Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Modified Hauser operation for patellar instability. Immediate mobilization of 35 knees, a 5-8 year follow-up study. | We performed a follow-up examination of 35 knees with chronic patellar instability treated by a modified Hauser operation: medialization and distalization of the tibial tubercle without dorsal transfer, and fixation of the tubercle rigidly with 2 cortical screws. Cast immobilization was not used and the patients were a... | ['Adolescent', 'Adult', 'Female', 'Follow-Up Studies', 'Humans', 'Joint Dislocations', 'Joint Instability', 'Knee Joint', 'Male', 'Middle Aged', 'Orthopedics', 'Patella', 'Recurrence'] | 8,948,249 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['C05.550.521'], ['A02.835.583.475'], ['M01.060.116.630'], ['H02.403.810.494'], ['A02.835.232.043.650.624', 'A02.835.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of the microbial community in indoor environments: a chemical-analytical approach. | An integrated procedure is presented whereby gas chromatography-ion trap mass spectrometry is used to determine chemical markers of gram-negative bacterial lipopolysaccharide (3-hydroxy fatty acids with 10 to 18 carbon atoms), gram-positive bacteria (branched-chain fatty acids with 15 and 17 carbon atoms), bacterial pe... | ['Air Pollution, Indoor', 'Bacteria', 'Bacteriological Techniques', 'Biomarkers', 'Biomass', 'Dust', 'Ergosterol', 'Fatty Acids', 'Fungi', 'Gas Chromatography-Mass Spectrometry', 'Lipopolysaccharides', 'Muramic Acids', 'Reproducibility of Results'] | 12,788,704 | [['N06.850.460.100.080'], ['B03'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D23.101'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D20.633.222'], ['D04.210.500.247.222.537'], ['D10.251'], ['B01.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525',... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Abnormal facilitatory mechanisms in motor cortex of migraine with aura. | Experimental evidence suggests impairment of inhibitory intracortical circuits in migraine, while not much is known about activity of facilitatory intracortical circuits. In the present work we evaluated the effects of high frequency-repetitive transcranial magnetic stimulation (hf-rTMS) on the activity of facilitatory... | ['Adult', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Levetiracetam', 'Male', 'Migraine with Aura', 'Motor Cortex', 'Nerve Net', 'Neurons', 'Piracetam', 'Transcranial Magnetic Stimulation'] | 21,530,338 | [['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.064.432', 'D02.241.081.018.110.463', 'D03.383.773.812.362'], ['C10.228.140.546.399.750.250'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lectin/glycan interactions play a role in recognition in a coral/dinoflagellate symbiosis. | Recognition is an important stage in the establishment of highly specific mutualistic associations. Yet, for the majority of symbioses, very few of the mechanisms involved in recognition and specificity are known. In this study, we provide evidence for a recognition mechanism at the onset of symbiosis between larvae of... | ['Animals', 'Anthozoa', 'Dinoflagellida', 'Eukaryota', 'Galactose', 'Glucose', 'Lectins', 'Life Cycle Stages', 'Mannose', 'Polysaccharides', 'Symbiosis'] | 16,879,456 | [['B01.050'], ['B01.050.500.308.237'], ['B01.043.214'], ['B01'], ['D09.947.875.359.377'], ['D09.947.875.359.448'], ['D12.776.503'], ['B05.500', 'G07.345.500.550.500'], ['D09.947.875.359.588'], ['D09.698'], ['G06.550.800', 'G16.840']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of cobalt (dietary), cobalamins, and inorganic cobalt salts on phenytoin- and cortisone-induced teratogenesis in mice. | Various cobalt-containing agents (cyanocobalamin, sodium cobaltinitrite, and cobaltous chloride), which formerly had been shown to prevent the onset of cleft palate in CF-1 mice injected with cortisone, were studied to determine whether they would afford similar protection against phenytoin. Phenytoin, however, failed ... | ['Animals', 'Body Weight', 'Cobalt', 'Cortisone', 'Female', 'Fetus', 'Male', 'Maternal-Fetal Exchange', 'Mice', 'Organ Size', 'Phenytoin', 'Pregnancy', 'Sex Ratio', 'Teratogens', 'Vitamin B 12'] | 641,728 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['D04.210.500.745.745.183', 'D06.472.040.585.478.195'], ['A16.378'], ['G08.686.784.769.455'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Fourier transform infrared imaging showing reduced unsaturated lipid content in the hippocampus of a mouse model of Alzheimer's disease. | Polyunsaturated fatty acids are essential to brain functions such as membrane fluidity, signal transduction, and cell survival. It is also thought that low levels of unsaturated lipid in the brain may contribute to Alzheimer's disease (AD) risk or severity. However, it is not known how accumulation of unsaturated lipid... | ['Alzheimer Disease', 'Animals', 'Disease Models, Animal', 'Fatty Acids, Unsaturated', 'Hippocampus', 'Humans', 'Mice', 'Oxidation-Reduction', 'Principal Component Analysis', 'Spectroscopy, Fourier Transform Infrared'] | 20,187,625 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D10.251.355'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.700', 'G03.295.531'... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein. | The zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses by eliminating viral mRNAs in the cytoplasm. In previous studies, we demonstrated that ZAP directly binds to the viral mRNAs and recruits the RNA exosome to degrade the target RNA. In this article, we ... | ['Cytoplasm', 'DEAD-box RNA Helicases', 'Humans', 'Immunoprecipitation', 'Protein Binding', 'RNA', 'RNA Helicases', 'RNA, Messenger', 'RNA, Viral', 'RNA-Binding Proteins'] | 21,204,022 | [['A11.284.430.214'], ['D08.811.913.696.445.735.720.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.150.639', 'E05.478.605'], ['G02.111.679', 'G03.808'], ['D13.444.735'], ['D08.811.913.696.445.735.720'], ['D13.444.735.544'], ['D13.444.735.828'], ['D12.776.157.725', 'D12.776.664.962']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A clinical tool to measure the components of health-care transition from pediatric care to adult care: the UNC TR(x)ANSITION scale. | OBJECTIVE: To describe the development of the University of North Carolina (UNC) TR(x)ANSITION Scale that measures the health-care transition and self-management skills by youth with chronic health conditions.METHODS: Item and scale development of the UNC TR(x)ANSITION Scale was informed by two theoretical models, avai... | ['Adolescent', 'Child', 'Disease Management', 'Feedback', 'Female', 'Focus Groups', 'Health Transition', 'Humans', 'Hypertension', 'Inflammatory Bowel Diseases', 'Interviews as Topic', 'Kidney Diseases', 'Kidney Transplantation', 'Male', 'Models, Theoretical', 'North Carolina', 'Pilot Projects', 'Psychometrics', 'Repro... | 22,583,152 | [['M01.060.057'], ['M01.060.406'], ['N04.590.607'], ['L01.906.394.211'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['I01.240.600.400', 'N01.224.625.400', 'N06.850.505.400.700.400', 'N06.850.650'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C06.405.205.731', 'C06.405.469... | ['Named Groups [M]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Evaluation of the hemodynamics in straight 6-mm and tapered 6- to 8-mm grafts as upper arm hemodialysis vascular access. | The present study is intended to investigate and compare the hemodynamics in two different sizes of hemodialysis arteriovenous grafts for upper arm hemodialysis vascular access: 8-mm tapered to 6-mm at the arterial side and straight 6 mm. A computational simulation approach is presented for this study, which is validat... | ['Arm', 'Arteries', 'Blood Vessel Prosthesis', 'Computer Simulation', 'Hemodynamics', 'Humans', 'Imaging, Three-Dimensional', 'Models, Cardiovascular', 'Renal Dialysis', 'Transplants'] | 25,112,274 | [['A01.378.800.075'], ['A07.015.114'], ['E07.695.110'], ['L01.224.160'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.599.395.161'], ['E02.870.300', 'E02.912.800'], ['A01.941']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Angiogenic effects of dual gene transfer of bFGF and PDGF-BB after myocardial infarction. | Therapeutic effects of combination of angiogenic growth factors for the treatment of ischemia after myocardial infarction are largely unknown. Plasmids expressing basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF-BB) or their combination with a 1:1 mass ratio were injected into hearts with 7-d... | ['Animals', 'Arterioles', 'Capillaries', 'Disease Models, Animal', 'Drug Synergism', 'Fibroblast Growth Factor 2', 'Gene Transfer Techniques', 'Genetic Therapy', 'Humans', 'Myocardial Infarction', 'Neovascularization, Physiologic', 'Organ Size', 'Plasmids', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Platelet-Derived G... | 14,985,120 | [['B01.050'], ['A07.015.114.060', 'A07.015.461.080'], ['A07.015.461.165'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.968.477'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C1... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphological changes in degrading PLGA and P(DL)LA microspheres: implications for the design of controlled release systems. | The in vitro degradation of microspheres of polymers of lactic and glycolic acids were investigated by monitoring the mass loss from the device, the molecular weight of the polymer and the morphological changes of the particles with time. Two different sequences of morphological changes were found to be operative, depe... | ['Biocompatible Materials', 'Biodegradation, Environmental', 'Capsules', 'Delayed-Action Preparations', 'Drug Compounding', 'Drug Delivery Systems', 'In Vitro Techniques', 'Lactic Acid', 'Microscopy, Electron, Scanning', 'Microspheres', 'Molecular Weight', 'Particle Size', 'Polyesters', 'Polyglycolic Acid', 'Polylactic... | 11,695,641 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D26.255.150'], ['D26.255.210', 'E02.319.300.253'], ['E05.916.270'], ['E02.319.300'], ['E05.481'], ['D02.241.511.459.450'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E07.565'], ['G02.494'], ['G02.712'], ['D05.75... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The reliability of positioning pre-adjusted brackets: an in vitro study. | To investigate the reliability of bracket positioning, twelve operators, familiar with the straight-wire appliance, placed 0.022" straight-wire brackets on the anterior teeth of a typodont study model, on three different occasions. Bracket position was assessed using a Magiscan image analyser. Angular judgements by the... | ['Cuspid', 'Dental Models', 'Humans', 'Image Processing, Computer-Assisted', 'Incisor', 'Observer Variation', 'Orthodontic Brackets', 'Orthodontic Wires', 'Reproducibility of Results', 'Surface Properties', 'Tooth Movement Techniques'] | 1,562,576 | [['A14.549.167.860.200'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A14.549.167.860.425'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E06.658.453.255.500'], ['E06.658.453.684'], ... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Improvement in attitudes toward the elderly following traditional and geriatric mock clinics for physical therapy students. | The purpose of this study was to determine whether the attitudes of students in a physical therapy education program toward the elderly could be influenced positively by (1) having classroom discussion led by an individual with expertise in geriatrics and (2) having only individuals aged 65 years or older participate i... | ['Adult', 'Aging', 'Attitude of Health Personnel', 'Female', 'Geriatrics', 'Humans', 'Male', 'Middle Aged', 'Physical Therapy Modalities', 'Program Evaluation', 'Role Playing', 'Stereotyping', 'Students', 'Surveys and Questionnaires', 'Teaching'] | 1,584,858 | [['M01.060.116'], ['G07.345.124'], ['F01.100.050', 'N05.300.100'], ['H02.403.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.779', 'E02.831.535'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['E02.190.525.781.653', 'F04.754.864.581.679.653'], ['F01.100.920', 'F01.145.813.854'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Colloidal gold immunochromatographic strip for rapid detection of Haemophilus influenzae]. | To establish a novel colloidal gold immunochromatography assay (GICA) for rapid, sensitive and accurate detection of Haemophilus influenzae infection by using the outer membrane protein P6 as detection target. First, the linear antigen epitope located in the extracellular domain of the P6 protein (GenBank accession num... | ['Animals', 'Chromatography, Affinity', 'Diagnostic Tests, Routine', 'Gold Colloid', 'Haemophilus Infections', 'Haemophilus influenzae', 'Humans', 'Limit of Detection', 'Rabbits', 'Sensitivity and Specificity'] | 31,223,008 | [['B01.050'], ['E05.196.181.400.170'], ['E01.370.395'], ['D01.379.400'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['B01.050.150.900.649.313.968.700'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetic moderation of contextual effects on negative arousal and parenting in African-American parents. | A three-stage context amplification model was tested with a sample of 345 African-American parent-child dyads. The model combined the conceptual structure of stress generation with recent findings regarding genetic susceptibility. Because the 7R + allele of the dopamine transporter (DRD4) has the potential to enhance c... | ['African Americans', 'Alleles', 'Arousal', 'Female', 'Genotype', 'Georgia', 'Humans', 'Interviews as Topic', 'Iowa', 'Longitudinal Studies', 'Male', 'Parent-Child Relations', 'Parenting', 'Receptors, Dopamine D4', 'Regression Analysis', 'Stress, Psychological', 'Young Adult'] | 22,081,909 | [['M01.686.508.100.100', 'M01.686.754.100'], ['G05.360.340.024.340.030'], ['F02.830.104', 'G11.561.035'], ['G05.380'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.107.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Functional MRI of inhibitory processing in abstinent adolescent marijuana users. | BACKGROUND: Marijuana intoxication appears to impair response inhibition, but it is unclear if impaired inhibition and associated brain abnormalities persist after prolonged abstinence among adolescent users. We hypothesized that brain activation during a go/no-go task would show persistent abnormalities in adolescent ... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Analysis of Variance', 'Decision Making', 'Female', 'Gyrus Cinguli', 'Humans', 'Inhibition, Psychological', 'Magnetic Resonance Imaging', 'Male', 'Marijuana Abuse', 'Oxygen', 'Parietal Lobe', 'Prefrontal Cortex', 'Psychiatric Status Rating Scales', 'Task Performance and A... | 17,558,500 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.463.785.373'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['E01.37... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nutritional state, maturational delay on electroencephalogram, and developmental outcome in extremely low birth weight infants. | The aim of this study is to clarify the relation among developmental outcome, nutritional state during the neonatal period, maturational electroencephalographic changes. Thirteen extremely low birth weight infants who completed 6- or 9-year follow-up were a subject of this study. Undernutrition was defined as enteral f... | ['Body Height', 'Body Weight', 'Child', 'Child Development', 'Electroencephalography', 'Enteral Nutrition', 'Female', 'Gestational Age', 'Humans', 'Infant, Extremely Low Birth Weight', 'Infant, Newborn', 'Intelligence', 'Male', 'Nutritional Status', 'Pregnancy'] | 19,819,655 | [['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['E01.370.376.300', 'E01.370.405.245'], ['E02.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Function of alternative NF-êB activity in B-cell chronic lymphocytic leukemia cells]. | OBJECTIVE: To investigate the function of alternative NF-êB activity in B-cell chronic lymphocytic leukemia cells (B-CLL).METHODS: The mRNA expression of individual NF-êB subunits in CD5⁺CD19⁺ cells (CLL B-cells) from bone marrow (BM) of 56 patients with B-CLL was analyzed by quantitative RT-PCR. An ELISA-based NF-êB f... | ['Case-Control Studies', 'Cell Nucleus', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'NF-kappa B p50 Subunit', 'NF-kappa B p52 Subunit', 'Transcription Factor RelA', 'Transcription Factor RelB', 'Tumor Cells, Cultured'] | 24,602,731 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20.683.515.528.080.125'], ['D12.776.260.600.124', 'D12.776.660.600.124', 'D12.776.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors. | B-1 cells spontaneously secrete natural Ig that acts as a primary line of defense against infection. A major shortfall in our understanding of this key process centers on the molecular mechanisms regulating natural Ab secretion by B-1 cells. Herein, we demonstrate that secreting B-1 cells use some aspects of the recent... | ['Animals', 'B-Lymphocyte Subsets', 'Base Sequence', 'Cell Differentiation', 'DNA, Complementary', 'DNA-Binding Proteins', 'Gene Expression', 'Immunity, Innate', 'Immunoglobulins', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Nuclear Proteins', 'PAX5 Transcription Factor', 'Plasma Cells', 'Positive Regulatory Domain I-Bindi... | 15,749,846 | [['B01.050'], ['A11.063.438.450', 'A11.118.637.555.567.550.450', 'A11.118.637.555.567.562.200', 'A15.145.229.637.555.567.550.450', 'A15.145.229.637.555.567.562.200', 'A15.382.032.438.450', 'A15.382.490.555.567.550.300', 'A15.382.490.555.567.562.450'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.152... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Trends in live demonstrations of cardiovascular surgery in Japan and the ideal form of live demonstration]. | Live demonstrations of cardiovascular surgery are performed following guidelines instituted in 2007. The guidelines suggest that standard procedures should be selected and performed at institutions qualified by the Japanese Board of Cardiovascular Surgery. Live demonstrations should be approved by each institutional re... | ['Cardiovascular Surgical Procedures', 'Education, Medical, Continuing', 'Guidelines as Topic', 'Humans', 'Japan'] | 23,789,329 | [['E04.100'], ['I02.358.212.350', 'I02.358.399.250'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Characterization of an insulin-like growth factor binding protein, analogous to human pregnancy-associated secreted endometrial alpha 1-globulin, in decidua of the baboon (Papio anubis) placenta. | The major secreted protein of the human decidua (pregnancy-associated endometrial alpha 1-globulin [alpha 1-PEG]), is an insulin-like growth factor-binding protein (IGF-BP) that is immunologically and biochemically similar to placental protein 12 (PP12) extracted from term human placenta. Since previous studies have de... | ['Animals', 'Blotting, Western', 'Carrier Proteins', 'Chromatography, Gel', 'Culture Techniques', 'Cytosol', 'Decidua', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Glycodelin', 'Humans', 'Immunohistochemistry', 'Immunosorbent Techniques', 'Insulin-Like Growth Factor Binding Proteins', 'Intracellular Signaling Pep... | 2,473,788 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157'], ['E05.196.181.400.250'], ['E05.481.500'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['A05.360.319.679.490.373', 'A16.710.289'], ['E05.196.401.402', 'E05.301.30... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Musicians and the gamma band: a secret affair? | While listening to music, a significant high degree of phase synchrony in the gamma frequency range globally distributed over the brain was found in subjects with musical training (musicians) compared with subjects with no such training (non-musicians). No significant differences were found in other EEG frequency bands... | ['Adult', 'Auditory Perception', 'Cerebral Cortex', 'Cortical Synchronization', 'Dominance, Cerebral', 'Humans', 'Male', 'Memory', 'Music'] | 11,209,952 | [['M01.060.116'], ['F02.463.593.071', 'G07.888.125'], ['A08.186.211.200.885.287.500'], ['E01.370.376.300.437.500', 'E01.370.405.245.575.500', 'G07.265.256.249'], ['F02.830.297', 'G11.561.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['K01.602']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Humanities [K]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Translocation of polybrominated diphenyl ethers from field-contaminated soils to an edible plant. | Polybrominated diphenyl ethers (PBDEs), recognised emerging contaminants, widely exist and persist in the environment. Samples were taken from a heavily contaminated farm in Taiwan located near a factory known to regularly use PBDEs. Sweet potato vines (Ipomoea batatas L., a commonly consumed vegetable in Asia) growing... | ['Environmental Monitoring', 'Halogenated Diphenyl Ethers', 'Ipomoea batatas', 'Plants, Edible', 'Soil Pollutants'] | 29,550,555 | [['N06.850.460.350.080', 'N06.850.780.375'], ['D02.355.726.601', 'D02.455.426.559.389.657.654.601'], ['B01.650.940.800.575.912.250.238.500.500'], ['B01.650.510'], ['D27.888.284.756']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Does the type of maltreatment matter? Assessing the individual and combined effects of multiple forms of childhood maltreatment on exclusive breastfeeding behavior. | BACKGROUND: Childhood maltreatment (CM) has been associated with a range of adult health outcomes; however, extant research has focused more on exposure to a single form of abuse rather than multiple forms. Moreover, very few studies have specifically investigated the impact of CM on exclusive breastfeeding (EBF) outco... | ['Adolescent', 'Adult', 'Adult Survivors of Child Abuse', 'Bangladesh', 'Breast Feeding', 'Child', 'Child Abuse', 'Cross-Sectional Studies', 'Depression, Postpartum', 'Female', 'Humans', 'Infant', 'Logistic Models', 'Middle Aged', 'Young Adult'] | 30,391,785 | [['M01.060.057'], ['M01.060.116'], ['M01.135.500', 'M01.860.300.500'], ['Z01.252.245.131'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Spinal epidural vascular malformation presenting in association with a spontaneously resolved acute epidural hematoma. Case report. | A 16-year-old boy developed acute neck pain and severe quadriparesis after mild rotatory movement of his neck. Magnetic resonance imaging revealed a cervical epidural hematoma that resolved spontaneously within a few days. Vertebral angiography demonstrated a small vascular malformation in the upper cervical epidural s... | ['Acute Disease', 'Adolescent', 'Angiography', 'Arteriovenous Malformations', 'Cervical Vertebrae', 'Dura Mater', 'Epidural Space', 'Follow-Up Studies', 'Hematoma, Epidural, Cranial', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Neck Pain', 'Quadriplegia', 'Remission, Spontaneous', 'Vertebral Artery'] | 9,576,263 | [['C23.550.291.125'], ['M01.060.057'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['A02.835.232.834.151'], ['A08.186.566.395'], ['A02.835.232.834.803.