Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Human genes and pseudogenes for the 7SL RNA component of signal recognition particle. | Of the several hundred 7SL RNA-like sequences that are dispersed in human DNA, no more than four are likely to represent genes for 7SL RNA; the majority are 7SL pseudogenes which appear to result from the reverse flow of genetic information from 7SL RNA back into genomic DNA. We present the sequence of five 7SL pseudog... | ['Base Sequence', 'Cloning, Molecular', 'DNA', 'Gene Amplification', 'Genes', 'Humans', 'Peptides', 'Protein Sorting Signals', 'RNA', 'Transcription, Genetic'] | 6,084,597 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644'], ['D12.644.770', 'G02.111.570.060.670'], ['D13.444.735'], ['G02.111.873', 'G05.297.700']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Photo-inactivation of bacteria in hospital effluent via thiolated iron-doped nanoceria. | Hospital wastewater is a major contributor of disease-causing microbes and the emergence of antibiotic resistant bacteria. In this study, thiolated iron-doped nanoceria was synthesised and tested for killing of microbes from hospital effluent. These particles were designed to inhibit the efflux pumps of the bacteria fo... | ['Bacteria', 'Cerium', 'Coated Materials, Biocompatible', 'Disinfection', 'Foeniculum', 'Green Chemistry Technology', 'Hospitals', 'Iron', 'Light', 'Metal Nanoparticles', 'Microbial Sensitivity Tests', 'Microbial Viability', 'Nanoparticles', 'Phototherapy', 'Reactive Oxygen Species', 'Seeds', 'Sewage', 'Sulfhydryl Comp... | 31,625,530 | [['B03'], ['D01.268.558.362.249', 'D01.552.550.399.249'], ['D25.130.420', 'J01.637.051.130.420'], ['N06.850.780.200.450.850.375'], ['B01.650.940.800.575.912.250.075.333'], ['J01.897.360'], ['N02.278.421'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Pharmacological classification of alpha 1-adrenoceptors mediating contractions of rabbit isolated ear artery: comparison with rat isolated thoracic aorta. | 1. The present study attempted to classify pharmacologically the alpha 1-adrenoceptor subtype(s) present in two isolated, vascular ring preparations, the rabbit ear artery and rat thoracic aorta. 2. In the ear artery, the agonist effects of phenylephrine were antagonized by 5-methyl urapidil (pA2 = 7.90; Schild slope =... | ['Animals', 'Aorta, Thoracic', 'Clonidine', 'Dose-Response Relationship, Drug', 'Ear', 'In Vitro Techniques', 'Male', 'Piperazines', 'Rabbits', 'Rats', 'Receptors, Adrenergic, alpha-1', 'Vasoconstriction'] | 9,117,117 | [['B01.050'], ['A07.015.114.056.372'], ['D03.383.129.308.436.500'], ['G07.690.773.875', 'G07.690.936.500'], ['A01.456.313', 'A09.246'], ['E05.481'], ['D03.383.606'], ['B01.050.150.900.649.313.968.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.670.300.300.300.100', 'D12.776.543.750.695.150.300.300... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a peptide based latex agglutination assay for serotype identification of foot and mouth disease virus. | Out of 200 serum samples collected from cattle (142) and buffaloes (58) of various ages and sexand subjected to latex agglutination test (LAT) using serotype specific peptides (O, A, Asia 1) and also with peptide for non-structural protein 2B (NSP-2B), 114 (70%) samples were positive against FMDV type 'O', 102 (51%) ag... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'Foot-and-Mouth Disease', 'Foot-and-Mouth Disease Virus', 'Latex Fixation Tests', 'Microspheres', 'Molecular Sequence Data', 'Peptides', 'Serotyping', 'Vaccination', 'Viral Nonstructural Proteins'] | 23,923,605 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C01.925.782.687.484', 'C22.380'], ['B04.820.578.750.070.250'], ['E01.370.225.812.735.050.450', 'E05.200.812.735.050.450', 'E05.478.594.760.050.450'], ['E07.565'], ['L01.453.245.667'], ['D12.644'], ['E01.370.225.812.742'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Perceived losses of scientific integrity under the Trump administration: A survey of federal scientists. | President Trump and his administration have been regarded by news outlets and scholars as one of the most hostile administrations towards scientists and their work. However, no study to-date has empirically measured how federal scientists perceive the Trump administration with respect to their scientific work. In 2018,... | ['Federal Government', 'Humans', 'Perception', 'Policy', 'Science', 'Surveys and Questionnaires', 'Trust', 'United States'] | 32,324,823 | [['I01.409.137', 'I01.409.418.625', 'N03.540.348.500', 'N03.540.400.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['I01.655', 'N03.623'], ['H01.770'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['F01.829.401.825'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Biofilm formation and the survival of Salmonella Typhimurium on parsley. | Although several studies provide evidence that the formation of biofilms by human pathogens on plant tissue is possible, to date there is no direct evidence that biofilms enhance the resistance of plant-associated pathogens to disinfectants or biocides. We hypothesized that biofilm formation would enhance the adhesion ... | ['Analysis of Variance', 'Bacterial Adhesion', 'Biofilms', 'Chlorine', 'Colony Count, Microbial', 'Consumer Product Safety', 'Disinfectants', 'Dose-Response Relationship, Drug', 'Food Handling', 'Food Microbiology', 'Mutation', 'Petroselinum', 'Salmonella typhimurium', 'Time Factors'] | 16,616,389 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G06.099.050'], ['A20.593', 'G06.120'], ['D01.268.380.150', 'D01.362.225'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.850.210'], ['D27.505.954.122.425', 'D27.720.274'], ['G07.690.773.875', 'G07.690.936.500'], ['J01.576.423.200'], ['H01.158.273... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Autofluorescence of human skin fibroblasts during growth inhibition and in vitro ageing. | The increase in autofluorescence (AF) of human skin fibroblasts during their in vitro ageing and growth inhibition was investigated by means of flow cytophotometry. The cellular AF of in vitro ageing cultures increased while the relative number of (3H)-thymidine incorporating cells decreased. Therefore, the rate of acc... | ['Adult', 'Aging', 'Cell Separation', 'Cells, Cultured', 'Child, Preschool', 'Female', 'Fibroblasts', 'Flow Cytometry', 'Humans', 'Lipid Peroxides', 'Male', 'Neuronal Ceroid-Lipofuscinoses', 'Skin', 'Skin Physiological Phenomena', 'Vitamin E', 'Werner Syndrome'] | 4,018,588 | [['M01.060.116'], ['G07.345.124'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['M01.060.406.448'], ['A11.329.228'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Low expression of endothelin receptor B (EDNRB) is related to H3K9me3 binding with the EDNRB promoter region and is associated with the clinical T tumor stage in salivary adenoid cystic carcinoma. | OBJECTIVE: To investigate the endothelin receptor B (EDNRB) expression in salivary adenoid cystic carcinoma (ACC) and the mechanism of the regulation of EDNRB expression.STUDY DESIGN: After screening, EDNRB was selected, and the expression was detected using immunohistochemistry in 33 ACC samples (including 6 clinical ... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Carcinoma, Adenoid Cystic', 'Female', 'Histone-Lysine N-Methyltransferase', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Promoter Regions, Genetic', 'Receptor, Endothelin B', 'Salivary Gland Neoplasms', 'Signal Transduction'] | 26,166,030 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['C04.557.470.200.025.220'], ['D08.811.913.555.500.800.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
How molecular interactions affect crystal morphology: the case of haloperidol. | The tableting behaviour of drugs can be dramatically affected by changes in the crystal habit of the drug molecule. Pharmaceutical companies are therefore interested in the morphology prediction as a possible tool to optimise the industrial process. Molecular mechanics calculations embedded in dedicated software togeth... | ['Antipsychotic Agents', 'Crystallization', 'Haloperidol', 'Models, Molecular', 'Powder Diffraction'] | 21,656,519 | [['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.196.300', 'G02.171'], ['D02.522.352.506'], ['E05.599.595'], ['E05.196.309.711']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical Negligence, Systemic Deficiency, or Denial of Emergency Healthcare? Reflections on the European Court of Human Rights Grand Chamber Judgment in Lopes de Sousa Fernandes v. Portugal of 19 December 2017 and Previous Case-law. | On 19 December 2017 the Grand Chamber of the European Court of Human Rights (ECtHR) delivered a judgment in the Lopes de Sousa Fernandes v. Portugal case. The judgment may be described as one of the hard cases dealing with a healthcare context, as it aimed to clarify the scope of positive substantive state obligations ... | ['Fatal Outcome', 'Hospitals', 'Human Rights', 'Humans', 'Jurisprudence', 'Male', 'Malpractice', 'Nasal Polyps', 'Portugal', 'Postoperative Complications', 'Refusal to Treat'] | 31,059,477 | [['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['N02.278.421'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583', 'N03.706.535'], ['I01.880.604.583.524', 'N03.706.535.606'], ['C08.460.572', 'C09.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Bonding and bridging neighborliness: an individual-level study in the context of health. | Although previous research provides a compelling picture of social capital's role in predicting health outcomes, only a modicum of research has tested the more detailed roles of the dimensions of bonding and bridging social capital, with no research focusing exclusively on bonding and bridging neighborliness or ethnici... | ['Adult', 'Cross-Sectional Studies', 'Ethnic Groups', 'Female', 'Friends', 'Health Status', 'Humans', 'Interpersonal Relations', 'Interviews as Topic', 'Male', 'Middle Aged', 'Residence Characteristics', 'Social Support', 'Stress, Psychological', 'United States'] | 19,410,346 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.686.754', 'N01.224.317'], ['M01.252'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Investigation of antisense DNA having C-5 polyamine substituted 2'-deoxyuridine derivative. | Phosphorothioate analogs of oligodeoxyribonucleotide (S-ODN) bearing non-branched polyamine molecule at C-5 position of certain pyrimidine base were synthesized. The synthesis of the modified S-ODNs was accomplished via post-synthetic modification method utilizing C-5 methoxycarbonylmethyl substituted deoxyuridine deri... | ['Anti-HIV Agents', 'Base Sequence', 'Deoxyuridine', 'Genome, Viral', 'HIV-1', 'Nucleic Acid Denaturation', 'Oligodeoxyribonucleotides, Antisense', 'Spermine', 'Temperature', 'Thionucleotides'] | 12,836,297 | [['D27.505.954.122.388.077.088'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.383.742.680.852.300', 'D13.570.230.430', 'D13.570.685.852.300'], ['G05.360.340.358.840'], ['B04.820.650.589.650.350.400'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['D13.150.200.640', 'D13.150.480.640', 'D13.444.308.150... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Molluscicidal properties of Acacia nilotica subspecies tomentosa and astringens II. | A screening programme of plants rich in plant phenolic tannins for molluscicidal activity against the snail species Bulinus truncatus and Biomphalaria pfeifferi is now under way. The spray-dried powders of the pods and stem bark of Acacia nilotica subspp. nilotica, tomentosa and astringens prove to be promising vegetab... | ['Acacia', 'Animals', 'Biomphalaria', 'Bulinus', 'Evaluation Studies as Topic', 'Molluscacides', 'Plant Extracts', 'Snails', 'Sudan', 'Tannins', 'Trees'] | 4,068,077 | [['B01.650.940.800.575.912.250.401.025'], ['B01.050'], ['B01.050.500.644.400.750.185'], ['B01.050.500.644.400.750.323'], ['E05.337', 'N05.715.360.335'], ['D27.720.031.700.596', 'D27.888.723.596'], ['D20.215.784.500', 'D26.667'], ['B01.050.500.644.400.750'], ['Z01.058.290.120.760'], ['D05.750.078.937'], ['B01.650.915']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Atypical presentation of paroxysmal nocturnal hemoglobinuria treated by eculizumab: A case report. | RATIONALE: Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant acquired hematopoietic stem cell disease, which can be revealed by hemolytic anemia, thromboembolism, or bonemarrow failure. Thrombosis can occur at any site, but coronary thrombosis is extremely rare. Controlled trials have demonstrated that eculiz... | ['Aged', 'Antibodies, Monoclonal, Humanized', 'Coronary Thrombosis', 'Coronary Vessels', 'Delayed Diagnosis', 'Fatal Outcome', 'Hemoglobinuria, Paroxysmal', 'Humans', 'Immunologic Factors', 'Male'] | 28,328,837 | [['M01.060.116.100'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['C14.280.647.250.290', 'C14.907.355.830.220', 'C14.907.585.250.290'], ['A07.015.114.269', 'A07.015.908.194'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['E05.318.308.985.550.325', 'N01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins. | Orthodox aquaporins are transmembrane channel proteins that facilitate rapid diffusion of water, while aquaglyceroporins facilitate the diffusion of small uncharged molecules such as glycerol and arsenic trioxide. Aquaglyceroporins play important roles in human physiology, in particular for glycerol metabolism and arse... | ['Aquaglyceroporins', 'Humans', 'Magnetic Resonance Spectroscopy', 'Water'] | 28,914,342 | [['D12.776.157.530.400.500.040.249', 'D12.776.543.550.450.730.040.249', 'D12.776.543.585.400.730.040.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhaled corticosteroids during and after respiratory syncytial virus-bronchiolitis may decrease subsequent asthma. | Respiratory syncytial virus (RSV) bronchiolitis in infancy can lead to bronchial hyper-reactivity or recurrent obstructive bronchitis. The aim of the present study was to determine whether the type of treatment has an influence on respiratory status after RSV bronchiolitis. The study involved 117 infants (mean age 2.6 ... | ['Administration, Inhalation', 'Adrenal Cortex Hormones', 'Asthma', 'Bronchiolitis', 'Bronchodilator Agents', 'Budesonide', 'Disease Management', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Outcome Assessment, Health Care', 'Respiratory Syncytial Virus Infections'] | 10,981,531 | [['E02.319.267.050'], ['D06.472.040'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C01.748.099.135', 'C08.127.446.135', 'C08.381.495.146.135', 'C08.730.099.135'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['D04.210.500.745.745.654.105'], ['N04.590.607'], ['B01.050.150.900.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Nursing students learn about computer-age care. | Part of the problem in computerizing the patient-care process is that caregivers are used to doing things the old-fashioned way, which they may have learned years ago when they got their professional training. One nursing program is including a course on the use of computers in healthcare. | ['Competency-Based Education', 'Computer User Training', 'Education, Nursing', 'Ohio', 'Schools, Nursing'] | 10,114,636 | [['I02.158.210'], ['I02.903.080'], ['I02.358.462'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.540', 'Z01.107.567.875.510.540'], ['I02.783.495.623']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[Clinical studies of SM-4300 in children]. | In vitro experiment with phagocytic and bactericidal activity of human neutrophils, SM-4300 augmented opsonic activity against Pseudomonas aeruginosa. After a single dose of 200 mg/kg body weight SM-4300 to a child with common variable immunodeficiency (CVI), serum IgG concentration/time curve was similar to that after... | ['Anti-Bacterial Agents', 'Bacterial Infections', 'Child, Preschool', 'Drug Evaluation', 'Drug Resistance, Microbial', 'Drug Therapy, Combination', 'Female', 'Humans', 'Immunization, Passive', 'Immunoglobulins', 'Immunologic Deficiency Syndromes', 'Infant', 'Kinetics', 'Male', 'Phagocytosis', 'Pseudomonas aeruginosa'] | 3,935,827 | [['D27.505.954.122.085'], ['C01.150.252'], ['M01.060.406.448'], ['E05.290.625', 'E05.337.425'], ['G06.225', 'G07.690.773.984.269'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['C... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Draft genome sequence of the human pathogen Streptomyces somaliensis, a significant cause of actinomycetoma. | We report the draft genome sequence of the human pathogen Streptomyces somaliensis (DSM 40738), a pathogen within a genus of largely saprophytic organisms. S. somaliensis causes severe and debilitating deep tissue and bone infections. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number AJJM0... | ['Actinomycetales Infections', 'Foot Diseases', 'Genome, Bacterial', 'Humans', 'Male', 'Molecular Sequence Data', 'Mycetoma', 'Sequence Analysis, DNA', 'Streptomyces', 'Young Adult'] | 22,689,234 | [['C01.150.252.410.040'], ['C05.360', 'C17.800.321'], ['G05.360.340.358.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['C01.150.252.410.040.692.500', 'C01.150.252.819.557', 'C01.150.703.302.500', 'C01.800.200.500', 'C01.800.720.557', 'C17.800.838.208.557', 'C17.800.838.765.557'], ['E05.39... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Parameter optimization of the QUAL2K model for a multiple-reach river using an influence coefficient algorithm. | An influence coefficient algorithm and a genetic algorithm (GA) were introduced to develop an automatic calibration model for QUAL2K, the latest version of the QUAL2E river and stream water-quality model. The influence coefficient algorithm was used for the parameter optimization in unsteady state, open channel flow. T... | ['Algorithms', 'Calibration', 'Chlorophyll', 'Chlorophyll A', 'Environmental Monitoring', 'Models, Theoretical', 'Oxygen', 'Republic of Korea', 'Rivers', 'Water Pollution', 'Water Supply'] | 20,163,823 | [['G17.035', 'L01.224.050'], ['E05.978.155'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.599'], ['D01.268.185.550', 'D01.362.670'], ['Z01.252.474.557.750'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Genetic and phenotypic characterization of Haemophilus influenzae type b isolated from children with meningitis and their family members in Vietnam. | To investigate Haemophilus influenzae type b (Hib) infection in Vietnamese children under the age of 5 years, cerebrospinal fluid (CSF) samples from patients with meningitis were screened for Hib, and isolates were subjected to evaluation of susceptibility to 12 antibiotics, biotyping, and genotyping with pulsed-field ... | ['Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Cerebrospinal Fluid', 'Child', 'Child, Preschool', 'Cluster Analysis', 'Disease Reservoirs', 'Dose-Response Relationship, Drug', 'Drug Resistance, Bacterial', 'Electrophoresis, Gel, Pulsed-Field', 'Female', 'Haemophilus influenzae type b', 'Humans', 'Infant', 'Male', 'M... | 16,632,911 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['A12.207.270.210'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N06.850.520.203.250'], ['G07.690.773.875', 'G07.690.936.500'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['E05.196.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Mean-based neural coding of voices. | The social significance of recognizing the person who talks to us is obvious, but the neural mechanisms that mediate talker identification are unclear. Regions along the bilateral superior temporal sulcus (STS) and the inferior frontal cortex (IFC) of the human brain are selective for voices, and they are sensitive to ... | ['Brain Mapping', 'Female', 'Humans', 'Male', 'Nerve Net', 'Pattern Recognition, Physiological', 'Recognition, Psychology', 'Speech Perception', 'Temporal Lobe', 'Voice', 'Young Adult'] | 23,664,949 | [['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.511'], ['F02.463.593.524'], ['F02.463.425.540.706'], ['F02.463.593.071.875', 'G07.888.125.875'], ['A08.186.211.200.885.287.500.863'], ['G09.772.925'], ['M01.060.116.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stem cells - 13 years since their isolation, is there any proven benefit to the patient? | Stem cells are seen as the 'magic bullet'; while this may be true, their efficacy and safety in patients has not yet been established unequivocally. This article summarises the different types of stem cells and gives an overview of their advantages and disadvantages, their use, and potential uses in the patient setting... | ['Clinical Trials as Topic', 'Humans', 'Stem Cell Research', 'Stem Cell Transplantation'] | 22,273,021 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.242.950', 'H01.770.644.145.512'], ['E02.095.147.500.500', 'E04.936.225.687']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Protein turnover in acid maltase deficiency before and after treatment with a high protein diet. | A patient with acid maltase deficiency was treated with a high protein diet for 7 months. Protein turnover expressed in terms of lean body mass was shown to be increased in this patient before the diet but was markedly reduced following the diet. The patient improved clinically whilst on the diet both subjectively and ... | ['Adult', 'Dietary Proteins', 'Glucan 1,4-alpha-Glucosidase', 'Glucose Tolerance Test', 'Glucosidases', 'Glycogen Storage Disease', 'Glycogen Storage Disease Type II', 'Humans', 'Leucine', 'Male', 'Muscle Proteins', 'alpha-Glucosidases'] | 3,108,456 | [['M01.060.116'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['D08.811.277.450.420.375'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['D08.811.277.450.420'], ['C16.320.565.202.449', 'C18.452.648.202.449'], ['C10.228.140.163.100.435.340', 'C16.320.565.189.435.340', 'C16.320.565.202.44... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Hic, a novel surface protein of Streptococcus pneumoniae that interferes with complement function. | The important human pathogen Streptococcus pneumoniae was found to absorb factor H, an inhibitor of complement, from human plasma. We identified the gene encoding a novel surface protein, factor H-binding inhibitor of complement (Hic), in the pspC locus of type 3 pneumococci. Unlike PspC proteins in other serotypes, Hi... | ['Alleles', 'Amino Acid Sequence', 'Bacterial Proteins', 'Carrier Proteins', 'Complement Factor H', 'Humans', 'Kinetics', 'Molecular Sequence Data', 'Protein Binding', 'Streptococcus pneumoniae', 'Surface Plasmon Resonance', 'Surface Properties'] | 10,967,103 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D12.776.157'], ['D12.776.124.486.274.920.325.200', 'D12.776.124.790.223.200', 'D12.776.377.715.182.