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Prosthodontic management of an irradiated maxillectomy patient with severe trismus using implant-supported prostheses: a clinical report. | Trismus and limited oral access present a clinical challenge to prosthodontic management. An edentulous patient who developed microstomia after a maxillary tumor resection and radiation therapy is presented. The clinical procedure and the rationale for the treatment approach are discussed. Implanted-supported prosthese... | ['Aged', 'Dental Implants', 'Dental Prosthesis, Implant-Supported', 'Denture Bases', 'Denture Design', 'Denture Retention', 'Denture, Complete', 'Denture, Overlay', 'Humans', 'Male', 'Maxilla', 'Maxillary Sinus Neoplasms', 'Microstomia', 'Osteosarcoma', 'Palatal Obturators', 'Radiotherapy, Intensity-Modulated', 'Trismu... | 18,456,045 | [['M01.060.116.100'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.706', 'E07.695.190.185'], ['E06.780.346.760.281', 'E07.695.190.200.200'], ['E06.780.346.760.300', 'E06.912.250'], ['E06.780.346.760.550'], ['E06.780.346.760.775', 'E07.695.190.200.205'], ['E06.780.346.760.887',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Association Between Immigration Status and Acute Stroke Care: A Retrospective Study. | Background and Purpose- Immigrants to high-income countries have a lower incidence of stroke compared with long-term residents; however, little is known about the care and outcomes of stroke in immigrants. Methods- We used linked clinical and administrative data to conduct a retrospective cohort study of adults seen in... | ['Age Distribution', 'Aged', 'Aged, 80 and over', 'Anticoagulants', 'Antihypertensive Agents', 'Carotid Arteries', 'Cohort Studies', 'Comorbidity', 'Coronary Artery Disease', 'Deglutition Disorders', 'Diabetes Mellitus', 'Echocardiography', 'Electrocardiography, Ambulatory', 'Emigrants and Immigrants', 'Emigration and ... | 32,279,618 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.502.119'], ['D27.505.954.411.162'], ['A07.015.114.186'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C14.280.647.250.260', 'C14... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The role of ultrasonography in the evaluation of abdominal fat: analysis of technical and methodological issues. | RATIONALE AND OBJECTIVES: Ultrasonography (US) is becoming popular for the assessment of adiposity, but no one has studied this tool in the light of its potential limitations. Our purpose was to investigate the impact of technical conditions on the evaluation of abdominal fat by US.MATERIALS AND METHODS: Forty-five hea... | ['Abdominal Fat', 'Algorithms', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Male', 'Middle Aged', 'Observer Variation', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Single-Blind Method', 'Ultrasonography'] | 24,029,060 | [['A10.165.114.830.500'], ['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Aortic stiffness and left ventricular mass in a rat model of isolated systolic hypertension. | We tested whether cardiac mass can be related to decreased aortic stiffness in an original rat model of isolated systolic hypertension. Increased aortic stiffness was produced by calcium overload of elastic arteries after vitamin D3 plus nicotine treatment. Half of the animals were chronically treated with the angioten... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Antihypertensive Agents', 'Aorta', 'Aorta, Thoracic', 'Calcium, Dietary', 'Cholecalciferol', 'Data Interpretation, Statistical', 'Elasticity', 'Hemodynamics', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Indoles', 'Male', 'Nicotine', 'Perindopril', 'Placebos... | 7,490,156 | [['D27.505.519.389.745.085'], ['B01.050'], ['D27.505.954.411.162'], ['A07.015.114.056'], ['A07.015.114.056.372'], ['D01.146.395'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Accurate frozen-density embedding potentials as a first step towards a subsystem description of covalent bonds. | The frozen-density embedding (FDE) scheme [Wesolowski and Warshel, J. Phys. Chem. 97, 8050 (1993)] relies on the use of approximations for the kinetic-energy component v(T)[rho(1),rho(2)] of the embedding potential. While with approximations derived from generalized-gradient approximation kinetic-energy density functio... | ['Ammonia', 'Boranes', 'Dimerization', 'Electrons', 'Ethane', 'Kinetics', 'Models, Chemical', 'Models, Molecular', 'Molecular Conformation', 'Quantum Theory', 'Thermodynamics', 'Water'] | 20,441,252 | [['D01.362.075', 'D01.625.050'], ['D01.132.105', 'D02.203.087'], ['G02.206', 'G03.230'], ['G01.249.335', 'G01.358.500.750'], ['D02.455.326.146.379'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['E05.599.595'], ['G02.111.570.820'], ['H01.671.579.800'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents. | In the year 2010, effluents from 90 European wastewater treatment plants (WWTPs) were analyzed for 156 polar organic chemical contaminants. The analyses were complemented by effect-based monitoring approaches aiming at estrogenicity and dioxin-like toxicity analyzed by in vitro reporter gene bioassays, and yeast and di... | ['Data Collection', 'Diatoms', 'Environmental Monitoring', 'European Union', 'Household Products', 'Organic Chemicals', 'Saccharomyces cerevisiae', 'Toxicity Tests, Acute', 'Waste Disposal, Fluid', 'Waste Water', 'Water Pollutants, Chemical', 'Water Purification'] | 24,091,184 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.750.200'], ['N06.850.460.350.080', 'N06.850.780.375'], ['I01.615.500.475'], ['J01.516'], ['D02'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['E05.940.790'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.93... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Considerations for human exposure standards for fast-rise-time high-peak-power electromagnetic pulses. | Development of new emitter systems capable of producing high-peak-power electromagnetic pulses with very fast rise times and narrow pulse widths is continuing. Such directed energy weapons systems will be used in the future to defeat electronically vulnerable targets. Human exposures to these pulses can be expected dur... | ['Animals', 'Haplorhini', 'Humans', 'Maximum Allowable Concentration', 'Microwaves', 'Radiation Dosage'] | 7,646,411 | [['B01.050'], ['B01.050.150.900.649.313.988.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.210', 'N06.850.460.350.600.615'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250']] | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Investigation of neutron-induced damage in DNA by atomic force microscopy: experimental evidence of clustered DNA lesions. | Using atomic force microscopy (AFM), we have investigated neutron-induced DNA double-strand breaks in plasmids in aqueous solution. AFM permits direct measurement of individual DNA molecules with an accuracy of a few nanometers. Furthermore, the analysis of the DNA fragment size distribution is non-parametric, whereas ... | ['DNA', 'DNA Damage', 'In Vitro Techniques', 'Microscopy, Atomic Force', 'Neutrons', 'Plasmids', 'Relative Biological Effectiveness', 'Solutions', 'Water'] | 9,840,180 | [['D13.444.308'], ['G05.200'], ['E05.481'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['G01.249.660.250'], ['G05.360.600'], ['N06.850.810.250.275'], ['D26.776'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A microRNA signature from serum exosomes of patients with glioma as complementary diagnostic biomarker. | Malignant gliomas, the most frequent primary brain tumors, are characterized by a dismal prognosis. Reliable biomarkers complementary to neuroradiology in the differential diagnosis of gliomas and monitoring for post-surgical progression are unmet needs. Altered expression of several microRNAs in tumour tissues from pa... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Brain Neoplasms', 'Diagnosis, Differential', 'Exosomes', 'Female', 'Glioma', 'Humans', 'Male', 'MicroRNAs', 'Middle Aged', 'Sensitivity and Specificity'] | 29,076,001 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.171'], ['A11.284.295.588.750', 'A11.284.430.214.190.875.190.880.495'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation and identification of Clostridium perfringens in the venom and fangs of Loxosceles intermedia (brown spider): enhancement of the dermonecrotic lesion in loxoscelism. | Loxoscelism or the envenoming by the brown spiders (Loxosceles genus spiders), may produce extensive dermonecrosis and hemorrhage at the bite site and, eventually, systemic reactions that may be lethal. Isolation and identification of many different bacteria, among them Clostridium perfringens, of great medical importa... | ['Animals', 'Clostridium perfringens', 'Necrosis', 'Phosphoric Diester Hydrolases', 'Rabbits', 'Spider Bites', 'Spider Venoms', 'Spiders', 'Tooth'] | 11,738,234 | [['B01.050'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['C23.550.717'], ['D08.811.277.352.640'], ['B01.050.150.900.649.313.968.700'], ['C25.723.127.723', 'C26.176.790'], ['D20.888.065.870', 'D23.946.833.065.870'], ['B01.050.500.131.166.803'], ['A14.549.167.860']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nitric oxide mitigates apoptosis in human endothelial cells induced by 9,10-phenanthrenequinone: role of proteasomal function. | It has been widely recognized that nitric oxide (NO) suppresses oxidative damage of endothelial cell, but little is known about its pathophysiological role in apoptotic induction by 9,10-phenanthrenequinone (9,10-PQ), a major quinone component in diesel exhaust particles. Here, we have investigated the change in NO lev... | ['Apoptosis', 'Blotting, Western', 'Cell Line', 'Cell Survival', 'Endothelial Cells', 'Enzyme Inhibitors', 'Glutathione', 'Guanylate Cyclase', 'Humans', 'Hydrogen Peroxide', 'Mutagens', 'Nitric Oxide', 'Nitric Oxide Donors', 'Nitric Oxide Synthase', 'Oxidative Stress', 'Phenanthrenes', 'Proteasome Endopeptidase Complex... | 20,026,164 | [['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['G04.346'], ['A11.436.275'], ['D27.505.519.389'], ['D12.644.456.448'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High sensitivity troponin: Does the 50% delta change alter clinical outcomes in chest pain presentations to the emergency room? | BACKGROUND: The National Heart Foundation (NHF) and Cardiac Society of Australia and New Zealand (CSANZ) Acute Coronary Syndrome (ACS) guidelines recommend the use of a high sensitivity troponin assay (hsTrop) in the assessment of patients presenting with ACS. A troponin delta of 50% compared with the previously recomm... | ['Australia', 'Biomarkers', 'Chest Pain', 'Coronary Artery Disease', 'Emergency Service, Hospital', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'New Zealand', 'Retrospective Studies', 'Troponin T'] | 25,705,009 | [['Z01.639.100', 'Z01.678.100.373'], ['D23.101'], ['C23.888.592.612.233'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.05... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Structural requirements for CD43 function. | The regulation of T cell activation and adhesion by CD43 (leukosialin, sialophorin) has been thought to be mainly a function of the large size and negative charge of the extracellular domain of the protein. In this work, we demonstrate that the cytoplasmic tail is both necessary and sufficient for the negative regulato... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, CD', 'Cell Adhesion', 'Cell Line', 'Cells, Cultured', 'Cytoplasm', 'Humans', 'Intracellular Fluid', 'Leukosialin', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Mutation', 'Protein Structure, Tertiary', 'Sialoglycoproteins', 'Structure-Activity Relationship'] | 10,201,935 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G04.022'], ['A11.251.210'], ['A11.251'], ['A11.284.430.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.429', 'A11.284.835.450', 'A12.207.515'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA-DR typing and lymphocyte subset evaluation in rheumatic heart disease: a search for immune response factors. | Several autoimmune diseases have been associated with increased frequencies of specific histocompatibility (HLA) antigens, particularly for the D (DR) locus, that may be linked to immune response genes. Rheumatic valvular heart disease (RHD) has been postulated to have autoimmune features, but HLA associations have not... | ['Adolescent', 'Adult', 'Aged', 'Alleles', 'Female', 'HLA-D Antigens', 'HLA-DR Antigens', 'HLA-DR4 Antigen', 'HLA-DR6 Antigen', 'Humans', 'Lymphocytes', 'Male', 'Middle Aged', 'Rheumatic Heart Disease'] | 3,490,780 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['D12.776.395.550.509.400', 'D12.776.543.550.440.400', 'D23.050.301.500.400.400', 'D23.050.301.500.450.400', 'D23.050.705.552.410.400', 'D23.050.705.552.450.400'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Postoperative hypocaloric peripheral parenteral nutrition with branched-chain-enriched amino acids provides no better clinical advantage than fluid management in nonmalnourished colorectal cancer patients. | To assess clinical efficacy of using postoperative branched-chain amino acids (BCAAs)-enriched nutritional support in lower gastrointestinal cancer patients, we conducted a retrospective observational study comparing this regimen with traditional fluid management. Sixty-one eligible colorectal cancer patients consecuti... | ['Aged', 'Alanine Transaminase', 'Amino Acids, Branched-Chain', 'Bilirubin', 'Blood Glucose', 'Colorectal Neoplasms', 'Dietary Fats', 'Dietary Proteins', 'Energy Intake', 'Female', 'Glucose', 'Humans', 'Lymphocytes', 'Male', 'Middle Aged', 'Parenteral Nutrition', 'Postoperative Period', 'Recommended Dietary Allowances'... | 25,298,128 | [['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D12.125.070'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['D09.947.875.359.448.500'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Six months of balloon treatment does not predict the success of gastric banding. | BACKGROUND: We studied whether weight loss by intragastric balloon would predict the outcome of subsequent gastric banding with regard to weight loss and BMI reduction.METHODS: A prospective cohort of patients with a body mass index (BMI)>40 kg/m(2) received an intragastric balloon for 6 months followed by laparoscopic... | ['Adult', 'Body Mass Index', 'Female', 'Follow-Up Studies', 'Gastric Balloon', 'Gastroplasty', 'Humans', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Patient Selection', 'Predictive Value of Tests', 'Prospective Studies', 'Treatment Outcome', 'Weight Loss'] | 17,355,774 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.430'], ['E02.650.500.062.750', 'E04.062.750', 'E04.210.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ten years on: increased metal ion levels in a cohort of patients who underwent uncemented metal-on-polyethylene total hip arthroplasty. | AIMS: We have previously demonstrated raised cobalt and chromium levels in patients with larger diameter femoral heads, following metal-on-polyethylene uncemented total hip arthroplasty. Further data have been collected, to see whether these associations have altered with time and to determine the long-term implication... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Chromium', 'Cobalt', 'Female', 'Hip Prosthesis', 'Humans', 'Ions', 'Male', 'Middle Aged', 'Polyethylene', 'Prosthesis Design'] | 32,600,130 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Interferon inhibits preferentially the synthesis of proteins associated with growth stimulation of Swiss 3T3 mouse fibroblasts. | The putative role of inhibition of protein synthesis within the antiproliferative effect of interferon was analyzed in serum-stimulated Swiss 3T3 mouse fibroblasts. We observed an apparent coupling between protein-synthesis inhibition during G1 and a delayed entry into the S-phase. To reveal any specificity in the prot... | ['Animals', 'Blood', 'Cell Division', 'Cell Line', 'DNA', 'Dichlororibofuranosylbenzimidazole', 'Fibroblasts', 'Interferon Type I', 'Interphase', 'Mice', 'Protein Biosynthesis', 'RNA, Messenger', 'Transcription, Genetic'] | 3,567,200 | [['B01.050'], ['A12.207.152', 'A15.145'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D13.444.308'], ['D13.570.800.330'], ['A11.329.228'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['G04.144.500'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
One Field Epidemiologist per 200,000 Population: Lessons Learned from Implementing a Global Public Health Workforce Target. | The World Health Organization monitoring and evaluation framework for the International Health Regulations (IHR, 2005) describes the targets for the Joint External Evaluation (JEE) indicators. For workforce development, the JEE defines the optimal target for attaining and complying with the IHR (2005) as 1 trained fiel... | ['Disease Outbreaks', 'Epidemiological Monitoring', 'Epidemiologists', 'Global Health', 'Health Workforce', 'Humans', 'International Health Regulations', 'Public Health Administration'] | 32,004,135 | [['N06.850.290'], ['E05.318.375', 'N06.850.520.460'], ['M01.526.485.353', 'N02.360.345'], ['H02.403.371', 'N01.400.337'], ['N02.350', 'N04.452.525.500', 'N05.300.420.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.655.500.608.400.468', 'N03.706.615.473.250'], ['N04.452.794']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Increased behavioral and neuronal sensitivity to sex pheromone after brief odor experience in a moth. | Plasticity in the response to stimuli related to food and oviposition cues is well documented in insects. However, responses to cues related to reproduction, for example, sex pheromones, are considered to be innate and thus not affected by experience. Here we show that brief preexposure to sex pheromones, without ensui... | ['Animals', 'Behavior, Animal', 'Male', 'Neurons', 'Odorants', 'Sensory Thresholds', 'Sex Attractants', 'Smell', 'Spodoptera'] | 17,510,089 | [['B01.050'], ['F01.145.113'], ['A08.675', 'A11.671'], ['G16.500.275.640', 'N06.230.480'], ['F02.463.593.710'], ['D23.641.800'], ['F02.830.816.643', 'G11.561.790.643'], ['B01.050.500.131.617.720.500.500.937.650.700']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Development of one step RT-PCR technique for detection of H7 subtype avian influenza]. | According to 45 hemagglutinin (HA) gene sequences of H7 subtype of avian influenza virus (AIV), a pair of specific oligonucleotide primers was designed. We developed one step RT-PCR for detecting AIV subtype H7. Sensitivity to detection of allantoic fluid by one step RT-PCR reached 10(5.5) EID50/mL and detection of swa... | ['Animals', 'Birds', 'Chick Embryo', 'Hemagglutinin Glycoproteins, Influenza Virus', 'Influenza A Virus, H7N1 Subtype', 'Influenza in Birds', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity'] | 20,222,464 | [['B01.050'], ['B01.050.150.900.248'], ['A13.350.150', 'A16.331.200'], ['D12.776.964.970.880.345.500'], ['B04.820.480.968.405.400.690'], ['C01.925.782.620.300', 'C22.131.450'], ['E05.393.620.500.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800',... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Supercritical CO2-assisted embossing for studying cell behaviour on microtextured surfaces. | Recently, cell responses to micro- and nanoscale structures have attracted much attention. Although interesting phenomena have been observed, we have encountered some difficulties in elucidating purely topographical effects on cell behaviour. These problems are partially attributable to the introduction of functional g... | ['Biocompatible Materials', 'Carbon Dioxide', 'Cell Adhesion', 'Cell Culture Techniques', 'Humans', 'Mesenchymal Stem Cells', 'Polycarboxylate Cement', 'Surface Properties'] | 18,793,798 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G04.022'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['D25.339.291.700', 'J01.637.051.339.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Biotransformation of (-)-a-pinene by Botrytis cinerea. | (-)-alpha-Pinene (1), a major constituent of many aromatic plants was biotransformed by the plant pathogenic fungus, Botrytis cinerea to afford three new metabolites, characterized as 3beta-hydroxy-(-)-beta-pinene (10%) (3), 9-hydroxy-(-)-a-pinene (12%) (4), 4beta-hydroxy-(-)-alpha-pinene-6-one (16%) (5) by physical an... | ['Bicyclic Monoterpenes', 'Biotransformation', 'Botrytis', 'Carbon Isotopes', 'Hydrogen', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Monoterpenes', 'Terpenes'] | 12,064,731 | [['D02.455.426.100.080.050', 'D02.455.849.575.141'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['B01.300.381.128'], ['D01.268.150.075', 'D01.496.123'], ['D01.268.406', 'D01.362.340'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D02.455.849.575'], ['D02.455.849']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Norm- and hypo-fractionated radiotherapy is capable of activating human dendritic cells. | Despite the transient immunosuppressive properties of local radiotherapy (RT), this classical treatment modality of solid tumors is capable of inducing immunostimulatory forms of tumor-cell death. The resulting 'immunotoxicity' in the tumor, but not in healthy tissues, may finally lead to immune-mediated destruction of... | ['Antigens, CD', 'Antineoplastic Protocols', 'CD4-Positive T-Lymphocytes', 'Cell Death', 'Cell Differentiation', 'Cell Line, Tumor', 'Colorectal Neoplasms', 'Cytokines', 'Dendritic Cells', 'Dose Fractionation, Radiation', 'Humans', 'Lymphocyte Activation', 'Paracrine Communication'] | 24,512,329 | [['D23.050.301.264.035', 'D23.101.100.110'], ['E02.183.750', 'E02.319.077', 'N05.715.360.330.125.500'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.146'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stratification approach for 3-D euclidean reconstruction of nonrigid objects from uncalibrated image sequences. | This paper addresses the problem of 3-D reconstruction of nonrigid objects from uncalibrated image sequences. Under the assumption of affine camera and that the nonrigid object is composed of a rigid part and a deformation part, we propose a stratification approach to recover the structure of nonrigid objects by first ... | ['Algorithms', 'Artificial Intelligence', 'Calibration', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Subtraction Technique'] | 18,270,085 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['E05.978.155'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['L01.399.