Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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New NTP analogs: the synthesis of 4'-thioUTP and 4'-thioCTP and their utility for SELEX. | The synthesis of the triphosphates of 4'-thiouridine and 4'-thiocytidine, 4'-thioUTP (7; thioUTP) and 4'-thioCTP (8; thioCTP), and their utility for SELEX (systematic evolution of ligands by exponential enrichment) is described. The new nucleoside triphosphate (NTP) analogs 7 and 8 were prepared from appropriately prot... | ['Base Sequence', 'Cytidine Triphosphate', 'DNA, Complementary', 'DNA-Directed RNA Polymerases', 'Directed Molecular Evolution', 'Humans', 'Molecular Sequence Data', 'Oligoribonucleotides', 'Ribonuclease, Pancreatic', 'Thionucleotides', 'Thrombin', 'Transcription, Genetic', 'Uridine Triphosphate', 'Viral Proteins'] | 15,914,669 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.383.742.686.246.400', 'D13.695.740.246.400', 'D13.695.827.232.400'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D08.811.913.696.445.735.270'], ['E05.393.420.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Decoding underlying brain activities in time and frequency domains through complex independent component analysis of EEG signals. | Brain activities are often investigated through Electroencephalographic (EEG) data analysis using time-domain Independent Component Analysis (ICA). Nevertheless, the instantaneous mixing model of ICA cannot properly describe spatio-temporal dynamics, such as those related to traveling waves of neural activity. In this ... | ['Algorithms', 'Brain', 'Brain Mapping', 'Electroencephalography', 'Humans', 'Pattern Recognition, Automated', 'Signal Processing, Computer-Assisted', 'Software', 'Time Factors'] | 25,570,669 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399.750'], ['L01.224.800'], ['L01.224.900'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Detection of an inhibitory cortical gradient underlying peak shift in learning: a neural basis for a false memory. | Experience often does not produce veridical memory. Understanding false attribution of events constitutes an important problem in memory research. "Peak shift" is a well-characterized, controllable phenomenon in which human and animal subjects that receive reinforcement associated with one sensory stimulus later respon... | ['Acoustic Stimulation', 'Animals', 'Association Learning', 'Auditory Cortex', 'Basal Nucleus of Meynert', 'Cholinergic Neurons', 'Conditioning, Classical', 'Discrimination Learning', 'Electric Stimulation', 'Evoked Potentials, Auditory', 'Generalization, Stimulus', 'Male', 'Mental Recall', 'Rats', 'Rats, Sprague-Dawle... | 23,063,933 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['F02.463.425.069.296'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['A08.186.211.200.885.287.249.880.100'], ['A08.675.127', 'A11.671.188'], ['F02.463.425.179.308'], ['F02.463.425.280'], ['E05.723.402'], ['G07.265.216.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical localization of substance-P, somatostatin, and methionine-enkephalin in the spinal cord and dorsal root ganglia of the North American opossum, Didelphis virginiana. | The occurrence and distribution of substance-P (SP), somatostatin (SOM), and enkephalin (ENK) were studied in the North American opossum, a generalized marsupial. Substance-P immunoreactivity was present in the tract of Lissauer as well as within lamina I, the outer part of lamina II, the lateral portion of laminae III... | ['Animals', 'Cats', 'Endorphins', 'Enkephalin, Methionine', 'Enkephalins', 'Fluorescent Antibody Technique', 'Ganglia, Spinal', 'Humans', 'Opossums', 'Somatostatin', 'Species Specificity', 'Spinal Cord', 'Substance P'] | 6,165,743 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The study of quantitative karyotypic variability by induction of chromosomal instability in cultured cells of the Indian muntjac skin fibroblasts]. | The influence of mycoplasmal contamination and somatic cell hybridization on the character of karyotypic variability in cell cultures of Indian muntjac skin fibroblasts has been investigated. Mycoplasma arginini and Acholeplasma laidlawii, used as factors inducing chromosomal instability, do not break the main regulati... | ['Acholeplasma', 'Animals', 'Cells, Cultured', 'Chromosome Aberrations', 'Fibroblasts', 'Genetic Variation', 'Karyotyping', 'Muntjacs', 'Mycoplasma'] | 10,591,121 | [['B03.440.860.074.150'], ['B01.050'], ['A11.251'], ['C23.550.210', 'G05.365.590.175'], ['A11.329.228'], ['G05.365'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['B01.050.150.900.649.313.500.380.373.322'], ['B03.440.860.580.553.553']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using Drosophila eye as a model system to characterize the function of mars gene in cell-cycle regulation. | Human hepatoma up-regulated protein (HURP), a cell-cycle regulator, is found consistently overexpressed in human hepatocellular carcinoma. At present, the function of HURP in cell-cycle regulation and carcinogenesis remains unclear. In database mining, we have identified a mars gene in Drosophila, which encodes a prote... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'Animals, Genetically Modified', 'Apoptosis', 'Blotting, Western', 'Cell Cycle', 'Cell Cycle Proteins', 'Centrosome', 'Down-Regulation', 'Drosophila', 'Drosophila Proteins', 'Eye', 'Gene Expression Regulation, Developmental', 'Genes', 'Genes, Insect', 'Immunohisto... | 15,922,738 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['D12.776.167'], ['A11.284.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Identical gene regulation patterns of T3 and selective thyroid hormone receptor modulator GC-1. | Synthetic selective thyroid hormone (TH) receptor (TR) modulators (STRM) exhibit beneficial effects on dyslipidemias in animals and humans and reduce obesity, fatty liver, and insulin resistance in preclinical animal models. STRM differ from native TH in preferential binding to the TRâ subtype vs. TRá, increased uptake... | ['Acetates', 'Angiopoietin-like 4 Protein', 'Angiopoietins', 'Animals', 'Binding Sites', 'Gene Expression Regulation', 'Hep G2 Cells', 'Humans', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Phenols', 'RNA, Small Interfering', 'Receptors, Thyroid Hormone', 'Thyroid Hormone Receptors alpha', 'Thyroid Hormone Receptors... | 22,067,320 | [['D02.241.081.018', 'D10.251.400.045'], ['D12.644.276.100.050.500', 'D12.776.467.100.050.500', 'D23.529.100.050.500'], ['D12.644.276.100.100', 'D12.776.467.100.100', 'D23.529.100.100'], ['B01.050'], ['G02.111.570.120'], ['G05.308'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ethical Reflections on Parenthood of Mentally Ill Patients]. | Ethical aspects towards the parenthood of mentally ill patients will be discussed in the German health care system. The "concept of an ethical therapist" offers new perspectives for solutions concerning the individual level. Structural and systemic problems require institutional and political configurations. The "ethic... | ['Germany', 'Humans', 'Mental Disorders', 'Mentally Ill Persons', 'Morals', 'Parenting'] | 29,969,819 | [['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.150.725'], ['F01.829.500', 'K01.752.566'], ['F01.829.263.370.310']] | ['Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Comparative testing of various pancreatic cancer stem cells results in a novel class of pancreatic-cancer-initiating cells. | No systemic therapy is effective against pancreatic cancer (PC). Pancreatic cancer stem cells (PCSC) are hypothesized to account for therapeutic resistance. Several PCSC subpopulations were reported, each characterized by different markers. To be able to target PCSC, we sought to better define this putative heterogenei... | ['Animals', 'Antigens, CD', 'Cell Line', 'Humans', 'Male', 'Mice', 'Middle Aged', 'Neoplastic Stem Cells', 'Pancreatic Neoplasms', 'Tumor Cells, Cultured'] | 22,963,768 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['M01.060.116.630'], ['A11.872.650'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['A11.251.860']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessment of sensory function in the operating room utilizing cerebral evoked potentials: a study of fifty-six surgically anesthetized patients. | Sensory evoked potentials (visual, auditory, and somatosensory) were recorded from 56 patients at the time of surgery to monitor neural function during critical portions of the operation. Fluctuations in latency and amplitude of the components occurred with changes in depth of anesthesia, blood pressure, irrigation, an... | ['Adolescent', 'Adult', 'Brain Stem', 'Child, Preschool', 'Evoked Potentials, Auditory', 'Evoked Potentials, Somatosensory', 'Evoked Potentials, Visual', 'Female', 'Humans', 'Intraoperative Period', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Sensation'] | 7,318,295 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211.132'], ['M01.060.406.448'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme A and its thioesters. | Stable isotope dilution mass spectrometry (MS) represents the gold standard for quantification of endogenously formed cellular metabolites. Although coenzyme A (CoA) and acyl-CoA thioester derivatives are central players in numerous metabolic pathways, the lack of a commercially available isotopically labeled CoA limit... | ['Animals', 'Cells, Cultured', 'Chromatography, Liquid', 'Coenzyme A', 'Esters', 'Hepatocytes', 'Isotope Labeling', 'Mice', 'Pantothenic Acid', 'Reproducibility of Results', 'Spectrometry, Mass, Electrospray Ionization'] | 21,268,609 | [['B01.050'], ['A11.251'], ['E05.196.181.400'], ['D03.633.100.759.646.138.382', 'D08.211.211', 'D13.695.667.138.382', 'D13.695.827.068.382'], ['D02.241.400'], ['A11.436.348'], ['E05.522'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.478.520', 'D12.125.042.070.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.36... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mitochondria-coupled glucose phosphorylation develops after birth to modulate H2 | The adult brain is a high-glucose and oxygen-dependent organ, with an extremely organized network of cells and large energy-consuming synapses. To reach this level of organization, early stages in development must include an efficient control of cellular events and regulation of intracellular signaling molecules and io... | ['Animals', 'Brain', 'Calcium', 'Glucose', 'Hexokinase', 'Hydrogen Peroxide', 'Mitochondria', 'Neurogenesis', 'Oxidative Phosphorylation', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species'] | 31,001,830 | [['B01.050'], ['A08.186.211'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D09.947.875.359.448'], ['D08.811.913.696.620.300'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G04.152.912', 'G07.345.500.3... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-endothelial KDR/flk-1 expression is associated with increased survival of patients with urothelial bladder carcinomas. | AIMS: To investigate the immunohistochemical expression of KDR/flk-1 in a series of 114 urothelial bladder carcinomas in relation to clinicopathological parameters, Ki67, p53 and Bcl-2 protein expression and patient survival. KDR/flk-1 is a high-affinity tyrosine kinase receptor for vascular endothelial growth factor (... