Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Differential role of GABAA and GABAB receptors in two distinct output stations of the rat striatum: studies on the substantia nigra pars reticulata and the globus pallidus. | The role of GABA(A) and GABA(B) receptors in the substantia nigra pars reticulata and the globus pallidus in turning behaviour of rats was studied. Unilateral injection of the GABA(A) receptor agonist muscimol (25 and 50 ng) into the substantia nigra pars reticulata elicited contralateral pivoting, namely tight head-to... | ['Animals', 'Baclofen', 'Bicuculline', 'Corpus Striatum', 'Dose-Response Relationship, Drug', 'GABA Agonists', 'GABA Antagonists', 'GABA-A Receptor Agonists', 'GABA-A Receptor Antagonists', 'GABA-B Receptor Agonists', 'GABA-B Receptor Antagonists', 'Globus Pallidus', 'Male', 'Motor Activity', 'Muscimol', 'Phosphinic Ac... | 20,132,872 | [['B01.050'], ['D02.241.081.114.500.350.100'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['A08.186.211.200.885.287.249.487'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.625.240.200', 'D27.505.696.577.240.200'], ['D27.505.519.625.240.300', 'D27.505.696.577.240.300'], ['D27.505.519.625.240.200.500', 'D27... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epithelial injury, inflammation, and repair in the hamster lung following intratracheal instillation of enzyme-generated oxidants. | Oxidant-induced inflammatory and morphologic changes evoked by intratracheally instilled glucose, active glucose oxidase, and lactoperoxidase in hamsters are described. Similar solutions containing heat-denatured (DE) glucose oxidase served as a control treatment. During the 7-week post-treatment period, animals were s... | ['Administration, Oral', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Cricetinae', 'Epithelium', 'Free Radicals', 'Glucose Oxidase', 'Lung', 'Male', 'Mesocricetus', 'Oxygen', 'Pneumonia', 'Trachea', 'Wound Healing'] | 1,860,455 | [['E02.319.267.100'], ['B01.050'], ['E05.927.100.500'], ['B01.050.150.900.649.313.992.635.075.250'], ['A10.272'], ['D01.339', 'D02.389'], ['D08.811.682.047.239'], ['A04.411'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['D01.268.185.550', 'D01.362.670'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['A04.889'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Malignant memories: PTSD in children and adults after a school shooting. | Sixty-four children and 66 adults were screened for post-traumatic stress disorder 6 to 14 months after a school shooting. Although there were no differences in overall frequencies of DSM-III-R diagnoses or cluster endorsements, there were developmental influences. Post-traumatic stress disorder was associated more wit... | ['Adult', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Illinois', 'Male', 'Mental Recall', 'Schools', 'Stress Disorders, Post-Traumatic', 'Violence', 'Wounds, Gunshot'] | 1,757,443 | [['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.350', 'Z01.107.567.875.510.350'], ['F02.463.425.540.641'], ['I02.783', 'J03.832'], ['F03.950.750.500'], ['I01.198.240.856',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Genetics and expression analysis of the specificity protein 4 gene (SP4) in patients with Alzheimer's disease and frontotemporal lobar degeneration. | Transcription factor Sp4 (Specificity protein 4) levels are increased in the brain of patients with Alzheimer's disease (AD), and Sp4 colocalizes with neurofibrillary tangles. Moreover, SP4 is a susceptibility gene for bipolar disorder and schizophrenia, which share many clinical features with frontotemporal lobar dege... | ['Aged', 'Female', 'Frontotemporal Lobar Degeneration', 'Gene Expression Regulation', 'Genotype', 'Humans', 'Male', 'Sp4 Transcription Factor'] | 22,614,877 | [['M01.060.116.100'], ['C10.228.140.380.266', 'C10.574.950.300', 'C18.452.845.800.300', 'F03.615.400.380'], ['G05.308'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.260.522.750.875', 'D12.776.930.375.750.875']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Health care and AIDS. | The acquired immune deficiency syndrome (AIDS) is a harbinger for change in health care. There are many powerful forces poised to transform the industrialized health care structure of the twentieth century, and AIDS may act as either a catalyst or an amplifier for these forces. AIDS could, for example, swamp local reso... | ['Acquired Immunodeficiency Syndrome', 'Community Participation', 'Delivery of Health Care', 'Forecasting', 'Health Policy', 'Humans', 'Models, Theoretical', 'Policy Making', 'Politics', 'Research', 'United States'] | 10,119,289 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['N02.421.143.212', 'N03.540.245.360'], ['N04.590.374', 'N05.300'], ['I01.320'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428... | ['Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Evaluation of prenatal and postnatal diagnostic criteria for twin anemia-polycythemia sequence. | OBJECTIVE: The aim of this study is to analyze the relevance of the prenatal and postnatal diagnostic parameters of twin anemia-polycythemia sequence (TAPS).METHODS: Diagnostic data of all cases of TAPS followed in our institution between 2006 and 2013 were reviewed. Statistical analyses were conducted using Bayesian m... | ['Adult', 'Anemia, Neonatal', 'Bayes Theorem', 'Blood Flow Velocity', 'Cohort Studies', 'Female', 'Fetofetal Transfusion', 'Gestational Age', 'Hemoglobins', 'Humans', 'Infant, Newborn', 'Middle Cerebral Artery', 'Polycythemia', 'Pregnancy', 'Pregnancy, Twin', 'Prospective Studies', 'Twins, Monozygotic', 'Ultrasonograph... | 25,484,182 | [['M01.060.116'], ['C15.378.071.363', 'C16.614.053'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C15.378.071.363.344', 'C16.614.053.344'], ['G07.345.500.325.23... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exploring the complexity: the interplay between the angiotensin-converting enzyme insertion/deletion polymorphism and the sympathetic response to hemodialysis. | Patients on hemodialysis (HD) are at increased risk for arrhythmias and sudden cardiac death. Autonomic nervous system (ANS) dysfunction seems to participate in the arrhythmogenic process. Genetic factors have an impact on ANS modulation, but the specific role of the insertion/deletion (I/D) polymorphism in the gene fo... | ['Adult', 'Aged', 'Body Composition', 'Cross-Sectional Studies', 'Female', 'Gene Frequency', 'Heart', 'Heart Rate', 'Heterozygote', 'Homozygote', 'Humans', 'INDEL Mutation', 'Male', 'Middle Aged', 'Peptidyl-Dipeptidase A', 'Renal Dialysis', 'Renal Insufficiency, Chronic', 'Sympathetic Nervous System', 'Time Factors', '... | 29,949,384 | [['M01.060.116'], ['M01.060.116.100'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G05.330'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G05.380.383'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tea catechin, epigallocatechin-3-gallate suppresses myosin II regulatory light chain phosphorylation. | Phosphorylation of myosin II regulatory light chain (MRLC) is critical event for many cellular processes including muscle contraction, mytosis, migration, and exocytosis. Epigallocatechin-3-O-gallate (EGCG) is a major polyphenolic compound of green tea and has various physiological functions. We found that EGCG disrupt... | ['Antioxidants', 'Catechin', 'HeLa Cells', 'Humans', 'Myosin Light Chains', 'Phosphorylation', 'Stress, Mechanical', 'Tea'] | 15,630,232 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.730.475.200'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Weight-bearing-induced changes in the microtopography and structural stiffness of human skin in vivo following immobility periods. | Pressure ulcers (PUs) are injuries to the skin and underlying tissues, caused by sustained deformations and occur frequently in aged patients. Skin microtopography and stiffness affect the interaction of skin with contact surfaces contributing to PU development. We simulated immobility in 20 healthy females (mean age 6... | ['Aged', 'Elasticity', 'Female', 'Humans', 'Immobilization', 'Male', 'Pressure Ulcer', 'Regional Blood Flow', 'Sacrum', 'Skin', 'Skin Aging', 'Skin Physiological Phenomena', 'Weight-Bearing', 'Wound Healing'] | 25,682,694 | [['M01.060.116.100'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.472'], ['C17.800.893.665'], ['G09.330.100.780'], ['A02.835.232.834.717'], ['A17.815'], ['G13.750.804'], ['G13.750'], ['G01.374.965'], ['G16.762.891']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessment of long-term omalizumab treatment in patients with severe allergic asthma long-term omalizumab treatment in severe asthma. | OBJECTIVE: Several clinical studies have demonstrated the effectiveness of omalizumab in patients with severe allergic asthma but the treatment period has always been relatively short (4-12 months). In the literature, there are a few data about the long-term omalizumab therapy. We aimed to assess the long-term clinical... | ['Adult', 'Anti-Allergic Agents', 'Anti-Asthmatic Agents', 'Antibodies, Anti-Idiotypic', 'Antibodies, Monoclonal, Humanized', 'Asthma', 'Emergency Service, Hospital', 'Female', 'Forced Expiratory Volume', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Omalizumab', 'Quality of Life', 'Treatment Outcome'] | 23,557,459 | [['M01.060.116'], ['D27.505.954.016'], ['D27.505.954.796.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Dramatic promotion of wound healing using a recombinant human-like collagen and bFGF cross-linked hydrogel by transglutaminase. | The basic fibroblast growth factor (bFGF) plays an important role in the wound repair process. However, lacking of better biomaterials to carry bFGF still is a challenge in skin repair and regeneration. In this study, the human-like collagen (HLC) cross-linked with transglutaminase (TG) to fabricate a HLC/TG hydrogel t... | ['Animals', 'Biocompatible Materials', 'Cell Line', 'Collagen', 'Cross-Linking Reagents', 'Drug Carriers', 'Fibroblast Growth Factor 2', 'Humans', 'Hydrogels', 'Mice', 'Recombinant Proteins', 'Transglutaminases', 'Wound Healing'] | 31,411,556 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A11.251.210'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D27.720.470.410.210'], ['D26.255.260', 'E02.319.300.380'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Heart rate variability in patients with neurocardiogenic syncopes]. | AIM: To investigate chronotropic heart regulation and prognostic significance of heart rate variability (HRV) in patients with neurocardiogenic syncopes (NCS).MATERIAL AND METHODS: A total of 90 patients (25 healthy controls and 65 patients with documented HRV, mean age 33.9 +/- 17.4 years) were divided into 3 groups d... | ['Adult', 'Case-Control Studies', 'Heart Rate', 'Humans', 'Parasympathetic Nervous System', 'Posture', 'Signal Processing, Computer-Assisted', 'Syncope, Vasovagal', 'Tilt-Table Test'] | 19,537,592 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.050.600'], ['G11.427.695'], ['L01.224.800'], ['C10.177.575.600.800', 'C10.597.606.358.800.600.500', 'C23.888.592.604.359... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Prevention of adverse reactions of antituberculous drugs in pulmonary tuberculosis in patients with different genetic background]. | A hundred and sixty-seven patients with pulmonary tuberculosis were examined to study the genetic predisposition to adverse reactions (AR) from chemical drugs. The phenotype of haptoglobin carriage, the type of, the activity of the enzyme glucose-6-phosphate dehydrogenase inactivation were used as a genetic marker. If ... | ['Antitubercular Agents', 'Combined Modality Therapy', 'Genetic Markers', 'Genotype', 'Humans', 'Phytotherapy', 'Tuberculosis, Pulmonary'] | 12,899,021 | [['D27.505.954.122.085.255'], ['E02.186'], ['D23.101.387', 'G05.695.450'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.755'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organization of stratum corneum lipids in relation to permeability: influence of sodium lauryl sulfate and preheating. | The role of the structural organization of intercorneocyte lipids in the barrier function of human stratum corneum was evaluated by treatment with heat and sodium lauryl sulfate. Measurement of transepidermal water loss in treated samples was used to quantify variations in stratum corneum permeability. Thermodynamic tr... | ['Calorimetry, Differential Scanning', 'Hot Temperature', 'Humans', 'In Vitro Techniques', 'Lipid Bilayers', 'Lipids', 'Skin', 'Skin Absorption', 'Sodium Dodecyl Sulfate', 'X-Ray Diffraction'] | 7,855,044 | [['E05.196.131.310', 'E05.196.370.310'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D10.570.510', 'J01.637.087.500.510'], ['D10'], ['A17.815'], ['G03.015.500.750'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Antimicrobial peptides (Temporin A and Iseganan IB-367): effect on the cysticerci of Taenia crassiceps. | Taenia solium infections continue being a health problem in undeveloped countries, and few effective control measures against this parasite are being applied. Antimicrobial peptides (AMPs) belong to the innate immune response and capable of destroying pathogens. We tested the ability of two AMPs, Temporin A (TA) and Is... | ['Animals', 'Anthelmintics', 'Antimicrobial Cationic Peptides', 'Cysticercosis', 'Cysticercus', 'Female', 'Mice', 'Microscopy', 'Microscopy, Electron', 'Peptides', 'Proteins', 'Taenia'] | 19,146,887 | [['B01.050'], ['D27.505.954.122.250.075'], ['D12.644.050', 'D12.776.543.695.054'], ['C01.610.335.190.902.185'], ['B01.050.500.500.736.215.895.286'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E01.370.350.515.402', 'E05.595.402'], ['D12.644'], ['D12.776'], ['B01.050... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
H19 suppresses the growth of hepatoblastoma cells by promoting their apoptosis via the signaling pathways of miR-675/FADD and miR-138/PTK2. | BACKGROUND: The objective of this study was to clarify the molecular pathways involved in hepatitis B virus (HBV)-induced hepatoblastoma.METHOD: The expression of factors in different signaling pathways (H19, miR-675, miR-138, protein tyrosine kinase 2 [PTK2], fas-associated death domain [FADD], hypoxia-inducible facto... | ['Apoptosis', 'Base Sequence', 'Carcinogenesis', 'Cell Line, Tumor', 'Cell Proliferation', 'Fas-Associated Death Domain Protein', 'Female', 'Focal Adhesion Kinase 1', 'Gene Expression Regulation, Neoplastic', 'Hepatitis B', 'Hepatitis B virus', 'Hepatoblastoma', 'Humans', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'I... | 30,367,502 | [['G04.146.954.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.697.098', 'C23.550.727.098'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.360.024.285.200', 'D12.644.360.024.500.124', 'D12.644.360.075.421.200', 'D12.776.157.057.018.200', 'D12.776.157.0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Biosynthesis of chlorophyll b. | Using [14C]chlorophyll a derived from a mutant of wheat lacking chlorophyll b, spinach thylakoids from very young leaves and cucumber thylakoids of irradiated, etiolated cotyledons convert chlorophyll a to b with apparent yields of 19% and 5%, respectively. | ['Chlorophyll', 'Chloroplasts', 'Darkness', 'Mutation', 'Plant Physiological Phenomena', 'Plants', 'Triticum'] | 912,600 | [['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['A11.284.430.214.190.875.700.140'], ['G01.590.540.233'], ['G05.365.590'], ['G15'], ['B01.650'], ['B01.650.940.800.575.912.250.822.918']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of rare anti-phospholipid/protein co-factor autoantibodies in patients with systemic lupus erythematosus. | Lupus anticoagulant (LA) and beta2-glikoprotein I (b2GPI) dependent anti-cardiolipin (aCL) are part of the diagnostic criteria both of systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS). Anti-phospholipid antibodies (aPL) may also bind to other phospholipids and/or protein co-factors. In the presen... | ['Adult', 'Annexin A5', 'Antibodies, Anticardiolipin', 'Antibodies, Antiphospholipid', 'Antiphospholipid Syndrome', 'Autoantibodies', 'Autoimmune Diseases', 'Female', 'Humans', 'Lupus Coagulation Inhibitor', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Phosphatidylserines', 'Prothrombin', 'Thrombosis'] | 19,626,489 | [['M01.060.116'], ['D12.776.157.125.050.100'], ['D12.776.124.486.485.114.323.210.100', 'D12.776.124.790.651.114.323.210.100', 'D12.776.377.715.548.114.323.210.100'], ['D12.776.124.486.485.114.323.210', 'D12.776.124.790.651.114.323.210', 'D12.776.377.715.548.114.323.210'], ['C20.111.197'], ['D12.776.124.486.485.114.323'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A microfluidic platform for pharmaceutical salt screening. | We describe a microfluidic platform comprised of 48 wells to screen for pharmaceutical salts. Solutions of pharmaceutical parent compounds (PCs) and salt formers (SFs) are mixed on-chip in a combinatorial fashion in arrays of 87.5-nanolitre wells, which constitutes a drastic reduction of the volume of PC solution neede... | ['Dimethylpolysiloxanes', 'Drug Evaluation, Preclinical', 'Ephedrine', 'Equipment Design', 'Microfluidic Analytical Techniques', 'Naproxen', 'Optical Phenomena', 'Pharmaceutical Preparations', 'Salts', 'Solvents', 'Spectrum Analysis, Raman'] | 21,956,673 | [['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['E05.290.750', 'E05.337.550'], ['D02.033.100.624.302', 'D02.033.755.624.302', 'D02.092.063.624.302', 'D02.092.471.683.430'], ['E05.320'], ['E05.588.465'], ['D02.455.426.559.847.638.472.500', 'D04.615.638.472.450'], [... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Association analysis of a functional catechol-o-methyltransferase gene polymorphism in schizophrenic patients in Taiwan. | The catechol-O-methyltransferase (COMT) gene was thought to be a candidate gene for schizophrenia because of its role in inactivating dopamine. This study examined the relationship between a functional polymorphism (val158met) of the COMT gene, schizophrenia and its associated behaviors. One hundred and ninety-eight Ch... | ['Adult', 'Asian Continental Ancestry Group', 'Catechol O-Methyltransferase', 'Cross-Cultural Comparison', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Schizophrenia', 'Taiwan'] | 11,150,892 | [['M01.060.116'], ['M01.686.508.200'], ['D08.811.913.555.500.250'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.795'], ['F03.700.750'], ['Z01.252.474.872', 'Z01.639.850']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Carboxydothermus siderophilus sp. nov., a thermophilic, hydrogenogenic, carboxydotrophic, dissimilatory Fe(III)-reducing bacterium from a Kamchatka hot spring. | A novel anaerobic, thermophilic, Fe(III)-reducing, CO-utilizing bacterium, strain 1315(T), was isolated from a hot spring of Geyser Valley on the Kamchatka Peninsula. Cells of the new isolate were Gram-positive, short rods. Growth was observed at 52-70 degrees C, with an optimum at 65 degrees C, and at pH 5.5-8.5, with... | ['Carbon Dioxide', 'Ferric Compounds', 'Gram-Positive Asporogenous Rods, Irregular', 'Hot Springs', 'Hot Temperature', 'Hydrogen', 'Molecular Sequence Data', 'Oxidation-Reduction', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Species Specificity'] | 19,196,756 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.490.100'], ['B03.510.460.400.400'], ['G01.311.355.750.500', 'G16.500.275.260.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D01.268.406', 'D01.362.340'], ['L01.453... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effect of chelating agents and respiratory inhibitors on regulation of the cadA gene in Escherichia coli. | The cadA gene that encodes lysine decarboxylase in Escherichia coli is induced by low pH and - during anaerobic growth - by the substrate, lysine. We used operon fusions of cadA to lacZ to investigate the effects of aeration on cadA regulation. When an insertion mutation in osmZ (= hns) was introduced, a cadA-lacZ fusi... | ['Aluminum Silicates', 'Carboxy-Lyases', 'Chelating Agents', 'Cyanides', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Mutation', 'Oxygen Consumption'] | 9,075,621 | [['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D08.811.520.224.125'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D01.248.497.158.291', 'D01.625.400.100'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.34... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Purification and thermal stability of several amino acid-specific tRNAs from an extreme thermophile, Thermus thermophilus HB8. | Three species of methionine tRNAs and phenylalanine, tyrosine, and isoleucine tRNAs were purified from an extreme thermophile, Thermus thermophilus HB8. Formylation studies of the three methionine tRNAs and their codon-specific binding activities to ribosomes showed that two of them (named tRNAf1Met and tRNAf2Met) were... | ['Codon', 'Drug Stability', 'Escherichia coli', 'Isoleucine', 'Kinetics', 'Nucleic Acid Denaturation', 'Phenylalanine', 'RNA, Transfer', 'RNA, Transfer, Amino Acyl', 'Ribonucleosides', 'Ribosomes', 'Species Specificity', 'Thermus', 'Tyrosine'] | 6,987,208 | [['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['E05.916.330'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.070.577', 'D12.125.142.383'], ['G01.374.661', 'G02.111.490'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['D12.125.072.050.685', 'D12.125.142.666'], ['D13.444.73... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acupuncture for patients with mild hypertension: study protocol of an open-label multicenter randomized controlled trial. | BACKGROUND: Several studies using acupuncture to treat essential hypertension have been carried out. However, whether acupuncture is efficacious for hypertension is still controversial. Therefore, this trial aims to evaluate the efficacy and safety of acupuncture for patients with mild hypertension.METHODS/DESIGN: This... | ['Acupuncture Points', 'Acupuncture Therapy', 'Adult', 'Aged', 'Blood Pressure', 'China', 'Clinical Protocols', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Research Design', 'Severity of Illness Index', 'Time Factors', 'Treatment Outcome'] | 24,216,113 | [['E02.190.044.555.035'], ['E02.190.044'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['Z01.252.474.164'], ['E02.183', 'N05.715.360.330.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E05.581.500', 'H01.770.644.728'], ['E05.318.308.