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['G02.111.679', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Age-associated time delays in the treatment of acute myocardial infarction with primary percutaneous transluminal coronary angioplasty. | Multiple studies have shown that age is a significant factor associated with suboptimal treatment for acute myocardial infarction (AMI). We performed a retrospective pilot study using a chart review of patients who presented with AMI who were subsequently treated with percutaneous transluminal coronary angioplasty (PTC... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Cohort Studies', 'Humans', 'Middle Aged', 'Myocardial Infarction', 'New York', 'Pilot Projects', 'Retrospective Studies', 'Time Factors'] | 15,672,332 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E05.318.372.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of nano-hydroxyapatite coating on the osteoinductivity of porous biphasic calcium phosphate ceramics. | BACKGROUND: Porous biphasic calcium phosphate (BCP) ceramics exhibit good biocompatibility and bone conduction but are not inherently osteoinductive. To overcome this disadvantage, we coated conventional porous BCP ceramics with nano-hydroxyapatite (nHA). nHA was chosen as a coating material due to its high osteoinduct... | ['Animals', 'Biomarkers', 'Bone Regeneration', 'Cell Adhesion', 'Cell Differentiation', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Ceramics', 'Coated Materials, Biocompatible', 'Durapatite', 'Hydroxyapatites', 'Materials Testing', 'Mesenchymal Stem Cells', 'Nanoparticles', 'Osteogenesis', 'Porosity', 'R... | 24,690,170 | [['B01.050'], ['D23.101'], ['G11.427.213.140', 'G16.762.150.150'], ['G04.022'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['J01.637.153'], ['D25.130.420', 'J01.637.051.130.420'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Decreased expression of histone deacetylase 10 predicts poor prognosis of gastric cancer patients. | Aberrant expression of histone deacetylase (HDACs) was associated with carcinogenesis and progression of various tumors. However, the association of HDAC10 with clinical outcomes in gastric cancer patients is unclear. Thus, the objective of the current study was to evaluate the association of expression level of HDAC10... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Chi-Square Distribution', 'Down-Regulation', 'Female', 'Histone Deacetylases', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Grading', 'Neoplasm Invasiveness', 'Neo... | 25,337,229 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D08.811.277.087.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.60... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional evidence for adenosine A2 receptor regulation of phosphatidylcholine secretion in cultured type II pneumocytes. | We examined the effects of P1 purinoceptor agonists on secretion of phosphatidylcholine in primary cultures of rat type II pneumocytes. Adenosine and its nonmetabolizable analogs, 5'-N-ethylcarboxyamidoadenosine (NECA), N6-phenylisopropyladenosine (PIA) and 2-chloroadenosine, increased secretion, and this effect was de... | ['2-Chloroadenosine', 'Adenosine', "Adenosine-5'-(N-ethylcarboxamide)", 'Animals', 'Cyclic AMP', 'Male', 'Phenylisopropyladenosine', 'Phosphatidylcholines', 'Pulmonary Alveoli', 'Rats', 'Rats, Inbred Strains', 'Receptors, Purinergic', 'Terbutaline', 'Theophylline'] | 3,037,072 | [['D03.633.100.759.590.138.300', 'D13.570.583.138.300', 'D13.570.800.096.300'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.590.138.025', 'D13.570.583.138.025', 'D13.570.800.096.250'], ['B01.050'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.69... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acetylcholine inhibits nitric oxide (NO) synthesis in the gastropod nervous system. | Acetylcholine (ACh) is one of the main signals regulating nitric oxide synthase (NOS) expression and nitric oxide (NO) biosynthesis in mammals. However, few comparative studies have been performed on the role of ACh on NOS activity in non-mammalian animals. We have therefore studied the cholinergic control of NOS in th... | ['Acetylcholine', 'Animals', 'Gene Expression Profiling', 'Helix, Snails', 'Muscle Contraction', 'Nerve Net', 'Nervous System', 'Nicotine', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitrites', 'Tubocurarine'] | 19,255,787 | [['D02.092.211.111'], ['B01.050'], ['E05.393.332'], ['B01.050.500.644.400.750.450'], ['G11.427.494'], ['A08.511'], ['A08'], ['D03.132.760.570', 'D03.383.725.518'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D08.811.682.664.500.772'], ['D01.248.497.158.635', 'D01.625.600.600', 'D02.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model. | Despite the tremendous biological activity of polysaccharides from the mushroom Dictyophora indusiata, its role in the restoration of gut microbiota has not yet been explored. The present study aimed to investigate whether D. indusiata polysaccharide (DIP) could modulate the recovery of gut microbiota composition and i... | ['Agaricales', 'Animals', 'Clindamycin', 'Cytokines', 'Disease Models, Animal', 'Dysbiosis', 'Endotoxins', 'Feces', 'Fungal Polysaccharides', 'Gastrointestinal Microbiome', 'Inflammation Mediators', 'Intestinal Diseases', 'Intestinal Mucosa', 'Intestines', 'Male', 'Metronidazole', 'Mice, Inbred BALB C', 'Permeability',... | 30,065,236 | [['B01.300.179.100'], ['B01.050'], ['D03.383.773.532.500.125', 'D09.408.471.500.125'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.308'], ['D23.946.123.329'], ['A12.459'], ['D09.698.357', 'D23.050.202.283'], ['G06.591.375', 'G16.500.275.157.049.100.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Convergent Ditopic Receptors Enhance Anion Binding upon Alkali Metal Complexation for Catalyzing the Ritter Reaction. | A supramolecular approach to catalyzing the Ritter reaction by utilizing enhanced anion-binding affinity in the presence of alkali metal cations was developed with ditopic hydrogen-bonded amide macrocycles. With prebound cations in the macrocycle, particularly Li+ ion, their metal complexes exhibit greatly enhanced cat... | ['Amides', 'Catalysis', 'Hydrogen Bonding', 'Macrocyclic Compounds', 'Metals, Alkali'] | 30,638,017 | [['D02.065'], ['G02.130'], ['G02.282'], ['D04.345'], ['D01.268.549', 'D01.552.528']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of antimicrobial photodynamic therapy in open flap debridement in the treatment of peri-implantitis: A randomized controlled trial. | BACKGROUND: To evaluate the effects of single application of antimicrobial photodynamic therapy (aPDT) as an adjunct to open flap debridement (OFD) and OFD alone in patients with peri-implantitis (PI).MATERIALS AND METHODS: Twenty four patients with PI were divided into 2 groups receiving aPDT with OFD and OFD alone re... | ['Aged', 'Combined Modality Therapy', 'Debridement', 'Dental Plaque Index', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peri-Implantitis', 'Periodontal Index', 'Photochemotherapy', 'Photosensitizing Agents'] | 29,738,817 | [['M01.060.116.100'], ['E02.186'], ['E04.176'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.714.282'], ['E05.318.308.980.438.300.725', 'E06.208.720... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats. | OBJECTIVE: Hypothalamic inflammation and glial fibrillary acidic protein (GFAP) overexpression in astrocytes are well described in obese animals, as are some cognitive and memory deficits. As the hippocampus plays important roles in the consolidation of information, this investigation aimed to observe the memory functi... | ['Adipose Tissue', 'Animals', 'Astrocytes', 'Diet, High-Fat', 'Glial Fibrillary Acidic Protein', 'Hippocampus', 'Immunohistochemistry', 'Male', 'Memory Disorders', 'Obesity', 'Rats, Wistar', 'Reference Values', 'Time Factors'] | 31,553,389 | [['A10.165.114'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['G07.203.650.240.267'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Chylothorax associated with right-sided heart failure in five cats. | Chylothorax associated with right-sided congestive heart failure was diagnosed in 5 cats. One cat had restrictive pericardial disease, with mild pericardial effusion, and a heart-base chemodectoma. Two other cats had congestive cardiac disease (tetralogy of Fallot and tricuspid regurgitation in 1 cat, and endocardial c... | ['Animals', 'Cat Diseases', 'Cats', 'Chylothorax', 'Echocardiography', 'Female', 'Heart Failure', 'Male', 'Pericardial Effusion', 'Pericardiectomy', 'Pleural Effusion', 'Tetralogy of Fallot', 'Tricuspid Valve Insufficiency'] | 8,125,826 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C08.528.142'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.434'], ['C14.280.695'], ['E04.100.376.735', 'E04.928.220.605'], ['C08.528.652'], ['C14.240.400.849', 'C14.280.400.849', 'C16.131.240.400.849'], ['... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of rigid and flexible fibreoptic sigmoidoscopy with double contrast barium enemas. | One hundred consecutive new patients attending a general surgical and gastrointestinal outpatient clinic had a flexible fibreoptic sigmoidoscopic examination before a double contrast barium enema. Colonic lesions were found in 45 patients and flexible sigmoidoscopy was superior to barium enemas in diagnosing lesions in... | ['Adult', 'Barium Sulfate', 'Colonic Diseases', 'Enema', 'Female', 'Fiber Optic Technology', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Sigmoid Diseases', 'Sigmoidoscopy'] | 7,104,610 | [['M01.060.116'], ['D01.103.075', 'D01.875.800.800.850.075'], ['C06.405.469.158'], ['E02.319.347'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['C06.405.469.158.850'], ['E01.370.372.250.250.200.700', 'E01.370.388.250.250.250.160.800', 'E04.210.240.250... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Xanthones Content in Swertia multicaulis | The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S. multicaulis determined by HPLC reaches almost 13 g of xanthones per 1 kg of dry matter. The identification of xanthones in S. mu... | ['Chromatography, Liquid', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Phytochemicals', 'Plant Extracts', 'Secondary Metabolism', 'Swertia', 'Tandem Mass Spectrometry', 'Xanthones'] | 29,751,500 | [['E05.196.181.400'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D23.704'], ['D20.215.784.500', 'D26.667'], ['G03.493.875'], ['B01.650.940.800.575.912.250.456.750.594'], ['E05.196.566.880'], ['D03.633.300.953.852']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel "hitch-and-ride" deep biliary cannulation method during rendezvous endoscopic ultrasound-guided ERCP technique. | Background and study aim Endoscopic ultrasound-guided rendezvous (EUS-RV) is increasingly reported as a treatment option after failed endoscopic retrograde cholangiopancreatography. We developed a novel "hitch-and-ride" catheter for biliary cannulation to reduce the risk of guidewire loss during EUS-RV. Patients and me... | ['Aged', 'Aged, 80 and over', 'Bile Ducts', 'Catheterization', 'Catheters', 'Cholangiopancreatography, Endoscopic Retrograde', 'Endosonography', 'Female', 'Humans', 'Male', 'Retrospective Studies', 'Ultrasonography, Interventional'] | 28,732,390 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.159.183'], ['E02.148', 'E05.157'], ['E07.132'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['E01.370.350.850.280'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Asbestos-related disease associated with exposure to asbestiform tremolite. | Tremolite is nearly ubiquitous and represents the most common amphibole fiber in the lungs of urbanites. Tremolite asbestos is not mined or used commercially but is a frequent contaminant of chrysotile asbestos, vermiculite, and talc. Therefore, individuals exposed to these materials or to end-products containing these... | ['Adult', 'Aged', 'Asbestos', 'Asbestos, Amphibole', 'Asbestosis', 'Environmental Exposure', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Mesothelioma', 'Middle Aged', 'Occupational Exposure'] | 7,892,832 | [['M01.060.116'], ['M01.060.116.100'], ['D01.578.725.050', 'D01.837.725.700.760.070'], ['D01.578.725.050.050', 'D01.837.725.700.760.070.050'], ['C08.381.483.581.125', 'C08.381.520.702.125', 'C24.800.127'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dynamic gene expression in the song system of zebra finches during the song learning period. | The brain circuitry that controls song learning and production undergoes marked changes in morphology and connectivity during the song learning period in juvenile zebra finches, in parallel to the acquisition, practice and refinement of song. Yet, the genetic programs and timing of regulatory change that establish the ... | ['Animals', 'Avian Proteins', 'Brain', 'Cell Count', 'Critical Period, Psychological', 'Finches', 'Gene Expression Regulation, Developmental', 'In Situ Hybridization', 'Learning', 'Male', 'Vocalization, Animal'] | 25,787,707 | [['B01.050'], ['D12.776.095'], ['A08.186.211'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['F02.463.425.209'], ['B01.050.150.900.248.620.750.250'], ['G05.308.310'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Investigation of tumor related anemia in 10,218 patients with cancer in the digestive system]. | OBJECTIVE: To study the prevalence of tumor related anemia in patients with cancer in the digestive system.METHODS: A total of of 10 218 inpatients were diagnosed with cancer in the digestive system at the Peking Union Hospital from January 2000 to June 2009, which included esophageal cancer(n=1118), gastric cancer(n=2... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anemia', 'China', 'Digestive System Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Young Adult'] | 21,614,687 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.071'], ['Z01.252.474.164'], ['C04.588.274', 'C06.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
On the role of calcium in the acute release of tissue-type plasminogen activator and von Willebrand factor from the rat perfused hindleg region. | The involvement of calcium in the release of tissue-type plasminogen activator (t-PA) and von Willebrand Factor (vWF) from vascular endothelial cells was studied ex vivo using a rat hindleg perfusion system. By adding either platelet-activating factor or bradykinin to the perfusing Tyrode solution, a rapid release of t... | ['3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester', 'Animals', 'Calcimycin', 'Calcium', 'Calcium Channel Blockers', 'Calmodulin', 'Endothelium, Vascular', 'Enzyme-Linked Immunosorbent Assay', 'Hindlimb', 'Male', 'Perfusion', 'Rats', 'Rats, Inbred Strains', 'Spect... | 1,724,576 | [['D03.383.725.203.600', 'D03.383.725.547.900'], ['B01.050'], ['D03.633.100.221.173'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['A07.015.700.500', 'A10.272.491... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of global gene expression in brain by TMP21. | TMP21, a type I transmembrane protein of thep24 protein family, mediates protein trafficking and maturation. Dysregulation of TMP21 is implicated in the pathogenesis of Alzheimer's disease (AD). However, underlying mechanisms remain elusive. To reveal the function of TMP21 in the brain and the pathogenic role of TMP21 ... | ['Animals', 'Brain', 'Epistasis, Genetic', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Gene Ontology', 'Gene Regulatory Networks', 'Hippocampus', 'Membrane Proteins', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Transcription, Genetic'] | 31,036,051 | [['B01.050'], ['A08.186.211'], ['G05.308.207'], ['E05.393.332'], ['G05.308'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['G05.360.080.689.360'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.77... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
A consensus-guided approach yields a heat-stable alkane-producing enzyme and identifies residues promoting thermostability. | Aldehyde-deformylating oxygenase (ADO) is an essential enzyme for production of long-chain alkanes as drop-in biofuels, which are compatible with existing fuel systems. The most active ADOs are present in mesophilic cyanobacteria, especially Nostoc punctiforme Given the potential applications of thermostable enzymes in... | ['Aldehydes', 'Alkanes', 'Biofuels', 'Cyanobacteria', 'Enzyme Stability', 'Escherichia coli', 'Genes, Bacterial', 'Hot Springs', 'Hot Temperature', 'Metagenome', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Nostoc', 'Oxygenases', 'Protein Conformation'] | 29,632,075 | [['D02.047'], ['D02.455.326.146'], ['D20.147', 'N06.230.132.644.124'], ['B03.280', 'B03.440.475.100'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G01.311.355.750.500', 'G16.500.275.2... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characteristics of patients with gaze-evoked tinnitus. | OBJECTIVE: The authors describe symptoms and population characteristics in subjects who can modulate the loudness and/or pitch of their tinnitus by eye movements.STUDY DESIGN: Data were obtained by questionnaire.SETTING: The study was conducted at a university center and a tertiary care center.PATIENTS: Respondents had... | ['Adult', 'Aged', 'Cerebellopontine Angle', 'Cochlear Nerve', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Middle Aged', 'Postoperative Period', 'Saccades', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Tinnitus', 'Tomography, Emission-Computed'] | 11,568,674 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211.132.810.428.200.462'], ['A08.800.800.120.910.120'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.750', 'N02.421.585.753.750'], ['G14.350.500'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.50... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anti-tumor promoting activity of canventol and its synthetic analogs through inhibition of protein isoprenylation. | Canventol, a synthetic compound, is a new inhibitor of tumor promotion on mouse skin by okadaic acid. We previously reported that canventol acts by inhibiting both protein isoprenylation and tumor necrosis factor-alpha (TNF-alpha) release. In this study we examined the potencies of 10 newly synthesized canventol analog... | ['3T3 Cells', 'Alkyl and Aryl Transferases', 'Animals', 'Anticarcinogenic Agents', 'Carcinogens', 'Cyclohexanols', 'Enzyme Inhibitors', 'Female', 'Lipid Metabolism', 'Mevalonic Acid', 'Mice', 'Mice, Inbred Strains', 'Okadaic Acid', 'Protein Prenylation', 'Skin Neoplasms', 'Sterols', 'Transferases', 'Ubiquinone'] | 8,878,447 | [['A11.251.210.100', 'A11.329.228.100'], ['D08.811.913.225'], ['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D27.888.569.100'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['D27.505.519.389'], ['G03.458'], ['D02.241.511.579'], ['B01.050.150.900.649.313.9... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient phloem transport significantly remobilizes cadmium from old to young organs in a hyperaccumulator Sedum alfredii. | Our knowledge of cadmium (Cd) in hyperaccumulators mainly concerns root uptake, xylem translocation and foliar detoxification, while little attention has been paid to the role of phloem remobilization. We investigated Cd distribution in different organs of the hyperaccumulating ecotype (HE) of Sedum alfredii and compar... | ['Biological Transport', 'Cadmium', 'Phloem', 'Plant Structures', 'Sedum'] | 30,453,235 | [['G03.143'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['A18.450.250'], ['A18'], ['B01.650.940.800.575.912.250.859.937.249.750']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Numerical model of deep venous thrombosis detection using venous occlusion strain gauge plethysmography. | Strain gauge plethysmography (SGP) is a non-invasive method used in the detection of deep venous thrombosis (DVT). The technique is based on the measurement of calf volume changes in response to venous occlusion by a thigh cuff, the volume changes reflecting the rates of arterial inflow and venous outflow. A numerical ... | ['Humans', 'Leg', 'Models, Cardiovascular', 'Plethysmography', 'Regional Blood Flow', 'Venous Thrombosis'] | 10,912,353 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['E05.599.395.161'], ['E01.370.370.610'], ['G09.330.100.780'], ['C14.907.355.830.925']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnostic validity of flow cytometry vs manual counting of polymorphonuclear leukocytes in spontaneous bacterial peritonitis. | BACKGROUND: Spontaneous bacterial peritonitis (SBP) is frequently occurring infection among patients with liver cirrhosis, defined by polymorphonuclear (PMN) leukocytic count ?250 cell/mm3 with or without a positive ascitic fluid (AF) bacterial culture. So, this study aimed to investigate the diagnostic value of flow c... | ['Aged', 'Antigens, CD', 'Bacterial Infections', 'Cross-Sectional Studies', 'Egypt', 'Female', 'Flow Cytometry', 'Humans', 'Leukocyte Count', 'Male', 'Middle Aged', 'Neutrophils', 'Peritonitis', 'ROC Curve', 'Sensitivity and Specificity'] | 29,383,775 | [['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['C01.150.252'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.266.317'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Dysynchiria is not a common feature of neuropathic pain. | Patients with chronic neuropathic pain (non-CRPS) and brush-evoked allodynia watched a reflected image of their corresponding but opposite skin region being brushed in a mirror. Unlike complex regional pain syndrome Type 1, this process did not evoke any sensation at the affected area ('dysynchiria'). We conclude that ... | ['Chronic Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuralgia', 'Nociceptors', 'Pain Threshold', 'Paresthesia'] | 17,446,100 | [['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.668.829.600', 'C23.888.592.612.664'], ['A08.675.650.915.875', 'A08.800.950.875', 'A11.671.650.915.875'], ['F02.463.593.710.560', 'F02.830.816.444.700', 'G11.561.790.444.700'], ['C10.597.751.791.875', 'C23.888.592.763.770.8... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Testing evidence routine practice: Using an implementation framework to embed a clinically proven asthma service in Australian community pharmacy. | INTRODUCTION: Community pharmacists are well placed and evidence clearly demonstrates that they can be suitably trained to deliver professional services that improve the management of asthma patients in clinical, economic and humanistic terms. However the gap between this evidence and practice reality remains wide. In ... | ['Asthma', 'Australia', 'Community Pharmacy Services', 'Humans', 'Nebulizers and Vaporizers', 'Pharmacies', 'Program Evaluation'] | 28,583,300 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['Z01.639.100', 'Z01.678.100.373'], ['N02.421.143.221', 'N02.421.668.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.605'], ['N02.278.678'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']] | ['Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Exploration of the virome of the European brown shrimp (Crangon crangon | Crangon crangon is economically a very important species. Recently, promising culture attempts have been made, but a major problem is the uncontrollable mortality during the grow-out phase. As of yet, the life cycle of C. crangon is not closed in captivity so wild-caught individuals are used for further rearing. Theref... | ['Animals', 'Aquaculture', 'Crangonidae', 'DNA Viruses', 'Penaeidae'] | 32,391,748 | [['B01.050'], ['J01.040.168'], ['B01.050.500.131.365.190.150'], ['B04.280'], ['B01.050.500.131.365.190.660']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Uncovering toxicological complexity by multi-dimensional screenings in microsegmented flow: modulation of antibiotic interference by nanoparticles. | The technique of microsegmented flow was applied for the generation of two- and higher dimensional concentration spaces for the screening of toxic effects of selected substances on the bacterium Escherichia coli at the nanolitre scale. Up to about 5000 distinct experiments with different combinations of effector-concen... | ['Ampicillin', 'Anti-Bacterial Agents', 'Chloramphenicol', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Escherichia coli', 'Evaluation Studies as Topic', 'Metal Nanoparticles', 'Microfluidics', 'Reproducibility of Results', 'Silver', 'Toxicity Tests'] | 22,080,187 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D27.505.954.122.085'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968.477'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Does aberrant expression of cyclooxygenase-2 and prostaglandin-E2 receptor genes lead to abortion in Chlamydia trachomatis-infected women. | OBJECTIVE: The aim of the study was to characterize the expression of cyclooxygenase-2 (COX-2) and prostaglandin-E2 (PGE2) genes in spontaneously aborted tissues from women infected with Chlamydia trachomatis.METHODS: A total of 135 spontaneous aborters (Group I) and 45 induced aborters (controls; Group II) attending O... | ['Abortion, Spontaneous', 'Adult', 'Case-Control Studies', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Cyclooxygenase 2', 'Dinoprostone', 'Female', 'Humans', 'India', 'Pilot Projects', 'Pregnancy', 'Prevalence', 'Receptors, Prostaglandin E', 'Young Adult'] | 25,812,673 | [['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.190.750'], ['D08.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Long term follow-up after finger replantation. | The aim of this retrospective study was to assess objective and subjective aspects of the long-term results of finger replantations and revascularisations. Forty patients with 59 successfully replanted or revascularised fingers, who had a mean age of 38 years, were followed-up over an average of 3.5 years. The assessme... | ['Cold Temperature', 'Fingers', 'Follow-Up Studies', 'Humans', 'Range of Motion, Articular', 'Recovery of Function', 'Replantation', 'Retrospective Studies', 'Sensation', 'Treatment Outcome'] | 18,332,022 | [['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['A01.378.800.667.430'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600.700... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transient Peripheral Immune Activation follows Elective Sigmoidoscopy or Circumcision in a Cohort Study of MSM at Risk of HIV Infection. | BACKGROUND: Rectal and genital sampling in HIV prevention trials permits assessments at the site of HIV entry. Yet the safety and acceptability of circumcision and sigmoidoscopy (and associated abstinence recommendations) are unknown in uncircumcised men who have sex with men (MSM) at high risk of HIV infection.METHODS... | ['Adult', 'CD4-Positive T-Lymphocytes', 'Circumcision, Male', 'Cohort Studies', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Immunity, Cellular', 'Male', 'Peru', 'Risk Factors', 'Sexual Behavior', 'Sigmoidoscopy', 'Young Adult'] | 27,536,938 | [['M01.060.116'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['E02.218.085.170', 'E04.085.170', 'E04.950.774.860.226'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C0... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
SMILE, a new orphan nuclear receptor SHP-interacting protein, regulates SHP-repressed estrogen receptor transactivation. | SHP (small heterodimer partner) is a well-known NR (nuclear receptor) co-regulator. In the present study, we have identified a new SHP-interacting protein, termed SMILE (SHP-interacting leucine zipper protein), which was previously designated as ZF (Zhangfei) via a yeast two-hybrid system. We have determined that the S... | ['Animals', 'Basic-Leucine Zipper Transcription Factors', 'Cell Line', 'E2F1 Transcription Factor', 'Humans', 'Leucine Zippers', 'Mice', 'Protein Isoforms', 'RNA, Small Interfering', 'Receptors, Cytoplasmic and Nuclear', 'Receptors, Estrogen', 'Tissue Distribution', 'Transcription, Genetic', 'Transcriptional Activation... | 18,657,049 | [['B01.050'], ['D12.776.260.108', 'D12.776.930.127'], ['A11.251.210'], ['D12.644.360.024.328.049', 'D12.776.157.057.158.049', 'D12.776.476.024.420.049', 'D12.776.660.769.049', 'D12.776.930.211.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820.709.275.500.520'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl. | Polychlorinated biphenyls (PCBs) may be metabolically activated to electrophiles, which bind to proteins and nucleic acids. One activation scheme involves the formation of reactive arene oxide intermediates during cytochrome P450-catalyzed hydroxylation. We propose a second activation pathway whereby PCB catechol and h... | ['Animals', 'Biphenyl Compounds', 'Catechols', 'Hydroquinones', 'Kinetics', 'Male', 'Microsomes, Liver', 'Polychlorinated Biphenyls', 'Rats', 'Rats, Sprague-Dawley'] | 8,924,585 | [['B01.050'], ['D02.455.426.559.389.185'], ['D02.455.426.559.389.657.166'], ['D02.455.426.559.389.657.393'], ['G01.374.661', 'G02.111.490'], ['A11.284.835.540.541'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impaired lymphoid chemokine-mediated migration due to a block on the chemokine receptor switch in human cytomegalovirus-infected dendritic cells. | Dendritic cell (DC) migration from the site of infection to the site of T-cell priming is a crucial event in the generation of antiviral T-cell responses. Here we present to our knowledge the first functional evidence that human cytomegalovirus (HCMV) blocks the migration of infected monocyte-derived DCs toward lymphoi... | ['Chemokine CCL19', 'Chemokine CCL21', 'Chemokines, CC', 'Chemotaxis', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Dendritic Cells', 'Humans', 'NF-kappa B', 'Receptors, CCR7', 'Receptors, Chemokine'] | 14,990,723 | [['D12.644.276.374.200.110.870', 'D12.644.276.374.200.600.870', 'D12.776.467.374.200.110.870', 'D12.776.467.374.200.600.870', 'D23.125.300.110.870', 'D23.125.300.600.870', 'D23.469.200.110.870', 'D23.469.200.600.870', 'D23.529.374.200.110.870', 'D23.529.374.200.600.870'], ['D12.644.276.374.200.110.890', 'D12.776.467.37... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Design of an adjustable simulated lung]. | We designed an adjustable simulated lung for clinical use. Depending on the feature of adjustable resistance and compliance, the device could simulate various pathological changes of lung, such as obstructive diseases and restrictive diseases. Thru simulating various pathological conditions with the device, the clinici... | ['Airway Resistance', 'Equipment Design', 'Lung Compliance', 'Respiratory Mechanics', 'Tidal Volume', 'Ventilators, Mechanical'] | 21,706,793 | [['E01.370.386.700.050', 'G09.772.060'], ['E05.320'], ['E01.370.386.700.475', 'G09.772.540'], ['G09.772.705.700'], ['E01.370.386.700.485.750.900.350.750', 'G09.772.850.970.500.700'], ['E07.950']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Growth failure and bony changes induced by deferoxamine. | We reviewed the linear growth and growth plate morphology in all children with homozygous beta thalassemia followed in Toronto, for whom monthly height percentiles were available before, and for a 36-month period after, the initiation of nightly subcutaneous deferoxamine therapy. All patients were less than 7 years of ... | ['Alkaline Phosphatase', 'Body Height', 'Bone Development', 'Child, Preschool', 'Deferoxamine', 'Growth Plate', 'Humans', 'Radiography', 'Risk Factors', 'Thalassemia', 'Trace Elements'] | 1,550,263 | [['D08.811.277.352.650.035'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['M01.060.406.448'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['A02.835.232.251.352'], ['B01.050.150.900.649.313.988.400.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Determination of mercury in coal by isotope dilution cold-vapor generation inductively coupled plasma mass spectrometry. | A method based on isotope dilution cold-vapor inductively coupled plasma mass spectrometry (ID-CV-ICPMS) has been developed for high-accuracy determinations of mercury in bituminous and sub-bituminous coals. A closed-system digestion process employing a Carius tube is used to completely oxidize the coal matrix and chem... | ['Coal', 'Hazardous Substances', 'Mass Spectrometry', 'Mercury', 'Mercury Isotopes', 'Methods', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 12,033,233 | [['D20.345.108', 'N06.230.132.258.108'], ['D27.888.426'], ['E05.196.566'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D01.268.556.504.500', 'D01.268.956.437.500', 'D01.496.532', 'D01.552.544.504.500'], ['E05.581'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Local field potential modeling predicts dense activation in cerebellar granule cells clusters under LTP and LTD control. | Local field-potentials (LFPs) are generated by neuronal ensembles and contain information about the activity of single neurons. Here, the LFPs of the cerebellar granular layer and their changes during long-term synaptic plasticity (LTP and LTD) were recorded in response to punctate facial stimulation in the rat in vivo... | ['Action Potentials', 'Algorithms', 'Animals', 'Cell Aggregation', 'Cerebellum', 'Computer Simulation', 'Cytoplasmic Granules', 'Long-Term Potentiation', 'Long-Term Synaptic Depression', 'Models, Neurological', 'Mossy Fibers, Hippocampal', 'Neural Pathways', 'Rats'] | 21,818,278 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G17.035', 'L01.224.050'], ['B01.050'], ['G04.198.251'], ['A08.186.211.132.810.428.200'], ['L01.224.160'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['G11.561.638.350'], ['G11.561.638.355'], ['E05.599.395.642'], ['A08.186.211.180.405.200.500... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Uniform expression of Notch1, suppressor of B-cell-specific gene expression, in plasmablastic lymphoma. | CONTEXT: Although the loss of B-lineage-specific gene expression is a distinctive feature of plasmablastic lymphoma, the underlying mechanism remains poorly understood. A candidate for this mechanism is Notch1 signaling, which interferes with the activity of B-cell-specific transcription factors E2A and early B-cell fa... | ['Adaptor Proteins, Signal Transducing', 'Adult', 'Anti-HIV Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Antiretroviral Therapy, Highly Active', 'Basic Helix-Loop-Helix Transcription Factors', 'Biomarkers, Tumor', 'Cell Cycle Proteins', 'Female', 'Flow Cytometry', 'HIV Seropositivity', 'Humans', 'Immunoh... | 21,631,271 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.319.310.075'], ['D12.776.260.103', 'D12.776.930.125'], ['D23.101.140'], ['D12.776.167'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', '... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Wild rhesus monkeys generate causal inferences about possible and impossible physical transformations in the absence of experience. | Human infants and adults generate causal inferences about the physical world from observations of single, novel events, thereby violating Hume's thesis that spatiotemporal cooccurrence from prior experience drives causal perception in our species. Is this capacity unique or shared with other animals? We address this qu... | ['Animals', 'Behavior, Animal', 'Concept Formation', 'Humans', 'Infant', 'Learning', 'Macaca mulatta', 'Perception', 'Time Factors'] | 16,641,097 | [['B01.050'], ['F01.145.113'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F02.463.425', 'F02.784.629.529'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['F02.463.593'], ['G01.910.857']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of susceptibility for hip dysplasia between Rottweilers and German shepherd dogs. | Passive laxity of the coxofemoral joints, as measured quantitatively by radiographing the joints under stress, has been shown to be an accurate measure of the risk for developing degenerative joint disease (DJD) of the coxofemoral joints. Seventy-four Rottweilers between 12 and 40 months old were evaluated subjectively... | ['Age Factors', 'Animals', 'Body Weight', 'Dogs', 'Female', 'Hip Dysplasia, Canine', 'Male', 'Risk Factors', 'Sex Factors', 'Species Specificity', 'Statistics as Topic'] | 7,744,685 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.649.313.750.250.216.200'], ['C22.268.485'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.... | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice. | Dietary lipids modify brain fatty acid profile, but evidence of their direct effect on neuronal function is sparse. The enthorinal cortex (EC) neurons connecting to the hippocampus play a critical role in learning and memory. Here, we have exposed mice to diets based on canola:soybean oils (40 : 10, g/kg) or safflower ... | ['Action Potentials', 'Animals', 'Brain Chemistry', 'Data Interpretation, Statistical', 'Diet', 'Entorhinal Cortex', 'Excitatory Postsynaptic Potentials', 'Fatty Acids, Monounsaturated', 'Fatty Acids, Unsaturated', 'Flame Ionization', 'Lipids', 'Mice', 'Mice, Inbred C57BL', 'Nerve Net', 'Neurons', 'Patch-Clamp Techniqu... | 22,551,210 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['G02.111.150', 'G03.185'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G07.203.650.240'], ['A08.186.211.180.590.750.225', 'A08.186.211.180.710.225', 'A08.186.211.200.885.287.500.382.7... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Diagnostic prediction of complex diseases using phase-only correlation based on virtual sample template. | MOTIVATION: Complex diseases induce perturbations to interaction and regulation networks in living systems, resulting in dynamic equilibrium states that differ for different diseases and also normal states. Thus identifying gene expression patterns corresponding to different equilibrium states is of great benefit to th... | ['Algorithms', 'Gene Expression Profiling', 'Humans', 'Neoplasms', 'Neurodegenerative Diseases', 'Oligonucleotide Array Sequence Analysis'] | 23,815,677 | [['G17.035', 'L01.224.050'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C10.574'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Responses of the liver to perfluorinated fatty acids with different carbon chain length in male and female mice:in relation to induction of hepatomegaly, peroxisomal beta-oxidation and microsomal 1-acylglycerophosphocholine acyltransferase. | The potency of the induction of hepatomegaly, peroxisomal beta-oxidation and microsomal 1-acylglycerophoshocholine (1-acyl-GPC) acyltransferase was compared among perfluorinated fatty acids (PFCAs) with 6-9 carbon chain length in the liver of male and female mice. All PFCAs examined induced hepatomegaly and peroxisomal... | ['1-Acylglycerophosphocholine O-Acyltransferase', 'Animals', 'Body Weight', 'Caproates', 'Caprylates', 'Female', 'Fluorocarbons', 'Hepatomegaly', 'Liver', 'Male', 'Mice', 'Microsomes, Liver', 'Organ Size', 'Oxidation-Reduction', 'Peroxisomes', 'Sex Characteristics', 'Structure-Activity Relationship'] | 16,946,516 | [['D08.811.913.050.175'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.241.081.193', 'D10.251.400.326'], ['D02.241.081.222', 'D10.251.122'], ['D02.455.526.510.435'], ['C06.552.416', 'C23.300.775.525'], ['A03.620'], ['B01.050.150.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk of spring frost to apple production under future climate scenarios: the role of phenological acclimation. | In the context of global warming, the general trend towards earlier flowering dates of many temperate tree species is likely to result in an increased risk of damage from exposure to frost. To test this hypothesis, a phenological model of apple flowering was applied to a temperature series from two locations in an impo... | ['Acclimatization', 'Climate', 'Computer Simulation', 'Flowers', 'Forecasting', 'Fruit', 'Models, Biological', 'Risk Assessment', 'Risk Factors', 'Seasons', 'Weather'] | 19,263,089 | [['G07.025.133', 'G16.012.500.133'], ['G16.500.275.071', 'N06.230.300.100.250'], ['L01.224.160'], ['A18.024.249.500'], ['I01.320'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.599.395'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.80... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Diagnosis and treatment of juvenile myelomonocytic leukemia in Slovak Republic: novel approaches. | Juvenile myelomonocytic leukemia (JMML) is a rare, aggressive clonal myeloproliferative disorder of infancy and early childhood caused by oncogenic mutations in genes involved in the Ras pathway. Long-term survival has only been achieved with hematopoietic stem cell transplantation (HSCT), being able to cure more than ... | ['Azacitidine', 'Child', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Leukemia, Myelomonocytic, Juvenile', 'Male', 'Retrospective Studies', 'Slovakia'] | 31,129,971 | [['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['M01.060.406'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.525', 'C15.378.190.615.520'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Medicago truncatula Mtha1-2 mutants loose metabolic responses to mycorrhizal colonization. | Bidirectional nutrient transfer is one of the key features of the arbuscular mycorrhizal symbiosis. Recently we were able to identify a Medicago truncatula mutant (mtha1-2) that is defective in the uptake of phosphate from the periarbuscular space due to a lack of the energy providing proton gradient provided by the sy... | ['Colony Count, Microbial', 'Medicago truncatula', 'Mutation', 'Mycorrhizae', 'Phosphates', 'Photoperiod', 'Plant Proteins', 'Principal Component Analysis'] | 25,751,449 | [['E01.370.225.875.220', 'E05.200.875.220'], ['B01.650.940.800.575.912.250.401.590.750'], ['G05.365.590'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['G01.910.675'], ['D12.776.765'], ['E05.318.740.562']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Changes in pulmonary transforming growth factor-beta1/smad2 signaling pathway in a two-hit pulmonary injury as a result of uncontrolled hemorrhagic shock and lipopolysaccharide in rats]. | OBJECTIVE: To investigate the changes in pulmonary transforming growth factor-beta1 (TGF-beta1)/smad2 signaling pathway in pulmonary injury as a result of hemorrhagic shock followed by lipopolysaccharide challenge.METHODS: Twenty-four Sprague-Dawley (SD) rats were randomly assigned to the following two groups: sham ope... | ['Animals', 'Disease Models, Animal', 'Lipopolysaccharides', 'Lung', 'Lung Injury', 'RNA, Messenger', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Shock, Hemorrhagic', 'Signal Transduction', 'Smad2 Protein', 'Transforming Growth Factor beta1'] | 18,611,337 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A04.411'], ['C08.381.520', 'C26.891.554'], ['D13.444.735.544'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Discharge planning for children with perforated appendicitis. | Optimal management of children with perforated appendicitis remains a controversial clinical problem. Until very recently, the criteria for hospital discharge on our surgical service included the absence of fever and leukocytosis for a period of 48 hours following completion of antimicrobial therapy, uncomplicated woun... | ['Appendicitis', 'Body Temperature', 'Child', 'Cost-Benefit Analysis', 'Emergencies', 'Female', 'Humans', 'Intestinal Perforation', 'Length of Stay', 'Leukocyte Count', 'Male', 'Patient Discharge', 'Postoperative Care', 'Prospective Studies', 'Rupture, Spontaneous'] | 3,090,226 | [['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['E01.370.600.875.374', 'G07.110'], ['M01.060.406'], ['N03.219.151.125'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E01.370.225.500... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Turing Pattern Formation in a Semiarid Vegetation Model with Fractional-in-Space Diffusion. | A fractional power of the Laplacian is introduced to a reaction-diffusion system to describe water's anomalous diffusion in a semiarid vegetation model. Our linear stability analysis shows that the wavenumber of Turing pattern increases with the superdiffusive exponent. A weakly nonlinear analysis yields a system of am... | ['Biomass', 'Computer Simulation', 'Desert Climate', 'Ecosystem', 'Linear Models', 'Mathematical Concepts', 'Models, Biological', 'Nonlinear Dynamics', 'Plants', 'Water'] | 26,511,752 | [['G16.500.275.157.100', 'N06.230.124.100'], ['L01.224.160'], ['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['G16.500.275.157', 'N06.230.124'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.42... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