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma', 'Female', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Proto-Oncogene Proteins c-bcl-2', 'Tumor Suppressor Protein p53', 'Urinary Bladder Neoplasms', 'Urothelium', 'Vascular Endothelial Growth Fact... | 12,940,780 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[CT urography in women with primary or recurrent pelvic tumors : background and initial experiences]. | Malignant tumors of the female pelvis account for 12-13% of newly diagnosed solid neoplasms among women in the USA and Germany. German guidelines advocate diagnostic imaging for local recurrence and metastasis while there are no recommendations for primary tumors. As excretory urography has been replaced by the excreto... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pelvic Neoplasms', 'Radiographic Image Enhancement', 'Tomography, X-Ray Computed', 'Urography', 'Young Adult'] | 21,698,344 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['C04.588.699'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Optimization of matrix formulation of effective parts cataplasm of Pogostemon cablin by uniform design]. | OBJECTIVE: To optimize the matrix formulation of the effective part Cataplasm of Pogostemon Cablin.METHOD: The optimal preparation prescription was selected by U17 (17(11)) uniform design,and the tacking strength, cohesive strength and transdermal speed constant were used as test indexes. The equations of three test in... | ['Adhesiveness', 'Biocompatible Materials', 'Chemistry, Pharmaceutical', 'Drugs, Chinese Herbal', 'Lamiaceae', 'Regression Analysis', 'Skin Absorption', 'Volatilization'] | 18,590,189 | [['G02.860.139'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['H01.158.703.007', 'H01.181.466'], ['D20.215.784.500.350', 'D26.335'], ['B01.650.940.800.575.912.250.583.520'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['G03.015.500.750', 'G03.787.024.500.750', 'G07.690.725.015.500.750', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
AtGEN1 and AtSEND1, two paralogs in Arabidopsis, possess holliday junction resolvase activity. | Holliday junctions (HJs) are physical links between homologous DNA molecules that arise as central intermediary structures during homologous recombination and repair in meiotic and somatic cells. It is necessary for these structures to be resolved to ensure correct chromosome segregation and other functions. In eukaryo... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Conserved Sequence', 'DNA, Cruciform', 'Holliday Junction Resolvases', 'Molecular Sequence Data', 'Sequence Homology, Amino Acid'] | 25,037,209 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.580'], ['D13.444.308.295', 'G02.111.570.820.486.325', 'G05.360.580.325'], ['D08.811.277.352.335.350.400', 'D08.811.277.352.355.325.400', 'D08.811.739.250'], ['L01.453.245.667'], ['G02.111.810.200', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Detection of vegetable oil adulteration in ice cream. | This study was to demonstrate the application of various analytical methods to the detection, identification, and quantitation of vegetable oil adulteration of ice cream. Total fat content, sterols, long- and short-chain fatty acids, vitamin E, Reichert-Meissl values, and Polenske values were measured in ice cream. All... | ['Chromatography, Gas', 'Colorimetry', 'Fatty Acids', 'Food Contamination', 'Ice Cream', 'Plant Oils', 'Sterols', 'Vitamin E'] | 3,842,847 | [['E05.196.181.349'], ['E05.196.922.250'], ['D10.251'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['G07.203.300.350.400', 'J02.500.350.400'], ['D10.627.700', 'D20.215.784.750'], ['D04.210.500.247.808', 'D10.570.938'], ['D03.383.663.283.909', 'D03.633.100.150.909']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Pannocytes: distinctive cells found in rheumatoid arthritis articular cartilage erosions. | A distinctive cell was identified from sites of rheumatoid arthritis cartilage injury. Similar cells are not found in lesions of osteoarthritis cartilage. We have designated them as pannocytes (PCs). Their rhomboid morphology differs from the bipolar shape of fibroblast-like synoviocytes or the spherical configuration ... | ['Antigens, Surface', 'Arthritis, Rheumatoid', 'Cartilage, Articular', 'Cell Division', 'Cell Membrane', 'Cells, Cultured', 'Collagenases', 'Cytoplasm', 'Fibroblasts', 'Genotype', 'Humans', 'Microscopy, Electron', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Receptors, Cytokine', 'Synovial Membrane'] | 9,060,847 | [['D23.050.301'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.149'], ['A11.251'], ['D08.811.277.656.300.480.205', 'D08.811.277.656.675.374.205'], ['A11.284.430.214'], ['A... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations Between Immune Phenotype and Inflammation in Murine Models of Irritant Contact Dermatitis. | Irritant contact dermatitis (ICD), the most common occupational cutaneous illness, is an acute inflammatory response caused by topical irritant exposure. Multiple factors are associated with the manifestation and severity of ICD and contribute to the lack of effective prophylactic and treatment strategies. To determine... | ['Animals', 'Benzalkonium Compounds', 'CD11 Antigens', 'Chemokines', 'Cytokines', 'Dermatitis, Irritant', 'Disease Models, Animal', 'Hydrocarbons', 'Inflammation', 'Irritants', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Monocytes', 'Neutrophils', 'Phenotype', 'Skin'] | 30,517,752 | [['B01.050'], ['D02.092.877.096.040', 'D02.675.276.080'], ['D12.776.395.550.200.074', 'D12.776.543.550.200.093', 'D23.050.301.350.074'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C17.800.174.255.400', 'C17.80... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemistry of LAMP-2 and adipophilin for phospholipidosis in liver and kidney in ketoconazole-treated mice. | Drug-induced phospholipidosis is an abnormal accumulation of phospholipids in the lysosomes following repeated administration of cationic amphiphilic drugs. Phospholipidosis is detected histopathologically as cytoplasmic vacuolation; however, it is difficult to distinguish from lipid accumulation since their morphologi... | ['Administration, Oral', 'Animals', 'Antifungal Agents', 'Immunohistochemistry', 'Ketoconazole', 'Kidney', 'Liver', 'Liver Function Tests', 'Lysosomal-Associated Membrane Protein 2', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Inbred ICR', 'Microscopy, Electron, Transmission', 'Organ Size', 'Perilipin-2', 'Phospholipid... | 23,276,623 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.122.136'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['D03.383.606.560'], ['A... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Diazepam loading: simplified treatment of alcohol withdrawal. | Alcohol withdrawal therapy can be simplified with a loading dose of diazepam, taking advantage of the kinetic tapering afforded by the drug's long t 1/2s and its metabolites, and of the effectiveness of nonpharmacologic maneuvers. In a double-blind trial, 50 inpatients in moderate to severe alcohol withdrawal received ... | ['Adult', 'Diazepam', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Ethanol', 'Female', 'Half-Life', 'Humans', 'Male', 'Middle Aged', 'Random Allocation', 'Substance Withdrawal Syndrome'] | 6,641,099 | [['M01.060.116'], ['D03.633.100.079.080.070.216'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.033.375'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.700', 'E05.581.500.805', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Light-induced pitch transitions in photosensitive cholesteric liquid crystals: effects of anchoring energy. | We experimentally study how the cholesteric pitch P depends on the equilibrium pitch P0 in planar liquid crystal (LC) cells with both strong and semistrong anchoring conditions. The cholesteric phase was induced by dissolution in the nematic LC of the right-handed chiral dopant 7-dehydrocholesterol (7-DHC, provitamin D... | ['Computer Simulation', 'Energy Transfer', 'Light', 'Liquid Crystals', 'Materials Testing', 'Models, Chemical', 'Models, Molecular', 'Radiation Dosage', 'Refractometry'] | 24,580,242 | [['L01.224.160'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['J01.637.506'], ['E05.570'], ['E05.599.495'], ['E05.599.595'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.196.808', 'H01.671.617.755']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Treatment of fatliquoring effluent from a tannery using membrane separation process: experimental and modeling. | Treatment of fatliquoring effluent generated from a tannery, using a hybrid separation process involving gravity settling, two step coagulation, nanofiltration and reverse osmosis is presented in this study. The optimum dose of coagulation, i.e., 0.5% (w/v) of ferrous sulfate followed by 0.15% (w/v) calcium oxide resul... | ['Diffusion', 'Fats', 'Filtration', 'Industrial Waste', 'Membranes, Artificial', 'Nanotechnology', 'Osmosis', 'Tanning', 'Waste Disposal, Fluid'] | 19,962,238 | [['G01.202', 'G02.196'], ['D10.212'], ['E05.196.454', 'G01.280', 'G02.263'], ['D20.944.420', 'N06.850.460.710.420'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['H01.603', 'J01.897.520.600'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495'], ['J01.576.852'], ['N06.850.780.200.800.800.890', 'N06.850.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Results of urinary undiversion in children. | Urinary undiversion was performed in 31 patients. Preoperative investigation and criteria for undiversion are discussed. Renal preservation rate is stable in 28 of 31 patients and bladder function satisfactory in 30 of 31 patients. Although prolongation of life and prevention of renal deterioration are of primary conce... | ['Adolescent', 'Child', 'Child, Preschool', 'Constriction, Pathologic', 'Female', 'Humans', 'Infant', 'Male', 'Reoperation', 'Ureter', 'Urinary Bladder', 'Urinary Bladder Diseases', 'Urinary Bladder, Neurogenic', 'Urinary Diversion', 'Urinary Tract', 'Urodynamics'] | 6,823,719 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C23.300.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04.690'], ['A05.810.776'], ['A05.810.890'], ['C12.777.829', 'C13.351.968.829'], ['C10.597.900', 'C12.777.829.839', 'C13.351.968.829.760', 'C23.888.592.900'], ['E04.950.774.852'],... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Directly observed antiretroviral therapy improves adherence and viral load in drug users attending methadone maintenance clinics: a randomized controlled trial. | OBJECTIVE: To determine if directly observed antiretroviral therapy (DOT) is more efficacious than self-administered therapy for improving adherence and reducing HIV viral load (VL) among methadone-maintained opioid users.DESIGN: Two-group randomized trial.SETTING: Twelve methadone maintenance clinics with on-site HIV ... | ['Antiretroviral Therapy, Highly Active', 'Directly Observed Therapy', 'Female', 'HIV Infections', 'Humans', 'Male', 'Medication Adherence', 'Methadone', 'Middle Aged', 'Opiate Substitution Treatment', 'Opioid-Related Disorders', 'Substance Abuse Treatment Centers', 'Viral Load'] | 20,832,196 | [['E02.319.310.075'], ['F01.100.150.750.500.600.500.500', 'F01.145.488.887.500.600.500.500', 'N05.300.150.800.500.600.500.