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Health care indicators. | Contained in this regular feature of the journal is a section on each of the following five topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; hospital skill mix changes: 1980s; and national economic indicators. | ['Actuarial Analysis', 'Economics', 'Economics, Hospital', 'Health Expenditures', 'Hospitals, Community', 'Prospective Payment System', 'Salaries and Fringe Benefits', 'United States'] | 10,113,563 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['I01.261', 'N03.219'], ['N03.219.262'], ['N03.219.151.450', 'N05.300.385'], ['N02.278.421.306'], ['N03.219.521.710.305.200'], ['N01.824.417.700', 'N04.452.677.800'], ['Z01.107.567.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Involvement of guanylate cyclase and potassium channels on the delayed phase of mouse carrageenan-induced paw oedema. | Previous studies from this laboratory have shown that administration of nitric oxide (NO) donors reduces the early phase (which peaks at 4 h) of carrageenan-induced paw oedema. The aim of this study was to investigate the influence of NO donors on the delayed phase of the mouse paw oedema, which peaks 48 h after carrag... | ['Animals', 'Carrageenan', 'Edema', 'Female', 'Forelimb', 'Guanylate Cyclase', 'Mice', 'Potassium Channels', 'Time Factors'] | 15,464,080 | [['B01.050'], ['D09.698.152'], ['C23.888.277'], ['A13.395'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.157.530.400.600', 'D12.776.543.550.450.750', 'D12.776.543.585.400.750'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conservative Management of Central Cemento-Ossifying Fibroma. | Central cemento-ossifying fibroma is characterized by the combined production of osteoid and cementoid tissue. Radiographically, this lesion is presented as an outlined cortical and variable radiopaque spots, also can be present complete radiolucent or different degrees of radiopacity. The recommended treatment is cure... | ['Conservative Treatment', 'Female', 'Fibroma, Ossifying', 'Humans', 'Mandibular Neoplasms', 'Middle Aged'] | 27,831,973 | [['E02.197'], ['C04.557.450.565.575.400', 'C04.557.450.565.590.340.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.149.721.450.583', 'C05.116.231.754.450.583', 'C05.500.499.583', 'C05.500.607.442', 'C07.320.515.583', 'C07.320.610.583'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Multiple Regression Approach to Normalization of Spatiotemporal Gait Features. | Normalization of gait data is performed to reduce the effects of intersubject variations due to physical characteristics. This study reports a multiple regression normalization approach for spatiotemporal gait data that takes into account intersubject variations in self-selected walking speed and physical properties in... | ['Adolescent', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Child', 'Child, Preschool', 'Data Interpretation, Statistical', 'Female', 'Gait', 'Gait Disorders, Neurologic', 'Humans', 'Machine Learning', 'Male', 'Middle Aged', 'Parkinson Disease', 'Pattern Recognition, Automated', 'Physical Examination', 'Regression Analy... | 26,426,798 | [['M01.060.057'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['M01.060.406'], ['M01.060.406.448'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C10.597.404', 'C23.888.592.413'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Isolated acute funisitis in the absence of acute chorioamnionitis: What does it mean? | OBJECTIVE: Acute funisitis (AF) is most commonly associated with acute chorioamnionitis (AC) and ascending infection. The significance of cases of AF without associated AC or isolated funisitis (IF) is unknown. Our objective was to evaluate clinical and pathologic features of IF and to determine its significance.STUDY ... | ['Chorioamnionitis', 'Female', 'Humans', 'Meconium', 'Placenta', 'Pregnancy', 'Retrospective Studies'] | 30,712,665 | [['C13.703.277.030', 'C13.703.420.339.260', 'C13.703.590.268', 'C16.300.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.459.529', 'A16.378.529'], ['A16.710'], ['G08.686.784.769'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A nucleoporin is required for induction of Ca2+ spiking in legume nodule development and essential for rhizobial and fungal symbiosis. | Nuclear-cytoplasmic partitioning and traffic between cytoplasmic and nuclear compartments are fundamental processes in eukaryotic cells. Nuclear pore complexes mediate transport of proteins, RNAs and ribonucleoprotein particles in and out of the nucleus. Here we present positional cloning of a plant nucleoporin gene, N... | ['Alleles', 'Amino Acid Sequence', 'Calcium', 'Calcium Signaling', 'Cations, Divalent', 'Cell Nucleus', 'Cloning, Molecular', 'Fabaceae', 'Gene Expression Regulation, Plant', 'Molecular Sequence Data', 'Mycorrhizae', 'Nuclear Pore Complex Proteins', 'Phenotype', 'Plant Proteins', 'Rhizobium', 'Sequence Alignment', 'Sym... | 16,407,163 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D01.248.497.300.333'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.393.220'], ['B01.650.940.800.575.912.250.401'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Maternal Infant Microbiome: Considerations for Labor and Birth. | The human microbiome plays a role in maintaining health, but is also thought to attenuate and exacerbate risk factors for adverse maternal-child health outcomes. The development of the microbiome begins in utero; however, factors related to the labor and birth environment have been shown to influence the initial coloni... | ['Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Cesarean Section', 'Female', 'Gastrointestinal Microbiome', 'Humans', 'Infant, Newborn', 'Maternal-Fetal Exchange', 'Mothers', 'Parturition', 'Pregnancy'] | 28,825,919 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['E04.520.252.500'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769.455'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Prevalence of Campylobacter jejuni, Campylobacter lari, and Campylobacter coli in different ecological guilds and taxa of migrating birds. | A total of 1,794 migrating birds trapped at a coastal site in southern Sweden were sampled for detection of Campylobacter spp. All isolates phenotypically identified as Campylobacter jejuni and a subset of those identified as non-C. jejuni were identified to the species level by PCR-based techniques. C. jejuni was foun... | ['Animals', 'Birds', 'Campylobacter', 'Campylobacter coli', 'Campylobacter jejuni', 'Disease Reservoirs', 'Ecology', 'Emigration and Immigration', 'Prevalence'] | 12,450,810 | [['B01.050'], ['B01.050.150.900.248'], ['B03.440.180', 'B03.660.150.235.250.500'], ['B03.440.180.200', 'B03.660.150.235.250.500.100'], ['B03.440.180.425', 'B03.660.150.235.250.500.375'], ['N06.850.520.203.250'], ['H01.158.273.248', 'H01.277.249'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.... | ['Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson's disease by increasing expression of BNDF. | The incretins glucagon-like peptide 1 (GLP-1) and glucose dependent insulinotropic polypeptide (GIP) are growth factors with neuroprotective properties. GLP-1 mimetics are on the market as treatments for type 2 diabetes and are well tolerated. Both GLP-1 and GIP mimetics have shown neuroprotective properties in animal ... | ['Animals', 'Apoptosis', 'Brain-Derived Neurotrophic Factor', 'Corpus Striatum', 'Disease Models, Animal', 'Glucagon-Like Peptide-1 Receptor', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Motor Activity', 'Muscle Strength', 'Neurons', 'Neuroprotective Agents', 'Parkinsonian Disorders', 'Proto-Oncogene Proteins c-akt', 'Recep... | 26,453,833 | [['B01.050'], ['G04.146.954.035'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A08.186.211.200.885.287.249.487'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.543.750.695.021.500', 'D12.776.543.750.750.360.100.500'], ['B01.050.150.900.649.313.992.635.505.500']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling. | We have shown that cutaneous cooling-sensitive receptors can work as thermostats of skin temperature against cooling. However, molecule of the thermostat is not known. Here, we studied whether cooling-sensitive TRPM8 channels act as thermostats. TRPM8 in HEK293 cells generated output (y) when temperature (T) was below ... | ['Adipose Tissue, Brown', 'Animals', 'Autonomic Nervous System', 'Behavior, Animal', 'Body Temperature Regulation', 'Cold Temperature', 'HEK293 Cells', 'Humans', 'Mice', 'Skin Temperature', 'TRPM Cation Channels'] | 21,407,809 | [['A10.165.114.322'], ['B01.050'], ['A08.800.050'], ['F01.145.113'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.3... | ['Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Phosphatidylcholine-specific phospholipase C but not gamma interferon regulate gene expression and secretion of CC Chemokine Ligand-2 (CCL-2) by human astrocytes during infection by Toxoplasma gondii. | We have used human astrocytoma-derived cells to investigate the cellular responses of central nervous system cells to Toxoplasma gondii infection. At 24 h post inoculation, the secretion of CCL-2 (or Monocyte Chemotactic Protein-1) was augmented six-fold over the control. This secretion was down-regulated by D609, a sp... | ['Animals', 'Astrocytes', 'Bridged-Ring Compounds', 'Cell Line, Tumor', 'Chemokine CCL2', 'Enzyme Inhibitors', 'Gene Expression Regulation', 'Humans', 'Interferon-gamma', 'Norbornanes', 'RNA, Messenger', 'Thiocarbamates', 'Thiones', 'Toxoplasma', 'Toxoplasmosis', 'Type C Phospholipases'] | 15,752,119 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['D02.455.426.100', 'D04.075'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D27.505.519.389'], ['G05.308'], ['B01.050.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of pellicle growth morphological characteristics and clinical presentation of Mycobacterium tuberculosis isolates. | Trehalose 6,6'dimycolate (TDM) is a glycolipid found in nearly pure form on the surface of virulent Mycobacterium tuberculosis (MTB). This manuscript investigated the production of TDM, growth rate and colony morphology of multiple strains of MTB, each of which had been isolated from both pulmonary (sputum) and extrapu... | ['Biopsy', 'Cord Factors', 'Granuloma', 'Humans', 'Mycobacterium tuberculosis', 'Sputum', 'Time Factors', 'Tuberculosis, Pulmonary', 'Virulence'] | 27,742,461 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D10.390.240', 'D23.946.123.208'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Several environmental oestrogens are also anti-androgens. | There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals that mimic hormones, in particular sex steroids. It has been hypothesised that exposure to such chemicals may be responsible for adverse effects in both humans and wildlife. Until now, chemical... | ['Androgen Antagonists', 'Androgens', 'Benzhydryl Compounds', 'Biological Assay', 'DDT', 'Dichlorodiphenyl Dichloroethylene', 'Diethylstilbestrol', 'Environmental Pollution', 'Estrogen Antagonists', 'Estrogens', 'Flutamide', 'Fungicides, Industrial', 'Gene Expression', 'Hormones', 'Humans', 'Oxazoles', 'Pesticides', 'P... | 9,846,162 | [['D06.347.065', 'D27.505.696.399.450.065'], ['D27.505.696.399.472.161'], ['D02.455.426.559.389.115'], ['E05.091'], ['D02.455.526.439.255'], ['D02.455.526.439.292'], ['D02.455.426.559.389.150.700.725.500'], ['N06.850.460'], ['D06.347.295', 'D27.505.696.399.450.327'], ['D27.505.696.399.472.277'], ['D02.065.199.420', 'D0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Correlates of tumor development in patients with myotonic dystrophy. | Patients with myotonic dystrophy (DM) have recently been reported to be at increased risk of tumor development, but clinical associations related to this observation are unknown. We calculated the odds ratios (ORs) and 95 % confidence intervals (CI) of self-reported tumor development by patients' demographic and clinic... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Myotonic Dystrophy', 'Neoplasms', 'Risk Factors', 'Sex Factors', 'Young Adult'] | 22,619,053 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.52... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Laboratory and On-field Data Collected by a Head Impact Monitoring Mouthguard. | Although concussion continues to be a major source of acute and chronic injury in automotive, athletic and military arenas, concussion injury mechanisms and risk functions are ill-defined. This lack of definition has hindered efforts to develop standardized concussion monitoring, safety testing and protective counterme... | ['Adolescent', 'Athletic Injuries', 'Boxing', 'Brain Concussion', 'Child', 'Football', 'Head Protective Devices', 'Humans', 'Mouth Protectors', 'Young Adult'] | 31,946,308 | [['M01.060.057'], ['C26.115'], ['I03.450.642.845.210'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['M01.060.406'], ['I03.450.642.845.300'], ['E07.700.380', 'J01.637.708.560.750'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
Isolation and characterization of two cyclin-like cDNAs from Arabidopsis. | Cyclins are key regulators of a family of protein kinases called cyclin-dependent kinases (Cdks). Specific cyclins interact with specific Cdks to regulate the different transition points in the cell cycle. Six mitotic-like cyclins have previously been reported in Arabidopsis thaliana. Using polymerase chain reaction am... | ['Amino Acid Sequence', 'Arabidopsis', 'Base Sequence', 'Conserved Sequence', 'Cyclin B', 'Cyclin B1', 'DNA, Complementary', 'Evolution, Molecular', 'Molecular Sequence Data', 'Phylogeny', 'Sequence Alignment', 'Sequence Homology, Amino Acid'] | 9,484,485 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580'], ['D12.644.360.262.120', 'D12.776.167.218.120', 'D12.776.476.262.120'], ['D12.644.360.262.120.100', 'D12.776.167.218.120.100', 'D12.776.476.262.120.100'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Integrating docking and molecular dynamics approaches for a series of proline-based 2,5-diketopiperazines as novel áâ-tubulin inhibitors. | In this work, docking tools were utilized in order to study the binding properties of more than five hundred of proline-based 2,5-diketopiperazine in the binding site of áâ-tubulin. Results revealed that 20 compounds among them showed lower binding energies in comparison with Tryprostatin-A, a well known tubulin inhibi... | ['Amino Acid Motifs', 'Binding Sites', 'Diketopiperazines', 'Humans', 'Hydrogen Bonding', 'Indole Alkaloids', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Molecular Sequence Data', 'Piperazines', 'Proline', 'Protein Binding', 'Protein Folding', 'Protein Structure, Secondary', 'Protein Structure, Te... | 25,616,934 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.120'], ['D03.383.606.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['D03.132.436', 'D03.633.100.473.402', 'D03.633.100.496.500.500'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.599.595.500', 'G02.111.570.895', 'L01.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Causes and significance of markedly elevated serum ferritin levels in an academic medical center. | OBJECTIVE: A markedly elevated serum ferritin level has been associated with inflammatory conditions such as adult-onset Still's disease, systemic juvenile idiopathic arthritis, and hemophagocytic lymphohistiocytosis/macrophage activation syndrome. Hyperferritinemia, however, can also be caused by a wide variety of dis... | ['Academic Medical Centers', 'Adolescent', 'Adult', 'African Continental Ancestry Group', 'Aged', 'Aged, 80 and over', 'Arthritis, Juvenile', 'Asian Americans', 'European Continental Ancestry Group', 'Female', 'Ferritins', 'Hispanic Americans', 'Humans', 'Iron Overload', 'Lymphohistiocytosis, Hemophagocytic', 'Male', '... | 23,965,472 | [['N02.278.020'], ['M01.060.057'], ['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.686.508.200.100', 'M01.686.754.225'], ['M01.686.508.400'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['M01.686.754.441'... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Locking and unlocking of ribosomal motions. | During the ribosomal translocation, the binding of elongation factor G (EF-G) to the pretranslocational ribosome leads to a ratchet-like rotation of the 30S subunit relative to the 50S subunit in the direction of the mRNA movement. By means of cryo-electron microscopy we observe that this rotation is accompanied by a 2... | ['Binding Sites', 'Cryoelectron Microscopy', 'Eukaryotic Cells', 'Models, Molecular', 'Molecular Conformation', 'Peptide Elongation Factor G', 'Peptides', 'Protein Biosynthesis', 'Protein Structure, Tertiary', 'Protein Subunits', 'RNA, Messenger', 'RNA, Transfer', 'Ribosomes', 'Rotation'] | 12,859,903 | [['G02.111.570.120'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['A11.450'], ['E05.599.595'], ['G02.111.570.820'], ['D08.811.277.040.330.300.100.200', 'D12.776.157.325.150.200', 'D12.776.835.700.350.200'], ['D12.644'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['G02.111.570.820.709.610'], ['D12.776.813']... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nasal glioma. | Nasal gliomas are uncommon congenital lesions arising from abnormal embryonic development. Clinically, these masses are firm and incompressible. Histologically, they are made up of astrocytes and neuroglial cells, embedded in fibrous and vascular connective tissue. Proper management of a nasal glioma requires a multidi... | ['Glioma', 'Humans', 'Infant', 'Male', 'Nose Neoplasms'] | 17,148,805 | [['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.588.149.721.600', 'C04.588.443.665.650', 'C05.116.231.754.600', 'C08.460.669', 'C08.785.600', 'C09.603.669', 'C09.647.685']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Finite element analysis of the lumbar spine with a new cage using a topology optimization method. | In recent years, degenerative spinal instability has been effectively treated with a cage. However, little attention is focused on the design concept of the cage. The purpose of this study was to develop a new cage and evaluate its biomechanical function using a finite element method (FEM). This study employed topology... | ['Biomechanical Phenomena', 'Computational Biology', 'Equipment Design', 'Finite Element Analysis', 'Humans', 'Internal Fixators', 'Lumbar Vertebrae', 'Models, Biological', 'Range of Motion, Articular', 'Software', 'Spine', 'Stress, Mechanical'] | 16,426,979 | [['G01.154.090', 'G01.374.089'], ['H01.158.273.180', 'L01.313.124'], ['E05.320'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.370', 'E07.858.442.660.460', 'E07.858.690.725.460'], ['A02.835.232.834.519'], ['E05.599.395'], ['E01.370.600.700', 'G11.427.760'], ['L01.224.900'], ['A02.835.232.834'... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-Term Effect of Serial Infections with H13 and H16 Low-Pathogenic Avian Influenza Viruses in Black-Headed Gulls. | UNLABELLED: Infections of domestic and wild birds with low-pathogenic avian influenza viruses (LPAIVs) have been associated with protective immunity to subsequent infection. However, the degree and duration of immunity in wild birds from previous LPAIV infection, by the same or a different subtype, are poorly understoo... | ['Age Factors', 'Animals', 'Antibodies, Viral', 'Charadriiformes', 'Cross Protection', 'Disease Resistance', 'Disease Susceptibility', 'Hemagglutinins, Viral', 'Host Specificity', 'Immunity, Humoral', 'Immunization', 'Influenza A virus', 'Influenza in Birds', 'Molecular Sequence Data', 'Recurrence', 'Virus Shedding'] | 26,339,062 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.248.150'], ['G12.450.275'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['C23.550.291.687', 'G07.100.250'], ['D12.776.964.9... | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Are k13 and plasmepsin II genes, involved in Plasmodium falciparum resistance to artemisinin derivatives and piperaquine in Southeast Asia, reliable to monitor resistance surveillance in Africa? | Mutations in the propeller domain of Plasmodium falciparum kelch 13 (Pfk13) gene are associated with artemisinin resistance in Southeast Asia. Artemisinin resistance is defined by increased ring survival rate and delayed parasite clearance half-life in patients. Additionally, an amplification of the Plasmodium falcipar... | ['Africa', 'Antimalarials', 'Artemisinins', 'Aspartic Acid Endopeptidases', 'Drug Resistance', 'Humans', 'Malaria, Falciparum', 'Plasmodium falciparum', 'Protozoan Proteins', 'Quinolines'] | 31,443,646 | [['Z01.058'], ['D27.505.954.122.250.100.085'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530.650', 'C... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Sepsis-induced lung inflammation is modulated by insulin. | BACKGROUND: We have previously shown that diabetic rats are more susceptible to sepsis, but that the Acute lung injury (ALI) secondary to sepsis is less intense than in non-diabetics. In the present study, we further investigated the ALI-secondary to sepsis in diabetic rats and the effect of insulin treatment.METHODS: ... | ['Actins', 'Acute Lung Injury', 'Alloxan', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Cell Count', 'Diabetes Mellitus, Experimental', 'Dinoprostone', 'Edema', 'Insulin', 'Leukocytes', 'Male', 'Myofibroblasts', 'Pneumonia', 'Rats', 'Rats, Wistar', 'Sepsis', 'Specific Pathogen-Free Organisms', 'Transforming Growth Facto... | 25,398,720 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['C08.381.520.500'], ['D03.383.742.698.122'], ['B01.050'], ['E05.927.100.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D10.251.355.255.550.250.200', 'D23.46... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of a biphasic desogestrel-containing oral contraceptive on carbohydrate metabolism and various hormonal parameters. | During 6 cycles of treatment of 19 women, the effect of a low-dose biphasic oral contraceptive containing 40 micrograms ethinylestradiol + 25 micrograms desogestrel (7 tablets) and 30 micrograms ethinylestradiol + 125 micrograms desogestrel (15 tablets) on various hormonal parameters and glucose metabolism was compared... | ['Adult', 'Blood Glucose', 'Carbohydrates', 'Contraceptives, Oral, Combined', 'Contraceptives, Oral, Sequential', 'Dehydroepiandrosterone', 'Dehydroepiandrosterone Sulfate', 'Desogestrel', 'Ethinyl Estradiol', 'Female', 'Gonadal Steroid Hormones', 'Humans', 'Hydrocortisone', 'Insulin', 'Prolactin', 'Sex Hormone-Binding... | 8,436,002 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['D09'], ['D26.310.360', 'D27.505.696.875.360.276.210.100', 'D27.505.954.705.360.276.210.100'], ['D27.505.696.875.360.276.210.400', 'D27.505.954.705.360.276.210.400'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.95... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys. | In mammals, the development of pluripotency and specification of primordial germ cells (PGCs) have been studied predominantly using mice as a model organism. However, divergences among mammalian species for such processes have begun to be recognized. Between humans and mice, pre-implantation development appears relativ... | ['Animals', 'Embryonic Stem Cells', 'Gene Expression Regulation, Developmental', 'Macaca fascicularis', 'Single-Cell Analysis', 'Transcriptome'] | 28,649,393 | [['B01.050'], ['A11.872.700.250'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['E05.242.900'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alpha thalassaemia and the haematology of normal Jamaican children. | Haematological indices were studied from birth to 9 years in a representative sample of 195 children with a normal haemoglobin (AA) genotype subdivided according to the number of alpha globin genes. These were 5 homozygotes for alpha-thalassaemia 2 (two-gene group), 60 heterozygotes for alpha-thalassaemia 2 (three-gene... | ['Child', 'Child, Preschool', 'Female', 'Fetal Hemoglobin', 'Genotype', 'Globins', 'Hemoglobin A2', 'Heterozygote', 'Homozygote', 'Humans', 'Infant', 'Jamaica', 'Male', 'Thalassemia'] | 2,420,505 | [['M01.060.406'], ['M01.060.406.448'], ['D12.776.124.400.303', 'D12.776.422.316.762.320'], ['G05.380'], ['D12.776.422.316'], ['D12.776.124.400.405.450', 'D12.776.422.316.762.380.450'], ['G05.380.383'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.107.084.900.525', 'Z01.639.88... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Temporomandibular disorders in German and Chinese adolescents. | OBJECTIVE: The etiology of temporomandibular disorders (TMD) remains unclear. The aim of this study was, by comparing the prevalence of TMD between adolescents of different ethnic origin, to examine whether certain genetic factors may play a role in causing TMD.SUBJECTS AND METHODS: We assessed the prevalence of TMD ac... | ['Adolescent', 'China', 'Female', 'Genetic Predisposition to Disease', 'Germany', 'Humans', 'Male', 'Prevalence', 'Risk Assessment', 'Risk Factors', 'Temporomandibular Joint Disorders'] | 20,503,001 | [['M01.060.057'], ['Z01.252.474.164'], ['C23.550.291.687.500', 'G05.380.355'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.7... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Coronary flow obstruction in percutaneous aortic valve replacement using self-expandable valved stent: an in vitro study]. | OBJECTIVE: To study the effects of self-expandable and orthotopically implanted percutaneous aortic valved stent on coronary artery flow in vitro.METHODS: Self-expandable valved stent was developed with nitinol stent and bovine pericardium. The ascending aorta of Chinese mini swine hearts was cut proximal to the brachi... | ['Animals', 'Aortic Valve', 'Coronary Circulation', 'Coronary Occlusion', 'Coronary Vessels', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'In Vitro Techniques', 'Stents', 'Swine', 'Swine, Miniature'] | 19,671,342 | [['B01.050'], ['A07.541.510.110'], ['G09.330.100.324'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['A07.015.114.269', 'A07.015.908.194'], ['E07.695.310'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['E05.481'], ['E07.695.750'], ['B01.050.150.900.649.313.500.880'], ['B01.050.150.900.649.313.500.880.399... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clonality and life cycles of intestinal crypts explained by a state dependent stochastic model of epithelial stem cell organization. | The organization and control of stem cells is a key issue in epithelial cell biology. The small intestinal murine crypt is a useful tissue to study such problems since stem cells are known to be located at specific positions at the bottom of the crypt where they are self maintaining. Recent data suggest, that (1) the n... | ['Animals', 'Cell Cycle', 'Clone Cells', 'Epithelial Cells', 'Homeostasis', 'Intestines', 'Mice', 'Models, Biological', 'Stem Cells'] | 9,176,636 | [['B01.050'], ['G04.144'], ['A11.251.353'], ['A11.436'], ['G07.410'], ['A03.556.124'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['A11.872']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppressors of RNA silencing encoded by tomato leaf curl betasatellites. | Virus encoded RNA-silencing suppressors (RSSs) are the key components evolved by the viruses to counter RNA-silencing defense of plants. Whitefly-transmitted begomoviruses infecting tomato crop code for five different proteins, ORF AC4, ORF AC2 and ORF AV2 in DNA-A component, ORF BV1 in DNA-B and ORF beta C1 in satelli... | ['Agrobacterium tumefaciens', 'Animals', 'Begomovirus', 'DNA, Satellite', 'DNA, Viral', 'Genes, Reporter', 'Genes, Suppressor', 'Genetic Vectors', 'Green Fluorescent Proteins', 'Hemiptera', 'Lycopersicon esculentum', 'Plant Diseases', 'Plant Leaves', 'RNA Interference', 'RNA, Small Interfering', 'Tobacco'] | 23,385,812 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['B01.050'], ['B04.280.350.100', 'B04.715.270.100'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['D13.444.308.568'], ['G05.360.340.024.340.435'], ['G05.360.340.024.340.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists. | X-ray structures of the GluR2 ligand-binding core in complex with (S)-Des-Me-AMPA and in the presence and absence of zinc ions have been determined. (S)-Des-Me-AMPA, which is devoid of a substituent in the 5-position of the isoxazolol ring, only has limited interactions with the partly hydrophobic pocket of the ligand-... | ['Animals', 'Binding Sites', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Hydrophobic and Hydrophilic Interactions', 'Isoxazoles', 'Ligands', 'Macromolecular Substances', 'Methionine', 'Models, Molecular', 'Peptides', 'Protein Binding', 'Receptors, AMPA', 'Sulfates', 'Zinc', 'alpha-Amino-3-hydroxy-5-methyl-4-isoxazol... | 12,417,307 | [['B01.050'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['G02.282'], ['G02.409'], ['D03.383.129.385'], ['D27.720.470.480'], ['D05'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['E05.599.595'], ['D12.644'], ['G02.111.679', 'G03.808'], ['D12.776.157.530.400.400.500.100', 'D12.776.54... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Recording and reducing coercive measures in psychiatric hospitals]. | OBJECTIVE: A project of quality management funded by the German Ministry of Health is presented which aims at recording and reducing of coercive measures (seclusion, restraint, forced medication).METHOD: Since 1997, a study group for prevention of violence and coercion consisting of physicians, nurses and other psychia... | ['Coercion', 'Germany', 'Hospitals, Psychiatric', 'Humans', 'Patient Isolation', 'Psychotropic Drugs', 'Restraint, Physical', 'Total Quality Management', 'Violence'] | 15,570,489 | [['I01.880.604.316', 'I01.880.630.200'], ['Z01.542.315'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.770', 'N06.850.780.200.450.650'], ['D27.505.954.427.700'], ['E02.085.700', 'E05.472.760'], ['N04.452.955', 'N04.761.700.675', 'N05.700.792'], ['I01.198.240.856', 'I01.880.735.900']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Selection of subpopulations resistnat to amikacin and netilmicin of gentamicin-resistant clinical strains of Staphylococcus aureus and Staphylococcus epidermidis. | Recently we have found several strains of Staphylococcus aureus and Staphylococcus epidermidis, which in spite of containing aminoglycoside-modifying enzymes (AMEs) remained susceptible to antibiotics such as netilmicin (NET) and amikacin (AN). Assuming an interest in this agent from a clinical point of view, the aim o... | ['Amikacin', 'Anti-Bacterial Agents', 'Drug Resistance, Microbial', 'Drug Resistance, Multiple', 'Gentamicins', 'Kanamycin Resistance', 'Microbial Sensitivity Tests', 'Netilmicin', 'Staphylococcus aureus', 'Staphylococcus epidermidis'] | 8,837,369 | [['D09.408.051.476.060'], ['D27.505.954.122.085'], ['G06.225', 'G07.690.773.984.269'], ['G07.690.773.984.300'], ['D09.408.051.374'], ['G06.099.225.875', 'G06.225.347.875', 'G07.690.773.984.269.347.875'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D09.408.051.374.785.525'], ['B03.300.390.400.800.75... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Needle acupuncture in tension-type headache: a randomized, placebo-controlled study. | UNLABELLED: A study with needle acupuncture was performed in tension-type headache employing a new placebo acupunctureMETHOD: Sixty-nine patients (mean age 48.1 years, SD = 14.1) fulfilling the International Headache Society criteria for tension-type headache were randomly assigned to verum or placebo condition. No sig... | ['Acupuncture Therapy', 'Adult', 'Decision Trees', 'Depression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Needles', 'Placebos', 'Quality of Life', 'Single-Blind Method', 'Statistics, Nonparametric', 'Tension-Type Headache', 'Treatment Outcome'] | 11,531,895 | [['E02.190.044'], ['M01.060.116'], ['G17.162.500'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.612'], ['D26.660', 'E02.785'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.370.850', 'N05.715.360.325.730', 'N06.850.520.445.850'], ['E05.318.740.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Non-suicidal self-injury among prisoners: prevalence, risk factors, and prevention]. | BACKGROUND: Although non-suicidal self-injury (nssi) is a serious health concern among prisoners worldwide, no empirical data on this issue are currently available specifically for Belgium.<br/> AIM: To investigate the prevalence rates of, and risk factors for, nssi in Flemish prisons.<br/> METHOD: A cross-sectional st... | ['Adult', 'Belgium', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Prevalence', 'Prisoners', 'Risk Factors', 'Self-Injurious Behavior', 'Stress, Psychological'] | 30,536,293 | [['M01.060.116'], ['Z01.542.115'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['M01.729'], ['E05.318.740.600.800.725', 'N... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
