Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The electrophoresis of histones in polyacrylamide gel and their quantitative determination. | 1. A new method has been devised for the separation of the histone fractions of calf thymus by electrophoresis in polyacrylamide gel at pH2.4. 2. The fractions have been characterized by their relative mobilities with respect to a marker protein, bovine plasma albumin. 3. A method has been developed for the quantitativ... | ['Acrylic Resins', 'Animals', 'Cattle', 'Electrophoresis', 'Gels', 'Histones', 'In Vitro Techniques', 'Thymus Gland'] | 6,035,526 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.401', 'E05.301.300'], ['D20.280.320', 'D26.255.165.320'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['E05.481'], ['A10.549.750', 'A15.382.520.604.750']... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study. | In chronic lymphocytic leukemia (CLL) the level of minimal residual disease (MRD) after therapy is an independent predictor of outcome. Given the increasing number of new agents being explored for CLL therapy, using MRD as a surrogate could greatly reduce the time necessary to assess their efficacy. In this European Re... | ['Adolescent', 'Adult', 'Antigens, CD', 'Combined Modality Therapy', 'Europe', 'Female', 'Flow Cytometry', 'Follow-Up Studies', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Immunophenotyping', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Neoplasm Staging', 'Neoplasm, Residual', 'Prognosis', 'Young Adult'] | 26,639,181 | [['M01.060.057'], ['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E02.186'], ['Z01.542'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['E05.318.372.500.750.249', 'N05.715.360.330... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The value of basic investigations in the diagnosis of impotence. | 172 patients with impotence symptoms were investigated by SBBBV-test, orthostatic blood pressure, Doppler examination of the superficial and deep penile arteries, penile-brachial index, visual sexual stimulation, papaverin test, and measurement of bulbocavernous reflex latency time. Visual sexual stimulation and papave... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Pressure', 'Erectile Dysfunction', 'Humans', 'Male', 'Middle Aged', 'Papaverine', 'Parasympathetic Nervous System', 'Penile Erection', 'Penis', 'Reflex'] | 3,445,122 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C12.294.644.486', 'F03.835.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.098.666', 'D03.132.577.750', 'D03.633.100.531.085.666'], ['A08.800.050.600'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Indications for endoscopic Nd-YAG laser surgery in the trachea and bronchus. | Nd-YAG laser surgery via the fiberoptic bronchoscope can vaporize lesions causing airway obstruction or stenosis located from the trachea to segmental bronchi with minimized danger of bleeding, and improve ventilatory disturbances. 35 lesions in the trachea and bronchus consisting of 27 malignant lesions and 8 benign l... | ['Adult', 'Aged', 'Airway Obstruction', 'Bronchi', 'Bronchial Neoplasms', 'Endoscopy', 'Female', 'Humans', 'Laser Therapy', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Trachea', 'Tracheal Neoplasms', 'Tracheal Stenosis'] | 6,628,339 | [['M01.060.116'], ['M01.060.116.100'], ['C08.618.846.185'], ['A04.411.125'], ['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.11... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells. | Phosphorylation and dephosphorylation of the retinoblastoma protein, pRB, play a role in the control of cell cycle progression and expression of differentiation in eukaryotic cells. The regulation of pRB level and phosphorylation state was investigated during the induction of differentiation of murine erythroleukemia c... | ['Acetamides', 'Animals', 'Cell Differentiation', 'Cell Division', 'Dexamethasone', 'Erythroid Precursor Cells', 'Gene Expression Regulation, Leukemic', 'Genes, Retinoblastoma', 'Interphase', 'Leukemia, Erythroblastic, Acute', 'Mice', 'Neoplasm Proteins', 'Neoplastic Stem Cells', 'Phosphorylation', 'Protein Processing,... | 1,419,904 | [['D02.065.064', 'D02.241.081.018.110'], ['B01.050'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['A11.148.378.590.837.250', 'A11.443.240.497', 'A11.872.378.590.817.250', 'A15.378.316.378.590.837.250'], ['G05.308.370.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of x-rays on the sensitivity of cells of the murine NKLy tumor to the membrane toxic effect of natural killers]. | A study of membrane toxicity of allogenic splenocytes with regard to irradiated mouse NKLy lymphosarcoma cells (tested by the release of 3H-uridine label from target cells in the presence of exogenous RNAses) has displayed an insignificant increase, as compared with the control, in the membrane toxicity with radiation ... | ['Animals', 'Cytotoxicity, Immunologic', 'Killer Cells, Natural', 'Mice', 'Neoplasms, Experimental'] | 3,423,232 | [['B01.050'], ['G12.287'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.619', 'E05.598.500.496']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The outcome of chronic dialysis in infants and toddlers--advantages and drawbacks of haemodialysis. | BACKGROUND: Improvements in dialysis technology allow replacement therapy for even the youngest of children with end stage renal disease. Nevertheless, the cumulative experience in this age group is limited.METHODS: We compared the outcome of 20 children who initiated chronic dialysis before the age of 1 year (weight 4... | ['Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Kidney Failure, Chronic', 'Outcome Assessment, Health Care', 'Renal Dialysis'] | 18,065,806 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E02.870.300', 'E02.912.800']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Zooprophylaxis: impact of breeding rabbits around houses on reducing the indoor abundance of Phlebotomus papatasi. | Zooprophylaxis is the use of animals to deviate vectors from humans. The indoor abundance of Phlebotomus papatasi in houses with rabbit holes in the peridomestic areas are significantly lower than the indoor abundance in houses without rabbit holes in their peridomestic areas. Introduction of rabbits in artificial unde... | ['Animal Husbandry', 'Animals', 'Feeding Behavior', 'Housing', 'Humans', 'Leishmania major', 'Leishmaniasis, Cutaneous', 'Pest Control, Biological', 'Phlebotomus', 'Rabbits', 'Time Factors', 'Tunisia'] | 18,627,242 | [['J01.040.090'], ['B01.050'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.268.475.868.488.405'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.813.400', 'C17.800... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Ultracytochemical localization of guanylate cyclase in the oviduct of estrogen-stimulated rat. | Many reports have indicated that estrogens increase uterine guanosine 3',5'-cyclic monophosphate (cGMP) levels via increasing the activity of guanylate cyclase. In the present study, guanylate cyclase activity was studied cytochemically in the oviduct of immature rats 24 hours after one or two doses (20 micrograms/kg, ... | ['Animals', 'Cell Membrane', 'Diethylstilbestrol', 'Endothelium', 'Epithelium', 'Fallopian Tubes', 'Female', 'Guanylate Cyclase', 'Microscopy, Electron', 'Muscle, Smooth', 'Rats', 'Rats, Inbred Strains', 'Stimulation, Chemical'] | 6,132,563 | [['B01.050'], ['A11.284.149'], ['D02.455.426.559.389.150.700.725.500'], ['A10.272.491'], ['A10.272'], ['A05.360.319.114.373', 'A13.706.500'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['E01.370.350.515.402', 'E05.595.402'], ['A02.633.570', 'A10.690.467'], ['B01.050.150.900.649.313.992.635.505.700']... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Streptococcus pneumoniae isolates relatively insensitive to penicillin G recovered from patients in Switzerland. | The sensitivity to penicillin G of pneumococci isolated in Switzerland has been determined by the quantitative tube dilution method. 3 out of 100 strains were relatively insensitive to this antibiotic (minimum inhibitory concentration greater than 0.1 microgram/ml), thus confirming observations already made in other co... | ['Culture Media', 'Penicillin G', 'Penicillin Resistance', 'Streptococcus pneumoniae', 'Switzerland'] | 25,749 | [['D27.720.470.305', 'E07.206'], ['D02.065.589.099.750.750', 'D02.886.108.750.750', 'D03.633.100.300.750.750'], ['G06.099.225.500.600', 'G06.225.347.500.600', 'G07.690.773.984.269.347.500.600'], ['B03.353.750.737.872.550', 'B03.510.400.800.872.550', 'B03.510.550.737.872.550'], ['Z01.542.883']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Influence on macrophage functions as a possible basis of immunomodification by polyanions. | The effects of the polyanions, carrageenan, dextran sulphate, polyanetholesulphonate and suramin, on macrophage functions and on the complement system were studied. The function of phagosomes and lysosomes in vitro was inhibited by all polyanions but carrageenan whereas phagocytosis in vitro was enhanced by small doses... | ['Adjuvants, Immunologic', 'Animals', 'Carbon', 'Carrageenan', 'Complement System Proteins', 'Dextrans', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'Polyanetholesulfonate', 'Suramin'] | 6,164,336 | [['D27.505.696.477.067'], ['B01.050'], ['D01.268.150'], ['D09.698.152'], ['D12.776.124.486.274'], ['D05.750.078.562.272', 'D09.698.365.272'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The effectiveness of commonly used lifting assessment methods to identify industrial jobs associated with elevated risk of low-back disorders. | Low-back disorders (LBD) continue to be the most costly and common musculoskeletal problem facing society today. Investigators have developed tools or measures that are intended to identify jobs that will probably be associated with an elevated risk of low-back disorders. However, an important and not widely discussed ... | ['Databases, Factual', 'Humans', 'Lifting', 'Low Back Pain', 'National Institute for Occupational Safety and Health, U.S.', 'Occupational Diseases', 'Psychophysics', 'Risk Factors', 'Safety Management', 'United States', 'Work Capacity Evaluation'] | 9,973,881 | [['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.669'], ['C23.888.592.612.107.400'], ['I01.409.418.750.600.650.200.520', 'N03.540.348.500.500.600.650.225.520'], ['C24'], ['E01.370.685', 'F04.096.753'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05... | ['Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Epidemiology of pulmonary embolism: mortality in a general population. | This report describes the basic epidemiologic characteristics of fatal pulmonary embolism as it was recognized in the adult white population of Washington County, Maryland, from 1963 to 1975. Demographic and personal characteristics considered are age, sex, marital status, educational level, adequacy of housing, cigare... | ['Adult', 'Aged', 'Death Certificates', 'Female', 'Humans', 'Male', 'Maryland', 'Middle Aged', 'Pulmonary Embolism', 'Smoking', 'Socioeconomic Factors'] | 7,304,579 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.940.350', 'L01.399.250.900.350', 'N04.452.859.264', 'N05.715.360.300.715.315', 'N06.850.520.308.940.