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Metacognitive appraisal of memory inconsistency for traumatic events in Dutch veterans. | Although memories of traumatic events are often remembered vividly, these memories are subject to change over time. In our previous study, we found that Dutch infantry veterans who had served in Iraq often reported stressful events at a second assessment point that they had not reported during a prior assessment point ... | ['Adult', 'Female', 'Follow-Up Studies', 'Humans', 'Iraq War, 2003-2011', 'Judgment', 'Life Change Events', 'Male', 'Mental Recall', 'Metacognition', 'Netherlands', 'Repression, Psychology', 'Stress Disorders, Post-Traumatic', 'Veterans', 'Young Adult'] | 25,084,475 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.950.250.782', 'K01.400.504.984.249'], ['F02.463.785.626'], ['F01.829.458.410'], ['F02.463.425.540.641'], ['F02.463.188.756'], ['Z01.542.651'], ['F01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Geographic Variation Immediate and Delayed Breast Reconstruction Utilization in Ontario, Canada and Plastic Surgeon Availability: A Population-Based Observational Study. | BACKGROUND: Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis.METHODS: We linked administrative data from Ontario Canada to c... | ['Adolescent', 'Adult', 'Aged', 'Breast Neoplasms', 'Female', 'Health Services Accessibility', 'Humans', 'Mammaplasty', 'Mastectomy', 'Middle Aged', 'Ontario', 'Surgeons', 'Young Adult'] | 25,896,900 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['E04.466'], ['M01.060.116.630'], ['Z01.107.567.176.639'], ['M01.526.485.810.910', 'N02.360.810.910'], ['M01.06... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of ZASC1 encoding a Kr?ppel-like zinc finger protein as a novel target for 3q26 amplification in esophageal squamous cell carcinomas. | Among the transcription factors that direct proliferation, differentiation, and death of cells, several Kr?ppel-like zinc finger molecules such as GLI1 and ZNF147 can become oncogenic when the genes encoding them are overexpressed by the DNA amplification mechanism. Here, we report the discovery of a novel member of th... | ['Aged', 'Aged, 80 and over', 'Amino Acid Sequence', 'Carcinoma, Squamous Cell', 'Carrier Proteins', 'Cell Division', 'Chromosomes, Human, Pair 3', 'DNA-Binding Proteins', 'Esophageal Neoplasms', 'Female', 'Gene Amplification', 'Humans', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Nuclear Proteins', 'Reverse Tra... | 14,522,885 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.157'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250'], ['D12.776.260'], ['C04.588... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Centralized Data Management in a Multicountry, Multisite Population-based Study. | BACKGROUND: A centralized data management system was developed for data collection and processing for the Aetiology of Neonatal Infection in South Asia (ANISA) study. ANISA is a longitudinal cohort study involving neonatal infection surveillance and etiology detection in multiple sites in South Asia. The primary goal o... | ['Asia, Western', 'Communicable Diseases', 'Community-Acquired Infections', 'Data Collection', 'Epidemiological Monitoring', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male'] | 27,070,059 | [['Z01.252.245'], ['C01.221', 'C23.550.291.531'], ['C01.234'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E05.318.375', 'N06.850.520.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C16.614']] | ['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation. | BACKGROUND: p300 (KAT3B) lysine acetyltransferase activity is modulated under different physiological and pathological contexts through the induction of trans-autoacetylation. This phenomenon is mediated by several factors, mechanisms of which are not fully understood.METHODS: Through acetyltransferase assays using ful... | ['Acetylation', 'E1A-Associated p300 Protein', 'Histones', 'Humans', 'Nuclear Proteins', 'Protein Binding', 'Protein Conformation', 'Protein Folding', 'Protein Multimerization', 'Tongue Neoplasms', 'Tumor Cells, Cultured'] | 29,746,960 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D08.811.913.050.134.415.500.575.600', 'D12.776.930.680.600'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['G01.154.651'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of microbial protein, obtained on a hydrocarbon base (fermosin), with a defined fatty acid composition on fat metabolism and fat composition in slaughter animals. 1. The effect of fermosin on the composition of broiler depot fat]. | A study has been undertaken to investigate the influence of fermosin on the depot-fat composition of broilers and the oxidative stability of these fats in parallel with test animals fed yeast conventional produced on carbohydrate base. The data obtained are discussed with reference to literature. | ['Adipose Tissue', 'Animals', 'Body Composition', 'Chickens', 'Fats', 'Fatty Acids', 'Oxidation-Reduction', 'Yeast, Dried'] | 3,231,251 | [['A10.165.114'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D10.212'], ['D10.251'], ['G02.700', 'G03.295.531'], ['G07.203.300.456.933', 'J02.500.456.933']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
NMR and mutagenesis of human copper transporter 1 (hCtr1) show that Cys-189 is required for correct folding and dimerization. | The human high-affinity copper transporter (hCtr1) is a membrane protein that is predicted to have three transmembrane helices and two methionine-rich metal binding motifs. As an oligomeric polytopic membrane protein, hCtr1 is a challenging system for experimental structure determination. The results of an initial appl... | ['Cation Transport Proteins', 'Cloning, Molecular', 'Copper Transporter 1', 'Cysteine', 'Dimerization', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Magnetic Resonance Spectroscopy', 'Models, Biological', 'Models, Genetic', 'Protein Folding'] | 17,959,139 | [['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['E05.393.220'], ['D12.776.157.530.450.250.578.875.500', 'D12.776.157.530.937.640.500', 'D12.776.543.585.450.250.578.875.500', 'D12.776.543.585.937.762.500'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G02.206', 'G03.230'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of fitness components in strains of Drosophila mulleri carrying different genotypes for an esterase. | Several fitness components in strains of Drosophila mulleri carrying the slow or the fast alleles for the major beta esterase (esterase-4) found in this species, as well as in heterozygous flies in which the slow or fast alleles came from one of the parents, were evaluated. Twelve components were analysed including lon... | ['Adaptation, Biological', 'Animals', 'Drosophila', 'Esterases', 'Female', 'Genotype', 'Longevity', 'Male', 'Sexual Behavior, Animal'] | 11,503,973 | [['G16.012'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D08.811.277.352'], ['G05.380'], ['G07.345.124.519', 'G07.540'], ['F01.145.113.252.748']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. | While the transmembrane protein Notch plays an important role in various aspects of development, and diseases including tumors and neurological disorders, the intracellular pathway of mammalian Notch remains very elusive. To understand the intracellular pathway of mammalian Notch, the role of the bHLH genes Hes1 and He... | ['Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Cell Differentiation', 'Cells, Cultured', 'Gene Expression Regulation', 'Homeodomain Proteins', 'Immunohistochemistry', 'Membrane Proteins', 'Mice', 'Muscle Proteins', 'Neurons', 'Receptors, Notch', 'Retroviridae', 'Transcription Factor HES-1'] | 10,205,173 | [['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['G04.152'], ['A11.251'], ['G05.308'], ['D12.776.260.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The in vitro cytotoxicity of urine from patients with interstitial cystitis. | Urine from patients with interstitial cystitis has been reported to be more cytotoxic than urine from healthy subjects when tested in vitro against cells from a normal urothelial cell line. The purpose of the present study was to develop a method to measure urinary cytotoxicity and so make it possible to estimate the t... | ['Adult', 'Cystitis', 'Female', 'Humans', 'Middle Aged', 'Tumor Cells, Cultured', 'Urine'] | 8,254,814 | [['M01.060.116'], ['C12.777.829.495', 'C13.351.968.829.495'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A11.251.860'], ['A12.207.927']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The acquisition of self-stimulation of the medical prefrontal cortex following exposure to escapable or inescapable footshock. | The effect of acute stress on the acquisition of an instrumental action reinforced by electrical stimulation of the medial prefrontal cortex (MPC) was investigated by exposing rats to either escapable, inescapable or no footshock prior to daily self-stimulation training sessions. Treatment with inescapable footshock di... | ['Animals', 'Arousal', 'Brain Mapping', 'Electroshock', 'Escape Reaction', 'Fear', 'Frontal Lobe', 'Male', 'Mental Recall', 'Motivation', 'Motor Activity', 'Rats', 'Rats, Inbred Strains', 'Self Stimulation'] | 1,867,758 | [['B01.050'], ['F02.830.104', 'G11.561.035'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E05.723.402.403', 'F04.669.224'], ['F01.145.113.780.688', 'F01.145.367', 'F01.145.875.439.500.688', 'G07.568.500.590.688', 'G11.427.410.568.850.688'], ['F01.470.361'], ['A08.186.211.200.885.287.500... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-quantal acetylcholine release is increased after nitric oxide synthase inhibition. | After anticholinesterase treatment, depolarization of the postsynaptic muscle membrane by about 5 mV develops due to non-quantally released acetylcholine from the motor nerve terminal and can be revealed as hyperpolarization by the addition of curare (H-effect). The H-effect increases significantly to 8.7 mV after inhi... | ['Acetylcholine', 'Animals', 'Cholinesterase Inhibitors', 'Diaphragm', 'Enzyme Inhibitors', 'Female', 'Membrane Potentials', 'NG-Nitroarginine Methyl Ester', 'Nerve Endings', 'Neuromuscular Junction', 'Neuromuscular Nondepolarizing Agents', 'Nitric Oxide Synthase', 'Rats', 'Rats, Wistar', 'Receptors, Neurotransmitter',... | 10,638,684 | [['D02.092.211.111'], ['B01.050'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['A02.633.567.900.300'], ['D27.505.519.389'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['A08.800.550'], ['A08.800.550.550.550', 'A08.850.550.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective staining of platelet glycoproteins using two-dimensional O'Farrell gel electrophoresis and avidin-biotin-conjugated lectins. | A time-saving and sensitive high resolution method for the analysis and identification of platelet glycoproteins using nonradioactive compounds has been developed. Platelet proteins (50 micrograms) of normal subjects were separated by isoelectric focusing and SDS-PAGE. Proteins were either stained with silver or electr... | ['Avidin', 'Biotin', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Isoelectric Focusing', 'Lectins', 'Peroxidases', 'Platelet Membrane Glycoproteins', 'Staining and Labeling'] | 2,451,305 | [['D12.776.034.614.300', 'D12.776.256.159.157.663.300', 'D12.776.290.663.100', 'D12.776.395.175'], ['D03.383.129.308.080', 'D08.211.096'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.401.663', 'E05.301.300.663'], ['D12.776.503'], ['D08.811.682.732'], ['D12.776.395.