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Sonography of pediatric neck masses. | Duplex/color Doppler ultrasound is the imaging modality of choice for the evaluation of soft tissue masses of the pediatric neck. Information regarding the size, shape, borders, location, internal consistency and vascularity of the mass, and its relationship to the major neck vessels may be rapidly obtained. If the les... | ['Child', 'Connective Tissue Diseases', 'Head and Neck Neoplasms', 'Humans', 'Neck', 'Ultrasonography'] | 19,730,051 | [['M01.060.406'], ['C17.300'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.598'], ['E01.370.350.850']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Hemiplegic patients. Nursing at home]. | By daily performing the seven easy exercises in the rehabilitation program which the authors of this article propose, a patient afflicted by an "ACV" can prevent the appearance of the typical motor skill limitations which appear a while after the onset of the illness. | ['Community Health Nursing', 'Exercise Therapy', 'Hemiplegia', 'Home Care Services', 'Humans'] | 10,745,867 | [['H02.478.676.150', 'N02.421.143.150'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['C10.597.622.295', 'C23.888.592.636.312'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Acquired affective-evaluative value: conservative but not unchangeable. | In a previous study on Evaluative Conditioning it was found that unlike signal-learning, evaluative learning is resistant to extinction. In the present experiment we tried to replicate and corroborate this finding. In addition, we investigated the effectiveness of a counterconditioning procedure to alter acquired evalu... | ['Cognition', 'Conditioning, Classical', 'Emotions', 'Extinction, Psychological', 'Female', 'Humans', 'Male'] | 2,730,509 | [['F02.463.188'], ['F02.463.425.179.308'], ['F01.470'], ['F02.463.425.770.232'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trends in educational inequalities in old age mortality in Norway 1961-2009: a prospective register based population study. | BACKGROUND: The vast majority of deaths occur in older adults. Paradoxically, knowledge on long-term trends in mortality inequalities among the aged, and particularly for those aged 80 years and over, is sparse. The historical trends in size and impact of socioeconomic inequalities on old age mortality are important to... | ['Age Distribution', 'Aged', 'Aged, 80 and over', 'Educational Status', 'Female', 'Humans', 'Male', 'Mortality', 'Norway', 'Prospective Studies', 'Registries', 'Risk'] | 23,101,942 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['Z01.542.816.374'], ['E05.318.372.500.750.625', 'N05.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Ketone body utilization in duodenum. Differential effect of fasting on lipogenesis from acetoacetate and 3-hydroxybutyrate. | The effect of fasting and refeeding on oxidation, lipogenesis and amino acid synthesis from ketone bodies has been studied in neonatal chick duodenal mucosa. Oxidation and amino acid synthesis were higher from acetoacetate and were stimulated by fasting from both 3-hydroxybutyrate and acetoacetate. On the contrary, lip... | ['3-Hydroxybutyric Acid', 'Acetate-CoA Ligase', 'Acetoacetates', 'Amino Acids', 'Animals', 'Chickens', 'Cytosol', 'Duodenum', 'Fasting', 'Hydroxybutyrates', 'Ketone Bodies', 'Lipids', 'Male'] | 2,575,906 | [['D02.241.081.114.937.349', 'D02.241.511.429.349', 'D02.522.585.087', 'D10.251.400.143.781.500'], ['D08.811.464.267.500.200'], ['D02.241.755.080', 'D02.522.585.175'], ['D12.125'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.45... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RENEB biodosimetry intercomparison analyzing translocations by FISH. | PURPOSE: In the framework of RENEB, several biodosimetry exercises were conducted analyzing different endpoints. Among them, the analysis of translocations is considered the most useful method for retrospective biodosimetry due to the relative stability of their frequency with post irradiation time. The aim of this stu... | ['Biological Assay', 'Europe', 'Humans', 'In Situ Hybridization, Fluorescence', 'Lymphocytes', 'Quality Assurance, Health Care', 'Radiation Exposure', 'Radiation Monitoring', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Translocation, Genetic'] | 27,705,052 | [['E05.091'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Observation of gastric variceal flow characteristics by endoscopic ultrasonography using color Doppler. | OBJECTIVES: The aim of this study was to investigate the endoscopic color Doppler ultrasonography (ECDUS) findings of gastric varices and to determine the role of ECDUS in the diagnosis of gastric varices.METHODS: Using ECDUS, we evaluated 114 patients with gastric varices found consecutively by routine upper endoscopy... | ['Aged', 'Aged, 80 and over', 'Blood Flow Velocity', 'Collateral Circulation', 'Endosonography', 'Esophageal and Gastric Varices', 'Female', 'Humans', 'Hypertension, Portal', 'Male', 'Middle Aged', 'Stomach', 'Ultrasonography, Doppler, Color'] | 18,028,507 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.248'], ['E01.370.350.850.280'], ['C06.405.117.240', 'C06.552.494.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['M01.060.116.630'], ['A03.556.875.875'], ['E01.370.350.850.850.850.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence and Factors Associated with Pelvic Organ Prolapse among Pedestrian Back-Loading Women in Bench Maji Zone. | Background: It is common to see women carrying heavy loads on their back in developing countries including Ethiopia. This may have an effect on pelvic organ prolapse. The objective of this study was to determine prevalence and factors associated with pelvic organ prolapse among pedestrian back-loading women in Bench-Ma... | ['Adolescent', 'Adult', 'Age Factors', 'Body Mass Index', 'Cross-Sectional Studies', 'Developing Countries', 'Ethiopia', 'Female', 'Humans', 'Lifting', 'Logistic Models', 'Middle Aged', 'Odds Ratio', 'Pedestrians', 'Pelvic Organ Prolapse', 'Prevalence', 'Risk Factors', 'Surveys and Questionnaires', 'Young Adult'] | 29,217,925 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.615.500.300'], ['Z01.058.290.120.310'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adolescents who experienced negative alcohol-related consequences are willing to experience these consequences again in the future. | Alcohol use and risky single occasion drinking are common among adolescents and are associated with a higher risk of various negative social, physical, academic, or sexual consequences. Studies have shown that among college students, willingness to experience negative consequences is associated with a higher likelihood... | ['Adolescent', 'Adolescent Behavior', 'Alcohol Drinking', 'Alcoholic Intoxication', 'Female', 'Health Risk Behaviors', 'Humans', 'Male', 'Preventive Health Services', 'Sexual Behavior', 'Social Behavior', 'Students', 'Universities'] | 29,389,210 | [['M01.060.057'], ['F01.145.022'], ['F01.145.317.269'], ['C25.775.100.175', 'F03.900.100.300'], ['F01.145.488.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726'], ['F01.145.802'], ['F01.145.813'], ['M01.848'], ['I02.783.830', 'J03.832.830']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
High-throughput screening for ligand-induced c-fos mRNA expression by branched DNA assay in Chinese hamster ovary cells. | We have developed a generally useful screening assay for receptor agonists and antagonists in Chinese Hamster Ovary (CHO) cells. Three key features of the assay make it applicable to a broad range of receptors: (1) the use of CHO cells as host cells to overexpress receptors, (2) measurement of endogenous c-fos mRNA, wh... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'CHO Cells', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cricetinae', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation', 'Genes, fos', 'Genetic Techniques', 'Insulin', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated P... | 9,887,223 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A11.251.210.200', 'A11.436.155'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['B01.050.150.900.649.313.992.635.075... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Tyndallometry in patients with diabetic macular edema before and after central laser coagulation]. | BACKGROUND: It is known that the breakdown of the blood-retina-barrier (BRB) as well as the blood-aqueous-barrier (BAB) is one of the earliest pathopysiological changes in the diabetic eye. Some previous studies confirmed a statistically significant increase of flare values of the aqueous humor in eyes with diabetic re... | ['Aged', 'Aqueous Humor', 'Blood-Aqueous Barrier', 'Blood-Retinal Barrier', 'Diabetic Retinopathy', 'Eye Proteins', 'Female', 'Fluorescein Angiography', 'Humans', 'Macular Edema', 'Male', 'Middle Aged', 'Postoperative Complications'] | 9,541,892 | [['M01.060.116.100'], ['A09.371.060.067.070', 'A12.207.270.040'], ['A07.030', 'A09.371.894.030'], ['A07.040', 'A09.371.729.055'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['D12.776.306'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439.245... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A simple method for monitoring protein-DNA interactions. | A simple, efficient and cheap method is reported for monitoring interactions between single stranded desoxyribonucleic acids and proteins, using fluorescence spectroscopy and complexes of 5'-dye-DNA conjugates with bovine serum albumin as probes. In the presence of a single stranded DNA-binding protein the complexes wi... | ['Animals', 'Cattle', 'DNA, Single-Stranded', 'DNA-Binding Proteins', 'Fluorescent Dyes', 'Naphthalenes', 'Protein Binding', 'Serum Albumin, Bovine', 'Spectrometry, Fluorescence'] | 19,414,256 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D12.776.260'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D02.455.426.559.847.638', 'D04.615.638'], ['G02.111.679', 'G03.808'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['E05.196.712... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Culture of a differentiated liver cell line, Hep G2, in serum with application to a bioartificial liver: effect of supplementation of serum with amino acids. | Much effort has been directed toward the development of serum-free, hormonally defined culture conditions for the maintenance of differentiated functions in many cell types, including hepatocytes. However, in the development of a hepatocyte bioreactor for artificial liver support, many designs propose the maintenance o... | ['Amino Acids', 'Artificial Organs', 'Blood', 'Carcinoma, Hepatocellular', 'Cell Differentiation', 'Cell Division', 'Cell Survival', 'Culture Media', 'Cysteine', 'Glutamic Acid', 'Glutathione', 'Glycine', 'Humans', 'Liver', 'Liver Neoplasms', 'Tumor Cells, Cultured'] | 7,993,197 | [['D12.125'], ['E07.858.082'], ['A12.207.152', 'A15.145'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['D27.720.470.305', 'E07.206'], ['D02.886.030.230', 'D02.886.489.155', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic epileptic encephalopathy in adult patients with bilaterally synchronous frequent and/or prolonged subclinical epileptiform discharges. | We followed four patients with infrequent convulsive seizures for four to 10 years, with periodic EEGs and neuropsychological tests. All four had bursts of frontally predominant, bilaterally synchronous 1.5-3-Hz spike or polyspike and slow-wave discharges (SWDs) that initially comprised 15% to 88% but were reduced to 5... | ['Aged', 'Brain', 'Brain Mapping', 'Chronic Disease', 'Cortical Synchronization', 'Electroencephalography', 'Epilepsy, Generalized', 'Functional Laterality', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Retrospective Studies', 'Veterans'] | 23,021,092 | [['M01.060.116.100'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C23.550.291.500'], ['E01.370.376.300.437.500', 'E01.370.405.245.575.500', 'G07.265.256.249'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375'], ['F02.830.297.425', 'G11.561.225.425'], ['B01... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Review of Desulfotomaculum species and proposal of the genera Desulfallas gen. nov., Desulfofundulus gen. nov., Desulfofarcimen gen. nov. and Desulfohalotomaculum gen. nov. | The genus Desulfotomaculumis a heterogeneous group of spore-forming sulfate-reducing bacteria. The type species of the genus is Desulfotomaculum nigrificans (Approved Lists 1980) emend. Visser et al. 2014. The results of phylogenetic analysis demonstrated that the genus Desulfotomaculum already has lost the clustering ... | ['Bacterial Typing Techniques', 'DNA, Bacterial', 'Desulfotomaculum', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA'] | 30,028,279 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D13.444.308.212'], ['B03.353.625.782.297', 'B03.510.415.400.230', 'B03.900.300'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['E05.393.760.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Modulation of glycine affinity for NMDA receptors by extracellular Ca2+ in trigeminal neurons. | Glycine and the divalent cation Ca2+ play key roles in regulating the activity of excitatory amino acid NMDA receptor channels. There is accumulating evidence that the concentration of glycine at the synaptic cleft is below a saturated level. We examined the effect of external Ca2+ on NMDA responses in various concentr... | ['Animals', 'Binding, Competitive', 'Calcium', 'Drug Synergism', 'Electrophysiology', 'Extracellular Space', 'Glycine', 'N-Methylaspartate', 'Neurons', 'Osmolar Concentration', 'Rats', 'Rats, Inbred Strains', 'Receptors, N-Methyl-D-Aspartate', 'Trigeminal Nucleus, Spinal'] | 8,027,794 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.690.773.968.477'], ['H01.158.344.528', 'H01.158.782.236'], ['A10.082.500', 'A11.284.295'], ['D12.125.481'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['A08.675', 'A11.671'], ['G02.640'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Second primary malignancies in thyroid cancer patients. | The late health effects associated with radioiodine ((131)I) given as treatment for thyroid cancer are difficult to assess since the number of thyroid cancer patients treated at each centre is limited. The risk of second primary malignancies (SPMs) was evaluated in a European cohort of thyroid cancer patients. A common... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Cohort Studies', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Neoplasms, Second Primary', 'Risk Factors', 'Thyroid Neoplasms'] | 14,583,762 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of Cell Viability with Single-, Dual-, and Multi-Staining Methods Using Image Cytometry. | The ability to accurately measure cell viability is important for any cell-based assay. Traditionally, viability measurements have been performed using the trypan blue exclusion method on a hemacytometer, which allows researchers to visually distinguish viable from nonviable cells. While the trypan blue method can work... | ['Cell Count', 'Cell Survival', 'Fluorescent Dyes', 'HeLa Cells', 'Humans', 'Image Cytometry', 'Jurkat Cells', 'MCF-7 Cells', 'Nucleic Acids', 'Staining and Labeling', 'Time Factors', 'Trypan Blue'] | 28,470,515 | [['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.386.400', 'E05.196.712.516.600.240.400', 'E05.200.500.386.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of trimethoprim on sodium transport across the frog skin epithelium. | Trimethoprim, a dihydrofolate reductase inhibitor, is used as a therapeutical agent in combination with sulfamethoxazole. Studies of the interaction of trimethoprim with membrane transport are rare. This paper presents a study of the effect of trimethoprim on the short-circuit current (Isc) and on the transepithelial t... | ['Amiloride', 'Animals', 'Biological Transport', 'Chlorides', 'Culture Media', 'Dose-Response Relationship, Drug', 'Epithelium', 'In Vitro Techniques', 'Kinetics', 'Membrane Potentials', 'Rana ridibunda', 'Skin', 'Skin Physiological Phenomena', 'Sodium', 'Sodium Channels', 'Sodium Radioisotopes', 'Trimethoprim', 'Trime... | 1,664,336 | [['D03.383.679.149'], ['B01.050'], ['G03.143'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D27.720.470.305', 'E07.206'], ['G07.690.773.875', 'G07.690.936.500'], ['A10.272'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['B01.050.150.900.090.180.708.360'], ['A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thymus-independent expression of a truncated T cell receptor-alpha mRNA in murine kidney. | During studies on gene expression in the kidney, we unexpectedly observed that murine kidney expresses a truncated form of TCR-alpha mRNA (1.3-1.4 kb). This transcript was not associated with the presence of complete TCR-alpha mRNA (1.7 kb) or detectable TCR-beta or -delta transcripts, thus indicating that the truncate... | ['Animals', 'Base Sequence', 'Blotting, Northern', 'DNA Nucleotidyltransferases', 'Female', 'Integrases', 'Kidney', 'Killer Cells, Natural', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred CBA', 'Molecular Sequence Data', 'RNA, Messenger', 'Receptors, Antigen, T-Cell, alpha-beta', 'Recombinases', 'T-Lymphocytes', ... | 1,530,865 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D08.811.913.696.445.308'], ['D08.811.739.500'], ['A05.810.453'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Suppression effects of human recombinant tissue inhibitor of metalloproteinases-1(TIMP-1) on tumor proliferation using in vivo treatment model of well-differentiated colon cancer cell line, HT29. | To investigate the suppressive effect of human recombinant TIMP-1 (rh-TIMP-1) on tumor proliferation using an in vivo xenograft system, HT29 was suspended in 0.1 ml phosphate buffered saline (PBS) and then subcutaneously injected in the back of female mice (BALB/C nu/nu). The mice were divided into 2 groups an and the ... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Colonic Neoplasms', 'Female', 'Gene Expression Regulation, Neoplastic', 'HT29 Cells', 'Humans', 'Metalloproteases', 'Mice', 'Mice, Nude', 'Recombinant Proteins', 'Tissue Inhibitor of Metalloproteinase-1'] | 17,072,372 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['G05.308.370'], ['A11.251.210.190.475', 'A11.251.860.180.475', 'A11.436.365'], ['B01.050.150.900.649.313.988.40... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequence-specific polypeptoids: a diverse family of heteropolymers with stable secondary structure. | We have synthesized and characterized a family of structured oligo-N-substituted-glycines (peptoids) up to 36 residues in length by using an efficient solid-phase protocol to incorporate chemically diverse side chains in a sequence-specific fashion. We investigated polypeptoids containing side chains with a chiral cent... | ['Circular Dichroism', 'Computer Simulation', 'Glycine', 'Models, Molecular', 'Peptides', 'Peptoids', 'Protein Denaturation', 'Protein Structure, Secondary', 'Structure-Activity Relationship', 'Thermodynamics'] | 9,539,732 | [['E05.196.867.151'], ['L01.224.160'], ['D12.125.481'], ['E05.599.595'], ['D12.644'], ['D12.644.679'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G02.111.570.820.709.600'], ['G02.111.830', 'G07.690.773.997'], ['G01.906']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of dietary fat supplementation on the composition and positional distribution of fatty acids in ruminant and porcine glycerides. | Dietary fats which were protected from ruminal metabolism were fed to ruminants, and the constituent fatty acids subsequently appeared in the glycerides of tissues and secretory products. These dietary fat induced alterations in tissue lipid composition were particularly apparent when the fat source was enriched with l... | ['Adipose Tissue', 'Animals', 'Bile', 'Cattle', 'Dietary Fats', 'Fatty Acids', 'Female', 'Glycerides', 'Goats', 'Liver', 'Lymph', 'Milk', 'Oils', 'Organ Specificity', 'Phospholipids', 'Plants', 'Sheep', 'Species Specificity'] | 1,250,066 | [['A10.165.114'], ['B01.050'], ['A12.200.087'], ['B01.050.150.900.649.313.500.380.271'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D10.251'], ['D10.351'], ['B01.050.150.900.649.313.500.380.513'], ['A03.620'], ['A12.207.270.606', 'A15.382.520.150'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.3... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A pilot study of the mental workload of objective structured clinical examination examiners. | CONTEXT: Mental workload is a concept used in many industries to investigate operator performance, but it has only recently been used in the educational setting. It has been suggested that excessive mental workload in assessors may impair the validity of objective structured clinical examination (OSCE)-type assessments... | ['Clinical Competence', 'Educational Measurement', 'Humans', 'Pilot Projects', 'Reaction Time', 'Reproducibility of Results', 'Research Design', 'Self Report', 'Statistics, Nonparametric', 'Task Performance and Analysis', 'Teaching', 'Workload'] | 24,528,461 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
