight', 'Brain', 'Calcium, Dietary', 'Catecholamines', 'Corpus Striatum', 'Dopamine', 'Female', 'Hypothalamus', 'Lead Poisoning', 'Median Eminence', 'Norepinephrine', 'Rats', 'Rats, Inbred Strains'] | 7,115,079 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['D01.146.395'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.65... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ovulation induction with pulsatile luteinizing releasing hormone in women with clomiphene citrate-resistant polycystic ovary-like disease: clinical results. | Eighty-four treatment units were given to 11 women with clomiphene citrate-resistant polycystic ovarian disease (PCOD). PCOD was defined as oligomenorrhea elevated luteinizing hormone (LH), normal follicle-stimulating hormone (FSH), and preference-elevated androgens. Luteinizing-releasing hormone (LRH) was administered... | ['17-Ketosteroids', 'Adult', 'Androstenedione', 'Anovulation', 'Clomiphene', 'Drug Resistance', 'Estradiol', 'Estrogens', 'Evaluation Studies as Topic', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Humans', 'Luteal Phase', 'Luteinizing Hormone', 'Ovulation Induction', 'Polycystic Ovary S... | 3,096,792 | [['D04.210.500.578.502', 'D06.472.040.502'], ['M01.060.116'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['C13.351.500.056.630.050', 'C19.391.630.050', 'G08.686.784.690.080'], ['D02.455.426.559.389.150.700.125'], ['G07.690.773.984'], ['D04.210.500.365.415.2... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Persistence of fetal bovine serum proteins in human keratinocytes. | Cultured human keratinocytes are used for skin grafts, but their success is limited by late graft loss. Development of antibody to fetal bovine serum (FBS) protein used in culture media for in vitro keratinocyte growth has been identified. The persistence of FBS antigen in skin grafts is important in the induction of t... | ['Animals', 'Antigens, Heterophile', 'Blood Proteins', 'Burns', 'Cell Survival', 'Cells, Cultured', 'Culture Media', 'Enzyme-Linked Immunosorbent Assay', 'Graft Rejection', 'Humans', 'Immune Tolerance', 'Keratinocytes', 'Serum Albumin, Bovine'] | 2,286,603 | [['B01.050'], ['D23.050.244'], ['D12.776.124'], ['C26.200'], ['G04.346'], ['A11.251'], ['D27.720.470.305', 'E07.206'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Potential biomarkers of bortezomib activity in mantle cell lymphoma from the phase 2 PINNACLE trial. | Immunohistochemical analyses of archival tumor specimens were used for pre-planned exploratory analyses of protocol-specified candidate biomarkers of bortezomib activity in 73 patients with relapsed/refractory mantle cell lymphoma in the phase 2 PINNACLE study. Consistent with other studies, elevated Ki-67 was a marker... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Biomarkers, Tumor', 'Boronic Acids', 'Bortezomib', 'Cyclin-Dependent Kinase Inhibitor p27', 'Female', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Lymphoma, Mantle-Cell', 'Male', 'Middle Aged', 'NF-kappa B', 'Proteasome Endopeptidase Comple... | 20,572,799 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['D23.101.140'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['D01.029.260.110.500', 'D01.132.285.500', 'D02.203.200.500', 'D03.383.679.450'], ['D12.644.360.225.600', 'D12.776.167.187.600', 'D12.776.476.225.600', 'D12.776.624.77... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pharmaceutical analysis of medication orders in health care facilities: A France-Quebec comparison]. | OBJECTIVES: The pharmaceutical analysis of drug prescriptions is one of the key steps in the drug circuit. This mandatory regulatory practice in France and Quebec is based on national standards. The main objective of this work was to compare the practical methods of pharmaceutical analysis performed in French and Quebe... | ['Attitude of Health Personnel', 'Drug Prescriptions', 'France', 'Health Facilities', 'Hospitals, University', 'Humans', 'Medication Systems, Hospital', 'Pharmacists', 'Pharmacy Service, Hospital', 'Prospective Studies', 'Quebec', 'Surveys and Questionnaires'] | 30,799,017 | [['F01.100.050', 'N05.300.100'], ['E02.319.307', 'N02.421.668.778.500'], ['Z01.542.286'], ['N02.278'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.442.452.675', 'N04.452.528.473'], ['M01.526.485.780', 'N02.360.780'], ['N02.278.216.500.968.603', 'N02.421.668... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Differential neuronal and glial behavior on flat and micro patterned chitosan films. | Chitosan is a biodegradable natural polysaccharide that has been widely studied for regenerative purposes in the central nervous system. In this study we assessed the in vitro glial and neuronal cells response to chitosan either flat or patterned with grooves in the micrometric range. Chitosan demonstrated to be a good... | ['Animals', 'Axons', 'Brain', 'Central Nervous System', 'Chitosan', 'Humans', 'Neuroglia', 'Neurons'] | 28,750,339 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.186.211'], ['A08.186'], ['D05.750.078.139.500', 'D09.698.211.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.637', 'A11.650'], ['A08.675', 'A11.671']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical deposition improved SERS stability of morphology controlled periodic micro/nanostructured arrays based on colloidal templates. | An effective and inexpensive method is developed to fabricate periodic arrays by sacrificial colloidal monolayer template route by chemical deposition and further physical deposition. By a colloidal template induced precursor solution dipping strategy, different periodic arrays of semi-hollow sphere array, inverse opal... | ['Colloids', 'Gold', 'Magnetic Phenomena', 'Nanostructures', 'Periodicity', 'Physical Phenomena', 'Spectrometry, X-Ray Emission', 'Spectrum Analysis, Raman', 'X-Ray Diffraction'] | 25,356,821 | [['D20.280', 'D26.255.165'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G01.358'], ['J01.637.512'], ['G01.910.645', 'G07.180.562'], ['G01'], ['E05.196.867.800', 'E05.799.830'], ['E05.196.822.860', 'E05.196.867.890'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sciatic nerve fibres in albino rats after atrazine treatment: a morpho-quantitative study. | In this relation the authors present preliminary morpho-quantitative data on the fibres of sciatic nerves of normal albino rats, compared with those of animals treated endoperitoneally with 20 and 40 mg of atrazine. This compound (2 chloro - 4 ethylamino - 6 isopropyl amino-S-triazine) is largely used in agriculture, a... | ['Animals', 'Atrazine', 'Axons', 'Microscopy, Electron', 'Nerve Fibers', 'Rats', 'Rats, Inbred Strains', 'Sciatic Nerve'] | 7,169,298 | [['B01.050'], ['D03.383.931.247'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675.542', 'A11.671.501'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A08.800.800.720.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diffusion and clearance of superparamagnetic iron oxide nanoparticles infused into the rat striatum studied by MRI and histochemical techniques. | The purpose of the present study was to investigate, by MRI and histochemical techniques, the diffusion and clearance abilities of superparamagnetic iron oxide nanoparticles (SPION) coated with dextran (Dextran-SPION) and gold (Au-SPION) following their local infusions into the rat brain. In separate groups of anesthet... | ['Animals', 'Brain Chemistry', 'Corpus Striatum', 'Dextrans', 'Gold', 'Immunohistochemistry', 'Magnetic Resonance Imaging', 'Magnetite Nanoparticles', 'Male', 'Nerve Tissue Proteins', 'Rats', 'Rats, Sprague-Dawley'] | 21,135,466 | [['B01.050'], ['G02.111.150', 'G03.185'], ['A08.186.211.200.885.287.249.487'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Upregulation of IRS-1 expression in Goto-Kakizaki rats following Roux-en-Y gastric bypass surgery: resolution of type 2 diabetes? | Type 2 diabetes mellitus (T2DM) is an endocrine disorder that is rapidly growing in prevalence within China and throughout the world. Roux-en-Y gastric bypass (RYGB) surgery, widely used in the treatment of obesity, has been recognized as an effective and long-term treatment for T2DM in recent years. However, the under... | ['Animals', 'Body