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does TAL-1 deletion contribute to the high incidence of T-cell acute lymphoblastic leukemia in South Indian patients? | BACKGROUND: The incidence of T-cell acute lymphoblastic leukemia (T-ALL) in South India is very high (43.1%) when compared to the Western countries (10-20%). TAL-1 deletion is the most common genetic abnormality in T-ALL.OBJECTIVES: The present study was aimed to detect the incidence of type 1 and type 2 TAL-1 deletion... | ['Adolescent', 'Adult', 'Basic Helix-Loop-Helix Transcription Factors', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Incidence', 'India', 'Male', 'Polymerase Chain Reaction', 'Precursor T-Cell Lymphoblastic Leukemia-Lymphoma', 'Proto-Oncogene Proteins', 'Sequence Deletion', 'T-Cell Acute Lymphocytic Leukemia Prote... | 18,439,091 | [['M01.060.057'], ['M01.060.116'], ['D12.776.260.103', 'D12.776.930.125'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.252.245.393'], ['E05.393.620.500'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients. | The outcome of resectable non-small cell lung cancer (NSCLC) is critically determined by metastatic spread: About 30-50% of early-stage NSCLC patients encounter tumour recurrence within 5 years after surgery. A biomarker-driven stratification of early-stage lung cancer with a high risk of recurrence may improve therapy... | ['Adenocarcinoma', 'Adenocarcinoma of Lung', 'Aged', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Gene Expression Regulation, Neoplastic', 'Genetic Association Studies', 'Humans', 'Lung Neoplasms', 'Male', 'MicroRNAs', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Prognosis', 'R... | 23,410,826 | [['C04.557.470.200.025'], ['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['M01.060.116.100'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G05.308.370'], ['E05.393.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.3... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cellular stress and apoptosis contribute to the pathogenesis of autism spectrum disorder. | The molecular pathogenesis of autism spectrum disorder, a neurodevelopmental disorder, is still elusive. In this study, we investigated the possible roles of endoplasmic reticulum (ER) stress, oxidative stress, and apoptosis as molecular mechanisms underlying autism. This study compared the activation of ER stress sign... | ['Adolescent', 'Apoptosis', 'Autism Spectrum Disorder', 'Brain', 'Child', 'Child, Preschool', 'Endoplasmic Reticulum Stress', 'Endoribonucleases', 'Humans', 'Male', 'Oxidative Stress', 'Protein-Serine-Threonine Kinases', 'eIF-2 Kinase'] | 29,761,862 | [['M01.060.057'], ['G04.146.954.035'], ['F03.625.164.113'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['G04.434'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.673', 'G07.775.750'], ['D08.811.913.696.620.682.700'], ['D08.811.913.696.620.682.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Moving on: Factors associated with caregivers' bereavement adjustment using a random population-based face-to-face survey. | BACKGROUND: Providing care at end of life has consequences for caregivers' bereavement experience. 'Difficulty moving on with life' is an informative and unbiased symptom of prolonged grief disorder. Predictors of bereaved caregivers' ability to 'move on' have not been examined across the population.AIM: To identify th... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Death', 'Bereavement', 'Caregivers', 'Cross-Sectional Studies', 'Female', 'Grief', 'Humans', 'Male', 'Middle Aged', 'South Australia', 'Surveys and Questionnaires', 'Young Adult'] | 28,627,971 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.125', 'N05.300.125'], ['F01.470.142'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.470.142.110'], ['B01.050.150.900.649.313.988.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Photography in vivo of epithelial lesions in the human cornea with non-contact high magnification technique. | A technique is described for high magnification in vivo photography of epithelial lesions in the human cornea. Combining use of a high resolution, long working-distance microscope type lens with two-step photographic enlargement techniques results in photomacrographs with effective linear magnification of up to 500 X. ... | ['Adolescent', 'Adult', 'Cornea', 'Corneal Injuries', 'Epithelium', 'Female', 'Humans', 'Male', 'Microscopy', 'Middle Aged', 'Photography'] | 3,425,260 | [['M01.060.057'], ['M01.060.116'], ['A09.371.060.217'], ['C10.900.300.284.250.124', 'C11.204.284', 'C11.297.374', 'C26.915.300.425.250.124'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['M01.060.116.630'], ['E01.370.350.600', 'E05.712']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Opening vesical pressure: a new test to discriminate urethral sphincter deficiency? | Urethral sphincter deficiency (USD) is not standardised. Opening vesical pressure could reflect the pressure exerted to overcome urethral resistance during void; thus, we evaluated if it could discriminate USD. Women with urinary symptoms were prospectively assessed with a questionnaire and urodynamics and divided into... | ['Anal Canal', 'Diagnosis, Differential', 'Female', 'Humans', 'Pressure', 'Surveys and Questionnaires', 'Urethral Diseases'] | 17,479,203 | [['A03.556.124.526.070', 'A03.556.249.249.070'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.715'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['C12.777.767', 'C13.351.968.767']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A rapid radioimmunoassay, using a nylon support, for amatoxins from Amanita mushrooms. | A fetuin derivative of alpha-amanitin was prepared and used as an antigen in rabbits. The antigen was superior to previous bovine serum albumin derivatives of beta-amanitin by its lower toxicity and high immunogenicity. On the other hand, the antibodies raised with the alpha-amanitin derivative did not show full crossr... | ['Agaricales', 'Amanita', 'Amanitins', 'Animals', 'Antigens', 'Cross Reactions', 'Immunization', 'Immunoglobulins', 'Nylons', 'Rabbits', 'Radioimmunoassay'] | 6,891,119 | [['B01.300.179.100'], ['B01.300.179.100.110'], ['D04.345.566.050', 'D12.644.456.050', 'D12.644.641.050', 'D23.946.587.175'], ['B01.050'], ['D23.050'], ['G12.122.281'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['D12.776.124.486.485', 'D12.776.124.790.65... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Double mutation of BRF1 and BRF2 leads to sterility in Arabidopsis thaliana. | The TFIIB-related factor (BRF) family plays vital roles in RNA polymerase (Pol) III transcription initiation. However, little is known about the role of BRF in plants. Here, we report BRF1 and BRF2 are involved in Arabidopsis reproduction. In this study, we generated BRF1 and BRF2 double mutant plants. We found that no... | ['Arabidopsis', 'Arabidopsis Proteins', 'Crosses, Genetic', 'Gene Expression Regulation, Plant', 'Mutation', 'Plant Infertility', 'Pollen', 'Protein Isoforms', 'RNA Polymerase III', 'Reproduction', 'Transcription Factor TFIIB', 'Transcription Factors', 'Transcription, Genetic', 'Zygote'] | 31,277,948 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['E05.393.281'], ['G05.308.375'], ['G05.365.590'], ['G15.649'], ['A18.024.249.500.249.500'], ['D12.776.800'], ['D08.811.913.696.445.735.270.775'], ['G08.686.784'], ['D12.776.260.775.875.562', 'D12.776.930.930.875.562'], ['D12.776.930'], ['G02.111.873', 'G05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimization of intercalation dye concentration for short tandem repeat allele genotyping using capillary electrophoresis with laser-induced fluorescence detection. | DNA analysis using capillary electrophoresis (CE) with laser-induced fluorescence (LIF) detection requires that polymerase chain reaction products either be prepared using primers with fluorescent molecules covalently bonded to them, or stained with a fluorescent intercalation dye following amplification. The intercala... | ['Alleles', 'Benzoxazoles', 'DNA', 'Electrophoresis, Capillary', 'Genotype', 'Intercalating Agents', 'Lasers', 'Quinolinium Compounds', 'Reference Standards', 'Spectrometry, Fluorescence', 'Tandem Repeat Sequences'] | 10,517,359 | [['G05.360.340.024.340.030'], ['D03.633.100.221'], ['D13.444.308'], ['E05.196.401.190', 'E05.301.300.190'], ['G05.380'], ['D27.720.470.410.360'], ['E07.632.490', 'E07.710.520'], ['D03.633.100.810.824'], ['E05.978.808'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Periodic lateralised epileptiform discharges as a form of presentation of neurosyphilis]. | INTRODUCTION: Neurosyphilis is a recognised cause of epileptic seizures, but its association with periodic lateralised epileptiform discharges (PLED) has been described only rarely, in spite of the fact that it gives rise to acute vascular lesions.CLINICAL CASE: We report the case of a male patient who was diagnosed as... | ['Alcoholism', 'Anticonvulsants', 'Brain Ischemia', 'Cerebral Infarction', 'Electroencephalography', 'Epilepsy, Tonic-Clonic', 'Humans', 'Language Disorders', 'Male', 'Middle Aged', 'Neurosyphilis', 'Penicillins', 'Phenytoin', 'Smoking', 'Syphilis Serodiagnosis'] | 12,402,225 | [['C25.775.100.250', 'F03.900.100.350'], ['D27.505.954.427.080'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['E01.370.376.300', 'E01.370.405.245']... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Consultations with complementary and alternative medicine practitioners by older Australians: results from a national survey. | BACKGROUND: The use of complementary and alternative medicines (CAM) and CAM practitioners is common, most frequently for the management of musculoskeletal conditions. Knowledge is limited about the use of CAM practitioners by older people, and specifically those with other long term or chronic conditions.METHODS: In 2... | ['Aged', 'Aged, 80 and over', 'Australia', 'Chronic Disease', 'Complementary Therapies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Musculoskeletal Diseases', 'Patient Acceptance of Health Care', 'Patients', 'Physicians', 'Referral and Consultation', 'Surveys and Questionnaires'] | 23,548,137 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['C23.550.291.500'], ['E02.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['M01.643'], ['M01.526.485.810', 'N02.360.810'], ['N0... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Formaldehyde oxidation and methanogenesis. | Formaldehyde oxidation by cell-free extracts of Methanobacterium thermoautotrophicum was shown to drive methanogenesis from CH3-S-coenzyme M or HCHO under a nonreductive atmosphere of N2. Under N2 when HCHO was the sole source of carbon and reducing equivalents in the reaction, it underwent oxidation and reduction even... | ['Euryarchaeota', 'Formaldehyde', 'Mesna', 'Methane', 'NADP', 'Oxidation-Reduction', 'Pterins'] | 6,427,185 | [['B02.200'], ['D02.047.407'], ['D02.455.326.146.100.050.490', 'D02.886.489.590', 'D02.886.645.600.055.050.500'], ['D02.455.326.146.571'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['G02.700', 'G03.295.531'], ['D03.633.100.733.631', 'D23.767.831']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Control of erosive tooth wear: possibilities and rationale. | Dental erosion is a type of wear caused by non bacterial acids or chelation. There is evidence of a significant increase in the prevalence of dental wear in the deciduous and permanent teeth as a consequence of the frequent intake of acidic foods and drinks, or due to gastric acid which may reach the oral cavity follow... | ['Acids', 'Dentifrices', 'Feeding Behavior', 'Fluorides, Topical', 'Food', 'Humans', 'Oral Health', 'Risk Factors', 'Saliva', 'Self Care', 'Sodium Bicarbonate', 'Tooth Erosion', 'Tooth Remineralization'] | 19,838,558 | [['D01.029'], ['D25.376', 'D27.720.269.380', 'J01.637.051.376'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D01.303.350.300.512', 'D25.223.432', 'J01.637.051.223.432'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.400.535'], ['E05.318.740.600.800.725', 'N05.715.350.20... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Structural characterization of novel L-galactose-containing oligosaccharide subunits of jojoba seed xyloglucans. | Jojoba seed xyloglucan was shown to be a convenient source of biologically active xyloglucan oligosaccharides that contain both L- and D-galactosyl residues [E. Zablackis et al., Science, 272 (1996) 1808-1810]. Oligosaccharides were isolated by liquid chromatography of the mixture of oligosaccharides generated by treat... | ['Borohydrides', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Cellulase', 'Chromatography, Gel', 'Fucose', 'Galactose', 'Glucans', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Molecular Sequence Data', 'Oligosaccharides', 'Polysaccharides', 'Seeds', 'Sugar Alcohols', 'Xylans', 'Xylose'] | 9,403,992 | [['D01.132.105.050', 'D02.203.087.050'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D08.811.277.450.420.200.200'], ['E05.196.181.400.250'], ['D09.254.488'], ['D09.947.875.359.377'], ['D05.750.078.562', 'D09.698.365'], ['E05.196.867.519'], ['E05.196.566'], ['L01.453.245.667'], ['D09.698.629']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Feeding habits and severe early childhood caries in Brazilian preschool children. | PURPOSE: The objective of this study was to analyze the association between the feeding practice and presence or absence of SECC (Severe Early Childhood Caries) in Brazilian preschool children.METHODS: This cross-sectional study was conducted with male and female preschool children, aged 36 to 71 months, randomly selec... | ['Age Distribution', 'Bottle Feeding', 'Brazil', 'Breast Feeding', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Dental Caries', 'Diet, Cariogenic', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'Poverty', 'Prevalence'] | 15,839,392 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E02.421.150', 'F01.145.407.099', 'G07.203.650.220.500.250', 'G07.203.650.353.099'], ['Z01.107.757.176'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', '... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Rare variant detection using family-based sequencing analysis. | Next-generation sequencing is revolutionizing genomic analysis, but this analysis can be compromised by high rates of missing true variants. To develop a robust statistical method capable of identifying variants that would otherwise not be called, we conducted sequence data simulations and both whole-genome and targete... | ['Bayes Theorem', 'Family', 'Female', 'Genetic Variation', 'Genome, Human', 'Humans', 'Kidney Neoplasms', 'Likelihood Functions', 'Male', 'Mitochondrial Diseases', 'Models, Genetic', 'Neurodegenerative Diseases', 'Pedigree', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA', 'Software', 'Wilms Tumor'] | 23,426,633 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['F01.829.263', 'I01.880.853.150'], ['G05.365'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E05.318.74... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension: indications for a seminal role for mitochondrial Nox4. | Pulmonary arterial hypertension is a severe progressive disease with marked morbidity and high mortality in which right ventricular (RV) failure is the major cause of death. Thus knowledge of the mechanisms underlying RV failure is an area of active interest. Previous studies suggest a role of NADPH oxidase in cardiomy... | ['Animals', 'Catalase', 'Glutathione Peroxidase', 'Heart Ventricles', 'Hypertension, Pulmonary', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred C57BL', 'Mitochondria', 'NADPH Oxidase 2', 'NADPH Oxidase 4', 'NADPH Oxidases', 'RNA, Messenger', 'Reactive Oxygen Species', 'Superoxide Dismutase', 'Up-Regulation', '... | 24,213,612 | [['B01.050'], ['D08.811.682.732.332'], ['D08.811.682.732.500'], ['A07.541.560'], ['C08.381.423', 'C14.907.489.556'], ['D12.776.395.550', 'D12.776.543.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.284.430.214.190.875.564', 'A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma protein binding of drugs after severe burn injury. | Plasma protein binding in seven severely burned (35% to 85% of body) patients 1 to 25 days after burn injury was examined for two drugs: diazepam (DZ), which binds mainly to serum albumin (ALB), and imipramine (IMI), which binds primarily to alpha 1-acid glycoprotein (AAG). Protein binding was determined by equilibrium... | ['Adolescent', 'Adult', 'Burns', 'Child, Preschool', 'Diazepam', 'Female', 'Humans', 'Imipramine', 'Male', 'Orosomucoid', 'Protein Binding', 'Serum Albumin'] | 6,705,453 | [['M01.060.057'], ['M01.060.116'], ['C26.200'], ['M01.060.406.448'], ['D03.633.100.079.080.070.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.300.240.485'], ['D12.776.124.050.600', 'D12.776.124.790.106.640', 'D12.776.377.715.085.640', 'D12.776.395.560.742'], ['G02.111.679', 'G03.808'], ['D12.776.034.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthetic mycobacterial molecular patterns partially complete Freund's adjuvant. | Complete Freund's adjuvant (CFA) has historically been one of the most useful tools of immunologists. Essentially comprised of dead mycobacteria and mineral oil, we asked ourselves what is special about the mycobacterial part of this adjuvant, and could it be recapitulated synthetically? Here, we demonstrate the essent... | ['Acetylmuramyl-Alanyl-Isoglutamine', 'Animals', 'Dendritic Cells', 'Female', "Freund's Adjuvant", 'Immunity, Cellular', 'Lectins, C-Type', 'Lymph Nodes', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mycobacterium', 'Nod2 Signaling Adaptor Protein', 'Peptidoglycan'] | 32,246,076 | [['D09.067.550.050', 'D09.811.522.050', 'D12.644.233.050'], ['B01.050'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D20.475'], ['G12.450.050.400'], ['D12.776.503.280'], ['A10.549.400', 'A15.382.520.604.412'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.52... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Generation of a parainfluenza virus type 1 vaccine candidate by replacing the HN and F glycoproteins of the live-attenuated PIV3 cp45 vaccine virus with their PIV1 counterparts. | Parainfluenza virus type 1 (PIV1) is a major cause of croup in infants and young children, and a vaccine is needed to prevent the serious disease caused by this virus. In the present study, a live attenuated PIV1 vaccine candidate was generated by modification of the extensively-studied PIV3 cold-passaged (cp) cp45 vac... | ['Animals', 'Cricetinae', 'HN Protein', 'Mesocricetus', 'Parainfluenza Virus 1, Human', 'Respiratory System', 'Vaccines, Attenuated', 'Vaccines, Synthetic', 'Viral Fusion Proteins', 'Viral Vaccines', 'Virus Replication'] | 10,519,940 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['D12.776.964.970.880.350', 'D23.050.327.461.350'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['B04.820.480.937.600.650.700.715'], ['A04'], ['D20.215.894.811'], ['D12.776.828.868', 'D20.215.894.865', 'D23.050.865'], ['D12.776.543.512.500', 'D12.776.964.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Expression in Escherichia coli of the gspd(l) gene of the type II secretion system in Leptospira borgpetersenii serovariety hardjo]. | A fragment of 1.539 pb of the gene homologous to gspD of Hardjobovis was clonated in the pET28a vector and it was transformed into E. coli C43 and Rosetta strains. The sequence of GspD(L) showed 46 % of similitude with E. coli GspD secretin. The expression of recombinant GspD(L) was obtained in Rosetta strain. | ['Animals', 'Cattle', 'Cattle Diseases', 'Escherichia coli', 'Escherichia coli Proteins', 'Gene Expression', 'Genes, Bacterial', 'Humans', 'Leptospira', 'Leptospirosis', 'Transformation, Bacterial'] | 17,966,476 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.297'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.400.425.475.475'... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oxidation of benzo[a]pyrene by the filamentous fungus Cunninghamella elegans. | Cunninghamella elegans oxidized benzo[a]pyrene to several metabolic products. Compounds that were isolated and identified were: trans-9,10-dihydroxy-9,10-dihydrobenzo[a]pyrene, trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, benzo[a]pyrene 1,6-quinone, benzo[a]pyrene 3,6-quinone, 9-hydroxybenz[a]pyrene, and 3-hydroxyben... | ['Benzopyrenes', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Kinetics', 'Mucorales', 'Oxidation-Reduction', 'Spectrophotometry'] | 500,703 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A prospective study of injury patterns in high school pole vaulters. | BACKGROUND: The pole vault is a track and field event that has witnessed a large increase in participants during the past 5 years. Currently there are no prospective studies that have evaluated injury patterns in pole vaulters.OBJECTIVES: To determine the injury rate and to describe injury patterns in high school pole ... | ['Adolescent', 'Athletic Injuries', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Risk Factors', 'Track and Field', 'Wisconsin'] | 18,326,831 | [['M01.060.057'], ['C26.115'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['I03.450.642.845.925'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Extragenic suppression of a ts phenotype during recombination between ts mutants of two fowl plague virus strains with a ts mutation in gene 1. | Fowl plague virus (FPV) ts mutants belonging to six recombination groups and obtained from the Weybridge strain (in the U.S.S.R.) or the Rostock strain (in the U.K.) have been studied in a recombination test. Temperature-sensitive mutants obtained from different FPV strains were revealed which had a ts mutation in gene... | ['Gene Expression Regulation', 'Genes, Viral', 'Influenza A virus', 'Mutation', 'Recombination, Genetic', 'Suppression, Genetic', 'Temperature'] | 7,142,971 | [['G05.308'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['B04.820.480.968.405.400'], ['G05.365.590'], ['G05.728'], ['G05.365.590.835', 'G05.558.835'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Subpopulation of dorsal horn neurons displays enhanced N-methyl-D-aspartate receptor function after chronic morphine exposure. | BACKGROUND: Morphine tolerance may be attributed to enhancement of glutamatergic neurotransmission, in particular to increased function of the N-methyl-D-aspartate (NMDA) receptor. The cellular mechanisms responsible for these changes remain poorly defined. The authors identified and characterized a specific subpopulat... | ['2-Amino-5-phosphonovalerate', 'Animals', 'Magnesium', 'Morphine', 'N-Methylaspartate', 'Naloxone', 'Posterior Horn Cells', 'Rats', 'Rats, Wistar', 'Receptors, N-Methyl-D-Aspartate'] | 16,571,979 | [['D12.125.070.950.100', 'D12.125.740.025'], ['B01.050'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reproductive health in diabetic women. A report of two cases demonstrating the importance of preconception care. | BACKGROUND: Optimal glycemic control prior to and during early pregnancy is essential in diabetic women.CASES: Two cases of fetal anencephaly occurred in diabetic women who conceived with medical technical assistance but did not receive preconception counseling. Both women had poor glycemic control periconceptually, as... | ['Adult', 'Anencephaly', 'Blood Glucose', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Patient Education as Topic', 'Pregnancy', 'Pregnancy in Diabetics', 'Prenatal Care'] | 9,749,421 | [['M01.060.116'], ['C10.500.680.196', 'C16.131.085.197', 'C16.131.666.680.196'], ['D09.947.875.359.448.