A case of vesical leiomyoma and acute urinary obstruction. | A case of acute urinary retention due to a vesical leiomyoma is described. This is an unusual presentation and the treatment is discussed. | ['Acute Disease', 'Adult', 'Female', 'Humans', 'Leiomyoma', 'Urinary Bladder Neck Obstruction', 'Urinary Bladder Neoplasms', 'Urination Disorders'] | 6,634,549 | [['C23.550.291.125'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['C12.777.767.700.962', 'C12.777.829.760', 'C13.351.968.767.700.850', 'C13.351.968.829.601'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707'], ['C1... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression profiling of metalloproteinases and their inhibitors in cartilage. | OBJECTIVE: To profile the expression of all known members of the matrix metalloproteinase (MMP), ADAMTS, and tissue inhibitor of metalloproteinases (TIMP) gene families in normal cartilage and cartilage from patients with osteoarthritis (OA).METHODS: Human cartilage was obtained from femoral heads at joint replacement ... | ['ADAM Proteins', 'ADAMTS1 Protein', 'Adult', 'Aged', 'Aged, 80 and over', 'Cartilage', 'Disintegrins', 'Female', 'Femur', 'Fractures, Bone', 'Gene Expression Profiling', 'Humans', 'Male', 'Metalloendopeptidases', 'Metalloproteases', 'Middle Aged', 'Osteoarthritis, Hip', 'Tissue Inhibitor of Metalloproteinases'] | 14,730,609 | [['D08.811.277.656.675.374.102', 'D09.400.430.500', 'D12.776.395.033'], ['D08.811.277.656.675.374.102.500.500', 'D09.400.430.500.500.500', 'D12.776.395.033.500.500', 'D12.776.860.300.085.500'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.165', 'A10.165.382'], ['D12.644.138'], ['A02.835.232.043.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Equilibrium distribution of polysulfide ions in aqueous solutions at different temperatures by rapid single phase derivatization. | Polysulfides are abundant form of reduced sulfur compounds whose distribution in aquatic systems continues to pose environmental challenge. The Gibbs free-energy of formation, enthalpy of formation, and standard entropy of inorganic polysulfides were derived based on measurements of the temperature-dependent distributi... | ['Sulfides', 'Temperature', 'Thermodynamics', 'Water', 'Water Pollutants, Chemical'] | 17,438,792 | [['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors. | Cholesterol-rich lipid rafts act as signaling microdomains and can regulate receptor function. We have shown in HEK293 cells recombinant P2X1-4 receptors (ATP-gated ion channels) are expressed in lipid rafts. Localization to flotillin-rich lipid rafts was reduced by the detergent Triton X-100. This sensitivity to Trito... | ['Adenosine Triphosphate', 'Cell Line', 'Cholesterol', 'Humans', 'Ion Channel Gating', 'Membrane Microdomains', 'Membrane Potentials', 'Mutation', 'Purinergic P2X Receptor Agonists', 'Receptors, Purinergic P2X1', 'Receptors, Purinergic P2X2', 'Receptors, Purinergic P2X3', 'Receptors, Purinergic P2X4', 'Recombinant Fusi... | 20,699,225 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.251.210'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['A11.284.149.165.570'], ['G01.154.535', 'G04.58... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. | Transfection of genes into tissue culture cell lines has demonstrated that relatively short DNA sequences can allow expression of immunoglobulin, insulin and chymotrypsin genes in their appropriate cell types. A definitive test of cell-specific gene expression, however, requires testing genes in every possible cell typ... | ['Animals', 'DNA, Recombinant', 'Gene Expression Regulation', 'Growth Hormone', 'Humans', 'Mice', 'Organ Specificity', 'Pancreas', 'Pancreatic Elastase', 'RNA, Messenger', 'Rats', 'Species Specificity', 'Transformation, Genetic'] | 3,844,051 | [['B01.050'], ['D13.444.308.460'], ['G05.308'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G07.650'], ['A03.734'], ['D08.811.277.656.300.760.560', 'D08.811.277.656.959.350.560'], ['D13.444.735.544'], ['B01.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognosis of individuals with asymptomatic left ventricular systolic dysfunction in the multi-ethnic study of atherosclerosis (MESA). | BACKGROUND: Limited data exist on the prevalence, associations, and prognosis of individuals with asymptomatic left ventricular systolic dysfunction (ALVSD), especially in populations without previous clinical cardiovascular disease (CVD).METHODS AND RESULTS: Kaplan-Meier and Cox proportional hazard analyses were used ... | ['Aged', 'Aged, 80 and over', 'Asymptomatic Diseases', 'Atherosclerosis', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Heart Failure, Systolic', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Prospective Studies', 'Ventricular Dysfunction, Left'] | 23,124,035 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.187'], ['C14.907.137.126.307'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434.676'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of a novel aspartic protease (Asp 2) as beta-secretase. | The Alzheimer's disease beta-amyloid peptide (Abeta) is produced by excision from the type 1 integral membrane glycoprotein amyloid precursor protein (APP) by the sequential actions of beta- and then gamma-secretases. Here we report that Asp 2, a novel transmembrane aspartic protease, has the key activities expected of... | ['Alzheimer Disease', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Amyloid Precursor Protein Secretases', 'Amyloid beta-Protein Precursor', 'Animals', 'Aspartic Acid Endopeptidases', 'COS Cells', 'Cathepsin D', 'Cell Line', 'Cell Membrane', 'Endopeptidases', 'Female', 'Hippocampus', 'Humans', 'Middle Aged', 'Mole... | 10,656,250 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D08.811.277.656.300.032'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['D08.811.277.656.074.500', 'D08.811.277.656... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Gene expression profile in mouse myocardium after ischemia. | This study was designed to elaborate a molecular profile of expressed genes during ischemic injury to the mouse heart after surgical constriction of the left coronary artery without reperfusion. A mouse cDNA array containing 588 known genes was used to compare gene expression in heart RNA after 24-h ischemia with contr... | ['Animals', 'Carrier Proteins', 'Cell Cycle Proteins', 'Cyclin-Dependent Kinase Inhibitor p18', 'DNA-Binding Proteins', 'Disease Models, Animal', 'Early Growth Response Protein 1', 'Early Growth Response Protein 3', 'Enzyme Inhibitors', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Glutathione Transferase... | 11,015,587 | [['B01.050'], ['D12.776.157'], ['D12.776.167'], ['D12.644.360.225.300', 'D12.776.167.187.300', 'D12.776.476.225.300', 'D12.776.624.776.355.300'], ['D12.776.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.260.158.500', 'D12.776.460.525.500', 'D12.776.930.213.500'], ['D12.776.260.158.875', 'D12.776.460.52... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduction of serum free fatty acids and triglycerides by liver-targeted expression of long chain acyl-CoA synthetase 3. | ACSL3 is a member of the long chain acyl-CoA synthetase (ACSL) family that consists of 5 isozymes responsible for cellular fatty acid metabolism in various tissues in an isozyme-specific manner. Our previous studies have demonstrated that expression of ACSL3 mRNA and protein in liver was specifically increased after fe... | ['Animals', 'Animals, Genetically Modified', 'Coenzyme A Ligases', 'Cricetinae', 'Endoplasmic Reticulum', 'Enzyme Assays', 'Fatty Acids', 'Green Fluorescent Proteins', 'Hep G2 Cells', 'Humans', 'Liver', 'Male', 'Mesocricetus', 'Mitochondria, Liver', 'Phospholipids', 'Recombinant Proteins', 'Triglycerides'] | 21,347,510 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['D08.811.464.267.500'], ['B01.050.150.900.649.313.992.635.075.250'], ['A11.284.430.214.190.875.248'], ['E05.196.427'], ['D10.251'], ['D12.776.532.265'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['B01.050.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Penicillium marneffei: types and drug susceptibility. | The PCR fingerprints of 30 Penicillium marneffei isolates from Chiang Rai in Northern Thailand and Bangkok in central Thailand were studied through use of single-nucleotide primers (GACA)4 and the phage M13 core sequence. Discrimination of fingerprint patterns was based on differences in the number of major bands. The ... | ['Antifungal Agents', 'DNA Fingerprinting', 'DNA, Fungal', 'Electrophoresis', 'Female', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Mycoses', 'Penicillium', 'Polymerase Chain Reaction', 'Thailand'] | 11,307,592 | [['D27.505.954.122.136'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D13.444.308.300'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['C01.150.703'], ['B01.300.381.662'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Sanitary conditions of community dining halls in greater Buenos Aires, Argentina]. | Because of the importance of food safety for public health, a study was done to determine the microbiologic quality of foods provided to patrons of community dining halls in greater Buenos Aires, Argentina. The study was descriptive and was conducted in three municipalities with intermediate or high poverty indices; a ... | ['Adolescent', 'Adult', 'Aged', 'Argentina', 'Child', 'Food Microbiology', 'Humans', 'Middle Aged', 'Restaurants', 'Urban Health'] | 9,445,768 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.107.757.077'], ['M01.060.406'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.576.423.500.700',... | ['Named Groups [M]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