PD1 blockade with pembrolizumab is highly effective in relapsed or refractory NK/T-cell lymphoma failing l-asparaginase. | Natural killer (NK)/T-cell lymphomas failing L-asparaginse regimens have no known salvage and are almost invariably fatal. Seven male patients with NK/T-cell lymphoma (median age, 49 years; range, 31-68 years) for whom a median of 2 (range, 1-5) regimens (including l-asparaginase regimens and allogeneic hematopoietic s... | ['Adult', 'Aged', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Asparaginase', 'DNA, Viral', 'Epstein-Barr Virus Infections', 'Gene Expression', 'Hematopoietic Stem Cell Transplantation', 'Herpesvirus 4, Human', 'Humans', 'Lymphoma, Extranodal NK-T-Cell', 'Male', 'Middle Aged', 'Positron-Emission Tomog... | 28,188,133 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['D08.811.277.087.116'], ['D13.444.308.568'], ['C01.925.256.466.313', 'C01.925.928.313'], ['G05.297'], ['E02.095.147.500.500.500', 'E04.936.225.687.500']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of Ecuador's cash transfer program (Bono de Desarrollo Humano) on child development in infants and toddlers: a randomized effectiveness trial. | We examined the effects of Ecuador's Bono de Desarrollo Humano (BDH)--an unconditional cash transfer program that was rolled-out using a randomized design--on health and development outcomes in very young children. Communities that were randomly assigned to the treatment group began receiving the BDH in 2004 and those ... | ['Adolescent', 'Adult', 'Child Development', 'Child, Preschool', 'Data Collection', 'Ecuador', 'Female', 'Financing, Government', 'Health Promotion', 'Humans', 'Infant', 'Male', 'Poverty', 'Social Class', 'Young Adult'] | 21,531,060 | [['M01.060.057'], ['M01.060.116'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.107.757.362'], ['N03.219.521.346'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['I01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Determining the radiation exposure from visual display terminals used in dentistry. | Computers are rapidly becoming incorporated into all aspects of dentistry, including administrative, didactic and research functions. Of particular concern for dentists are women of childbearing age who are regularly employed as receptionists and secretaries in private dental practices and teaching institutions. Thermo... | ['Adult', 'Canada', 'Computer Terminals', 'Female', 'Humans', 'Pregnancy', 'Radiation Dosage', 'Radiometry', 'United States'] | 2,021,894 | [['M01.060.116'], ['Z01.107.567.176'], ['L01.224.230.260.115.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.799'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Phonological coding in dyslexic readers. | A study was made of the ability of 9-, 12-, and 14-year-old dyslexics to recall auditorily presented rhyming and non-rhyming letter strings. These children showed a normal phonemic confusability effect, although overall their recall was much poorer than that of their chronological age controls; their recall levels were... | ['Adolescent', 'Child', 'Child Development', 'Discrimination Learning', 'Dyslexia', 'Humans', 'Memory', 'Mental Recall', 'Phonetics', 'Serial Learning', 'Speech Perception', 'Verbal Learning'] | 7,171,920 | [['M01.060.057'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.425.280'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150.550.200', 'F03.625.562.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Effect of Primary Breast Tumor Location on Axillary Nodal Positivity. | BACKGROUND: Variables such as tumor size, histology, and grade, tumor biology, presence of lymphovascular invasion, and patient age have been shown to impact likelihood of nodal positivity. The aim of this study is to determine whether primary location of invasive disease within the breast is associated with nodal posi... | ['Adenocarcinoma, Mucinous', 'Aged', 'Aged, 80 and over', 'Axilla', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'Female', 'Follow-Up Studies', 'Humans', 'Lymph Nodes', 'Lymphatic Metastasis', 'Middle Aged', 'Prognosis'] | 29,968,027 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.378.800.090'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.18... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1á,25(OH)(2)D(3). | 1á,25-Dihydroxyvitamin D3 (1á,25(OH)2D3) regulates osteoblasts through genomic and rapid membrane-mediated responses. Here we examined the interaction of protein disulfide isomerase family A, member 3 (Pdia3) and the traditional vitamin D receptor (VDR) in plasma membrane-associated responses to 1á,25(OH)2D3. We found ... | ['3T3 Cells', 'Animals', 'CSK Tyrosine-Protein Kinase', 'Caveolin 1', 'Cell Membrane', 'Mice', 'Osteoblasts', 'Protein Disulfide-Isomerases', 'Proteins', 'Receptors, Calcitriol', 'Signal Transduction', 'Vitamin D', 'src-Family Kinases'] | 23,896,121 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['D08.811.913.696.620.682.725.800.158'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['A11.284.149'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.329.629'], ['D08.811.399.475.800.550'], ... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of acid-induced amino acid decarboxylase gene expression by hns in Escherichia coli. | Biodegradative arginine decarboxylase and lysine decarboxylase, encoded by adi and cadA, respectively, are induced to maximal levels when Escherichia coli is grown anaerobically in rich medium at acidic pH. Mutants formed by transposon mutagenesis, namely, GNB725, GNB729, GNB88, GNB824, and GNB837, exhibited considerab... | ['Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Carboxy-Lyases', 'DNA Transposable Elements', 'DNA, Bacterial', 'DNA-Binding Proteins', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Genetic Complementation Test', 'Mutagenesis', 'Restriction Mapping'] | 8,381,784 | [['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['D08.811.520.224.125'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D13.444.308.212'], ['D12.776.260'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['E05.393.281.526'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The importance of applied ethology for the execution of animal welfare legislation]. | Applied ethology in general and farm animal ethology in particular have a great importance in connection with animal welfare regulations on a national and international level. They have through the legislation on animal welfare brought about important repercussions on housing of farm animals, wild animals and experimen... | ['Animal Husbandry', 'Animal Welfare', 'Animals', 'Animals, Domestic', 'Ethology', 'Europe', 'Germany', 'Housing, Animal', 'Sweden', 'Switzerland'] | 1,594,916 | [['J01.040.090'], ['I01.880.604.100'], ['B01.050'], ['B01.050.050.116'], ['F04.096.208'], ['Z01.542'], ['Z01.542.315'], ['J03.340.250', 'N06.230.150.360.250'], ['Z01.542.816.500'], ['Z01.542.883']] | ['Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
[Neonatal necrotizing enterocolitis (NEC). Observations of 21 cases studied from 1977 to 1980]. | We have carried out a study together with neonatologists, paediatricians, paediatric surgeons and paediatric radiologist on the etiopathogenic, clinical-statistical, therapeutical and evolutionary aspects of NEC during the period from 1977 to 1980 in the Neonatology Clinic and in the Paediatric Surgery Department Unive... | ['Enterocolitis, Pseudomembranous', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Radiography'] | 7,170,214 | [['C01.150.252.410.222.310', 'C06.405.205.596.800', 'C06.405.469.363.800'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['E01.370.350.700']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Duration of effect of interferon aerosol prophylaxis of vesicular stomatitis virus infection in mice. | Mice were exposed for 8 h to continuous small-particle aerosols containing natural mouse alpha interferon (estimated dosage 100 U per mouse) or one of two concentrations of hybrid recombinant alpha interferon A/D bgl (estimated dosages of 100 and 10,000 U per mouse, respectively). On days 1, 3, 5, 7, and 9 after exposu... | ['Aerosols', 'Animals', 'Interferon Type I', 'Lung', 'Male', 'Mice', 'Respiratory Tract Infections', 'Time Factors', 'Vesicular stomatitis Indiana virus', 'Virus Cultivation', 'Virus Diseases'] | 2,984,982 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['C01.748', 'C08.730'], ['G01.910.857'], ['B04.820.480.937.750.900.900'], ['E01.370.225.875.970', 'E05.200.875.970'], ['C01.925']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dual loss of USP10 and p14ARF protein expression is associated with poor prognosis in patients with small intestinal adenocarcinoma. | Oncogene-induced senescence occurs following oncogene activation in normal cells and is considered as a critical tumor-suppressing mechanism. Ubiquitin-specific protease 10 (USP10) has been reported to play a vital role in oncogene-induced senescence via the deubiquitination-dependent stabilization of p14ARF. However, ... | ['Adenocarcinoma', 'Adenocarcinoma, Mucinous', 'Biomarkers, Tumor', 'Carcinoma, Signet Ring Cell', 'DNA Methylation', 'Female', 'Follow-Up Studies', 'Genes, Tumor Suppressor', 'Humans', 'Intestinal Neoplasms', 'Intestine, Small', 'Lymphatic Metastasis', 'Male', 'Neoplasm Invasiveness', 'Oncogene Proteins', 'Prognosis',... | 30,375,264 | [['C04.557.470.200.025'], ['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['D23.101.140'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.360.34... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses. | CD8(+) T cells directed against conserved viral regions elicit broad immunity against distinct influenza viruses, promote rapid virus elimination and enhanced host recovery. The influenza neuraminidase inhibitor, oseltamivir, is prescribed for therapy and prophylaxis, although it remains unclear how the drug impacts di... | ['Adolescent', 'Adult', 'Animals', 'Antiviral Agents', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Child', 'Child, Preschool', 'Female', 'Ferrets', 'Humans', 'Infant', 'Inflammation', 'Influenza A Virus, H1N1 Subtype', 'Influenza, Human', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Orthomyxoviridae Infectio... | 26,086,392 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D27.505.954.122.388'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.1... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ACOG Practice Bulletin No. 108: Polycystic ovary syndrome. | Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. Its etiology remains unknown, and treatment is largely symptom based and empirical. PCOS has the potential to cause substantial metabolic sequelae, including an increased risk of diabetes and... | ['Contraceptives, Oral, Combined', 'Diabetes Mellitus, Type 2', 'Female', 'Hirsutism', 'Humans', 'Hyperandrogenism', 'Hypoglycemic Agents', 'Polycystic Ovary Syndrome'] | 19,888,063 | [['D26.310.360', 'D27.505.696.875.360.276.210.100', 'D27.505.954.705.360.276.210.100'], ['C18.452.394.750.149', 'C19.246.300'], ['C17.800.329.750', 'C23.888.971.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.706.316.064.500', 'C12.706.316.090.750', 'C13.351.875.253.064.500', 'C13.351.875.253.090.750', 'C... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three parties, one direction: Research priorities in adults with congenital heart disease. What do professionals, patients and relatives want to know? | BACKGROUND: Patients, their relatives, as well as medical specialists from the fields of paediatric cardiology, cardiology and cardiac surgery were surveyed to investigate the current research needs in the field of congenital heart disease (CHD) focussing specifically on the needs of those affected.MATERIAL AND METHODS... | ['Adolescent', 'Adult', 'Cardiology', 'Family', 'Heart Defects, Congenital', 'Humans', 'Middle Aged', 'Patient Participation', 'Physicians', 'Registries', 'Research', 'Surveys and Questionnaires', 'Young Adult'] | 26,803,251 | [['M01.060.057'], ['M01.060.116'], ['H02.403.429.163'], ['F01.829.263', 'I01.880.853.150'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.360.300', 'N05.3... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Chemical Composition and In Vitro | The essential oil was obtained by hydrodistillation and the identification and quantification of components were achieved with the use of GC-MS analysis. The antioxidant activity was evaluated by the method of sequestration of DPPH. Essential oils were used for study the cytotoxic front larvae of Artemia salina. In the... | ['Aedes', 'Animals', 'Anti-Infective Agents', 'Antioxidants', 'Artemia', 'Escherichia coli', 'Insecticides', 'Larva', 'Mentha piperita', 'Oils, Volatile', 'Plant Oils'] | 28,116,346 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['D27.505.954.122'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.050.500.131.365.060.050'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.720.031.700.491', 'D27.888.723.491'], ['B05.500.500', 'G07.345.500.550... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Circus movement in rabbit atrial muscle as a mechanism of tachycardia. II. The role of nonuniform recovery of excitability in the occurrence of unidirectional block, as studied with multiple microelectrodes. | Periods of tachycardia were induced in isolated segments (15 X 15 mm) of rabbit left atrium by local application of a properly timed premature stimulus. We used a special device for multiple synchronous microelectrode recordings of responses of more than 100 fibers during the initiation of tachycardia. We clearly demon... | ['Action Potentials', 'Animals', 'Heart Atria', 'Heart Block', 'In Vitro Techniques', 'Rabbits', 'Refractory Period, Electrophysiological', 'Tachycardia'] | 939,001 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A07.541.358'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['E05.481'], ['B01.050.150.900.649.313.968.700'], ['G07.265.753.770', 'G07.265.760', 'G11.561.601.770', 'G11.561.785'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term dynamics of tropical walking sticks in response to multiple large-scale and intense disturbances. | Understanding the effects of disturbance and secondary succession on spatio-temporal patterns in the abundance of species is stymied by a lack of long-term demographic data, especially in response to infrequent and high intensity disturbances, such as hurricanes. Moreover, resistance and resilience to hurricane-induced... | ['Animals', 'Cyclonic Storms', 'Ecosystem', 'Humidity', 'Insecta', 'Piper', 'Puerto Rico', 'Rain', 'Species Specificity', 'Temperature', 'Time Factors', 'Trees'] | 20,677,015 | [['B01.050'], ['G16.500.175.500', 'N06.230.100.230.100'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['B01.050.500.131.617'], ['B01.650.940.800.575.912.250.812.666'], ['Z01.107.084.900.750', 'Z01.639.880.750'], ['G16.500.175.859'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Application of arterial duct stent in ductus-dependent hypoplastic right heart syndrome]. | Objective: To summarize the experience of arterial duct (AD) stenting in children with ductus-dependent hypoplastic right heart syndrome (HRHS). Methods: Seven children including 4 cases of pulmonary atresia with intact ventricular septum (PA-IVS) with HRHS and 3 cases of critical pulmonary stenosis (CPS)-IVS with HRHS... | ['Cardiac Catheterization', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Infant, Newborn', 'Pulmonary Atresia', 'Pulmonary Valve Stenosis', 'Retrospective Studies', 'Stents', 'Treatment Outcome'] | 32,234,140 | [['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C14.240.850.937', 'C14.280.484.640', 'C16.131.240.850.906'], ['C14.280.484.716', 'C14.280.955.750'], ['E05.318.372.500.500.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cryopreservation of ram semen with antioxidant supplemented soybean lecithin-based extenders and impacts on incubation resilience. | The scope of this study was investigation the affects of various antioxidants on 1% soybean lecithin-based semen extenders for ram semen cryopreservation. Ejaculates, collected via electrically stimulated ejaculation, that have a thick consistency, rapid wave motion (3-5 on a 0-5 scale) and >75% initial motility were p... | ['Acrosome', 'Animals', 'Antioxidants', 'Cryopreservation', 'Cryoprotective Agents', 'Cysteamine', 'Cysteine', 'Freezing', 'In Situ Nick-End Labeling', 'Lecithins', 'Male', 'Semen', 'Semen Preservation', 'Sheep', 'Soybeans', 'Sperm Motility'] | 27,157,891 | [['A05.360.490.890.820.100', 'A11.284.430.214.190.875.190.550.040', 'A11.497.760.400.100'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['D2... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The role of hypoxia in the effect of glucose load on irradiated tumor cells]. | In experiments on Ehrlich ascites tumor cells it was shown that hypoxia, which reduces the lethal effect of gamma-rays, can considerably enhance the injury of cells by glucose. Treatment of tumor cells with glucose in hypoxic conditions followed by exposure to ionizing radiation under both hypoxia and normal aeration c... | ['Animals', 'Carcinoma, Ehrlich Tumor', 'Cells, Cultured', 'Dose-Response Relationship, Radiation', 'Glucose', 'Mice', 'Oxygen', 'Radiation Tolerance'] | 4,001,318 | [['B01.050'], ['C04.557.470.200.200', 'C04.619.169'], ['A11.251'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.992.635.505.500'], ['D01.268.185.550', 'D01.362.670'], ['G04.712', 'G07.738']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantitative fecal recovery of ingested hemoglobin-heme in blood: comparisons by HemoQuant assay with ingested meat and fish. | Blood, meat, or fish, or any combination thereof, were ingested by 9 normal volunteers to permit studies of the contained hemes during total gastrointestinal transit. Quantitative analysis of ingested heme and of fecal heme and its degradation products was made possible by a new specific and extremely sensitive test, H... | ['Administration, Oral', 'Adult', 'Aged', 'Animals', 'Feces', 'Female', 'Fishes', 'Heme', 'Hemoglobins', 'Humans', 'Male', 'Meat', 'Methods', 'Middle Aged', 'Occult Blood'] | 4,007,402 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['A12.459'], ['B01.050.150.900.493'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Complications following renal trauma. | OBJECTIVES: To evaluate and compare the incidence and type of kidney-related complications among different modes of management for kidney injuries.DESIGN: Trauma registry and medical record review study.SETTING: Level I trauma center in Los Angeles, California.PATIENTS: All patients with renal trauma injuries treated f... | ['Adult', 'Female', 'Humans', 'Incidence', 'Kidney', 'Laparotomy', 'Male', 'Nephrectomy', 'Trauma Severity Indices', 'Wounds, Nonpenetrating', 'Wounds, Penetrating', 'Young Adult'] | 20,404,289 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A05.810.453'], ['E04.406'], ['E04.950.774.435'], ['E05.318.308.940.968.875', 'E05.944', 'N04.452.859.564.800', 'N05.715.360.300.715.500.8... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Maternal assessment in the prediction of intrauterine infection in preterm prelabor amniorrhexis. | The objective of this study was to evaluate maternal temperature, heart rate, leukocyte count and C-reactive protein in the prediction of fetal bacteraemia and positive amniotic fluid cultures in 75 pregnancies complicated by preterm prelabor amniorrhexis. Cordocentesis and amniocentesis were performed and fetal blood ... | ['Amniocentesis', 'Amniotic Fluid', 'Bacteremia', 'Bacteria', 'C-Reactive Protein', 'Candida albicans', 'Cordocentesis', 'Female', 'Fetal Blood', 'Fetal Membranes, Premature Rupture', 'Fever', 'Heart Rate', 'Humans', 'Infections', 'Leukocyte Count', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Uterine Diseases'... | 7,576,165 | [['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['A12.098', 'A16.378.149'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['B03'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alterations of the immune system following splenectomy in childhood. | After splenectomy due to blunt abdominal trauma, splenectomized children showed a restricted pattern of T-cell immunodeficiency compared to age and sex-matched normal children. Peripheral blood total (CD3) T-cell counts of 11 splenectomized children of 43%, double positive helper (CD4) inducer subpopulation (CD29) cell... | ['Adolescent', 'Adult', 'Age Factors', 'Autoantibodies', 'Child', 'Female', 'Humans', 'Immunity', 'Immunoglobulins', 'Lymphocyte Activation', 'Lymphocyte Subsets', 'Male', 'Splenectomy', 'T-Lymphocytes'] | 2,002,522 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mechanism of the lipid-lowering effect of ethyl all-cis-5,8,11,14,17-icosapentaenoate. | The effect of highly purified ethyl all-cis-5,8,11,14,17-icosapentaenoate (EPA-E) on cholesterol metabolism in rats was examined to clarify the mechanism of its hypolipidemic action. Pretreatment with EPA-E reduced the increase in plasma radioactivity after oral administration of [14C]cholesterol. The conversion of [14... | ['Administration, Oral', 'Animals', 'Bile', 'Cholesterol', 'Eicosapentaenoic Acid', 'Hydroxymethylglutaryl CoA Reductases', 'Intestinal Absorption', 'Lipoproteins', 'Liver', 'Male', 'Metabolic Clearance Rate', 'Microsomes, Liver', 'Rats', 'Rats, Wistar'] | 8,444,276 | [['E02.319.267.100'], ['B01.050'], ['A12.200.087'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10.212.302.380.410.385', 'D10.251.355.255.200', 'D10.251.355.337.290', 'D10.627.430.450.390'], ['D08.811.682.047.820.150.415'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.65... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cicatricial ectropion secondary to herpes zoster. | We present three patients with cicatricial ectropion of the upper and lower lids secondary to herpes zoster. Surgical release of the lid traction, excision of scars, and full thickness skin grafting were performed with satisfactory results. | ['Adolescent', 'Aged', 'Cicatrix', 'Ectropion', 'Female', 'Herpes Zoster Ophthalmicus', 'Humans', 'Male', 'Skin Transplantation'] | 6,358,990 | [['M01.060.057'], ['M01.060.116.100'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['C11.338.362'], ['C01.375.725.450', 'C01.925.256.466.930.750.466', 'C01.925.325.450', 'C11.294.800.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. | The plant pathogenesis related proteins group 1 (PR-1) and a variety of related mammalian proteins constitute a PR-1 protein family that share sequence and structural similarities. GAPR-1 is a unique family member as thus far it is the only PR-1 family member that is not co-translationally targeted to the lumen of the ... | ['Amino Acid Sequence', 'Animals', 'CHO Cells', 'Cricetinae', 'Crystallization', 'Crystallography, X-Ray', 'Dimerization', 'Golgi Apparatus', 'Humans', 'Membrane Proteins', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Protein Conformation', 'Sequence Homology, Amino Acid', 'Two-Hybrid System Techniques'] | 15,123,429 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['G02.206', 'G03.230'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['L01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A Strategy for Quality Control of Vespa magnifica | As a folk medicine of the Jingpo minority in Yunnan province, the venom of Vespa magnifica has been commonly used for the treatment of rheumatoid arthritis. Quality standardization of the wasp venom is a necessary step for its pharmaceutical research and development. To control the quality of the wasp venom, a method b... | ['Amino Acid Sequence', 'Animals', 'Anti-Inflammatory Agents', 'Arthritis, Rheumatoid', 'Chromatography, High Pressure Liquid', 'Humans', 'Medicine, Chinese Traditional', 'Medicine, Traditional', 'Peptide Mapping', 'Peptides', 'Principal Component Analysis', 'Quality Control', 'Serotonin', 'Wasp Venoms', 'Wasps'] | 31,408,988 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.158'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['E02.190.488', 'I01.076.201.450.654'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 |