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C10.228.14... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Support during childbirth: perception of health care providers and companions chosen by women]. | OBJECTIVE: To understand health care providers' perception on managing laboring women in the presence of a labor companion of their choice, and the labor companion's perception of this experience.METHODS: A qualitative study was conducted based on a controlled randomized clinical trial. Sampling was intentional and det... | ['Adult', 'Attitude of Health Personnel', 'Caregivers', 'Female', 'Humans', 'Infant, Newborn', 'Interviews as Topic', 'Male', 'Middle Aged', 'Parturition', 'Patient Satisfaction', 'Perception', 'Pregnancy', 'Professional-Family Relations', 'Qualitative Research'] | 17,273,633 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['G08.686.784.769.490'], ['F01.100.150.750.625... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Suppression of the negative effect of minor arginine codons on gene expression; preferential usage of minor codons within the first 25 codons of the Escherichia coli genes. | AGA and AGG codons for arginine are the least used codons in Escherichia coli, which are encoded by a rare tRNA, the product of the dnaY gene. We examined the positions of arginine residues encoded by AGA/AGG codons in 678 E. coli proteins. It was found that AGA/AGG codons appear much more frequently within the first 2... | ['Amino Acid Sequence', 'Arginine', 'Base Sequence', 'Codon', 'Escherichia coli', 'Galactosidases', 'Gene Expression', 'Genes, Bacterial', 'Molecular Sequence Data', 'Oligonucleotide Probes', 'Plasmids', 'RNA, Messenger', 'Restriction Mapping', 'Suppression, Genetic', 'beta-Galactosidase'] | 2,109,307 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.450.410'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fate of transplanted bone marrow derived mesenchymal stem cells following spinal cord injury in rats by transplantation routes. | This research was performed to investigate the differences of the transplanted cells' survival and differentiation, and its efficacy according to the delivery routes following spinal cord injury. Allogenic mesenchymal stem cells (MSCs) were transplanted intravenously (IV group) or intralesionally (IL group) at post-inj... | ['Animals', 'Behavior, Animal', 'Bone Marrow Cells', 'Brain-Derived Neurotrophic Factor', 'Cell Differentiation', 'Drug Administration Routes', 'Male', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Nerve Growth Factor', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord Injuries', 'Transplantation, Homo... | 22,690,088 | [['B01.050'], ['F01.145.113'], ['A11.148', 'A15.378.316'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G04.152'], ['E02.319.267'], ['E02.095.147.500.500.625', 'E04.936.225.687.625'], ['A11.329.830.500', 'A11.872.590.500'], ['D12.644.276.860.437', 'D12.776.467.860.437', 'D... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of hepatitis C virus in human sera with beta-lipoprotein. | Hepatitis C virus (HCV)-RNA in sera of patients with viral hepatitis C is supposed to be included, at least partially, into HCV particles. We found that the density of HCV-RNA-carrying material was variable, as determined by sucrose gradient density centrifugation (1.03-1.20 g/cm3). In some of the sera examined HCV-RNA... | ['Acute Disease', 'Centrifugation, Density Gradient', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Lipoproteins, LDL', 'Polymerase Chain Reaction', 'Protein Binding', 'RNA, Viral'] | 1,335,546 | [['C23.550.291.125'], ['E05.181.724.336', 'E05.196.941.336'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.515', 'D12.776.521.550'], ['E05.393.620.500'], ['G02.111.679', 'G03.808']... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute Coronary Syndrome Does Not Have a Negative Impact on Outcomes after Coronary Artery Bypass Grafting in Patients with Left Main Disease. | PURPOSE: Early and long-term outcomes of coronary artery bypass grafting (CABG) in patients with left main disease (LMD) with acute coronary syndrome (ACS) have never been assessed.METHODS: Between September 2004 and April 2012, 459 patients with LMD underwent first-time isolated CABG. Of those, 191 patients had ACS an... | ['Acute Coronary Syndrome', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Coronary Artery Bypass', 'Coronary Artery Bypass, Off-Pump', 'Coronary Artery Disease', 'Disease-Free Survival', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Postopera... | 25,641,028 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of amiloride on the intracellular sodium and potassium content of intact Streptococcus faecalis cells in vitro. | Amiloride at millimolar concentrations caused marked changes in the growth-dependent intracellular balance of Na+ and K+ in Streptococcus faecalis. These results, whether specific to transport processes or resulting from indirect yet unknown mechanisms, constitute the first evidence of an effect of amiloride on bacteri... | ['Amiloride', 'Enterococcus faecalis', 'Hydrogen-Ion Concentration', 'Potassium', 'Sodium'] | 3,089,143 | [['D03.383.679.149'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['G02.300'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of diaphragmatic contraction on the action of the canine parasternal intercostals. | The inspiratory intercostal muscles enhance the force generated by the diaphragm during lung expansion. However, whether the diaphragm also alters the force developed by the inspiratory intercostals is unknown. Two experiments were performed in dogs to answer the question. In the first experiment, external, cranially o... | ['Airway Resistance', 'Animals', 'Diaphragm', 'Dogs', 'Elasticity', 'Intercostal Muscles', 'Muscle Contraction', 'Phrenic Nerve', 'Pleural Cavity', 'Respiration', 'Respiratory Mechanics', 'Ribs', 'Sternum', 'Thoracic Wall'] | 16,782,834 | [['E01.370.386.700.050', 'G09.772.060'], ['B01.050'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.374.590'], ['A02.633.567.900.500'], ['G11.427.494'], ['A08.800.800.720.150.700'], ['A01.923.761.800.650'], ['G09.772.705'], ['G09.772.705.700'], ['A02.835.232.570.500'], ['A02.835.232.570.75... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence of Theory of Mind in the Written Language of Deaf Children. | The link between Theory of Mind (ToM) and literacy is increasingly being recognized in the literature. However, the focus to date has concentrated on the connections between reading and ToM, with an emphasis on the ways in which ToM is implicated in making inferences from text and suggestions that engaging in reading f... | ['Child', 'Cochlear Implants', 'Deafness', 'Female', 'Hearing Aids', 'Humans', 'Language', 'Male', 'Narration', 'Theory of Mind', 'Vocabulary', 'Writing'] | 30,371,796 | [['M01.060.406'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['E07.305.906.500', 'E07.814.458'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['E05.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Isolation and characterization of an anti-complementary protein-bound polysaccharide from the stem barks of Eucommia ulmoides. | EWDS-1, a homogeneous protein-bound polysaccharide, was isolated as an anti-complementary agent from the stem barks of Eucommia ulmoides. EWDS-1 was identified as a branched proteoglycan with average molecular weight about 2,000,000 Da, composed of Gal, Glc and Ara in the ratio of 2.1:1.0:0.9, along with trace of Rha, ... | ['Animals', 'Chromatography, High Pressure Liquid', 'Complement Activation', 'Complement Inactivating Agents', 'Erythrocytes', 'Eucommiaceae', 'Guinea Pigs', 'Humans', 'Methylation', 'Mice', 'Plant Bark', 'Plant Stems', 'Polysaccharides', 'Rabbits', 'Sheep', 'Thrombin Time'] | 18,602,068 | [['B01.050'], ['E05.196.181.400.300'], ['G12.274'], ['D27.505.696.477.656.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.650.940.800.575.912.250.348'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['B01.050.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The antennal motor system of crickets: proctolin in slow and fast motoneurons as revealed by double labelling. | This study describes proctolin-like immunoreactivity (PLI) of identified antennal motoneurons in the brain of adult crickets (Gryllus bimaculatus). The motoneurons were first backfilled with the fluorescent dye Lucifer Yellow and then immunohistochemically labelled with an antibody against proctolin. Altogether 14 of t... | ['Animals', 'Axons', 'Brain', 'Dendrites', 'Densitometry', 'Gryllidae', 'Immune Sera', 'Motor Neurons', 'Movement', 'Muscle Contraction', 'Neuropeptides', 'Oligopeptides', 'Rabbits', 'Sense Organs'] | 8,075,824 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.186.211'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['E05.196.712.224'], ['B01.050.500.131.617.678.410'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females. | Cytochrome P450 (CYP) 3A is an important drug-metabolizing enzyme in humans. Assessing CYP3A activity is necessary for predicting therapeutic outcomes or the potential adverse events of various therapeutics. This study sought to evaluate the distribution of endogenous and exogenous markers reflecting hepatic CYP3A acti... | ['Adult', 'Biomarkers', 'Chromatography, Gas', 'Chromatography, Liquid', 'Cytochrome P-450 CYP3A', 'Female', 'Healthy Volunteers', 'Humans', 'Male', 'Mass Spectrometry', 'Midazolam', 'Middle Aged', 'Young Adult'] | 28,523,515 | [['M01.060.116'], ['D23.101'], ['E05.196.181.349'], ['E05.196.181.400'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.690.708.170.495.500', 'D12.776.422.220.453.860.500'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D03.633.100.079.080.575'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. | Increasing the level of neurotrophins within the central nervous system may have therapeutic efficacy in patients with various neurological diseases. Earlier we have demonstrated that myelin basic protein (MBP)-primed T cells induce the expression of various proinflammatory molecules in glial cells via cell-to-cell con... | ['Animals', 'Brain-Derived Neurotrophic Factor', 'Cell Separation', 'Cyclic AMP Response Element-Binding Protein', 'Female', 'Gemfibrozil', 'Immunologic Factors', 'Integrins', 'Mice', 'Mice, Inbred Strains', 'Microglia', 'Myelin Basic Protein', 'Neuroglia', 'Neurotrophin 3', 'Receptor, Platelet-Derived Growth Factor be... | 17,823,123 | [['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D02.241.081.114.968.500.750', 'D02.241.081.944.509.350', 'D02.355.726.305.750', 'D02.455.426.559.389.657.65... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Toxicity of docetaxel, platine, 5-fluorouracil-based induction chemotherapy for locally advanced head and neck cancer: The importance of nutritional status]. | PURPOSE: The objective of this study was to identify predictive factors of toxicity of docetaxel, platin, 5-fluorouracil (TPF) induction chemotherapy for locally advanced head and neck cancers.PATIENTS AND METHODS: From July 2009 to March 2015, 57 patients treated consecutively with TPF were included retrospectively. T... | ['Adult', 'Age Factors', 'Aged', 'Anemia', 'Antineoplastic Combined Chemotherapy Protocols', 'Cisplatin', 'Docetaxel', 'Enteral Nutrition', 'Febrile Neutropenia', 'Female', 'Fluorouracil', 'Head and Neck Neoplasms', 'Humans', 'Infections', 'Male', 'Middle Aged', 'Nutritional Status', 'Retrospective Studies', 'Thrombocy... | 31,138,520 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C15.378.071'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['E02.421.360', 'E02.642.500.360'], ['C15.378.553.546.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Proposed association between ileoanal j-pouch perforation and rapid consumption of a high-calorie, high-fiber meal: report of two cases. | PURPOSE: We report two cases of ileoanal J-pouch rupture after rapid consumption of high-fiber, high-calorie meals.METHOD: We review the food intake, presentation, laboratory and radiographic data, and course of two patients who developed ileoanal J-pouch perforation after rapid consumption of meals rich in fiber or ca... | ['Adult', 'Colitis, Ulcerative', 'Dietary Fiber', 'Female', 'Humans', 'Male', 'Postprandial Period', 'Proctocolectomy, Restorative'] | 10,910,251 | [['M01.060.116'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G10.261.700'], ['E04.210.219.620', 'E04.210.895.500']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Paget-Schroetter syndrome associated with FV:Q506 and prothrombin 20210A--a case report. | Effort thrombosis of the axillary-subclavian vein (Paget-Schroetter syndrome) develops usually secondary to heavy arm exertion. An underlying chronic venous compressive anomaly at the thoracic outlet or intimal damage of the axillary vein following forceful hyperabduction, external rotation of the shoulder joint has be... | ['Adult', 'Alleles', 'Anticoagulants', 'Axillary Vein', 'Factor V', 'Humans', 'Male', 'Phlebography', 'Point Mutation', 'Polymerase Chain Reaction', 'Prothrombin', 'Recurrence', 'Subclavian Vein', 'Syndrome', 'Thrombectomy', 'Venous Thrombosis', 'Warfarin'] | 10,451,238 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['D27.505.954.502.119'], ['A07.015.908.077'], ['D12.776.124.125.300', 'D12.776.811.272', 'D23.119.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.060.600', 'E01.370.370.050.600'], ['G05.365.590.675'], ['E05.393.620.500'], ['D08.622.709', 'D12.776.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Trends in Process Analytical Technology: Present State in Bioprocessing. | Process analytical technology (PAT), the regulatory initiative for incorporating quality in pharmaceutical manufacturing, is an area of intense research and interest. If PAT is effectively applied to bioprocesses, this can increase process understanding and control, and mitigate the risk from substandard drug products ... | ['Chemistry Techniques, Analytical', 'Humans', 'Quality Control', 'Technology, Pharmaceutical'] | 28,776,065 | [['E05.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.608'], ['E05.916', 'J01.897.836']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The digital shift: challenges and objectives]. | The strategic roadmap "Acc?l?rer le virage num?rique" presented by the Minister of Health aims to give greater coherence to the development of e-health in France, by developing a clear and shared framework that is likely to strengthen the development of digital uses in health. The Agence nationale d'appui ? la performa... | ['Biomedical Technology', 'France', 'Humans', 'Telemedicine'] | 32,245,553 | [['J01.897.120.050'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800']] | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Efficient kinetic resolution in the asymmetric hydrosilylation of imines of 3-substituted indanones and 4-substituted tetralones. | Kinetic resolution of the N-methyl imines of 3-substituted indanones and 4-substituted tetralones could be accomplished by hydrosilylation with a chiral titanocene catalyst. N-Methyl imines of 4-substituted tetralones were resolved to yield, after hydrolysis of the unreacted starting materials, ketones with high ee's a... | ['Imines', 'Ketones', 'Kinetics', 'N-Acetylneuraminic Acid', 'Sertraline', 'Spectrum Analysis', 'Stereoisomerism'] | 10,814,009 | [['D02.491'], ['D02.522'], ['G01.374.661', 'G02.111.490'], ['D02.241.081.844.562.668.050', 'D02.241.511.902.562.668.050', 'D09.067.687.668.030', 'D09.811.589.668.030'], ['D02.092.705.800', 'D02.455.426.559.847.638.845.800', 'D04.615.638.845.800'], ['E05.196.867'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of a Novel Medicolegal Death Investigator-Based Suicide Surveillance System to the National Violent Death Reporting System. | The abundance of actionable information available in a medicolegal suicide investigation is often inaccessible and underutilized in public health to the detriment of prevention efforts. Epidemiologists obtained the Washington County subset of the Oregon Violent Death Reporting System (OR-VDRS). To determine if addition... | ['Data Collection', 'Databases, Factual', 'Humans', 'Information Storage and Retrieval', 'Population Surveillance', 'Risk Factors', 'Suicide', 'United States', 'Violence', 'Wounds and Injuries'] | 31,166,200 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Ochratoxin A mediates MAPK activation, modulates IL-2 and TNF-á mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells. | Ochratoxin A (OTA) is a natural fungal secondary metabolite that contaminates food and animal feed. Human exposure and involvement of this mycotoxin in several pathologies have been demonstrated worldwide. We investigated OTA immunotoxicity on H9 cells, a human cutaneous CD4+ T lymphoma cell line. Cells were treated wi... | ['Apoptosis', 'Autocrine Communication', 'Caspase 3', 'Caspase 8', 'Cell Line, Tumor', 'Cell Shape', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Enzyme Activation', 'Gene Expression Regulation', 'Humans', 'Inhibitor of Apoptosis Proteins', 'Interleukin-2', 'Membrane Potential, Mitochondrial', 'Mitochondria', ... | 27,193,732 | [['G04.146.954.035'], ['G04.085.100'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126.550.800', 'D08.811.277.656.300.200.126.550.800', 'D12.644.360.024.285.037', 'D12.644.360.075.405.550.800', 'D... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cognitive abilities, androgen levels, and body mass index in 5-year-old children. | This study explores the potential relationship between a series of cognitive abilities and testosterone, dehydroepiandrosterone (DHEA), androstenedione, and body mass index (BMI) measurements in 5-year-old children. 60 boys and 69 girls were administered a test (K-BIT) which provided measurements of fluid intelligence ... | ['Affect', 'Androgens', 'Androstenedione', 'Anthropometry', 'Body Mass Index', 'Child, Preschool', 'Cognition', 'Dehydroepiandrosterone', 'Family', 'Female', 'Humans', 'Intelligence', 'Male', 'Neuropsychological Tests', 'Regression Analysis', 'Sex Characteristics', 'Testosterone'] | 15,878,571 | [['F01.470.047'], ['D27.505.696.399.472.161'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406.448'... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Clinical Features and Cytokine Profile in Myositis Patients with Anti-EJ Autoantibodies Detected by a Novel Immunoprecipitation Assay. | Objective: This study aimed to clarify the clinical features, the serum level of autoantibodies, and cytokine of myositis patients with anti-EJ antibody, which targets glycyl tRNA-synthetase (GlyRS).Methods: Sera of 236 Chinese patients with myositis were screened for anti-EJ by a novel immunoprecipitation assay of fla... | ['Adult', 'Autoantibodies', 'Cytokines', 'Female', 'Humans', 'Immunoprecipitation', 'Lung Diseases, Interstitial', 'Male', 'Middle Aged', 'Myositis'] | 31,019,965 | [['M01.060.116'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.150.639', 'E05.478.605'], ['C08.381.483'], ['M01.060.116.630'], ['C05.651.594', 'C10.668.491.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of c-fgr messenger RNA levels in U937 cells treated with different modulating agents. | The U937 cell line was used to investigate the induction of messenger RNA (mRNA) for the c-fgr mRNA tyrosine kinase proto-oncogene in cells of the monocyte-macrophage lineage. U937 cells were exposed to tumour necrosis factor-alpha (TNF-alpha), TNF-beta and transforming growth factor-alpha (TGF-alpha), alone and in com... | ['Animals', 'Calcitriol', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'Lymphotoxin-alpha', 'Macrophages', 'Monocytes', 'Proto-Oncogene Proteins', 'RNA, Messenger', 'Tetradecanoylphorbol Acetate', 'Transforming Growth Factor alpha', 'Tumor Cells, Cultured', 'Tumor Necrosis Factor-alpha', 'src-Family Kinases'] | 1,628,903 | [['B01.050'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D12.644.276.374.480.438', 'D12.644.276.374.750.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Challenging Management of Double Vision After Functional Endoscopic Sinus Surgery-A Series of 6 Cases. | PURPOSE: To present 6 cases of orbital trauma, diplopia and strabismus after functional endoscopic sinus surgery (FESS).DESIGN: Retrospective observational case series.METHODS: The medical charts of suitable patients were reviewed for information on medical examination, imaging studies, the type of corrective surgery, ... | ['Adolescent', 'Adult', 'Aged', 'Diplopia', 'Eye Injuries', 'Female', 'Humans', 'Male', 'Middle Aged', 'Natural Orifice Endoscopic Surgery', 'Oculomotor Muscles', 'Ophthalmologic Surgical Procedures', 'Orbit', 'Paranasal Sinus Diseases', 'Retrospective Studies', 'Strabismus', 'Tomography, X-Ray Computed'] | 29,604,283 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.597.751.941.339', 'C11.966.339', 'C23.888.592.763.941.339'], ['C10.900.300.284.250', 'C11.297', 'C26.915.300.425.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.388.250.630', 'E04.502.250.630'], ['A02.633.567.700'], ['E... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Can computed tomography in the protocol for renal colic be interpreted by urologists? | OBJECTIVE: To examine the ability of urologists to independently (with no radiology consultation) interpret non-contrast-enhanced spiral computed tomography (CT) in patients with acute renal colic.PATIENTS AND METHODS: One hundred consecutive patients presenting to the emergency department with suspected renal colic an... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Colic', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Observer Variation', 'Sensitivity and Specificity', 'Tomography, Spiral Computed', 'Ureteral Calculi'] | 15,610,116 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C16.614.166'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E05.318.370... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Which solute removal mechanism dominates over others in dialyzers for continuous renal replacement therapy? | Selecting dialyzers is more important for blood purification in critical care because other therapeutic options (especially amount of dialysate) are usually limited. Adsorption is a major mechanism of removing toxic substances from patients in these treatments. Several commercial dialyzers designed for acute blood puri... | ['Dialysis Solutions', 'Hemodiafiltration', 'Humans', 'Ultrafiltration'] | 21,040,419 | [['D26.776.708.322', 'D27.505.954.578.483', 'D27.720.752.483'], ['E02.870.300.200', 'E02.912.800.200', 'E04.292.471.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.292.975', 'E05.196.454.807', 'G01.280.807', 'G02.263.807']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Placental peptides metabolism and maternal factors as predictors of risk of gestational diabetes in pregnant women. A case-control study. | BACKGROUND: Gestational diabetes is a risk factor for perinatal complications; include shoulder dystocia, birth injuries such as bone fractures and nerve palsies. It is associated with later development of type 2 diabetes, the risk of macrosomia and other long-term health effects of infants born to diabetic mothers. Th... | ['Adult', 'Blood Glucose', 'Case-Control Studies', 'Cross-Sectional Studies', 'Diabetes, Gestational', 'Female', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Insulin Resistance', 'Leptin', 'Obesity', 'Overweight', 'Peptides', 'Placenta', 'Pregnancy', 'Risk Factors'] | 28,732,072 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
RB but not R-HCVAD is a feasible induction regimen prior to auto-HCT in frontline MCL: results of SWOG Study S1106. | Aggressive induction chemotherapy followed by autologous haematopoietic stem cell transplant (auto-HCT) is effective for younger patients with mantle cell lymphoma (MCL). However, the optimal induction regimen is widely debated. The Southwestern Oncology Group S1106 trial was designed to assess rituximab plus hyperCVAD... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Bendamustine Hydrochloride', 'Combined Modality Therapy', 'Cyclophosphamide', 'Cytarabine', 'Dexamethasone', 'Disease-Free Survival', 'Doxorubicin', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Lymphoma, Mantle-Cell', ... | 27,992,063 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.241.081.114.625', 'D02.455.526.728.650.103', 'D03.633.100.103.123'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endothelin-1 receptors in rat renal glomeruli. | Renal glomeruli form a dynamic structure capable of regulating the glomerular filtration rate (GFR). To explore possible regulating effects of endothelin-1 (ET-1) upon glomerular functions, the presence of specific ET-1 receptors and the biological actions of ET-1 were studied in isolated rat renal glomeruli. The speci... | ['Animals', 'Binding, Competitive', 'Endothelins', 'In Vitro Techniques', 'Iodine Radioisotopes', 'Kidney Glomerulus', 'Male', 'Peptides', 'Rats', 'Rats, Inbred Strains', 'Receptors, Cell Surface', 'Temperature', 'Time Factors'] | 2,473,296 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['E05.481'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['D12.644'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Three-dimensional fine structure of the biliary tract: scanning electron microscopy of biliary casts. | The three-dimensional structure of the biliary tract was studied by scanning electron microscopy (SEM) of biliary casts. The replica of the biliary tract was successfully prepared by retrograde injection of low viscosity resin into the common bile duct. Bile canaliculi are intricate networks in which hexagonal and pent... | ['Biliary Tract', 'Humans', 'Microscopy, Electron, Scanning'] | 2,338,587 | [['A03.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of smoking urge through imaginal and in vivo procedures: physiological and self-report manifestations. | This experiment assessed reactivity to imaginal and in vivo smoking and control cues. One hundred current smokers were assessed during 2 sessions separated by a 6-hr interval, and half of the participants were abstinent from smoking over this interval. Verbal and physiological reactivity measures were selected based on... | ['Adult', 'Analysis of Variance', 'Cues', 'Female', 'Humans', 'Imagery, Psychotherapy', 'Male', 'Motivation', 'Regression Analysis', 'Smoking', 'Social Facilitation', 'Substance Withdrawal Syndrome'] | 9,103,714 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.249', 'F04.754.462'], ['F01.658', 'F01.752.543.500.750'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['F01.145.805'], ['F01.145... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endovascular treatment of basilar tip aneurysms associated with moyamoya disease. | We report the efficacy and safety of endovascular treatment of basilar tip aneurysms (BTA) in five patients with moyamoya disease. The patients underwent intra-aneurysmal embolisation with detachable platinum coils. Three BTA presented with subarachnoid haemorrhage (SAH); the other two were asymptomatic. In four cases,... | ['Adult', 'Angiography, Digital Subtraction', 'Basilar Artery', 'Embolization, Therapeutic', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Moyamoya Disease', 'Stents', 'Subarachnoid Hemorrhage', 'Treatment Outcome'] | 12,774,181 | [['M01.060.116'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['A07.015.114.106'], ['E02.520.360', 'E02.926.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical equivalence of a novel non-chlorofluorocarbon-containing salbutamol sulfate metered-dose inhaler and a conventional chlorofluorocarbon inhaler in patients with asthma. | BACKGROUND: New formulations of non-chlorofluorocarbon-containing propellants for pressurized metered-dose inhaler delivery systems must be developed in response to the forthcoming ban on chlorofluorocarbon (CFC) production.OBJECTIVE: This study compared the bronchodilator effects of 100, 200, and 300 micrograms (base ... | ['Administration, Inhalation', 'Adolescent', 'Adult', 'Albuterol', 'Asthma', 'Chlorofluorocarbons', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Middle Aged', 'Nebulizers and Vaporizers', 'Therapeutic Equivalency'] | 7,622,763 | [['E02.319.267.050'], ['M01.060.057'], ['M01.060.116'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D02.455.526.439.220', 'D02.455.526.510.140'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the â2-á2 loop of PrPC. | The transmission of infectious prions into different host species requires compatible prion protein (PrP) primary structures, and even one heterologous residue at a pivotal position can block prion infection. Mapping the key amino acid positions that govern cross-species prion conversion has not yet been possible, alth... | ['Amyloid', 'Animals', 'Cell-Free System', 'Mice', 'Mutagenesis, Site-Directed', 'Mutation', 'Neurodegenerative Diseases', 'PrPC Proteins', 'Prion Diseases', 'Prion Proteins', 'Prions', 'Protein Binding', 'Protein Structure, Tertiary', 'Tyrosine'] | 24,596,090 | [['D05.500.049', 'D12.776.049'], ['B01.050'], ['A11.284.835.168'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.420.601.575'], ['G05.365.590'], ['C10.574'], ['D12.776.785.340.500'], ['C01.207.800', 'C10.228.228.800', 'C10.574.843'], ['D12.776.395.550.448.600', 'D12.776.543.484.500.625', 'D12.776.543.550.418.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The combi-targeting concept: evidence for the formation of a novel inhibitor in vivo. | With the purpose of developing drugs that can block multiple targets in tumor cells, molecules termed combi-molecules or TZ-I have been designed to be hydrolyzed in vitro to TZ+I, where TZ is a DNA-damaging species and I is an inhibitor of the epidermal growth factor receptor (EGFR). Using HPLC and liquid chromatograph... | ['Acetylation', 'Animals', 'Cell Proliferation', 'Chromatography, High Pressure Liquid', 'Chromatography, Liquid', 'ErbB Receptors', 'Humans', 'Male', 'Mass Spectrometry', 'Mice', 'Prostatic Neoplasms', 'Quinazolines', 'Triazenes', 'Tumor Cells, Cultured'] | 16,428,934 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.196.181.400.300'], ['E05.196.181.400'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Transformation of the Heart: An Object Relations Perspective. | The author asserts that the closed heart referred to in the Scriptures manifests itself through a defensive false self and an I-It mode of relating. Through an object relations informed treatment, it is proposed that the closed heart may be transformed into an open heart manifested through a real self and I-Thou forms ... | ['Empathy', 'Humans', 'Interpersonal Relations', 'Love', 'Object Attachment', 'Pastoral Care', 'Psychological Theory'] | 26,463,851 | [['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.470.734'], ['F02.739.794.624'], ['F02.784.176.560', 'F02.880.410'], ['F02.739']] | ['Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Macrophages and Galectin 3 Control Bacterial Burden in Acute and Subacute Murine Leptospirosis That Determines Chronic Kidney Fibrosis. | Previous studies have suggested that macrophages may contribute to acute Leptospira dissemination, as well as having a major role in kidney fibrosis. Our aim was to characterize the role of macrophages and galectin 3 (Gal-3) on the survival, clinical course, bacterial burden, interstitial nephritis, and chronic kidney ... | ['Animals', 'Bacterial Load', 'Cells, Cultured', 'Disease Models, Animal', 'Fibrosis', 'Galectin 3', 'Humans', 'Kidney Diseases', 'Leptospira interrogans', 'Leptospirosis', 'Macrophages', 'Mice, Inbred C57BL', 'Rats'] | 30,425,972 | [['B01.050'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.355'], ['D12.776.503.307.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control of long chain fatty acid oxidation in heart mitochondria as studied by spin labeling. | Spin-labeled stearic acid is shown to exhibit the same beta-oxidation kinetics as normal stearic acid. ESR spectra recorded in conditions allowing beta-oxidation indicate that membrane-bound fatty acids can be directly beta-oxidized and that the rate of this reaction depends on the concentration of albumin in the mediu... | ['Albumins', 'Animals', 'Electron Spin Resonance Spectroscopy', 'Female', 'In Vitro Techniques', 'Kinetics', 'Membranes', 'Mitochondria, Muscle', 'Myocardium', 'Oxidation-Reduction', 'Protein Binding', 'Rats', 'Spin Labels', 'Stearic Acids'] | 188,486 | [['D12.776.034'], ['B01.050'], ['E05.196.867.519.274'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['A10.615'], ['A11.284.430.214.190.875.564.627', 'A11.284.835.626.627'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['G02.700', 'G03.295.531'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.992.635.505.