Poison center operations: the necessity of follow-up. | A retrospective study of 2,526 calls made to a regional poison center demonstrated the value of telephone follow-up of poison exposures. Further treatment recommendations were required in 21.2% of follow-up calls, more than 25% of which were made to physicians. Poison prevention education and data collection were accom... | ['Child', 'Child, Preschool', 'Data Collection', 'District of Columbia', 'Follow-Up Studies', 'Health Education', 'Hospital Bed Capacity, 300 to 499', 'Humans', 'Infant', 'Poison Control Centers', 'Poisoning', 'Regional Health Planning', 'Retrospective Studies', 'Telephone', 'United States'] | 7,091,793 | [['M01.060.406'], ['M01.060.406.448'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.107.567.875.500.210', 'Z01.433.429'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I02.233.332', 'N02.421.726.407'], ['N02.278.306.472.180'], ['B01.050.150.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Laparoscopic inguinal preperitoneal injection--novel technique for inguinal hernia repair: preliminary results of experimental study. | BACKGROUND: Inguinal hernia repair is the most common procedure in pediatric surgery. Suture techniques for laparoscopic inguinal hernia repair in children are easy to perform and popular with a low recurrence rate. The aim of this study was to evaluate the effect of laparoscopic preperitoneal injection of three-dimens... | ['Acrylic Resins', 'Animals', 'Chinchilla', 'Disease Models, Animal', 'Hernia, Inguinal', 'Herniorrhaphy', 'Injections', 'Laparoscopy', 'Male', 'Prostheses and Implants', 'Silver', 'Silver Compounds'] | 22,356,207 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['B01.050'], ['B01.050.150.900.649.313.992.328'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.300.707.374.875'], ['E04.680.325'], ['E02.319.267.530'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E07.695'], ['D01.268.556.812', 'D0... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Marriage as a public issue. | Over the past fifty years, powerful cultural and social forces have made marriage less central to Americans' family lives. In reaction, the United States is now engaged in a wide-ranging debate about the place of marriage in contemporary society. In this article, Steven Nock examines the national marriage debate. He be... | ['Adult', 'Child', 'Female', 'Government Programs', 'Health Behavior', 'Humans', 'Male', 'Marriage', 'Parents', 'Public Opinion', 'Religion', 'Sexual Behavior', 'Social Change', 'United States'] | 16,158,728 | [['M01.060.116'], ['M01.060.406'], ['I01.451'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308.500.500'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['I01.880.630.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Protective effects of vitamins E, B and C and L-carnitine in the prevention of cisplatin-induced ototoxicity in rats. | OBJECTIVE: This experimental study aimed to investigate the effects of vitamins E, B and C and L-carnitine in preventing cisplatin-induced ototoxicity.METHODS: Twenty-five adult, male, Wistar albino rats were randomly allocated to receive intraperitoneal cisplatin either alone or preceded by vitamins B, E or C or L-car... | ['Analysis of Variance', 'Animals', 'Antineoplastic Agents', 'Antioxidants', 'Ascorbic Acid', 'Carnitine', 'Cisplatin', 'Evoked Potentials, Auditory, Brain Stem', 'Hearing Loss', 'Humans', 'Male', 'Otoacoustic Emissions, Spontaneous', 'Rats', 'Rats, Wistar', 'Signal-To-Noise Ratio', 'Vitamin B Complex', 'Vitamin E'] | 22,490,890 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.954.248'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D02.092.877.883.099'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G07.265.216.500.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of isotretinoin on eccrine gland function. | Sweat secretion rate, stimulated by iontophoresis of pilocarpine, was measured before and during treatment with isotretinoin in 20 patients. Sweat secretion was increased during treatment in 15 patients (75%), but the mean increase of 15% was not statistically significant (P = 0.085, paired t-test; 95% confidence limit... | ['Adolescent', 'Adult', 'Eccrine Glands', 'Female', 'Humans', 'Isotretinoin', 'Male', 'Sweat Glands', 'Sweating', 'Tretinoin'] | 3,165,666 | [['M01.060.057'], ['M01.060.116'], ['A10.336.899.480', 'A17.815.830.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665.202.495.325', 'D02.455.426.392.368.367.379.249.700.325', 'D02.455.849.131.495.325', 'D23.767.261.700.325'], ['A10.336.899', 'A17.815.830'], ['G07.110.232.693', 'G07.410.421.6... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hormone replacement therapy and peripheral arterial disease: the Rotterdam study. | BACKGROUND: As the number of elderly women increases in Western society, peripheral arterial disease (PAD) is likely to become an increasing problem. Hormone replacement therapy, suggested to protect against coronary atherosclerosis, might also inhibit the development of PAD.METHODS: The association between hormone rep... | ['Aged', 'Aged, 80 and over', 'Estrogen Replacement Therapy', 'Female', 'Humans', 'Logistic Models', 'Middle Aged', 'Netherlands', 'Peripheral Vascular Diseases', 'Treatment Outcome'] | 10,979,062 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.319.452.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830.500.525'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A likelihood ratio test of population Hardy-Weinberg equilibrium for case-control studies. | Testing Hardy-Weinberg equilibrium (HWE) in the control group is commonly used to detect genotyping errors in genetic association studies. We propose a likelihood ratio test for testing HWE in the study population using both case and control samples. This test incorporates underlying association models. Another feature... | ['Case-Control Studies', 'Disease', 'Genetics, Population', 'Genotype', 'Humans', 'Hypertension', 'Hypertension, Pulmonary', 'Likelihood Functions', 'Models, Genetic'] | 19,025,784 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.288'], ['H01.158.273.343.335'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C08.381.423', 'C14.907.489.556'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Mycobacterium tuberculosis lipolytic enzymes as potential biomarkers for the diagnosis of active tuberculosis. | BACKGROUND: New diagnosis tests are urgently needed to address the global tuberculosis (TB) burden and to improve control programs especially in resource-limited settings. An effective in vitro diagnostic of TB based on serological methods would be regarded as an attractive progress because immunoassays are simple, rap... | ['BCG Vaccine', 'Biomarkers', 'Communicable Disease Control', 'Enzyme-Linked Immunosorbent Assay', 'Escherichia coli', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Immunologic Tests', 'Lipolysis', 'Mycobacterium smegmatis', 'Mycobacterium tuberculosis', 'Proteomics', 'Recombinant Proteins', 'Sensitivity and Speci... | 21,966,416 | [['D20.215.894.135.825.100'], ['D23.101'], ['N06.850.780.200'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393'... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Time to prostate specific antigen recurrence after radical prostatectomy and risk of prostate cancer specific mortality. | PURPOSE: In patients treated with radical prostatectomy who have biochemical recurrence we have previously reported that time from surgery to biochemical recurrence and postoperative prostate specific antigen doubling time are significantly related to the risk of prostate cancer death. We performed a more thorough exam... | ['Aged', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neoplasms', 'Retrospective Studies', 'Survival Rate', 'Time Factors'] | 16,952,644 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.500', 'D23.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative Analysis of Continuous Suturing, Interrupted Suturing, and Cyanoacrylate-Based Lid Techniques for End-to-End Microvascular Anastomosis: Laboratory Investigation. | BACKGROUND: Mastery of the microsurgical anastomosis is an indispensable component of neurosurgical training. However, in many resource-limited countries, the training, materials, and equipment to obtain these surgical and decision making skills are severely lacking. This study aimed to compare different suturing techn... | ['Anastomosis, Surgical', 'Cyanoacrylates', 'Humans', 'Neurosurgical Procedures', 'Suture Techniques', 'Tissue Adhesives'] | 31,734,417 | [['E04.035'], ['D02.241.081.069.366', 'D02.626.290', 'D05.750.259', 'D25.720.259', 'D25.919.367', 'J01.637.051.720.259', 'J01.637.051.919.367'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.525'], ['E04.987.775'], ['D25.919', 'D27.720.102.919', 'E07.858.690.860', 'J01.637.051.919']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Reduced incidence of extra-articular manifestations of RA through effective disease control: Karnataka Rheumatoid Arthritis Comorbidity (KRAC) study. | AIM: To estimate the prevalence of extra-articular manifestations (EAM) in rheumatoid arthritis (RA) patients and the impact of demographic, clinical and treatment factors.METHOD: The study was carried out as a part of 'Karnataka Rheumatoid arthritis comorbidity (KRAC) study' conducted at 14 centers across Karnataka, I... | ['Adult', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Chi-Square Distribution', 'Comorbidity', 'Cross-Sectional Studies', 'Female', 'Humans', 'Incidence', 'India', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Prevalence', 'Prospective Studies', 'Risk Factors', 'Severity of Ill... | 27,943,575 | [['M01.060.116'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The genetic structure of populations of the vulnerable aquatic macrophyte Ranunculus nipponicus (Ranunculaceae). | Ranunculus nipponicus (Makino) Nakai is a vulnerable aquatic macrophyte in the Kinki district, which is the southernmost distribution of this species in Japan. The genetic diversity and structure within and among eleven extant populations were assessed using the inter-simple sequence repeats (ISSR) polymerase chain rea... | ['DNA, Plant', 'Genetic Markers', 'Genetic Variation', 'Geography', 'Japan', 'Phylogeny', 'Ranunculus', 'Repetitive Sequences, Nucleic Acid', 'Sampling Studies'] | 17,351,831 | [['D13.444.308.435'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['H01.277.500'], ['Z01.252.474.463', 'Z01.639.595'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.650.940.800.575.912.250.836.750.733'], ['G02.111.570.080.708', 'G05.360.080.708'], ['E05.318.372.875', 'N05.715.360.330.875', 'N06.850.520.450.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
General adaptation syndrome and magnetostatic field: effects on sleep and delayed reinforcement of low rate. | In order to study the effects of a magnetostatic field on the organism, continuous exposure was applied and the resulting effects were observed for a period of 20 days. The Ss were four rats which were continually exposed, one by one, to a vertical field of 2800 oersted for uninterrupted periods of time. In a first ser... | ['Adaptation, Psychological', 'Animals', 'Conditioning, Operant', 'Electromagnetic Fields', 'Electromagnetic Phenomena', 'Rats', 'Reinforcement Schedule', 'Sleep'] | 625,027 | [['F01.058'], ['B01.050'], ['F02.463.425.179.509'], ['G01.358.500.260', 'G01.358.750.500'], ['G01.358.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['F02.463.425.770.644'], ['F02.830.855', 'G11.561.803']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plan to win your career battle. | It is ironic that the central focus of our profession is predicated on our ability to plan; however, when the subject of career planning is discussed, we often leave it to change. Our career should be a series of planned events. The notion of doing a good job is no longer the key to a career. We must be proactive and d... | ['Attitude', 'Career Mobility', 'Education', 'Humans', 'Internal-External Control', 'Job Satisfaction', 'Planning Techniques', 'Staff Development', 'United States'] | 10,142,108 | [['F01.100'], ['N01.824.245.175', 'N01.824.547.330'], ['I02'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F02.784.692.425'], ['N04.452.718'], ['I02.574.700', 'N04.452.677.822'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
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