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['M01.060.116.630'], ['C08.381.746', 'C14.907.355.350.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Characterization of the â-barrel assembly machine accessory lipoproteins from Borrelia burgdorferi. | BACKGROUND: Like all diderm bacteria studied to date, Borrelia burgdorferi possesses a â-barrel assembly machine (BAM) complex. The bacterial BAM complexes characterized thus far consist of an essential integral outer membrane protein designated BamA and one or more accessory proteins. The accessory proteins are typica... | ['Bacterial Outer Membrane Proteins', 'Borrelia burgdorferi', 'Gene Deletion', 'Lipoproteins', 'Models, Molecular', 'Permeability', 'Protein Binding', 'Protein Conformation', 'Protein Multimerization'] | 25,887,384 | [['D12.776.097.120', 'D12.776.543.100'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D10.532', 'D12.776.521'], ['E05.599.595'], ['G02.723'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['G02.111.694']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Troponin I, troponin T, or creatine kinase-MB to detect perioperative myocardial damage after coronary artery bypass surgery. | STUDY OBJECTIVES: To compare cardiac troponin I (cTnI), cardiac troponin T (cTnT), and creatine kinase MB (CKMB mass) in patients with and without new Q wave on the ECG following coronary artery bypass graft (CABG) surgery.PATIENTS: After ethic committee's approval and informed consent, 82 patients, mean age 63+/-10 ye... | ['Biomarkers', 'Coronary Artery Bypass', 'Coronary Disease', 'Creatine Kinase', 'Electrocardiography', 'Female', 'Fluoroimmunoassay', 'Humans', 'Intraoperative Complications', 'Isoenzymes', 'Male', 'Middle Aged', 'Myocardial Infarction', 'ROC Curve', 'Troponin', 'Troponin I', 'Troponin T'] | 9,726,734 | [['D23.101'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250', 'C14.907.585.250'], ['D08.811.913.696.640.150'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.225.500.607.512.240.655', 'E01.370.225.750.551.512.240.655', 'E05.200.500.607.512.240.655', 'E05.200.750.551.512... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preoperative therapy with pazopanib in high-risk soft tissue sarcoma: a phase II window-of-opportunity study by the German Interdisciplinary Sarcoma Group (GISG-04/NOPASS). | INTRODUCTION: For resectable soft tissue sarcoma (STS), radical surgery, usually combined with radiotherapy, is the mainstay of treatment and the only potentially curative modality. Since surgery is often complicated by large tumour size and extensive tumour vasculature, preoperative treatment strategies with the aim o... | ['Angiogenesis Inhibitors', 'Chemotherapy, Adjuvant', 'Disease-Free Survival', 'Endothelial Progenitor Cells', 'Germany', 'Humans', 'Neoplasm Recurrence, Local', 'Prognosis', 'Pyrimidines', 'Receptors, Vascular Endothelial Growth Factor', 'Risk', 'Sarcoma', 'Sulfonamides'] | 26,739,732 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['E02.186.170', 'E02.319.170'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['A11.148.174', 'A11.436.275.182'], ['Z01.542.315'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Mechanical properties and consequences of stereocilia and extracellular links in vestibular hair bundles. | Although knowledge of the fine structure of vestibular hair bundles is increasing, the mechanical properties and functional significance of those structures remain unclear. In 2004, Bashtanov and colleagues reported the contribution of different extracellular links to bundle stiffness. We simulated Bashtanov's experime... | ['Animals', 'Biomechanical Phenomena', 'Cilia', 'Computer Simulation', 'Hair Cells, Vestibular', 'Models, Biological', 'Turtles'] | 16,428,277 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['A11.284.180.165'], ['L01.224.160'], ['A08.675.650.395', 'A08.675.650.915.750.600.675', 'A08.800.950.750.600.675', 'A09.246.300.909.625.125.340', 'A11.671.650.395', 'A11.671.650.915.750.600.675'], ['E05.599.395'], ['B01.050.150.900.833.848']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Regulatory T cell frequencies are increased in preterm infants with clinical early-onset sepsis. | The predisposition of preterm neonates to invasive infection is, as yet, incompletely understood. Regulatory T cells (Tregs ) are potential candidates for the ontogenetic control of immune activation and tissue damage in preterm infants. It was the aim of our study to characterize lymphocyte subsets and in particular C... | ['Adult', 'Amnion', 'Chorioamnionitis', 'Female', 'Forkhead Transcription Factors', 'Gestational Age', 'Humans', 'Immune Tolerance', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Lymphocyte Subsets', 'Pregnancy', 'Sepsis', 'T-Lymphocytes, Regulatory'] | 27,163,159 | [['M01.060.116'], ['A10.615.284.277', 'A16.254.750.277'], ['C13.703.277.030', 'C13.703.420.339.260', 'C13.703.590.268', 'C16.300.030'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'], ['M01.060.703'], ['M01.060... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Decreased carbohydrate tolerance in pregnant patients with an early menarche. | Carbohydrate tolerance was studied in pregnant patients with no personal or family history suggestive of diabetes, but with a menarche before 12 years of age. The mean disappearance rate constant for glucose (k) in the intravenous glucose tolerance test was 1.68 in the group of patients with an early menarche. This val... | ['Blood Glucose', 'Female', 'Glucose Tolerance Test', 'Humans', 'Menarche', 'Parity', 'Prediabetic State', 'Pregnancy', 'Pregnancy in Diabetics'] | 1,163,581 | [['D09.947.875.359.448.500'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760.410', 'G08.686.841.374.410'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['C18.452.394.750.774', 'C19.246.774'], ['G08.686.784.769'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modification by hemochromatosis gene polymorphisms of the association between traffic-related air pollution and cognition in older men: a cohort study. | BACKGROUND: Previous studies found effect modification of associations between traffic-related air pollution and cardiovascular outcomes by polymorphisms in the hemochromatosis gene (HFE). As traffic-related air pollution may impact cognition through effects on cardiovascular health or through mechanisms which may also... | ['Aged', 'Air Pollutants', 'Cognition', 'Cohort Studies', 'Genotype', 'Hemochromatosis Protein', 'Histocompatibility Antigens Class I', 'Humans', 'Male', 'Membrane Proteins', 'Middle Aged', 'Multiplex Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide', 'Soot', 'United States', 'Vehicle Emissions'] | 23,413,885 | [['M01.060.116.100'], ['D27.888.284.101'], ['F02.463.188'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G05.380'], ['D12.776.395.550.489.200', 'D12.776.543.550.439.200', 'D23.050.301.500.100.363', 'D23.050.705.552.100.375'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.30... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Assessing the educational and support needs of nursing staff serving older adults: a case study of a community coalition/university partnership. | Given the expected changes in demography and dependent care ratios, communities are preparing for the needs of older populations. Sometimes, communities form coalitions to address health-care needs. This case study evaluates a coalition/university partnership formed to assess the educational and support needs of nursin... | ['Aged', 'Community-Institutional Relations', 'Delivery of Health Care', 'Geriatrics', 'Health Services Research', 'Humans', 'Needs Assessment', 'Nursing Staff'] | 24,652,930 | [['M01.060.116.100'], ['N04.452.822.210'], ['N04.590.374', 'N05.300'], ['H02.403.355'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['M01.526.485.680', 'N02.360.680']] | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Regulatory effects of heat on normal human melanocyte growth and melanogenesis: comparative study with UVB. | Although energy-rich ultraviolet B (UVB) is considered to be primarily responsible for most of the effects associated with solar radiation, small energy recorded as heat appears to contribute to the biologic effects of solar radiation on the skin. We compared the effects of heat and UVB on normal human melanocyte funct... | ['Cell Division', 'Cells, Cultured', 'Coculture Techniques', 'Dihydroxyphenylalanine', 'Hot Temperature', 'Humans', 'Keratinocytes', 'Melanins', 'Melanocytes', 'Membrane Glycoproteins', 'Monophenol Monooxygenase', 'Oncogene Protein p21(ras)', 'Oxidoreductases', 'Proteins', 'Skin', 'Skin Pigmentation', 'Tumor Suppressor... | 9,620,308 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['E05.481.500.374'], ['D02.092.311.200', 'D02.455.426.559.389.657.166.175.200', 'D12.125.072.050.685.400', 'D12.125.072.050.875.130'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.72... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pressure from the tongue on the teeth in young adults. | Pressure from the tongue on the teeth was measured at the upper and lower central incisors and left first molars in 25 young adults with clinically normal occlusion. Repeated recordings with and without a period for accommodation to the intraoral measuring device, which was connected to an extraoral pressure transducer... | ['Adaptation, Physiological', 'Adult', 'Bicuspid', 'Deglutition', 'Electromyography', 'Equipment Design', 'Female', 'Head', 'Humans', 'Incisor', 'Male', 'Mandible', 'Mastication', 'Maxilla', 'Molar', 'Pressure', 'Reproducibility of Results', 'Tongue', 'Tooth', 'Transducers, Pressure'] | 2,012,318 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['A14.549.167.860.150'], ['G10.261.178'], ['E01.370.405.255', 'E01.370.530.255'], ['E05.320'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860.425'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['G07.203.650.283.500', 'G10.261.330.500'], ... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat. | The effects of glucagon-like peptide 2 (GLP-2) on expression and activity of jejunal multidrug resistance-associated protein 2 (Mrp2; Abcc2) and glutathione transferase (GST) were evaluated. After GLP-2 treatment (12 ìg/100 g b.wt. s.c., every 12 h, for 5 consecutive days), Mrp2 and the á class of GST proteins and thei... | ['ATP-Binding Cassette Transporters', 'Adenylyl Cyclase Inhibitors', 'Animals', 'Blotting, Western', 'Chromatography, High Pressure Liquid', 'Cyclic AMP', 'Dideoxyadenosine', 'Enterocytes', 'Female', 'Fluorescent Antibody Technique', 'Glucagon-Like Peptide 2', 'Glutathione Transferase', 'Intestinal Mucosa', 'Jejunum', ... | 20,719,938 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.519.389.108'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.181.400.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
