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Structural stigma and sexual orientation-related reproductive health disparities in a longitudinal cohort study of female adolescents. | INTRODUCTION: Sexual minority female adolescents have worse reproductive health than heterosexual peers; research into the origins of these disparities is limited. Our objective was to examine whether exposure to structural stigma (e.g., societal-level conditions, cultural norms, institutional policies/practices that c... | ['Adolescent', 'Child', 'Female', 'Health Status Disparities', 'Humans', 'Longitudinal Studies', 'Pregnancy', 'Reproductive Health', 'Risk Factors', 'Sexual Behavior', 'Sexual and Gender Minorities', 'Social Stigma'] | 31,238,178 | [['M01.060.057'], ['M01.060.406'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['G08.686.784.769'], ['N01.400.625'], ['E05.318.740.600.800.725', 'N05.715.350... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Organizing activity of Fgf8 on the anterior telencephalon. | The anterior part of the embryonic telencephalon gives rise to several brain regions that are important for animal behavior, including the frontal cortex (FC) and the olfactory bulb. The FC plays an important role in decision-making behaviors, such as social and cognitive behavior, and the olfactory bulb is involved in... | ['Animals', 'Cerebral Cortex', 'Fibroblast Growth Factor 8', 'Fibroblast Growth Factors', 'Gene Expression Regulation, Developmental', 'Mice', 'Olfactory Bulb', 'Telencephalon'] | 29,124,740 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['D12.644.276.624.180', 'D12.776.467.624.180', 'D23.529.624.180'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['G05.308.310'], ['B01.050.150.900.649.313.992.635.505.500'], ['A08.186.211.200.885.388'], ['A08.186.211.200.885']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of high-dose etodolac on renal function. | Previous studies from our laboratory have demonstrated transient effects on renal function by etodolac, 200 mg b.i.d. The current study assessed the effects of a larger dose of etodolac (500 mg b.i.d.) to explore the time course of its renal effects and to determine whether the transient effect would become more prolon... | ['6-Ketoprostaglandin F1 alpha', 'Acetates', 'Adult', 'Aged', 'Aldosterone', 'Anti-Inflammatory Agents, Non-Steroidal', 'Body Weight', 'Dinoprostone', 'Etodolac', 'Humans', 'Kidney', 'Middle Aged', 'Potassium', 'Prostaglandins E', 'Reference Values', 'Renin', 'Sodium'] | 2,957,139 | [['D10.251.355.255.550.400.350', 'D10.251.355.325.450', 'D23.469.050.175.725.400.350'], ['D02.241.081.018', 'D10.251.400.045'], ['M01.060.116'], ['M01.060.116.100'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C23.888.1... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nutritional and chemical composition and antiviral activity of cultivated seaweed Sargassum naozhouense Tseng et Lu. | Sargassum naozhouense is a brown seaweed used in folk medicine and applied for thousands of years in Zhanjiang, Guangdong province, China. This study is the first time to investigate its chemical composition and antiviral activity. On the dry weight basis, this seaweed was constituted of ca. 35.18% ash, 11.20% protein,... | ['Amino Acids', 'Animals', 'Antiviral Agents', 'China', 'Chlorocebus aethiops', 'Fatty Acids', 'Minerals', 'Plant Extracts', 'Polysaccharides', 'Sargassum', 'Seaweed', 'Vero Cells'] | 23,271,422 | [['D12.125'], ['B01.050'], ['D27.505.954.122.388'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D10.251'], ['D01.578'], ['D20.215.784.500', 'D26.667'], ['D09.698'], ['B01.750.600.725'], ['B05.080.750'], ['A11.251.210.955', 'A11.436.955']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Marine-terminating glaciers sustain high productivity in Greenland fjords. | Accelerated mass loss from the Greenland ice sheet leads to glacier retreat and an increasing input of glacial meltwater to the fjords and coastal waters around Greenland. These high latitude ecosystems are highly productive and sustain important fisheries, yet it remains uncertain how they will respond to future chang... | ['Animals', 'Arctic Regions', 'Ecosystem', 'Environmental Monitoring', 'Estuaries', 'Fresh Water', 'Greenland', 'Ice Cover', 'Phytoplankton', 'Seawater'] | 28,776,870 | [['B01.050'], ['Z01.208'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.625.540'], ['G16.500.275.280', 'N06.230.232'], ['Z01.107.567.403', 'Z01.542.816.124.500', 'Z01.639.400'], ['G01.311.400', 'G16.500.275.410.500', 'N06.230.291.500'], ['B05.080.500.600'], ['G16.500.275.725... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Adequacy of oxygenation in a group of Danish patients with COPD on long-term oxygen therapy. | The aim of this study was to assess the adequacy of oxygenation in patients with chronic obstructive pulmonary disease (COPD) on long-term oxygen therapy (LTOT) in Copenhagen county. Twenty-six patients were enrolled and assessed prospectively by 24-h pulse oximetry. Patients comprised seven males and 19 females with a... | ['Aged', 'Female', 'Humans', 'Lung Diseases, Obstructive', 'Male', 'Oximetry', 'Oxygen Inhalation Therapy', 'Prospective Studies', 'Time Factors'] | 11,057,078 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.124.100.100.600'], ['E02.880.690'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['G01.910.857'... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Preparation and characterization of monoclonal antibody against human LSECtin]. | AIM: To prepare and characterize monoclonal antibody (mAb) against human LSECtin (liver and lymph node sinusoidal endothelial cell C-type lectin) protein.METHODS: BALB/c mice were immunized with prokaryotically expressed human LSECtin protein. The splenocytes from the immunized mice were fused with murine myeloma cells... | ['Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Electrophoresis, Polyacrylamide Gel', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Hybridomas', 'Immunoglobulin Isotypes', 'Lectins, C-Type', 'Mice', 'Mice, Inbred BALB C'] | 16,806,021 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.500.607.512.24... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Fractures of the proximal radius in the growth stage]. | From 1970 to 1985 in the Orthopedic University Clinic (Oskar-Helene-Heim Berlin) 116 children with fractures of the proximal end of the radius received medical treatment. The frequency of the remaining complications like restriction of movement, differences in elbow axis angle (carrying angle), disturbances of growth o... | ['Adolescent', 'Child', 'Elbow Joint', 'Epiphyses, Slipped', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Humans', 'Joint Dislocations', 'Postoperative Complications', 'Radius Fractures', 'Range of Motion, Articular', 'Salter-Harris Fractures', 'Wound Healing'] | 2,042,256 | [['M01.060.057'], ['M01.060.406'], ['A02.835.583.290'], ['C05.116.425'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['C23.550.767'], ['C26.088.268.556', 'C26.404.562'], ['E01... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds. | Expression of urokinase-type plasminogen activator receptor mRNA was examined in vivo in mouse skin wounds by in situ hybridization. Urokinase-type plasminogen activator receptor mRNA was found in keratinocytes at the front of the regenerative epithelial outgrowths at the edge of 12-, 48-, and 96-hour-old wounds. The s... | ['Animals', 'Cell Line', 'Epithelium', 'Female', 'In Situ Hybridization', 'Keratinocytes', 'Mice', 'Mice, Inbred BALB C', 'RNA, Messenger', 'Receptors, Cell Surface', 'Receptors, Urokinase Plasminogen Activator', 'Skin', 'Wound Healing', 'Wounds and Injuries'] | 8,151,132 | [['B01.050'], ['A11.251.210'], ['A10.272'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['A11.409.500', 'A11.436.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of anti-Toxoplasma activity of SDZ 215-918, a cyclosporin derivative lacking immunosuppressive and peptidyl-prolyl-isomerase-inhibiting activity: possible role of a P glycoprotein in Toxoplasma physiology. | The immunosuppressive agent cyclosporin A (CsA) also possesses broad-spectrum antimicrobial activity. Previous investigators have reported that the obligate intracellular protozoan Toxoplasma gondii is sensitive to CsA. We have measured the sensitivity of Toxoplasma to 26 CsA derivatives that maintain only a subset of ... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Animals', 'Calcium Channel Blockers', 'Chlorocebus aethiops', 'Coccidiostats', 'Cyclosporine', 'Cyclosporins', 'Enzyme Inhibitors', 'Female', 'Immunosuppressive Agents', 'Mice', 'Peptidylprolyl Isomerase', 'Rhodamine 123', 'Rhodamines', 'Sensitivity and Speci... | 9,303,374 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['B01.050'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protective effects of tumor necrosis factor-á blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis. | We aimed to investigate the effects of an anti-tumor necrosis factor-á antibody (ATNF) on cartilage and subchondral bone in a rat model of osteoarthritis. Twenty-four rats were randomly divided into three groups: sham-operated group (n=8); anterior cruciate ligament transection (ACLT)+normal saline (NS) group (n=8); an... | ['Adalimumab', 'Animals', 'Anterior Cruciate Ligament', 'Antirheumatic Agents', 'Arthritis, Experimental', 'Arthroplasty, Subchondral', 'Bone and Bones', 'Cartilage, Articular', 'Extracellular Matrix', 'Female', 'Hindlimb', 'Immunohistochemistry', 'Injury Severity Score', 'Matrix Metalloproteinase 13', 'Osteoarthritis'... | 26,445,328 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['B01.050'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['D27.505.954.329'], ['C05.550.114.015', 'E05.598.500.249'], ['E04.555.110.115', 'E04.680.101.115'], ['A02.835.232', 'A1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Functional organization of parietal neuronal responses to optic-flow stimuli. | We analyzed the dissimilarity matrix of neuronal responses to moving visual stimuli using tree clustering and multidimensional scaling (MDS). Single-cell activity was recorded in area 7a while random dots moving coherently in eight different kinds of motion (right-, left-, up-, and downward, clockwise, counterclockwise... | ['Action Potentials', 'Animals', 'Electrophysiology', 'Macaca mulatta', 'Male', 'Motion Perception', 'Neurons', 'Parietal Lobe', 'Visual Perception'] | 12,904,489 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['F02.463.593.932.567'], ['A08.675', 'A11.671'], ['A08.186.211.200.885.287.500.670'], ['F02.463.593.932']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Highly sensitive detection of small ruminant bovine spongiform encephalopathy within transmissible spongiform encephalopathy mixes by serial protein misfolding cyclic amplification. | It is assumed that sheep and goats consumed the same bovine spongiform encephalopathy (BSE)-contaminated meat and bone meal that was fed to cattle and precipitated the BSE epidemic in the United Kingdom that peaked more than 20 years ago. Despite intensive surveillance for cases of BSE within the small ruminant populat... | ['Animals', 'Cattle', 'Clinical Laboratory Techniques', 'Encephalopathy, Bovine Spongiform', 'Goat Diseases', 'Goats', 'Prions', 'Sensitivity and Specificity', 'Sheep', 'Sheep Diseases', 'United Kingdom', 'Veterinary Medicine'] | 25,143,565 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225', 'E05.200'], ['C01.207.800.260', 'C10.228.228.800.260', 'C10.574.843.300', 'C22.196.250'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['D12.776.785'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.75... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Fruit Volatiles of Creeping Cucumber (Solena amplexicaulis) Attract a Generalist Insect Herbivore. | Herbivorous insects employ host plant volatile blends as cue for host recognition. Adults of Aulacophora foveicollis Lucas (Coleoptera: Chrysomelidae) feed on leaves, flowers, and fruits of Solena amplexicaulis (Lam.) Gandhi (syn: Melothria heterophylla) (Cucurbitaceae), commonly known as creeping cucumber. Currently, ... | ['Animals', 'Chemotaxis', 'Coleoptera', 'Cucurbitaceae', 'Female', 'Food Chain', 'Fruit', 'Herbivory', 'Male', 'Volatile Organic Compounds'] | 31,989,491 | [['B01.050'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['B01.050.500.131.617.720.500.500.375'], ['B01.650.940.800.575.912.250.300'], ['G16.500.275.157.250', 'N06.230.124.250'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['F01.145.113.54... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Quantum-mechanical study on the mechanism of peptide bond formation in the ribosome. | Ribosomes transform the genetic information encoded within genes into proteins. In recent years, there has been much progress in the study of this complex molecular machine, but the mechanism of peptide bond formation and the origin of the catalytic power of this ancient enzymatic system are still an unsolved puzzle. A... | ['Models, Molecular', 'Peptides', 'Protein Conformation', 'Quantum Theory', 'Ribosomes', 'Thermodynamics'] | 22,376,156 | [['E05.599.595'], ['D12.644'], ['G02.111.570.820.709'], ['H01.671.579.800'], ['A11.284.430.214.190.875.811'], ['G01.906']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Enthalpic interactions in size exclusion chromatography of pullulan and cellulose in LiCL-N,N-dimethylacetamide. | Enthalpic phenomena were shown to contribute to the size exclusion separation mechanisms during chromatographic analysis of solutions of pullulan and cellulose in LiCl-N,N-dimethylacetamide (LiCl-DMAc) solvent and eluent. The effect of LiCl concentration in the sample solutions and the effect of temperature were of the... | ['Acetamides', 'Cellulose', 'Chromatography, Gel', 'Glucans', 'Lithium Chloride', 'Thermodynamics'] | 12,198,855 | [['D02.065.064', 'D02.241.081.018.110'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E05.196.181.400.250'], ['D05.750.078.562', 'D09.698.365'], ['D01.210.450.150.450', 'D01.510.500'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Diabetes nurse case management: Improving glucose control: 10 years of quality improvement follow-up data. | UNLABELLED: The purpose of this retrospective case-control review is to determine the effectiveness of a registered nurse case managers (RNCMs) certified diabetes educator (CDE) quality improvement case management program. RNCMs have a long tradition of providing chronic care intervention, particularly for the high-ris... | ['Blood Glucose', 'Case Management', 'Diabetes Mellitus', 'Glycated Hemoglobin A', 'Humans', 'Quality Improvement', 'Veterans'] | 26,856,514 | [['D09.947.875.359.448.500'], ['N04.590.233.624.250'], ['C18.452.394.750', 'C19.246'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.293.754', 'N04.761.744'], ['M01.930']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
New York-Tidewater Chapters' History of Military Medicine Award. The military odyssey of Norman Bethune. | While visiting the Peoples Republic of China in 1982, I became aware of the work of the Canadian, Norman Bethune, as a military surgeon. Bethune first served as a stretcher-bearer in an ambulance unit and later as a medical officer with the Allies during the First World War. He also participated in the Spanish Civil Wa... | ['Blood Transfusion', 'Canada', 'China', 'History, 20th Century', 'Humans', 'Military Medicine', 'Mobile Health Units', 'Spain', 'Thoracic Surgery'] | 10,226,448 | [['E02.095.135'], ['Z01.107.567.176'], ['Z01.252.474.164'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.500'], ['N02.278.421.702', 'N02.421.726.233.628'], ['Z01.542.846'], ['H02.403.810.803']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Inhibition of the solid state transformation of carbamazepine in aqueous solution: impact of polymeric properties. | The effects of polymers on the anhydrate-to-hydrate transformation of carbamazepine (CBZ) was investigated. The three types of polymers studied were polyvinylpyrrolidone (PVP), polyvinyl alcohol (PVA) and substituted celluloses which included hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC). Anhydrous CBZ ... | ['Carbamazepine', 'Pharmaceutical Solutions', 'Polymers', 'Water'] | 29,047,297 | [['D03.633.300.240.127'], ['D26.776.708', 'D27.505.954.578', 'D27.720.752'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
PDCD5 functions as a regulator of p53 dynamics in the DNA damage response. | The tumor suppressor p53 plays a central role in cell fate decisions after DNA damage. Programmed Cell Death 5 (PDCD5) interacts with the p53 pathway to promote cell apoptosis. Recombinant human PDCD5 can significantly sensitize different cancers to chemotherapies. In the present paper, we construct a computational mod... | ['Algorithms', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Cell Line, Tumor', 'Computer Simulation', 'DNA Damage', 'DNA Repair', 'Humans', 'Models, Biological', 'Neoplasm Proteins', 'Protein Binding', 'Signal Transduction', 'Tumor Suppressor Protein p53'] | 26,433,055 | [['G17.035', 'L01.224.050'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['A11.251.210.190', 'A11.251.860.180'], ['L01.224.160'], ['G05.200'], ['G02.111.222', 'G05.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['D12.776.624'], ['G02.111.679', 'G03.808'], ['G02.111.820', 'G04.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
NYC condom use and satisfaction and demand for alternative condom products in New York City sexually transmitted disease clinics. | In 2007, via a high-profile media campaign, the New York City Department of Health and Mental Hygiene (NYC DOHMH) introduced the "NYC Condom," the first specially packaged condom unique to a municipality. We conducted a survey to measure NYC Condom awareness of and experience with NYC Condoms and demand for alternative... | ['Adolescent', 'Adult', 'Condoms', 'Confidence Intervals', 'Consumer Behavior', 'Female', 'Health Behavior', 'Health Promotion', 'Health Status', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'New York City', 'Odds Ratio', 'Risk Assessment', 'Risk-Taking', 'Sexually Transmitted Diseases', ... | 21,792,691 | [['M01.060.057'], ['M01.060.116'], ['E07.190.270.150'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['F01.145.236'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Perinatal Outcomes of Fetuses with Early Growth Restriction, Late Growth Restriction, Small for Gestational Age, and Adequate for Gestational Age. | OBJECTIVE: To evaluate the association between early-onset fetal growth restriction (FGR), late-onset FGR, small for gestational age (SGA) and adequate for gestational age (AGA) fetuses and adverse perinatal outcomes.METHODS: This was a retrospective longitudinal study in which 4 groups were evaluated: 1 - early-onse... | ['Critical Care', 'Female', 'Fetal Growth Retardation', 'Gestational Age', 'Humans', 'Infant, Small for Gestational Age', 'Longitudinal Studies', 'Pregnancy', 'Prognosis', 'Respiratory Distress Syndrome, Newborn', 'Retrospective Studies', 'Risk Factors', 'Time Factors', 'Ultrasonography, Prenatal'] | 31,856,287 | [['E02.760.190', 'N02.421.585.190'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460.560'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['G08.686.784.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical characteristics of congenital cervical atresia and associated endometriosis among 96 patients. | OBJECTIVE: To describe the anatomic variety of congenital cervical atresia and to explore the relationship between this disorder and pelvic endometriosis.METHODS: In a retrospective study, records were reviewed for 96 patients with a confirmed diagnosis of congenital cervical atresia treated at a center in Beijing, Chi... | ['Abnormalities, Multiple', 'Adolescent', 'Cervix Uteri', 'Child', 'China', 'Endometriosis', 'Female', 'Humans', 'Pelvic Pain', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Young Adult'] | 27,259,641 | [['C16.131.077'], ['M01.060.057'], ['A05.360.319.679.256'], ['M01.060.406'], ['Z01.252.474.164'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.944'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.5... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Modeling the covariance structure in pharmacokinetic crossover trials. | Pharmacokinetic studies of drug and metabolite concentrations in the blood are usually conducted as crossover trials, especially in phases I and II. A longitudinal series of measurements is collected on each subject within each period. However, much of the dependence among such observations, within and between periods,... | ['Body Fluid Compartments', 'Clinical Trials, Phase I as Topic', 'Clinical Trials, Phase II as Topic', 'Cross-Over Studies', 'Dose-Response Relationship, Drug', 'Humans', 'Models, Biological', 'Models, Statistical', 'Multivariate Analysis', 'Quinolines', 'Regression Analysis', 'Vasodilator Agents'] | 10,473,030 | [['A10.082', 'A12.207.180'], ['E05.318.372.250.250.200', 'N05.715.360.330.250.250.200', 'N06.850.520.450.250.250.200'], ['E05.318.372.250.250.210', 'N05.715.360.330.250.250.210', 'N06.850.520.450.250.250.210'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.690.773.875', 'G07.690.936.500'], ['... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of non-REM sleep on the response of respiratory output to varying inspiratory flow. | It has been shown in mechanically ventilated awake normal humans that increasing inspiratory flow rate (VI) exerts an excitatory effect on respiratory output. It is not known if this effect persists during sleep. To test this, seven normal adults were studied during wakefulness and non-rapid eye movement (non-REM) slee... | ['Adaptation, Physiological', 'Adult', 'Analysis of Variance', 'Female', 'Humans', 'Inhalation', 'Inspiratory Capacity', 'Male', 'Masks', 'Polysomnography', 'Pressure', 'Pulmonary Ventilation', 'Reflex', 'Respiration', 'Respiration, Artificial', 'Respiratory Mechanics', 'Sleep', 'Sleep Stages', 'Ventilators, Mechanical... | 8,630,612 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.772.705.700.390'], ['E01.370.386.700.485.750.900.350', 'G09.772.850.970.500'], ['E07.325.877.500', 'E07.700.500', 'E07.858.594.750', 'J01.637.708.560.78... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