A semi-analytical solution for simulating contaminant transport subject to chain-decay reactions. | We present a set of new, semi-analytical solutions to simulate three-dimensional contaminant transport subject to first-order chain-decay reactions. The aquifer is assumed to be areally semi-infinite, but finite in thickness. The analytical solution can treat the transformation of contaminants into daughter products, l... | ['Groundwater', 'Models, Theoretical', 'Uranium', 'Water Pollutants, Chemical', 'Water Pollution'] | 23,153,684 | [['G01.311.355'], ['E05.599'], ['D01.268.271.100.950', 'D01.268.556.900', 'D01.496.749.305.100.950', 'D01.552.020.940', 'D01.552.544.900'], ['D27.888.284.903.655'], ['N06.850.460.790']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Early postoperative enteral nutrition improves gut oxygenation and reduces costs compared with total parenteral nutrition. | OBJECTIVE: To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition.DESIGN: Prospective, randomized clinical trial.SETTING: Department of surgery in a university hospital.PATIENTS: Two hundred and fifty-seven patients with cancer of the stomach (n = 121... | ['Aged', 'Energy Intake', 'Enteral Nutrition', 'Esophageal Neoplasms', 'Female', 'Food, Formulated', 'Hospital Costs', 'Hospital Mortality', 'Humans', 'Hyperglycemia', 'Infections', 'Inflammation', 'Intestinal Mucosa', 'Length of Stay', 'Male', 'Middle Aged', 'Morbidity', 'Nutrition Assessment', 'Oxygen', 'Pancreatic N... | 11,246,300 | [['M01.060.116.100'], ['G07.203.650.240.340'], ['E02.421.360', 'E02.642.500.360'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['G07.203.300.525.350', 'J02.500.525.350'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['E05.318.308.985.550.400', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Elemental metals for environmental remediation: learning from cementation process. | The further development of Fe(0)-based remediation technology depends on the profound understanding of the mechanisms involved in the process of aqueous contaminant removal. The view that adsorption and co-precipitation are the fundamental contaminant removal mechanisms is currently facing a harsh scepticism. Results f... | ['Adsorption', 'Aluminum', 'Chemical Precipitation', 'Electrochemical Techniques', 'Environmental Restoration and Remediation', 'Iron', 'Metals', 'Water Pollutants, Chemical', 'Zinc'] | 20,554,389 | [['G01.030', 'G02.020'], ['D01.268.557.050', 'D01.552.547.050'], ['E05.196.150', 'G02.159'], ['E05.301'], ['N06.230.080.600', 'N06.850.460.375'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.552'], ['D27.888.284.903.655'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vaccination with SPf66, a chemically synthesised vaccine, against Plasmodium falciparum malaria in Colombia. | Preclinical and clinical studies have established the safety and immunogenicity of the chemically synthesised SPf66 malaria vaccine. The present study is a phase III randomised, double-blind, placebo-controlled, efficacy trial completed in La Tola, Colombia. 1548 volunteers over one year of age received three doses of ... | ['Adolescent', 'Adult', 'Animals', 'Child', 'Child, Preschool', 'Colombia', 'Double-Blind Method', 'Female', 'Humans', 'Incidence', 'Infant', 'Malaria, Falciparum', 'Male', 'Middle Aged', 'Patient Compliance', 'Plasmodium falciparum', 'Protozoan Proteins', 'Protozoan Vaccines', 'Recombinant Proteins', 'Treatment Outcom... | 8,095,622 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.757.284'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.37... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Impact of race on infrainguinal angioplasty and stenting. | BACKGROUND: Over the last decade, catheter-based interventions on lower extremity arteries have been used with increasing frequency. However, the effect of racial background on the outcome of lower extremity endovascular interventions for peripheral arterial disease is unknown. The purpose of this study was to determin... | ['African Americans', 'Aged', 'Angioplasty, Balloon', 'Arterial Occlusive Diseases', 'Asian Americans', 'Ethnic Groups', 'European Continental Ancestry Group', 'Female', 'Femoral Artery', 'Hispanic Americans', 'Humans', 'Kaplan-Meier Estimate', 'Los Angeles', 'Lower Extremity', 'Male', 'Popliteal Artery', 'Proportional... | 21,315,232 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137'], ['M01.686.508.200.100', 'M01.686.754.225'], ['M01.686.754', 'N01.224.317'], ['M01.686.508.400'], ['A07.015.114.351'], ['M01.686.754.441'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical analysis of 14 cases of epithelioid sarcoma]. | BACKGROUND & OBJECTIVE: Epithelioid sarcoma is a rare soft tissue sarcoma with a high propensity for aggressiveness, regional nodal spread, and distant metastases. This study was to investigate the clinical features, diagnosis, treatment, and prognosis of epithelioid sarcoma.METHODS: The clinical data of 14 patients wi... | ['Adult', 'Amputation', 'Chemotherapy, Adjuvant', 'Extremities', 'Female', 'Follow-Up Studies', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Radiotherapy, Adjuvant', 'Sarcoma', 'Soft Tissue Neoplasms', 'Survival Rate'] | 17,626,760 | [['M01.060.116'], ['E04.555.080'], ['E02.186.170', 'E02.319.170'], ['A01.378'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['C04.697.655', 'C23.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ozone inactivation of Cryptosporidium parvum in demand-free phosphate buffer determined by in vitro excystation and animal infectivity. | Inactivation of Cryptosporidium parvum oocysts by ozone was performed in ozone demand-free 0.05 M phosphate buffer (pH 6.9) in bench-scale batch reactors at 7 and 22 degrees C. Ozone was added to each trial from a concentrated stock solution for contact times ranging from 5 to 15 min. The viability of the control and t... | ['Animals', 'Cryptosporidium parvum', 'Mice', 'Models, Biological', 'Ozone'] | 8,285,711 | [['B01.050'], ['B01.043.075.189.250.150.160.170'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['D01.362.670.600']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Olive Mild Mosaic Virus Coat Protein and P6 Are Suppressors of RNA Silencing, and Their Silencing Confers Resistance against OMMV. | RNA silencing is an important defense mechanism in plants, yet several plant viruses encode proteins that suppress this mechanism. In this study, the genome of the Olive mild mosaic virus (OMMV) was screened for silencing suppressors. The full OMMV cDNA and 5 OMMV open reading frames (ORFs) were cloned into the Gateway... | ['Agrobacterium tumefaciens', 'Cloning, Molecular', 'Disease Resistance', 'Genetic Vectors', 'Genome, Viral', 'Plant Diseases', 'Plants, Genetically Modified', 'RNA Interference', 'Tobacco', 'Tombusviridae', 'Viral Proteins'] | 30,096,871 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['E05.393.220'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['G05.360.337'], ['G05.360.340.358.840'], ['G15.610'], ['B01.650.520', 'B05.620.600'], ['G05.308.203.374.790'], ['B01.650.940.800.575.912.250.908.500.900'], ['B04.715.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The squalestatins: inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C3-modified analogues. | Squalestatin analogues modified at C3 were prepared and evaluated for their ability to inhibit rat liver microsomal squalene synthase in vitro. While the 4,6-dimethyloctenoate ester group at C6 was maintained, a number of modifications to the C3 carboxylic acid were well tolerated. However, in the absence of the C6 est... | ['Animals', 'Anticholesteremic Agents', 'Bridged Bicyclo Compounds, Heterocyclic', 'Callithrix', 'Cholesterol', 'Enzyme Inhibitors', 'Esters', 'Farnesyl-Diphosphate Farnesyltransferase', 'Microsomes, Liver', 'Molecular Structure', 'Rats', 'Tricarboxylic Acids'] | 8,691,471 | [['B01.050'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D03.605.084'], ['B01.050.150.900.649.313.988.400.600.150.150.114'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D27.505.519.389'], ['D02.241.400'], ['D08.811.913.225.431'], ['A11.284.835.540.541'], ['G02.111.570', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral effects of N-cyanomethylmethamphetamine, a product derived from smoking methamphetamine with tobacco, in mice and rats. | The stimulant effects of N-cyanomethylmethamphetamine (CMMA), a product derived from smoking methamphetamine (MA) mixed in tobacco, were studied by observing stereotyped behavior and measuring spontaneous motor activity in mice and rats over 180 min CMMA. 1.3 and 10 mg/kg IP, elicited strong stimulant-like effects whic... | ['Amphetamines', 'Animals', 'Central Nervous System Stimulants', 'Drug Evaluation, Preclinical', 'Male', 'Methamphetamine', 'Mice', 'Mice, Inbred ICR', 'Motor Activity', 'Rats', 'Rats, Wistar', 'Smoking', 'Species Specificity', 'Stereotyped Behavior'] | 9,164,568 | [['D02.092.471.683.152'], ['B01.050'], ['D27.505.696.282', 'D27.505.954.427.220'], ['E05.290.750', 'E05.337.550'], ['D02.092.471.683.152.619'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum manganese superoxide dismutase (MnSOD) and histological virulence of ovarian cancer. | The serum level of a scavenging enzyme, manganese superoxide dismutase (MnSOD), was examined in 78 patients with ovarian cancer. Tumors included 27 stage I, 6 stage II, 37 stage III and 8 stage IV diseases. They were classified as 43 serous, 18 mucinous, 10 clear cell and 7 endometrioid neoplasms, and grouped into 25 g... | ['Adenocarcinoma', 'Female', 'Humans', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Superoxide Dismutase'] | 8,135,676 | [['C04.557.470.200.025'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['D08.811.682.881']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical efficacy and bacteriological studies of clarithromycin and cefdinir against group A beta-hemolytic streptococcal tonsillopharyngitis]. | The clinical efficacy and safety of clarithromycin (CAM) and cefdinir (CFDN) were evaluated in 65 pediatric outpatients with group A beta-hemolytic streptococcal tonsillopharyngitis. Treatment was "effective" or better in 26 (78.8%) children receiving CAM and in 27 (87.1%) receiving CFDN based on antigen clearance and ... | ['Administration, Oral', 'Anti-Bacterial Agents', 'Cefdinir', 'Cephalosporins', 'Child', 'Child, Preschool', 'Clarithromycin', 'Drug Administration Schedule', 'Drug Evaluation', 'Humans', 'Pharyngitis', 'Streptococcal Infections', 'Streptococcus pyogenes', 'Tonsillitis'] | 14,567,252 | [['E02.319.267.100'], ['D27.505.954.122.085'], ['D02.065.589.099.249.169', 'D02.886.665.074.169', 'D03.633.100.300.249.169'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['M01.060.406'], ['M01.060.406.448'], ['D02.540.576.500.992.100'], ['E02.319.283'], ['E05.290.625', 'E05.337.425'], ['B01.050.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vitro translation of cytosolic and peroxisomal epoxide hydrolase and catalase on liver polyribosomes from untreated and clofibrate-treated C57B1/6 mice. | Free and membrane-bound polyribosomes were isolated from the livers of untreated and clofibrate-treated male C57B1/6 mice. The in vitro translation products were investigated in a rabbit reticulocyte cell-free system by immunoprecipitation of cytosolic epoxide hydrolase, catalase and albumin. The soluble forms of epoxi... | ['Animals', 'Catalase', 'Clofibrate', 'Cytosol', 'Enzyme Activation', 'Epoxide Hydrolases', 'Gene Expression Regulation', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Microbodies', 'Polyribosomes', 'Protein Biosynthesis'] | 2,721,690 | [['B01.050'], ['D08.811.682.732.332'], ['D02.241.081.114.968.500.500.195', 'D02.355.726.305.500.195', 'D02.455.426.559.389.657.654.305.500.195'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G02.111.263', 'G03.328'], ['D08.811.277.340'], ['G05.308'], ['A03.620'], ['B01.050.150.900.649.313.99... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gender differences in clinical correlates of suicidality among young adults. | Gender differences were examined in risk factors for suicidality among young adult friends of suicide victims. Data were derived from a follow-up community survey of 76 members of the social network of 23 consecutive adolescent suicide victims 6 years after the friend's death. The Beck-Kovacs Scale for Suicidal Ideatio... | ['Adolescent', 'Adult', 'Age Factors', 'Aggression', 'Anxiety Disorders', 'Comorbidity', 'Data Collection', 'Depressive Disorder', 'Female', 'Follow-Up Studies', 'Health Status', 'Humans', 'Life Change Events', 'Male', 'Outcome Assessment, Health Care', 'Personality Inventory', 'Psychology, Adolescent', 'Regression Ana... | 9,952,250 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.126.125', 'F01.145.813.045'], ['F03.080'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F03.600.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.8... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Cortical-Bone Fragility--Insights from sFRP4 Deficiency in Pyle's Disease. | BACKGROUND: Cortical-bone fragility is a common feature in osteoporosis that is linked to nonvertebral fractures. Regulation of cortical-bone homeostasis has proved elusive. The study of genetic disorders of the skeleton can yield insights that fuel experimental therapeutic approaches to the treatment of rare disorders... | ['Adolescent', 'Animals', 'Biomarkers', 'Bone Density', 'Bone Morphogenetic Proteins', 'Bone Remodeling', 'Bone and Bones', 'Child, Preschool', 'Disease Models, Animal', 'Female', 'Gene Deletion', 'Homeostasis', 'Humans', 'Male', 'Mice', 'Mice, Knockout', 'Middle Aged', 'Osteochondrodysplasias', 'Proto-Oncogene Protein... | 27,355,534 | [['M01.060.057'], ['B01.050'], ['D23.101'], ['G11.427.100'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['G11.427.213', 'G16.762.150'], ['A02.835.232', 'A10.165.265'], ['M01.060.406.448'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G07.410'], ['B... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cell cycle arrest and apoptosis induction by an anticancer chalcone epoxide. | Safe and effective chemotherapeutic agents for the treatment of pancreatic cancer remain elusive. We found that chalcone epoxides (1,3-diaryl-2,3-epoxypropanones) inhibited growth in two pancreatic cancer cell lines, BxPC-3 and MIA PaCa-2. Three compounds were active, with GI(50) values of 5.6 to 15.8 microM. Compound ... | ['Antineoplastic Agents', 'Apoptosis', 'Cell Cycle', 'Cell Proliferation', 'Chalcones', 'Humans', 'Microtubules', 'Pancreatic Neoplasms', 'Tumor Cells, Cultured'] | 20,726,006 | [['D27.505.954.248'], ['G04.146.954.035'], ['G04.144'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.522.818.222', 'D03.383.663.283.266.450.221', 'D03.633.100.150.266.450.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.750.602'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The absorption of immunoglobulin from colostrum by bottle-fed lambs. | Factors affecting the absorption of immunoglobulin from colostrum by new born lambs were studied. Merino, Scottish Blackface, Cheviot, Southdown, Border Leicester, Finnish Landrace and Finnish Landrace x Dorset Horn lambs were removed from their mothers before sucking and bottle-fed with measured amounts of colostrum, ... | ['Absorption', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Animals, Newborn', 'Body Weight', 'Bottle Feeding', 'Colostrum', 'Female', 'Immunoglobulin G', 'Immunoglobulins', 'Male', 'Sheep'] | 547,826 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A physiological pharmacokinetic model describing the disposition of lycopene in healthy men. | A physiological pharmacokinetic model was developed to describe the disposition of lycopene, delivered as a tomato beverage formulation in five graded doses (10, 30, 60, 90, or 120 mg), for a phase I study in healthy male subjects (five per dose). Blood was collected before dose administration (0 h) and at scheduled in... | ['Adult', 'Anticarcinogenic Agents', 'Antioxidants', 'Beverages', 'Carotenoids', 'Chromatography, High Pressure Liquid', 'Diet', 'Dose-Response Relationship, Drug', 'Humans', 'Lipids', 'Liver', 'Lycopene', 'Lycopersicon esculentum', 'Male', 'Middle Aged', 'Olive Oil', 'Plant Oils', 'Tissue Distribution', 'Vitamins'] | 12,867,539 | [['M01.060.116'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.100', 'J02.200'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['E05.196.181.400.300'], ['G07.203.650.240'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Attentional and eye tracking deficits correlate with negative symptoms in schizophrenia. | Thirty patients with a DSM-III-R diagnosis of schizophrenia were assessed for severity of schizophrenic symptoms using the Brief Psychiatric Rating Scale (BPRS) and were tested on a Continuous Performance Test (CPT) and a smooth pursuit eye tracking task. Negative symptoms were significantly correlated with eye trackin... | ['Adult', 'Attention', 'Eye', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Schizophrenia', 'Wechsler Scales'] | 9,323,344 | [['M01.060.116'], ['F02.830.104.214'], ['A01.456.505.420', 'A09.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513.653'], ['F03.700.750'], ['F04.711.141.493.822']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gerbils of a seizure-sensitive strain have a mitochondrial inner membrane protein with different isoelectric points from those of a seizure-resistant strain. | The distribution of proteins in the cerebral cortex of a seizure-sensitive (SS) strain of gerbil and its seizure-resistant (SR) counterpart was profiled using two-dimensional gel electrophoresis. A series of proteins of similar molecular weight (around 83 kDa) showed small but consistent differences in their isoelectri... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cerebral Cortex', 'Chromatography, High Pressure Liquid', 'DNA Primers', 'DNA, Complementary', 'Disease Models, Animal', 'Disease Susceptibility', 'Electrophoresis, Gel, Two-Dimensional', 'Gerbillinae', 'Humans', 'Immunity, Innate', 'Intracellular Membranes', 'Membra... | 12,481,273 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211.200.885.287.500'], ['E05.196.181.400.300'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['C22.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Production and excretion of dopamine by the isolated perfused rat kidney. | Renal catecholamine concentrations and urinary dopamine excretion from the isolated perfused kidney were measured in intact and peripherally sympathectomized rats. Urinary dopamine excretion was not diminished by sympathectomy, was increased by l-dopa (but not tyrosine or dopamine 4-O-sulphate) in the perfusate and was... | ['Animals', 'Carbidopa', 'Catecholamines', 'Dopamine', 'Hydroxydopamines', 'Kidney', 'Kidney Function Tests', 'Rats', 'Tyrosine'] | 4,023,392 | [['B01.050'], ['D02.092.311.200.538.200', 'D02.442.200', 'D02.455.426.559.389.657.166.175.200.538.200'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.092.311.342.478', 'D02.455.426.559.389.657.166.175.342.478'], ['A05.810.45... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Visual stability in diabetic retinopathy treated by panretinal laser photocoagulation]. | PURPOSE: To evaluate the effect of laser treatment in the visual acuity caused by advanced diabetic retinopathy without visual complaints.METHODS: A descriptive observational study was developed in advanced diabetic retinopathy patients not presenting visual complaints. The patients were submitted to argon laser panret... | ['Aged', 'Diabetes Complications', 'Diabetic Retinopathy', 'Female', 'Follow-Up Studies', 'Humans', 'Laser Coagulation', 'Male', 'Middle Aged', 'Retina', 'Severity of Illness Index', 'Statistics, Nonparametric', 'Treatment Outcome', 'Visual Acuity'] | 17,684,618 | [['M01.060.116.100'], ['C19.246.099'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.520.745.410', 'E02.594.530', 'E04.014.520.530', 'E04.350.750.410', 'E04.540.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The influence of HER2 genotypes as molecular markers on breast cancer outcome. | Alterations of the human epidermal growth factor receptor 2 (HER2) protooncogene have been implicated in the carcinogenesis and prognosis of breast cancer. A polymorphism has been identified at codon 655 (ATC/isoleucine to GTC/valine [I655V]) in the transmembrane domain-coding region of this gene, which may be associat... | ['Adult', 'Breast', 'Breast Neoplasms', 'Case-Control Studies', 'DNA, Neoplasm', 'Female', 'Genotype', 'Humans', 'Middle Aged', 'Phenotype', 'Polymorphism, Genetic', 'Receptor, ErbB-2'] | 18,721,072 | [['M01.060.116'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.444.308.425'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.695'], ['G05.365.795'], ['D08.811.913.696.620.682.725.400.009.40... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional bacteria and process metabolism of the Denitrifying Sulfur conversion-associated Enhanced Biological Phosphorus Removal (DS-EBPR) system: An investigation by operating the system from deterioration to restoration. | A sulfur conversion-associated Enhanced Biological Phosphorus (P) Removal (EBPR) system is being developed to cater for the increasing needs to treat saline/brackish wastewater resulting from seawater intrusion into groundwater and sewers and frequent use of sulfate coagulants during drinking water treatment, as well a... | ['Bacteria', 'Bioreactors', 'Denitrification', 'Phosphorus', 'Sewage', 'Sulfur', 'Waste Disposal, Fluid'] | 27,010,789 | [['B03'], ['E07.115', 'J01.897.120.115'], ['G02.111.587.250', 'G02.607.560.250', 'G16.500.768.249'], ['D01.268.666'], ['D20.944.932.500'], ['D01.268.185.900'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Psoralen-cross-linking study of the organization of intracellular adenovirus nucleoprotein complexes. | We used the psoralen-cross-linking technique to investigate the structures of adenovirus nucleoprotein complexes during infection. At late times after infection, three types of psoralen cross-linking patterns were observed. A high cross-linking pattern (type I), with about one cross-link in every 10 to 17 base pairs, w... | ['Adenoviruses, Human', 'Cross-Linking Reagents', 'DNA Replication', 'DNA Restriction Enzymes', 'DNA, Viral', 'Deoxyribonucleases, Type II Site-Specific', 'Electrophoresis, Agar Gel', 'Furocoumarins', 'HeLa Cells', 'Humans', 'Microscopy, Electron', 'Nucleoproteins', 'Recombination, Genetic', 'Templates, Genetic', 'Tran... | 2,831,383 | [['B04.280.030.500.350'], ['D27.720.470.410.210'], ['G02.111.225', 'G05.226'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.568'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['E05.196.401.153', 'E05.301.300.100'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute peripheral neuropathy due to hereditary coproporphyria. | A 23-year-old man with epilepsy and a past history of abdominal pain and ileus, developed hypertension and arm and bulbar weakness when valproic acid and carbamazepine were reinitiated. Electrophysiologic studies demonstrated a peripheral neuropathy with features of axonal degeneration and demyelination. Axonal degener... | ['Acute Disease', 'Adult', 'Electrodiagnosis', 'Humans', 'Male', 'Peripheral Nervous System Diseases', 'Porphyrias, Hepatic', 'Sural Nerve'] | 8,008,008 | [['C23.550.291.125'], ['M01.060.116'], ['E01.370.