Weight', 'Diabetes Mellitus, Type 2', 'Gastric Bypass', 'Glucose Tolerance Test', 'Insulin', 'Insulin Receptor Substrate Proteins', 'Insulin Resistance', 'Liver', 'Organ Specificity', 'Phosphorylation', 'Rats', 'Rats, Wistar', 'Up-Regulation'] | 22,001,674 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intralesional BCG in the treatment of metastatic malignant melanoma. | The therapeutic efficacy of intralesional BCG (Bacillus Calmette-Guerin; one immunizing dose every 2 weeks for a minimum of five treatments) was studied in 19 melanoma patients. Of 15 patients evaluable for response, five experienced significant objective improvement (two complete and three partial remissions). Objecti... | ['Adolescent', 'Adult', 'Aged', 'Cytotoxicity Tests, Immunologic', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Immunotherapy', 'Lymphocytes', 'Male', 'Melanoma', 'Middle Aged', 'Mycobacterium bovis', 'Neoplasm Metastasis', 'Remission, Spontaneous', 'Skin Neoplasms', 'Skin Tests'] | 766,947 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.812.160', 'E05.200.812.160', 'E05.478.594.160', 'E05.940.245'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['C04.557... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise. | We tested the hypothesis that adenosine contributes to augmented skeletal muscle vasodilation during hypoxic exercise. In separate protocols, subjects performed incremental rhythmic forearm exercise (10% and 20% of maximum) during normoxia and normocapnic hypoxia (80% arterial O2 saturation). In protocol 1 (n = 8), sub... | ['Adenosine', 'Adrenergic alpha-Antagonists', 'Adult', 'Aminophylline', 'Blood Flow Velocity', 'Blood Pressure', 'Brachial Artery', 'Exercise', 'Female', 'Forearm', 'Hand Strength', 'Heart Rate', 'Humans', 'Hyperemia', 'Hypoxia', 'Infusions, Intra-Arterial', 'Laser-Doppler Flowmetry', 'Muscle, Skeletal', 'Oxygen', 'Phe... | 19,661,449 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['M01.060.116'], ['D02.092.782.258.368.050', 'D03.633.100.759.758.824.751.075', 'D26.310.048'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A0... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Synthesis of â-D-fructopyranosyl-(2?6)-D-glucopyranose from D-glucose and D-fructose by a thermal treatment. | The synthesis is reported of â-D-fructopyranosyl-(2?6)-D-glucopyranose that had previously been isolated from a fermented plant extract as a new saccharide. A disaccharide was predominately formed from an equal amount of D-glucose and D-fructose under melting conditions at 140 °C for 60 to 90 min. This saccharide was i... | ['Disaccharides', 'Food Industry', 'Fructose', 'Glucose', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Temperature'] | 20,944,409 | [['D09.698.629.305', 'D09.947.750'], ['J01.576.423'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359.448'], ['E05.196.867.519'], ['E05.196.566'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[DHEA and rejuvenating intracrinology? Between reason and magic]. | Slowing down ageing is a goal for a large part of the population. Some mercantile claims hold out bright prospects to DHEA. The effects of this hormone manifest themselves after intracrine conversion. In the skin, sebaceous glands enlarge and seborrhoea increases in post-menopausal women. No other effect is clinically ... | ['Adjuvants, Immunologic', 'Aged', 'Aging', 'Dehydroepiandrosterone', 'Dermatitis, Seborrheic', 'Female', 'Humans', 'Middle Aged', 'Postmenopause', 'Sebaceous Glands'] | 12,233,218 | [['D27.505.696.477.067'], ['M01.060.116.100'], ['G07.345.124'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['C17.800.174.580', 'C17.800.794.230', 'C17.800.815.580', 'C17.800.859.