A new series of antiallergic agents. II. Synthesis and activity of new 6,11-dihydrodibenz[b,e]oxepin-carboxylic acid derivatives. | New methods for the preparation of multi-functionalized-6,11-dihydrodibenz[b,e]oxepins were developed. The structural requirements of KW-4994 (1), a promising orally active antiallergic agent, were defined. A carboxyl group at C-2 was critical for enhanced antiallergic activity of 1. The introduction of bromine atom at... | ['Animals', 'Benzoxepins', 'Corpus Striatum', 'Guinea Pigs', 'Histamine H1 Antagonists', 'Hypersensitivity, Delayed', 'Male', 'Rats', 'Rats, Inbred Strains', 'Receptors, Cholinergic', 'Structure-Activity Relationship'] | 1,687,211 | [['B01.050'], ['D03.633.100.245'], ['A08.186.211.200.885.287.249.487'], ['B01.050.150.900.649.313.992.550'], ['D27.505.519.625.375.425.400', 'D27.505.696.577.375.425.400'], ['C20.543.418'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D12.776... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prenatal development and postnatal morbidity of newborn infants of HIV positive mothers]. | Does the maternal HIV-infection itself influence fetal development and neonatal morbidity or are adverse effects related to maternal opiate and nicotine abuse? 17 neonates of HIV-positive women (7 drug users) and 37 controls (17 healthy and 21 opiate exposed newborns) were examined prospectively. A discriminant analysi... | ['Birth Weight', 'Female', 'Fetal Growth Retardation', 'Gestational Age', 'HIV Seropositivity', 'Humans', 'Infant, Newborn', 'Leukocyte Count', 'Methadone', 'Neonatal Abstinence Syndrome', 'Opioid-Related Disorders', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Prospective Studies', 'Risk Factors', 'Smoking', '... | 2,087,239 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['G07.345.500.325.235.968', 'G08.686.320'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chondroma of the tongue. Report of two cases. | Lingual chondromas are very rare tumors. It can be assumed that chondromas of the tongue develop from heterotopic embryonal cartilage. Chondromas are usually seen on the lateral borders of the tongue. Because chondrosarcomas can appear in this location, wide excision of the lesions should be performed. The CO2 laser fa... | ['Adult', 'Child, Preschool', 'Chondroma', 'Humans', 'Male', 'Tongue Neoplasms'] | 6,732,113 | [['M01.060.116'], ['M01.060.406.448'], ['C04.557.450.565.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.591.925', 'C07.465.530.925', 'C07.465.910.470']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of fluvoxamine augmentation and smoking on clozapine serum concentrations. | BACKGROUND: Clozapine (CLZ) is metabolized via cytochrome P450 CYP1A2 to N-desmethylclozapine (NCLZ). Smoking induces CYP1A2 thereby increasing clozapine metabolism whereas fluvoxamine inhibits CYP1A2. Studies suggest that the beneficial effect of fluvoxamine augmentation in raising serum clozapine concentrations also ... | ['Adult', 'Aged', 'Antipsychotic Agents', 'Cigarette Smoking', 'Clozapine', 'Comorbidity', 'Cytochrome P-450 CYP1A2 Inhibitors', 'Drug Synergism', 'Drug Therapy, Combination', 'Female', 'Fluvoxamine', 'Humans', 'Male', 'Middle Aged', 'Schizophrenia', 'Young Adult'] | 31,182,321 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F01.145.805.375.750', 'F01.145.958.875.750'], ['D03.633.300.240.220'], ['N05.715.350.225', 'N06.850.490.687'], ['D27.505.389.500.120', 'D27.505.519.389.335.120'], ['G07.690.773.968.477'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors. | BACKGROUND: Recent clinical trials have demonstrated that HIV protease inhibitors are useful in the treatment of AIDS. It is necessary, however, to use HIV protease inhibitors in combination with other antiviral agents to inhibit the development of resistance. The daunting ability of the virus to rapidly generate resis... | ['Animals', 'Anti-HIV Agents', 'Crystallography, X-Ray', 'Dogs', 'Drug Design', 'HIV', 'HIV Protease Inhibitors', 'Molecular Structure', 'Mutation', 'Protein Binding', 'Urea', 'Virus Replication'] | 9,818,151 | [['B01.050'], ['D27.505.954.122.388.077.088'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B04.820.650.589.650.350'], ['D27.505.519.389.745.900.500', 'D27.505.954.122.388.077.088.420'], ['G02.111.570', 'G02.466'], ['G05.365.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Binocular adaptation to near addition lenses in emmetropic adults. | Near addition lenses are prescribed to pre-presbyopic individuals for treatment of binocular motor problems such as convergence excess and to control the progression of myopia. To date, no investigation has looked at the complete sequence of binocular motor responses during a period of near work with +2D lenses. This i... | ['Accommodation, Ocular', 'Adaptation, Physiological', 'Adult', 'Convergence, Ocular', 'Exotropia', 'Eyeglasses', 'Fixation, Ocular', 'Humans', 'Strabismus', 'Vision, Binocular'] | 18,395,768 | [['G14.010'], ['G07.025', 'G16.012.500'], ['M01.060.116'], ['G14.350.217'], ['C10.292.562.887.650', 'C11.590.810.440'], ['E07.632.500.300'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.562.887', 'C11.590.810'], ['F02.463.593.932.885']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection. | BACKGROUND: Natural killer (NK) cells localize in the microcirculation in antibody-mediated rejection (AMR) and have been postulated to be activated by donor-specific anti-HLA antibodies triggering their CD16a Fc receptors. However, direct evidence for NK cell CD16a triggering in AMR is lacking. We hypothesized that CD... | ['Adaptive Immunity', 'Antigens, CD', 'Biopsy', 'Cells, Cultured', 'Chemokines, C', 'GPI-Linked Proteins', 'Gene Expression Profiling', 'Graft Rejection', 'Humans', 'Kidney Transplantation', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Oligonucleotide Array Sequence Analysis', 'RNA, Messenger', 'Receptors, IgG', ... | 27,906,829 | [['G12.450.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A11.251'], ['D12.644.276.374.200.100', 'D12.776.467.374.200.100', 'D23.125.300.100', 'D23.469.200.100', 'D23.529.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global "omics" evaluation of human placental responses to preeclamptic conditions. | BACKGROUND: Preeclampsia (PE) is a leading cause of maternal death. Its cause is still debated but there is general agreement that the placenta plays a central role. Perhaps the most commonly proposed contributors to PE include placental hypoxia, oxidative stress, and increased proinflammatory cytokines. How the placen... | ['Female', 'Humans', 'Hypoxia', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Oxidative Stress', 'Placenta', 'Pre-Eclampsia', 'Pregnancy', 'Proteomics', 'Tumor Necrosis Factor-alpha'] | 26,970,495 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['G03.673', 'G07.775.750'], ['A16.710'], ['C13.703.395.249'], ['G08.686.784.769'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['D12.644.276.37... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization. | A series of benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives were prepared and evaluated to determine the necessary requirements for high affinity on the 5-HT(4) receptors and high selectivity versus other receptors. The compounds were synthesized by substituting the chlorine atom of benzonaphthyridin... | ['Animals', 'Behavior, Animal', 'COS Cells', 'Chlorocebus aethiops', 'Cyclic AMP', 'Guinea Pigs', 'Lethal Dose 50', 'Male', 'Maze Learning', 'Mice', 'Naphthyridines', 'Quinolines', 'Radioligand Assay', 'Receptors, Serotonin', 'Receptors, Serotonin, 5-HT4', 'Serotonin Antagonists', 'Serotonin Receptor Agonists', 'Struct... | 12,502,367 | [['B01.050'], ['F01.145.113'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.649.313.992.550'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750',... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development. | The activation of natural killer (NK) cells depends on a change in the balance of signals from inhibitory and activating receptors. The activation threshold values of NK cells are thought to be set by engagement of inhibitory receptors during development. Here, we found that the activating receptor NKG2D specifically s... | ['Animals', 'Antigens, Ly', 'Cytotoxicity, Immunologic', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Mice', 'Mice, Knockout', 'NK Cell Lectin-Like Receptor Subfamily K', 'Natural Cytotoxicity Triggering Receptor 1'] | 30,224,819 | [['B01.050'], ['D23.050.301.264.920', 'D23.101.100.920'], ['G12.287'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Loss of the hepatic glycogen-binding subunit (GL) of protein phosphatase 1 underlies deficient glycogen synthesis in insulin-dependent diabetic rats and in adrenalectomized starved rats. | Hepatic glycogen synthesis is impaired in insulin-dependent diabetic rats and in adrenalectomized starved rats, and although this is known to be due to defective activation of glycogen synthase by glycogen synthase phosphatase, the underlying molecular mechanism has not been delineated. Glycogen synthase phosphatase co... | ['Adrenalectomy', 'Animals', 'Carrier Proteins', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 1', 'Liver', 'Liver Glycogen', 'Male', 'Phosphoprotein Phosphatases', 'Protein Phosphatase 1', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Starvation', 'Structure-Activity Relationship'] | 9,657,963 | [['E04.270.115'], ['B01.050'], ['D12.776.157'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['A03.620'], ['D05.750.078.562.388.518', 'D09.698.365.388.518'], ['D08.811.277.352.650.625'], ['D08.811.277.352.650.625.687'], ['D13.444.735.544'], ['B01.050.