Argyrophilic cells in 202 human mucinous breast carcinomas. Relation to histopathologic and clinical factors. | Two hundred two human, mucinous breast carcinomas were investigated for the presence of argyrophilic granules, and these granules were found in 25% of the cases. The granules were located in the cytoplasm and were heterogeneously distributed within the tumors. Tumors with granules were otherwise morphologically indisti... | ['APUD Cells', 'Adenocarcinoma, Mucinous', 'Apudoma', 'Breast Neoplasms', 'Carcinoid Tumor', 'Cytoplasmic Granules', 'Female', 'Humans', 'Parity', 'Prognosis', 'Receptors, Estrogen', 'Silver Nitrate', 'Staining and Labeling'] | 2,416,216 | [['A11.382.249'], ['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['C04.557.465.625.650.135', 'C04.557.470.035.250', 'C04.557.580.625.650.135'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Dornier Compact Delta lithotripter: the first 150 ureteral calculi. | BACKGROUND AND PURPOSE: Shockwave lithotripsy (SWL) is the least invasive treatment for ureteral calculi and is the best accepted by patients and clinicians. This prospective study was performed to evaluate the results of SWL for all ureteral calculi.PATIENTS AND METHODS: Between April 1999 and May 2000, there were 150... | ['Adult', 'Aged', 'Cohort Studies', 'Equipment Design', 'Equipment Safety', 'Female', 'Follow-Up Studies', 'Humans', 'Length of Stay', 'Lithotripsy, Laser', 'Male', 'Middle Aged', 'Pain Measurement', 'Probability', 'Prospective Studies', 'Reference Values', 'Sensitivity and Specificity', 'Severity of Illness Index', 'S... | 12,490,016 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.320'], ['E05.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Chronic pancreatitis in the Br?dno district of Warsaw]. | A retrospective epidemiological-clinical analysis of patients with chronic pancreatitis living in the Br?dno District of Warsaw is reported. It was found that the approximated coefficients of morbidity and incidence per 100 thousand of the population in 1987 were 17.0 and 5.0 respectively, and they were similar to thos... | ['Adult', 'Alcoholism', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis', 'Poland', 'Retrospective Studies'] | 2,631,439 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689.750'], ['Z01.542.248.679'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of continuous LDL apheresis with dextran-sulfate cellulose column system on a child with homozygous familial hypercholesterolemia. | A new system for selective low density lipoprotein apheresis with an automated regenerating column using dextran-sulfate (DS) as ligand was evaluated for six months in a 13-year-old boy homozygous for familial hypercholesterolemia. Two columns each containing 150 ml of DS cellulose were alternately used after rinsing w... | ['Adolescent', 'Cholesterol, LDL', 'Dextran Sulfate', 'Dextrans', 'Humans', 'Hyperlipoproteinemia Type II', 'Male', 'Plasmapheresis'] | 1,696,057 | [['M01.060.057'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['D09.698.365.272.300'], ['D05.750.078.562.272', 'D09.698.365.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.398.481', 'C18.452.584.500.500.644.475', 'C18.452.648.398.481'], ['E02.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis of monoesters of pyrroloquinoline quinone and imidazopyrroloquinoline, and radical scavenging activities using electron spin resonance in vitro and pharmacological activity in vivo. | Monoesters with the ester groups at C-2 of pyrroloquinoline quinone (PQQ) and C-9 of imidazopyrroloquinoline (IPQ) were synthesized, and radical scavenging activities of coenzyme PQQ, IPQ compounds synthesized from PQQ and various amino acids, and monoesters of PQQ and IPQ were studied in vitro and in vivo. PQQ and PQQ... | ['Administration, Oral', 'Animals', 'Biological Assay', 'Carbon Tetrachloride', 'Cataract', 'Chemical and Drug Induced Liver Injury', 'Chick Embryo', 'Coenzymes', 'Electron Spin Resonance Spectroscopy', 'Esters', 'Free Radical Scavengers', 'Free Radicals', 'Hydroxyl Radical', 'Injections, Intraperitoneal', 'Liver', 'Li... | 9,151,238 | [['E02.319.267.100'], ['B01.050'], ['E05.091'], ['D02.455.526.439.150'], ['C11.510.245'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['A13.350.150', 'A16.331.200'], ['D08.211'], ['E05.196.867.519.274'], ['D02.241.400'], ['D27.505.519.217.500'], ['D01.339', 'D02.389'], ['D01.045.250.357', 'D01.248.497.158.459.300', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Method to Detect Cytochrome c Oxidase Activity and Mitochondrial Proteins in Oligodendrocytes. | Cytochrome c oxidase or mitochondrial respiratory chain complex IV is where over 90% of oxygen is consumed. The relationship between complex IV activity and mitochondrial proteins, which provides a guide to understanding the mechanisms in primary mitochondrial disorders, has been determined by histochemistry (complex I... | ['Animals', 'Central Nervous System', 'Electron Transport Complex IV', 'Humans', 'Immunohistochemistry', 'Mitochondrial Proteins', 'Oligodendroglia', 'Rats', 'Single-Cell Analysis'] | 30,820,908 | [['B01.050'], ['A08.186'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.7... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Stimulation and inhibition of interferon-beta production of human diploid fibroblasts by foodstuffs. | We screened for foodstuffs affecting interferon-beta (IFN-beta) production of human foreskin diploid fibroblasts, in the presence of poly I.poly C, cycloheximide, and actinomycin D. alpha- and beta-caseins stimulated IFN-beta production dose-dependently, but kappa-casein inhibited it. Of the two chymosin fragments of k... | ['Blood', 'Caseins', 'Cells, Cultured', 'Collagen', 'Culture Media', 'Enzyme-Linked Immunosorbent Assay', 'Epidermal Growth Factor', 'Fibroblasts', 'Food', 'Guanosine Monophosphate', 'Humans', 'Interferon Type I', 'Lactoferrin', 'Lactoglobulins'] | 1,369,307 | [['A12.207.152', 'A15.145'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D27.720.470.305', 'E07.206'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D06.472.317.350', 'D12.644.276.382.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Results of preoperative chemoradiotherapy for patients with advanced cancer of the nasal cavity and paranasal sinuses. | OBJECTIVES: Curative treatment of nasal cavity and paranasal sinus cancer is challenging due to the proximity to critical anatomical structures. The purpose of this study was to analyze the impact of trimodality therapy with preoperative chemotherapy and reduced-dose radiotherapy followed by organ-preserving surgery fo... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma', 'Chemoradiotherapy, Adjuvant', 'Female', 'Humans', 'Male', 'Middle Aged', 'Paranasal Sinus Neoplasms', 'Retrospective Studies', 'Sweden', 'Young Adult'] | 28,749,194 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200'], ['E02.186.079.500', 'E02.319.164.500', 'E02.815.160.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.443.665.650.693', 'C08.460.669.693', 'C08.460.692.503', 'C08.785.600.693', 'C09... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
How do pre-adolescent children interpret conditionals? | Studies examining children's basic understanding of conditionals have led to very different conclusions. On the one hand, conditional inference tasks suggest that young children are able to interpret familiar conditionals in a complex manner. In contrast, truth-table tasks suggest that before adolescence, children have... | ['Child', 'Child Development', 'Comprehension', 'Concept Formation', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Thinking'] | 27,125,222 | [['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.188.357'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.785']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nano polyurethane-assisted ultrasensitive biodetection of H(2)O(2) over immobilized microperoxidase-11. | Nanostructured polyurethane (PU) synthesized by an emulsion polymerization with narrow size distribution was employed for the first time directly as a novel matrix for enzyme immobilization to develop sensitively amperometric biosensors. When Microperoxidase-11 (MP-11) was selected as a model protein, the resulting hyd... | ['Biosensing Techniques', 'Electrochemical Techniques', 'Enzymes, Immobilized', 'Hydrogen Peroxide', 'Microscopy, Electron, Transmission', 'Nanostructures', 'Peroxidases', 'Polyurethanes'] | 21,855,316 | [['E05.601.043'], ['E05.301'], ['D08.811.180', 'D12.776.463.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512'], ['D08.811.682.732'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of temporal and spatial variability on the classification of the Ecological Quality Status using the CARLIT Index. | Methodologies developed by European Member States to assess the environmental quality of their coastal waters under the EU Water Framework Directive (WFD, 2000/60/EC) may have an associated source of uncertainty. Here we identify and quantify the level of uncertainty in the CARLIT (Cartography of littoral and upper-sub... | ['Ecology', 'Ecosystem', 'Environment', 'Environmental Monitoring', 'European Union', 'Reproducibility of Results', 'Uncertainty', 'Water Quality'] | 26,639,652 | [['H01.158.273.248', 'H01.277.249'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275', 'N06.230'], ['N06.850.460.350.080', 'N06.850.780.375'], ['I01.615.500.475'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.715.3... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
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