t-10, c-12 CLA dietary supplementation inhibits atherosclerotic lesion development despite adverse cardiovascular and hepatic metabolic marker profiles. | Animal and human studies have indicated that fatty acids such as the conjugated linoleic acids (CLA) found in milk could potentially alter the risk of developing metabolic disorders including diabetes and cardiovascular disease (CVD). Using susceptible rodent models (apoE(-/-) and LDLr(-/-) mice) we investigated the in... | ['Animals', 'Atherosclerosis', 'Biomarkers', 'Body Weight', 'Dietary Supplements', 'Disease Models, Animal', 'Humans', 'Linoleic Acids, Conjugated', 'Lipid Metabolism', 'Lipoproteins', 'Liver', 'Male', 'Mice', 'Mice, Knockout', 'Organ Size', 'Risk Factors', 'Triglycerides'] | 23,285,120 | [['B01.050'], ['C14.907.137.126.307'], ['D23.101'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.203.300.456', 'J02.500.456'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.251.355.343.5... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors. | Starting from the phase II clinical FGFR inhibitor lucitanib (2), we conducted a medicinal chemistry approach by opening the central quinoline skeleton coupled with a scaffold hopping process thus leading to a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives. Compound 25a was identified... | ['Animals', 'Antineoplastic Agents', 'Benzamides', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Drug Design', 'Drug Screening Assays, Antitumor', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Nude', 'Molecular Structure', 'Neoplasms, Experimental', 'Pyridines', 'Rats', 'Rats, Sprague-Dawl... | 29,775,937 | [['B01.050'], ['D27.505.954.248'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E01.370.225.500.388', 'E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Glomus tumor of uncertain malignant potential on the forehead. | Malignant glomus tumors (GTs) are rare, and diagnosis requires consideration of specific histologic criteria. Glomus tumors that do not fulfill the histologic criteria for malignancy but show at least 1 feature other than nuclear atypia should be classified as GTs of uncertain malignant potential (GTUMPs). We report th... | ['Aged', 'Diagnosis, Differential', 'Forehead', 'Glomus Tumor', 'Humans', 'Male', 'Skin Neoplasms'] | 25,279,483 | [['M01.060.116.100'], ['E01.171'], ['A01.456.505.580'], ['C04.557.645.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.805', 'C17.800.882']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
End-of-life care for lung cancer patients in the United States and Ontario. | BACKGROUND: Both the United States and Canada offer government-financed health insurance for the elderly, but few studies have compared care at the end of life for cancer patients between the two systems.METHODS: We identified care for non-small cell lung cancer (NSCLC) patients who died of cancer at age 65 years and o... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Canada', 'Carcinoma, Non-Small-Cell Lung', 'Confounding Factors, Epidemiologic', 'Emergency Medical Services', 'Female', 'Health Services Accessibility', 'Hospice Care', 'Hospitalization', 'Humans', 'Lung Neoplasms', 'Male', 'Medicare', 'Ontario', 'Palliative ... | 21,593,012 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['Z01.107.567.176'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['N05.715.350.240', 'N06.850.490.718'], ['N02.421.297'], ['N04.590.374.350', 'N05.300.430'], ['E02.760.905.400', 'N02.421.585.905.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Exposure to the field of renal transplantation during undergraduate medical education in the UK. | BACKGROUND: There is a lack of surgeons in the field of renal transplantation, with a predicted shortage of over 20 consultants by the year 2005. Early positive exposure to the field, commencing at undergraduate level, has been identified as being vital to improving rates of recruitment. This study was performed to ass... | ['Adult', 'Career Choice', 'Clinical Competence', 'Curriculum', 'Education, Medical, Undergraduate', 'General Surgery', 'Humans', 'Kidney Transplantation', 'Personnel Selection', 'Schools, Medical', 'Surveys and Questionnaires', 'Teaching', 'United Kingdom', 'Workforce'] | 16,162,287 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.399.450'], ['H02.403.810.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['N04.452.677.500'], ['I02.783.495.552', 'N02.278.020.578'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Interrelationship between tetracycline resistance determinants, phylogenetic group affiliation and carriage of class 1 integrons in commensal Escherichia coli isolates from cattle farms. | BACKGROUND: Carriage of antibiotic-resistant foodborne pathogens by food production animals is one of many contributors to treatment failure in health care settings, and it necessitates an integrated approach to investigate the carriage of resistant pathogens harboring integrons in food-producing animals.METHODS: Esche... | ['Animals', 'Anti-Bacterial Agents', 'Cattle', 'Cattle Diseases', 'Escherichia coli', 'Escherichia coli Infections', 'Integrons', 'Microbial Sensitivity Tests', 'Phylogeny', 'Republic of Korea', 'Tetracycline', 'Tetracycline Resistance'] | 30,419,899 | [['B01.050'], ['D27.505.954.122.085'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['G02.111.570.080.708.330.200.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.697', 'G16.075.605', 'L01.100.697'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Versatile roles of Arabidopsis plastid ribosomal proteins in plant growth and development. | A lack of individual plastid ribosomal proteins (PRPs) can have diverse phenotypic effects in Arabidopsis thaliana, ranging from embryo lethality to compromised vitality, with the latter being associated with photosynthetic lesions and decreases in the expression of plastid proteins. In this study, reverse genetics was... | ['Arabidopsis', 'Arabidopsis Proteins', 'Chlorophyll', 'Chloroplast Proteins', 'Gene Expression Regulation, Plant', 'Mutagenesis, Insertional', 'Phenotype', 'Photosynthesis', 'Plants, Genetically Modified', 'Plastids', 'Reverse Genetics', 'Ribosomal Proteins', 'Ribosomes', 'Seedlings', 'Seeds'] | 22,900,828 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D12.776.765.199'], ['G05.308.375'], ['E05.393.420.601.550', 'G05.365.590.575', 'G05.558.550'], ['G05.695'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.49... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. | BACKGROUND: Giant-cell tumour of bone (GCTB) is a rare, locally aggressive osteoclastogenic stromal tumour of the bone. This phase 2 study aimed to assess the safety and activity of denosumab in patients with surgically salvageable or unsalvageable GCTB.METHODS: In this multicentre, open-label, phase 2 study done at 30... | ['Adult', 'Bone Density Conservation Agents', 'Bone Neoplasms', 'Denosumab', 'Female', 'Follow-Up Studies', 'Giant Cell Tumor of Bone', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prognosis', 'Survival Rate'] | 31,704,134 | [['M01.060.116'], ['D27.505.696.242'], ['C04.588.149', 'C05.116.231'], ['D12.776.124.486.485.114.224.060.782', 'D12.776.124.790.651.114.224.060.782', 'D12.776.377.715.548.114.224.200.782'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.557.450.565.380.380', 'C04.557.45... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Host origin of the human hematopoietic microenvironment following allogeneic bone marrow transplantation. | The origin of marrow stromal cells post allogeneic bone marrow transplantation (BMT) was studied. Two groups of patients receiving HLA-identical marrow grafts from sex mismatched siblings were included in the study: the first group (eight patients) received conventional marrow grafts and the second group (ten patients)... | ['Adolescent', 'Anemia, Aplastic', 'Bone Marrow Cells', 'Bone Marrow Transplantation', 'Cells, Cultured', 'Child', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Humans', 'Karyotyping', 'Leukemia'] | 3,315,046 | [['M01.060.057'], ['C15.378.071.085', 'C15.378.190.223.250'], ['A11.148', 'A15.378.316'], ['E02.095.147.725.040', 'E04.936.580.040'], ['A11.251'], ['M01.060.406'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.31... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blood pressure responses to dietary sodium manipulation during normotensive human pregnancy. | Short-term salt loading and salt restriction in a group of normal pregnant women produced no changes in lying, sitting or standing blood pressures or heart rates. Home blood pressures showed no trend to change over the periods of altered salt intake. Although plasma volume and plasma renin activity changed with altered... | ['Adolescent', 'Adult', 'Blood Pressure', 'Diet', 'Female', 'Humans', 'Plasma Volume', 'Pregnancy', 'Sodium'] | 4,028,520 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.188.130.610', 'G09.330.380.092.610'], ['G08.686.784.769'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Caffeine down-regulates beta adrenoreceptors in rat forebrain. | We studied the influence of caffeine treatment (50 mg/kg for 3 doses) on catecholamine utilization and adrenergic receptor binding in female rats. Caffeine enhanced the reduction in forebrain norepinephrine levels following alpha-methyl-p-tyrosine without altering the reduction in dopamine levels. Caffeine reduced the ... | ['Animals', 'Binding, Competitive', 'Brain', 'Caffeine', 'Clonidine', 'Dihydroalprenolol', 'Dopamine', 'Female', 'Methyltyrosines', 'Norepinephrine', 'Prazosin', 'Rats', 'Rats, Inbred Strains', 'Receptors, Adrenergic', 'Receptors, Adrenergic, beta', 'Synaptic Transmission', 'alpha-Methyltyrosine'] | 6,289,200 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A08.186.211'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D03.383.129.308.436.500'], ['D02.033.100.624.698.055.200', 'D02.033.755.624.698.055.200', 'D02.092.063.624.698.055.200'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.55... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enrichment of neurons and neural precursors from human embryonic stem cells. | Human embryonic stem (hES) cells proliferate and maintain their pluripotency for over a year in vitro (M. Amit, M. K. Carpenter, M. S. Inokuma, C. P. Chiu, C. P., Harris, M. A. Waknitz, J. Itskovitz-Eldor, and J. A. Thomson. 2000. Dev. Biol. 227: 271-278) and may therefore provide a cell source for cell therapies. hES ... | ['Calcium', 'Cell Differentiation', 'Cells, Cultured', 'Cellular Senescence', 'Electrophysiology', 'Embryo, Mammalian', 'Humans', 'Neurons', 'Stem Cells'] | 11,716,562 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.152'], ['A11.251'], ['G04.043'], ['H01.158.344.528', 'H01.158.782.236'], ['A16.254'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675', 'A11.671'], ['A11.872']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Malnourished elderly people and lipid status. | UNLABELLED: Protein-energy malnutrition is common in the elderly. The relationship between protein-energy malnutrition and lipid status remains uncertain and few studies are available. The aim of this study was to evaluate the lipid status of malnourished elderly subjects recently hospitalized in a geriatric medical ca... | ['Aged', 'Aged, 80 and over', 'Apolipoprotein A-I', 'Apolipoproteins B', 'Cholesterol', 'Cholesterol, HDL', 'Female', 'Hospitalization', 'Humans', 'Lipids', 'Male', 'Nutrition Assessment', 'Nutrition Disorders', 'Protein-Energy Malnutrition', 'Serum Albumin', 'Vitamin A', 'Vitamin E'] | 12,459,887 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