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pattern of calbindin-D28k and calretinin immunoreactivity in the brain of Xenopus laevis during embryonic and larval development. | The present study represents a detailed spatiotemporal analysis of the localization of calbindin-D28k (CB) and calretinin (CR) immunoreactive structures in the brain of Xenopus laevis throughout development, conducted with the aim to correlate the onset of the immunoreactivity with the development of compartmentalizati... | ['Age Factors', 'Animals', 'Anura', 'Brain', 'Calbindin 2', 'Calbindins', 'Choline O-Acetyltransferase', 'Embryo, Nonmammalian', 'Gene Expression Regulation, Developmental', 'Nitric Oxide Synthase', 'S100 Calcium Binding Protein G', 'Tyrosine 3-Monooxygenase', 'Xenopus laevis'] | 22,678,695 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.150.900.090.180'], ['A08.186.211'], ['D12.776.157.125.090.249'], ['D12.776.157.125.090'], ['D08.811.913.050.134.180'], ['A13.350', 'A16.331'], ['G05.308.310'], ['D08.811.682.664.500.772'], ['D12.776.157.125.090.500', 'D12.776.157.125.750.750'], ['D08.811.6... | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Longitudinal study of household smoking ban adoption among Korean Americans. | BACKGROUND: Few longitudinal studies have examined the adoption of bans on smoking in private homes.PURPOSE: This longitudinal study examined: (1) the prevalence of home smoking bans at baseline, (2) the incidence and predictors of new ban implementation by follow-up, and (3) the reasons for banning smoking and the dif... | ['Asian Americans', 'Attitude to Health', 'California', 'Family Health', 'Female', 'Follow-Up Studies', 'Health Surveys', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Smoking', 'Smoking Cessation', 'Smoking Prevention', 'Tobacco Smoke Pollution', 'Tobacco Use Disorder'] | 19,840,699 | [['M01.686.508.200.100', 'M01.686.754.225'], ['F01.100.150', 'N05.300.150'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N01.400.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Identifying optimal reference genes for the normalization of microRNA expression in cucumber under viral stress. | Cucumber green mottle mosaic virus (CGMMV) is an economically important pathogen and causes significant reduction of both yield and quality of cucumber (Cucumis sativus). Currently, there were no satisfied strategies for controlling the disease. A better understanding of microRNA (miRNA) expression related to the regul... | ['Algorithms', 'Cucumis sativus', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Host-Pathogen Interactions', 'MicroRNAs', 'Plant Diseases', 'Plant Leaves', 'Plant Roots', 'Plant Stems', 'Reference Standards', 'Reverse Transcriptase Polymerase Chain Reaction', 'Tobamovirus'] | 29,543,906 | [['G17.035', 'L01.224.050'], ['B01.650.940.800.575.912.250.300.188.666'], ['E05.393.332'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G06.462', 'G16.527.200'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G15.610'], ['A18.024.812'], ['A18.400'], ['A18.024.937'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The influence of uremic sera on the blastic transformation of lymphocytes of healthy subjects, stimulated with non-specific mitogens (PHA, con A, PWM). | The influence of uremic sera on the blastic response of lymphocyte of healthy subjects to nonspecific mitogens (PHA, Con A, PWM) in 3-day culture was investigated. Sera were obtained from 19 patients with renal insufficiency, among them 3 groups were distinguished: terminal renal insufficiency and acute renal insuffici... | ['Adolescent', 'Adult', 'Cells, Cultured', 'Concanavalin A', 'Female', 'Humans', 'Immune Sera', 'Immunosuppressive Agents', 'Lymphocyte Activation', 'Male', 'Phytohemagglutinins', 'Pokeweed Mitogens', 'Stimulation, Chemical', 'Time Factors', 'Uremia'] | 7,416,921 | [['M01.060.057'], ['M01.060.116'], ['A11.251'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['D27.505.696.477.656'], ['E01.370.225.812... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A pilot study of the clinical relevance of the relationship between the serum level of pregnancy-associated plasma protein A and the degree of acute coronary syndrome. | Serum levels of pregnancy-associated plasma protein-A (PAPP-A), high-sensitivity C-reactive protein (hs-CRP) and tumour necrosis factor-alpha (TNF-alpha) were measured in 70 patients with acute coronary syndrome (ACS), comprising 18 with unstable angina (UA), 37 with acute myocardial infarction (AMI) and 15 with stable... | ['Acute Coronary Syndrome', 'Angina, Unstable', 'Biomarkers, Tumor', 'C-Reactive Protein', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pilot Projects', 'Pregnancy', 'Pregnancy-Associated Plasma Protein-A', 'Prognosis', 'Survival Rate', 'Tumor Necrosis Factor-alpha'] | 20,515,576 | [['C14.280.647.124', 'C14.907.585.124'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['D23.101.140'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'],... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Providing pastoral care services in a clinical setting to veterans at-risk of suicide. | The value of enhanced spiritual wellbeing has largely been overlooked as part of suicide prevention efforts in Veterans. The aim of this qualitative study is to examine the clinical pastoral care services provided by VA Chaplains to Veterans at-risk of suicide. This study was conducted using in-depth interviews with fi... | ['Clergy', 'Humans', 'New York', 'Pastoral Care', 'Primary Health Care', 'Qualitative Research', 'Spirituality', 'Suicide', 'Veterans'] | 23,471,771 | [['M01.526.799.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.437', 'Z01.107.567.875.350.530', 'Z01.107.567.875.500.530'], ['F02.784.176.560', 'F02.880.410'], ['N04.590.233.727'], ['H01.770.644.241.850'], ['F02.880.705', 'K01.844.664.500'], ['F01.145.126.980.875', 'I01.880.735.856'], ['M0... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Granulomatous amebic encephalitis in a patient with AIDS: isolation of acanthamoeba sp. Group II from brain tissue and successful treatment with sulfadiazine and fluconazole. | A patient with AIDS, treated with highly active antiretroviral therapy and trimethoprim-sulfamethoxazole, presented with confusion, a hemifield defect, and a mass lesion in the right occipital lobe. A brain biopsy confirmed granulomatous amebic encephalitis (GAE) due to Acanthamoeba castellanii. The patient was treated... | ['Acanthamoeba', 'Acquired Immunodeficiency Syndrome', 'Adult', 'Amebiasis', 'Animals', 'Antibiotic Prophylaxis', 'Antiretroviral Therapy, Highly Active', 'Biopsy', 'Brain', 'Brain Abscess', 'Didanosine', 'Fluconazole', 'Humans', 'Male', 'Saquinavir', 'Sulfadiazine', 'Trimethoprim, Sulfamethoxazole Drug Combination'] | 11,015,431 | [['B01.046.500.100.075.080'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['C01.610.752.049'], ['B01.050'], ['E02.319.162.150', 'E02.319.703.150'], ['E02.319.310.075'], ['E01.370.2... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Unexpected divergence of enzyme function and sequence: "N-acylamino acid racemase" is o-succinylbenzoate synthase. | A protein identified as "N-acylamino acid racemase" from Amycolaptosis sp. is an inefficient enzyme (kcat/Km = 3.7 x 10(2) M-1 s-1). Its sequence is 43% identical to that of an unidentified protein encoded by the Bacillus subtilis genome. Both proteins efficiently catalyze the o-succinylbenzoate synthase reaction in me... | ['Actinobacteria', 'Amino Acid Isomerases', 'Amino Acid Sequence', 'Bacillus subtilis', 'Binding Sites', 'Catalysis', 'Evolution, Molecular', 'Genome, Bacterial', 'Molecular Sequence Data', 'Multigene Family', 'Phosphopyruvate Hydratase', 'Sequence Homology, Amino Acid', 'Structure-Activity Relationship', 'Succinate-Co... | 10,194,342 | [['B03.510.024', 'B03.510.460.400.400.049'], ['D08.811.399.894.200'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['G02.111.570.120'], ['G02.130'], ['G05.045.250', 'G16.07... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of prenatal exposure to ethanol on the development of cerebral cortex: I. Neuronal generation. | Prenatal exposure to ethanol causes profound disruptions in the development of the cerebral cortex. Therefore, the effect of in utero ethanol exposure on the generation of neurons was determined. Pregnant rats were fed a liquid diet in which ethanol constituted 37.5% of the total caloric content (Et) or pair-fed an iso... | ['Animals', 'Autoradiography', 'Cell Division', 'Cell Movement', 'Cell Survival', 'Cerebral Cortex', 'Ethanol', 'Female', 'Gestational Age', 'Neurons', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Thymidine', 'Tritium'] | 3,044,177 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['A08.186.211.200.885.287.500'], ['D02.033.375'], ['G07.345.500.325.235.968', 'G08.686.320'], ['A08.675', 'A11.671'], ['G08.686.