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829'], ['C06.552.830', 'C16.320.850.742', 'C17.800.827.742', 'C18.452.811.400'], ['A08.800.800.720.450.760.820.820']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluating the medication process in the context of CPOE use: the significance of working around the system. | OBJECTIVE: To evaluate the problems experienced after implementing a computerized physician order entry (CPOE) system, their possible root causes, and the responses of providers in order to incorporate the system into daily workflow.METHODS: A qualitative study in the medication-use process after implementation of a CP... | ['Drug Therapy', 'Medical Order Entry Systems', 'Netherlands'] | 21,555,237 | [['E02.319'], ['L01.313.500.750.300.695.600', 'N04.452.442.452.452.500', 'N04.452.515.360.500', 'N04.452.859.564.650.500'], ['Z01.542.651']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Are the pure in situ breast ductal carcinomas and those associated with invasive carcinoma the same? | It has been reported that pure ductal carcinoma in situ of the breast has morphologic differences from the in situ component of the invasive ductal carcinoma, as well estrogen and progesterone receptors expression according to their cytokeratin expression. However, there is no data comparing other tumor markers without... | ['Adult', 'Aged', 'Antigens, Neoplasm', 'Biomarkers, Tumor', 'Carcinoma, Ductal, Breast', 'Diagnosis, Differential', 'Female', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Middle Aged', 'Neoplasm Invasiveness', 'Receptor, ErbB-2', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Tumor Suppressor Protein p53', ... | 19,568,168 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['D23.101.140'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Linear acral pseudolymphomatous angiokeratoma of children with associated nail dystrophy. | Acral pseudolymphomatous angiokeratoma of children (APACHE) is a rare entity that typically occurs on the extremities of young females. Although linear arrangement of cutaneous lesions has been rarely reported, accompanying nail dystrophy has not been linked with this condition to our knowledge. We describe a case of l... | ['Angiokeratoma', 'Biopsy, Needle', 'Child', 'Female', 'Fingers', 'Humans', 'Immunohistochemistry', 'Nail Diseases', 'Prognosis', 'Pseudolymphoma', 'Rare Diseases', 'Skin Neoplasms'] | 26,436,972 | [['C04.557.645.115'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['M01.060.406'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Speciation despite globally overlapping distributions in Penicillium chrysogenum: the population genetics of Alexander Fleming's lucky fungus. | Eighty years ago, Alexander Fleming described the antibiotic effects of a fungus that had contaminated his bacterial culture, kick starting the antimicrobial revolution. The fungus was later ascribed to a putatively globally distributed asexual species, Penicillium chrysogenum. Recently, the species has been shown to b... | ['Genes, Mating Type, Fungal', 'Genetic Speciation', 'Genetics, Population', 'Humans', 'Molecular Sequence Data', 'Penicillium chrysogenum', 'Phylogeny'] | 21,951,491 | [['G05.360.340.024.340.364.500.089', 'G05.360.340.358.024.500.089', 'G05.360.340.358.365.500.089'], ['G05.045.350', 'G16.075.350'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['B01.300.381.662.592'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Activation of the kallikrein-kinin system in premature infants with respiratory distress syndrome (RDS). | Plasma prekallikrein levels, kallikrein activity and antikallikrein levels were investigated in nine premature infants with respiratory distress syndrome (RDS) and six premature infants without. Plasma prekallikrein and kallikrein were determined with a chromogenic substrate measuring amidolytic activity. Antikallikrei... | ['Blood Gas Analysis', 'Blood Proteins', 'Humans', 'Infant, Newborn', 'Kallikreins', 'Kinins', 'Prekallikrein', 'Respiratory Distress Syndrome, Newborn'] | 6,925,441 | [['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['D12.776.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.959.350.442', 'D12.776.124.125.597', 'D23.119.597'], ['D12.644.276.812', 'D12.776.467.812', 'D23.469.050.375... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk factors associated with sexually transmitted infections among HIV infected men who have sex with men. | To investigate the factors associated with sexually transmitted infection and Human Immunodeficiency Virus (STI-HIV) co-infection among men who have sex with men (MSM). A total of 357 HIV-infected participants (84 STI-HIV co-infection and 273 HIV infections only) were recruited from Jiangsu, China. Logistic regression ... | ['Adult', 'China', 'Coinfection', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Male', 'Risk Factors', 'Sexual Behavior', 'Sexually Transmitted Diseases'] | 28,158,317 | [['M01.060.116'], ['Z01.252.474.164'], ['C01.218'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.20... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Behavioral treatment of chronic pain: the spouse as a discriminative cue for pain behavior. | Twenty married chronic pain patients (pain duration > 8 mo.) consecutively admitted to a pain management program were administered a taped structured interview designed to elucidate the responses of their spouses to pain behavior. Additionally, patients were required to report their pain levels in two different observa... | ['Behavior Therapy', 'Chronic Disease', 'Cues', 'Family', 'Female', 'Humans', 'Male', 'Pain', 'Pain Management', 'Prejudice'] | 7,454,386 | [['F04.754.137'], ['C23.550.291.500'], ['F02.463.425.234'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.745', 'N04.590.607.500'], ['F01.145.813.550', 'F01.829.595']] | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Remediation: a necessary function for employers to correct incompetence regarding clinical professional registered nurse practice. | Remediation for the professional licensed registered nurse is a topic sparsely written about in the nursing literature. The provision of remediation, however, is a common tool used to address registered nurse practice issues. This article seeks to describe the various stakeholders' roles in remediation and recommends t... | ['Clinical Competence', 'Decision Making, Organizational', 'Employee Discipline', 'Humans', 'Inservice Training', 'Nursing Staff, Hospital', 'Problem Solving', 'Quality of Health Care'] | 22,617,556 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N04.452.190'], ['N04.452.677.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['F02.463.425.725', 'F02.463.785.810'], ['N04.761', 'N05.715']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Clinicopathological and immunohistochemical characteristics of papillary renal cell carcinoma with emphasis on subtyping. | Papillary renal cell carcinoma (PRCC), a morphologically and genetically distinct subtype of RCC, is morphologically separated into 2 subtypes for therapeutic and prognostic purposes. Type 2 tumors are generally believed to have a poorer prognosis than type 1 tumors. In spite of multiple studies, many clinicopathologic... | ['Adult', 'Biomarkers, Tumor', 'Carcinoma, Papillary', 'Carcinoma, Renal Cell', 'Female', 'Humans', 'Immunohistochemistry', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Prognosis', 'Tissue Array Analysis'] | 26,239,624 | [['M01.060.116'], ['D23.101.140'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
A Novel Method in the Stratification of Post-Myocardial-Infarction Patients Based on Pathophysiology. | OBJECTIVES: We proposed that the severity of ST-segment elevation myocardial infarction (STEMI) could be classified based on pathophysiological changes.METHODS: First-STEMI patients were classified within hospitalization. Grade 0: no detectable myocardial necrosis; Grade 1: myocardial necrosis without functional and mo... | ['Aged', 'Comorbidity', 'Disease Progression', 'Echocardiography', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Mitral Valve Insufficiency', 'Myocardial Infarction', 'Prognosis', 'Risk Factors', 'Severity of Illness Index', 'Time Factors', 'Ventri... | 26,090,807 | [['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.550.291.656'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Application of uncertainty and sensitivity analysis in river basin management. | Considering uncertainty in the decision-making process in river basin management is important because uncertainty is regarded as one of the main obstacles to sound decision-making. In case of high uncertainty, the risks of making a wrong decision could be quite high, which may have severe consequences. This paper appli... | ['Conservation of Natural Resources', 'Disasters', 'Models, Theoretical', 'Risk Assessment', 'Rivers', 'Uncertainty', 'Water Supply'] | 16,532,734 | [['J01.256', 'N06.230.080'], ['N06.230.100'], ['E05.599'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.715.36... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Evaluation of noninvasive diagnostic criteria for hepatocellular carcinoma on pretransplant MRI (2010): correlation between MR imaging features and histological features on liver specimen]. | PURPOSE: To validate the 2010 diagnostic criteria from the American Association for the Study of Liver Diseases (AASLD) for hepatocellular carcinoma (HCC) on MRI using the surgical liver specimen as a gold standard.PATIENTS AND METHODS: A total of 21 liver transplant recipients were retrospectively included. Each under... | ['Aged', 'Algorithms', 'Carcinoma, Hepatocellular', 'Cell Transformation, Neoplastic', 'Contrast Media', 'Female', 'France', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Liver Neoplasms', 'Liver Transplantation', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Re... | 21,819,911 | [['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D27.505.259.500', 'D27.720.259'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Prevalence of hepatitis C virus antibodies in primary glomerulonephritis in Brazil. | The association between hepatitis B virus and membranous glomerulonephritis and membranoproliferative glomerulonephritis (MPGN) was first described in 1971. Recently, a similar association between hepatitis C virus (HCV) and glomerulonephritis (GN) has been reported. We investigated the prevalence of hepatitis C serum ... | ['Adolescent', 'Adult', 'Aged', 'Brazil', 'Female', 'Glomerulonephritis', 'Glomerulonephritis, Membranoproliferative', 'Hepacivirus', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Male', 'Middle Aged', 'RNA, Viral', 'Seroepidemiologic Studies'] | 9,845,823 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.107.757.176'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['C12.777.419.570.363.615', 'C13.351.968.419.570.363.615', 'C20.425'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