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Uric Acid Levels Correlate with Sensory Nerve Function in Healthy Subjects. | BACKGROUND: High levels of uric acid (UA) are associated with various peripheral neuropathies. Furthermore, uric acid levels have been found to correlate with both the clinical and electrophysiological severity of diabetic sensorimotor polyneuropathy, mainly with sensory functions.OBJECTIVES: To determine whether highe... | ['Adult', 'Aged', 'Female', 'Healthy Volunteers', 'Humans', 'Male', 'Middle Aged', 'Peripheral Nerves', 'Sensation', 'Sensory Thresholds', 'Uric Acid'] | 30,880,660 | [['M01.060.116'], ['M01.060.116.100'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.800.800'], ['F02.830.816', 'G11.561.790'], ['F02.463.593.710'], ['D03.132.960.877', 'D03.633.100.759.758.824.877']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Circulating adiponectin levels are associated with peak oxygen uptake in Japanese. | OBJECTIVE: The aim of this study was to investigate the link between circulating adiponectin levels and peak oxygen uptake and/or physical activity in Japanese.METHODS: A total of 528 subjects (188 men and 340 women) were enrolled in this cross-sectional study. Circulating adiponectin levels, physical activity measured... | ['Accelerometry', 'Adiponectin', 'Adult', 'Blood Chemical Analysis', 'Blood Pressure', 'Body Composition', 'Cross-Sectional Studies', 'Energy Intake', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Motor Activity', 'Oxygen', 'Peak Expiratory Flow Rate'] | 24,706,325 | [['E05.003'], ['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E05.318.372.500.875', 'N05.715.360.330.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Transfer of PBDEs and chlorinated POPs from mother to pup during lactation in harp seals Phoca groenlandica. | Seven mother-pup pairs of harp seal (Phoca groenlandica) were sampled during the lactation season near Magdalen Islands, QC, Canada. The blubber and serum of pups and mothers as well as the milk of mothers were analyzed for polybrominated diphenyl ethers and several chlorinated persistent organic pollutants (POPs) to e... | ['Adipose Tissue', 'Animals', 'Animals, Suckling', 'Biopsy', 'Environmental Pollutants', 'Female', 'Halogenated Diphenyl Ethers', 'Hydrocarbons, Chlorinated', 'Lactation', 'Milk', 'Principal Component Analysis', 'Quebec', 'Seals, Earless', 'Time Factors'] | 22,239,965 | [['A10.165.114'], ['B01.050'], ['B01.050.050.293'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D27.888.284'], ['D02.355.726.601', 'D02.455.426.559.389.657.654.601'], ['D02.455.526.439'], ['G08.686.523', 'G08.686.702.50... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Hamster embryo cells transformed by herpes simplex virus: reactions with adeno-associated satellite virus (AAV) and its adenovirus helpers. | We have studied the reactions of hamster embryo cells transformed by ultraviolet-inactivated herpes simplex type 2 (333-8-9 T cells) to infections with adeno-associated satellite virus (AAV) and its adenovirus helpers. Resident HSV structural antigens were not detectable in early or late passage of 333-8-9 T cells. AAV... | ['Adenoviridae', 'Adenoviruses, Human', 'Adenoviruses, Simian', 'Animals', 'Antigens, Viral', 'Cell Transformation, Neoplastic', 'Cricetinae', 'Dependovirus', 'Genes, Viral', 'Helper Viruses', 'Inclusion Bodies, Viral', 'Microscopy, Electron', 'Simplexvirus'] | 210,924 | [['B04.280.030'], ['B04.280.030.500.350'], ['B04.280.030.500.700'], ['B01.050'], ['D23.050.327'], ['C04.697.098.500', 'C23.550.727.098.500'], ['B01.050.150.900.649.313.992.635.075.250'], ['B04.280.580.650.170'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['B04.423'], ['A11.28... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro clonal analysis of rat cerebral cortical neurons expressing latexin, a subtype-specific molecular marker of glutamatergic neurons. | Latexin is expressed in a subset of glutamatergic projection neurons located in the lateral but not the dorsomedial neocortex in rat. In the present study, we performed clonal analysis of embryonic cortical neurons in vitro using latexin as a subtype-specific molecular marker of glutamatergic neurons to address whether... | ['Animals', 'Antigens', 'Biomarkers', 'Cell Lineage', 'Cerebral Cortex', 'Clone Cells', 'Female', 'Glutamic Acid', 'In Vitro Techniques', 'Neurons', 'Pregnancy', 'Rats', 'Rats, Wistar', 'Stem Cells'] | 11,744,110 | [['B01.050'], ['D23.050'], ['D23.101'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A08.186.211.200.885.287.500'], ['A11.251.353'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['E05.481'], ['A08.675', 'A11.671'], ['G08.686.784.769'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pollen-pistil interactions and the endomembrane system. | The endomembrane system offers many potential points where plant mating can be effectively controlled. This results from two basic features of angiosperm reproduction: the requirement for pollen tubes to pass through sporophytic tissues to gain access to ovules and the physiology of pollen tube growth that provides it ... | ['Cell Membrane', 'Inbreeding', 'Ovule', 'Pollen', 'Pollen Tube', 'Species Specificity', 'Tobacco'] | 20,363,870 | [['A11.284.149'], ['E05.820.150.520', 'G05.090.403'], ['A18.024.249.500.249.249'], ['A18.024.249.500.249.500'], ['A18.024.249.500.249.500.500'], ['G16.824'], ['B01.650.940.800.575.912.250.908.500.900']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence, trends and severity of primary postpartum haemorrhage in Australia: A population-based study using Victorian Perinatal Data Collection data for 764 244 births. | BACKGROUND: Increasing incidence and severity of postpartum haemorrhage, together with postpartum haemorrhage-associated morbidities, have been reported in many high-resource countries. In-depth analysis of such factors in Victorian births since 2002 was lacking.AIMS: Our aim was to determine the incidence and trends f... | ['Cross-Sectional Studies', 'Delivery, Obstetric', 'Female', 'Humans', 'Hysterectomy', 'Incidence', 'Postpartum Hemorrhage', 'Risk Factors', 'Victoria'] | 29,787,638 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C13.703.420.725', 'C13.703.844.700', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Transcriptional profiling on all open reading frames of Saccharomyces cerevisiae. | Open reading frames (6116) of the budding yeast Saccharomyces cerevisiae were PCR-amplified from genomic DNA using 12,232 primers specific to the ends of the coding sequences; the success rate of amplification was 97%. PCR-products were made accessible to hybridization by being arrayed at very high density on solid sup... | ['Blotting, Western', 'DNA Primers', 'DNA Probes', 'Electrophoresis, Agar Gel', 'Electrophoresis, Polyacrylamide Gel', 'Enzymes', 'Gene Expression Regulation, Fungal', 'Image Processing, Computer-Assisted', 'Nucleic Acid Hybridization', 'Open Reading Frames', 'Phenol', 'Polymerase Chain Reaction', 'RNA, Fungal', 'Robot... | 9,791,892 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.196.401.402', 'E05.301.300.319'], ['D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Effect of ethanol extract of HPRS, a Traditional Chinese Medicine formula, on HCT116 cell Line. | OBJECTIVE: In this study, we investigated the effects of ethanol extract of Hupiruisu Fang (HPRS), a
formula of Traditional Chinese Medicine, on HCT116 cell line.METHODS: MKN45, A549, Hela and HCT116 cells were treated with ethanol extract of HPRS alone or
the extract plus 5-Fluorouracil (5-FU) for 48 h, and then the c... | ['Antineoplastic Agents', 'Apoptosis', 'Caspase 3', 'Cell Survival', 'Colonic Neoplasms', 'Drugs, Chinese Herbal', 'HCT116 Cells', 'Humans', 'Proto-Oncogene Proteins c-bcl-2'] | 29,949,709 | [['D27.505.954.248'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G04.346'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sheep have an unusual variant of the brain-specific metallothionein, metallothionein-III. | Sheep metallothionein-III (MT-III) cDNA was isolated from a brain cDNA library and characterized. In contrast with MT-III from other species, sheep MT-III cDNA is predicted to encode a protein with significantly different metal-binding properties, owing to the loss of three of its cysteine residues. RT-PCR from other s... | ['Amino Acid Sequence', 'Animals', 'Brain', 'Cells, Cultured', 'DNA, Complementary', 'Gene Expression', 'Genetic Variation', 'Humans', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'RNA, Messenger', 'Rats', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Sheep', 'Tissue Distribution'] | 11,931,634 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A08.186.211'], ['A11.251'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.297'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.776.631'], ['D13.444.735.544'], ['B01.050.150.900.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Changes in total sperm count after gastric bypass and sleeve gastrectomy: the BARIASPERM prospective study. | BACKGROUND: The massive weight loss induced by bariatric surgery is associated with major benefits, but the effect on semen variables is still uncertain.OBJECTIVES: To explore semen modifications with gastric bypass and sleeve gastrectomy.SETTING: Five French University Hospitals.METHODS: Male candidates for bariatric ... | ['Adult', 'Gastrectomy', 'Gastric Bypass', 'Humans', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Oligospermia', 'Postoperative Complications', 'Prospective Studies', 'Sperm Count', 'Spermatozoa'] | 31,147,284 | [['M01.060.116'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500.700', 'C23.888.144.699.500.500', 'E01.370.600.115.100.160.120.699.500.500', 'G07.100.100.160.120.699.500.500'], ['C12.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure determination and biosynthesis of a novel metabolite of Fusarium culmorum, apotrichodiol. | A novel dead-end metabolite of Fusarium culmorum was isolated and characterized (Zamir, L. O., and Devor, K. A. (1987) J. Biol. Chem. 15348-15353). This 3 alpha, 13-dihydroxy-apotrichothec-9-ene is herein given the trivial name of apotrichodiol to indicate its basic structure. The characterization of apotrichodiol was ... | ['Chromatography, High Pressure Liquid', 'Fusarium', 'Magnetic Resonance Spectroscopy', 'Mevalonic Acid', 'Sesquiterpenes', 'Trichothecenes'] | 3,680,200 | [['E05.196.181.400.300'], ['B01.300.381.366'], ['E05.196.867.519'], ['D02.241.511.579'], ['D02.455.849.765'], ['D02.455.849.765.850', 'D04.345.891', 'D23.946.587.933']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel Histone Deacetylase Inhibitor Modulates Cardiac Peroxisome Proliferator-Activated Receptors and Inflammatory Cytokines in Heart Failure. | BACKGROUND: Heart failure (HF) affects cardiac metabolism and inflammation. Histone deacetylases (HDACs) play a critical role in cardiac pathophysiology. This study investigated whether HDAC inhibition can regulate HF by modifying cardiac inflammation and peroxisome proliferator-activated receptor (PPAR) isoforms.METHO... | ['Adrenergic beta-Agonists', 'Animals', 'Cells, Cultured', 'Cytokines', 'Heart Failure', 'Heart Ventricles', 'Histone Deacetylase Inhibitors', 'Histone Deacetylases', 'Hydroxamic Acids', 'Indoles', 'Isoenzymes', 'Isoproterenol', 'Male', 'Mice', 'Myocarditis', 'Myocardium', 'Peroxisome Proliferator-Activated Receptors',... | 26,304,494 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['B01.050'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C14.280.434'], ['A07.541.560'], ['D27.505.519.389.360'], ['D08.811.277.087.520'], ['D02.092.570.394', 'D02.241.511.372'], ['D03.633.100.473'], ['D08.811.348', 'D12.776.800.