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome. | Apert syndrome (AS) is characterized by craniosynostosis (premature fusion of cranial sutures) and severe syndactyly of the hands and feet. Two activating mutations, Ser-252 --> Trp and Pro-253 --> Arg, in fibroblast growth factor receptor 2 (FGFR2) account for nearly all known cases of AS. To elucidate the mechanism b... | ['Acrocephalosyndactylia', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Binding Sites', 'Crystallography, X-Ray', 'Fibroblast Growth Factors', 'Humans', 'Hydrogen Bonding', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Point Mutation', 'Protein Conformation', 'Protein Structure, S... | 11,390,973 | [['C05.116.099.370.894.232.015', 'C05.116.099.370.894.819.100', 'C05.660.207.240.100', 'C05.660.585.800.100', 'C05.660.906.364.100', 'C05.660.906.819.100', 'C16.131.621.207.240.100', 'C16.131.621.585.800.100', 'C16.131.621.906.364.100', 'C16.131.621.906.819.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.4... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cell osmotic water permeability of isolated rabbit proximal convoluted tubules. | Cell osmotic water permeability, Pcos, of the peritubular aspect of the proximal convoluted tubule (PCT) was measured from the time course of cell volume changes subsequent to the sudden imposition of an osmotic gradient, delta Cio, across the cell membrane of PCT that had been dissected and mounted in a chamber. The p... | ['Animals', 'Body Water', 'Cell Membrane', 'Kidney Tubules, Proximal', 'Kinetics', 'Mathematics', 'Osmotic Pressure', 'Permeability', 'Rabbits', 'Sodium Chloride', 'Solutions'] | 6,846,543 | [['B01.050'], ['A12.207.200'], ['A11.284.149'], ['A05.810.453.736.560.570'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['G02.723'], ['B01.050.150.900.649.313.968.700'], ['D01.210.450.150.875', 'D01.857.650'], ['D26.776']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Construction and characterization of Bordetella pertussis mutants lacking the vir-regulated P.69 outer membrane protein. | The Bordetella pertussis P.69 protein is an immunogen with vaccine potential. The role of this protein in pathogenesis is unclear; it has been associated with the toxic adenylate cyclase and adhesion to eukaryotic cells. For further analysis of the role of P.69 in the biology of B. pertussis, we have constructed strain... | ['Adenylyl Cyclases', 'Adhesins, Bacterial', 'Agglutination Tests', 'Animals', 'Bacterial Adhesion', 'Bacterial Outer Membrane Proteins', 'Blotting, Southern', 'Blotting, Western', 'Bordetella pertussis', 'Cell Line', 'Hemagglutinins', 'Humans', 'Kanamycin Resistance', 'Mice', 'Mice, Inbred Strains', 'Mutagenesis, Inse... | 1,787,793 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['B01.050'], ['G06.099.050'], ['D12.776.097.120', 'D12.776.543.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synaptic and neurochemical characterization of parallel pathways to the cytochrome oxidase blobs of primate visual cortex. | The primary visual cortex (V1) of primates is unique in that it is both the recipient of visual signals, arriving via parallel pathways (magnocellular [M], parvocellular [P], and koniocellular [K]) from the thalamus, and the source of several output streams to higher order visual areas. Within this scheme, output compa... | ['Animals', 'Aotus trivirgatus', 'Brain Mapping', 'Electron Transport Complex IV', 'Geniculate Bodies', 'Immunohistochemistry', 'Injections', 'Synapses', 'Visual Cortex', 'Visual Pathways'] | 9,486,823 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.037.092'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['A08.186.211.200.317.826.