On the Emergence of Cryptococcus gattii in the Pacific Northwest: Ballast Tanks, Tsunamis, and Black Swans. | The appearance of Cryptococcus gattii in the North American Pacific Northwest (PNW) in 1999 was an unexpected and is still an unexplained event. Recent phylogenomic analyses strongly suggest that this pathogenic fungus arrived in the PNW approximately 7 to 9 decades ago. In this paper, we theorize that the ancestors of... | ['Animals', 'Anseriformes', 'Cryptococcus gattii', 'Environmental Microbiology', 'Northwestern United States', 'Phylogeny', 'Phylogeography', 'Ships', 'Tsunamis'] | 31,575,770 | [['B01.050'], ['B01.050.150.900.248.050'], ['B01.300.381.258.300', 'B01.300.930.316.300'], ['H01.158.273.540.274', 'N06.850.425'], ['Z01.107.567.875.560'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['H01.158.273.343.335.500', 'H01.277.500.589'], ['J01.937.817'], ['G01.311.933']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Monosymptomatic presentation of type I Arnold-Chiari malformation: report of two cases. | Two cases of type I ACM are described, one of which presented with dizziness in late childhood (case 1), the other with mild intention tremor in adulthood (case 2). Cerebellar ectopia should be considered in monosymptomatic patients even in the absence of other symptoms and signs of C.N.S. dysfunction. Magnetic resonan... | ['Adolescent', 'Adult', 'Arnold-Chiari Malformation', 'Brain', 'Cerebellum', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male'] | 8,206,748 | [['M01.060.057'], ['M01.060.116'], ['C10.500.680.291', 'C16.131.666.680.291'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complications associated with the pedicled nasoseptal flap for skull base reconstruction. | OBJECTIVES/HYPOTHESIS: To analyze complications associated with nasoseptal flap elevation and reconstruction in endoscopic skull base surgery.STUDY DESIGN: Case series.METHODS: Retrospective chart review of all patients who underwent nasoseptal flap procedure in our institution between 2008 and 2013.RESULTS: A total of... | ['Adolescent', 'Adult', 'Child', 'Endoscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Nasal Cartilages', 'Nasal Septal Perforation', 'Necrosis', 'Nose Diseases', 'Postoperative Complications', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Skull Base', 'Surgical Flaps', 'Tissue... | 25,111,727 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E01.370.388.250', 'E04.502.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.165.407.550', 'A04.531.413'], ['C08.460.595', 'C09.603.588', 'C26... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Axon regrowth during development and regeneration following injury share molecular mechanisms. | BACKGROUND: The molecular mechanisms that determine axonal growth potential are poorly understood. Intrinsic growth potential decreases with age, and thus one strategy to identify molecular pathways controlling intrinsic growth potential is by studying developing young neurons. The programmed and stereotypic remodeling... | ['Animals', 'Animals, Genetically Modified', 'Axons', 'Drosophila', 'Drosophila Proteins', 'Metamorphosis, Biological', 'Monomeric GTP-Binding Proteins', 'Mushroom Bodies', 'Nerve Regeneration', 'Neuropeptides', 'Ras Homolog Enriched in Brain Protein', 'Receptors, Cytoplasmic and Nuclear', 'TOR Serine-Threonine Kinases... | 22,921,367 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G07.345.500.550'], ['D08.811.277.040.330.300.400', 'D12.644.360.525', 'D12.776.157.325.515', 'D12.776.476.525'], ['A13.6... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequence and structural analysis of BTB domain proteins. | BACKGROUND: The BTB domain (also known as the POZ domain) is a versatile protein-protein interaction motif that participates in a wide range of cellular functions, including transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting proteins for ubiquitination. Several BTB domain ... | ['Amino Acid Sequence', 'Animals', 'DNA-Binding Proteins', 'Genome', 'Models, Molecular', 'Molecular Sequence Data', 'Phylogeny', 'Protein Binding', 'Protein Folding', 'Protein Structure, Tertiary', 'Sequence Analysis, DNA', 'Sequence Analysis, Protein', 'Zinc Fingers'] | 16,207,353 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.260'], ['G05.360.340'], ['E05.599.595'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.679', 'G03.808'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.610'], ['E05.393.760.700'], ['E05.393.760.705'], ['G02.111.570.82... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor. | A cell-sensor assay for stabilization of IkappaBalpha was developed in the activated B cell-like diffuse large B-cell lymphoma cell line OCI-Ly3. This cell line expresses known nuclear factor kappaB (NFkappaB) target genes due to high constitutive activity of IkappaB kinase (IKK), which phosphorylates the protein Ikapp... | ['Biological Assay', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'Humans', 'I-kappa B Proteins', 'Luciferases', 'Lymphoma, B-Cell', 'Microscopy, Fluorescence, Multiphoton', 'NF-KappaB Inhibitor alpha', 'Neoplasm Proteins'] | 17,355,202 | [['E05.091'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.365', 'D12.776.260.420', 'D12.776.476.381', 'D12.776.930.326'], ['D08.811.682.517', 'D12.776.532.510'], ['C04.557.386.480.150', 'C15.604.515.569.480.150', 'C20.683.515.761.480.150'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CD46 expression does not overcome the intracellular block of measles virus replication in transgenic rats. | The study of measles pathogenesis and the testing of improved vaccine candidates is hampered by the lack of a small animal model which is susceptible to infection by the intranasal route. With the identification of CD46 as a measles virus (MV) receptor, it was feasible to generate transgenic rats to overcome this probl... | ['Animals', 'Animals, Genetically Modified', 'Antigens, CD', 'Cell Line', 'Disease Susceptibility', 'Down-Regulation', 'Humans', 'Lymphocytes', 'Measles', 'Measles virus', 'Membrane Cofactor Protein', 'Membrane Glycoproteins', 'Nucleocapsid', 'Organ Specificity', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Recep... | 9,311,889 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251.210'], ['C23.550.291.687', 'G07.100.250'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Radiocompetitive dosage of 25 hydroxyvitamin D and 24, 25-dihydroxyvitamin D in geriatrics. Study of seasonal variations]. | Dosages of 25 (OH) D and of 24, 25 (OH) 2 D in the plasma were done in March and October in 26 women more than 70 years old, hospitalized in a semi-chronic disease hospital of the Paris area. Eleven young adults, studied in June, served as control. There was a significant decrease of 25 (OH) D and 24,25 (OH) 2 D in old... | ['Aged', 'Dihydroxycholecalciferols', 'Female', 'Humans', 'Hydroxycholecalciferols', 'Seasons', 'Vitamin D Deficiency'] | 545,663 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low-density lipoprotein receptor genotype and response to pravastatin in children with familial hypercholesterolemia: substudy of an intima-media thickness trial. | BACKGROUND: The lipid-lowering effects of statin therapy show considerable interindividual variation in patients with familial hypercholesterolemia (FH). Whether the type of LDL receptor mutation predicts the response to statin treatment is not yet established. We analyzed the relationship between LDL receptor genotype... | ['Adolescent', 'Cardiovascular Diseases', 'Child', 'Coronary Vessels', 'Double-Blind Method', 'Female', 'Gene Deletion', 'Genotype', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Hyperlipoproteinemia Type II', 'Male', 'Placebos', 'Pravastatin', 'Receptors, LDL', 'Tunica Intima', 'Tunica Media'] | 16,286,607 | [['M01.060.057'], ['C14'], ['M01.060.406'], ['A07.015.114.269', 'A07.015.908.194'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Optimization of the Expression Conditions of CGA-N46 in Bacillus subtilis DB1342(p-3N46) by Response Surface Methodology. | CGA-N46 is a small antifungal-derived peptide and consists of the 31st-76th amino acids of the N-terminus of human chromogranin A. Polycistronic expression of recombinant CGA-N46 in Bacillus subtilis DB1342 was used to improve its production, but the yield of CGA-N46 was still low. In the present study, response surfac... | ['Antifungal Agents', 'Bacillus subtilis', 'Bacterial Proteins', 'Bioengineering', 'Biostatistics', 'Culture Media', 'Yeasts'] | 26,341,498 | [['D27.505.954.122.136'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['J01.293.069'], ['E05.318.740.237'], ['D27.720.470.305', 'E07.206'], ['B01.300.930']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The epidemiology of psychiatric disorders among women with breast cancer in South Korea: analysis of national registry data. | OBJECTIVE: Population-based data on the epidemiology of psychiatric disorders in patients with breast cancer are lacking. Because the National Health Insurance (NHI) Program in South Korea is a compulsory social insurance system covering the entire Korean population, the NHI is a good source of information for epidemio... | ['Adjustment Disorders', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Anxiety Disorders', 'Breast Neoplasms', 'Comorbidity', 'Depressive Disorder', 'Female', 'Humans', 'Incidence', 'Mental Disorders', 'Middle Aged', 'Registries', 'Republic of Korea', 'Sleep Wake Disorders', 'Young Adult'] | 24,038,620 | [['F03.950.500'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.080'], ['C04.588.180', 'C17.800.090.500'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Differential investment and costs during avian incubation determined by individual quality: an experimental study of the common eider (Somateria mollissima). | Individuals of different quality may have different investment strategies, shaping responses to experimental manipulations, thereby rendering the detection of such patterns difficult. However, previous clutch-size manipulation studies have infrequently incorporated individual differences in quality. To examine costs of... | ['Animals', 'Birds', 'Body Weight', 'Energy Metabolism', 'Litter Size', 'Nesting Behavior', 'Ovum', 'Reproduction', 'Time Factors'] | 12,641,909 | [['B01.050'], ['B01.050.150.900.248'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G03.295'], ['G08.686.530', 'G08.686.784.769.498.300'], ['F01.145.113.252.478'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['G08.686.784'], ['G01.910.857']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystal structural analysis of human serum albumin complexed with hemin and fatty acid. | BACKGROUND: Human serum albumin (HSA) is an abundant plasma protein that binds a wide variety of hydrophobic ligands including fatty acids, bilirubin, thyroxine and hemin. Although HSA-heme complexes do not bind oxygen reversibly, it may be possible to develop modified HSA proteins or heme groups that will confer this ... | ['Binding Sites', 'Crystallography, X-Ray', 'Fatty Acids', 'Hemin', 'Humans', 'Molecular Conformation', 'Protein Structure, Tertiary', 'Serum Albumin'] | 12,846,933 | [['G02.111.570.120'], ['E05.196.309.742.225'], ['D10.251'], ['D03.383.129.578.840.500.640.587.462', 'D03.633.400.909.500.640.587.462', 'D04.345.783.500.640.587.462', 'D23.767.727.640.587.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820'], ['G02.111.570.820.709.610'], ['D12.776.034.841', 'D12.77... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First record of Rhizoscyphus ericae in Southern Hemisphere's Ericaceae. | Ericoid mycorrhiza is arguably the least investigated mycorrhizal type, particularly when related to the number of potential hosts and the ecosystems they inhabit. Little is known about the global distribution of ericoid mycorrhizal (ErM) fungi, and this holds true even for the prominent ErM mycobiont Rhizoscyphus eric... | ['Argentina', 'Ericaceae', 'Glomeromycota', 'Mycorrhizae', 'Phylogeny', 'Plant Roots'] | 27,778,093 | [['Z01.107.757.077'], ['B01.650.940.800.575.912.250.341.937'], ['B01.300.320'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['A18.400']] | ['Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
