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Differences in 100-m sprint performance and skeletal muscle mass between elite male and female sprinters. | BACKGROUND: The sex difference in 100-m sprint performance between the world's best athletes is approximately 10%. We hypothesized that skeletal muscle mass (SM) relative to body mass may be a major factor contributing to this difference. The aim of this study was to examine the sex difference in absolute and relative ... | ['Female', 'Humans', 'Male', 'Muscle, Skeletal', 'Running', 'Sex Factors'] | 29,327,827 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567', 'A10.690.552.500'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['N05.715.350.675', 'N06.850.490.875']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Confocal microscopy in ocular argyrosis. | PURPOSE: To identify the presence of silver deposits in the cornea using a new-generation confocal microscopy technique.METHODS: Case report.RESULTS: A 70-year-old man, who had been a jeweler for many years, was referred to our center for assessment of corneal opacity and ocular pigmentation. Slit-lamp examination reve... | ['Aged', 'Argyria', 'Bowman Membrane', 'Corneal Diseases', 'Corneal Stroma', 'Descemet Membrane', 'Humans', 'Male', 'Microscopy, Confocal', 'Occupational Diseases', 'Occupational Exposure'] | 20,335,809 | [['M01.060.116.100'], ['C17.800.621.166', 'C25.723.522.313'], ['A09.371.060.217.113'], ['C11.204'], ['A09.371.060.217.228'], ['A09.371.060.217.271', 'A10.615.179.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'], ['C24'], ['N06.850.460.350.600']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predictors and causes of unplanned re-operations in outpatient plastic surgery: a multi-institutional analysis of 6749 patients using the 2011 NSQIP database. | Studies that evaluate the predictors and causes of unplanned re-operation in outpatient plastic surgery. This study retrospectively reviewed the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) and identified all plastic surgery outpatient cases performed in 2011. Multiple logistic... | ['Adult', 'Ambulatory Surgical Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Quality Improvement', 'Quality Indicators, Health Care', 'Reconstructive Surgical Procedures', 'Reoperation', 'Risk Assessment'] | 24,533,745 | [['M01.060.116'], ['E04.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['J01.293.754', 'N04.761.744'], ['N04.761.789', 'N05.715.760'], ['E04.680'], ['E04.690'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Proteomic analysis of Bifidobacterium longum subsp. infantis reveals the metabolic insight on consumption of prebiotics and host glycans. | Bifidobacterium longum subsp. infantis is a common member of the intestinal microbiota in breast-fed infants and capable of metabolizing human milk oligosaccharides (HMO). To investigate the bacterial response to different prebiotics, we analyzed both cell wall associated and whole cell proteins in B. infantis. Protein... | ['Bacterial Proteins', 'Bifidobacterium', 'Carbohydrate Metabolism', 'Chromatography, High Pressure Liquid', 'Polysaccharides', 'Prebiotics', 'Proteomics', 'Tandem Mass Spectrometry'] | 23,469,017 | [['D12.776.097'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['G02.111.158', 'G03.191'], ['E05.196.181.400.300'], ['D09.698'], ['D09.301.416.500', 'D09.698.718.622', 'G07.203.300.400.500', 'G07.203.300.456.249', 'J02.500.400.500', 'J02.500.456.249'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A genome triplication associated with early diversification of the core eudicots. | BACKGROUND: Although it is agreed that a major polyploidy event, gamma, occurred within the eudicots, the phylogenetic placement of the event remains unclear.RESULTS: To determine when this polyploidization occurred relative to speciation events in angiosperm history, we employed a phylogenomic approach to investigate ... | ['Evolution, Molecular', 'Gene Duplication', 'Gene Expression Profiling', 'Genetic Speciation', 'Genome, Plant', 'Magnoliopsida', 'Phylogeny', 'Plant Proteins', 'Polyploidy'] | 22,280,555 | [['G05.045.250', 'G16.075.250'], ['G05.365.590.320', 'G05.558.320'], ['E05.393.332'], ['G05.045.350', 'G16.075.350'], ['G05.360.340.365'], ['B01.650.940.800.575.912.250'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D12.776.765'], ['C23.550.210.702', 'G05.365.590.175.677', 'G05.700.740']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Results of community deliberation about social impacts of ecological restoration: comparing public input of self-selected versus actively engaged community members. | Participatory processes for obtaining residents' input about community impacts of proposed environmental management actions have long raised concerns about who participates in public involvement efforts and whose interests they represent. This study explored methods of broad-based involvement and the role of deliberati... | ['Community Participation', 'Conservation of Natural Resources', 'Decision Making', 'Ecology', 'Engineering', 'Female', 'Humans', 'Male', 'Middle Aged', 'Northwestern United States', 'Role', 'Social Change', 'Water Supply'] | 22,615,108 | [['N02.421.143.212', 'N03.540.245.360'], ['J01.256', 'N06.230.080'], ['F02.463.785.373'], ['H01.158.273.248', 'H01.277.249'], ['J01.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.567.875.560'], ['F01.829.316.616'], ['I01.076.201.450.776', 'I01.880.853.400', 'N01.824.737'], ['J01.... | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. | The molecular mechanisms that control the range and stability of emotions are unknown, yet this knowledge is critical for understanding mood disorders, especially bipolar illness. Here, we show that the glucocorticoid receptor (GR) modulates these features of emotional responsiveness. We generated transgenic mice overe... | ['Affective Symptoms', 'Animals', 'Antidepressive Agents', 'Anxiety', 'Cocaine', 'Corticotropin-Releasing Hormone', 'Depression', 'Gene Expression Regulation', 'Membrane Transport Proteins', 'Mice', 'Mice, Transgenic', 'Models, Animal', 'Mood Disorders', 'Prosencephalon', 'Receptor, Serotonin, 5-HT1A', 'Receptors, Gluc... | 15,280,545 | [['F01.145.126.100'], ['B01.050'], ['D27.505.954.427.700.122'], ['F01.470.132'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['F01.145.126.350'], ['G05.308'], [... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of the subunits of beta-conglycinin. | Four subunits of beta-conglycinin were purified from soybean cultivar CX 635-1-1-1, and were designated alpha, alpha', beta, and beta' in accordance with nomenclature proposed by Thanh and Shibasaki [(1977) Biochim. Biophys. Acta 490, 370-384]. Of these subunits, beta' has not previously been reported or characterized.... | ['Amino Acid Sequence', 'Amino Acids', 'Antigens, Plant', 'Base Sequence', 'Carbohydrates', 'Chromatography, Ion Exchange', 'Cyanogen Bromide', 'DNA', 'Electrophoresis, Polyacrylamide Gel', 'Globulins', 'Macromolecular Substances', 'Methionine', 'Peptide Fragments', 'Seed Storage Proteins', 'Soybean Proteins', 'Soybean... | 3,840,670 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['D23.050.291'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D09'], ['E05.196.181.400.383'], ['D01.139.300.050.100', 'D01.625.175'], ['D13.444.308'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.377'], ['D05'], ['D02.886.030.676', 'D12.125.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
A quality assurance tool for high-dose-rate brachytherapy. | PURPOSE: The purpose of this work was to develop a quality assurance (QA) tool for high-dose-rate (HDR) brachytherapy that would quickly and easily verify both source positioning (dwell positions) and durations (dwell times).METHODS: The authors constructed a QA tool that combined radiochromic film to verify position w... | ['Algorithms', 'Brachytherapy', 'Canada', 'Film Dosimetry', 'Quality Assurance, Health Care', 'Radiotherapy Dosage', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 20,632,564 | [['G17.035', 'L01.224.050'], ['E02.815.150'], ['Z01.107.567.176'], ['E05.799.638.420', 'N06.850.810.370.310'], ['N04.761.700', 'N05.700'], ['E02.815.639'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Enhanced expression of cyclooxygenase-2 in glaucomatous dog eyes. | OBJECTIVE: Cyclooxygenase-2 (COX-2)-derived prostaglandins (PGs) are shown to play important pathophysiologic roles in various disease states. Recently, the effectiveness of topical PGs in reducing intraocular pressure (IOP) has stimulated further interest in the physiologic function of COX-2 and PGs in normal and glau... | ['Animals', 'Anterior Eye Segment', 'Case-Control Studies', 'Cyclooxygenase 2', 'Dog Diseases', 'Dogs', 'Female', 'Glaucoma', 'Immunohistochemistry', 'Isoenzymes', 'Male', 'Prostaglandin-Endoperoxide Synthases'] | 14,738,509 | [['B01.050'], ['A09.371.060'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D08.811.600.720.750'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C11.525.381'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Starch molecular structure shows little association with fruit physiology and starch metabolism in tomato. | The aim of this work was to determine if the molecular structure of starch from tomato ( Solanum lycopersicum L.) is influenced by fruit physiology and carbohydrate metabolism. The effect of fruit size, fruit ripening behavior, and assimilate availability on starch granule accumulation was examined in nine tomato sampl... | ['Amylose', 'Fruit', 'Lycopersicon esculentum', 'Molecular Structure', 'Starch'] | 20,038,101 | [['D09.301.915.361', 'D09.698.365.855.361'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.650.940.800.575.912.250.908.500.322'], ['G02.111.570', 'G02.466'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Soluble CD59 expressed from an adenovirus in vivo is a potent inhibitor of complement deposition on murine liver vascular endothelium. | Inappropriate activation of complement on the vascular endothelium of specific organs, or systemically, underlies the etiology of a number of diseases. These disorders include atypical hemolytic uremic syndrome, membranoproliferative glomerulonephritis, atherosclerosis, age-related macular degeneration, diabetic retino... | ['Adenoviridae', 'Animals', 'Antibodies', 'Aorta', 'Blood Vessels', 'CD59 Antigens', 'Complement Activation', 'Complement Membrane Attack Complex', 'Endothelial Cells', 'Endothelium, Vascular', 'Humans', 'Injections, Intraperitoneal', 'Liver', 'Mice', 'Mice, Inbred C57BL', 'Organ Specificity', 'Platelet Endothelial Cel... | 21,720,565 | [['B04.280.030'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A07.015.114.056'], ['A07.015'], ['D12.776.395.550.448.140', 'D12.776.543.484.500.140', 'D12.776.543.550.418.140'], ['G12.274'], ['D12.776.124.486.274.930'], ['A11.436.275'], ['A07.015.700.500', 'A10.272.