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of initial gefitinib or erlotinib versus chemotherapy on central nervous system progression in advanced non-small cell lung cancer with EGFR mutations. | PURPOSE: This retrospective study was undertaken to investigate the impact of initial gefitinib or erlotinib (EGFR tyrosine kinase inhibitor, EGFR-TKI) versus chemotherapy on the risk of central nervous system (CNS) progression in advanced non-small cell lung cancer (NSCLC) with EGFR mutations.EXPERIMENTAL DESIGN: Pati... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Carcinoma, Non-Small-Cell Lung', 'Central Nervous System Neoplasms', 'Disease Progression', 'ErbB Receptors', 'Erlotinib Hydrochloride', 'Female', 'Gefitinib', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Mutation', 'Neoplasm Staging', 'Protein Kin... | 22,733,536 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C04.588.614.250', 'C10.551.240'], ['C23.550.291.656'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High- versus low-top shoes for the prevention of ankle sprains in basketball players. A prospective randomized study. | Using a prospective, randomized experimental design, 622 college intramural basketball players were stratified by a previous history of ankle sprains to wear a new pair of either high-top, high-top with inflatable air chambers, or low-top basketball shoes during all games for a complete season. Subjects were asked to c... | ['Adult', 'Ankle Injuries', 'Athletic Injuries', 'Basketball', 'Female', 'Humans', 'Male', 'Prospective Studies', 'Random Allocation', 'Research Design', 'Shoes', 'Sprains and Strains'] | 8,368,420 | [['M01.060.116'], ['C26.558.100'], ['C26.115'], ['I03.450.642.845.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E05.581.500', 'H01.... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
Lack of local anaesthetic efficacy of fentanyl in the abaxial sesamoid block model. | Fentanyl and other opioid drugs have their effect in the central nervous system; however, activity at peripheral sites has also been demonstrated. Pain-suppression activity at peripheral sites raises the possibility of skilled individuals producing local anaesthetic effects with small doses of opioid drugs that would b... | ['Analgesics, Opioid', 'Anesthetics, Local', 'Animals', 'Female', 'Fentanyl', 'Forelimb', 'Horses', 'Injections, Subcutaneous', 'Nerve Block', 'Time Factors'] | 10,211,717 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['D03.383.621.265'], ['A13.395'], ['B01.050.150.900.649.313.984.235.472'], ['E02.319.267.530.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Syphilis consequences and implications in delayed diagnosis: five cases of secondary syphilis presenting with ocular symptoms. | Ocular manifestations of syphilis are uncommon. Five cases of ocular syphilis are presented, in four of which there was a delay in diagnosis. Four of the patients were men who have sex with men (MSM), and four patients were HIV negative. | ['Adult', 'Delayed Diagnosis', 'Eye Infections, Bacterial', 'HIV Seronegativity', 'Homosexuality, Male', 'Humans', 'Male', 'Medical History Taking', 'Middle Aged', 'Syphilis'] | 21,059,839 | [['M01.060.116'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['C01.150.252.289', 'C01.375.354', 'C11.294.354'], ['G12.400'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.510'], ['M01.060.116.630'], ['C01.150.252.400.794.840.500', 'C01.150.252.400.840... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of a crunchy pseudo-chewing sound on perceived texture of softened foods. | Elderly individuals whose ability to chew and swallow has declined are often restricted to unpleasant diets of very soft food, leading to a poor appetite. To address this problem, we aimed to investigate the influence of altered auditory input of chewing sounds on the perception of food texture. The modified chewing so... | ['Adult', 'Analysis of Variance', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Fourier Analysis', 'Humans', 'Male', 'Masseter Muscle', 'Mastication', 'Middle Aged', 'Sound', 'Surface Properties', 'Surveys and Questionnaires', 'Touch Perception', 'Young Adult'] | 27,720,736 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.600.500', 'A14.530.630'], ['G07.203.650.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Isolation and characterization of the beta-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12. | beta-Ketoacyl-acyl carrier protein (ACP) synthase III catalyzes the condensation of acetyl-CoA with malonyl-ACP in dissociated (Type II) fatty acid synthase systems. A synthase III mutant was used to localize the structural gene to the 24.5-min region of the Escherichia coli chromosome, and the defective synthase III a... | ['3-Oxoacyl-(Acyl-Carrier-Protein) Synthase', 'Amino Acid Sequence', 'Base Sequence', 'Chromosomes, Bacterial', 'Cloning, Molecular', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Fatty Acids', 'Isoelectric Point', 'Molecular Sequence Data', 'Mutation', 'Open Reading Frames', 'Plasmids', 'Restriction Mapp... | 1,551,888 | [['D08.811.913.050.622'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['E05.393.220'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D10.251'], ['E05.301.300.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Symbolic play in children with autism spectrum disorder. | The relationship between symbolic play and other domains, such as degree of autistic symptomatology, nonverbal cognitive ability, receptive language, expressive language, and social development, was investigated. The assessment files of 101 children with Autism Spectrum Disorder were studied. Nonverbal cognitive abilit... | ['Autistic Disorder', 'Child', 'Child, Preschool', 'Cognition Disorders', 'Female', 'Humans', 'Language Tests', 'Male', 'Nonverbal Communication', 'Play and Playthings', 'Social Behavior', 'Socialization', 'Surveys and Questionnaires', 'Symbolism', 'Verbal Behavior', 'Wechsler Scales'] | 17,082,977 | [['F03.625.164.113.500'], ['M01.060.406'], ['M01.060.406.448'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['F01.145.209.530', 'L01.143.649'], ['I03.450.642.693'], ['F01.145.813'], ['I01.880.853.934'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['K01.4... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Outcome of redo surgical aortic valve replacement in patients 80 years and older: results from the Multicenter RECORD Initiative. | BACKGROUND: Octogenarians undergoing surgical aortic valve replacement (AVR) after prior cardiac surgery are expected to be at high risk of adverse events. This finding has recently popularized transcatheter AVR in this cohort.METHODS: This multicenter study includes 744 patients (99 were 80 years or older) who underwe... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Aortic Valve', 'Cardiac Surgical Procedures', 'Female', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Middle Aged', 'Reoperation', 'Retrospective Studies', 'Treatment Outcome'] | 24,036,070 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.541.510.110'], ['E04.100.376', 'E04.928.220'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.690'], ['E05.318.372.500.500.500', 'E05.318.372.5... | ['Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Academic Leadership Development: A Case Study. | A dean at a private school of nursing implemented a leadership development program for early- to mid-career nursing faculty consisting of one 4-hour evening session per academic quarter for 7 quarters. Eight faculty members who had expressed interest in assuming a leadership role or been recommended by their supervisor... | ['Faculty, Nursing', 'Humans', 'Leadership', 'Nursing Staff', 'Schools, Nursing', 'Students, Nursing'] | 26,194,960 | [['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['M01.526.485.680', 'N02.360.680'], ['I02.783.495.623'], ['M01.848.769.685']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of levobupivacaine and bupivacaine on rat myometrium. | OBJECTIVE: To study the effect of levobupivacaine and bupivacaine on the contractility of isolated uterine muscle strips from pregnant and non-pregnant female rats.METHODS: Full-thick myometrial strips were prepared from 18- to 21-day pregnant (n=8) and non-pregnant rats (n=7). After contractions became regular, strips... | ['Anesthetics, Local', 'Animals', 'Bupivacaine', 'Dose-Response Relationship, Drug', 'Female', 'In Vitro Techniques', 'Levobupivacaine', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Uterine Contraction'] | 16,909,479 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['D02.065.199.239', 'D02.092.146.113.239'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.481'], ['D02.065.199.239.500', 'D02.092.146.113.239.500'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delayed contrast agent kinetics in ischemic skeletal muscle. | PURPOSE: To detect skeletal muscle ischemia with first-pass gadolinium (Gd) kinetics after exercise.MATERIALS AND METHODS: Eleven subjects with intermittent claudication performed a symptom-limited bilateral plantar flexion exercise in the magnet. Regional ROIs were placed bilaterally in the gastrocnemius and soleus mu... | ['Age Factors', 'Aged', 'Analysis of Variance', 'Cohort Studies', 'Contrast Media', 'Exercise Test', 'Female', 'Gadolinium', 'Humans', 'Intermittent Claudication', 'Ischemia', 'Leg', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Probability', 'Risk Factors', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Se... | 16,374,885 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['D01.268.558... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The oldest patient to undergo aortic valve replacement. | As the American population ages, more elderly patients will present with significant heart disease. This group has an increase in morbidity and mortality with heart surgery as compared to a younger population. Severe aortic stenosis has a grave prognosis, and therefore surgical options should be considered even in the ... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Aortic Valve', 'Aortic Valve Stenosis', 'Follow-Up Studies', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Treatment Outcome'] | 10,844,391 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.... | ['Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conversion of food waste into hydrogen by thermophilic acidogenesis. | Conversion of food waste into hydrogen by thermophilic acidogenesis was investigated as a function of organic loading rate (OLR), hydraulic retention time (HRT) and pH in a continuous stirred tank reactor. In order to identify hydrogen-producing microorganisms, denaturing gradient gel electrophoresis (DGGE) of the poly... | ['Acids', 'Biodegradation, Environmental', 'Food', 'Hydrogen', 'Thermoanaerobacterium'] | 15,727,153 | [['D01.029'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G07.203.300', 'J02.500'], ['D01.268.406', 'D01.362.340'], ['B03.353.968', 'B03.510.460.400.400.800']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Calcitonin is a physiological inhibitor of prolactin secretion in ovariectomized female rats. | Calcitonin (CT) inhibits secretion of PRL when administered intravenously in rats and humans. It also inhibits PRL release from cultured rat anterior pituitary (AP) cells. Recent evidence suggests that CT-like immunoreactive peptide is synthesized and released from the AP gland. However, its physiological role in the r... | ['Animals', 'Animals, Newborn', 'Calcitonin', 'Cyclic AMP', 'Dopamine', 'Female', 'Immunization, Passive', 'Kidney', 'Ovariectomy', 'Pituitary Gland, Anterior', 'Prolactin', 'Rats'] | 8,612,519 | [['B01.050'], ['B01.050.050.282'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nephrotic syndrome associated with agnogenic myeloid metaplasia. | Extramedullary hematopoiesis being an important feature of agnogenic myeloid metaplasia (AMM), a chronic myeloproliferative disease of clonal origin, may affect the kidneys, but this condition is usually asymptomatic. Until now, there is only one reported case of nephrotic syndrome associated with AMM. We present a pat... | ['Glomerulonephritis, Membranous', 'Hematopoiesis, Extramedullary', 'Humans', 'Kidney', 'Male', 'Middle Aged', 'Nephrotic Syndrome', 'Primary Myelofibrosis'] | 12,002,777 | [['C12.777.419.570.363.625', 'C13.351.968.419.570.363.625', 'C20.111.535'], ['G04.152.825.463', 'G09.188.343.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['M01.060.116.630'], ['C12.777.419.630.643', 'C13.351.968.419.630.643'], ['C15.378.190.636.765']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association of Parkinson disease with structural and regulatory variants in the HLA region. | Historically, association of disease with the major histocompatibility complex (HLA) genes has been tested with HLA alleles that encode antigen-binding affinity. The association with Parkinson disease (PD), however, was discovered with noncoding SNPs in a genome-wide association study (GWAS). We show here that several ... | ['Aged', 'Alleles', 'Case-Control Studies', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genome-Wide Association Study', 'HLA-B Antigens', 'HLA-DQ alpha-Chains', 'HLA-DQ beta-Chains', 'HLA-DRB1 Chains', 'HLA-DRB4 Chains', 'HLA-DRB5 Chains', 'Haplotypes', 'Humans', 'Major Histocompatibility Complex', 'Meta-An... | 24,183,452 | [['M01.060.116.100'], ['G05.360.340.024.340.030'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of intellectual handicap in Western Australia: a community study. | OBJECTIVE: To produce comprehensive community based data on individuals with intellectual handicap, the level of retardation, associated handicaps and demographic data.DESIGN: Multiple sources of ascertainment were used to identify all children in birth cohorts, 1967-1976 inclusive, who had an IQ less than 70.SETTING: ... | ['Adolescent', 'Cerebral Palsy', 'Child', 'Congenital Abnormalities', 'Epilepsy', 'Female', 'Hearing Disorders', 'Humans', 'Intellectual Disability', 'Intelligence', 'Male', 'Prevalence', 'Vision Disorders', 'Western Australia'] | 1,736,085 | [['M01.060.057'], ['C10.228.140.140.254'], ['M01.060.406'], ['C16.131'], ['C10.228.140.490'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F01.752.543'], ['E05.318.308.985.525.750',... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Abnormalities of Gq-mediated cell signaling in Bartter and Gitelman syndromes. | BACKGROUND: The constitutive endothelial isoform of nitric oxide synthase (ecNOS) and nitric oxide (NO) production are increased in patients with Bartter syndrome (BS) and Gitelman (GS) syndrome and may reduce vascular tone. Moreover, these patients present an abnormal cell signaling [reduced stimulated intracellular c... | ['Adult', 'Bartter Syndrome', 'Calcium', 'Enzyme Activation', 'Female', 'GTP-Binding Protein alpha Subunits, Gq-G11', 'Heterotrimeric GTP-Binding Proteins', 'Humans', 'Inositol Phosphates', 'Isoenzymes', 'Male', 'Middle Aged', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type III', 'Protein Kinase C', 'Signal Transd... | 11,532,083 | [['M01.060.116'], ['C12.777.419.815.279', 'C13.351.968.419.815.279', 'C19.053.800.604.249'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.263', 'G03.328'], ['D08.811.277.040.330.300.200.100.300', 'D12.644.360.360.100.300', 'D12.776.157.325.332.100.300', 'D12.776.476.375.100.300', 'D12.776.543.325.10... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neutral trehalases catalyse intracellular trehalose breakdown in the filamentous fungi Aspergillus nidulans and Neurospora crassa. | A cAMP-activatable Ca2+-dependent neutral trehalase was identified in germinating conidia of Aspergillus nidulans and Neurospora crassa. Using a PCR approach, A. nidulans and N. crassa genes encoding homologues of the neutral trehalases found in several yeasts were cloned and sequenced. Disruption of the AntreB gene en... | ['Amino Acid Sequence', 'Aspergillus nidulans', 'Calcium', 'Carbon', 'Cyclic AMP', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Genetic Engineering', 'Heat-Shock Response', 'Molecular Sequence Data', 'Mutation', 'Neurospora crassa', 'Sequence Homology, Amino Acid', 'Spores, Fungal', 'Trehalase', 'Trehalose... | 10,320,571 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.300.381.081.420'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.150'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.776.354'], ['G05.308.330'], ['E05.393.420'], ['G07.775.500'], ['L01.453.24... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chronic Hepatitis C Treatment with Direct-Acting Antiviral Agents in a Real-Life Setting. | BACKGROUND: In clinical trials, new oral direct-acting antiviral agent therapies have demonstrated a high sustained virological response rate in patients with hepatitis C virus infection. We aimed to analyze the efficacy and safety data from direct-acting antiviral agent interferon-free therapy in hepatitis C virus inf... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antiviral Agents', 'Carcinoma, Hepatocellular', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Liver Cirrhosis', 'Liver Neoplasms', 'Male', 'Mexico', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Transfusion Reaction'] | 27,623,039 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.388'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Age- and breed-dependent adapted immune responsiveness of poultry to intratracheal-administered, pathogen-associated molecular patterns. | Immune modulation of poultry by airborne pathogen-associated molecular patterns (PAMP) was studied. White and Brown layer chicks were exposed intratracheally during 5 consecutive days at 7 wk of age with Escherichia coli-derived lipopolysaccharide (LPS), Saccharomyces cerevisiae-derived 1,3 beta-glucan (BGL), a combina... | ['Aging', 'Animals', 'Antibodies', 'Chickens', 'Female', 'Humans', 'Injections, Spinal', 'Rabbits', 'Serum Albumin', 'Time Factors', 'Weight Gain', 'gamma-Globulins'] | 17,135,672 | [['G07.345.124'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.580'], ['B01.050.150.900.649.313.968.700'], ['D12.776.034.841', 'D12.776.12... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments. | Alzheimer's disease (AD) is multifactorial with unclear etiopathology. Due to the complexity of AD, many attempted single therapy treatments, like Aâ immunization, have generally failed. Therefore, there is a need for drugs with multiple benefits. Naturally occurring phytochemicals with neuroprotective, anti-amyloidoge... | ['Alzheimer Disease', 'Amyloid Precursor Protein Secretases', 'Amyloid beta-Peptides', 'Amyloid beta-Protein Precursor', 'Animals', 'Aspartic Acid Endopeptidases', 'Brain', 'Cognition Disorders', 'Disease Models, Animal', 'Homocysteine', 'Male', 'Maze Learning', 'Moringa oleifera', 'Nerve Tissue Proteins', 'Neurons', '... | 29,710,724 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D08.811.277.656.300.032'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['A08... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative in vivo characterization of intracellular and extracellular pH profiles in heterogeneous tumors: a novel method enabling multiparametric pH analysis. | Acid production and transport are currently being studied to identify new targets for efficient cancer treatment, as subpopulations of tumor cells frequently escape conventional therapy owing to their particularly acidic tumor microenvironment. Heterogeneity in intracellular and extracellular tumor pH (pHi, pHe) has be... | ['Animals', 'Cricetinae', 'Hydrogen-Ion Concentration', 'Magnetic Resonance Spectroscopy', 'Mice', 'Neoplasms, Experimental', 'Xenograft Model Antitumor Assays'] | 23,752,692 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['G02.300'], ['E05.196.867.519'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.619', 'E05.598.500.496'], ['E05.337.550.200.900', 'E05.624.850']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A statistical study of the interventional results of endodontic treatment performed in the Odontostomatology Department in Dakar]. | The long-term of endodontic treatment performed by under graduated students in Dakar were assessed. The overall success rate was 83.84% Vital teeth showed better results than the non vital teeth (necrosis). | ['Adult', 'Age Factors', 'Chi-Square Distribution', 'Dental Pulp Necrosis', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mandible', 'Maxilla', 'Middle Aged', 'Periapical Diseases', 'Pulpitis', 'Root Canal Obturation', 'Root Canal Therapy', 'Schools, Dental', 'Senegal', 'Sex Factors', 'Tooth', 'Treatment Outcome'] | 11,372,115 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C07.793.237.315', 'C23.550.717.182'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Craniofacial mucormycosis: computed tomographic and angiographic findings in two cases. | Two cases of craniofacial mucormycosis are presented, stressing computed tomographic (CT) and angiographic findings. In the first case, successful embolization of a sphenopalatine artery pseudoaneurysm is shown. The second case demonstrates CT findings of ethmoidal sinus and frontal lobe inflammatory change. Ophthalmic... | ['Adult', 'Arterial Occlusive Diseases', 'Face', 'Female', 'Head', 'Humans', 'Male', 'Mucormycosis', 'Ophthalmic Artery', 'Paranasal Sinus Diseases', 'Tomography, X-Ray Computed'] | 7,232,728 | [['M01.060.116'], ['C14.907.137'], ['A01.456.505'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.703.980.600'], ['A07.015.114.622'], ['C08.460.692', 'C09.603.692'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.81... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical associations of anosognosia in mild cognitive impairment and Alzheimer's disease. | AIMS AND OBJECTIVE: While loss of insight of cognitive deficits is a common phenomenon in patients with Alzheimer's disease (AD), there is a lack of consensus regarding the presence of impaired insight among patients with mild cognitive impairment (MCI). We aim to investigate the clinical, cognitive, and behavioral ass... | ['Adult', 'Aged', 'Agnosia', 'Alzheimer Disease', 'Apathy', 'Case-Control Studies', 'Cognition', 'Cognitive Dysfunction', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Psychiatric Status Rating Scales'] | 25,754,519 | [['M01.060.116'], ['M01.060.116.100'], ['C10.597.606.762.100', 'C23.888.592.604.764.100', 'F01.700.750.