DNA-damaging effects of genotoxins in mixture: nonadditive effects of aflatoxin B1 and N-acetylaminofluorene on their mutagenicity in Salmonella typhimurium. | Most animal genotoxicity studies have used exposures to single chemicals; humans, however, are potentially exposed to mixtures of genotoxins. Cancer and developmental toxicity risks associated with genotoxins in mixture are generally estimated by assuming additivity of the components. Two or more genotoxins acting sequ... | ['2-Acetylaminofluorene', 'Acetoxyacetylaminofluorene', 'Aflatoxin B1', 'Alleles', 'DNA Damage', 'Frameshift Mutation', 'Mutagenicity Tests', 'Mutagens', 'Salmonella typhimurium'] | 10,630,575 | [['D02.065.064.150', 'D02.241.081.018.110.080', 'D02.455.426.559.847.389.050', 'D04.615.389.050'], ['D02.065.064.150.100', 'D02.241.081.018.110.080.070', 'D02.455.426.559.847.389.050.060', 'D04.615.389.050.060'], ['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['G05.360.340.024.340.030'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fragile site and interstitial telomere repeat sequences at the fusion point of a de novo (Y;13) translocation. | We describe a novel fragile site in a rearranged chromosome, associated with the presence of telomeric repeat sequences at the fusion point of a translocation between chromosomes 13 and Y. The case reported in this study shows a de novo (Y;13) translocation, which appears to represent fusion of an apparently intact chr... | ['Adolescent', 'Chromosome Fragile Sites', 'Chromosome Fragility', 'Chromosomes, Human, Pair 13', 'Humans', 'In Situ Hybridization, Fluorescence', 'Male', 'Repetitive Sequences, Nucleic Acid', 'Telomere', 'Translocation, Genetic', 'Y Chromosome'] | 8,707,303 | [['M01.060.057'], ['G05.360.340.024.189.610'], ['C23.550.210.110.180', 'C23.550.362.180.180', 'G05.365.590.175.165.180', 'G05.370.180.180'], ['A11.284.187.520.300.370.375', 'G05.360.162.520.300.370.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pichia pastoris production of a prolyl 4-hydroxylase derived from Chondrosia reniformis sponge: A new biotechnological tool for the recombinant production of marine collagen. | Prolyl 4-hydroxylase (P4H) is a á2â2 tetramer catalyzing the post-translational hydroxylation of prolines in collagen. Its recombinant production is mainly pursued to realize biotechnological tools able to generate animal contaminant-free hydroxylated collagen. One promising candidate for biomedical applications is the... | ['Animals', 'Aquatic Organisms', 'Biotechnology', 'Cattle', 'Collagen', 'Pichia', 'Porifera', 'Prolyl Hydroxylases', 'Recombinant Proteins'] | 26,022,422 | [['B01.050'], ['B05.080', 'G16.500.275.725.500.650.075'], ['H01.158.550', 'J01.897.120'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.300.107.795.700', 'B01.300.930.600'], ['B01.050.500.802'], ['D08.811.682.690.416.617', 'D08.811.682.690.708.694'], ['D12.776.828']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Studies of hypertension-induced vascular hypertrophy in cultured smooth muscle cells from spontaneously hypertensive rats. | Mechanisms of vascular hypertrophy induced by hypertension were studied in cultured aortic smooth muscle cells from spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP) and compared with those from normotensive Wistar-Kyoto (WKY) rats. Fetal calf serum-stimulated ornithine decarboxylase (ODC) activity of ... | ['1-Methyl-3-isobutylxanthine', 'Adrenergic alpha-Antagonists', 'Adrenergic beta-Antagonists', 'Animals', 'Bucladesine', 'Catecholamines', 'Cells, Cultured', 'Hypertension', 'Hypertrophy', 'In Vitro Techniques', 'Isoproterenol', 'Muscle, Smooth, Vascular', 'Ornithine Decarboxylase', 'Propranolol', 'Proteins', 'Rats', '... | 6,197,373 | [['D03.633.100.759.758.824.751.500'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['D02.092.311', 'D02.455.42... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease. | We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow m... | ['Aged', 'Alzheimer Disease', 'Analysis of Variance', 'Cerebrovascular Circulation', 'Humans', 'Memory', 'Multivariate Analysis', 'Tomography, Emission-Computed, Single-Photon'] | 2,812,339 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500']... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in breast milk from two cities in Ukraine. | Substantial environmental pollution has been alleged in Ukraine, but little information is available to allow an assessment of the possible impact on humans. To help remedy this lack of information, it was of interest to investigate whether certain polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofuran... | ['Adult', 'Benzofurans', 'Female', 'Humans', 'Longitudinal Studies', 'Milk, Human', 'Polychlorinated Biphenyls', 'Polychlorinated Dibenzodioxins', 'Polymers', 'Ukraine'] | 10,522,644 | [['M01.060.116'], ['D03.633.100.127'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300.350.525.500', 'J02.200.700.500', 'J02.500.350.525.500'], ['D02.309.750', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Reversible bilateral thalamic lesions caused by primary internal cerebral vein thrombosis: a case report. | The case is reported of a patient with primary thrombosis of the internal cerebral veins who presented initially with unilateral and later developed bilateral thalamic lesions revealed by computed tomography. Magnetic resonance imaging and angiography confirmed the diagnosis. Upon anticoagulation the patient recovered ... | ['Adult', 'Female', 'Humans', 'Intracranial Embolism and Thrombosis', 'Magnetic Resonance Imaging', 'Thalamic Diseases', 'Tomography, X-Ray Computed'] | 2,614,496 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.525', 'C14.907.253.566', 'C14.907.355.590.213'], ['E01.370.350.825.500'], ['C10.228.140.915'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fibroblast growth factor 21 plays an inhibitory role in vascular calcification in vitro through OPG/RANKL system. | Vascular calcification is prevalent and associated with adverse outcome without available therapy. The benefits of fibroblast growth factor (FGF)-21 on metabolism and atherosclerosis make it a promising therapeutic agent for vascular calcification. We investigated the effects of FGF21 on vascular smooth muscle cell (VS... | ['Animals', 'Apoptosis', 'Cells, Cultured', 'Fibroblast Growth Factors', 'Muscle, Smooth, Vascular', 'Osteoprotegerin', 'RANK Ligand', 'Rats', 'Rats, Sprague-Dawley', 'Vascular Calcification'] | 28,774,557 | [['B01.050'], ['G04.146.954.035'], ['A11.251'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D12.776.543.750.705.852.760.949.249'], ['D12.644.276.374.750.562', 'D12.776.467.374.750.562', 'D23.529.374.750.562'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comprehensive assessment of cardiovascular autonomic control using photoplethysmograms recorded from the earlobe and fingers. | We compare the spectral indices of photoplethysmogram variability (PPGV) estimated using photoplethysmograms recorded from the earlobe and the middle fingers of the right and left hand and analyze their correlation with similar indices of heart rate variability (HRV) in 30 healthy subjects (26 men) aged 27 (25, 29) yea... | ['Adult', 'Autonomic Nervous System', 'Blood Pressure', 'Cardiovascular System', 'Ear', 'Female', 'Fingers', 'Heart Rate', 'Humans', 'Male', 'Photoplethysmography'] | 27,027,461 | [['M01.060.116'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['A01.456.313', 'A09.246'], ['A01.378.800.667.430'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.610.600']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions. | BACKGROUND: A sirolimus-eluting stent (Cypher, Cordis Corp) has been reported to markedly decrease restenosis in selected lesions; higher-risk lesions, including coronary bifurcations, have not been studied.METHODS AND RESULTS: This prospective study evaluated the safety and efficacy of sirolimus-eluting stents for tre... | ['Aged', 'Anticoagulants', 'Aspirin', 'Catheterization', 'Clopidogrel', 'Combined Modality Therapy', 'Comorbidity', 'Coronary Angiography', 'Coronary Restenosis', 'Coronary Stenosis', 'Coronary Thrombosis', 'Coronary Vessels', 'Death, Sudden', 'Diabetes Mellitus', 'Disease-Free Survival', 'Drug Implants', 'Female', 'Fo... | 14,981,005 | [['M01.060.116.100'], ['D27.505.954.502.119'], ['D02.455.426.559.389.657.410.595.176'], ['E02.148', 'E05.157'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['E02.186'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.370.350.130.625', 'E01.370.350.700.060.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification and expression of natriuretic peptide receptor type-A and -B mRNA in freshwater and seawater rainbow trout. | Natriuretic peptide receptors mediate the physiological response of natriuretic peptide hormones. One of the natriuretic peptide receptor types is the particulate guanylyl cyclase receptors, of which there are two identified: NPR-A and NPR-B. In fishes, these have been sequenced and characterized in eels, medaka, and d... | ['Adaptation, Physiological', 'Amino Acid Sequence', 'Animals', 'Cloning, Molecular', 'Fresh Water', 'Gene Expression Regulation', 'Guanylate Cyclase', 'Intestinal Mucosa', 'Kidney', 'Molecular Sequence Data', 'Oncorhynchus mykiss', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Receptors, Atrial Natriuretic Factor', ... | 17,109,122 | [['G07.025', 'G16.012.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.393.220'], ['G16.500.275.280', 'N06.230.232'], ['G05.308'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['A03.556.124.369', 'A10.615.550.444'], ['A05.810.453'], ['L01.453.245.667'], ['B01.050.150.900.493.817.