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A simulation study of the efficacy of stepwise discriminant analysis in the detection and comparison of event related potentials. | Cortical average evoked potentials were simulated by summing five damped sinusoids. The characteristics of these "evoked" responses could be manipulated by changing parameters of the sinusoids. The synthesized signals were mixed with noise processes whose power and band-width were manipulated. Thus data were generated ... | ['Electroencephalography', 'Evoked Potentials', 'Humans', 'Mathematics', 'Models, Neurological', 'Photic Stimulation', 'Statistics as Topic', 'Time Factors', 'Visual Perception'] | 45,904 | [['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['E05.599.395.642'], ['E05.723.729'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830'], ['G01.910.857'], ['F02.463.593.932']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Surgical management of patients with progressing metastatic gastrointestinal stromal tumors receiving sunitinib treatment: A prospective cohort study. | BACKGROUND: For selected patients with metastatic gastrointestinal stromal tumor (GIST) who have received first-line imatinib (IM) and are undergoing cytoreductive surgery, response to IM at time of surgery correlates with resection completeness as well as favorable progression-free survival (PFS) and overall survival ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Combined Modality Therapy', 'Cytoreduction Surgical Procedures', 'Disease Progression', 'Disease-Free Survival', 'Female', 'Gastrointestinal Neoplasms', 'Gastrointestinal Stromal Tumors', 'Humans', 'Indoles', 'Male', 'Middle Aged', 'Mutation... | 28,110,026 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E02.186'], ['E04.166'], ['C23.550.291.656'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C04.588.274.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical experience with a new recombinant hepatitis-B vaccine in previous non-responders with chronic renal insufficiency. | Patients with renal insufficiency have an increased risk of hepatitis B infection and a high probability to develop a chronic course of this disease. After hepatitis B vaccination they are known to show a low rate of seroconversion. In the present study we assessed the efficacy of a new recombinant pre-S1 and pre-S2 co... | ['Adult', 'Aged', 'Female', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Vaccines', 'Hepatitis B virus', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Risk Factors', 'Vaccination', 'Vaccines, Synthetic'] | 8,706,359 | [['M01.060.116'], ['M01.060.116.100'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.715.548.114.254.450.504'], ['D20.215.894.899.955.400'], ['B04.280.375.650.425', 'B04.450.390.650.425'],... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Construction of N-halamine labeled silica/zinc oxide hybrid nanoparticles for enhancing antibacterial ability of Ti implants. | The traditional antibiotic treatment for bacterial infections often induces antibiotic resistance in bacteria. In this work, we developed hybrid nanoparticles (NPs) with a self-antibacterial ability on Ti implants using monodispersed polystyrene-acrylic acid (PSA) nanoparticles as colloidal templates followed by the el... | ['Anti-Bacterial Agents', 'Escherichia coli', 'Metal Nanoparticles', 'Microbial Sensitivity Tests', 'Silicon Dioxide', 'Staphylococcus aureus', 'Zinc Oxide'] | 28,482,556 | [['D27.505.954.122.085'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['J01.637.512.600.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Hepatitis B virus vaccination of blood donors--what costs may be expected? | Although the risk of transfusion-transmitted hepatitis B virus (TT-HBV) infection is very low, it still exists. Therefore, introduction of further precautions to reduce this risk is discussed at present. However, so far no data are available about the HBV vaccination status among blood donors (BDs). We compared HBV vac... | ['Adult', 'Blood Donors', 'Blood Transfusion', 'Female', 'Hepatitis B', 'Hepatitis B Vaccines', 'Hepatitis B virus', 'Humans', 'Male', 'Vaccination'] | 15,859,973 | [['M01.060.116'], ['M01.898.313'], ['E02.095.135'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D20.215.894.899.955.400'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gas-liquid chromatography and infrared spectroscopy of resmethrin in nonaqueous aerosols. | Two rapid and precise methods have been developed for the determination of resmethrin in nonaqueous aerosol formulations. The propellents are evaporated, the residue is dissolved in carbon disulfide, and the resulting solution is analyzed by gas-liquid chromatography or infrared spectroscopy. The accuracies of the meth... | ['Aerosols', 'Chromatography, Gas', 'Chromatography, Liquid', 'Chrysanthemum cinerariifolium', 'Pyrethrins', 'Spectrophotometry, Infrared', 'Time Factors'] | 939,739 | [['D20.280.055', 'D26.255.165.055'], ['E05.196.181.349'], ['E05.196.181.400'], ['B01.650.940.800.575.912.250.100.206.222'], ['D02.455.849.575.188.750'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Processing circadian data collected from the Drosophila Activity Monitoring (DAM) System. | Adult behavioral assays have been used with great success in Drosophila melanogaster to identify circadian rhythm genes. In particular, the locomotor activity assay can identify altered behavior patterns over the course of several days in small populations, or even individual flies. Generally, circadian behavior is ass... | ['Animals', 'Circadian Rhythm', 'Drosophila melanogaster', 'Entomology', 'Motor Activity'] | 21,041,392 | [['B01.050'], ['G07.180.562.190'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['H01.158.273.943.409'], ['F01.145.632', 'G11.427.410.698']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Designed amino acid ATRP initiators for the synthesis of biohybrid materials. | A synthetic strategy to prepare peptide-polymer conjugates with precise sites of attachment is described. Amino acids modified with atom transfer radical polymerization (ATRP) initiators for the polymerization of styrenes and methacrylates were prepared. Fmoc-4-(1-chloroethyl)-phenylalanine (5) was synthesized in four ... | ['Amino Acids', 'Dipeptides', 'Fluorenes', 'Methacrylates', 'Peptides', 'Phenylalanine', 'Polymers', 'Polymethacrylic Acids', 'Polystyrenes', 'Serine', 'Styrenes'] | 18,161,975 | [['D12.125'], ['D12.644.456.345'], ['D02.455.426.559.847.389', 'D04.615.389'], ['D02.241.081.069.600'], ['D12.644'], ['D12.125.072.050.685', 'D12.125.142.666'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D02.241.081.069.800', 'D05.750.716.822.111.650', 'D25.720.716.822.111.650', 'J01.637.051.720.716.822.111.650'], ['... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Actomyosin promotes cell plate alignment and late lateral expansion in Tradescantia stamen hair cells. | Cytokinesis in higher-plant cells involves the formation of a cell plate in the interzone between the separating chromatids. The process is directed by the phragmoplast, an array of microtubules, actin filaments, and membranous elements. To determine if the role of actin in cytokinesis is dependent on myosin, we treate... | ['Actins', 'Actomyosin', 'Azepines', 'Calcium', 'Cell Division', 'Cytoplasmic Streaming', 'Diacetyl', 'Magnoliopsida', 'Myosins', 'Naphthalenes', 'Plant Structures'] | 11,882,936 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D12.776.210.500.154'], ['D03.383.066'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G03.143.355', 'G04.392'], ['D02.522.296.400'], ['B01.650.940.800.575.912.25... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prediction of Protein Coding Regions Using a Wide-Range Wavelet Window Method. | Prediction of protein coding regions is an important topic in the field of genomic sequence analysis. Several spectrum-based techniques for the prediction of protein coding regions have been proposed. However, the outstanding issue in most of the proposed techniques is that these techniques depend on an experimentally-... | ['Genomics', 'Models, Statistical', 'Open Reading Frames', 'Proteins', 'Sequence Analysis, DNA', 'Wavelet Analysis'] | 26,415,183 | [['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['D12.776'], ['E05.393.760.700'], ['E05.959', 'G17.915', 'L01.224.800.750']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Alternative pathway for complement activation triggered by human liver plasma membranes. | Liver plasma membranes (LPM) prepared from normal hepatocytes by centrifugation in sucrose discontinuous gradient, are capable of haemolysing PNH-like cells in the presence of complement or complement plus EGTA or MG2+ ions. In contrast, EDTA or Ca2+ ions inhibit the lysis. The total complement lytic activity is reduce... | ['Cell Membrane', 'Centrifugation, Density Gradient', 'Complement Activation', 'Complement C4', 'Complement Pathway, Alternative', 'Humans', 'Immunoelectrophoresis, Two-Dimensional', 'Immunologic Techniques', 'Liver', 'Liver Diseases', 'Sucrose'] | 7,024,075 | [['A11.284.149'], ['E05.181.724.336', 'E05.196.941.336'], ['G12.274'], ['D12.776.124.486.274.350'], ['G12.274.695'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350.350.350', 'E05.196.401.568.520', 'E05.200.812.735.645.350.350.350', 'E05.301.300.568.520', 'E05.478.594.760.645.350.350.350'... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of humidity on hyperoxic toxicity. | Time to onset of hyperbaric oxygen-induced convulsions was measured in mice and rats exposed to hyperbaric oxygen (515-585 kPa) under conditions of low humidity (dry gas, < 10% relative humidity) or in a humidified environment (60% relative humidity). At all pressures tested, the duration of convulsive activity was mar... | ['Animals', 'Body Temperature', 'Humidity', 'Hyperbaric Oxygenation', 'Lung Diseases', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Organ Size', 'Oxygen', 'Rats', 'Rats, Wistar', 'Seizures'] | 8,307,849 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['E02.880.690.490'], ['C08.381'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['E01.370... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The importance of field experiments in testing of sensors for dietary assessment and eating behavior monitoring. | The field of sensor-based dietary assessment and behavioral monitoring is rapidly expanding. New devices and methods for detection for food intake and characterization of ingestive behavior, energy intake and nutrition have been introduced. Quite often the testing of new devices is limited to restricted meals in labora... | ['Diet', 'Eating', 'Energy Intake', 'Feeding Behavior', 'Humans', 'Meals', 'Nutrition Assessment', 'Video Recording', 'Wearable Electronic Devices'] | 30,441,644 | [['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.650.240.340'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.590', 'J02.500.590'], ['E05.318.308.585', 'N05.715.360.300.560', 'N06.850.505.557', 'N06.850.520.308.585'], ['L01.280.9... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[Bone tunnel fixation versus suture anchor: mid- and long-term results after distal biceps tendon rupture]. | AIM: The aim of this study was to assess the range of movement, isometric and isokinetic postoperative outcome, Morrey score and heterotropic ossifications after refixation of distal biceps tendon rupture with either suture anchor or bone tunnel fixation.METHODS: 48 patients were surgically treated between 1990 and 200... | ['Adult', 'Aged', 'Elbow Joint', 'Female', 'Follow-Up Studies', 'Humans', 'Isometric Contraction', 'Male', 'Middle Aged', 'Ossification, Heterotopic', 'Postoperative Complications', 'Range of Motion, Articular', 'Recurrence', 'Retrospective Studies', 'Rupture', 'Suture Anchors', 'Tendon Injuries', 'Tenodesis'] | 17,559,023 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.583.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['M01.060.116.630'], ['C23.550.751'], ['C23.550.767'], ['E01.370.600.700', 'G11.427.760'], ['C23.55... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Methodological Considerations for Advancing Research on the Health and Wellbeing of Sexual and Gender Minority Youth. | Continued research with sexual and gender minority (SGM) youth is essential both to understand health disparities and to develop interventions targeting those disparities, but conducting rigorous, ethical research with these populations remains a substantial challenge. In addition to considerations for research with ad... | ['Adolescent', 'Biomedical Research', 'Child Welfare', 'Female', 'Humans', 'Male', 'Research Design', 'Sexual and Gender Minorities'] | 31,145,662 | [['M01.060.057'], ['H01.770.644.145'], ['I01.880.787.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500', 'H01.770.644.728'], ['M01.777']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness. | BACKGROUND: CRF02_AG is the predominant HIV strain circulating in West and West Central Africa. The aim of this study was to test whether this predominance is associated with a higher in vitro replicative fitness relative to parental subtype A and G viruses. Primary HIV-1 isolates (10 CRF02_AG, 5 subtype A and 5 subtyp... | ['CD4-Positive T-Lymphocytes', 'Cameroon', 'Cells, Cultured', 'Cohort Studies', 'Dendritic Cells', 'HIV Infections', 'HIV-1', 'Humans', 'Phylogeny', 'Sequence Analysis, RNA', 'Virus Replication'] | 16,817,969 | [['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['Z01.058.290.100.110'], ['A11.251'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C01.221.250.875', 'C01.221.812.... | ['Anatomy [A]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Rape, sex partnership, and substance use consequences in women veterans. | The association of rape history and sexual partnership with alcohol and drug use consequences in women veterans is unknown. Midwestern women veterans (N = 1,004) completed a retrospective telephone interview assessing demographics, rape history, substance abuse and dependence, depression, and posttraumatic stress disor... | ['Adult', 'Cohort Studies', 'Female', 'Humans', 'Interviews as Topic', 'Middle Aged', 'Rape', 'Retrospective Studies', 'Sexual Partners', 'Stress Disorders, Post-Traumatic', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'United States', 'Veterans', 'Young Adult'] | 21,567,476 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['I01.198.240.748.640', 'I01.198.240.856.744', 'I01.880.735.900.772... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Association of common variants in NOS1AP gene with sudden unexplained nocturnal death syndrome in the southern Chinese Han population. | Here, we investigate the association of common polymorphisms of the NOS1AP gene with sudden unexplained nocturnal death syndrome (SUNDS) in the southern Chinese Han population. We genetically screened five common NOS1AP polymorphisms (rs10918594, rs12143842, rs16847548, rs12567209, and rs10494366) previously reported t... | ['Adaptor Proteins, Signal Transducing', 'Adolescent', 'Adult', 'Alleles', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'China', 'Death, Sudden', 'Ethnic Groups', 'Genotype', 'Haplotypes', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Young Adult'] | 24,504,561 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.057'], ['M01.060.116'], ['G05.360.340.024.340.030'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.252.474.164'], ['C23.550.260.322'], ['M01.686.754', 'N01.224.317'], ['G05.380'], ['G05.380.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ca(2+)-dependent inhibition of inwardly rectifying K(+) channel in opossum kidney cells. | The effect of intracellular Ca(2+) on the activity of the inwardly rectifying ATP-regulated K(+) channel with an inward conductance of about 90 pS was examined by using the patch-clamp technique in opossum kidney proximal tubule (OKP) cells. The activity of the inwardly rectifying K(+) channel rapidly declined with an ... | ['Adenosine Triphosphate', 'Animals', 'Calcineurin', 'Calcium', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Calmodulin', 'Cell Culture Techniques', 'Electrophysiology', 'Kidney Tubules, Proximal', 'Opossums', 'Patch-Clamp Techniques', 'Phosphorylation', 'Potassium Channels', 'Protein Kinase C'] | 11,492,962 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['D12.644.360.372.249', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of elevated dissolved carbon dioxide and perfluorooctane sulfonic acid, given singly and in combination, on steroidogenic and biotransformation pathways of Atlantic cod. | In the aquatic environments, the predicted changes in water temperature, pO2 and pCO2 could result in hypercapnic and hypoxic conditions for aquatic animals. These conditions are thought to affect several basic cellular and physiological mechanisms. Yet, possible adverse effects of elevated CO2 (hypercapnia) on teleost... | ['Alkanesulfonic Acids', 'Animals', 'Carbon Dioxide', 'Endocrine Disruptors', 'Fluorocarbons', 'Gadus morhua', 'Gonadal Steroid Hormones', 'RNA, Messenger', 'Reproducibility of Results', 'Water Pollutants, Chemical'] | 25,063,886 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D27.505.696.353', 'D27.888.141'], ['D02.455.526.510.435'], ['B01.050.150.900.493.467.400'], ['D06.472.334.851'], ['D13.444.735.544'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of human embryonic stem cell-derived hepatocyte-like cells for detection of CYP1A inducers. | There is a great deal of interest in differentiation of human embryonic stem cells (hESCs) into hepatocyte-like cells for application in pharmaceutical screening. Cytochrome P450 (CYP) 1A is involved in the metabolic activation of procarcinogenic compounds as well as in detoxification of drugs. We differentiated hESCs ... | ['Adult', 'Albumins', 'Animals', 'Biotransformation', 'Cell Differentiation', 'Cell Line', 'Cytochrome P-450 CYP1A1', 'Cytochrome P-450 CYP1A2', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 Enzyme System', 'Drug Discovery', 'Embryonic Stem Cells', 'Enzyme Induction', 'Glucuronosyltransferase', 'Hepatocytes', 'Humans', '... | 22,673,034 | [['M01.060.116'], ['D12.776.034'], ['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['G04.152'], ['A11.251.210'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.220.453.010.332', 'D12.776.422.220.453.100.500'], ['D08.244.453.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Penalized probabilistic clustering. | While clustering is usually an unsupervised operation, there are circumstances in which we believe (with varying degrees of certainty) that items A and B should be assigned to the same cluster, while items A and C should not. We would like such pairwise relations to influence cluster assignments of out-of-sample data i... | ['Algorithms', 'Artifacts', 'Cluster Analysis', 'Models, Statistical', 'Pattern Recognition, Automated'] | 17,444,759 | [['G17.035', 'L01.224.050'], ['E05.047'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['L01.399.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Hyperglycaemia following glucose challenge test during pregnancy: when can a screening test become diagnostic? | OBJECTIVE: The 50g-glucose challenge test (GCT) is commonly used for screening of gestational diabetes (GDM) in low risk pregnant women. If elevated, glucose tolerance test is performed to confirm the diagnosis. In this study, we evaluated whether GCT alone is sufficient to diagnose GDM when the GCT result is very elev... | ['Circadian Rhythm', 'Diabetes, Gestational', 'Fasting', 'Female', 'Glucose Tolerance Test', 'Humans', 'Hyperglycemia', 'Mass Screening', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Complications', 'Reproducibility of Results'] | 19,124,172 | [['G07.180.562.190'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['E01.370.500', 'E05.318.308.980.43... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Influence of morbidity and the use of health resources in patients who require care for generalised anxiety disorder in the primary health care setting]. | OBJECTIVE: To evaluate the co-morbidity, health care use, economical impact, and availability of effective treatments used in generalised anxiety disorder (GAD) patients in a primary care setting (PCS).METHOD: A retrospective multicentre population-based study.SETTING: Five primary care clinics managed by Badalona Serv... | ['Adult', 'Aged', 'Anxiety', 'Comorbidity', 'Costs and Cost Analysis', 'Female', 'Health Services', 'Humans', 'Male', 'Middle Aged', 'Primary Health Care', 'Retrospective Studies', 'Spain', 'Young Adult'] | 19,100,147 | [['M01.060.116'], ['M01.060.116.100'], ['F01.470.132'], ['N05.715.350.225', 'N06.850.490.687'], ['N03.219.151'], ['N02.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.590.233.727'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensable. | We have shown that the spt6-140 and spt4-3 mutations, affecting chromatin structure and transcription, stimulate recombination between inverted repeats by a RAD52-dependent mechanism that is very efficient in the absence of RAD51, RAD54, RAD55, and RAD57. Such a mechanism of recombination is RAD1-RAD59-dependent and yi... | ['Blotting, Northern', 'Blotting, Southern', 'Chromatin', 'DNA', 'DNA-Binding Proteins', 'Fungal Proteins', 'Genotype', 'Histone Chaperones', 'Hydro-Lyases', 'Models, Genetic', 'Mutation', 'Nuclear Proteins', 'Rad51 Recombinase', 'Recombination, Genetic', 'Saccharomyces cerevisiae Proteins', 'Transcription, Genetic', '... | 11,404,325 | [['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['D12.776.260'], ['D12.776.354'], ['G05.380'], ['D12.776.580.219'], ['D08.811.520.241.300'], ['E05.599.395.397'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. | Addition of brefeldin A (BFA) to most cells results in both the formation of extensive, uncoated membrane tubules through which Golgi components redistribute into the ER and the failure to transport molecules out of this mixed ER/Golgi system. In this study we provide evidence that suggests BFA's effects are not limite... | ['Animals', 'Biological Transport', 'Brefeldin A', 'Cell Line', 'Coatomer Protein', 'Cyclopentanes', 'Endocytosis', 'Endoplasmic Reticulum', 'Endosomes', 'Fluorescent Antibody Technique', 'Golgi Apparatus', 'In Vitro Techniques', 'Intracellular Membranes', 'Lysosomes', 'Membrane Proteins', 'Microscopy, Electron', 'Micr... | 1,682,055 | [['B01.050'], ['G03.143'], ['D02.540.576.500.875'], ['A11.251.210'], ['D12.776.543.990.300.300'], ['D02.455.426.392.368.450'], ['G04.417'], ['A11.284.430.214.190.875.248'], ['A11.284.430.214.190.875.190.880.337'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The discriminant analysis of the silicosis's induction on cytokines in phlegm and combined multi-markers]. | OBJECTIVE: To investigate the changes of cytokines in induced sputum at different stages of silicosis patients.METHODS: A total of 200 workers from one of the Shandong Province gold mine were chosen as object of observation. Among which 40 patients at silicosis stage I and 40 patients at silicosis stage II were divided... | ['Biomarkers', 'Case-Control Studies', 'Chemokine CCL2', 'Chemokine CCL3', 'Cytokines', 'Discriminant Analysis', 'Dust', 'Humans', 'Interleukin-16', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 9', 'Platelet-Derived Growth Factor', 'Silicosis', 'Sputum', 'Transforming Growth Factor beta', 'Tumor Necrosis Fac... | 26,653,222 | [['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D12.644.276.374.200.110.150', 'D12.644.276.374.200.600.150', 'D12.77... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The epiphyseal spur. | A small spur seen at the edge of an open epiphyseal line indicates the presence of an open epiphysis when this is not clear radiographically. In addition, the spur should not be mistaken for an avulsion fracture. | ['Adolescent', 'Adult', 'Cartilage Diseases', 'Child', 'Epiphyses', 'Female', 'Humans', 'Humerus', 'Male', 'Metacarpus', 'Radiography', 'Radius'] | 7,209,570 | [['M01.060.057'], ['M01.060.116'], ['C05.182', 'C17.300.182'], ['M01.060.406'], ['A02.835.232.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090.400'], ['A01.378.800.667.572'], ['E01.370.350.700'], ['A02.835.232.087.090.700']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of interior lead hazard controls on children's blood lead concentrations: a systematic evaluation. | Dust control is often recommended to prevent children's exposure to residential lead hazards, but the effect of these controls on children's blood lead concentrations is uncertain. We conducted a systematic review of randomized, controlled trials of low-cost, lead hazard control interventions to determine the effect of... | ['Air Pollution, Indoor', 'Child', 'Child Welfare', 'Child, Preschool', 'Cost Control', 'Dust', 'Environmental Exposure', 'Housing', 'Humans', 'Lead Poisoning', 'Odds Ratio', 'Randomized Controlled Trials as Topic'] | 11,781,171 | [['N06.850.460.100.080'], ['M01.060.406'], ['I01.880.787.293'], ['M01.060.406.448'], ['N03.219.151.160'], ['D20.633.222'], ['N06.850.460.350'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.723.522.750'], ['E05.318.740.600.600', 'G17... | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Non-syndromic hypodontia of permanent dentition associated with other dental anomalies in children and adolescents. | Anomalies of permanent dentition, by the frequency of the cases, also correspond to some unanimously recognized problems of public health. The objective of this study is to determine the prevalence of non-syndromic hypodontia and oligodontia and to identify the types of associated dental anomalies in the permanent dent... | ['Adolescent', 'Anodontia', 'Child', 'Dentition, Permanent', 'Female', 'Humans', 'Male', 'Tooth Abnormalities'] | 30,534,829 | [['M01.060.057'], ['C07.650.800.100', 'C07.793.700.100', 'C16.131.850.800.100'], ['M01.060.406'], ['A14.549.167.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.650.800', 'C07.793.700', 'C16.131.850.800']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evidence for a role of N-methyl-D-aspartate receptors in L-arginine-induced attenuation of morphine antinociception. | Twice daily injections of L-arginine (50, 100 or 200 mg/kg, i.p.) for 4 days dose-dependently, decreased morphine antinociception in male Swiss-Webster mice as measured by the tail-flick test. To determine the possible role of N-methyl-D-aspartate (NMDA) receptor in the action of L-arginine, the effects of MK-801, a no... | ['Animals', 'Arginine', 'Dizocilpine Maleate', 'Dose-Response Relationship, Drug', 'Excitatory Amino Acid Antagonists', 'Isoquinolines', 'Male', 'Mice', 'Morphine', 'Narcotics', 'Neuroprotective Agents', 'Nociceptors', 'Receptors, N-Methyl-D-Aspartate', 'Time Factors'] | 9,519,279 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['D03.633.100.531'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.132.577.249.562.571... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Homoacetogenesis in Deep-Sea Chloroflexi | The deep marine subsurface is one of the largest unexplored biospheres on Earth and is widely inhabited by members of the phylum Chloroflexi In this report, we investigated genomes of single cells obtained from deep-sea sediments of the Peruvian Margin, which are enriched in such Chloroflexi 16S rRNA gene sequence anal... | ['Acetates', 'Anaerobiosis', 'Aquatic Organisms', 'Chloroflexi', 'Cluster Analysis', 'DNA, Bacterial', 'DNA, Ribosomal', 'Genome, Bacterial', 'Geologic Sediments', 'Metabolic Networks and Pathways', 'Pacific Ocean', 'Peru', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA'] | 29,259,088 | [['D02.241.081.018', 'D10.251.400.045'], ['G02.111.062', 'G03.078'], ['B05.080', 'G16.500.275.725.500.650.075'], ['B03.275'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.212'], ['D13.444.308.475'], ['G05.360.340.358.207'], ['G01.311.330', 'G16.500.320'], ['G03.493'], ['Z01.756.700']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments. | Ischemia and heart failure are associated with protein kinase C (PKC) dependent phosphorylation of cardiac troponin I (cTnI). We investigated the effect of phosphorylation of cTnI PKC sites S43, S45 and T144 under normal (pH 7.0) and acidic (pH 6.5) conditions on tension in skinned fiber bundles from a mouse heart. To ... | ['Actin Cytoskeleton', 'Animals', 'Calcium', 'Cloning, Molecular', 'Detergents', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Mice', 'Models, Biological', 'Myocytes, Cardiac', 'Phosphorylation', 'Troponin I'] | 19,426,736 | [['A11.284.430.214.190.750.050'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.393.220'], ['D27.720.877.265', 'J01.516.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['A07.541.704.570', 'A10.690.552.750.570'... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Synthesis and biological evaluation of caulibugulones A-E. | The marine bryozoan metabolites caulibugulone A-E were prepared from a readily available isoquinoline dione. These natural products were found to be potent and selective inhibitors of the dual specificity phosphatase Cdc25B. | ['Animals', 'Antineoplastic Agents', 'Bryozoa', 'Enzyme Inhibitors', 'Humans', 'Inhibitory Concentration 50', 'Isoquinolines', 'Quinones', 'Stereoisomerism', 'Structure-Activity Relationship', 'Tumor Cells, Cultured', 'cdc25 Phosphatases'] | 15,280,951 | [['B01.050'], ['D27.505.954.248'], ['B01.050.500.217'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.936.563'], ['D03.633.100.531'], ['D02.806'], ['G02.607.445.682'], ['G02.111.830', 'G07.690.773.997'], ['A11.251.860'], ['D08.811.277.352.650.625.225.100', 'D08.811.277.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The TNFSF15 gene single nucleotide polymorphism rs7848647 is associated with surgical diverticulitis. | OBJECTIVE: To determine if single nuclear polymorphisms (SNPs) in the TFNSF15 gene play a role in patients requiring surgery for diverticulitis.BACKGROUND: A role for a genetic predisposition in diverticulitis is suggested by its association with hereditary connective tissue disorders, youthful onset in some patients, ... | ['Adult', 'Aged', 'Alleles', 'Colectomy', 'Colonic Diseases', 'DNA', 'Diverticulitis', 'Female', 'Follow-Up Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Pedigree', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Retrospective Studies', 'Tumor Necrosis Factor Ligand Super... | 24,814,505 | [['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['E04.210.219'], ['C06.405.469.158'], ['D13.444.308'], ['C06.405.205.282.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
QM/MM modeling of environmental effects on electronic transitions of the FMO complex. | The Fenna-Matthews-Oslon (FMO) light harvesting pigment-protein complex in green sulfur bacteria transfers the excitation energy from absorbed sunlight to the reaction center with almost 100% quantum efficiency. The protein-pigment coupling (part of the environmental effects) is believed to play an important role in de... | ['Electron Transport', 'Light-Harvesting Protein Complexes', 'Molecular Dynamics Simulation', 'Quantum Theory'] | 23,480,507 | [['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', 'D12.776.765.199.750.750.490'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['H01.671.579.800']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Pressure distribution on mattresses. | Measurements of pressure distribution are usually performed on a hard base, such as those in gait analysis or tire research; measurements on soft surfaces are avoided because of technical problems. A sensor mat was developed which consists of 512 pressure sensors, glued to arbitrary locations of a fabric. The mat can b... | ['Beds', 'Biomechanical Phenomena', 'Calibration', 'Computer Graphics', 'Computer Simulation', 'Humans', 'Pressure', 'Skin Physiological Phenomena', 'Somatotypes', 'Spine', 'Weight-Bearing'] | 8,308,053 | [['E07.325.220'], ['G01.154.090', 'G01.374.089'], ['E05.978.155'], ['L01.224.108', 'L01.296.110'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.715'], ['G13.750'], ['E01.370.600.115.800', 'G07.100.800'], ['A02.835.232.834'], ['G01.374.965']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vitro inhibitory effects of tea polyphenols on the proliferation of Chlamydia trachomatis and Chlamydia pneumoniae. | In vitro inhibitory effects of tea polyphenols on Chlamydia trachomatis and C. pneumoniae were investigated. A product of tea polyphenols, Polyphenon 70S was used. Chlamydial strains used were C. trachomatis D/UW-3/Cx and L(2)/434/Bu, and C. pneumoniae AR-39 and AC-43 strains. HeLa229 cells and HL cells were used for c... | ['Chlamydia trachomatis', 'Chlamydophila pneumoniae', 'Dose-Response Relationship, Drug', 'Flavonoids', 'Microbial Sensitivity Tests', 'Phenols', 'Polyphenols', 'Tea'] | 14,583,635 | [['B03.440.190.190.190.750'], ['B03.440.190.190.230.249'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.455.426.559.389.657'], ['D02.455.426.559.389.657.715', 'D03.633.100.150.266.450.260.777'], ['D20... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation? | Lipid-based formulations (LBFs) is a formulation strategy for enabling oral delivery of poorly water-soluble drugs. However, current use of this strategy is limited to a few percent of the marketed products. Reasons for that are linked to the complexity of LBFs, chemical instability of pre-dissolved drug and a limited ... | ['Administration, Oral', 'Animals', 'Bile Acids and Salts', 'Carvedilol', 'Digestion', 'Dogs', 'Drug Delivery Systems', 'Excipients', 'Fatty Acids, Nonesterified', 'Intestinal Absorption', 'Intestinal Secretions', 'Lipids', 'Lipolysis', 'Male', 'Solubility'] | 31,047,962 | [['E02.319.267.100'], ['B01.050'], ['D04.210.500.105'], ['D02.033.100.624.151', 'D02.033.755.624.151', 'D02.092.063.624.151', 'D03.633.100.473.144.125', 'D03.633.300.148.125'], ['G07.203.650.250', 'G10.261.190'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.319.300'], ['D26.650.700.419', 'D27.720.744.770.419'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The right to prevention and the challenges of reducing vulnerability to HIV in Brazil]. | The study evaluates the Brazilian response to the targets established by UNGASS for the prevention of HIV/AIDS. The analysis was based on national research, documents and information from the National Program STD/AIDS and on state-level action plans and targets. Brazil relies on various prevention policies to attain th... | ['AIDS Serodiagnosis', 'Acquired Immunodeficiency Syndrome', 'Adolescent', 'Adult', 'Brazil', 'Condoms', 'Condoms, Female', 'Contraceptive Devices', 'Female', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Health Services Accessibility', 'Human Rights', 'Humans', 'Male', 'National Health Programs', 'Sex Ed... | 16,729,166 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['M01.060.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Differentiating intraprofessional attitudes toward paradigms in health care delivery among chiropractic factions: results from a randomly sampled survey. | BACKGROUND: As health care has increased in complexity and health care teams have been offered as a solution, so too is there an increased need for stronger interprofessional collaboration. However the intraprofessional factions that exist within every profession challenge interprofessional communication through contra... | ['Attitude of Health Personnel', 'Canada', 'Chiropractic', 'Complementary Therapies', 'Data Collection', 'Delivery of Health Care', 'Humans', 'Interprofessional Relations', 'Referral and Consultation', 'Surveys and Questionnaires'] | 24,512,507 | [['F01.100.050', 'N05.300.100'], ['Z01.107.567.176'], ['H02.110'], ['E02.190'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['N04.452.758.849'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Prenatal exposure to a viral mimetic alters behavioural flexibility in male, but not female, rats. | Current understanding of the etiology of neurodevelopmental disorders is limited; however, recent epidemiological studies demonstrate a strong correlation between prenatal infection during pregnancy and the development of schizophrenia in adult offspring. In particular, schizophrenia patients subjected to prenatal infe... | ['Animals', 'Animals, Newborn', 'Biomimetic Materials', 'Discrimination, Psychological', 'Female', 'Male', 'Photic Stimulation', 'Poly I-C', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Long-Evans', 'Sex Characteristics'] | 21,376,064 | [['B01.050'], ['B01.050.050.282'], ['J01.637.087'], ['F02.463.593.257'], ['E05.723.729'], ['D13.695.578.550.560.600', 'D13.695.578.550.650.600'], ['G08.686.784.769'], ['C13.703.824.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['G08.686.815']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Generation and functional characterization of T cell lines and clones specific for Schistosoma japonicum egg antigen in humans. | T cell lines specific for Schistosoma japonicum egg Ag were established in vitro from patients with chronic schistosomiasis japonica, and investigated their possible immunopathologic roles by testing lymphokines production and in vitro granuloma formation assay. All lines tested had surface phenotypes of CD3+ CD4+ CD8-... | ['Adult', 'Animals', 'Antigens, Helminth', 'Cell Line', 'Chemical Fractionation', 'Clone Cells', 'Epitopes', 'Granuloma', 'Humans', 'Interleukin-2', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Ovum', 'Phenotype', 'Schistosoma japonicum', 'Schistosomiasis japonica', 'T-Lymphocytes'] | 2,459,210 | [['M01.060.116'], ['B01.050'], ['D23.050.223'], ['A11.251.210'], ['E05.196.155'], ['A11.251.353'], ['D23.050.550'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.3... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of antidepressants in rats trained to discriminate the beta-2 adrenergic agonist clenbuterol. | The ability of indirectly acting agonists such as norepinephrine uptake inhibitors, serotonin reuptake inhibitors, and atypical antidepressants to substitute for clenbuterol, a beta-2 adrenergic agonist, was examined in rats trained to discriminate 0.03 mg/kg clenbuterol and saline using a fixed-ratio 10 (FR 10) schedu... | ['Adrenergic beta-Agonists', 'Animals', 'Antidepressive Agents', 'Antidepressive Agents, Tricyclic', 'Clenbuterol', 'Conditioning, Operant', 'Discrimination Learning', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Adrenergic, beta'] | 10,371,662 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['B01.050'], ['D27.505.954.427.700.122'], ['D27.505.954.427.700.122.055'], ['D02.033.100.291.231', 'D02.092.063.291.231'], ['F02.463.425.179.509'], ['F02.463.425.280'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictive Analytics to Support Real-Time Management in Pathology Facilities. | Predictive analytics can provide valuable support to the effective management of pathology facilities. The introduction of new tests and technologies in anatomical pathology will increase the volume of specimens to be processed, as well as the complexity of pathology processes. In order for predictive analytics to addr... | ['Humans', 'Laboratories, Hospital', 'Ontario', 'Pathology, Surgical', 'Time Management'] | 28,269,873 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['Z01.107.567.176.639'], ['H02.403.650.510'], ['F02.784.412.923', 'F02.784.692.816', 'F04.096.628.779.900', 'N04.452.932']] | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Comparison of oral glucose loading and intravenous glucagon injection as stimuli to C-peptide secretion in normal men. | In 10 healthy men, we have compared the respective effects of an intravenous injection of glucagon (1 mg) and an oral glucose load (75 G) in eliciting the release of C-peptide and insulin from the pancreas. Serum C-peptide and insulin concentrations increased respectively to median values of 190% and 500% at 6 minutes ... | ['Adult', 'C-Peptide', 'Glucagon', 'Glucose', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Male'] | 2,952,415 | [['M01.060.116'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.947.875.359.448'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Abdominoplasty: the use of polypropylene mesh to correct myoaponeurotic-layer deformity. | The aponeurotic layer is a very important element to consider during abdominoplasty. For most patients, a simple midline plication is enough to obtain good results. However, for in patients with severe aponeurotic laxity, some other maneuvers must be performed. The purpose of this study was to evaluate the use of polyp... | ['Abdominal Muscles', 'Abdominal Wall', 'Adult', 'Female', 'Humans', 'Middle Aged', 'Patient Satisfaction', 'Polypropylenes', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Surgical Mesh', 'Suture Techniques', 'Time Factors'] | 15,383,881 | [['A02.633.567.050'], ['A01.923.047.050'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['D02.455.326.271.665.590', 'D05.750.716.550', 'D25.720.716.550', 'J01.637.051.72... | ['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Maturation of somesthetic evoked potentials in man]. | Somaesthetic evoked potentials (SEPs) have been recorded on the parietal scalp of 375 normal and awake children to brief electrical stimulation (0.5 msec) applied to the contralateral median nerve at the wrist. Each SEP was obtained by summation of the responses to 150 stimuli delivered at a frequency of 1/sec. The pop... | ['Adolescent', 'Aging', 'Child', 'Child, Preschool', 'Evoked Potentials', 'Humans', 'Infant', 'Infant, Newborn', 'Neural Pathways', 'Reaction Time', 'Somatosensory Cortex', 'Wakefulness'] | 57,038 | [['M01.060.057'], ['G07.345.124'], ['M01.060.406'], ['M01.060.406.448'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A08.612'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['A08.186.211.200.885.287.500.670.675', 'A08.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
DNA immunization with a herpes simplex virus 2 bacterial artificial chromosome. | Construction of a herpes simplex virus 2 (HSV-2) bacterial artificial chromosome (BAC) is described. BAC vector sequences were inserted into the thymidine kinase gene of HSV-2 by homologous recombination. DNA from cells infected with the resulting recombinant virus was transformed into E. coli, and colonies containing ... | ['Animals', 'Antibodies, Viral', 'Chlorocebus aethiops', 'Chromosomes, Artificial, Bacterial', 'Herpes Genitalis', 'Herpesvirus 2, Human', 'Immunization', 'Mice', 'Mice, Inbred BALB C', 'Neutralization Tests', 'Thymidine Kinase', 'Vaccines, DNA', 'Vero Cells', 'Viral Vaccines'] | 14,972,567 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A11.284.187.178.170', 'A11.284.187.190.170', 'A20.812.170', 'G05.360.162.178.170', 'G05.360.162.190.170', 'G05.360.337.249.170'], ['C01.221.812.640.350'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of electroporation on iontophoretic transdermal delivery of calcium regulating hormones. | Electrically-assisted delivery by iontophoresis and/or electroporation was used in vitro to deliver the calcium regulating hormones, salmon calcitonin (sCT) and parathyroid hormone (1-34) (PTH) through human epidermis. Such delivery could be useful for chronic treatment of post-menopausal osteoporosis and other clinica... | ['Administration, Cutaneous', 'Calcitonin', 'Drug Delivery Systems', 'Electroporation', 'Epidermis', 'Female', 'Humans', 'Iontophoresis', 'Osteoporosis, Postmenopausal', 'Parathyroid Hormone', 'Peptide Fragments'] | 10,742,574 | [['E02.319.267.120.060'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['E02.319.300'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['A10.272.497', 'A17.815.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.650', 'E05.301.300.575'], ['C0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Meta-analysis: effect of interactive communication between collaborating primary care physicians and specialists. | BACKGROUND: Whether collaborative care models that enable interactive communication (timely, 2-way exchange of pertinent clinical information directly between primary care and specialist physicians) improve patient outcomes is uncertain.PURPOSE: To assess the effects of interactive communication between collaborating p... | ['Ambulatory Care', 'Cooperative Behavior', 'Diabetes Mellitus', 'Humans', 'Interdisciplinary Communication', 'Medicine', 'Mental Disorders', 'Neoplasms', 'Outcome Assessment, Health Care', 'Physicians, Family', 'Publication Bias', 'Reproducibility of Results'] | 20,157,139 | [['E02.760.106', 'N02.421.585.106'], ['F01.145.813.115'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['H02.403'], ['F03'], ['C04'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['M01.526.485.810.770', 'N02.360.810.77... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Physiotherapists' use of evidence based practice: a cross-national study. | This study investigated clinical physiotherapists' reasons for their use of treatment techniques, with a particular focus on their utilisation of journal review and research literature. A questionnaire was completed by 180 physiotherapists in England and 141 physiotherapists in Australia. Despite the greater prevalence... | ['Attitude of Health Personnel', 'Australia', 'Cross-Cultural Comparison', 'Educational Status', 'England', 'Evidence-Based Medicine', 'Humans', 'Physical Therapy Modalities'] | 9,238,748 | [['F01.100.050', 'N05.300.100'], ['Z01.639.100', 'Z01.678.100.373'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['N01.824.196'], ['Z01.542.363.300'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.779', 'E02.831.535']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Identification of a lytic Pseudomonas aeruginosa phage depolymerase and its anti-biofilm effect and bactericidal contribution to serum. | Pseudomonas aeruginosa (P. aeruginosa) infection has imposed a great threat to patients with cystic fibrosis. With the emergence of multidrug-resistant P. aeruginosa, developing an alternative anti-microbial strategy is indispensable and more urgent than ever. In this study, a lytic P. aeruginosa phage was isolated fro... | ['Biofilms', 'Drug Resistance, Multiple', 'Humans', 'Pseudomonas Infections', 'Pseudomonas Phages', 'Pseudomonas aeruginosa', 'Sewage'] | 30,937,696 | [['A20.593', 'G06.120'], ['G07.690.773.984.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.739'], ['B04.123.660'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['D20.944.932.500']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Malignant pleural and peritoneal mesotheliomas in former miners and millers of crocidolite at Wittenoom, Western Australia. | AIMS: To report the number of malignant pleural and peritoneal mesotheliomas that have occurred in former Wittenoom crocidolite workers to the end of 2000, and to compare this with earlier predictions.METHODS: A group of 6493 men and 415 women who had worked at the former Wittenoom crocidolite mine and mill at some tim... | ['Adult', 'Age of Onset', 'Aged', 'Asbestos, Crocidolite', 'Female', 'Humans', 'Male', 'Mesothelioma', 'Middle Aged', 'Mining', 'Mortality', 'Occupational Diseases', 'Occupational Exposure', 'Peritoneal Neoplasms', 'Pleural Neoplasms', 'Survival Analysis', 'Textile Industry', 'Western Australia'] | 15,031,405 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['D01.578.725.050.050.100', 'D01.837.725.700.760.070.050.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['M01.060.116.630'], ['J01.576.655.875.500'], ['E05.318.308.985.550', 'N... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Adhesive strength and bonding behavior in graphite-marked bracket positioning]. | During a one-year observation period eleven patients treated with fixed appliances and 164 brackets which had been bonded in pairs, were checked at periodic intervals. Every patient had brackets positioned on the teeth in the first and fourth quadrant without graphite marking and in the second and third quadrant with g... | ['Acid Etching, Dental', 'Adhesiveness', 'Adolescent', 'Child', 'Dental Bonding', 'Dental Stress Analysis', 'Follow-Up Studies', 'Graphite', 'Humans', 'In Vitro Techniques', 'Orthodontic Appliances'] | 2,647,598 | [['E06.931.475.111'], ['G02.860.139'], ['M01.060.057'], ['M01.060.406'], ['E06.095'], ['E06.308'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D01.268.150.300', 'D01.578.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E06.658.453']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion. | In order to identify the function of deafness locus putative guanine nucleotide exchange factor (DelGEF), a protein homologous to the nucleotide exchange factor for the small GTPase Ran, a cDNA library was screened for interacting proteins using a yeast two-hybrid system. The human homologue of Sec5, a protein involved... | ['Amino Acid Sequence', 'Carrier Proteins', 'Cations', 'Down-Regulation', 'Exocytosis', 'Guanine Nucleotide Exchange Factors', 'HeLa Cells', 'Humans', 'Membrane Proteins', 'Metals', 'Molecular Sequence Data', 'Nucleotides', 'Oligonucleotides, Antisense', 'Proteoglycans', 'RNA, Messenger', 'Sequence Homology', 'Tissue D... | 12,459,492 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157'], ['D01.248.497.300'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G04.468'], ['D12.644.360.325.300', 'D12.776.476.325.300'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Endometrial change in the annual reproductive cycle of the mare. | Cervical and endometrial swabs were taken from 7 mares at various stages of the oestrous cycle. There was no consistent pattern of cell change throughout the cycle. The dominant cell in smears from normal mares was the columnar epithelial cell, especially in smears obtained during oestrus. A ciliated columnar epithelia... | ['Animals', 'Endometrium', 'Epithelial Cells', 'Estrus', 'Female', 'Horses', 'Periodicity', 'Pregnancy', 'Vaginal Smears'] | 6,962,851 | [['B01.050'], ['A05.360.319.679.490'], ['A11.436'], ['G08.686.195.500'], ['B01.050.150.900.649.313.984.235.472'], ['G01.910.645', 'G07.180.562'], ['G08.686.784.769'], ['E01.370.225.500.384.100.800', 'E01.370.225.998.054.800', 'E01.370.378.900', 'E04.074.800', 'E05.200.500.384.100.800', 'E05.200.998.054.800', 'E05.242.3... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prevalence of physical abuse in childhood and exposure to parental violence in a Brazilian sample]. | The aim of this study was to investigate the prevalence of physical abuse and exposure to parental violence during childhood, in relation to socio-demographic characteristics. Multi-stage sampling was used to select 3,007 individuals 14 years or older in 2005-2006, from all regions of the country. The study detected ca... | ['Adolescent', 'Adult', 'Adult Survivors of Child Abuse', 'Aged', 'Aged, 80 and over', 'Brazil', 'Child', 'Domestic Violence', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Socioeconomic Factors', 'Young Adult'] | 19,936,484 | [['M01.060.057'], ['M01.060.116'], ['M01.135.500', 'M01.860.300.500'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.757.176'], ['M01.060.406'], ['I01.198.240.856.350', 'I01.880.735.900.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.75... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Erdheim-Chester disease: case report with unique postmortem magnetic resonance imaging, high-resolution radiography, and pathologic correlation. | Erdheim-Chester disease is an infiltrative form of histiocytosis characterized by replacement of normal tissues by lipid-laden histiocytes. The disease typically infiltrates the medullary portion of the diaphysis and metaphysis of long bones, producing a characteristic radiological pattern dominated by bone sclerosis. ... | ['Bone and Bones', 'Erdheim-Chester Disease', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Radiography'] | 19,237,062 | [['A02.835.232', 'A10.165.265'], ['C15.604.250.410.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.700']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Translational isomerism in a [3]catenane and a [3]rotaxane. | [structure: see text] Post-assembly covalent modification using Wittig chemistry of [2]rotaxane ylides, wherein NH(2)(+) centers in the dumbbell-shaped components are recognized by dibenzo[24]crown-8 (DB24C8) rings, has afforded a [3]catenane and a [3]rotaxane with a precise and synthetically prescribed shortage of DB2... | ['Anthracenes', 'Isomerism', 'Magnetic Resonance Spectroscopy', 'Polycyclic Compounds', 'Rotaxanes'] | 12,375,887 | [['D02.455.426.559.847.117', 'D04.615.117'], ['G02.111.570.685', 'G02.607.445'], ['E05.196.867.519'], ['D04'], ['D02.825']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Huge calcified aneurysm of the sinus of Valsalva. | Aneurysms of the sinus of Valsalva often remain undiagnosed until they rupture. A 61-year-old man had a huge, heavily calcified unruptured aneurysm, originating from the right sinus of Valsalva, detected incidentally on a chest radiograph taken for the diagnosis of cardiomegaly. Two-dimensional echocardiography reveale... | ['Aortic Aneurysm', 'Calcinosis', 'Cardiomegaly', 'Echocardiography, Doppler, Color', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Regional Blood Flow', 'Sinus of Valsalva'] | 11,266,202 | [['C14.907.055.239', 'C14.907.109.139'], ['C18.452.174.130'], ['C14.280.195', 'C23.300.775.250'], ['E01.370.350.130.750.220.220', 'E01.370.350.850.220.220.220', 'E01.370.350.850.850.220.220', 'E01.370.350.850.850.850.850.220', 'E01.370.370.380.220.220.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.11... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Defining and Measuring Sustainability in the Food & Fitness Initiative. | Several frameworks for defining and measuring sustainability in public health have been documented in the literature. For the Food & Fitness Initiative, sustainability was a central aim at the outset and was defined broadly throughout the project. Sustainability included not only funding and resources necessary to supp... | ['Adult', 'Community Participation', 'Community-Institutional Relations', 'Exercise', 'Female', 'Food', 'Health Promotion', 'Humans', 'Interviews as Topic', 'Leadership', 'Male', 'Middle Aged', 'Policy Making', 'Program Evaluation', 'Surveys and Questionnaires', 'United States'] | 30,176,770 | [['M01.060.116'], ['N02.421.143.212', 'N03.540.245.360'], ['N04.452.822.210'], ['G11.427.410.698.277', 'I03.350'], ['G07.203.300', 'J02.500'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420']... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psycholo... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