P2Y2 receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells. | INTRODUCTION: Extracellular nucleotides are released and detectable in a high concentration within the tumor microenvironment. G protein-coupled P2Y2 nucleotide receptor (P2Y2R) is activated equipotently by adenosine triphosphate (ATP) and uridine 5'-triphosphate (UTP), which mediate proinflammatory responses such as c... | ['Adenosine Triphosphate', 'Animals', 'Antigens, CD', 'Breast Neoplasms', 'Cadherins', 'Cell Communication', 'Cell Movement', 'Cell Proliferation', 'Endothelial Cells', 'Female', 'Humans', 'Lung Neoplasms', 'MCF-7 Cells', 'Matrix Metalloproteinase 9', 'Mice, Nude', 'Neoplasm Transplantation', 'Phosphorylation', 'Protei... | 25,156,554 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['G04.085'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.34... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experimentation with psychoactive substances by public school students. | OBJECTIVE: To analyze the prevalence of exposure to psychoactive substances in public students of basic education and its association with sociodemographic characteristics.METHODS: This is a cross-sectional survey conducted from March to September 2015, involving 1,009 students of the basic and high school education in... | ['Adolescent', 'Adolescent Behavior', 'Adult', 'Age Distribution', 'Alcohol Drinking', 'Brazil', 'Child', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Prevalence', 'Psychotropic Drugs', 'Religion', 'Risk Factors', 'Smoking', 'Students', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Young Adul... | 28,876,413 | [['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['F01.145.317.269'], ['Z01.107.757.176'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Humanities [K]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The induction of unscheduled DNA synthesis by antihistamines in primary hepatocyte cultures. | The autoradiographic identification of chemically-induced, unscheduled DNA synthesis in primary cultures of adult rat hepatocytes is currently being validated as a predictive test for mutagens/carcinogens. Of 8 antihistaminic drugs tested, 2, pyrilamine maleate and tripelennamine HCl, were positive for unscheduled DNA ... | ['Animals', 'Autoradiography', 'Carcinogens', 'DNA', 'Dose-Response Relationship, Drug', 'Histamine H1 Antagonists', 'Liver', 'Rats'] | 6,112,061 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D27.888.569.100'], ['D13.444.308'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.625.375.425.400', 'D27.505.696.577.375.425.400'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins. | Expansion of the genetic code with unnatural amino acids (Uaas) has significantly increased the chemical space available to proteins for exploitation. Due to the inherent limitation of translational machinery and the required compatibility with biological settings, function groups introduced via Uaas to date are restri... | ['Alanine', 'Aminobutyrates', 'Models, Molecular', 'Protein Engineering', 'Protein Structure, Secondary'] | 31,038,942 | [['D12.125.042'], ['D02.241.081.114.500', 'D12.125.190'], ['E05.599.595'], ['E05.393.420.601'], ['G02.111.570.820.709.600']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Technical Considerations for Implementation of Tele-Ethics Consultation in the Intensive Care Unit. | BACKGROUND: Robust ethics consultation services cannot be sustained by all hospitals; consultative service from a high-volume center via teleconferencing is an attractive alternative. This pilot study was conceived to explore the feasibility and understand the practical implications of offering such a service.METHODS: ... | ['Ethicists', 'Ethics Consultation', 'Ethics, Clinical', 'Humans', 'Intensive Care Units', 'Pilot Projects'] | 30,605,438 | [['K01.752.566.479.119', 'M01.526.276', 'N05.350.262'], ['K01.752.566.479.117.200', 'N04.452.758.849.174', 'N05.350.250.200'], ['K01.752.566.479.045.500', 'K01.752.566.479.171.132', 'N05.350.200.500', 'N05.350.340.162'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E05.318.372.750', 'E05.337.... | ['Humanities [K]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Salvage radical prostatectomy after failure of curative radiotherapy for adenocarcinoma of prostate. | Radical prostatectomy with curative intent was performed in 13 patients with prostate cancer after local failure of radiotherapy. Of these patients, 2 underwent cystoprostatectomy for bladder neck involvement by the prostatic tumor. Local recurrence had been diagnosed twenty-one to one hundred sixty-eight months (mean ... | ['Adenocarcinoma', 'Aged', 'Combined Modality Therapy', 'Follow-Up Studies', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Prostatectomy', 'Prostatic Neoplasms', 'Salvage Therapy'] | 1,523,739 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['E02.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E04.950.774.860.625'], ['C04.588.945.440.770', 'C12.2... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mutations in the Neuronal Vesicular SNARE VAMP2 Affect Synaptic Membrane Fusion and Impair Human Neurodevelopment. | VAMP2 encodes the vesicular SNARE protein VAMP2 (also called synaptobrevin-2). Together with its partners syntaxin-1A and synaptosomal-associated protein 25 (SNAP25), VAMP2 mediates fusion of synaptic vesicles to release neurotransmitters. VAMP2 is essential for vesicular exocytosis and activity-dependent neurotransmit... | ['Adolescent', 'Autistic Disorder', 'Brain', 'Child', 'Child, Preschool', 'Epilepsy', 'Exocytosis', 'Female', 'Heterozygote', 'Humans', 'Intellectual Disability', 'Lipids', 'Magnetic Resonance Imaging', 'Male', 'Membrane Fusion', 'Movement Disorders', 'Muscle Hypotonia', 'Mutation', 'Neurodevelopmental Disorders', 'Neu... | 30,929,742 | [['M01.060.057'], ['F03.625.164.113.500'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.490'], ['G04.468'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['D10'], ['E01.370.350.825.500'], ['G04.575'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Smoking Cessation without Educational Instruction could Promote the Development of Metabolic Syndrome. | AIM: Smoking cessation is particularly important for maintaining health; however, the subsequent risk of an increased body weight is of major concern. The present study investigated the influence of smoking cessation on the incidence of metabolic syndrome and its components in the Japanese general population.METHODS: T... | ['Aged', 'Body Mass Index', 'Body Weight', 'Cohort Studies', 'Female', 'Humans', 'Incidence', 'Japan', 'Kaplan-Meier Estimate', 'Life Style', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Patient Education as Topic', 'Proportional Hazards Models', 'Risk Factors', 'Smoking', 'Smoking Cessation', 'Tobacco Use Disorder', ... | 28,592,705 | [['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Long-term results of esotropia surgery in children with developmental delay. | PURPOSE: To assess the long-term results of esotropia surgery in children with developmental delay who were operated on with reduced surgical dosages.METHODS: This was a retrospective analysis of children with developmental delay who had undergone surgery for esotropia during a 16-year period. The pre- and postoperativ... | ['Adolescent', 'Child', 'Child, Preschool', 'Developmental Disabilities', 'Esotropia', 'Exotropia', 'Female', 'Humans', 'Infant', 'Male', 'Postoperative Complications', 'Refraction, Ocular', 'Refractive Errors', 'Retrospective Studies', 'Treatment Outcome'] | 22,370,662 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['F03.625.421'], ['C10.292.562.887.300', 'C11.590.810.400'], ['C10.292.562.887.650', 'C11.590.810.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C23.550.767'], ['E01.370.380.850.700', 'G01.590.775', 'G14.760'], ['C11.744'], ['E05.318.37... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The medical investigation of airship accidents. | A review of the autopsy reports for 18 of 21 victims in 3 of the 4 nonrigid Navy airship accidents during the period 1955 to 1966 revealed that the patterns of injury, complicated by postcrash entrapment, immersion, or fire, are similar to the injuries observed in the low-speed, low-altitude crashes of rigid airships a... | ['Accidents, Aviation', 'Aircraft', 'Cause of Death', 'Equipment Design', 'Humans', 'Male', 'Safety', 'Wounds and Injuries'] | 3,171,506 | [['N06.850.135.185'], ['J01.937.285.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.135.060.075'], ['C26']] | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Radionuclide assessment of peritoneo-venous shunt patency. | LeVeen shunt patency can be easily assessed by sequential scintigraphy with a gamma camera after an intraperitoneal injection of Tc-99m-macroaggregated albumin (Tc-99m-MAA). If the shunt is patent, the particles of MAA reach the pulmonary capillary bed and the lungs are visualized. The activity in the lungs is easily d... | ['Ascites', 'Female', 'Humans', 'Liver Cirrhosis', 'Liver Cirrhosis, Alcoholic', 'Lung', 'Male', 'Methods', 'Middle Aged', 'Peritoneal Cavity', 'Postoperative Complications', 'Radionuclide Imaging', 'Serum Albumin', 'Technetium'] | 509,842 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Requirements on evidence for system-level decision making regarding the adoption of medical services into the Statutory Health Insurance (SHI) catalogue]. | In Germany, recommendations regarding health care (system) decisions dealing with medical services which are to be included in (or excluded from) the SHI benefit catalogue clearly relate to the principles of evidence-based health care which can be defined as "the conscientious, explicit and judicious use of the current... | ['Decision Making', 'Delivery of Health Care', 'Evidence-Based Medicine', 'Germany', 'Humans', 'Insurance Benefits', 'Insurance, Health'] | 21,129,701 | [['F02.463.785.373'], ['N04.590.374', 'N05.300'], ['H02.249.750', 'H02.403.200.400'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.130'], ['N03.219.521.576.343']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Image generation of serotonin synthesis rates using alpha-methyltryptophan and PET. | PURPOSE: We sought to create functional images of the serotonin (5-HT) synthesis rate obtained with alpha-[11C]methyl-L-tryptophan (alpha-MTrp) and PET and standardize them into the stereotaxic coordinate system.METHOD: Dynamic PET scans were performed in 11 healthy subjects after an injection of alpha-MTrp. Results ob... | ['Adult', 'Analysis of Variance', 'Brain', 'Carbon Radioisotopes', 'Humans', 'Linear Models', 'Magnetic Resonance Imaging', 'Male', 'Radiopharmaceuticals', 'Reference Values', 'Serotonin', 'Stereotaxic Techniques', 'Tomography, Emission-Computed', 'Tryptophan'] | 9,754,116 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A08.186.211'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An outbreak of waterborne cryptosporidiosis in Swindon and Oxfordshire. | An outbreak of cryptosporidiosis resulted in 516 cases in Wiltshire and Oxfordshire. The outbreak caused widespread interest and led to an official inquiry. The majority of cases were in children; 8% of cases were admitted to hospital and the median duration of illness was 3 weeks. The geographical distribution of case... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Animals', 'Child', 'Child, Preschool', 'Cryptosporidiosis', 'Cryptosporidium', 'Disease Outbreaks', 'England', 'Feces', 'Female', 'Humans', 'Incidence', 'Infant', 'Male', 'Middle Aged', 'Risk Factors', 'Seasons', 'Sex Factors', 'Surveys and Questionnaires', 'Water Supply'... | 1,752,298 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['C01.610.432.269', 'C01.610.701.688.235', 'C01.610.752.250.269', 'C01.610.752.625.235', 'C06.405.469.452.269', 'C22.674.710.235'], ['B01.043.075.189.250.150.160'], ['N06.85... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Age-induced reprogramming of mast cell degranulation. | Mast cell degranulation can initiate an acute inflammatory response and contribute to the progression of chronic diseases. Alteration in the cellular programs that determine the requirement for mast cell degranulation would therefore have the potential to dramatically impact disease severity. Mast cells are exposed to ... | ['Age Factors', 'Alprostadil', 'Animals', 'Cell Degranulation', 'Dermatitis', 'Edema', 'Immunoglobulin E', 'Mast Cells', 'Mice', 'Mice, Inbred C57BL', 'Passive Cutaneous Anaphylaxis', 'Receptors, Prostaglandin E', 'Receptors, Prostaglandin E, EP1 Subtype', 'Receptors, Prostaglandin E, EP3 Subtype'] | 16,237,060 | [['N05.715.350.075', 'N06.850.490.250'], ['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['G04.468.160'], ['C17.800.174'], ['C23.888.277'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['A11.329.427', 'A15.... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Calcium efflux associated with encystment of Phytophthora palmivora zoospores. | Zoospores of the fungus Phytophthora palmivora, pre-labeled with 45Ca, excreted up to 30% of their total 45Ca when stimulated to encyst. Excretion was essentially completed within 90 sec of the application of the stimulus. Encystment of the population was completed within 5 min. Four different stimuli were used: pectin... | ['Adenine Nucleotides', 'Biological Transport', 'Calcium', 'Egtazic Acid', 'Fungi', 'Nucleotides, Cyclic', 'Phytophthora', 'Potassium', 'Spores, Fungal'] | 6,440,711 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['B01.300'], ['D13.695.462'], ['B01.750.580.715'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['A... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disciplinary procedures. Cautionary tales. | HVA local accredited representatives are reporting an increase in disciplinary cases against field staff. Disciplinary cases can be very stressful for all concerned. They should not be used unless clearly appropriate, as Roger Kline explains. | ['Community Health Nursing', 'Employee Discipline', 'Humans', 'Labor Unions'] | 8,194,985 | [['H02.478.676.150', 'N02.421.143.150'], ['N04.452.677.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.571']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of communication mode on the development of phonemic awareness in prelingually deaf students. | Two groups of prelingually deaf children and a hearing control group participated in an experiment examining the effect of communication mode on the development of phonemic awareness. Sixteen of the deaf students (mean grade 6.9) were trained orally, using spoken language as their principal means for communication at h... | ['Adolescent', 'Child', 'Communication', 'Deafness', 'Female', 'Humans', 'Male', 'Phonetics', 'Severity of Illness Index', 'Speech Perception'] | 9,328,886 | [['M01.060.057'], ['M01.060.406'], ['F01.145.209', 'L01.143'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.518'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Copy number variation in patients with cervical artery dissection. | Cervical artery dissection (CeAD) occurs in healthy young individuals and often entails ischemic stroke. Skin biopsies from most CeAD-patients show minor connective tissue alterations. We search for rare genetic deletions and duplication that may predispose to CeAD. Forty-nine non-traumatic CeAD-patients with electron ... | ['Adult', 'Carotid Artery, Internal, Dissection', 'Case-Control Studies', 'Collagen', 'Connective Tissue', 'DNA Copy Number Variations', 'Extracellular Matrix', 'Female', 'Gene Deletion', 'Gene Duplication', 'Genetic Association Studies', 'Genetic Loci', 'Humans', 'Male', 'Transforming Growth Factors', 'Vertebral Arter... | 22,617,347 | [['M01.060.116'], ['C10.228.140.300.200.345.300', 'C10.228.140.300.350.500.300', 'C10.900.250.300.300', 'C14.907.055.050.150', 'C14.907.253.123.345.300', 'C14.907.253.535.500.300', 'C26.915.200.200.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D05.750.078.280', 'D12.776.860.300... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of intermittent and continuous use of a gonadotropin-releasing hormone antagonist (Nal-Glu) in in vitro fertilization cycles: a preliminary report. | The agonistic effect of the gonadotropin-releasing hormone agonist often necessitates an extended period of treatment, resulting in a longer treatment cycle and increased cost. We have evaluated the intermittent use of a gonadotropin-releasing hormone antagonist, Nal-Glu, and have designed a new, simplified protocol fo... | ['Adult', 'Chorionic Gonadotropin', 'Down-Regulation', 'Estradiol', 'Female', 'Fertilization in Vitro', 'Gonadotropin-Releasing Hormone', 'Humans', 'Leuprolide', 'Luteinizing Hormone', 'Menotropins', 'Ovulation'] | 1,750,479 | [['M01.060.116'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Targeting mitochondria with methylene blue protects mice against acetaminophen-induced liver injury. | UNLABELLED: Acetaminophen (APAP) overdose is a frequent cause of drug-induced liver injury and the most frequent cause of acute liver failure in the Western world. Previous studies with mouse models have revealed that impairment of mitochondrial respiration is an early event in the pathogenesis, but the exact mechanism... | ['Acetaminophen', 'Analgesics, Non-Narcotic', 'Animals', 'Benzoquinones', 'Cell Death', 'Cells, Cultured', 'Chemical and Drug Induced Liver Injury', 'Drug Evaluation, Preclinical', 'Electron Transport Complex II', 'Enzyme Inhibitors', 'Hepatocytes', 'Imines', 'Liver', 'Male', 'Methylene Blue', 'Mice, Inbred C57BL', 'Mi... | 25,142,022 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['B01.050'], ['D02.806.250'], ['G04.146'], ['A11.251'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['E05.290.750', 'E05.337.550'], ['D05.500.562.750.249', 'D08.811.600.250.500.750', 'D08.811.600.250.875.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Removal of copper ions from dilute solutions by Streptomyces noursei mycelium. Comparison with yeast biomass. | Sorption properties of Streptomyces noursei mycelium for copper ions were compared with the accumulation competence of dried and native yeast (Candida utilis) biomass. The copper sorption capacity of S. noursei after optimization was found to be higher than that of the two other adsorbents (dried yeast biomass 82 %, na... | ['Adsorption', 'Biomass', 'Candida', 'Copper', 'Hydrogen-Ion Concentration', 'Industrial Microbiology', 'Mycelium', 'Solutions', 'Streptomyces', 'Water Purification'] | 16,408,849 | [['G01.030', 'G02.020'], ['G16.500.275.157.100', 'N06.230.124.100'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G02.300'], ['H01.158.273.540.460', 'J01.897.120.460'], ['A19.687'], ['D26.776'], ['B03.300.390.400.810.768', 'B03.510.024.997.7... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Comparison of the genetic variability of Blastocystis subtypes between human carriers from two contrasting climatic regions of M?xico. | Blastocystis sp. is an anaerobic intestinal microorganism commonly identified in the feces of several animals, including humans. Blastocystis exhibits high genetic polymorphism and at least 17 subtypes (ST) have been identified; ST1-ST3 are frequently found in the Americas. Furthermore, in vitro assays have shown that ... | ['Adolescent', 'Adult', 'Aged', 'Blastocystis', 'Blastocystis Infections', 'Carrier State', 'Child', 'Child, Preschool', 'Climate', 'Female', 'Genetic Variation', 'Genotype', 'Haplotypes', 'Humans', 'Infant', 'Male', 'Mexico', 'Middle Aged', 'Phylogeny', 'Polymorphism, Genetic', 'RNA, Ribosomal', 'Sequence Analysis, DN... | 27,476,606 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.046.500.100.200.200'], ['C01.610.432.250', 'C01.610.752.049.250', 'C06.405.469.452.250'], ['N06.850.520.169'], ['M01.060.406'], ['M01.060.406.448'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G05.365'], ['G05.380'], ['G05.380.360'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Echocardiographic criteria of the diagnosis of mitral-semilunar valve continuity. | A prospective echocardiographic study of 39 healthy adults with no history of heart disease was conducted to investigate the relationship between the anterior mitral valve leaflet (AMVL) and the posterior aortic root (PAR). The difference between the echocardiographic depth of the AMVL and the depth of the PAR with res... | ['Adult', 'Aorta', 'Aortic Valve', 'Echocardiography', 'Female', 'Heart Valve Diseases', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Posture', 'Prospective Studies', 'Pulmonary Valve'] | 851,056 | [['M01.060.116'], ['A07.015.114.056'], ['A07.541.510.110'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.507'], ['G11.427.695'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Topography of the quail retina]. | Retinas of quails (Coturnix coturnix japonica) were studied by light microscopy. By this, an area centralis with high cell density could be demonstrated. Moreover, in the posterior-superior retina there exists a region of moderate cell density containing a central red field with a high concentration of cones with red o... | ['Animals', 'Cell Count', 'Coturnix', 'Photoreceptor Cells', 'Quail', 'Retina', 'Visual Fields'] | 6,673,390 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['B01.050.150.900.248.350.650.350'], ['A08.675.650.850.625', 'A08.675.650.915.937', 'A08.800.950.937', 'A09.371.729.831.625', 'A11.671.650.850.625', 'A11.671.650.915.937'], ['B01.050.150.900.248.350.650'], ['A09.371.729'], ['F02.463.593... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Inherent morphofunctional effects of experimental procedures in studying the mechanism of transmitter release]. | Muscle detubulation with the aid of glycerin is widely used in studying synaptic transmission in the neuromuscular junction. In view of this fact, it was decided to examine its effects on structural and functional parameters of the neuromuscular junction of rat diaphragmal muscle. It was shown that the structure of the... | ['Animals', 'Glycerol', 'In Vitro Techniques', 'Neuromuscular Junction', 'Neurotransmitter Agents', 'Rats'] | 2,859,056 | [['B01.050'], ['D02.033.800.875.500', 'D09.853.875.500'], ['E05.481'], ['A08.800.550.550.550', 'A08.850.550.550', 'A11.284.149.165.420.780.550.550'], ['D27.505.519.625', 'D27.505.696.577'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolonged transcutaneous cardiopulmonary support for postcardiotomy cardiogenic shock. | Percutaneous cardiopulmonary support can be set up quickly at the bedside and provides reliable temporary mechanical circulatory support for cardiogenic shock patients. This report includes the case of a woman, age 56 years, with postoperative cardiogenic shock due to right heart failure, secondary to severe pulmonary ... | ['Cardiopulmonary Bypass', 'Echocardiography', 'Fatal Outcome', 'Female', 'Heart Valve Prosthesis Implantation', 'Heart-Lung Machine', 'Humans', 'Hypertension, Pulmonary', 'Middle Aged', 'Point-of-Care Systems', 'Postoperative Complications', 'Recovery of Function', 'Shock, Cardiogenic', 'Ventricular Dysfunction, Right... | 17,515,711 | [['E04.292.413'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['E07.858.082.458'], ['B01.050.150.900.649.313.988.400.112.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A fatal case of anaphylactic shock during paragliding. | The growth in popularity of flying ultralight aircraft and paragliding has been associated with an increased involvement of Emergency Medical Services because of various types of trauma suffered from both inexperienced and skilled individuals. This case presentation reports on a paraglider pilot, who was seen spinning ... | ['Anaphylaxis', 'Animals', 'Bees', 'Edema', 'Forensic Medicine', 'Humans', 'Insect Bites and Stings', 'Leisure Activities', 'Male', 'Mouth'] | 22,563,914 | [['C20.543.480.099'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['C23.888.277'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.723.127.071', 'C26.176.143'], ['I03.450'], ['A01.456.505.631', 'A03.556.500', 'A14.549']] | ['Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Recommendations for fertility preservation in patients with lymphomas. | PURPOSE: This guideline aims to serve as a reference for fertility specialists and other specialists working with young patients at risk of premature ovarian insufficiency (POI) or testicular dysfunction (TD) due to treatment of Hodgkin or Non-Hodgkin lymphoma.METHODS: PubMed search of articles addressing risk of POI a... | ['Antineoplastic Combined Chemotherapy Protocols', 'Bleomycin', 'Cryopreservation', 'Dacarbazine', 'Doxorubicin', 'Female', 'Fertility Preservation', 'Gonadotropin-Releasing Hormone', 'Hodgkin Disease', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Oocytes', 'Ovary', 'Primary Ovarian Insufficiency', 'Semen Preservation',... | 22,562,284 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D09.400.420.110', 'D12.644.233.110'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['D02.925.200', 'D03.383.129.308.240'], ['D02.455.426.559.847.562.050.20... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nitric oxide-induced conformational changes in soluble guanylate cyclase. | Soluble guanylate cyclase (sGC) is the primary mediator of nitric oxide (NO) signaling. NO binds the sGC heme cofactor stimulating synthesis of the second messenger cyclic-GMP (cGMP). As the central hub of NO/cGMP signaling pathways, sGC is important in diverse physiological processes such as vasodilation and neurotran... | ['Amino Acid Sequence', 'Catalytic Domain', 'Cyclic GMP', 'Escherichia coli', 'Gene Expression', 'Guanylate Cyclase', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Nitric Oxide', 'Protein Binding', 'Protein Folding', 'Protein Multimerization', 'Protein Structure, Secondary', 'Protein Subunits', 'Receptors,... | 24,560,804 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
IFN-ã regulates CD8+ memory T cell differentiation and survival in response to weak, but not strong, TCR signals. | In response to primary Ag contact, naive mouse CD8(+) T cells undergo clonal expansion and differentiate into effector T cells. After pathogen clearance, most effector T cells die, and only a small number of memory T cell precursors (TMPs) survive to form a pool of long-lived memory T cells (TMs). Although high- and lo... | ['Animals', 'CD8-Positive T-Lymphocytes', 'Cell Differentiation', 'Cell Survival', 'Immunologic Memory', 'Interferon-gamma', 'L-Selectin', 'Mice', 'Mice, Knockout', 'Proto-Oncogene Proteins c-bcl-2', 'Receptors, Antigen, T-Cell', 'Receptors, Interferon', 'Signal Transduction', 'T-Box Domain Proteins', 'TOR Serine-Threo... | 25,480,562 | [['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04.152'], ['G04.346'], ['G12.450.050.500'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Compensation of vestibular symptoms in hemilabyrinthectomized guinea pigs. Role of the sensorimotor activation. | The effect of sensorimotor activation on compensatory rate of vestibular asymmetries after unilateral labyrinthectomy was analyzed in guinea pigs. An intensified sensorimotor activation was obtained by putting in water the animals immediately after the appearance of hemilabyrinthectomy (HL) symptoms. The water-maintain... | ['Animals', 'Ear, Inner', 'Eye Movements', 'Guinea Pigs', 'Mechanoreceptors', 'Motor Activity', 'Nystagmus, Physiologic', 'Postural Balance', 'Posture', 'Proprioception', 'Swimming', 'Vestibular Nerve'] | 6,871,018 | [['B01.050'], ['A09.246.300'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.992.550'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['F01.145.632', 'G11.427.410.698'], ['G14.350.378'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G11.427.695'], [... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Ethanol interactions with a choline-deficient, ethionine-supplemented feeding regime potentiate pre-neoplastic cellular alterations in rat liver. | To examine the effect of ethanol on hepatocarcinogenesis induced by a choline-deficient, ethionine-supplemented (CDE) diet, rats were fed either an ethanol-supplemented diet or ethanol-free, isocaloric diet for 2 months, followed by a CDE diet or control diet for up to 8 months. Changes to cellular composition and patt... | ['Animals', 'Choline Deficiency', 'Dietary Supplements', 'Ethanol', 'Ethionine', 'Gene Expression Regulation, Enzymologic', 'Glutathione Transferase', 'Isoenzymes', 'Liver', 'Male', 'Precancerous Conditions', 'Pyruvate Kinase', 'Rats', 'Rats, Wistar', 'Time Factors', 'Transcription, Genetic', 'alpha-Fetoproteins'] | 12,376,478 | [['B01.050'], ['C18.654.521.500.133.699.160'], ['G07.203.300.456', 'J02.500.456'], ['D02.033.375'], ['D02.886.030.388', 'D12.125.166.388'], ['G05.308.320'], ['D08.811.913.225.500'], ['D08.811.348', 'D12.776.800.300'], ['A03.620'], ['C04.834'], ['D08.811.913.696.620.695'], ['B01.050.150.900.649.313.992.635.505.700'], ['... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Role of the Wound, Ostomy and Continence Nurse in Continence Care: 2018 Update. | The Wound, Ostomy and Continence Nurses Society believes the tri-specialty certified nurse (Certified Wound Ostomy Continence Nurse [CWOCN]) or advanced practice tri-specialty certified nurse (Certified Wound Ostomy Continence Nurse-Advanced Practice [CWOCN-AP]) possesses unique knowledge, expertise for assessment, and... | ['Fecal Incontinence', 'Humans', "Nurse's Role", 'Ostomy', 'Pressure Ulcer', 'Skin Care', 'Specialties, Nursing', 'Urinary Incontinence', 'Wound Healing'] | 31,083,065 | [['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['E04.579'], ['C17.800.893.665'], ['E02.547.800'], ['H02.478.676'], ['C12.777.934.852', 'C13.351.968.934.814', 'C23.888.942.343.800'], ['G16.762.891']] | ['Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Central performance drop in texture segmentation: the role of spatial and temporal factors. | Previous studies reported that performance in texture segmentation was lower near the fovea than in the periphery. However, the exact cause of this phenomenon had been unknown. Experiment 1 replicated the central performance drop (CPD). Experiments 2 and 3 demonstrated that the previously reported CPD was due to a temp... | ['Analysis of Variance', 'Humans', 'Pattern Recognition, Visual', 'Perceptual Masking', 'Visual Fields', 'Visual Pathways'] | 11,115,679 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.071.594', 'F02.463.593.932.733', 'G07.888.125.594'], ['F02.463.593.932.934', 'G14.950'], ['A08.612.220.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Feasibility and acceptability of a beverage intervention for Hispanic adults: a protocol for a pilot randomized controlled trial. | BACKGROUND: In the U.S., Hispanics have among the highest rates of overweight and obesity when compared to other racial/ethnic groups placing them at a greater risk for obesity-related disease. Identifying intervention strategies to reduce caloric intake and/or improve cardiometabolic health in Hispanics is critical to... | ['Adolescent', 'Adult', 'Beverages', 'Choice Behavior', 'Feasibility Studies', 'Hispanic Americans', 'Humans', 'Middle Aged', 'Obesity', 'Patient Acceptance of Health Care', 'Pilot Projects', 'Randomized Controlled Trials as Topic', 'Young Adult'] | 29,426,328 | [['M01.060.057'], ['M01.060.116'], ['G07.203.100', 'J02.200'], ['F02.463.785.373.346'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Loss of body mass in ex-prisoners of war. | Body mass was examined in the defenders of Vukovar (n = 71) from eastern Slavonia, Republic of Croatia, immediately on release from enemy concentration camps. The sample consisted of a group of 33 male smokers who had been imprisoned for (mean +/- SD) 127.4 +/- 18.4 days (age 31.6 +/- 7.2 years) and 38 male smokers, im... | ['Adipose Tissue', 'Adult', 'Anthropometry', 'Body Mass Index', 'Concentration Camps', 'Croatia', 'Erythrocyte Indices', 'Hematocrit', 'Humans', 'Male', 'Prisoners', 'Sampling Studies', 'Smoking', 'Time Factors', 'Warfare'] | 8,287,851 | [['A10.165.114'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['I01.880.604.787.358', 'J03.200'], ['Z01.542.248.295'], ['E01.370.225.625.230', 'E05.200.625.230', 'G09.188.260'], ['E01.370.225.625.40... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and... | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[BIOCHEMICAL MARKERS OF MYOCARDIAL DAMAGE IN CHILDREN AFTER SURGICAL CORRECTION OF CONGENITAL HEART DISEASE]. | The results of observations of 184 children from the CHD after surgical correction on which explored the biochemical markers of myocardial injury in serum--myocardial fraction of creatine kinase and galectin-3. The relationship between increased serum concentrations of these markers, clinical and paraclinical character... | ['Adolescent', 'Biomarkers', 'Child', 'Child, Preschool', 'Creatine Kinase, MB Form', 'Female', 'Galectin 3', 'Gene Expression', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Male', 'Myocardium'] | 26,118,042 | [['M01.060.057'], ['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['D08.811.913.696.640.150.625'], ['D12.776.503.307.300'], ['G05.297'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Importance of Highly Conserved Peptide Sites of Human Cytomegalovirus gO for Formation of the gH/gL/gO Complex. | The glycoprotein O (gO) is betaherpesvirus specific. Together with the viral glycoproteins H and L, gO forms a covalent trimeric complex that is part of the viral envelope. This trimer is crucial for cell-free infectivity of human cytomegalovirus (HCMV) but dispensable for cell-associated spread. We hypothesized that t... | ['Amino Acid Sequence', 'Amino Acids', 'Animals', 'Cell Line', 'Cloning, Molecular', 'Conserved Sequence', 'Cytomegalovirus', 'Endothelial Cells', 'Escherichia coli', 'Fibroblasts', 'Gene Expression', 'Humans', 'Membrane Glycoproteins', 'Mutation', 'Primary Cell Culture', 'Protein Multimerization', 'Recombinant Protein... | 27,795,411 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['B01.050'], ['A11.251.210'], ['E05.393.220'], ['G02.111.570.580'], ['B04.280.382.150.150'], ['A11.436.275'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.329.228'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The beginning of stroke prevention by surgery. | Normal variations in the crossflow capacity of the Circle of Willis, and the effects of disease upon this and on the thromboembolic potential of the cervical carotid, together account for the clinical unpredictability of strokes. These two factors form a recurring theme in the history of stroke studies, from 1664 with ... | ['Arteriosclerosis', 'Carotid Artery, Internal', 'Carotid Stenosis', 'Cerebral Angiography', 'Cerebrovascular Circulation', 'Cerebrovascular Disorders', 'Circle of Willis', 'Endarterectomy, Carotid', 'History, 16th Century', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'History, 20th Centu... | 8,049,941 | [['C14.907.137.126'], ['A07.015.114.186.200.230'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['G09.330.100.159'], ['C10.228.140.300', 'C14.... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mass preparation of oligosaccharides by the hydrolysis of chondroitin sulfate polysaccharides with a subcritical water microreaction system. | The biological functions of chondroitin sulfate (CS) are executed by the interaction of specific oligosaccharide sequences in the polysaccharide chain with effective proteins. Thus, CS oligosaccharides are expected to have pharmacological applications. Furthermore, the demand for CS in health food supplements and medic... | ['Acetylgalactosamine', 'Animals', 'Cartilage', 'Chondroitin Sulfates', 'Chromatography, Gel', 'Chromatography, High Pressure Liquid', 'Hydrolysis', 'Molecular Weight', 'Oligosaccharides', 'Skates, Fish', 'Temperature', 'Water'] | 23,454,651 | [['D09.067.342.356.050'], ['B01.050'], ['A02.165', 'A10.165.382'], ['D09.698.373.200.300'], ['E05.196.181.400.250'], ['E05.196.181.400.300'], ['G02.380'], ['G02.494'], ['D09.698.629'], ['B01.050.150.900.493.370.870', 'B01.050.150.900.493.378.682'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex. | The promoter regions of active genes in the eukaryotic genome typically contain nucleosomes post-translationally modified with a trimethyl mark on histone H3 lysine 4 (H3K4), while transcriptional enhancers are marked with monomethylated H3K4. The flavin-dependent monoamine oxidase LSD1 (lysine-specific demethylase 1, ... | ['Arginine', 'Co-Repressor Proteins', 'DNA', 'Histone Demethylases', 'Humans', 'Kinetics', 'Models, Molecular', 'Nerve Tissue Proteins', 'Nucleosomes', 'Protein Binding'] | 25,916,846 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D12.776.930.780.625'], ['D13.444.308'], ['D08.811.682.662.582.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['D12.776.631'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.36... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estrogen receptor â causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2. | The role of estrogen receptor beta (ERâ) in breast cancer is unclear. ERâ is considered to have a protective role in breast cancer development based on findings demonstrating that ERâ expression inhibits ERá-mediated proliferation of breast cancer cells. We previously demonstrated that ERâ causes a ligand independent G... | ['Breast Neoplasms', 'CDC2 Protein Kinase', 'Cell Cycle Proteins', 'Cell Division', 'Cell Line, Tumor', 'Cyclin B1', 'Estrogen Receptor beta', 'Female', 'G2 Phase Cell Cycle Checkpoints', 'Gene Expression Regulation', 'Genes, jun', 'Humans', 'Immediate-Early Proteins', 'Nuclear Proteins', 'Nuclear Receptor Coactivator ... | 21,120,602 | [['C04.588.180', 'C17.800.090.500'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.776.744.360'], ['D12.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Esophageal cancer as second primary tumor after breast cancer radiotherapy. | BACKGROUND: An increased risk of esophageal cancer has been reported in survivors of breast cancer treated with radiotherapy. This study further characterizes this association.METHODS: Through hospital databases, 118 patients (109 men, 9 women) treated for esophageal cancer between 1985 and 1993 were identified, of who... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Breast Neoplasms, Male', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Neoplasms, Second Primary'] | 11,754,854 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.588.180.260', 'C17.800.090.500.260'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The hematotoxic effects of 6-hydroxy-trans,trans-2,4-hexadienal, a reactive metabolite of trans,trans-muconaldehyde, in CD-1 mice. | 6-Hydroxy-trans,trans-2,4-hexadienal (CHO-M-OH) is a metabolite of trans,trans-muconaldehyde (muconaldehyde or MUC), a microsomal hematotoxic ring-opened metabolite of benzene. In the present study, the toxicity of CHO-M-OH was examined. In order to assess potential toxic effects of CHO-M-OH on the maturation of erythr... | ['Aldehydes', 'Alkadienes', 'Animals', 'Bone Marrow', 'Hematologic Diseases', 'Iron', 'Iron Radioisotopes', 'Male', 'Mice'] | 7,785,050 | [['D02.047'], ['D02.455.326.271.665.146'], ['B01.050'], ['A15.382.216'], ['C15.378'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.268.556.412.500.498', 'D01.268.956.287.500.498', 'D01.496.473.498', 'D01.496.749.514', 'D01.552.544.412.500.498'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Atomization inhalation of terbutaline and budesonide efficiently improved immunity and lung function of AECOPD patients. | Chronic obstructive pulmonary disease (COPD) is a syndrome of chronic progressive airflow limitation as a result of chronic inflammation of the airways and lung parenchyma. COPD patients always have airway hyperreactivity (AHR), so how to reduce AHR becomes the key purpose of clinical treatment. It is hypothesized that... | ['Administration, Inhalation', 'Aged', 'Bronchial Hyperreactivity', 'Bronchodilator Agents', 'Budesonide', 'C-Reactive Protein', 'Eosinophils', 'Female', 'Humans', 'Interleukin-2', 'Male', 'Middle Aged', 'Pulmonary Disease, Chronic Obstructive', 'T-Lymphocyte Subsets', 'Terbutaline'] | 18,761,816 | [['E02.319.267.050'], ['M01.060.116.100'], ['C08.127.210'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['D04.210.500.745.745.654.105'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Analyzing the fine-scale dynamics of two dominant species in a Polytrichum—Myrtillus pine forest. I. A homogeneous Markov chain and cyclicity indices]. | Using long-term direct observations in a Polytrichum-Myrtillus pine forest, we have constructed and verified a homogeneous Markov chain model for two dominant species (Vaccinium myrtillus and V. vitis-idaed) at the late stages of succession. The sampling design features a large sample size (2000 quadrats) on permanent ... | ['Forests', 'Markov Chains', 'Models, Biological', 'Pinus', 'Vaccinium myrtillus', 'Vaccinium vitis-idaea'] | 30,024,669 | [['G16.500.275.157.437', 'N06.230.124.343'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.850.520.830.996.500'], ['E05.599.395'], ['B01.650.940.800.575.912.625.875.777'], ['B01.650.940.800.575.912.250.341.937.774.875'... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Abnormal binocular vision: monocular diplopia of physical origin: two case reports. Its relationship to the physiology and arrangement of the visual directions of the retinal areas; binocular triplopia. | BACKGROUND AND PURPOSE: Monocular diplopia is an infrequent but disabling complication following laser peripheral iridotomy, or following cataract surgery. Our purpose is to clarify the intraocular mechanism of monocular diplopia (and binocular triplopia) of physical origin and its relation to the physiology and arrang... | ['Aged', 'Aged, 80 and over', 'Capsule Opacification', 'Diplopia', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Iridectomy', 'Iris', 'Laser Therapy', 'Lasers, Solid-State', 'Lens Implantation, Intraocular', 'Male', 'Phacoemulsification', 'Retina', 'Vision, Binocular'] | 21,138,413 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.510.245.500'], ['C10.597.751.941.339', 'C11.966.339', 'C23.888.592.763.941.339'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E04.540.480'], ['A09.371.060.450', 'A09.371.894.513'], ['E02.594', 'E04.014.520'], ['E07.632.490.490... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Co-administration of a nitric oxide synthase inhibitor and melatonin exerts an additive antidepressant-like effect in the mouse forced swim test. | BACKGROUND: The aim was to assess the combination therapy of nitric oxide synthase inhibitors and melatonin, since they had been separately shown to be as efficacious as conventional antidepressant drugs in pre-clinical antidepressant screening procedures.MATERIAL/METHODS: The Porsolt swim test was conducted to resembl... | ['Animals', 'Antidepressive Agents', 'Depressive Disorder, Major', 'Drug Evaluation, Preclinical', 'Drug Synergism', 'Drug Therapy, Combination', 'Enzyme Inhibitors', 'Male', 'Melatonin', 'Mice', 'Mice, Inbred BALB C', 'Motor Activity', 'Nitric Oxide Synthase', 'Nitroarginine', 'Swimming'] | 16,940,926 | [['B01.050'], ['D27.505.954.427.700.122'], ['F03.600.300.375'], ['E05.290.750', 'E05.337.550'], ['G07.690.773.968.477'], ['E02.319.310'], ['D27.505.519.389'], ['D03.633.100.473.914.481', 'D06.472.506'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Neurofibromatosis 2: clinical and DNA linkage studies of a large kindred. | At least eight provisional categories of neurofibromatosis have been proposed. Among these, neurofibromatosis 1 (von Recklinghausen's disease or peripheral neurofibromatosis) and neurofibromatosis 2 (central or bilateral acoustic neurofibromatosis) have been established as distinct disorders. We studied 15 affected mal... | ['Adolescent', 'Adult', 'Age Factors', 'Brain Neoplasms', 'Chromosomes, Human, Pair 22', 'Ependymoma', 'Female', 'Genetic Linkage', 'Genetic Markers', 'Humans', 'Male', 'Meningeal Neoplasms', 'Meningioma', 'Middle Aged', 'Neurofibromatosis 1', 'Neuroma, Acoustic', 'Pedigree'] | 3,134,615 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.284.187.520.300.505.515', 'G05.360.162.520.300.505.515'], ['C04.557.465.625.600.380.290', 'C04.557.470.670.380.290', 'C04.557.580.625.600.380.290'], ['G05.348'], ['D23.101.387'... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The importance of pericentric inversions in the karyotypic diversification of the species Loricariichthys anus and Loricariichthys platymetopon. | Catfishes of the genus Loricariichthys are widely distributed in the Platina Basin. Considering that the cytogenetic knowledge of Loricariichythys is underestimated, this study assessed Loricariichthys anus and Loricariichthys platymetopon through different chromosome bandings, to define the mechanisms determining the ... | ['Animals', 'Biological Evolution', 'Brazil', 'Catfishes', 'Chromosome Inversion', 'Cytogenetic Analysis', 'Female', 'Karyotype', 'Male', 'Species Specificity'] | 24,941,174 | [['B01.050'], ['G05.045', 'G16.075'], ['Z01.107.757.176'], ['B01.050.150.900.493.080'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['G05.360.162.679'], ['G16.824']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