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Relationship between the conformation of isolated rat liver mitochondria and their susceptibility to rabbit reticulocyte lipoxygenase]. | Lipoxygenase from rabbit reticulocytes cause disruption of mitochondrial membranes and peroxidation of their lipids as judged by electronmicroscopy, release of matrix enzymes and formation of malonyldialdehyde. Without substrate mitochondria become orthodox and strong lysis by lipoxygenase appears. The lysis is prevent... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Animals', 'Lipoxygenase', 'Mitochondria, Liver', 'Protein Conformation', 'Rabbits', 'Rats', 'Reticulocytes', 'Succinates'] | 413,298 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.682.690.416.583.625', 'D12.776.556.579.374.568.750'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['G02.111.570.820.709'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins. | Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is a lethal lung developmental disorder caused by heterozygous point mutations or genomic deletion copy-number variants (CNVs) of FOXF1 or its upstream enhancer involving fetal lung-expressed long noncoding RNA genes LINC01081 and LINC01082. Usi... | ['Chromosomes, Human, Pair 16', 'Comparative Genomic Hybridization', 'Female', 'Forkhead Transcription Factors', 'Genes, Lethal', 'Genome, Human', 'Genomic Imprinting', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Infant, Newborn', 'Male', 'Pedigree', 'Persistent Fetal Circulation Syndrome', 'Pulmonary Alveoli',... | 27,071,622 | [['A11.284.187.520.300.415.420', 'G05.360.162.520.300.415.420'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.360.340.024.340.350'], ['G05.360.340.350'], ['G05.308.203.500'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adaptation to a high protein, carbohydrate-free diet induces a marked reduction of fatty acid synthesis and lipogenic enzymes in rat adipose tissue that is rapidly reverted by a balanced diet. | We have previously shown that in vivo lipogenesis is markedly reduced in liver, carcass, and in 4 different depots of adipose tissue of rats adapted to a high protein, carbohydrate-free (HP) diet. In the present work, we investigate the activity of enzymes involved in lipogenesis in the epididymal adipose tissue (EPI) ... | ['Adaptation, Physiological', 'Adipose Tissue', 'Animals', 'Diet', 'Dietary Carbohydrates', 'Dietary Proteins', 'Epididymis', 'Fatty Acids', 'Insulin', 'Male', 'Rats', 'Rats, Wistar'] | 16,049,547 | [['G07.025', 'G16.012.500'], ['A10.165.114'], ['B01.050'], ['G07.203.650.240'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['A05.360.444.371'], ['D10.251'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['B01.050.150.900.649.313.992.635.505.700'],... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Caregiving for ill dependents and its association with employee health risks and productivity. | This study examined the loss of productivity and health risk status associated with employees who provide care for an ill dependent. A total of 16,651 employees (23% response rate) of a major financial services company completed a confidential Health Risk Appraisal (HRA) that included an eight-item version of the Work ... | ['Absenteeism', 'Adult', 'Age Factors', 'Caregivers', 'Case-Control Studies', 'Chronic Disease', 'Cohort Studies', 'Employee Performance Appraisal', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Occupational Health', 'Probability', 'Reference Values', 'Risk Assessment', 'Sex Factors', 'Socioeconomic ... | 15,602,179 | [['F02.784.692.107'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N04.452.677.3... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[On the alpha-fetoprotein in the diagnosis of primary liver carcinoma (author's transl)]. | The existence of Alpha-Fetoprotein was investigated in sera of 544 patients with laparoscopically and/or histologically proved chronic liver diseases and cancer of the liver. The applied methods were the double-diffusion technique (micro-Ouchterlony), the counter immunelectrophoresis and the latex agglutination test. I... | ['Adolescent', 'Adult', 'Aged', 'Counterimmunoelectrophoresis', 'Diagnosis, Differential', 'Female', 'Hemagglutination Tests', 'Hepatitis', 'Humans', 'Immunodiffusion', 'Latex Fixation Tests', 'Liver Cirrhosis', 'Liver Diseases', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Pregnancy', 'Rheumatoid ... | 62,705 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.812.735.645.350.350.150', 'E05.196.401.568.250', 'E05.200.812.735.645.350.350.150', 'E05.301.300.568.250', 'E05.478.594.760.645.350.350.150', 'E05.478.605.492.350.350.150'], ['E01.171'], ['E01.370.225.812.735.050.375', 'E05.200.812.735.050.375', 'E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Test-retest reliability of an online measure of past week alcohol consumption (the TOT-AL), and comparison with face-to-face interview. | OBJECTIVE: This paper reports on the development of a new online measure of beverage-specific past week alcohol consumption (the TOT-AL), its test-retest reliability, and comparability with the face-to-face approach of ascertaining alcohol intake.METHODS: University students participating in the reliability study compl... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Female', 'Health Promotion', 'Humans', 'Internet', 'Interviews as Topic', 'Male', 'Students', 'Time Factors', 'Young Adult'] | 19,097,705 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.848'], ['G01.910.857'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Transareolar Video-Assisted Approach to the Atrial Septal Defect and Tricuspid Valve. | Minimally invasive atrial septal defect closure and tricuspid annuloplasty in female patients are normally performed through a right submammary anterior minithoracotomy approach. However, when the aortic root is located higher, the direction of aortic cannulation becomes not ideal through the submammary incision. In su... | ['Adult', 'Cardiac Valve Annuloplasty', 'Female', 'Heart Septal Defects, Atrial', 'Humans', 'Nipples', 'Thoracic Surgery, Video-Assisted', 'Tricuspid Valve', 'Young Adult'] | 28,538,272 | [['M01.060.116'], ['E04.100.376.062', 'E04.928.220.109'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.236.500'], ['E01.370.388.250.840.830', 'E01.370.388.250.950.830', 'E04.502.250.840.830', 'E04.502.250.950.830', 'E04.928.752.830'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A new technique for low-volume continuous sampling of spent dialysate: a validation study. | The measure of hemodialysis (HD) adequacy recommended nowadays by most guidelines, Kt/V-urea, presents significant drawbacks. Direct dialysis quantification (DDQ) through total dialysate collection (TDC), considered the gold standard measure of HD adequacy, is cumbersome, which precludes its widespread use in clinical ... | ['Adult', 'Aged', 'Body Size', 'Cross-Sectional Studies', 'Dialysis Solutions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Renal Dialysis', 'Urea'] | 30,737,599 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D26.776.708.322', 'D27.505.954.578.483', 'D27.720.752.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anterior Controllable Antedisplacement Fusion as a Choice for Ossification of Posterior Longitudinal Ligament and Degenerative Kyphosis and Stenosis: Postoperative Morphology of Dura Mater and Probability Analysis of Epidural Hematoma Based on 63 Patients. | OBJECTIVE: We studied the postoperative morphology of the dura mater and analyzed the probability of epidural hematoma (EH) after anterior controllable antedisplacement and fusion (ACAF).METHODS: A total of 63 patients with a diagnosis of ossification of the posterior longitudinal ligament (OPLL) and degenerative kypho... | ['Aged', 'Constriction, Pathologic', 'Decompression, Surgical', 'Dura Mater', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Hematoma, Epidural, Spinal', 'Humans', 'Kyphosis', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Ossification of Posterior Longitudinal Ligament', 'Ret... | 30,326,317 | [['M01.060.116.100'], ['C23.300.287'], ['E04.188'], ['A08.186.566.395'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['C23.550.414.838.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.800.500'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Performance of conventional orthogonal and multiple-dipole electrocardiograms in estimating left ventricular muscle mass. | For estimating left ventricular mass (LVM), ECG criteria for left ventricular hypertrophy (LVH) were selected from conventional 12-lead ECGs, orthogonal three-lead ECGs, and multiple-dipole ECGs (MDECG). The three cardiograms were recorded in 139 patients for whom the degree of LVH was independently determined from bip... | ['Electrocardiography', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Statistics as Topic'] | 498,460 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Herpes simplex encephalitis with expanded cerebral cortex lesions on T1-weighted MRI after clinical improvement: a case report]. | We described a 58-year-old woman with herpes simplex encephalitis (HSE), who initially had fever and developed impaired consciousness. Cerebrospinal fluid (CSF) examination showed mononuclear pleocytosis and the existence of herpes simplex virus (HSV) DNA. The first T1-weighted MR image showed symmetrical swelling and ... | ['Acyclovir', 'Betamethasone', 'Cerebral Cortex', 'Encephalitis, Herpes Simplex', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged'] | 12,607,982 | [['D03.633.100.759.758.399.454.250'], ['D04.210.500.745.432.769.199', 'D04.210.500.908.093'], ['A08.186.211.200.885.287.500'], ['C01.207.245.340.350', 'C01.207.399.750.350', 'C01.925.182.525.350', 'C01.925.256.466.262', 'C10.228.140.430.520.750.350', 'C10.228.228.245.340.350', 'C10.228.228.399.750.350'], ['B01.050.150.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Comparison of eleven active components in Lonicerae Japonicae Flos,Lonicerae Japonicae Caulis and leaves of Lonicero japonica by UPLC]. | This present study aims to establish a UPLC method for simultaneously determining eleven components such as new chlorogenic acid,chlorogenic acid,caffeic acid,cryptochlorogenic acid,artichoke,isochlorogenic acid A,isochlorogenic acid B,isochlorogenic acid C,rutin,hibisin and loganin in Lonicerae Japonicae Flos,Lonicera... | ['Chromatography, High Pressure Liquid', 'Drugs, Chinese Herbal', 'Flavonoids', 'Flowers', 'Hydroxybenzoates', 'Iridoid Glycosides', 'Lonicera', 'Phytochemicals', 'Plant Leaves', 'Quality Control'] | 30,868,819 | [['E05.196.181.400.300'], ['D20.215.784.500.350', 'D26.335'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A18.024.249.500'], ['D02.241.223.100.300', 'D02.241.511.390', 'D02.455.426.559.389.127.281', 'D02.455.426.559.389.657.410'], ['D02.455.426.392.368.450.675.500.500', 'D02.455.849.575.188.500.500', 'D03... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
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