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.233.332.500', 'N02.421.726.407.680'], ['G08.686.784.769'], ['C13.703.726'], ['E02.760.786', 'N02.421... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Antigen aerosols induce lung nonresponsiveness. | Guinea pigs intranasally dusted with ragweed pollen (RW) for one month went into anaphylaxis in ragweed extract aerosol (RWEA). Animals which received RWEA pretreatment for one month before nasal dusting with RW pollen were nonresponsive to RWEA. The purpose of this study was to define the mechanism of nonresponsivenes... | ['Administration, Intranasal', 'Administration, Oral', 'Aerosols', 'Anaphylaxis', 'Animals', 'Antibodies', 'Antigen-Antibody Reactions', 'Antigens', 'Binding, Competitive', 'Guinea Pigs', 'Histamine', 'Immunization', 'Lung', 'Pollen'] | 7,065,638 | [['E02.319.267.120.655.500'], ['E02.319.267.100'], ['D20.280.055', 'D26.255.165.055'], ['C20.543.480.099'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.122'], ['D23.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B01.050.150.900.649.313.992.550']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Rectal tonsil or lymphoid follicular hyperplasia of the rectum]. | The rectal tonsil is a reactive proliferation of lymphoid tissue located in the rectum. The morphology of the lymphoid proliferation of the colon is usually polypoid or, less commonly, nodular. Only in exceptional cases does lymphoid proliferation of the colon present as a mass in the rectum (rectal tonsil), although t... | ['Child, Preschool', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Pseudolymphoma', 'Rectal Diseases'] | 22,112,591 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C15.604.613'], ['C06.405.469.860']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The influence of gender on the classification of psychotic disorders--a multidiagnostic approach. | A multidiagnostic approach was used prospectively to classify a sample of 176 psychotic patients. An excess of males was found with only one out of 11 systems of schizophrenia, the World Health Organization "flexible" system of schizophrenia, with an excess of females noted in 2 of 5 systems of schizoaffective disorder... | ['Acute Disease', 'Adolescent', 'Adult', 'Affective Disorders, Psychotic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Psychotic Disorders', 'Schizophrenia', 'Sex Factors'] | 2,399,825 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['F03.700.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['F04.711.513.653'], ['F03.700.675'], ['F03.700.750'], ['N05.715.350.675', 'N06.850.49... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A decade of experience with the glutaraldehyde-tanned human umbilical cord vein graft for revascularization of the lower limb. | Between October 1975 and November 1985, 907 lower limb bypasses were constructed in 715 patients (799 limbs) with glutaraldehyde-stabilized umbilical veins (UV-G) used as the predominant, or sole, graft material. Each reconstruction was classified in one of eight categories depending on the site of the distal anastomos... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Aldehydes', 'Bioprosthesis', 'Blood Vessel Prosthesis', 'Evaluation Studies as Topic', 'Female', 'Follow-Up Studies', 'Glutaral', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Time Factors', 'Umbilical Veins'] | 3,123,718 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.047'], ['E07.695.100'], ['E07.695.110'], ['E05.337', 'N05.715.360.335'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D02.047.532'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tacrolimus (FK 506) overdose: a report of five cases. | INTRODUCTION: Tacrolimus (FK 506), a potent anti-T cell agent, has been shown to be effective in preventing the rejection of transplanted organs. Published research on tacrolimus has focused on effects associated with therapeutic use. Virtually no literature addresses the acute toxicity or the management of tacrolimus ... | ['Adult', 'Anti-Bacterial Agents', 'Charcoal', 'Child, Preschool', 'Drug Overdose', 'Female', 'Humans', 'Immunosuppressive Agents', 'Male', 'Tacrolimus'] | 9,204,100 | [['M01.060.116'], ['D27.505.954.122.085'], ['D01.268.150.150'], ['M01.060.406.448'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['D02.540.505.810']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Network identification of hormonal regulation. | Relations among hormone serum concentrations are complex and depend on various factors, including gender, age, body mass index, diurnal rhythms and secretion stochastics. Therefore, endocrine deviations from healthy homeostasis are not easily detected or understood. A generic method is presented for detecting regulator... | ['Cohort Studies', 'Computer Simulation', 'Female', 'Hormones', 'Humans', 'Models, Biological', 'Obesity', 'Perimenopause', 'Periodicity'] | 24,852,517 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.224.160'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['G08.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Action of tamoxifen on folliculogenesis in the menstrual cycle of infertile patients. | Daily estimations of follicle-stimulating hormone, luteinizing hormone, prolactin, estradiol, and progesterone were made in the serum of eight infertile patients from day 1 through the follicular phase during menstrual cycles before and after tamoxifen therapy. Tamoxifen therapy was found to shorten the follicular phas... | ['Adult', 'Estradiol', 'Female', 'Follicular Phase', 'Gonadotropins, Pituitary', 'Humans', 'Infertility, Female', 'Luteal Phase', 'Luteinizing Hormone', 'Menotropins', 'Progesterone', 'Prolactin', 'Stimulation, Chemical', 'Tamoxifen'] | 6,409,673 | [['M01.060.116'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.605.310'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D12.644.548.691.525.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['G08.686.605.410'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.34... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of radiotherapy in carcinoma of the thoracic oesophagus: an audit of the Mount Vernon experience 1980-1989. | All 244 patients with carcinoma of the thoracic oesophagus registered at the Mount Vernon Centre for Cancer Treatment during the decade from 1 January 1980 to 31 December 1989 have been audited. We have made a detailed analysis of 110 (45%) with localized disease considered unsuitable for surgery, who completed treatme... | ['Age Factors', 'Cancer Care Facilities', 'Carcinoma, Squamous Cell', 'Cause of Death', 'Deglutition Disorders', 'England', 'Esophageal Neoplasms', 'Humans', 'Life Tables', 'Medical Audit', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Palliative Care', 'Radiotherapy, High-Energy', 'Remission Induction', 'Sex F... | 1,372,818 | [['N05.715.350.075', 'N06.850.490.250'], ['N02.278.421.556.070'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C06.405.117.119', 'C09.775.174'], ['Z01.542.363.300'], ['C04.588.274.476.205', 'C04.588.44... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Ethno-ornithology and conservation of wild birds in the semi-arid Caatinga of northeastern Brazil. | The utilization of birds as pets has been recognized as one of the principal threats to global avifauna. Most of the information about the use and sale of birds as pets has been limited to areas of high biodiversity and whose impacts of anthropic actions have been widely broadcast internationally, for example for the A... | ['Animals', 'Biodiversity', 'Birds', 'Brazil', 'Conservation of Natural Resources', 'Humans', 'Pets'] | 23,445,769 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B01.050.150.900.248'], ['Z01.107.757.176'], ['J01.256', 'N06.230.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.116.600']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Comparison of end-expiratory respiratory gating methods for PET/CT. | BACKGROUND: Respiratory motion in positron emission tomography/computed tomography (PET/CT) causes underestimation of standardized uptake value (SUV) and variation of lesion volume, while PET and CT attenuation correction (CTAC) mismatch may introduce artefacts. The aim was to compare end-expiratory gating methods of P... | ['Artifacts', 'Exhalation', 'Four-Dimensional Computed Tomography', 'Humans', 'Movement', 'Multimodal Imaging', 'Positron-Emission Tomography'] | 24,960,580 | [['E05.047'], ['G09.772.705.700.275'], ['E01.370.350.350.810.490', 'E01.370.350.400.350', 'E01.370.350.700.700.810.490', 'E01.370.350.700.810.810.645', 'E01.370.350.825.810.810.599'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['E01.370.350.567'], ['E01.370.350.350.800.700', 'E01.370.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Organs at risk and target volumes: definition for conformal radiation therapy in breast cancer]. | Adjuvant radiotherapy is a standard component of breast cancer treatment. The addition of radiotherapy after breast conserving surgery has been shown to reduce local recurrence rate and improve long-term survival. Accurate delineation of target volumes and organs at risk is crucial to the quality of treatment planning ... | ['Breast Neoplasms', 'Female', 'Humans', 'Lymph Nodes', 'Organs at Risk', 'Radiotherapy, Adjuvant', 'Radiotherapy, Conformal'] | 22,925,488 | [['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['A01.635'], ['E02.186.775', 'E02.815.600'], ['E02.815.635.700', 'L01.313.500.750.100.710.600.550']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Control of catalase and peroxidase biosynthesis by carbon source and oxygen in the yeast Saccharomyces cerevisiae. | The effect of carbon source and oxygen tension on catalase and peroxidase levels and on the intermediates of the biosynthesis of the prosthetic group of both enzymes has been studied. Oxygen produces an increase of both enzymatic activities, even in presence of glucose. On the other hand it seems probable that glucose ... | ['Aerobiosis', 'Aminolevulinic Acid', 'Anaerobiosis', 'Catalase', 'Culture Media', 'Cytochrome-c Peroxidase', 'Enzyme Repression', 'Kinetics', 'Lactates', 'Lactic Acid', 'Peroxidases', 'Porphyrins', 'Saccharomyces cerevisiae'] | 6,317,151 | [['G02.111.017', 'G03.049'], ['D02.241.755.547.276', 'D12.125.262'], ['G02.111.062', 'G03.078'], ['D08.811.682.732.332'], ['D27.720.470.305', 'E07.206'], ['D08.811.682.732.380'], ['G05.308.320.300'], ['G01.374.661', 'G02.111.490'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['D08.811.682.732'], ['D03.383.129.578.840... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A model hospital policy on prosecuting patients for presumptively criminal acts. | Evidence suggests that violence by psychiatric inpatients, especially in public-sector hospitals, may be on the rise. The authors present a model policy developed at a state hospital for deciding whether to prosecute presumptively criminal assaults by patients. The policy addresses the circumstances under which it is e... | ['Confidentiality', 'Crime', 'Dangerous Behavior', 'Ethics, Institutional', 'Hospital-Patient Relations', 'Hospitals, Psychiatric', 'Hospitals, State', 'Humans', 'Mental Disorders', 'Organizational Policy', 'Patient Care Team', 'Personnel, Hospital', 'United States', 'Violence'] | 1,810,861 | [['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['I01.198.240', 'I01.880.735.191'], ['F01.145.263', 'I01.880.735.223'], ['K01.752.566.479.168', 'N05.350.325'], ['N02.278.216.500.992', 'N04.452.822.370'], ['N02.278.421.556.508'], ['N02.278.421.510.300... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The Edinburgh cohort of HIV-positive drug users: current intellectual function is impaired, but not due to early AIDS dementia complex. | Eighty people, all infected by HIV-contaminated drug injection equipment between 1983 and 1984, completed the National Adult Reading Test (NART) and selected revised Wechsler Adult Intelligence Scale (WAIS-R) subtests. Demographic variables (age, sex, years of education, and social class) were recorded as additional in... | ['AIDS Dementia Complex', 'Adult', 'Cohort Studies', 'Cross-Sectional Studies', 'Female', 'HIV Infections', 'HIV Seropositivity', 'Humans', 'Intelligence', 'Male', 'Neuropsychology', 'Scotland', 'Substance Abuse, Intravenous'] | 2,397,057 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Production of TNF-alpha by human V gamma 9V delta 2 T cells via engagement of Fc gamma RIIIA, the low affinity type 3 receptor for the Fc portion of IgG, expressed upon TCR activation by nonpeptidic antigen. | Human lymphocytes expressing the gammadelta TCR represent a minor T cell subpopulation found in blood. The majority of these cells express Vgamma9Vdelta2 determinants and respond to nonpeptidic phosphoantigens. Several studies have shown that, in vivo, the percentage of Vgamma9Vdelta2 T cells dramatically increases dur... | ['Antibodies, Monoclonal', 'Antigens, Bacterial', 'Antigens, CD', 'Cells, Cultured', 'Down-Regulation', 'Hemiterpenes', 'Humans', 'Immune Sera', 'Immunoglobulin Fc Fragments', 'Immunoglobulin G', 'Lectins, C-Type', 'Lymphocyte Activation', 'MAP Kinase Kinase 2', 'MAP Kinase Signaling System', 'Membrane Glycoproteins', ... | 11,390,467 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.161'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D02.455.849.486'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene expression data analysis in subtypes of ovarian cancer using covariance analysis. | Many studies have used microarray technology to identify the molecular signatures of human cancer, yet the critical features of these often unmanageably large set of signatures remain elusive. We have investigated co-expression pattern in four subtypes of ovarian cancer from 104 cancer patients using covariance analysi... | ['Biomarkers, Tumor', 'Diagnosis, Computer-Assisted', 'Female', 'Gene Expression Profiling', 'Humans', 'Multigene Family', 'Neoplasm Proteins', 'Oligonucleotide Array Sequence Analysis', 'Ovarian Neoplasms', 'Regression Analysis', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 17,099,938 | [['D23.101.140'], ['E01.158', 'L01.313.500.750.100.158'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.340.645'], ['D12.776.624'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Acoustical analysis of maternal sounds during the second stage of labor. | Experienced obstetric nurse and midwives indicate they can differentiate among sounds indicating that a woman is (a) beginning to manifest the effort to bear down, (b) experiencing pain, or (c) frightened. This study examined the acoustical properties of work/effort, childlike, and out-of-control utterances to determin... | ['Adult', 'Cues', 'Female', 'Humans', 'Labor, Obstetric', 'Nurse Midwives', 'Nursing Assessment', 'Nursing Evaluation Research', 'Obstetric Nursing', 'Pregnancy', 'Psychoacoustics', 'Sound Spectrography', 'Verbal Behavior', 'Videotape Recording'] | 8,439,179 | [['M01.060.116'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['M01.526.485.650.648.762', 'N02.360.650.648.762'], ['N04.590.233.508.480'], ['H01.770.644.145.390.432', 'H02.478.395.432', 'N04.590.233.508.613.432'], ['H02.478.676.570', 'N02.421.533.571'], ['G08.686.784.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Central motor pathway evaluation using magnetic coil stimulation in hereditary motor and sensory neuropathy type I (HMSN type I, Charcot-Marie-Tooth disease). | Central Motor Conduction Time (CMCT) was investigated in 18 patients (5 m, 13 f; age range: 11-69 yrs) with clinical and electrophysiological features of HMSN type I, using Magnetic Coil (MC) stimulation. No one exhibited clinically pyramidal signs. Brain stimulation Motor Evoked Potentials (MEPs), recorded monolateral... | ['Adolescent', 'Adult', 'Aged', 'Arm', 'Charcot-Marie-Tooth Disease', 'Child', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Leg', 'Magnetics', 'Male', 'Middle Aged', 'Motor Neurons', 'Neural Conduction', 'Spinal Cord'] | 9,522,263 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A01.378.800.075'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['M01.060.406'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B0... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Overactivation of NR2B-containing NMDA receptors through entorhinal-hippocampal connection initiates accumulation of hyperphosphorylated tau in rat hippocampus after transient middle cerebral artery occlusion. | Middle cerebral artery occlusion (MCAO) induces secondary damages in the hippocampus that is remote from primary ischemic regions. Tau hyperphosphorylation is an important risk for neurodegenerative diseases. Increased tau phosphorylation has been identified in ischemic cortex, but little is known regarding the changes... | ['Animals', 'Blotting, Western', 'Entorhinal Cortex', 'Functional Laterality', 'Hippocampus', 'Infarction, Middle Cerebral Artery', 'Male', 'Neural Pathways', 'Phosphorylation', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate', 'tau Proteins'] | 25,903,928 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211.180.590.750.225', 'A08.186.211.180.710.225', 'A08.186.211.200.885.287.500.382.750.225', 'A08.186.211.200.885.287.500.620.562', 'A08.186.211.200.885.287.500.814.695.374', 'A08.186.211.200.885.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the flagellin (hag) gene of alkalophilic Bacillus sp. C-125. | Motility of the alkalophilic Bacillus sp. C-125, a flagellate bacterium, was demonstrated to be Na(+)- and pH-dependent. Flagellin protein from this strain was purified to homogeneity and the N-terminal sequence determined. Using the hag gene of Bacillus subtilis as a probe, the hag gene of Bacillus sp. C-125 was ident... | ['Amino Acid Sequence', 'Bacillus', 'Base Sequence', 'Cell Movement', 'Flagellin', 'Genes, Bacterial', 'Hydrogen-Ion Concentration', 'Molecular Sequence Data', 'Restriction Mapping', 'Sequence Homology, Amino Acid', 'Sodium'] | 1,479,346 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.198', 'G07.568.500.180'], ['D12.776.097.380'], ['G05.360.340.024.340.364.249', 'G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Disturbances in hypothalamo pituitary adrenal and thyroid axis identify different sleep EEG patterns in major depressed patients. | This study was aimed at investigating the relationships between sleep EEG abnormalities and hypothalamo pituitary adrenal (HPA) and hypothalamo pituitary thyroid (HPT) disturbances in major depressive disorder. Post dexamethasone (DXM) cortisol levels and the dual TSH response to 08:00 h and 23:00 h TRH administration ... | ['Administration, Topical', 'Adult', 'Anti-Inflammatory Agents', 'Cluster Analysis', 'Depressive Disorder, Major', 'Dexamethasone', 'Electroencephalography', 'Female', 'Glucocorticoids', 'Humans', 'Hypothalamo-Hypophyseal System', 'Male', 'Middle Aged', 'Pituitary-Adrenal System', 'Principal Component Analysis', 'Psych... | 12,482,464 | [['E02.319.267.120'], ['M01.060.116'], ['D27.505.954.158'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['F03.600.300.375'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['E01.370.376.300', 'E01.370.405.245'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.98... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Time varying networks and the weakness of strong ties. | In most social and information systems the activity of agents generates rapidly evolving time-varying networks. The temporal variation in networks' connectivity patterns and the ongoing dynamic processes are usually coupled in ways that still challenge our mathematical or computational modelling. Here we analyse a mobi... | ['Algorithms', 'Cell Phone', 'Community Networks', 'Humans', 'Information Dissemination', 'Models, Theoretical', 'Social Networking'] | 24,510,159 | [['G17.035', 'L01.224.050'], ['L01.178.847.698.300'], ['I01.880.853.500.300', 'L01.313.500.750.300.184', 'N02.421.143.202'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['E05.599'], ['L01.143.910']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Optimizing therapeutic timing in patients undergoing mastectomy through use of the Tiloop® synthetic mesh: single-step surgery. | Patients undergoing mastectomy for breast cancer have to face a long and elaborated therapeutic path, very often burdened by reoperation to replace the temporary expander, used to enlarge the submuscular pouch, with a definitive implant. Postoperative planning represents a critical moment of care, as it requires the in... | ['Aged', 'Breast Implantation', 'Breast Implants', 'Breast Neoplasms', 'Female', 'Humans', 'Mastectomy', 'Middle Aged', 'Time Factors', 'Treatment Outcome'] | 23,606,695 | [['M01.060.116.100'], ['E02.218.565.210', 'E04.650.210', 'E04.680.500.210'], ['E07.695.140'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466'], ['M01.060.116.630'], ['G01.910.857'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association between topical prostaglandin analog use and development of choroidal neovascular membranes in patients with concurrent glaucoma and age-related macular degeneration. | PURPOSE: Matrix metalloproteinases (MMPs) are a family of enzymes that act to degrade extracellular matrix (ECM) molecules, such as collagen, elastin, and gelatin. The glaucoma medication latanoprost, and possibly other topical prostaglandin analogs, increase uveoscleral outflow and lower intraocular pressure (IOP) in ... | ['Administration, Topical', 'Aged, 80 and over', 'Antihypertensive Agents', 'Choroidal Neovascularization', 'Glaucoma', 'Humans', 'Macular Degeneration', 'Medical Records', 'Prostaglandins, Synthetic', 'Retrospective Studies', 'Risk Factors'] | 16,722,800 | [['E02.319.267.120'], ['M01.060.116.100.080'], ['D27.505.954.411.162'], ['C11.941.160.244', 'C23.550.589.500.145'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['D10.251.355.255.