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F01.470.137'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F02.463.188'], ['F03.615.250.700'], ['B01.050.150... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anti-angiogenic role of angiostatin during corneal wound healing. | The purpose of this study is to determine whether angiostatin is involved in maintaining corneal avascularity after wounding. We generated polyclonal rabbit anti-mouse angiostatin antibodies directed against each of the five kringle domains, (K1-5) and anti-mouse plasmin B chain antibodies. Mouse corneas were immunosta... | ['Angiostatins', 'Animals', 'Cells, Cultured', 'Corneal Neovascularization', 'Endothelium, Vascular', 'Epithelium, Corneal', 'Female', 'Lasers, Excimer', 'Mice', 'Mice, Inbred C57BL', 'Photorefractive Keratectomy', 'Plasminogen', 'Rabbits', 'Rats', 'Rats, Sprague-Dawley', 'Wound Healing'] | 15,106,938 | [['D08.622.610.500', 'D12.644.276.100.450.500', 'D12.776.124.790.223.580.500', 'D12.776.377.715.182.580.500', 'D12.776.467.100.450.500', 'D12.776.811.243.610.500', 'D23.529.100.450.500'], ['B01.050'], ['A11.251'], ['C11.204.290', 'C23.550.589.500.435'], ['A07.015.700.500', 'A10.272.491.355'], ['A09.371.060.217.325', 'A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of Metformin on Spatial and Verbal Memory in Children with ASD and Overweight Associated with Atypical Antipsychotic Use. | OBJECTIVES: Studies in humans and rodents suggest that metformin, a medicine typically used to treat type 2 diabetes, may have beneficial effects on memory. We sought to determine whether metformin improved spatial or verbal memory in children with autism spectrum disorder (ASD) and overweight associated with atypical ... | ['Adolescent', 'Antipsychotic Agents', 'Autism Spectrum Disorder', 'Child', 'Double-Blind Method', 'Female', 'Humans', 'Hypoglycemic Agents', 'Male', 'Memory', 'Metformin', 'Overweight', 'Spatial Memory', 'Treatment Outcome'] | 29,620,914 | [['M01.060.057'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F03.625.164.113'], ['M01.060.406'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['F02.463.425.540... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Photosystem II core quenching in desiccated Leptolyngbya ohadii. | Cyanobacteria living in the harsh environment of the desert have to protect themselves against high light intensity and prevent photodamage. These cyanobacteria are in a desiccated state during the largest part of the day when both temperature and light intensity are high. In the desiccated state, their photosynthetic ... | ['Cyanobacteria', 'Desiccation', 'Image Processing, Computer-Assisted', 'Photosystem II Protein Complex', 'Spectrometry, Fluorescence', 'Temperature', 'Time Factors'] | 31,535,258 | [['B03.280', 'B03.440.475.100'], ['E05.196.335', 'G02.176'], ['L01.224.308'], ['D05.500.562.488.750', 'D08.811.600.710.750', 'D12.776.543.930.500.750', 'D12.776.765.199.750.750.750'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Relationships between the size of the adenoids and the dental arch measurements]. | INTRODUCTION: Enlarged adenoids are often associated with oral breathing. The latter can impact the dental arches. The purpose of this study was to determine the relationships between dental arch measurements and the size of adenoids.MATERIALS AND METHODS: A cross-sectional study was carried out on 86 children. The dim... | ['Adenoids', 'Cephalometry', 'Child', 'Cross-Sectional Studies', 'Dental Arch', 'Female', 'Humans', 'Hypertrophy', 'Male', 'Nasopharynx', 'Odontometry', 'Organ Size', 'Overbite'] | 30,565,559 | [['A04.623.557.500', 'A10.549.100', 'A14.724.557.500', 'A15.382.520.604.100'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A02.835.232.781.324.502.320', 'A14.521.320'], ['B01.050.150.900.649.313.988.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kinetics of antibiotics release from ceramic implants. | Presented study describes kinetics of antibiotics release: cefazolin, gentamicin, netilmicin and vancomycin, from two types of ceramic implants: corundum and apatite cement prepared for osteosurgery. The experiments was based on our experimental model developed previously, in which the extraction of antibiotics from im... | ['Aluminum Oxide', 'Anti-Bacterial Agents', 'Apatites', 'Cefazolin', 'Ceramics', 'Drug Implants', 'Gentamicins', 'Netilmicin', 'Polyurethanes', 'Spectrophotometry', 'Surgical Sponges', 'Vancomycin'] | 14,696,519 | [['D01.056.050', 'D01.650.550.050'], ['D27.505.954.122.085'], ['D01.029.260.700.675.374.075.025', 'D01.146.360.050', 'D01.578.122', 'D01.695.625.675.650.075.025'], ['D02.065.589.099.249.160', 'D02.886.665.074.160', 'D03.633.100.300.249.160'], ['J01.637.153'], ['D26.255.210.315'], ['D09.408.051.374'], ['D09.408.051.374.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
L-asparaginase from developing seeds of Lupinus arboreus. | Asparaginase (EC 3.5.1.1) activity reached a maximum 40 days post anthesis in developing seeds of Lupinus arboreus and this correlated with the appearance of other ammonia assimilatory enzymes. Asparaginase, purified from these developing seeds, was resolved into three isoforms, designated asparaginases A, B and C. A m... | ['Amino Acid Sequence', 'Ammonia', 'Asparaginase', 'Chromatography, Affinity', 'Chromatography, Liquid', 'Isoelectric Focusing', 'Isoenzymes', 'Molecular Sequence Data', 'Plants', 'Precipitin Tests', 'Seeds'] | 1,368,361 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D01.362.075', 'D01.625.050'], ['D08.811.277.087.116'], ['E05.196.181.400.170'], ['E05.196.181.400'], ['E05.196.401.663', 'E05.301.300.663'], ['D08.811.348', 'D12.776.800.300'], ['L01.453.245.667'], ['B01.650'], ['E01.370.225.812.735.645', 'E05.196.150.639.500', 'E05.200.81... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Establishment and characterization of a human papillomavirus type 16-positive tonsillar carcinoma xenograft in BALB/c nude mice. | BACKGROUND: Among head and neck cancers, human papillomavirus type 16 (HPV16) is associated with tonsillar carcinomas. Despite this, no HPV16-positive tonsillar cancer cell line has been established in nude mice.METHODS: Fresh tonsillar carcinoma biopsies were obtained from 23 patients and implanted subcutaneously into... | ['Aged', 'Animals', 'Cell Line, Tumor', 'Female', 'Heterografts', 'Human papillomavirus 16', 'Humans', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Papillomavirus Infections', 'Reverse Transcriptase Polymerase Chain Reaction', 'Tonsillar Neoplasms', 'Viral Load'] | 25,352,201 | [['M01.060.116.100'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['A01.941.875'], ['B04.280.210.655.050.616', 'B04.613.204.655.050.616'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.15... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Plasma NT-proBNP is independently associated with albuminuria in type 2 diabetes. | OBJECTIVE: The aim of this study is to investigate the relationship between plasma NH2-terminal pro-brain natriuretic peptide (NT-proBNP) levels and diabetic nephropathy in type 2 diabetic patients.METHODS: The records of 983 patients with type 2 diabetes hospitalized in the Endocrinology and Metabolism Department of P... | ['Albuminuria', 'China', 'Cohort Studies', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Diabetic Nephropathies', 'Diabetic Retinopathy', 'Disease Progression', 'Female', 'Glycated Hemoglobin A', 'Hospitals, University', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Natriuretic P... | 26,922,580 | [['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['Z01.252.474.164'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.... | ['Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The impact of intensive health promotion to a targeted refugee population on utilisation of a new refugee paediatric clinic at the children's hospital at Westmead. | OBJECTIVE: To evaluate the impact of intensive promotion of a new health service to a targeted refugee population, recently resettled in Sydney, and the role of early social connection and membership of social group in promoting health service utilisation of refugees.DESIGN: Descriptive epidemiological study and survey... | ['Adult', 'Africa South of the Sahara', 'Child', 'Health Knowledge, Attitudes, Practice', 'Health Promotion', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Hospitals, Pediatric', 'Humans', 'Interviews as Topic', 'Middle Aged', 'Needs Assessment', 'New South Wales', 'Outpatient Clinics, Hospital'... | 19,370,438 | [['M01.060.116'], ['Z01.058.290'], ['M01.060.406'], ['F01.100.150.500', 'N05.300.150.410'], ['I02.233.332.445', 'N02.421.726.407.579'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['N02.278.421.556.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520',... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Early Predictors of Long-term Outcomes in Childhood Glaucoma. | PURPOSE: A data-based staging system for childhood glaucoma is likely to improve the prediction of visual acuity and intraocular pressure (IOP) control outcomes. We investigated early clinical factors associated with poor long-term visual, and IOP control outcomes in early-onset glaucoma as the initial steps to constru... | ['Antihypertensive Agents', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Hydrophthalmos', 'Infant', 'Intraocular Pressure', 'Male', 'Models, Statistical', 'Pilot Projects', 'Retrospective Studies', 'Tonometry, Ocular', 'Trabeculectomy', 'Treatment Outcome', 'Visual Acuity'] | 30,059,407 | [['D27.505.954.411.162'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.250.480', 'C11.525.381.407.480', 'C16.131.384.480', 'C16.614.438'], ['M01.060.703'], ['G14.440'], ['E05.318.740.500', 'E05.599.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Results of surgical correction of kyphotic deformities of the spine in ankylosing spondylitis on the basis of the modified arthritis impact measurement scales. | STUDY DESIGN: This is a retrospective study of patient outcome in ankylosing spondylitis patients with fixed kyphotic deformities of the spine who underwent reconstructive surgery.OBJECTIVES: To measure the multidimensional effects of reconstructive spinal osteotomy in this patient group with a questionnaire-based inst... | ['Activities of Daily Living', 'Anxiety', 'Arthritis', 'Depression', 'Health Status Indicators', 'Humans', 'Kyphosis', 'Pain', 'Radiography', 'Retrospective Studies', 'Social Behavior', 'Spondylitis, Ankylosing', 'Treatment Outcome'] | 7,570,177 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.470.132'], ['C05.550.114'], ['F01.145.126.350'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.800.500'], ['C23.888.592.612', 'F02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Quercetin inhibits Shc- and phosphatidylinositol 3-kinase-mediated c-Jun N-terminal kinase activation by angiotensin II in cultured rat aortic smooth muscle cells. | Angiotensin II (Ang II) induces vascular smooth muscle cell (VSMC) hypertrophy, which results in various cardiovascular diseases. Ang II-induced cellular events have been implicated, in part, in the activation of mitogen-activated protein (MAP) kinases. Although it has been proposed that daily intake of bioflavonoids b... | ['Angiotensin II', 'Animals', 'Chromones', 'Collagen', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Enzyme Activation', 'Enzyme Inhibitors', 'Humans', 'JNK Mitogen-Activated Protein Kinases', 'Leucine', 'Male', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Mitogen-Activated P... | 11,562,426 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['G02.111... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Projections of the dorsal raphe nucleus and midbrain central gray substance to the cat limbic system]. | Morphological organization of connections of ventro-lateral (nociceptive) and dorso-lateral (analgetic) midbrain central gray (vl SGC and dl SGC), as well as of dorsal raphe nucleus (analgetic zone, Rd), with different limbic structures, responsible for the formation of various emotional states, was studied in 26 cats.... | ['Afferent Pathways', 'Animals', 'Cats', 'Hypothalamus', 'Limbic System', 'Microscopy, Electron', 'Periaqueductal Gray', 'Raphe Nuclei', 'Synaptic Transmission', 'Ultrasonography'] | 14,628,552 | [['A08.612.220'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A08.186.211.180'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.186.211.132.659.413.875.595'], ['A08.186.211.132.659.413.875.618', 'A08.186.211.132.810.428.600.650.562', 'A08.186.211.13... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Fibrinolytic activity of the human brain and the cerebrospinal fluid]. | The fibrinolytic activity (F.A.) of the encephalon, the cerebrospinal fluid and the choroid plexi has been studied in 15 necropsies observed at the Pavia Forensic Medicine Department. A physiopathological relationship between the F.A. of CSF and the encephalic structures is suggested; against this, there would appear t... | ['Adolescent', 'Adult', 'Aged', 'Brain Chemistry', 'Child', 'Choroid Plexus', 'Female', 'Fibrinolysis', 'Fibrinolytic Agents', 'Humans', 'Male', 'Middle Aged'] | 7,224,839 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G02.111.150', 'G03.185'], ['M01.060.406'], ['A08.186.211.140.298'], ['G09.188.390.150.390'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Epidemiological features and risk factor analysis of children with acute lung injury. | BACKGROUND: Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) represents a devastating complication observed in critical care medicine. The purpose of this study is to investigate the epidemiological aspects of ALI/ARDS in pediatric intensive care unit (PICU) and risk factors of mortality.METHODS: Pati... | ['Acute Lung Injury', 'Adolescent', 'Child', 'Child, Preschool', 'China', 'Female', 'Follow-Up Studies', 'Hospitals, Pediatric', 'Hospitals, University', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Intensive Care Units', 'Logistic Models', 'Male', 'Prevalence', 'Prospective Studies', 'Respiratory Distress Synd... | 22,282,381 | [['C08.381.520.500'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.278.421.556.437'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318... | ['Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP. | Glucosamine, which enters the hexosamine pathway downstream of the rate-limiting step, has been routinely used to mimic the insulin resistance caused by high glucose and insulin. We investigated the effect of glucosamine on insulin-stimulated glucose transport in 3T3-L1 adipocytes. The Delta-insulin (insulin-stimulated... | ['3T3 Cells', 'Adenosine Triphosphate', 'Adipocytes', 'Animals', 'Cell Fractionation', 'Deoxyglucose', 'Glucosamine', 'Glucose', 'Glucose Transporter Type 1', 'Glucose Transporter Type 4', 'Inosine', 'Insulin Receptor Substrate Proteins', 'Insulin Resistance', 'Mice', 'Monosaccharide Transport Proteins', 'Muscle Protei... | 9,685,425 | [['A11.251.210.100', 'A11.329.228.100'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.329.114'], ['B01.050'], ['E05.242.251'], ['D09.254.229'], ['D09.067.342.531'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500.500', 'D12.776.157.530.937.563.500', 'D12.776.543.585.500.500.50... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new species of Duttaphrynus (Anura:Bufonidae) from Northeast India. | A new species of montane toad Duttaphrynus is described from Nagaland state of Northeast India. The new species is diagnosable based on following combination of characters: absence of preorbital, postorbital and orbitotympanic ridges, elongated and broad parotid gland, first finger longer than second and presence of a ... | ['Animals', 'Biodiversity', 'Bufonidae', 'Female', 'India', 'Male', 'Sexual Behavior, Animal'] | 26,213,769 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B01.050.150.900.090.180.210'], ['Z01.252.245.393'], ['F01.145.113.252.748']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Functional Domains of ZFP809 Essential for Nuclear Localization and Gene Silencing. | Zinc finger protein 809 (ZFP809) is a member of the Kruppel-associated box-containing zinc finger protein (KRAB-ZFP) family, and is highly expressed in mouse immature cells. ZFP809 is known to inhibit the expression of transduced genes driven by Moloney murine leukemia virus (MoMLV)-typed retroviral vectors by binding ... | ['Animals', 'Binding Sites', 'Blotting, Western', 'Cell Nucleus', 'DNA-Binding Proteins', 'Gene Silencing', 'HEK293 Cells', 'Humans', 'Luminescent Proteins', 'Mice', 'Microscopy, Fluorescence', 'Models, Genetic', 'Moloney murine leukemia virus', 'Mutation', 'Nuclear Proteins', 'Protein Binding', 'Repressor Proteins', '... | 26,417,948 | [['B01.050'], ['G02.111.570.120'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.776.260'], ['G05.308.203.374'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of gentamicin by radioimmunoassay. | A sensitive, specific and precise procedure for the measurement of serum gentamicin by radioimmunoassay is presented. The method is rapid, convenient, and highly reliable for this very important measurement. Studies designed to evaluate the validity and reproducibility of the assay are presented and discussed. | ['Gentamicins', 'Humans', 'Microchemistry', 'Radioimmunoassay', 'Reagent Kits, Diagnostic'] | 7,212,629 | [['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.620', 'H01.181.650'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Regio- and stereoselective anomeric esterification of glucopyranose 1,2-diols and a facile preparation of 2-O-acetylated glucopyranosyl trichloroacetimidates from the corresponding 1,2-diols. | A highly regio- and stereoselective anomeric esterification of 3-O-allyl (or benzyl, or benzoyl)-4,6-O-isopropylidene-alpha,beta-d-glucopyranose with acetyl chloride, or allyl chloroformate, or ethyl chloroformate gave the corresponding 2-OH, 1-beta-acetates or -carbonates in excellent yields. The 2-OH, 1-beta-acetates... | ['Acetates', 'Acetonitriles', 'Carbohydrate Conformation', 'Chlorides', 'Esterification', 'Formates', 'Formic Acid Esters', 'Models, Chemical', 'Molecular Structure', 'Oligosaccharides', 'Stereoisomerism'] | 17,300,768 | [['D02.241.081.018', 'D10.251.400.045'], ['D02.626.080'], ['G02.111.570.820.235'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G02.111.270', 'G02.607.250', 'G03.344'], ['D02.241.081.420'], ['D02.241.081.420.750'], ['E05.599.495'], ['G02.111.570', 'G02.466'], ['D09.698.629'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects from lumbar nerve root transection in rats on spinal somatosensory and motor-evoked potentials. | STUDY DESIGN: Spinal somatosensory-evoked potentials (SSEPs), elicited by mixed nerve and dermatomal stimulation, and compound evoked muscle potentials (CMAPs), elicited by lower thoracic interspinous space stimulation, were recorded in rats that underwent single nerve root transection.OBJECTIVES: To investigate and co... | ['Animals', 'Disease Models, Animal', 'Electric Stimulation', 'Electrodiagnosis', 'Evoked Potentials, Motor', 'Evoked Potentials, Somatosensory', 'Lower Extremity', 'Lumbosacral Region', 'Monitoring, Physiologic', 'Predictive Value of Tests', 'Radiculopathy', 'Rats', 'Reaction Time', 'Sciatic Nerve', 'Sensitivity and S... | 14,722,405 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.723.402'], ['E01.370.405'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['A01.378.610'], ['A01.923.176.519'], ['E01.370.520'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.65... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Cardiac inhibitory neurons in gastropod snail Achatina fulica. | Two inhibitory heart motor neurons (HI-1, HI-2) were identified in the visceral ganglion of the snail Achatina fulica. Both motor neurons were connected monosynaptically with the myocardium. Irregular action potentials composed a typical pattern of neuronal spontaneous electrical activity. The neurons shared common exc... | ['Action Potentials', 'Animals', 'Cell Polarity', 'Dendrites', 'Ganglia, Invertebrate', 'Heart', 'Isoquinolines', 'Models, Neurological', 'Motor Neurons', 'Snails', 'Synapses'] | 9,350,497 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['G04.250'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['A08.340.352', 'A13.408'], ['A07.541'], ['D03.633.100.531'], ['E05.599.395.642'], ['A08.675.655.500', 'A11.671.655.500'], ['B01.050.500.644.400.750'], ['A08.850', 'A11.284.149.165.420.78... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acceptance, compliance and effects of compression stockings on venous functional symptoms and quality of life of Italian pregnant women. | AIM: The rates of pregnant women with functional symptoms of venous insufficiency who accepted or refused to wear therapeutic compression stockings were evaluated and compared in relation to their clinical evolution and their compliance levels.METHODS: The observational study was conducted in pregnant women between 4 a... | ['Adult', 'Female', 'Humans', 'Italy', 'Pain', 'Pain Measurement', 'Patient Compliance', 'Pregnancy', 'Pregnancy Complications, Cardiovascular', 'Prospective Studies', 'Quality of Life', 'Stockings, Compression', 'Surveys and Questionnaires', 'Time Factors', 'Treatment Outcome', 'Treatment Refusal', 'Venous Insufficien... | 25,056,167 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E01.370.600.550.324'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['G08.686.784.769'], ['C13.703.634', 'C14.583'], ['E05.318.372.500.75... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adhesion mediated by intercellular adhesion molecule 1 attenuates the potency of antibodies that block HIV-1 gp160-dependent syncytium formation. | Several lines of evidence suggest that leukocyte adhesion molecules can promote HIV-1-mediated cell fusion and syncytium formation. In the present studies, the human kidney cell line, 293, was transfected with the envelope glycoprotein gene of the MN strain of HIV-1 alone or cotransfected with a cDNA encoding intercell... | ['Binding, Competitive', 'Cell Adhesion', 'Cell Fusion', 'Cell Line', 'Cytopathogenic Effect, Viral', 'Gene Products, env', 'Genes, env', 'HIV Antibodies', 'HIV Envelope Protein gp160', 'HIV-1', 'Humans', 'Intercellular Adhesion Molecule-1', 'Lymphocyte Function-Associated Antigen-1', 'Protein Precursors', 'Transfectio... | 7,917,519 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G04.022'], ['E05.242.307', 'G04.155'], ['A11.251.210'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['D12.776.775.320', 'D12.776.964.775.325', 'D12.776.964.970.880.325'], ['G05.360.340.024.340.364.875.172', 'G05.360.340.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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