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The cytochochleogram in atoxyl-treated guinea pigs. | The earliest atoxyl induced changes in the cochlea appeared in the upper and medial parts of the 4th coil, whence the changes spread progressively downwards towards the round window, the extent of the changes depending on the amount of atoxyl administered and the duration of the treatment. The inner hair cells were mor... | ['Aminobenzoates', 'Aniline Compounds', 'Animals', 'Arsenicals', 'Body Weight', 'Cochlea', 'Dose-Response Relationship, Drug', 'Guinea Pigs', 'Lethal Dose 50'] | 948,987 | [['D02.241.223.100.050', 'D02.455.426.559.389.127.020'], ['D02.092.146'], ['B01.050'], ['D01.075', 'D02.129'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A09.246.300.246'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of crossbreeding on collagen solubility and tenderness of Infraspinatus and Semimembranosus muscles of semi-intensively reared young bulls. | The aim of the present study was to investigate the effects of crossbreeding on collagen content and solubility, shear force (WBSF) and the eating quality of Infraspinatus (INF) and Semimembranosus (SM) muscles of young bulls and the relationships between collagen content and solubility, shear force and the eating qual... | ['Animals', 'Cattle', 'Collagen', 'Food Quality', 'Humans', 'Hybridization, Genetic', 'Male', 'Meat', 'Muscle, Skeletal', 'Quantitative Trait, Heritable', 'Shear Strength', 'Solubility', 'Taste', 'Water'] | 26,805,717 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280', 'D12.776.860.300.250'], ['J01.576.423.850.730', 'N06.850.601'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.820.150.390', 'G05.090.390'], ['G07.203.300.600', 'J02.500.600'], ['A02.633.567', 'A10.690.552.500'], ['G05.420.720'], ['G01.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Optimization of Milk sterilization apparatus (author's transl)]. | Referring to a typical plant for milk sterilization fixed and variable costs are evaluated at different heat recovery levels. The results of the analysis indicate that the transformation cost significantly decreases increasing heat recovery, and reaches a minimum at 90% heat regeneration. Milk sterilization apparatuses... | ['Dairying', 'Sterilization'] | 989,618 | [['J01.040.246'], ['N06.850.780.200.450.850']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Evaluation of the short- and long-term safety and therapy outcomes of the everolimus-eluting bioresorbable vascular scaffold system in patients with coronary artery stenosis: Rationale and design of the German-Austrian ABSORB RegIstRy (GABI-R). | BACKGROUND: Third-generation drug-eluting metal stents are the gold standard for treatment of coronary artery disease. The permanent metallic caging of the vessel, however, can result in limited vasomotion, chronic inflammation, and late expansive remodeling, conditions that can lead to late and very late stent thrombo... | ['Absorbable Implants', 'Austria', 'Cohort Studies', 'Coronary Stenosis', 'Drug-Eluting Stents', 'Everolimus', 'Germany', 'Humans', 'Prospective Studies', 'Registries', 'Research Design', 'Treatment Outcome'] | 26,431,767 | [['E07.695.025'], ['Z01.542.088'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['E07.695.750.500'], ['D02.540.505.760.500'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Proteolytic Digestion and TiO2 Phosphopeptide Enrichment Microreactor for Fast MS Identification of Proteins. | The characterization of phosphorylation state(s) of a protein is best accomplished by using isolated or enriched phosphoprotein samples or their corresponding phosphopeptides. The process is typically time-consuming as, often, a combination of analytical approaches must be used. To facilitate throughput in the study of... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'Cell Line, Tumor', 'Humans', 'Phosphopeptides', 'Phosphoproteins', 'Phosphorylation', 'Proteolysis', 'Proteomics', 'Silicon Dioxide', 'Spectrometry, Mass, Electrospray Ionization', 'Titanium'] | 26,883,530 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.717'], ['D12.776.744'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G02.111.720', 'G03.812'], ['H01.158.201.843', 'H01.15... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma. | BACKGROUND: Advanced melanoma patients have an extremely poor long term prognosis and are in strong need of new therapies. The recently developed targeted therapies have resulted in a marked antitumor effect, but most responses are partial and some degree of toxicity remain the major concerns. Dendritic cells play a ke... | ['Adult', 'Aged', 'Antigens, Neoplasm', 'Cancer Vaccines', 'Combined Modality Therapy', 'Dacarbazine', 'Dendritic Cells', 'Drug Therapy', 'Female', 'Gene Expression Profiling', 'Humans', 'Immunotherapy', 'Injections, Intralesional', 'Interferon-alpha', 'Leukocytes, Mononuclear', 'Male', 'Melanoma', 'Membrane Proteins',... | 25,933,939 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['D20.215.894.200'], ['E02.186'], ['D02.925.200', 'D03.383.129.308.240'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['E02.319'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['E02.319.267.530.43... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cardiac dysrhythmias during oral surgery: effect of combined local and general anaesthesia. | In two groups, each of 50 patients undergoing oral surgery, effects of combining lidocaine nerve block with halothane general anaesthesia were studied. Local blockade of surgical stimuli reduced markedly the incidence of cardiac dysrhythmias occurred during halothane anaesthesia. Recovery was faster and post-operative ... | ['Adolescent', 'Adult', 'Anesthesia Recovery Period', 'Anesthesia, Dental', 'Anesthesia, General', 'Anesthesia, Local', 'Arrhythmias, Cardiac', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Double-Blind Method', 'Drug Combinations', 'Female', 'Halothane', 'Humans', 'Lidocaine', 'Male', 'Nerve Block'] | 2,337,559 | [['M01.060.057'], ['M01.060.116'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E03.155.141', 'E06.045'], ['E03.155.197'], ['E03.155.086.231'], ['C14.280.067', 'C23.550.073'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants. | Many pharmacologically important receptors, including all cytokine receptors, signal via tyrosine (auto)phosphorylation, followed by resetting to their original state through the action of protein tyrosine phosphatases (PTPs). Establishing the specificity of PTPs for receptor substrates is critical both for understandi... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Collodion', 'DNA, Complementary', 'Humans', 'Molecular Sequence Data', 'Mutagenesis', 'Phosphorylation', 'Protein Tyrosine Phosphatases', 'Receptor, Insulin', 'Substrate Specificity'] | 10,734,133 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['D25.720.099.500.439', 'J01.637.051.720.099.500.439'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G05.558'], ['G02.111.665', 'G02.607.780', 'G03.796'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Late initiation of antenatal care and associated factors among pregnant women in Addis Zemen primary hospital, South Gondar, Ethiopia. | BACKGROUND: Antenatal care (ANC) is special care for pregnant women with the aim of preventing, detecting and treating health problems in both the fetus and mother. Early ANC attendance promotes early detection and treatment of complications which result in proper management during delivery and puerperium. However, the... | ['Adult', 'Cross-Sectional Studies', 'Ethiopia', 'Female', 'Health Facilities', 'Health Promotion', 'Humans', 'Maternal Health Services', 'Office Visits', 'Patient Acceptance of Health Care', 'Pregnancy', 'Pregnant Women', 'Prenatal Care', 'Young Adult'] | 31,151,402 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.290.120.310'], ['N02.278'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.143.620', 'N02.421.800.500'], ['N04.452.758.635'], ['F01.100.150.750.500', 'F01.14... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Citrate synthase from the hyperthermophilic Archaeon, Pyrococcus furiosus. | The gene encoding the enzyme citrate synthase has been cloned and sequenced from the hyperthermophilic Archaeon Pyrococcus furiosus, and the derived amino acid sequence has been phylogenetically compared with citrate synthases from archaeal, bacterial and eukaryal organisms. The gene has been over-expressed in Escheric... | ['Amino Acid Sequence', 'Archaea', 'Base Sequence', 'Citrate (si)-Synthase', 'Cloning, Molecular', 'DNA, Bacterial', 'Enzyme Stability', 'Escherichia coli', 'Hot Temperature', 'Kinetics', 'Models, Molecular', 'Molecular Sequence Data', 'Sequence Homology, Amino Acid'] | 8,532,683 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B02'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.050.368'], ['E05.393.220'], ['D13.444.308.212'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Development and Early Piloting of a CanMEDS Competency-Based Feedback Tool for Surgical Grand Rounds. | OBJECTIVE: Grand rounds offer an excellent opportunity for the evaluation of medical expertise, and other competencies, such as communication and professionalism. The purpose of this study was to develop a tool that would facilitate the provision of formative feedback for grand rounds to improve learning. The resulting... | ['Adult', 'Clinical Competence', 'Competency-Based Education', 'Education, Medical, Graduate', 'Educational Measurement', 'Feedback', 'Female', 'Humans', 'Internship and Residency', 'Male', 'Ontario', 'Orthopedics', 'Pilot Projects', 'Program Evaluation', 'Teaching Rounds'] | 26,896,145 | [['M01.060.116'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158.210'], ['I02.358.337.350', 'I02.358.399.350'], ['I02.399'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['Z01.107.567.176.639'], ['H02.403.810.494'], ['E05.318.372.750... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
The modulation of adiponectin by STAT5-activating hormones. | Adiponectin is a hormone secreted from adipocytes that plays an important role in insulin sensitivity and protects against metabolic syndrome. Growth hormone (GH) and prolactin (PRL) are potent STAT5 activators that regulate the expression of several genes in adipocytes. Studies have shown that the secretion of adipone... | ['3T3-L1 Cells', 'Adipocytes', 'Adiponectin', 'Animals', 'Growth Hormone', 'Mice', 'Prolactin', 'Promoter Regions, Genetic', 'STAT5 Transcription Factor'] | 26,601,851 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['B01.050'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.992.635.505.500'], ['D06.472.699.322.5... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The cytokine-driven regulation of secretoglobins in normal human upper airway and their expression, particularly that of uteroglobin-related protein 1, in chronic rhinosinusitis. | BACKGROUND: The involvement of secretoglobins (SCGBs) other than SCGB1A1 (Clara cell 10-kDa protein, CC10) in human airway diseases remains unexplored. Among those SCGBs, SCGB3A2 (uteroglobin-related protein 1, UGRP1) is particularly interesting, given its structure and function similarities with SCGB1A1 (CC10). The ai... | ['Adult', 'Chronic Disease', 'Cytokines', 'Down-Regulation', 'Female', 'Humans', 'Immunohistochemistry', 'Inflammation Mediators', 'Male', 'Middle Aged', 'Nasal Mucosa', 'Nasal Polyps', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Rhinitis', 'Secretoglobins', 'Sinusitis', 'Time Factors', 'Tissu... | 21,385,388 | [['M01.060.116'], ['C23.550.291.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.1... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The association between RhoB and caspase-2: changes with lovastatin-induced apoptosis. | Because cytoskeletal actin is regulated, in part, by Rho, and because Rho and caspases are involved in apoptosis, we sought to determine whether there was an association between RhoB and caspase-2. A RhoB-caspase-2 association was consistently demonstrated in neonatal mouse cardiomyocytes with Western Blotting, either ... | ['Actins', 'Animals', 'Apoptosis', 'Blotting, Western', 'Caspase 2', 'Caspases', 'Cells, Cultured', 'Immunohistochemistry', 'Lovastatin', 'Mice', 'Protein Binding', 'rhoB GTP-Binding Protein'] | 16,234,849 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126.550.200', 'D08.811.277.656.300.200.126.550.200', 'D12.644.360.075.405.550.200', 'D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