[Sex differences in EEG background activity: a study with quantitative analysis in normal adults]. | The present study performed quantitative EEG analysis in normal 20 males and 20 females, aged 18-26 years, in order to examine the sex differences in EEG activity at rest. The females had more absolute EEG power than the males, with significant differences observed for delta, theta and beta bands. In contrast, no signi... | ['Adolescent', 'Adult', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Sex Factors'] | 7,699,933 | [['M01.060.057'], ['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N05.715.350.675', 'N06.850.490.875']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of unilateral versus bilateral pedicle screw fixation at the level of fracture using posterior short-segment pedicle instrumentation in the treatment of severe thoracolumbar burst fractures. | BACKGROUND: Thoracolumbar burst fractures (TBFs) are often followed by bilateral pedicle screw fixation (BPSF) at the level of fracture using posterior short-segment pedicle instrumentation (SSPI). There has been increasing support for unilateral pedicle screw fixation (UPSF) in an attempt to reduce complications and c... | ['Adult', 'Bone Screws', 'Female', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Humans', 'Injury Severity Score', 'Male', 'Middle Aged', 'Pedicle Screws', 'Spinal Fractures', 'Thoracic Vertebrae', 'Treatment Outcome', 'Visual Analog Scale'] | 28,343,026 | [['M01.060.116'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E04.555.300.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.500.800.400'], ['M01.060.116.630'], ['E07.695.370... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional melanocytes derived from human pluripotent stem cells engraft into pluristratified epidermis. | Melanocytes are essential for skin homeostasis and protection, and their defects in humans lead to a wide array of diseases that are potentially extremely severe. To date, the analysis of molecular mechanisms and the function of human melanocytes have been limited because of the difficulties in accessing large numbers ... | ['Adult Stem Cells', 'Bone Morphogenetic Protein 4', 'Cell Differentiation', 'Cell Line', 'Epidermal Cells', 'Epidermis', 'Humans', 'Hypopigmentation', 'Melanocytes', 'Pluripotent Stem Cells', 'Stem Cell Transplantation'] | 21,856,949 | [['A11.872.040'], ['D12.644.276.954.200.400', 'D12.776.467.942.200.400', 'D23.529.942.200.400'], ['G04.152'], ['A11.251.210'], ['A11.409'], ['A10.272.497', 'A17.815.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.621.440'], ['A11.409.750', 'A11.436.613'], ['A11.872.700'], ['E02.095.147.500.500', 'E04.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Yeast ribosomal protein L26 is located at the ribosomal subunit interface as determined by chemical cross-linking. | Previous studies suggested that yeast ribosomal protein L26 was a candidate for the ribosomal subunit interface region. The present study used protein-protein cross-linking to identify neighboring proteins in intact 80S ribosomes of Saccharomyces cerevisiae. To facilitate identification of cross-linked pairs involving ... | ['Cross-Linking Reagents', 'Electrophoresis, Polyacrylamide Gel', 'Fluoresceins', 'Ribosomal Proteins', 'Ribosomes', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Succinimides'] | 9,672,752 | [['D27.720.470.410.210'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['D12.776.835'], ['A11.284.430.214.190.875.811'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['D02.478.770', 'D03.383.773.812.852']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imaging of Chemotherapy-Induced Acute Cardiotoxicity with 18 | Many chemotherapy agents are toxic to the heart, such that increasing numbers of cancer survivors are now living with the potentially lethal cardiovascular consequences of their treatment. Earlier and more sensitive detection of chemotherapy-induced cardiotoxicity may allow improved treatment strategies and increase lo... | ['Animals', 'Antineoplastic Agents', 'Cardiotoxicity', 'Doxorubicin', 'Fluorine Radioisotopes', 'Hydrophobic and Hydrophilic Interactions', 'Isotope Labeling', 'Male', 'Organophosphorus Compounds', 'Positron-Emission Tomography', 'Rats', 'Rats, Sprague-Dawley', 'Tissue Distribution'] | 31,147,403 | [['B01.050'], ['D27.505.954.248'], ['C14.280.260', 'C23.550.161', 'C25.100.389', 'C26.733.266', 'G01.750.748.500.266'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D01.496.749.340'], ['G02.409'], ['E05.522'], ['D02.705'], ['E01.370.350.350.800.700', 'E01.370.350.600.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simplified standardized technique for living donor liver transplantation using left liver graft plus caudate lobe. | Concomitant resection of the caudate lobe (CL) would increase the liver mass in the left liver graft. We tried to define a simplified standardized technique for adult living donor liver transplantation using the extended left lobe (ELL) plus CL (ELLC) through a prospective study of 27 consecutive ELLC graft cases in 20... | ['Adult', 'Female', 'Humans', 'Liver', 'Liver Regeneration', 'Liver Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Patient Selection', 'Prospective Studies'] | 15,497,157 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['G10.261.475', 'G16.762.468'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.898.656'], ['M01.060.116.630'], ['E05.581.500.653', 'N04.590.731'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characteristics of hospitalizations for patients who use a structured clinical care program for children with medical complexity. | OBJECTIVE: To describe the characteristics of hospitalizations for patients who use clinical programs that provide care coordination for children with multiple, chronic medical conditions.STUDY DESIGN: Retrospective analysis of 1083 patients hospitalized between June 2006 and July 2008 who used a structured, pediatric ... | ['Adolescent', 'Child', 'Child Health Services', 'Child, Preschool', 'Chronic Disease', 'Female', 'Health Care Surveys', 'Hospitalization', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Infant, Newborn', 'Inpatients', 'Insurance, Health', 'Male', 'Prevalence', 'Retrospective Studies', 'State Health Plans', 'United State... | 21,429,511 | [['M01.060.057'], ['M01.060.406'], ['N02.421.143.130'], ['M01.060.406.448'], ['C23.550.291.500'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.556.437'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prey selection in the leopard frog: choosing in biased and unbiased situations. | When given the option between a ground-level prey presented in front and another prey presented 90 degrees to the side, leopard frogs have a front preference. When given a choice between prey objects presented at the left and right sides, some individual leopard frogs have a side preference. Repeated prey object presen... | ['Animals', 'Attention', 'Choice Behavior', 'Functional Laterality', 'Orientation', 'Predatory Behavior', 'Rana pipiens', 'Visual Fields'] | 9,667,807 | [['B01.050'], ['F02.830.104.214'], ['F02.463.785.373.346'], ['F02.830.297.425', 'G11.561.225.425'], ['F01.058.577', 'F02.830.606'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['B01.050.150.900.090.180.708.310'], ['F02.463.593.932.934', 'G14.950']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measuring Geographic "Hot Spots" of Racial/Ethnic Disparities: An Application to Mental Health Care. | This article identifies geographic "hot spots" of racial/ethnic disparities in mental health care access. Using data from the 2001-2003 Collaborative Psychiatric Epidemiology Surveys(CPES), we identified metropolitan statistical areas(MSAs) with the largest mental health care access disparities ("hot spots") as well as... | ['California', 'Ethnic Groups', 'European Continental Ancestry Group', 'Georgia', 'Health Services Accessibility', 'Healthcare Disparities', 'Hispanic Americans', 'Humans', 'Mental Health', 'Mental Health Services', 'Texas', 'Virginia'] | 27,180,702 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['M01.686.754', 'N01.224.317'], ['M01.686.508.400'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['N04.590.374.350', 'N05.300.430'], ['N04.590.374.380', 'N05.300.493'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', ... | ['Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
LCM-seq reveals the crucial role of LsSOC1 in heat-promoted bolting of lettuce (Lactuca sativa L.). | Lettuce (Lactuca sativa L.) is one of the most economically important vegetables. The floral transition in lettuce is accelerated under high temperatures, which can significantly decrease yields. However, the molecular mechanism underlying the floral transition in lettuce is poorly known. Using laser capture microdisse... | ['Flowers', 'Gene Expression Profiling', 'Gene Knockdown Techniques', 'Hot Temperature', 'Lettuce', 'MADS Domain Proteins', 'Plant Proteins', 'Transcriptome'] | 29,772,090 | [['A18.024.249.500'], ['E05.393.332'], ['E05.393.335.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.650.940.800.575.912.250.100.500'], ['D12.776.260.400.249', 'D12.776.930.397'], ['D12.776.765'], ['G02.111.873.750', '... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of liquid meals on duodenogastric reflux in humans. | In humans duodenogastric reflux and gastric emptying were measured simultaneously by a two-marker technique that avoids transpyloric intubation. The duodenal marker consisted of 99mTc-labeled Hepatobida and was infused intravenously at a constant rate. Hepatobida was cleared almost exclusively by the liver and entered ... | ['Adult', 'Duodenum', 'Eating', 'Fasting', 'Fat Emulsions, Intravenous', 'Female', 'Gastric Emptying', 'Humans', 'Kinetics', 'Male', 'Mathematics', 'Peptones', 'Stomach', 'Technetium'] | 6,896,405 | [['M01.060.116'], ['A03.556.124.684.124', 'A03.556.875.249'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D26.255.165.260.270', 'D26.776.708.733.500', 'D27.505.954.578.733.500', 'D27.720.752.733.500'], ['G10.261.360.400'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Perceived social support from strength and conditioning coaches among injured student athletes. | Injuries suffered by student athletes not only affect their physical ability to perform in sport but also have psychological effects as well. The purpose of this study was to examine student athletes' perceptions, expectations, and satisfaction of the social support provided by their strength and conditioning coach (SC... | ['Adolescent', 'Athletes', 'Athletic Injuries', 'Female', 'Humans', 'Male', 'Social Support', 'Young Adult'] | 22,446,680 | [['M01.060.057'], ['M01.072'], ['C26.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.853.500.600'], ['M01.060.116.815']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Selective initiation and transmission of disseminated neoplasia in the soft shell clam Mya arenaria dependent on natural disease prevalence and animal size. | Disseminated neoplasia, a diffuse tumor of the hemolymph system, is one of the six most destructive diseases among bivalve mollusk populations, characterized by the development of abnormal, rounded blood cells that actively proliferate. Though the specific etiology of disseminated neoplasia in Mya arenaria remains unde... | ['Animals', 'Bromodeoxyuridine', 'Hemocytes', 'Hemolymph', 'Mya', 'Prevalence'] | 23,079,141 | [['B01.050'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['A11.118.480', 'A15.145.229.480'], ['A13.453'], ['B01.050.500.644.080.535'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cost-Effectiveness Analysis of Systemic Therapies in Advanced Pancreatic Cancer in the Canadian Health Care System. | OBJECTIVES: To assess the cost-effectiveness of gemcitabine (G), G + 5-fluorouracil, G + capecitabine, G + cisplatin, G + oxaliplatin, G + erlotinib, G + nab-paclitaxel (GnP), and FOLFIRINOX in the treatment of advanced pancreatic cancer from a Canadian public health payer's perspective, using data from a recently publ... | ['Antineoplastic Combined Chemotherapy Protocols', 'Bayes Theorem', 'Canada', 'Cost-Benefit Analysis', 'Decision Support Techniques', 'Drug Costs', 'Humans', 'Markov Chains', 'Models, Economic', 'Network Meta-Analysis', 'Pancreatic Neoplasms', 'Quality-Adjusted Life Years', 'Randomized Controlled Trials as Topic', 'Sta... | 28,408,000 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['Z01.107.567.176'], ['N03.219.151.125'], ['E05.245', 'L01.313.500.750.190'], ['N03.219.151.400.350', 'N05.300.375.