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sunscreen products impair the early developmental stages of the sea urchin Paracentrotus lividus. | Marine ecosystems are increasingly threatened by the release of personal care products. Among them, sunscreens are causing concern either for the effects on skin protection from UV radiation and for the potential impacts on marine life. Here, we assessed the UVA protective efficacy of three sunscreens on human dermal f... | ['Animals', 'Cell Survival', 'Cells, Cultured', 'Embryonic Development', 'Europe', 'Fibroblasts', 'Humans', 'Paracentrotus', 'Reactive Oxygen Species', 'Sunscreening Agents', 'Ultraviolet Rays', 'United States', 'Water Pollutants, Chemical'] | 28,798,318 | [['B01.050'], ['G04.346'], ['A11.251'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['Z01.542'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.408.578.600'], ['D01.339.431', 'D01.650.775'], ['D27.505.696.706.776.800', 'D27.505.954.444.695', 'D27.720.269.800', 'D27.720.799.763.764']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Pentametric distribution of platelet monoamine oxidase activity. | The distribution of catalytic activity of platelet monoamine oxidase (MAO) with both tryptamine and phenylethylamine as substrates was examined in 1,129 Swedish men at age 18 years. A mixture of five components was needed to describe the distribution, even when the original scale was transformed to remove skewness. The... | ['Adolescent', 'Alleles', 'Blood Platelets', 'Female', 'Genotype', 'Humans', 'Male', 'Monoamine Oxidase', 'Phenethylamines', 'Reference Values', 'Substrate Specificity', 'Sweden', 'Tryptamines', 'United States'] | 3,862,145 | [['M01.060.057'], ['G05.360.340.024.340.030'], ['A11.118.188', 'A15.145.229.188'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.664.750'], ['D02.092.471.683'], ['E05.978.810'], ['G02.111.835'], ['Z01.542.816.500'], ['D02.092.211.215.801', 'D03.633.100.473.914'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Predictors of progression from normoalbuminuria to microalbuminuria in NIDDM. | OBJECTIVE: Our objective was to establish the clinical, genetic, metabolic, and immunologic risk factors for the progression of the albumin excretion rate (AER) in normoalbuminuric NIDDM patients.RESEARCH DESIGN AND METHODS: We recruited 108 NIDDM patients with normal AER after a diabetes duration of 9 years to partici... | ['Adult', 'Aged', 'Albuminuria', 'Biomarkers', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Disease Progression', 'Female', 'Histocompatibility Testing', 'Humans', 'Male', 'Middle Aged', 'Risk Factors'] | 9,802,746 | [['M01.060.116'], ['M01.060.116.100'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D23.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['C23.550.291.656'], ['E01.370.225.812... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template. | Genetic mutations or engineered nucleases that disrupt the HIV co-receptor CCR5 block HIV infection of CD4(+) T cells. These findings have motivated the engineering of CCR5-specific nucleases for application as HIV therapies. The efficacy of this approach relies on efficient biallelic disruption of CCR5, and the abilit... | ['Adult', 'Antigens, CD34', 'CD3 Complex', 'Cells, Cultured', 'DNA Repair', 'Deoxyribonucleases', 'Dependovirus', 'Genetic Loci', 'Genetic Therapy', 'Green Fluorescent Proteins', 'Hematopoietic Stem Cells', 'Humans', 'RNA Editing', 'Receptors, Antigen, T-Cell', 'Receptors, CCR5', 'T-Lymphocytes'] | 26,424,571 | [['M01.060.116'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['A11.251'], ['G02.111.222', 'G05.219'], ['D08.811.277.352.335'], ['B04.280.580.650.170'], ['G05.360.340.024.380'], ['E02.095.301', 'E05.393.420.301'], ['D12.776.532.265'], ['A11.148.378', 'A11.872.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
500 MHz 1H n.m.r. of oligosaccharides of N-acetyl-lactosamine-type released from human erythrocyte glycopeptides by endo-beta-galactosidase. | 500 MHz 1H n.m.r. spectroscopy has been used in structural studies of three linear and five branched oligosaccharides of N-acetyl-lactosamine-type that were released from desialylated blood group O erythrocyte glycopeptides by treatment with the endo-beta-galactosidase of Bacteroides fragilis followed by reduction. The... | ['Chemical Phenomena', 'Chemistry', 'Erythrocytes', 'Glycopeptides', 'Glycoside Hydrolases', 'Humans', 'Magnetic Resonance Spectroscopy', 'Oligosaccharides', 'Sugar Alcohols', 'beta-Galactosidase'] | 3,128,279 | [['G02'], ['H01.181'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D09.400.420', 'D12.644.233'], ['D08.811.277.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['D09.698.629'], ['D02.033.800', 'D09.853'], ['D08.811.277.450.410.100']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Distal interphalangeal joint bony dimensions related to headless compression screw sizes. | PURPOSE: To determine the radiographic dimensions of the distal interphalangeal (DIP) joint and to compare these measurements with commonly used headless compression screws.METHODS: Using standard posteroanterior and lateral radiographs of the hand, we measured the dimensions of the distal and middle phalanges in 60 in... | ['Arthrodesis', 'Bone Screws', 'Female', 'Finger Joint', 'Humans', 'Male', 'Prosthesis Design', 'Prosthesis Failure', 'Radiography', 'Reproducibility of Results', 'Risk Factors'] | 24,751,471 | [['E04.555.100'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A02.835.583.405.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.320.550', 'E07.695.680'], ['C23.550.767.865', 'E05.325.771'], ['E01.370.350.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evidence of DNA transfer through F-pilus channels during Escherichia coli conjugation. | The mechanism of DNA transfer from Escherichia coli ( E. coli) Hfr donor strain AT2453 to recipient strain AB1157 during the conjugation process has been investigated by liquid atomic force microscopy (AFM). With the success of immobilizing both E. coli strains on gelatin-treated glass under aqueous solution, the F-pil... | ['Antibodies', 'DNA, Single-Stranded', 'Escherichia coli', 'Microscopy, Atomic Force'] | 18,522,439 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E01.370.350.515.666.400', 'E05.595.666.400']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two pathways for RNase E action in Escherichia coli in vivo and bypass of its essentiality in mutants defective for Rho-dependent transcription termination. | The endonuclease RNase E of Escherichia coli is essential for viability, but deletion of its C-terminal half (CTH) is not lethal. RNase E preferentially acts on 5'-monophosphorylated RNA whose generation from primary transcripts is catalysed by RppH, but ÄRppH strains are viable. Here we show that the RNase E-ÄCTH ÄRpp... | ['Acid Anhydride Hydrolases', 'Endoribonucleases', 'Escherichia coli', 'Escherichia coli Proteins', 'Mutation', 'Peptide Elongation Factors', 'Protein Structure, Tertiary', 'RNA Stability', 'RNA, Bacterial', 'Rho Factor', 'Transcription Factors', 'Transcription, Genetic'] | 22,026,368 | [['D08.811.277.040'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.365.590'], ['D12.776.835.700'], ['G02.111.570.820.709.610'], ['G02.111.780'], ['D13.444.735.473'], ['D12.776.930.785'], ['D12.776.930'], ['G02.111.873', 'G05.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rational design, synthesis and biological evaluation of 1,3,4-oxadiazole pyrimidine derivatives as novel pyruvate dehydrogenase complex E1 inhibitors. | On the basis of previous study on 2-methylpyrimidine-4-ylamine derivatives I, further synthetic optimization was done to find potent PDHc-E1 inhibitors with antibacterial activity. Three series of novel pyrimidine derivatives 6, 11 and 14 were designed and synthesized as potential Escherichia coli PDHc-E1 inhibitors by... | ['Anti-Bacterial Agents', 'Antifungal Agents', 'Cyanobacteria', 'Dose-Response Relationship, Drug', 'Drug Design', 'Enzyme Inhibitors', 'Escherichia coli', 'Fungi', 'Molecular Structure', 'Oxadiazoles', 'Pyrimidines', 'Pyruvate Dehydrogenase (Lipoamide)', 'Structure-Activity Relationship'] | 26,972,920 | [['D27.505.954.122.085'], ['D27.505.954.122.136'], ['B03.280', 'B03.440.475.100'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.300'], ['G02.111.570', 'G02.466'], ['D03.383.12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Secondary amyloidosis in Crohn's disease]. | Amyloidosis is a clinical entity that results from the deposition of an extracellular protein material that causes disruption in the normal architecture of multiple organs and tissues, and impairs their function. Secondary amyloidosis is a rare but serious complication that may worsen the prognosis of patients with can... | ['Adult', 'Amyloidosis', 'Crohn Disease', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged'] | 19,222,341 | [['M01.060.116'], ['C18.452.845.500'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Advanced determination of the spatial gradient of human health risk and ecological risk from exposure to As, Cu, Pb, and Zn in soils near the Ventanas Industrial Complex (Puchuncav?, Chile). | The townships of Puchuncav? and Quintero, on the coast of central Chile, have soils contaminated by atmospheric deposition of sulfur dioxide and trace elements from the nearby Ventanas Industrial Complex. The purpose of this study was to evaluate potential human health and ecological risks, by determining the spatial d... | ['Air Pollutants', 'Arsenic', 'Child', 'Child, Preschool', 'Chile', 'Copper', 'Environmental Exposure', 'Environmental Monitoring', 'Humans', 'Industry', 'Infant', 'Lead', 'Metals, Heavy', 'Risk Assessment', 'Soil', 'Soil Pollutants', 'Spatial Analysis', 'Zinc'] | 31,859,123 | [['D27.888.284.101'], ['D01.268.513.249'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.757.235'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['M01.060.703'], ['D01.268.556.4... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Fatigue resistance of inspiratory muscles in patients with severe mitral valve stenosis]. | The strength and endurance of the inspiratory muscles was assessed in 14 patients with severe mitral valve stenosis uncomplicated by other diseases. Strength was evaluated measuring the maximal static inspiratory pressure (MIP). Endurance was measured using a two minute weight incremental test, to obtain the maximal su... | ['Adult', 'Airway Resistance', 'Anthropometry', 'Dyspnea', 'Female', 'Humans', 'Inspiratory Capacity', 'Intermittent Positive-Pressure Ventilation', 'Male', 'Middle Aged', 'Mitral Valve Stenosis', 'Respiratory Muscles', 'Spirometry', 'Vital Capacity'] | 8,235,165 | [['M01.060.116'], ['E01.370.386.700.050', 'G09.772.060'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C08.618.326', 'C23.888.852.