SOD1 mutations in amyotrophic lateral sclerosis. Results from a multicenter Italian study. | Amyotrophic Lateral Sclerosis (ALS), the most common form among motoneuron diseases, is characterized by a progressive neurodegenerative process involving motor neurons in the motor cortex, brain stem and spinal cord. Sporadic (SALS) accounts for the majority of patients but in about 10% of ALS cases the disease is inh... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Amyotrophic Lateral Sclerosis', 'Blotting, Northern', 'Cohort Studies', 'DNA Mutational Analysis', 'Exons', 'Family Health', 'Female', 'Genotype', 'Glycine', 'Humans', 'Introns', 'Italy', 'Male', 'Middle Aged', 'Mutation', 'Pedigree', 'Polymorphism, Genetic', 'RNA, ... | 15,789,135 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ammonium reduces chromium toxicity in the freshwater alga Chlorella vulgaris. | The aim of the present study was to investigate the protective effect of ammonium (NH4 (+)) on Cr toxicity to the freshwater alga Chlorella vulgaris. We followed an array of cellular functions and biomolecules in C. vulgaris cells exposed to 50 or 100 ìM Cr at three different initial NH4 (+) concentrations (0.5, 3, and... | ['Ammonium Compounds', 'Chlorella vulgaris', 'Chlorine', 'Chlorophyll', 'Chromium', 'Dose-Response Relationship, Drug', 'Fresh Water', 'Gene Expression Regulation, Plant', 'Phosphorus', 'Photosynthesis', 'Sulfur', 'Water Pollutants, Chemical'] | 25,421,561 | [['D01.625.062'], ['B01.650.940.150.469.400'], ['D01.268.380.150', 'D01.362.225'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['G07.690.773.875', 'G07.690.936.500'], ['G16.500.275.280', 'N06.230.232'], ['G05.308.375'], ['D01.268.666'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Interactions among filamentous fungi Aspergillus niger, Fusarium verticillioides and Clonostachys rosea: fungal biomass, diversity of secreted metabolites and fumonisin production. | BACKGROUND: Interactions among fungi colonizing dead organic matter involve exploitation competition and interference competition. Major mechanism of interference competition is antibiosis caused by secreted secondary metabolites. The effect of competition on secondary metabolite production by fungi is however poorly u... | ['Antibiosis', 'Asparagine', 'Aspergillus niger', 'Biomass', 'Coculture Techniques', 'Culture Media', 'Fumonisins', 'Fusarium', 'Genetic Fitness', 'Hypocreales', 'Secondary Metabolism', 'Species Specificity'] | 27,165,654 | [['G06.550.050', 'G16.062'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['B01.300.381.081.450'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E05.481.500.374'], ['D27.720.470.305', 'E07.206'], ['D02.455.326.146.432', 'D23.946.587.385'], ['B01.300.381.366'], ['G05.347'], ['B01.300.107.501'], ['G03.493.8... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Angiotensin-converting enzyme gene polymorphism as a potent risk factor for developing microalbuminuria in Japanese patients with type 2 diabetes mellitus: a 9-year follow-up study. | To clarify the risk factors for developing microalbuminuria in patients with type 2 diabetes mellitus, a longitudinal observational study was performed. Fifty patients with normoalbuminuria were recruited and treated conventionally for 9 years. Polymorphisms of the angiotensin-converting enzyme (ACE) gene and the angio... | ['Adult', 'Aged', 'Albuminuria', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Gene Frequency', 'Genotype', 'Humans', 'Japan', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Peptidyl-Dipeptidase A', 'Polymorphism, Genetic', 'Regression Analysis', 'Risk Factors'] | 12,964,504 | [['M01.060.116'], ['M01.060.116.100'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Separation and characterization of the colloidal phases produced on digestion of common formulation lipids and assessment of their impact on the apparent solubility of selected poorly water-soluble drugs. | Colloidal mixtures containing bile salts (BS), phosphatidylcholine (PC), and medium and long-chain monoglycerides and fatty acids were prepared as model systems to represent typical intestinal contents after digestion of formulation derived lipids under both low (5 mM BS/1.25 mM PC) and high (20 mM BS/5 mM PC) BS and P... | ['Chemistry, Pharmaceutical', 'Colloids', 'Lipids', 'Pharmaceutical Preparations', 'Solubility', 'Water'] | 12,587,125 | [['H01.158.703.007', 'H01.181.466'], ['D20.280', 'D26.255.165'], ['D10'], ['D26'], ['G02.805'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone marrow stromal cells can achieve cure of chronic paraplegic rats: functional and morphological outcome one year after transplantation. | Chronic paraplegia resulting from severe spinal cord injury (SCI) is considered to be an irreversible condition. Nevertheless, recent studies utilizing adult stem cells appear to offer promise in the treatment of this and other neurological diseases. Here, we show that progressive functional motor recovery is achieved ... | ['Animals', 'Bone Marrow Cells', 'Bone Marrow Transplantation', 'Chronic Disease', 'Disease Models, Animal', 'Female', 'Immunohistochemistry', 'Nerve Tissue Proteins', 'Paraplegia', 'Rats', 'Rats, Wistar', 'Recovery of Function', 'Spinal Cord Injuries', 'Stromal Cells', 'Time Factors', 'Tyrosine 3-Monooxygenase', 'beta... | 16,713,677 | [['B01.050'], ['A11.148', 'A15.378.316'], ['E02.095.147.725.040', 'E04.936.580.040'], ['C23.550.291.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', ... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Fibrotic contracture of the canine infraspinatus muscle: pathophysiology and prevention by early surgical intervention. | Fibrotic contracture of the canine infraspinatus muscle (FCIM) is considered a rare musculotendineous disorder mainly affecting hunting dogs. After an acute onset of a painful non-weight bearing lameness, the initial pain and lameness improve over a period of one to four weeks, after which a characteristic circumducted... | ['Animals', 'Contracture', 'Dog Diseases', 'Dogs', 'Fibrosis', 'Forelimb', 'Immunohistochemistry', 'Lameness, Animal', 'Male', 'Muscle, Skeletal', 'Pain', 'Rupture', 'Treatment Outcome'] | 16,810,356 | [['B01.050'], ['C05.550.323', 'C05.651.197'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C23.550.355'], ['A13.395'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Evidence for widespread adaptive evolution of gene expression in budding yeast. | Changes in gene expression have been proposed to underlie many, or even most, adaptive differences between species. Despite the increasing acceptance of this view, only a handful of cases of adaptive gene expression evolution have been demonstrated. To address this discrepancy, we introduce a simple test for lineage-sp... | ['Adaptation, Biological', 'Ergosterol', 'Evolution, Molecular', 'Gene Expression Regulation, Fungal', 'Genetics, Population', 'Models, Genetic', 'Quantitative Trait Loci', 'Saccharomyces cerevisiae', 'Selection, Genetic'] | 20,133,628 | [['G16.012'], ['D04.210.500.247.222.537'], ['G05.045.250', 'G16.075.250'], ['G05.308.330'], ['H01.158.273.343.335'], ['E05.599.395.397'], ['G05.360.340.024.380.937'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['G05.783']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cdx2 represses Oct4 function via inducing its proteasome-dependent degradation in early porcine embryos. | Reciprocal repression of inner cell mass specific factor OCT4 and trophectoderm specific factor CDX2 promotes mouse first lineage segregation. Studies in mouse embryonic stem (ES) cells revealed that they bind to each other's regulatory regions to reciprocally suppress transcription, additionally they form protein comp... | ['Active Transport, Cell Nucleus', 'Animals', 'Cells, Cultured', 'Homeodomain Proteins', 'Leupeptins', 'Octamer Transcription Factors', 'Proteasome Endopeptidase Complex', 'RNA, Messenger', 'Swine'] | 26,708,097 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.050'], ['A11.251'], ['D12.776.260.400'], ['D12.644.456.580'], ['D12.776.260.655.500', 'D12.776.930.710.500'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['D13.444.735.544'], ['B01.050.150.900.649.313.500.880']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway. | Resveratrol, a natural phenolic compound, provides neuroprotective effects, however, the specific mechanisms of action remain to be elucidated. The purpose of the present study was to examine the neuroprotective effect of resveratrol on spinal cord injury (SCI) and the potential molecular mechanisms of action. A rat mo... | ['AMP-Activated Protein Kinases', 'Animals', 'Autophagy', 'Inflammation', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Resveratrol', 'Signal Transduction', 'Spinal Cord Injuries', 'Stilbenes', 'TOR Serine-Threonine Kinases'] | 29,956,767 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['B01.050'], ['G04.011'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D02.455.426.559.389.150.700.725.875', 'D02.455.426.559.389.657.715.500'], ['G02.111.820', 'G04.835'], ['C... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unveiling Inherent Degeneracies in Determining Population-Weighted Ensembles of Interdomain Orientational Distributions Using NMR Residual Dipolar Couplings: Application to RNA Helix Junction Helix Motifs. | A growing number of studies employ time-averaged experimental data to determine dynamic ensembles of biomolecules. While it is well-known that different ensembles can satisfy experimental data to within error, the extent and nature of these degeneracies, and their impact on the accuracy of the ensemble determination re... | ['Base Sequence', 'Entropy', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Nucleic Acid Conformation', 'Nucleotide Motifs', 'RNA'] | 26,131,693 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G01.906.345'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570.820.486', 'G05.360.580'], ['G02.111.570.080.611', 'G02.111.570.820.486.662', 'G05.360.080.611', 'G05.360.580.662'], ['D13.444.735']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sympathetic innervation-mediating protein. | The present study was performed to elucidate the mechanisms and molecular basis of specific innervation of the peripheral tissues. Chick sympathetic nerve fibers densely innervate expansor secundariorum muscle, but not skeletal muscle. When a sympathetic ganglion was cultured in collagen gel with muscle explants, the g... | ['Animals', 'Axons', 'Cell Adhesion', 'Chick Embryo', 'Culture Media', 'Embryonic and Fetal Development', 'Fluorescence', 'Ganglia, Sympathetic', 'Histocytochemistry', 'Immune Sera', 'Molecular Weight', 'Muscles', 'Nerve Tissue Proteins', 'Sympathetic Nervous System', 'Wings, Animal'] | 2,259,481 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G04.022'], ['A13.350.150', 'A16.331.200'], ['D27.720.470.305', 'E07.206'], ['G07.345.500.325', 'G08.686.784.170'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Viral pathogens among elderly people with acute respiratory infections in Shanghai, China: Preliminary results from a laboratory-based surveillance, 2012-2015. | Acute respiratory infections (ARIs), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. The clinical and pathological features of elderly people with ARIs need to be identified for disease intervention. From Jan... | ['Aged', 'Aged, 80 and over', 'China', 'Clinical Laboratory Techniques', 'Coinfection', 'Epidemiological Monitoring', 'Female', 'Human bocavirus', 'Humans', 'Influenza, Human', 'Male', 'Metapneumovirus', 'Middle Aged', 'Multiplex Polymerase Chain Reaction', 'Outpatients', 'Public Policy', 'Respiratory Syncytial Virus, ... | 27,943,329 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.252.474.164'], ['E01.370.225', 'E05.200'], ['C01.218'], ['E05.318.375', 'N06.850.520.460'], ['B04.280.580.650.085.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['B04.820.480.937.600.670.500'], ['M01.060... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
An Osmotic Membrane Bioreactor-Membrane Distillation System for Simultaneous Wastewater Reuse and Seawater Desalination: Performance and Implications. | In this study, we demonstrate the potential of an osmotic membrane bioreactor (OMBR)-membrane distillation (MD) hybrid system for simultaneous wastewater reuse and seawater desalination. A stable OMBR water flux of approximately 6 L m-2 h-1 was achieved when using MD to regenerate the seawater draw solution. Water prod... | ['Bioreactors', 'Distillation', 'Membranes, Artificial', 'Osmosis', 'Seawater', 'Waste Water', 'Water Purification'] | 29,135,240 | [['E07.115', 'J01.897.120.115'], ['E05.196.155.249'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['G16.500.275.725.500'], ['D20.944.932', 'N06.850.460.710.865'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Port-A-Cath insertions in acute leukaemia and childhood malignancies. | OBJECTIVE: This retrospective case series sought to determine the incidence and profile of catheter-related complications associated with Port-A-Cath insertions in paediatric cancer patients, as well as predictive factors for infection-related port removals.METHODS: Between January 2002 and December 2004, 175 consecuti... | ['Adolescent', 'Catheterization, Central Venous', 'Catheters, Indwelling', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Incidence', 'Infant', 'Male', 'Neoplasms', 'Predictive Value of Tests', 'Retrospective Studies', 'Risk Factors', 'Sepsis'] | 17,638,639 | [['M01.060.057'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E07.132.500'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Attitudes toward life-sustaining interventions among ambulatory black and white patients. | OBJECTIVES: The purpose of this study was to evaluate racial differences in preference for life-sustaining interventions in the context of various physical and mental health scenarios.DESIGN: Data were collected by using an investigator-administered survey.SETTING AND PATIENTS: Consecutive patients who self-identified ... | ['African Americans', 'Aged', 'Attitude to Death', 'Confounding Factors, Epidemiologic', 'Cross-Cultural Comparison', 'Decision Making', 'Disabled Persons', 'European Continental Ancestry Group', 'Female', 'Humans', 'Life Support Care', 'Linear Models', 'Living Wills', 'Male', 'Middle Aged', 'Multivariate Analysis', 'N... | 17,061,746 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['F01.100.125', 'N05.300.125'], ['N05.715.350.240', 'N06.850.490.718'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['F02.463.785.373'], ['M01.150'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.440', 'N02.421.585.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
On the determination of ventilatory threshold and respiratory compensation point via respiratory frequency. | This study examined the validity of a quantitative respiratory frequency (f(R)) analysis to detect the ventilatory threshold (theta(Vent)) and respiratory compensation point (RCP). Thirty-six amateur competitive cyclists completed a maximal graded exercise test on an electromagnetically-braked cycle ergometer. theta(Ve... | ['Adult', 'Bias', 'Bicycling', 'Electromagnetic Phenomena', 'Exercise Test', 'Female', 'Humans', 'Lactic Acid', 'Linear Models', 'Male', 'Pulmonary Gas Exchange', 'Pulmonary Ventilation', 'Young Adult'] | 19,130,393 | [['M01.060.116'], ['N05.715.350.150', 'N06.850.490.500'], ['I03.450.642.845.140'], ['G01.358.500'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Congenital left ventricular diverticulum in an adult patient. | A 64-year-old woman was referred to our hospital with palpitation and exertional dyspnea. An electrocardiogram showed sinus rhythm, but supraventricular tachycardia was recorded on Holter monitoring. Multidetector computed tomography revealed a small left ventricular outpouching in the apex, with a narrow connection to... | ['Biopsy', 'Diverticulum', 'Electrocardiography, Ambulatory', 'Female', 'Heart Aneurysm', 'Heart Defects, Congenital', 'Heart Ventricles', 'Humans', 'Middle Aged', 'Multidetector Computed Tomography', 'Treatment Outcome', 'Ventricular Function, Left'] | 27,095,703 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C06.405.205.282.750', 'C23.300.415'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['C14.280.358', 'C14.907.055.608'], ['C14.240.400', 'C14.280.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Constructing naive Bayesian classifiers for veterinary medicine: a case study in the clinical diagnosis of classical swine fever. | For diseases of which the clinical diagnosis is uncertain, naive Bayesian classifiers can be of assistance to the veterinary practitioner. These simple probabilistic models have proven to be very powerful for solving classification problems in a variety of domains, but are not yet widely applied within the veterinary d... | ['Animals', 'Bayes Theorem', 'Classical Swine Fever', 'Diagnosis, Differential', 'Sensitivity and Specificity', 'Swine', 'Veterinary Medicine'] | 20,817,220 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C01.925.782.350.675.200', 'C22.905.170'], ['E01.171'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['B01.050.150.900.649.313.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
MIF-1 does not act like naloxone in antagonizing the cardiovascular activity of leucine-enkephalin in the conscious dog. | MIF-1 (Pro-Leu-Gly-NH2), a hypothalamic tripeptide, has been demonstrated to stimulate naloxone in antagonizing the effects of opioid peptides in a number of experimental systems including enkephalin-induced analgesia in the tail-flick assay, beta-endorphin induced hypothermia and hypomotility, deprivation-induced drin... | ['Animals', 'Blood Pressure', 'Dogs', 'Enkephalin, Leucine', 'Heart Rate', 'Hypothalamic Hormones', 'MSH Release-Inhibiting Hormone', 'Naloxone', 'Pentobarbital', 'Peptides', 'Receptors, Opioid'] | 6,131,437 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.750.250.216.200'], ['D12.644.400.575.281.231', 'D12.776.631.650.575.281.231'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D06.472.699.327', 'D12.644.400.400', 'D12.644.548.365', 'D12.776.631.650.405'], ['D06.472.699.327.700.500', 'D1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolonged waiting times for liver transplantation in obese patients. | OBJECTIVE: To quantify the independent association between obesity and access to liver transplantation.BACKGROUND: Obesity is associated with higher complication rates, longer hospitalization, and worse survival after liver transplantation. Nevertheless, transplantation provides survival benefit to patients with end-st... | ['Body Mass Index', 'Comorbidity', 'Diabetes Mellitus', 'Fatty Liver', 'Female', 'Health Services Accessibility', 'Hepatitis C', 'Humans', 'Liver Failure', 'Liver Transplantation', 'Male', 'Middle Aged', 'Obesity', 'Obesity, Morbid', 'Patient Selection', 'Regression Analysis', 'Resource Allocation', 'Tissue and Organ P... | 18,948,816 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['N05.715.350.225', 'N06.850.490.687'], ['C18.452.394.750', 'C19.246'], ['C06.552.241'], ['N04.590.374.350', 'N05.300.430'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Walking pattern of patients with hip disorders (author's transl)]. | The purpose of the present paper is to investigate the walking pattern of patients with hip disorders. The materials consist of 37 cases of osteoarthritis, ten cases of fused hips and two cases of congenital hip dislocation which had not been treated. Of the 37 cases with osteoarthritis, seven cases were in pre-arthros... | ['Adolescent', 'Adult', 'Female', 'Gait', 'Hip Dislocation, Congenital', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis'] | 7,310,207 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606', 'C05.799.613']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[New pathways in the treatment of psychologically drug dependent adolescents]. | Based on a one-and-half year experience in a small group setting with drug dependent adolescents the change of group structure, the functioning of the group for its members, the leader's position within the group and the therapeutic relationship are analysed. In its beginning the group develops what can be called a "sy... | ['Adolescent', 'Autogenic Training', 'Ego', 'Emotions', 'Humans', 'Physician-Patient Relations', 'Psychotherapy, Group', 'Substance-Related Disorders'] | 478,416 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Validity and reliability of functional assessment of chronic illness treatment-fatigue scale in Turkish patients with type 2 diabetes. | BACKGROUND: A long-term diabetic complication, fatigue, which is a direct result of treatment and psychological processes, is a common symptom in diabetic individuals.AIMS: To determine the reliability and validity of Functional Assessment of Chronic Illness Treatment-Fatigue Scale in Turkish patients with type 2 diabe... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chronic Disease', 'Diabetes Complications', 'Diabetes Mellitus, Type 2', 'Fatigue', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Turkey'] | 29,685,730 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.500'], ['C19.246.099'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['Z01.252... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ketamine and midazolam for invasive procedures in children with malignancy: a comparison of routes of intravenous, oral, and rectal administration. | We investigated the efficacy of a combination of ketamine and midazolam, comparing intravenous, oral, and rectal administrations for invasive procedures in children with malignancy. Seventy-three children under 5 years of age, who were scheduled for invasive procedure, were assigned to one of three groups: IV group (n ... | ['Administration, Oral', 'Administration, Rectal', 'Anesthesia Recovery Period', 'Anesthetics, Combined', 'Anesthetics, Dissociative', 'Blood Pressure', 'Child, Preschool', 'Female', 'Heart Rate', 'Humans', 'Hypnotics and Sedatives', 'Injections, Intravenous', 'Ketamine', 'Male', 'Midazolam', 'Neoplasms'] | 15,357,562 | [['E02.319.267.100'], ['E02.319.267.120.655.750'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['D27.505.696.277.100.017', 'D27.505.954.427.210.100.017'], ['D27.505.696.277.100.035.075.035', 'D27.505.954.427.210.100.035.075.035'], ['E01.370.600.875.249', 'G09.330.380.076'], ['M01.060.406.448'], ['E01.370... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Tuberculosis in refugees from foreign countries]. | Screening for tuberculosis has revealed active disease in 30 of 168 examinees. They have arrived in Russia as refugees from Somalia, Afghanistan, Angola and other countries. 24 refugees had pulmonary tuberculosis. Destruction of pulmonary tissues and massive discharge of M. tuberculosis were found in 10, 2 and 1 patien... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Refugees', 'Russia', 'Tuberculosis', 'Tuberculosis, Lymph Node', 'Tuberculosis, Pulmonary'] | 8,754,866 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.755'], ['Z01.252.122.500', 'Z01.542.248.775'], ['C01.150.252.410.040.552.846'], ['C01.150.252.410.040.552.846.719'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Long non-coding RNAs within the tumour microenvironment and their role in tumour-stroma cross-talk. | Long non-coding RNAs (lncRNAs) are a diverse class of RNA transcripts which have limited protein coding potential. They perform a variety of cellular functions in health, but have also been implicated during malignant transformation. A further theme in recent years is the critical role of the tumour microenvironment an... | ['Disease Progression', 'Extracellular Matrix', 'Humans', 'Neoplasms', 'RNA, Long Noncoding', 'Signal Transduction', 'Stromal Cells', 'Tumor Microenvironment'] | 29,458,141 | [['C23.550.291.656'], ['A11.284.295.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['D13.444.735.790.375'], ['G02.111.820', 'G04.835'], ['A11.329.830'], ['G04.366.500']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predicting sustained viral response to hepatitis C using a rapid and simple IL28B rs8099917 genotyping assay. | Recent studies showed that two single nucleotide polymorphisms (SNPs) (rs12979860 and rs8099917) near the gene IL28B coding for IFNë3 were associated with the antiviral treatment response of the combination therapy of pegIFN plus RBV. We established the use of tetra-primer amplification refractory mutation system polym... | ['Adult', 'Animals', 'Antiviral Agents', 'Asian Continental Ancestry Group', 'Base Sequence', 'China', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Interferon-alpha', 'Interferons', 'Interleukins', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Polymorphism, Single Nucleotide', 'Treatment... | 22,387,386 | [['M01.060.116'], ['B01.050'], ['D27.505.954.122.388'], ['M01.686.508.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.474.164'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Facilitated permeation of antibiotics across membrane channels--interaction of the quinolone moxifloxacin with the OmpF channel. | The facilitated influx of moxifloxacin through the most abundant channel in the outer cell wall of gram-negative bacteria was investigated. Molecular modeling provided atomic details of the interaction with the channel surface, revealed the preferred orientation of the antibiotic along its pathway, and gave an estimate... | ['Anti-Bacterial Agents', 'Aza Compounds', 'Fluoroquinolones', 'Models, Molecular', 'Moxifloxacin', 'Porins', 'Protein Binding', 'Protein Structure, Tertiary', 'Quinolines', 'Quinolones', 'Spectrometry, Fluorescence'] | 18,788,798 | [['D27.505.954.122.085'], ['D02.145'], ['D03.633.100.810.835.322'], ['E05.599.595'], ['D03.633.100.810.835.322.327'], ['D12.776.157.530.400.500', 'D12.776.543.550.450.730', 'D12.776.543.585.400.730'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.610'], ['D03.633.100.810'], ['D03.633.100.810.835'], ['E05.196.712.51... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Flow cytoenzymology of intracellular tartrate-resistant acid phosphatase. | Tartrate-resistant acid phosphatase (TRACP) is a cytochemical marker for hairy cell leukemia, macrophages, dendritic cells, and osteoclasts. Our purpose was to develop multicolor cytofluorometric methods to evaluate intracellular TRACP enzymic activity using a fluorogenic cytochemical reaction in combination with immun... | ['Acid Phosphatase', 'Biomarkers', 'Cells, Cultured', 'Dendritic Cells', 'Flow Cytometry', 'Humans', 'Immunoassay', 'Intracellular Fluid', 'Isoenzymes', 'Tartrate-Resistant Acid Phosphatase'] | 12,923,238 | [['D08.811.277.352.650.025'], ['D23.101'], ['A11.251'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene-by-diet interactions influence calcium absorption and bone density in mice. | Dietary calcium (Ca) intake is needed to attain peak bone mineral density (BMD). Habitual low Ca intake increases intestinal Ca absorption efficiency to protect bone mass, but the mechanism controlling, and the impact of genetics on, this adaptive response is not clear. We fed 11 genetically diverse inbred mouse lines ... | ['Animals', 'Bone Density', 'Calcium, Dietary', 'Intestinal Absorption', 'Kidney', 'Male', 'Mice', 'Mice, Inbred Strains', 'Principal Component Analysis', 'RNA, Messenger'] | 23,955,923 | [['B01.050'], ['G11.427.100'], ['D01.146.395'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['E05.318... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health resource utilization and clinical outcomes with risperidone therapy in patients with serious mental illness. | This report is an analysis of our experience with risperidone therapy in a veteran population with severe, suboptimally responsive psychosis from a perspective of clinical response and health resource utilization. We conducted a computer search for all patients who received risperidone therapy at our facility from Febr... | ['Antipsychotic Agents', 'Combined Modality Therapy', 'Dose-Response Relationship, Drug', 'Female', 'Hospitals, Veterans', 'Humans', 'Length of Stay', 'Male', 'Mental Disorders', 'Middle Aged', 'Ohio', 'Psychiatric Department, Hospital', 'Retrospective Studies', 'Risperidone', 'Severity of Illness Index', 'Time Factors... | 10,360,614 | [['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E02.186'], ['G07.690.773.875', 'G07.690.936.500'], ['N02.278.421.510.180.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['F03'], ['M01.060.116.630'], ['Z01.107.567.875.075.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Improving Registration Robustness for Image-Guided Liver Surgery in a Novel Human-to-Phantom Data Framework. | In open image-guided liver surgery (IGLS), a sparse representation of the intraoperative organ surface can be acquired to drive image-to-physical registration. We hypothesize that uncharacterized error induced by variation in the collection patterns of organ surface data limits the accuracy and robustness of an IGLS re... | ['Algorithms', 'Hepatectomy', 'Humans', 'Liver', 'Phantoms, Imaging', 'Surgery, Computer-Assisted'] | 28,212,080 | [['G17.035', 'L01.224.050'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E07.671'], ['E04.749']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Association between regional deprivation and type 2 diabetes incidence in Germany. | Objective: The aim of this analysis was to estimate the association between regional deprivation and type 2 diabetes incidence and to investigate differences by age and sex for Germany.Research design and methods: Type 2 diabetes incidence rate ratios comparing the most deprived fifth of the population to the remainder... | ['Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Germany', 'Health Status Disparities', 'Humans', 'Male', 'Middle Aged', 'Poverty Areas', 'Prevalence', 'Prognosis', 'Risk Factors', 'Socioeconomic Factors', 'Survival Rate', 'Young Adult'] | 31,908,802 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The development of visual functions in children]. | Visual function is based on the eye, but it is thanks to the cognitive processing of sensory information that the individual adapts his behaviour and gaze. Visual maturation is acquired gradually over the first 3 years. That is why it is important to detect any visual disorder before the age of 3. | ['Child', 'Child Development', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Vision, Ocular'] | 21,853,809 | [['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Normal findings and pathological changes of the patellar ligament in the computer tomogram]. | In the computer tomogram, the normal patellar ligament appears as a flat band with an average density of 110 HE. After trauma and also after chronic overloading, the cross-section increases, whereas the density decreases. CT is superior to conventional x-ray diagnosis and to sonography in respect of detecting and diffe... | ['Adult', 'Aged', 'Cartilage Diseases', 'Humans', 'Ligaments, Articular', 'Middle Aged', 'Patella', 'Postoperative Complications', 'Tomography, X-Ray Computed'] | 4,017,441 | [['M01.060.116'], ['M01.060.116.100'], ['C05.182', 'C17.300.182'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['M01.060.116.630'], ['A02.835.232.043.650.624', 'A02.835.232.730.500'], ['C23.550.767'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuropeptide production by small cell carcinoma: vasopressin and oxytocin as plasma markers of disease. | Vasopressin (VP) and oxytocin (OT) were evaluated as tumor markers for small cell carcinoma of the lung by measuring the concentrations of these hormones in plasma samples obtained from patients at the onset of therapy and during treatment. Patient levels of VP before treatment ranged from 0.9-116 pmol/L, and this horm... | ['Adult', 'Biomarkers, Tumor', 'Carcinoma, Small Cell', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neuropeptides', 'Neurophysins', 'Oxytocin', 'Reference Values', 'Vasopressins'] | 1,659,583 | [['M01.060.116'], ['D23.101.140'], ['C04.557.470.200.