DNA translocation mechanism of an XPD family helicase. | The XPD family of helicases, that includes human disease-related FANCJ, DDX11 and RTEL1, are Superfamily two helicases that contain an iron-sulphur cluster domain, translocate on ssDNA in a 5'-3' direction and play important roles in genome stability. Consequently, mutations in several of these family members in eukary... | ['Adenosine Triphosphate', 'Crystallography, X-Ray', 'DEAD-box RNA Helicases', 'DNA Helicases', 'DNA Repair', 'DNA, Single-Stranded', 'DNA-Binding Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Fanconi Anemia Complementation Group Proteins', 'Humans', 'Iron-Sulfur Proteins', 'RNA Helicases'] | 30,520,735 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['E05.196.309.742.225'], ['D08.811.913.696.445.735.720.249'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['G02.111.222', 'G05.219'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D12.776.260'], ['B03.440.450.425.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-emissive colour filters for fluorescence detection. | We describe a simple technique for fabricating non-emissive colour filters based on the sensitisation of a highly porous nanostructured metal-oxide film with a monolayer of dye molecules. Ultrafast electron transfer at the oxide/dye interface induces efficient quenching of photogenerated excitons in the dye, reducing t... | ['Color', 'Fluorescent Dyes', 'Glass', 'Nanostructures', 'Porosity', 'Spectrometry, Fluorescence', 'Titanium'] | 21,350,748 | [['G01.590.540.199'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['J01.637.437'], ['J01.637.512'], ['G01.374.710'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Distribution of cervical lesions in young and older women. | INTRODUCTION: Age range for cervical screening varies widely between countries. In addition, sexual behavior has changed, life expectancy is increasing, and new insights have been gained into the pathogenesis of HPV infection. Our aim is to evaluate the distribution of cervical lesions in young and older patients.METHO... | ['Adult', 'Age Factors', 'Aged', 'Carcinoma', 'Female', 'Humans', 'Incidence', 'Middle Aged', 'Spain', 'Uterine Cervical Dysplasia', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 31,184,808 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['Z01.542.846'], ['C04.834.818', 'C1... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A simplified state-space model of biventricular assist device-cardiovascular system interaction. | A simplified state-space model of biventricular assist device (BiVAD)-cardiovascular system (CVS) interaction is presented. The state-space equations includes a six-compartments CVS model incorporating the ventricles, the pulmonary and systemic circulations as well as the non-linear behavior of the valve flow, together... | ['Algorithms', 'Arterial Pressure', 'Heart Ventricles', 'Heart-Assist Devices', 'Hemodynamics', 'Humans', 'Models, Cardiovascular'] | 28,325,006 | [['G17.035', 'L01.224.050'], ['G09.330.380.076.347'], ['A07.541.560'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Dynamic performance of vibration induced anterior-posterior sway during upright posture in normal subjects. | Human postural control works as a dynamic feedback control system. The dynamic performance of postural control for anterior-posterior movements during upright posture are defined by three parameters. These parameters reflect the stiffness, the damping and the swiftness of a response to an induced perturbation. In the p... | ['Adolescent', 'Adult', 'Feedback', 'Humans', 'Middle Aged', 'Postural Balance', 'Posture', 'Vibration', 'Vision, Ocular'] | 2,635,508 | [['M01.060.057'], ['M01.060.116'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G11.427.695'], ['G01.374.930'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964... | ['Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Apple Tree Dental: An Innovative Oral Health Solution. | The Surgeon General's Report on Oral Health called attention to the "silent epidemic" of dental disease. Older adults and other vulnerable people continue to suffer disproportionately from dental disease and inadequate access to care. As a society and as dental professionals, we face multiple challenges to care for our... | ['Aged', 'Child', 'Community Health Services', 'Community-Institutional Relations', 'Comprehensive Dental Care', 'Cooperative Behavior', 'Dental Care', 'Dental Care for Aged', 'Dental Care for Children', 'Dental Care for Chronically Ill', 'Dental Care for Disabled', 'Financial Support', 'Health Services Accessibility',... | 26,357,816 | [['M01.060.116.100'], ['M01.060.406'], ['N02.421.143'], ['N04.452.822.210'], ['N04.590.233.250'], ['F01.145.813.115'], ['E06.170', 'N02.421.240.190'], ['E06.170.100', 'N02.421.240.190.210'], ['E06.170.152', 'N02.421.240.190.215'], ['E06.170.205', 'N02.421.240.190.220'], ['E06.170.310', 'N02.421.240.190.230'], ['N03.219... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Genetic structure of a unique admixed population: implications for medical research. | STATEMENT: In naming population groups, we think a chief aim is to use terms that the group members use themselves, or find familiar and comfortable. The terms used in this manuscript to describe populations are as historically correct as possible and are chosen so as not to offend any population group. Two of the auth... | ['Biomedical Research', 'Continental Population Groups', 'Female', 'Genetic Variation', 'Genetics, Population', 'Humans', 'Male', 'Polymorphism, Single Nucleotide'] | 19,892,779 | [['H01.770.644.145'], ['M01.686.508'], ['G05.365'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.598']] | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of 'Alma's' death on women attending for a cervical smear: a questionnaire survey. | Following a story line in Coronation Street in which 'Alma' died of cervical cancer there was a large increase in the number of cervical smears taken in Manchester. To ascertain the extent to which women were influenced to attend for smears by this story line and why, we carried out a postal survey. Our results show th... | ['Adult', 'Drama', 'England', 'Female', 'Health Care Surveys', 'Humans', 'Mass Screening', 'Persuasive Communication', 'Surveys and Questionnaires', 'Television', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 12,546,208 | [['M01.060.116'], ['K01.517.333'], ['Z01.542.363.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.... | ['Named Groups [M]', 'Humanities [K]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
A foreign body in the heart due to an unusual injury. | Penetrating heart injuries are immediate life-threatening situations. We present a case report of a 44-year-old man with a foreign body in his right heart. The injury happened while the man was working with a circular saw 15 months prior to the actual diagnosis. With respect to the size of the foreign body, its close p... | ['Adult', 'Coronary Angiography', 'Coronary Vessels', 'Echocardiography', 'Foreign Bodies', 'Granuloma, Foreign-Body', 'Heart Arrest, Induced', 'Heart Injuries', 'Heart Ventricles', 'Humans', 'Male', 'Metals', 'Postoperative Complications', 'Reoperation', 'Tricuspid Valve', 'Wounds, Penetrating'] | 19,699,935 | [['M01.060.116'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['A07.015.114.269', 'A07.015.908.194'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C26.392'], ['C23.550.382.437', 'C26.392.560.325'], ['E04.100.376.374', 'E04.928.220.360'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Control of zinc-thionein synthesis in rat liver. | The rate of [35S]cystine incorporation into hepatic zinc-thionein (a metallothionein) was stimulated, with a maximum of 5-6h, after parenteral administration of 2mg of Zn2+ containing 65Zn. The binding of 65Zn to zinc-thionein was measurable by 2-1/2h and reached a plateau by 18h after the injection. A net increase in ... | ['Animals', 'Cystine', 'Cytosol', 'Dactinomycin', 'Deoxyadenosines', 'Liver', 'Male', 'Metalloproteins', 'Metallothionein', 'Rats', 'Time Factors', 'Zinc'] | 301,740 | [['B01.050'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['D03.633... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical and social differences between French and migrant patients consulting for the first time for HIV infection. | The objectives of the study were to describe the medical and social characteristics of patients consulting for the first time after diagnosis of HIV-infection and to compare the medical and social characteristics between French and migrant patients. From 1 January 2001 to 31 December 2002, all consecutive adults consul... | ['Adult', 'Analysis of Variance', 'Chi-Square Distribution', 'European Continental Ancestry Group', 'Female', 'France', 'HIV Infections', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Socioeconomic Factors', 'Transients and Migrants'] | 16,036,237 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.686.508.400'], ['Z01.542.286'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sugars and satiety: does the type of sweetener make a difference? | BACKGROUND: Widespread use of high-fructose corn syrup (HFCS) in beverages has been linked to rising obesity rates. One hypothesis is that HFCS in beverages has little satiating power.OBJECTIVE: The objective of the study was to compare the relative effect of commercial beverages containing sucrose or HFCS on hunger, s... | ['Adult', 'Beverages', 'Energy Intake', 'Female', 'Fructose', 'Humans', 'Hunger', 'Male', 'Satiety Response', 'Statistics, Nonparametric', 'Sucrose', 'Thirst'] | 17,616,770 | [['M01.060.116'], ['G07.203.100', 'J02.200'], ['G07.203.650.240.340'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.293.391', 'G07.203.650.390', 'G10.261.390'], ['F02.830.749.658'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.850.520.830.995'], ['D09.698... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
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