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microalbuminuria in patients with acute ischemic stroke. | OBJECTIVE: Microalbuminuria could be detected in patients with acute stroke. However, the association between microalbuminuria and the severity of ischemic stroke has not been systematically investigated. This study aimed to systematically explore the prevalence of microalbuminuria in ischemic stroke patients, and the ... | ['Aged', 'Albuminuria', 'Brain Ischemia', 'Cerebral Infarction', 'Female', 'Humans', 'Ischemia', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'Risk Factors', 'Stroke'] | 30,931,822 | [['M01.060.116.100'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['B01.0... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier. | The effects of exchangeable ions and pH on the efflux of pyruvate from preloaded mitochondria are reported. Efflux obeys first-order kinetics, and the stimulation of efflux by exchangeable ions such as acetoacetate and lactate obeys Michaelis--Menten kinetics. The apparent Km value +/- S.E. for acetoacetate was 0.56 +/... | ['Animals', 'Binding Sites', 'Biological Transport', 'Coumaric Acids', 'Gluconeogenesis', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Ketone Bodies', 'Kinetics', 'Membranes', 'Mitochondria', 'Nitriles', 'Pyruvates', 'Rats'] | 28,726 | [['B01.050'], ['G02.111.570.120'], ['G03.143'], ['D02.241.223.200.210'], ['G02.111.158.500', 'G03.191.500'], ['G02.300'], ['E05.481'], ['D02.522.585'], ['G01.374.661', 'G02.111.490'], ['A10.615'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D02.626'], ['D02.241.755.812'], ['B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developing a new case based computer-aided detection scheme and an adaptive cueing method to improve performance in detecting mammographic lesions. | The purpose of this study is to evaluate a new method to improve performance of computer-aided detection (CAD) schemes of screening mammograms with two approaches. In the first approach, we developed a new case based CAD scheme using a set of optimally selected global mammographic density, texture, spiculation, and str... | ['Algorithms', 'Breast Density', 'Breast Neoplasms', 'Early Detection of Cancer', 'Female', 'Humans', 'Mammography', 'Neural Networks, Computer', 'ROC Curve', 'Radiographic Image Interpretation, Computer-Assisted'] | 27,997,380 | [['G17.035', 'L01.224.050'], ['E01.370.600.115.275', 'G07.100.138'], ['C04.588.180', 'C17.800.090.500'], ['E01.390.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['G17.485', 'L01.224.050.375.605'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Outcomes in Melanoma Patients Treated with BRAF/MEK-Directed Therapy or Immune Checkpoint Inhibition Stratified by Clinical Trial versus Standard of Care. | OBJECTIVES: Since 2011, metastatic melanoma treatment has evolved with commercial approval of BRAF- and MEK-targeted therapy and CTLA-4- and PD-1-blocking antibodies (immune checkpoint inhibitors, ICI). While novel therapies have demonstrated improved prognosis in clinical trials, few studies have examined the evolutio... | ['Antibodies, Monoclonal', 'Antineoplastic Agents', 'Clinical Trials, Phase III as Topic', 'Female', 'Humans', 'Immunotherapy', 'Male', 'Melanoma', 'Middle Aged', 'Mitogen-Activated Protein Kinase Kinases', 'Molecular Targeted Therapy', 'Outcome Assessment, Health Care', 'Prognosis', 'Proto-Oncogene Proteins B-raf', 'S... | 28,601,879 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248'], ['E05.318.372.250.250.220', 'N05.715.360.330.250.250.220', 'N06.850.520.450.250.250.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['C04.557.465.625.650.510', 'C04.557.580.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Exercise-induced asthma in children and oral terbutaline. A dose-response relationship study]. | We wanted to assess the protective effects on exercise-induced asthma as well as the clinical efficacy and safety of increasing doses of a new sustained-release formulation of terbutaline sulphate in 17 asthmatic children aged 6-12 years (mean 9 years). Placebo, 2, 4, and 6 mg terbutaline were given b.i.d. for 14 days ... | ['Administration, Oral', 'Asthma, Exercise-Induced', 'Child', 'Cross-Sectional Studies', 'Delayed-Action Preparations', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Terbutaline'] | 7,985,255 | [['E02.319.267.100'], ['C08.127.108.110', 'C08.674.095.110', 'C20.543.480.680.095.110'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D26.255.210', 'E02.319.300.253'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A phase I study of the HSP90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft-tissue sarcomas. | PURPOSE: Heat shock protein 90 (HSP90) is required for the proper folding, function, and stability of various client proteins, two of which (KIT and PDGFRá) are critical in the pathogenesis and progression of gastrointestinal stromal tumors (GIST). This phase I study investigated the safety and maximum tolerated dose (... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Benzoquinones', 'Female', 'Gastrointestinal Neoplasms', 'Gastrointestinal Stromal Tumors', 'HSP90 Heat-Shock Proteins', 'Humans', 'Lactams, Macrocyclic', 'Male', 'Middle Aged', 'Protein Kinase Inhibitors', 'Sarcoma', 'Treatment Outcome', 'Young Adult'] | 24,045,182 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['D02.806.250'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['C04.557.450.565.370', 'C06.301.371.308', 'C06.405.249.308'], ['D12.776.580.216.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.327', 'D04.345.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Homeostatic intracellular-free Ca2+ is permissive for Rap1-mediated constitutive activation of alpha4 integrins on eosinophils. | Although much progress has been made in understanding the molecular mechanisms underlying agonist-induced "inside-out" activation of integrins, little is known about how basal levels of integrin function are maintained. This is particularly important for nonactivated eosinophils, where intermediate activation of alpha(... | ['Calcium', 'Eosinophils', 'Homeostasis', 'Humans', 'Integrin alpha4', 'Type C Phospholipases', 'Vascular Cell Adhesion Molecule-1', 'rap1 GTP-Binding Proteins'] | 18,390,735 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408.100.450'], ['D08.811.277.352.640.700.700'], ['D12.776.395.550.200.920', 'D12.776.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visualization method for fingerprints on skin by impression on a polyethylene terephthalate (PET) semirigid sheet. | Based on the phenomenon that static electricity attracts dust, a polyethylene terephthalate (PET) semirigid sheet coated with printing ink was used to visualize impressions of fingerprints on the skin of living and dead bodies. Compared with visualization methods for perspiration fingerprints, this method recovers bett... | ['Dermatoglyphics', 'Forensic Medicine', 'Humans', 'Polyethylene Terephthalates', 'Skin'] | 1,386,880 | [['E05.318.740.225.500.375', 'I01.198.780.937.343', 'N04.452.910.099.500'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.728.764', 'D25.720.728.764', 'J01.637.051.720.728.764'], ['A17.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Intranuclear crystal formation in picornavirus-infected cells. | Cells infected with echovirus or poliovirus were incubated at a suboptimal temperature (28 degrees C). When the cells were examined by electron microscopy, not only were crystalline arrays of mature virus particles observed in the cytoplasm but crystals composed of immature virus-like particles were also evident in the... | ['Antigens, Viral', 'Cell Line', 'Cell Nucleus', 'Crystallization', 'Echovirus 6, Human', 'Enterovirus B, Human', 'Poliovirus', 'RNA, Viral', 'Viral Proteins'] | 208,486 | [['D23.050.327'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.196.300', 'G02.171'], ['B04.820.578.750.284.182.225'], ['B04.820.578.750.284.182'], ['B04.820.578.750.284.184.500'], ['D13.444.735.828'], ['D12.776.964']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term outcome of rotational acetabular osteotomy: 145 hips followed for 10-23 years. | We report the long-term outcome of rotational acetabular osteotomy in 145 dysplastic hips of 131 patients after an average follow-up of 13 (10-23) years. The mean age at operation was 28 (11-52) years. The radiographic severity of osteoarthrosis before operation, according to the criteria of the Japanese Orthopaedic As... | ['Adolescent', 'Adult', 'Child', 'Female', 'Follow-Up Studies', 'Hip Dislocation, Congenital', 'Hip Joint', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis', 'Osteotomy', 'Radiography', 'Treatment Outcome'] | 9,703,399 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606', 'C0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Understanding failure of obstetric referral to the Cotonou University gynaecology and obstetrics clinic]. | INTRODUCTION: Since 2000, in the context of the Millennium development goals, Benin has reinforced its obstetric referral system in order to reduce maternal mortality. However, structural, sociocultural and economic problems continue to affect this strategy. The Cotonou University gynaecology and obstetrics clinic (CUG... | ['Adolescent', 'Adult', 'Benin', 'Communication', 'Female', 'Humans', 'Maternal Health Services', 'Outpatient Clinics, Hospital', 'Patient Compliance', 'Patient Education as Topic', 'Pregnancy', 'Pregnancy Complications', 'Referral and Consultation', 'Young Adult'] | 29,384,306 | [['M01.060.057'], ['M01.060.116'], ['Z01.058.290.190.200'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.143.620', 'N02.421.800.500'], ['N02.278.035.380', 'N02.278.216.500.968.527', 'N04.452.442.452.422.527'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Morphogenesis and ductal development of the prostatic complex of the guinea pig. | The morphogenesis of glandular architecture of the three lobes of prostate gland of the guinea pig, lateral, dorsal, and coagulating gland was studied from 35 days gestation to 90 postnatal days. Epithelial ductal tubules of various lobes of the gland were microdissected after treatment by collagenase and displayed two... | ['Aging', 'Animals', 'Animals, Newborn', 'Guinea Pigs', 'Male', 'Prostate'] | 8,371,276 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.992.550'], ['A05.360.444.575', 'A10.336.707']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adjuvant chemotherapy of human colorectal adenocarcinoma after growth on mice with congenital thymic dysplasia ("nude"). 2. Tumor remission following treatment with 5-FU and VCR of xenotransplanted primary human colorectal adenocarcinomas. | The poor 5-year survival rate of patients with malignant colorectal tumors calls for clarification of the question as to whether it is advisable to carry out postoperative adjuvant chemotherapy. In the present study a simple "in vivo" test is described with which the sensitivity of individual human adenocarcinomas of t... | ['Adenocarcinoma', 'Animals', 'Drug Therapy, Combination', 'Female', 'Fluorouracil', 'Humans', 'Male', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Neoplasms, Experimental', 'Rectal Neoplasms', 'Sigmoid Neoplasms', 'Transplantation, Heterologous', 'Vincristine'] | 7,400,203 | [['C04.557.470.200.025'], ['B01.050'], ['E02.319.310'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['E05.624'], ['C04.619', 'E05.598.500.496'], ['C04.588.274.476.411.307.790', 'C06.301.37... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disgusted by Sexual Abuse: Exploring the Association Between Disgust Sensitivity and Posttraumatic Stress Symptoms Among Mothers of Sexually Abused Children. | Nonoffending mothers of sexually abused children often exhibit high levels of posttraumatic stress (PTS) symptoms. Emerging evidence suggests that trait-like individual differences in sensitivity to disgust play a role in the development of PTS symptoms. One such individual difference, disgust sensitivity, has not been... | ['Adolescent', 'Child', 'Child Abuse, Sexual', 'Child, Preschool', 'Emotions', 'Female', 'Humans', 'Linear Models', 'Male', 'Mothers', 'Risk Factors', 'Socioeconomic Factors', 'Stress Disorders, Post-Traumatic', 'Surveys and Questionnaires'] | 27,214,793 | [['M01.060.057'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['M01.060.406.448'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.4... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of differential hippocampal damage upon rhythmic and stress-induced corticosterone secretion in the rat. | The effects of dorsal, ventral, and near-total hippocampal lesions upon both rhythmic and stress-induced corticosterone secretion in adult male rats were examined. All hippocampally-damaged, cortically-damaged, and intact rats showed rhythmic corticosterone secretion as measured in 4 blood samples for each animal taken... | ['Animals', 'Brain Mapping', 'Circadian Rhythm', 'Corticosterone', 'Hippocampus', 'Rats', 'Stress, Physiological'] | 1,172,607 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.180.562.190'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.992.635.505.700'], ['G07.775']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mycogenic Selenium Nanoparticles as Potential New Generation Broad Spectrum Antifungal Molecules. | The current challenges of sustainable agricultural development augmented by global climate change have led to the exploration of new technologies like nanotechnology, which has potential in providing novel and improved solutions. Nanotools in the form of nanofertilizers and nanopesticides possess smart delivery mechani... | ['Alternaria', 'Antifungal Agents', 'Capsicum', 'Colletotrichum', 'Lycopersicon esculentum', 'Metal Nanoparticles', 'Nanotechnology', 'Plant Leaves', 'Selenium', 'Trichoderma', 'X-Ray Diffraction'] | 31,466,286 | [['B01.300.381.075'], ['D27.505.954.122.136'], ['B01.650.940.800.575.912.250.908.500.145'], ['B01.300.381.235'], ['B01.650.940.800.575.912.250.908.500.322'], ['J01.637.512.600.500'], ['H01.603', 'J01.897.520.600'], ['A18.024.812'], ['D01.268.185.850', 'D01.578.700'], ['B01.300.381.910'], ['E05.196.309.742', 'E05.196.82... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Invasive pneumococcal disease in Greenland. | INTRODUCTION: The purpose of the present study was to evaluate the incidence and outcome of pneumococcal infections in Greenland with special reference to serotypes.STUDY DESIGN: Retrospective study of invasive pneumococcal infections in Greenland in the period 1996-2002.METHODS: Cases were defined as patients with pos... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Greenland', 'Humans', 'Incidence', 'Infant', 'Inuits', 'Middle Aged', 'Pneumococcal Infections', 'Streptococcus pneumoniae'] | 15,762,021 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.567.403', 'Z01.542.816.124.500', 'Z01.639.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['M01.68... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Semi-interpenetrated, dendritic, dual-responsive nanogels with cytochrome c corona induce controlled apoptosis in HeLa cells. | The use of thermoresponsive nanogels (NGs) allows the controlled release of therapeutic molecules upon a thermal switch. Usually, this strategy involves the use of temperature increase to activate cargo expulsion from shrinking NGs. In this study, poly(N-isopropylacrylamide) (pNIPAM)-based NGs were involved in the rele... | ['Acrylic Resins', 'Apoptosis', 'Chemistry, Pharmaceutical', 'Cytochromes c', 'Delayed-Action Preparations', 'Dendrimers', 'Drug Carriers', 'Gels', 'Glycerol', 'HeLa Cells', 'Heptanoic Acids', 'Humans', 'Hydrogen-Ion Concentration', 'Nanoparticles', 'Phase Transition', 'Polymers', 'Temperature'] | 29,932,977 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['G04.146.954.035'], ['H01.158.703.007', 'H01.181.466'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['D26.255.210', 'E02.319.300.253'], ['D05.750.327', 'E02.319.300.380.200', 'J01.637.512.600.200'], ['D26.255.260', 'E02.319.300.380'], ... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Outcome of conventional IVF and ICSI on sibling oocytes in the case of isolated teratozoospermia. | PURPOSE: To reevaluate the effect of isolated teratozoospermia on IVF and determine if there was any therapeutic benefit to isolated teratozoospermia by ICSI, since there are no widely accepted criteria for the treatment technique about isolated teratozoospermia.METHODS: A total of 441 couples with >20 million and prog... | ['Abortion, Spontaneous', 'Case-Control Studies', 'Cell Shape', 'Embryo Implantation', 'Embryo, Mammalian', 'Embryonic Development', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Male', 'Male', 'Oocyte Retrieval', 'Oocytes', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Rate', 'Reproducibility of Results',... | 22,733,316 | [['C13.703.039', 'G08.686.784.769.496.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G04.320'], ['G08.686.784.170.104.500'], ['A16.254'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C1... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Bent dsDNA with defined geometric characteristics in terms of complexes of bridged oligonucleotides]. | An opportunity of designing nontypical double-stranded DNA structures containing nonnatural inserts in a regular nucleotide DNA sequence has been investigated. The looped nucleotide inserts on the basis of adenylates and thymidilates, and nonnucleotide inserts on the basis of phosphodiesters of diethyleneglycol, 1,10-d... | ['DNA', 'Electrophoresis, Polyacrylamide Gel', 'Ethylene Glycols', 'Fatty Alcohols', 'Furans', 'Nucleic Acid Conformation', 'Nucleic Acid Denaturation', 'Nucleic Acid Heteroduplexes', 'Oligonucleotides', 'Organophosphates'] | 19,621,054 | [['D13.444.308'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.033.455.250'], ['D02.033.415', 'D10.289'], ['D03.383.312'], ['G02.111.570.820.486', 'G05.360.580'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['D13.444.500'], ['D13.695.578.424'], ['D02.705.400']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An evaluation of simulated clinical practice for adult branch students. | AIM: To evaluate simulation strategies used for adult branch nursing students in one university.METHOD: A questionnaire was used to collect quantitative data and open comments (qualitative data). The evaluation was completed by 45 of a group of 60 second-year diploma nursing students.FINDINGS: There was widespread agre... | ['Adult', 'Attitude of Health Personnel', 'Chest Pain', 'Clinical Competence', 'Education, Nursing, Baccalaureate', 'Feedback, Psychological', 'Humans', 'Manikins', 'Nursing Assessment', 'Nursing Education Research', 'Nursing Methodology Research', 'Nursing Theory', 'Program Evaluation', 'Qualitative Research', 'Self E... | 19,263,960 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['C23.888.592.612.233'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.462.316'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129.400', 'L01.178.820.090.545.129.400'], ['N04.590.233.508.480'], ['H... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Tec... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
In-vitro activity of quinolones and macrolides against mycobacteria. | The activities of eight quinolones (ciprofloxacin, clinafloxacin, levofloxacin, ofloxacin, A-80556, sparfloxacin, temafloxacin and tosufloxacin) and three macrolides (azithromycin, clarithromycin and erythromycin) against 98 clinical isolates of Mycobacterium tuberculosis and 120 isolates of five different atypical myc... | ['4-Quinolones', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Drug Resistance, Multiple', 'Humans', 'Macrolides', 'Microbial Sensitivity Tests', 'Mycobacterium', 'Mycobacterium avium Complex', 'Mycobacterium tuberculosis', 'Nontuberculous Mycobacteria'] | 7,829,409 | [['D03.633.100.810.835.830'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['G07.690.773.984.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.510.024.962.500', 'B03.510.460.400.410.552.552... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MOV10 interacts with Enterovirus 71 genomic 5'UTR and modulates viral replication. | As a cytoplasmic parasite, RNA virus develops sophisticated mechanisms to counter host defense and utilize host proteins to facilitate its replication. Here we found Moloney leukemia virus 10 (MOV10), a highly conserved cellular protein belonging to SF1 helicase family, played critical roles in EV71 infection. Silencin... | ["5' Untranslated Regions", 'ELAV-Like Protein 1', 'Enterovirus A, Human', 'Gene Silencing', 'Genome, Viral', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'Internal Ribosome Entry Sites', 'Microscopy, Fluorescence', 'Protein Binding', 'Protein Domains', 'RNA', 'RNA Helicases', 'RNA, Viral', 'Virus Replication'] | 27,666,477 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['D12.776.157.725.813.500.250', 'D12.776.664.962.813.500.250'], ['B04.820.578.750.284.180'], ['G05.308.203.374'], ['G05.360.340.358.840'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.210.190.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Azobenzene-aminoglycoside: Self-assembled smart amphiphilic nanostructures for drug delivery. | Here, we have designed and synthesized a novel cationic amphiphilic stimuli-responsive azobenzene-aminoglycoside (a small molecule) conjugate, Azo-AG 5, and characterized it by UV and FTIR. Light responsive nature of Azo-AG 5 was assessed under UV-vis light. Self- assembly of Azo-AG 5 in aqueous solutions into nanostru... | ['Aminoglycosides', 'Azo Compounds', 'Cell Survival', 'DNA', 'Delayed-Action Preparations', 'Drug Carriers', 'Drug Delivery Systems', 'HeLa Cells', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'NADH, NADPH Oxidoreductases', 'Nanostructures', 'Photochemical Processes'] | 26,255,160 | [['D09.408.051'], ['D02.172'], ['G04.346'], ['D13.444.308'], ['D26.255.210', 'E02.319.300.253'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['D08.811.682.608'], ['J01.637.512'], ['G02.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism. | The oxidant peroxynitrite/peroxynitrous acid (ONOO-/ONOOH) is generated at sites of inflammation via reaction of O2.