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['D12.644.400', 'D12.776.631.650'], ['D12.644.400.525', 'D12.776.157.597', 'D12.776.631.650.525'], ['D06.472.699.631.692.433', 'D12.644... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pre-and post-mortem MR imaging of unsuspected multiple sclerosis in a patient with Alzheimer's disease. | A patient with the clinical diagnosis of Alzheimer's disease is presented in whom pre-mortem T2-weighted MRI revealed a periventricular white matter lesion. Postmortem T2 weighted MRIs of the formalin fixed brain revealed the same white matter lesion. Microscopically, classical Alzheimer changes were found and, unsuspe... | ['Aged', 'Alzheimer Disease', 'Brain', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Multiple Sclerosis', 'Sensitivity and Specificity'] | 8,410,053 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel framework for evaluating the image accuracy of dynamic MRI and the application on accelerated breast DCE MRI. | OBJECTIVE: To develop a novel framework for evaluating the accuracy of quantitative analysis on dynamic contrast-enhanced (DCE) MRI with a specific combination of imaging technique, scanning parameters, and scanner and software performance and to test this framework with breast DCE MRI with Time-resolved angiography WI... | ['Acceleration', 'Algorithms', 'Breast', 'Breast Neoplasms', 'Computer Simulation', 'Contrast Media', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Models, Statistical', 'Particle Size', 'Phantoms, Imaging', 'Rep... | 28,894,997 | [['G01.482.107'], ['G17.035', 'L01.224.050'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['L01.224.160'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.30... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Anomalous vitamin E effects in mitochondrial oxidative metabolism. | Three different vitamin E effects, suggestive of specific antioxidant effects, were discovered in the protective action of vitamin E against respiratory decline (a decrease in mitochondrial respiration attributed to a "leakage" of electron transport radicals). No correlation was found between respiraotry decline and ra... | ['Acetaldehyde', 'Animals', 'Cell Fractionation', 'Cytosol', 'Ethanol', 'Lipid Metabolism', 'Male', 'Microsomes, Liver', 'Mitochondria, Liver', 'Mitochondrial Swelling', 'NAD', 'Oxygen Consumption', 'Rats', 'Thiobarbiturates', 'Vitamin E'] | 215,851 | [['D02.047.064'], ['B01.050'], ['E05.242.251'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D02.033.375'], ['G03.458'], ['A11.284.835.540.541'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['G04.590'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of aglycosylation on the binding of mouse IgG to staphylococcal protein A. | Aglycosylated IgG produced by hybridoma cells cultured in the presence of tunicamycin was compared with normal IgG for its ability to bind to staphylococcal protein A. No differences were found in binding or elution profiles. It is concluded that aglycosylation does not produce major structural alterations at the CH2-C... | ['Animals', 'Electrophoresis, Polyacrylamide Gel', 'Hybridomas', 'Immunoglobulin G', 'Mice', 'Staphylococcal Protein A', 'Tunicamycin'] | 6,653,789 | [['B01.050'], ['E05.196.401.402', 'E05.301.300.319'], ['A11.251.353.485', 'A11.251.600.485'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.097.820', 'D23.050.161.821'], ['D03.383.742.680.725', 'D13.570.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Views about responsibility for alcohol addiction and negative evaluations of naltrexone. | BACKGROUND: Moral philosophers have debated the extent to which persons are individually responsible for the onset of and recovery from addiction. Empirical investigators have begun to explore counselors' attitudes on these questions. Meanwhile, a separate literature has investigated counselors' negative attitudes towa... | ['Adolescent', 'Adult', 'Alcoholism', 'Attitude of Health Personnel', 'Counseling', 'Data Collection', 'Female', 'Humans', 'Male', 'Middle Aged', 'Naltrexone', 'Narcotic Antagonists', 'Young Adult'] | 25,886,539 | [['M01.060.057'], ['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.100.050', 'N05.300.100'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Influence of Gait Speeds on Contact Forces of Lower Limbs. | While walking with fast speed aims to promote health and fitness of individuals, the potential risk on lower limb joint loading across walking speed is still unknown. In order to determine the joint contact force loading associated with different walking speeds, fifteen young male and fifteen female participants perfor... | ['Adult', 'Biomechanical Phenomena', 'Exercise Test', 'Female', 'Gait', 'Humans', 'Lower Extremity', 'Male', 'Walking Speed', 'Weight-Bearing', 'Young Adult'] | 29,065,630 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610'], ['E01.370.600.250.500', 'G11.427.410.568.900.750.500'], ['G01.374.965'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development and validation of the Sports Athlete Foot and Ankle Score: an instrument for sports-related ankle injuries. | BACKGROUND: Many existing scoring systems assess ankle function, but there is no evidence that any of them has been validated in a group of patients with a higher demand on their ankle function. Problems include ceiling effects, not being able to detect change or they do not contain a sports-subscale. The aim of this s... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Ankle Injuries', 'Ankle Joint', 'Athletes', 'Athletic Injuries', 'Foot', 'Humans', 'Male', 'Surveys and Questionnaires', 'Trauma Severity Indices', 'Young Adult'] | 23,830,163 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['C26.558.100'], ['A02.835.583.378.062'], ['M01.072'], ['C26.115'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Laboratory contamination affecting orthopedic surgical management. | Bacterial contamination of pathology specimens can occur during collection, transport, or laboratory processing. Recognized sources of laboratory contamination include contamination of microscopy slides before use and contamination of reagents. We present 2 cases where contamination of glass beads used in the microbiol... | ['Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Arthroplasty, Replacement, Hip', 'Biopsy', 'Diagnostic Errors', 'Disease Management', 'Equipment Contamination', 'False Positive Reactions', 'Female', 'Gram-Positive Bacteria', 'Gram-Positive Bacterial Infections', 'Hip Joint', 'Hip Prosthesis', 'Hospital Departme... | 21,397,450 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.354', 'N02.421.450.280'], ['N04.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Religiosity and preferences for life-prolonging medical treatments in African-American and white elders: a mediation study. | Research on end-of-life treatment preferences has documented robust racial differences, with African-Americans preferring more life-prolonging treatment than Whites. Although little research has attempted to explain these racial differences systematically, speculation has centered on religiosity. We examined a dimensio... | ['African Americans', 'Aged', 'Aged, 80 and over', 'Attitude to Death', 'Cultural Characteristics', 'Cultural Diversity', 'Depression', 'European Continental Ancestry Group', 'Female', 'Health Behavior', 'Health Status', 'Humans', 'Life Support Care', 'Male', 'Middle Aged', 'Patient Acceptance of Health Care', 'Patient... | 18,300,651 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.125', 'N05.300.125'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['F01.145.126.350'], ['M01.686.508.400'], ['F01.145.488'], ['I01.240.425', 'N01.224.425', 'N06.850.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The indices of EEG spatial synchronization in normal 10- to 12-year-old schoolchildren and in learning difficulties]. | 10-12-year-old schoolchildren were divided into three groups: a normal one, a group with psychological problems, and a third one with medical problems. The EEG was recorded at resting and while reading a text. An obviously higher global spatial synchronisation was found in the normal group as compared with the "medical... | ['Adaptation, Psychological', 'Brain Mapping', 'Cerebral Cortex', 'Child', 'Cortical Synchronization', 'Humans', 'Learning Disabilities', 'Psychophysiology', 'Reading', 'Wakefulness'] | 10,494,586 | [['F01.058'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['M01.060.406'], ['E01.370.376.300.437.500', 'E01.370.405.245.575.500', 'G07.265.256.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.6... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Nightmare Themes: An Online Study of Most Recent Nightmares and Childhood Nightmares. | STUDY OBJECTIVES: Even though the common diagnostic criteria (ICSD-3, DSM-5) acknowledge that nightmares do not only contain anxiety/fear (definition of the ICD-10) but also other emotions such as grief, disgust, and anger, the definition of a nightmare still focuses on threats to survival, security, or physical integr... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Dreams', 'Female', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 29,458,691 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F02.463.188.634.309', 'F02.830.855.268'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses. | OBJECTIVE: Adjuvantation of an H5N1 split-virion influenza vaccine with AS03(A) substantially reduces the antigen dose required to produce a putatively protective humoral response and promotes cross-clade neutralizing responses. We determined the effect of adjuvantation on antibody persistence and B- and T-cell-mediate... | ['Adjuvants, Immunologic', 'Adolescent', 'Adult', 'Amino Acid Sequence', 'Antibodies, Neutralizing', 'Antibodies, Viral', 'B-Lymphocytes', 'CD4-Positive T-Lymphocytes', 'Cross Reactions', 'Disease Outbreaks', 'Female', 'Hemagglutinins', 'Humans', 'Immunity, Cellular', 'Immunity, Humoral', 'Immunologic Memory', 'Influen... | 21,174,144 | [['D27.505.696.477.067'], ['M01.060.057'], ['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.063.438', 'A11.118.6... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Classification, distribution and change of Uighur medicinal materials resources]. | With the development and change of Uygur medicine, The sources,medicinal parts and producing area of some Uygur Medicine have changed. It is more important to master the classification, distribution and change of Uygur medicinal materials. These were more than 1 200 kinds Uygur medicine in history were resaerched by fi... | ['China', 'Europe', 'Plants, Medicinal'] | 29,902,879 | [['Z01.252.474.164'], ['Z01.542'], ['B01.650.560']] | ['Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
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