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485.750.900.350', 'G09.772.850.970.500'], ['E02.041.625.790.550', 'E02.880.820.790.550'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The neuroendocrine response of luteinizing hormone to estrogen administration in heterosexual, homosexual, and transsexual subjects. | The neuroendocrine response of LH to estrogen administration may be related to sexual dimorphism of the brain, and therefore, homosexual and especially transsexual individuals may differ from heterosexual individuals in their responses. This study failed to find such differences among groups of female heterosexuals, ho... | ['Adult', 'Chorionic Gonadotropin', 'Estradiol', 'Estrogens, Conjugated (USP)', 'Female', 'Gonadotropin-Releasing Hormone', 'Homosexuality', 'Humans', 'Luteinizing Hormone', 'Male', 'Testosterone', 'Transsexualism'] | 3,016,021 | [['M01.060.116'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.334.851.437.988'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Face, content, and construct validities of inanimate intestinal anastomoses simulation. | PURPOSE: Surgical simulation modules for "open" surgery are limited and not well studied or validated. Available simulation modules use either synthetic material, which is convenient but may not mimic what is observed or felt in the operating room, or live animal laboratories, which can simulate human tissue but are co... | ['Anastomosis, Surgical', 'Animals', 'General Surgery', 'Intestines', 'Surgical Stapling', 'Suture Techniques', 'Swine', 'Teaching'] | 18,063,271 | [['E04.035'], ['B01.050'], ['H02.403.810.300'], ['A03.556.124'], ['E04.987.775.800'], ['E04.987.775'], ['B01.050.150.900.649.313.500.880'], ['I02.903']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Intermediate Levels of Bacillus subtilis CodY Activity Are Required for Derepression of the Branched-Chain Amino Acid Permease, BraB. | The global transcriptional regulator, CodY, binds strongly to the regulatory region of the braB gene, which encodes a Bacillus subtilis branched-chain amino acid (BCAA) permease. However, under conditions that maximize CodY activity, braB expression was similar in wild-type and codY null mutant cells. Nonetheless, expr... | ['Amino Acid Transport Systems', 'Amino Acids, Branched-Chain', 'Bacillus subtilis', 'Bacterial Proteins', 'Binding Sites', 'DNA-Binding Proteins', 'Gene Expression Regulation, Bacterial', 'Promoter Regions, Genetic', 'Protein Binding', 'Transcription Factors'] | 26,473,603 | [['D12.776.157.530.200', 'D12.776.543.585.200'], ['D12.125.070'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['G02.111.570.120'], ['D12.776.260'], ['G05.308.300'], ['G02.111.570.080.689.675', 'G05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening of Hungarian cattle herds for Mycoplasma mycoides subspecies mycoides small colony infection with negative results. | At abattoirs and farms, 1248 sera were collected from animals representing 121 farms, and examined by complement fixation test using Mycoplasma mycoides subspecies mycoides small colony type (MmmSC) antigen. All sera were negative except seven from four farms, giving ++ reactions in the serum dilution of 1:10. On retes... | ['Animals', 'Cattle', 'Cattle Diseases', 'Complement Fixation Tests', 'Hungary', 'Lung', 'Mycoplasma mycoides', 'Pleuropneumonia, Contagious', 'Polymerase Chain Reaction'] | 11,402,655 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E01.370.225.812.735.150', 'E05.200.812.735.150', 'E05.478.594.760.150'], ['Z01.542.248.495'], ['A04.411'], ['B03.440.860.580.553.553.585'], ['C01.150.252.400.610.610.717', 'C22.717'], ['E05.393.620.500']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
FaceTime validation study: Low-cost streaming video for cytology adequacy assessment. | BACKGROUND: Adequacy assessment for fine-needle aspiration procedures is a standard of care in large medical centers. Although the benefits of this approach include higher adequacy rates with fewer passes, it costs cytopathologist time and affects other clinical responsibilities. The objective of the current study was ... | ['Biopsy, Fine-Needle', 'Humans', 'Retrospective Studies', 'Smartphone', 'Telepathology', 'Video Recording'] | 26,491,941 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Lights, camera, action… spotlight on trauma video review: an underutilized means of quality improvement and education. | BACKGROUND: Trauma video review (TVR) is an effective method of quality improvement and education. The objective of this study was to determine TVR practices in the United States and use of TVR for quality improvement and education.METHODS: Adult and pediatric trauma centers identified by the American College of Surgeo... | ['Chi-Square Distribution', 'Education, Medical, Graduate', 'Humans', 'Internship and Residency', 'Pediatrics', "Practice Patterns, Physicians'", 'Quality Improvement', 'Surveys and Questionnaires', 'Trauma Centers', 'Traumatology', 'United States', 'Videotape Recording'] | 20,944,509 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['H02.403.670'], ['N04.590.374.577', 'N05.300.625'], ['J01.293.754', 'N04.761.744'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Information Sc... | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Aberrant NKG2D expression with IL-17 production of CD4+ T subsets in patients with type 2 diabetes. | Type 2 diabetes (T2D) is a systemic inflammatory disease. Although the natural killer group 2, member D (NKG2D) receptor, was not expressed normally on CD4+ T cells, the aberrant expression was found in pathological conditions such as in auto-immune diseases. However, the involvement of NKG2D in pathogenesis of T2D is ... | ['Adult', 'Antibodies, Monoclonal', 'CD4-Positive T-Lymphocytes', 'Cell Proliferation', 'Cells, Cultured', 'Diabetes Mellitus, Type 2', 'Female', 'Gene Expression', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Immunophenotyping', 'Interleukin-17', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'NK Cell Lectin-L... | 27,168,217 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['C18.452.394.750.149', 'C19.246.300'], ['G05.297'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Fractionation of phycobilisomes from the blue-green alga Nostoc muscorum]. | Phycobilisomes (PBS) isolated from Nostoc muscorum contain eight spectral forms of phycobiliproteins. PBS partially dissociated by osmotic or temperature shock, were separated into 42S and 34S particles by centrifugation in sucrose density gradient. The 42S particles are enriched with phycocyanin, the 34S ones--with al... | ['Cell Fractionation', 'Centrifugation, Density Gradient', 'Cyanobacteria', 'Light-Harvesting Protein Complexes', 'Phycobilisomes', 'Phycocyanin', 'Phycoerythrin', 'Pigments, Biological', 'Plant Proteins', 'Spectrophotometry'] | 6,423,967 | [['E05.242.251'], ['E05.181.724.336', 'E05.196.941.336'], ['B03.280', 'B03.440.475.100'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', 'D12.776.765.199.750.750.490'], ['A11.284.149.165.695', 'D05.500.562.488.490.500', 'D08.811.600.710.490.500'], ['D05.500.562.488.490.500.500.755', 'D08.811.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Housing preferences and perceptions of health and functioning among homeless mentally ill persons. | OBJECTIVE: Most homeless persons who have received services for serious mental illness want to live on their own, but mental health professionals usually recommend group housing. This study examined the relationship between the types of residential arrangements preferred by homeless mentally ill persons and their demog... | ['Activities of Daily Living', 'Adult', 'Boston', 'Choice Behavior', 'Decision Making', 'Female', 'Group Homes', 'Homeless Persons', 'Humans', 'Male', 'Mental Competency', 'Mental Disorders', 'Middle Aged', 'Public Housing', 'Quality of Life', 'Schizophrenia', 'Schizophrenic Psychology', 'Social Support', 'Urban Popula... | 8,689,368 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['F02.463.785.373.346'], ['F02.463.785.373'], ['J03.775.375', 'N02.278.825.375'], ['M01.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.590', 'F02.410', 'I01.880.604.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Dihydroartemisinin inhibits proliferation of pancreatic cancer JF-305 cells by regulating expression of apoptosis related proteins and production of reactive oxygen species]. | To investigate the effect of dihydroartemisinin on apoptosis of human pancreatic cancer cell line JF-305 and the role of reactive oxygen species(ROS) in the apoptosis of JF-305 cells induced by dihydroartemisinin. MTT assays were used to detect effect of different concentrations of dihydroartemisinin on cells prolifera... | ['Apoptosis', 'Artemisinins', 'Caspase 3', 'Caspase 9', 'Cell Proliferation', 'Cytochromes c', 'Humans', 'Pancreatic Neoplasms', 'Proto-Oncogene Proteins c-bcl-2', 'Reactive Oxygen Species', 'bcl-2-Associated X Protein'] | 29,139,274 | [['G04.146.954.035'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126.550.9... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The evolution of the new permeability pathways in Plasmodium falciparum--infected erythrocytes--a kinetic analysis. | Malaria parasites demonstrably increase the permeability of the membrane of the erythrocyte in which they develop and propagate. New permeability pathways (NPPs) generated by parasite activity and identified in the erythrocyte membrane are held responsible for these changes. Here, we present a novel analysis of hemolys... | ['Animals', 'Cell Membrane Permeability', 'Centrifugation, Density Gradient', 'Erythrocyte Membrane', 'Erythrocytes', 'Hemoglobins', 'Hemolysis', 'Humans', 'Indicators and Reagents', 'Kinetics', 'Nonlinear Dynamics', 'Plasmodium falciparum', 'Povidone', 'Regression Analysis', 'Silicon Dioxide', 'Sorbitol'] | 16,707,126 | [['B01.050'], ['G03.143.335', 'G04.175'], ['E05.181.724.336', 'E05.196.941.336'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D12.776.124.400', 'D12.776.422.316.762'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
6-Aza-2'-deoxy-2'-arabinofluorouridine, a 2'-deoxyribonucleoside with an N-sugar conformation in the solid state and in solution. | In the title compound, 2-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione, C(8)H(10)FN(3)O(5), the torsion angle of the N-glycosylic bond is anti [chi = -125.37 (13) degrees]. The furanose moiety adopts the N-type sugar pucker ((3)T(2)), with P = 359.2 degrees and tau(m) = 31.4 degrees. The co... | ['Carbohydrate Conformation', 'Carbohydrates', 'Models, Molecular', 'Nuclear Magnetic Resonance, Biomolecular', 'Solutions'] | 15,579,973 | [['G02.111.570.820.235'], ['D09'], ['E05.599.595'], ['E05.196.867.519.550'], ['D26.776']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study of a population of Biomphalaria tenagophila (Orbigny, 1835) and of schistosomiasis transmission in "Alto da Boa Vista", Rio de Janeiro. | The present study was performed using data from a Biomphalaria tenagophila population located in a watercress garden in the Alto da Boa Vista region representing an isolated focal point of schistosomiasis in the city of Rio de Janeiro. The density and age structure of this B. tenagophila population and its rate of infe... | ['Animals', 'Biomphalaria', 'Brazil', 'Ecology', 'Humans', 'Population Density', 'Schistosoma mansoni', 'Schistosomiasis mansoni', 'Seasons', 'Vegetables'] | 2,520,827 | [['B01.050'], ['B01.050.500.644.400.750.185'], ['Z01.107.757.176'], ['H01.158.273.248', 'H01.277.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.224.600', 'N06.850.505.400.600'], ['B01.050.500.500.736.715.770.680.700'], ['C01.610.335.865.859.576', 'C01.920.922.576'], ['G01.910.645.661', 'G16.500.275.071.5... | ['Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
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