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of large herbivores on the landscape dynamics of a perennial herb. | BACKGROUND AND AIMS: Models assessing the prospects of plant species at the landscape level often focus primarily on the relationship between species dynamics and landscape structure. However, the short-term prospects of species with slow responses to landscape changes depend on the factors affecting local population d... | ['Animals', 'Computer Simulation', 'Czech Republic', 'Deer', 'Ecosystem', 'Flowers', 'Herbivory', 'Models, Statistical', 'Population Density', 'Scorzonera'] | 22,492,260 | [['B01.050'], ['L01.224.160'], ['Z01.542.248.395'], ['B01.050.150.900.649.313.500.380.373'], ['G16.500.275.157', 'N06.230.124'], ['A18.024.249.500'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['N01.224.600', 'N06.... | ['Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Cost and quality: two sides of the coin in cost containment. | DRGs have increased the effort of healthcare organizations to control costs. But with increased cost containment comes the question of decreased quality of care. Can decreased cost and quality care coexist? Using physician-specified patterns of care in conjunction with cost accounting, cost-effective, quality patient c... | ['Accounting', 'Cost Control', 'Costs and Cost Analysis', 'Diagnosis-Related Groups', 'Financial Management', 'Financial Management, Hospital', 'Quality of Health Care', 'United States'] | 10,311,240 | [['N03.219.463.030'], ['N03.219.151.160'], ['N03.219.151'], ['N03.219.521.710.305.200.080'], ['N03.219.463'], ['N02.278.216.500.875', 'N03.219.463.280', 'N04.452.442.452.180'], ['N04.761', 'N05.715'], ['Z01.107.567.875']] | ['Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Cavernous angiomas of the spinal cord. | Five cases of histologically verified cavernous angiomas of the spinal cord are reported. Acute lower-extremity sensory disturbance was the initial symptom in four patients, and one presented with weakness of the hand. Progressive neurological deficit occurred in all patients, but the clinical course and outcome were e... | ['Adult', 'Female', 'Hemangioma, Cavernous', 'Humans', 'Male', 'Middle Aged', 'Spinal Cord', 'Spinal Cord Neoplasms'] | 3,335,909 | [['M01.060.116'], ['C04.557.645.375.385', 'C14.907.454.385', 'C15.378.463.515.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.854'], ['C04.588.614.250.803', 'C10.228.854.765', 'C10.551.240.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Interplay between synchronization of multivesicular release and recruitment of additional release sites support short-term facilitation at hippocampal mossy fiber to CA3 pyramidal cells synapses. | Synaptic short-term plasticity is a key regulator of neuronal communication and is controlled via various mechanisms. A well established property of mossy fiber to CA3 pyramidal cell synapses is the extensive short-term facilitation during high-frequency bursts. We investigated the mechanisms governing facilitation usi... | ['Animals', 'CA3 Region, Hippocampal', 'Calcium', 'Excitatory Postsynaptic Potentials', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mossy Fibers, Hippocampal', 'Neural Pathways', 'Neuronal Plasticity', 'Pyramidal Cells', 'Recruitment, Neurophysiological', 'Synapses', 'Synaptic Transmission'] | 25,122,902 | [['B01.050'], ['A08.186.211.180.405.174', 'A08.186.211.200.885.287.500.345.174'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of the accessible surface of globular proteins by means of tritium planigraphy. | Results are presented for proteins with known three-dimensional structure (lysozyme, myoglobin, ribonuclease), which show that the probability of label incorporation upon bombardment by "hot" tritium atoms may be quantitatively linked with the surface area of the protein accessible to water molecules. Possible deviatio... | ['Animals', 'Cattle', 'Chickens', 'Female', 'Humans', 'Muramidase', 'Myoglobin', 'Ribonucleases', 'Serum Albumin', 'Surface Properties', 'Tritium', 'Water', 'Whales'] | 8,050,398 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.450.642'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['D08.811.277.352.700'], ['D12.776.034.841', 'D12.776.124.727'], ['G02.860'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.