- with .NO. Previous studies have shown that these species can oxidize cellular targets, but few data are available on damage to extracellular matrix and its components, despite evidence for matrix modifi... | ['Chondroitin', 'Electron Spin Resonance Spectroscopy', 'Extracellular Matrix', 'Glycosaminoglycans', 'Heparin', 'Hyaluronic Acid', 'Hydroxyl Radical', 'Kinetics', 'Peroxynitrous Acid', 'Solutions'] | 17,382,208 | [['D09.698.373.200'], ['E05.196.867.519.274'], ['A11.284.295.310'], ['D09.698.373'], ['D09.698.373.400'], ['D09.698.373.475'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['G01.374.661', 'G02.111.490'], ['D01.625.600.800', 'D01.625.700.750'], ['D26.776']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular phylogenetics of ponerine ants (Hymenoptera: Formicidae: Ponerinae). | Recent molecular phylogenetic studies of ants (Hymenoptera: Formicidae) have revolutionized our understanding of how these ecologically dominant organisms diversified, but detailed phylogenies are lacking for most major ant subfamilies. I report the results of the first detailed phylogenetic study of the ant subfamily ... | ['Animals', 'Ants', 'Databases, Genetic', 'Ecosystem', 'Phylogeny', 'Phylogeography', 'Social Behavior', 'Species Specificity', 'Time Factors'] | 26,295,106 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G16.500.275.157', 'N06.230.124'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['H01.158.273.343.335.500', 'H01.277.500.589'], ['F01.145.813'], ['G16.824'], ['G01.910.857']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Alcohol intoxication may exacerbate the effects of blunt cranial trauma through changes in brain free magnesium levels. | Moderate to high levels of alcohol decrease brain intracellular free magnesium concentration, a factor known to be critical in brain injury. Phosphorus magnetic resonance spectroscopy was used to examine changes to brain free magnesium concentration after blunt cranial trauma in alcohol-intoxicated rats. Rats exposed a... | ['Adult', 'Alcoholic Intoxication', 'Animals', 'Brain', 'Central Nervous System Depressants', 'Ethanol', 'Forensic Pathology', 'Forensic Toxicology', 'Head Injuries, Closed', 'Humans', 'Magnesium', 'Male', 'Models, Animal', 'Rats', 'Rats, Sprague-Dawley'] | 22,372,670 | [['M01.060.116'], ['C25.775.100.175', 'F03.900.100.300'], ['B01.050'], ['A08.186.211'], ['D27.505.696.277', 'D27.505.954.427.210'], ['D02.033.375'], ['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['H01.158.891.424', 'H02.884.424', 'I01.198.780.968'], ['C10.900.300.350', 'C26.915.300.450', 'C26.974.382']... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
New Genome-Wide Methods for Elucidation of Candidate Copy Number Variations (CNVs) Contributing to Alzheimer's Disease Heritability. | The complexity of human genetic variation has been extended by the observation of abundant and widespread variation in the copy number of submicroscopic DNA segments. The discovery of this novel level of genome organization opened new possibilities concerning the genetic variation that may confer susceptibility to or c... | ['Alzheimer Disease', 'Comparative Genomic Hybridization', 'DNA Copy Number Variations', 'Genetic Predisposition to Disease', 'Genome-Wide Association Study', 'Humans', 'Oligonucleotide Array Sequence Analysis', 'Polymorphism, Single Nucleotide'] | 26,235,076 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['G05.365.795.297.500'], ['C23.550.291.687.500', 'G05.380.355'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Some aspects of vitamin E related to humans and breast cancer prevention. | The biological activities of vitamin E are related to the cellular functions and presence of sufficient tissue concentrations of this micronutrient. Most of the stored vitamin E is in the adipose tissue where it appears to be distributed equally. The breast adipose tissue has similar vitamin E concentrations as other p... | ['Adipose Tissue', 'Administration, Oral', 'Adult', 'Aged', 'Breast', 'Breast Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Milk, Human', 'Pilot Projects', 'Tissue Distribution', 'Vitamin E'] | 7,725,956 | [['A10.165.114'], ['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300.350.525.500', 'J02.200.700.500', 'J02.500.350.525.500'], ... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Comparison of serology and isolates for the identification of infecting leptospiral serogroups in Hawaii, 1979-1998. | Laboratory confirmation of leptospirosis is usually accomplished serologically, without isolates, using the microscopic agglutination test (MAT). However, optimal performance of the MAT is dependent on the knowledge of enzootic serogroups and serovars so that an appropriate MAT antigen testing battery can be establishe... | ['Agglutination Tests', 'Humans', 'Leptospira', 'Leptospirosis', 'Reproducibility of Results', 'Serotyping'] | 12,828,547 | [['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.400.425.475.475', 'B03.851.475.475'], ['C01.150.252.400.794.511'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E01.370.225.812.742', 'E01.370.225... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Placenta growth factor, PLGF, influences the motility of lung cancer cells, the role of Rho associated kinase, Rock1. | Placenta growth factor (PlGF) is a member of the VEGF family and has been implicated in the aggressive capacity of solid tumours, partly via its impact on angiogenesis. The present study determined the direct biological function of endogenous PlGF in lung cancer cells. From the human non-small cell lung cancer cell lin... | ['Cell Adhesion', 'Cell Line, Tumor', 'Cell Survival', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Placenta Growth Factor', 'Pregnancy Proteins', 'RNA, Catalytic', 'Transgenes', 'rho-Associated Kinases'] | 18,615,591 | [['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['D12.644.276.100.800.100', 'D12.776.780.551'], ['D12.776.780'], ['D08.811.797', 'D13.444.735.790.199'], ['G05.360.340.024.340.825']... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The generation of interleukin-2-dependent suppressor T-cells from patients with systemic metastasis of gastric carcinoma and the phenotypic characterization of the cells defined by monoclonal antibodies. | Suppressor cells, which might be activated in patients with gastric carcinoma, were successfully enriched by the use of interleukin-2 (IL-2) prepared from human tonsils and spleens. That is, peripheral blood lymphocytes cultured for 3 or 4 weeks with IL-2 strongly inhibited the patient's own lymphocyte-proliferative re... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Cell Separation', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Interleukin-2', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Phenotype', 'Stomach Neoplasms', 'T-Lymphocytes', 'T-Lymphocytes, Regulatory'] | 2,931,172 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Aza-crown-ether-appended xanthene: selective ratiometric fluorescent probe for silver(I) ion based on arene-metal ion interaction. | In this Communication, we report on the development of a ratiometric fluorescent probe for silver(I) ions (Ag(I)) based on an arene-metal ion interaction. The probe selectively senses Ag(I) among various metal ions with a large-emission red shift under aqueous conditions, enabling the selective ratiometric detection of... | ['Aza Compounds', 'Crown Ethers', 'Crystallography, X-Ray', 'Fluorescent Dyes', 'Silver', 'Xanthenes'] | 25,007,117 | [['D02.145'], ['D02.355.291.308', 'D04.345.051.500', 'D04.345.241.308'], ['E05.196.309.742.225'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['D03.633.300.953']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma monocyte chemotactic protein-1 levels at 24 hours are a biomarker of primary graft dysfunction after lung transplantation. | Monocyte chemotactic protein-1 (MCP-1), also known as "chemokine ligand 2" (CCL2), is a monocyte-attracting chemokine produced in lung epithelial cells. We previously reported an association of increased levels of plasma MCP-1 with primary graft dysfunction (PGD) after lung transplantation in a nested case-control stud... | ['Adult', 'Biomarkers', 'Chemokine CCL2', 'Cohort Studies', 'Female', 'Humans', 'Lung Transplantation', 'Male', 'Middle Aged', 'Odds Ratio', 'Primary Graft Dysfunction', 'Prospective Studies', 'Respiration, Artificial', 'Time Factors'] | 22,989,614 | [['M01.060.116'], ['D23.101'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of atypical features on the quality of prophylactic effectiveness of long-term lithium treatment in bipolar disorders. | OBJECTIVES: There is still debate about whether the quality of long-term efficacy of lithium in patients with bipolar disorders is influenced by atypical features. Extended Cox regression models allow for the use of all follow-up data on diseases with multiple episodes. The aim of the present analysis was to apply the ... | ['Antimanic Agents', 'Bipolar Disorder', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Lithium', 'Long-Term Care', 'Male', 'Multicenter Studies as Topic', 'Patient Readmission', 'Psychiatric Status Rating Scales', 'Regression Analysis', 'Secondary Prevention', 'Treatment Outcome'] | 20,636,636 | [['D27.505.696.277.950.025', 'D27.505.954.427.210.950.025', 'D27.505.954.427.700.872.025'], ['F03.084.500'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.52... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biologic mechanisms for the regulation of normal human keratinocyte proliferation and differentiation. | Normal human keratinocytes can be grown in serum-free medium, and the integrated control of their proliferation and differentiation can be modulated experimentally. The growth of cultured human keratinocytes can also be specifically arrested at either reversible or irreversible growth arrest states. Reversible growth a... | ['Antibodies, Monoclonal', 'Cell Cycle', 'Cell Differentiation', 'Cell Division', 'Cells, Cultured', 'Clone Cells', 'Epidermal Cells', 'Fluorescent Antibody Technique', 'Humans', 'Keratins', 'Reference Values'] | 2,451,428 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.144'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['A11.251.353'], ['A11.409'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrasound measurements of overlying soft tissue thickness at four skeletal sites suitable for in vivo x-ray fluorescence. | Due to signal attenuation in overlying soft tissue, development of x-ray fluorescence systems to measure low atomic number elements, such as strontium, in human bone required a search for a skeletal site with thin overlying tissue. This paper reports ultrasound measurements of overlying tissue on 10 subjects, at four a... | ['Adult', 'Aged', 'Anthropometry', 'Body Mass Index', 'Bone and Bones', 'Connective Tissue', 'Female', 'Fingers', 'Forehead', 'Heel', 'Humans', 'Male', 'Middle Aged', 'Reference Values', 'Spectrometry, X-Ray Emission', 'Statistics as Topic', 'Tibia', 'Ultrasonography'] | 12,462,736 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A02.835.232', 'A10.165.265'], ['A10.165'], ['A01.378.800.667.430'], ['A01.456.505.580'], ['A01.378.610.250.510'], ['B01.050.150.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
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