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. | Deregulated cellular signalling is a common hallmark of disease, and delineating tissue phosphoproteomes is key to unravelling the underlying mechanisms. Here we present the broadest tissue catalogue of phosphoproteins to date, covering 31,480 phosphorylation sites on 7,280 proteins quantified across 14 rat organs and ... | ['Animals', 'Chromatography, Liquid', 'Humans', 'In Vitro Techniques', 'Liver', 'Muscle, Skeletal', 'Phosphoproteins', 'Phosphorylation', 'Phosphotyrosine', 'Protein Binding', 'Rats', 'Rats, Sprague-Dawley', 'Tandem Mass Spectrometry'] | 22,673,903 | [['B01.050'], ['E05.196.181.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A03.620'], ['A02.633.567', 'A10.690.552.500'], ['D12.776.744'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D12.125.072.050.875.750', 'D12.125.740.740'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations between genetic variants and the severity of metabolic syndrome in subjects with type 2 diabetes. | Metabolic syndrome (MetS) includes obesity, dyslipidemia, elevated blood pressure, and dysglycemia. Subjects with type 2 diabetes (T2D) exhibit features of MetS. The etiology of MetS is complex, involving both environmental and genetic factors. In this study, we examined the role of specific candidate genetic variants ... | ['Adult', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Polymorphism, Single Nucleotide'] | 25,867,398 | [['M01.060.116'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['G05.36... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Revisiting vascularized muscle flaps for complicated sternal wounds in children. | Surgeons at our center previously reported a case of a 2-month-old infant who underwent closure of an infected sternal wound following open cardiac surgery with debridement followed by closure with bilateral pectoralis muscle flaps and a unilateral rectus abdominis muscle flap. The success of the procedure has spawned ... | ['Cardiac Surgical Procedures', 'Child', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Male', 'Postoperative Complications', 'Rectus Abdominis', 'Sternum', 'Surgical Flaps', 'Surgical Wound Dehiscence', 'Surgical Wound Infection'] | 16,258,310 | [['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C23.550.767'], ['A02.633.567.050.800'], ['A02.835.232.570.750'], ['A10.850.710', 'E07.862.710'], ['C23.550.767.887'], ['C01.947.692', 'C23.550.767.925'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Histological techniques to improve testing of pulpal response of teeth to filling material. | Two fixation fluids, two fixation techniques and two embedding methods were investigated for their effects on the quality of sections of teeth for pulpal response to filling materials to improve evaluation of pulpal responses. Sections from 32 baboon teeth were prepared, half with experimental cavities and half without... | ['Animals', 'Dental Pulp', 'Fixatives', 'Formaldehyde', 'Glutaral', 'Histocytological Preparation Techniques', 'Incisor', 'Microtomy', 'Molar', 'Papio', 'Root Canal Filling Materials', 'Tissue Embedding', 'Tissue Fixation'] | 8,268,323 | [['B01.050'], ['A14.549.167.900.260'], ['D27.720.355'], ['D02.047.407'], ['D02.047.532'], ['E01.370.225.500.620', 'E01.370.225.750.600', 'E05.200.500.620', 'E05.200.750.600'], ['A14.549.167.860.425'], ['E01.370.225.500.620.530', 'E01.370.225.750.600.530', 'E05.200.500.620.530', 'E05.200.750.600.530'], ['A14.549.167.860... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
An integrated framework for reporting clinically relevant biomarkers from paired tumor/normal genomic and transcriptomic sequencing data in support of clinical trials in personalized medicine. | The ability to rapidly sequence the tumor and germline DNA of an individual holds the eventual promise of revolutionizing our ability to match targeted therapies to tumors harboring the associated genetic biomarkers. Analyzing high throughput genomic data consisting of millions of base pairs and discovering alterations... | ['Biomarkers, Tumor', 'Clinical Trials as Topic', 'Computational Biology', 'Databases, Genetic', 'Gene Expression Profiling', 'Genetic Variation', 'Genomics', 'Humans', 'Molecular Targeted Therapy', 'Neoplasms', 'Precision Medicine'] | 25,592,568 | [['D23.101.140'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E05.393.332'], ['G05.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Case report: Borrelia valaisiana infection in a Japanese man associated with traveling to foreign countries. | A 78-year-old Japanese man who had clinical symptoms and a flu-like illness with fever, chills, diarrhea, and arthralgia had traveled to Cambodia and Khabarovsk, Russia, before the onset of symptoms and illness. He had been bitten by an Ixodes persulcatus tick in which the DNA of Borrelia valaisiana was detected. The p... | ['Aged', 'Animals', 'Anti-Bacterial Agents', 'Borrelia', 'Borrelia Infections', 'Flagellin', 'Humans', 'Immunoglobulin M', 'Ixodes', 'Japan', 'Male', 'Minocycline', 'RNA, Ribosomal, 16S', 'Sequence Homology, Nucleic Acid', 'Travel', 'Treatment Outcome'] | 18,165,534 | [['M01.060.116.100'], ['B01.050'], ['D27.505.954.122.085'], ['B03.440.425.410.711.193', 'B03.851.595.193'], ['C01.150.252.400.794.352'], ['D12.776.097.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['B01.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Antiplasmodial activity of root extract and fractions of Croton zambesicus. | AIM OF THE STUDY: Antiplasmodial activity of root extract and fractions of Croton zambesicus were evaluated to ascertain the folkloric claim of its antimalarial activity and elucidate its antiplasmodial mechanism of action.MATERIAL AND METHOD: The crude ethanolic root extract (27-81 mg/kg) and gradient fractions (n- he... | ['Animals', 'Antimalarials', 'Chloroquine', 'Croton', 'Female', 'Lethal Dose 50', 'Malaria', 'Male', 'Mice', 'Parasitemia', 'Phytotherapy', 'Plant Extracts', 'Plant Roots', 'Plasmodium berghei', 'Pyrimethamine'] | 18,996,464 | [['B01.050'], ['D27.505.954.122.250.100.085'], ['D03.633.100.810.050.180'], ['B01.650.940.800.575.912.250.859.797.438.199'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['C01.610.752.530', 'C01.920.875'], ['B01.050.150.900.649.313.992.635.505.500'], ['C01.610.695', 'C23.550.470.790.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of retinoid receptors in non-neoplastic canine lymph nodes and in lymphoma. | This study evaluated the difference in retinoid receptor expression between non-neoplastic lymph nodes and nodal lymphoma in dogs. Retinoid receptor expression was evaluated by immunohistochemistry in 32 canine lymph nodes. The lymph nodes had been previously diagnosed as non-neoplastic (6 normal and 7 hyperplastic lym... | ['Animals', 'Dog Diseases', 'Dogs', 'Gene Expression Regulation, Neoplastic', 'Lymph Nodes', 'Lymphoma, B-Cell', 'Lymphoma, T-Cell', 'Retinoid X Receptors'] | 24,381,339 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['G05.308.370'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.557.386.480.150', 'C15.604.515.569.480.150', 'C20.683.515.761.480.150'], ['C04.557.386.480.750', 'C15.604.515.569.480.750', 'C20.683.515.761.480.750'], ['D12.776.826.701.500', 'D12.776.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A urine preservative system to maintain bacterial counts. A laboratory and clinical evaluation. | The urinary tract is a common site of infection in the hospitalized, institutionalized, or ambulatory patient population. Ideally, urine should be cultured immediately or refrigerated up to 24 hours for quantitative examination for microorganisms. In the evaluation of patients at their homes or in long-term care facili... | ['Bacteria', 'Boric Acids', 'Cost-Benefit Analysis', 'Evaluation Studies as Topic', 'False Negative Reactions', 'False Positive Reactions', 'Humans', 'Microbial Sensitivity Tests', 'Preservation, Biological', 'Refrigeration', 'Specimen Handling', 'Urine'] | 3,924,460 | [['B03'], ['D01.029.260.093', 'D01.132.250', 'D02.203.130'], ['N03.219.151.125'], ['E05.337', 'N05.715.360.335'], ['E01.354.340'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E02.792', 'E05.760'], ['E02.792.643', 'E05.760.643'], ['E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
(S)-UH-301 antagonizes (R)-8-OH-DPAT-induced cardiovascular effects in the rat. | The 5-HT1A-receptor antagonist (S)-UH-301 (S)-5-fluoro-8-hydroxy-2- (dipropylamino)tetralin) completely antagonized the hypotension and bradycardia induced by (R) = 8-OH DPAT [R)-8-hydroxy-2- (dipropylamino)tetralin) in conscious rats. (S)-UH-301 alone induced a weak hypertension, which might be due to its 5-HT1A-recep... | ['8-Hydroxy-2-(di-n-propylamino)tetralin', 'Animals', 'Cardiovascular System', 'Consciousness', 'Male', 'Rats', 'Rats, Inbred Strains', 'Serotonin Antagonists', 'Sodium Chloride', 'Stereoisomerism', 'Tetrahydronaphthalenes'] | 1,833,212 | [['D02.455.426.559.847.638.960.400', 'D04.615.638.960.400'], ['B01.050'], ['A07'], ['F02.463.188.409', 'F02.830.233'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D27.505.519.625.850.850', 'D27.505.696.577.850.850'], ['D01.210.450.150.875', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peripheral arterial circulation in individuals with impaired glucose tolerance. | Employees of a telephone company in Naples (N = 1376) were screened by oral glucose tolerance test (OGTT, 75 g). All those with impaired glucose tolerance (IGT) (N = 69) plus 138 normoglycemic controls, matched by sex, age, and body mass index (BMI, kg/m2), were selected to participate in this study. All participants w... | ['Adult', 'Arteriosclerosis', 'Blood Circulation', 'Blood Pressure', 'Female', 'Glucose Tolerance Test', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Plethysmography', 'Risk'] | 4,075,946 | [['M01.060.116'], ['C14.907.137.126'], ['G09.330.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['E01.370.370.610'], ['E05.318.740.600.800', 'G17.680.750'... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunogenicity and protective efficacy of Escherichia coli expressed Plasmodium falciparum merozoite surface protein-1(42) using human compatible adjuvants. | The C-terminal 42-kDa fragment of the merozoite surface protein-1 of Plasmodium falciparum (PfMSP-1(42)) was expressed as a recombinant protein in Escherichia coli and purified to near homogeneity. We tested the immunogenicity of recombinant PfMSP-1(42) in three clinically acceptable adjuvants (Montanide ISA 720, alum ... | ['Adjuvants, Immunologic', 'Animals', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Enzyme-Linked Immunosorbent Assay', 'Escherichia coli', 'Humans', 'Immunoglobulin G', 'Malaria Vaccines', 'Malaria, Falciparum', 'Merozoite Surface Protein 1', 'Mice', 'Mice, Inbred BALB C', 'Plasmodium falciparum', 'Recombinant Prot... | 16,377,036 | [['D27.505.696.477.067'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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